Co-expression of mu and delta opioid receptors as receptor-G protein fusions enhances both mu and delta signalling via distinct mechanisms

Journal of Neurochemistry

Volumn 105, Issue 3, 2008, Pages 865-873

  Snook, L A ^a,c   Milligan, G ^b   Kieffer, B L ^a   Massotte, D ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

Co expression; G protein coupled receptor; Opioid receptor; Receptor G protein fusion

Indexed keywords

4 [ALPHA (4 ALLYL 2,5 DIMETHYL 1 PIPERAZINYL) 3 METHOXYBENZYL] N,N DIETHYLBENZAMIDE; DELTA OPIATE RECEPTOR; DELTORPHIN; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLARGINYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA SUBUNIT; HYBRID PROTEIN; MU OPIATE RECEPTOR; MU OPIATE RECEPTOR ANTAGONIST; PERTUSSIS TOXIN;

ARTICLE; BINDING AFFINITY; CONTROLLED STUDY; CROSS REACTION; DRUG EFFICACY; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ANALGESICS, OPIOID; CELL LINE; CENTRAL NERVOUS SYSTEM; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HUMANS; NARCOTIC ANTAGONISTS; NEURONS; NOCICEPTORS; OPIOID PEPTIDES; PAIN; PROTEIN BINDING; PROTEIN CONFORMATION; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; RECOMBINANT FUSION PROTEINS; SIGNAL TRANSDUCTION;

EID: 42449147994     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05215.x     Document Type: Article

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