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Volumn 36, Issue 2, 2016, Pages 302-325

Cerebral small vessel disease: Capillary pathways to stroke and cognitive decline

Author keywords

capillary dysfunction; Cerebral small vessel disease; dementia; oxygenation; stroke

Indexed keywords

AMYLOID; HEMOGLOBIN; NICOTINE; NITROGEN OXIDE; OXYGEN; PHOSPHODIESTERASE INHIBITOR;

EID: 84961374240     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1177/0271678X15606723     Document Type: Review
Times cited : (203)

References (247)
  • 1
    • 77953533246 scopus 로고    scopus 로고
    • Cerebral small vessel disease: From pathogenesis and clinical characteristics to therapeutic challenges
    • Pantoni L. Cerebral small vessel disease: from pathogenesis and clinical characteristics to therapeutic challenges. Lancet Neurol 2010; 9: 689-701.
    • (2010) Lancet Neurol , vol.9 , pp. 689-701
    • Pantoni, L.1
  • 2
    • 84880391350 scopus 로고    scopus 로고
    • Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration
    • Wardlaw JM, Smith EE, Biessels GJ, et al. Neuroimaging standards for research into small vessel disease and its contribution to ageing and neurodegeneration. Lancet Neurol 2013; 12: 822-838.
    • (2013) Lancet Neurol , vol.12 , pp. 822-838
    • Wardlaw, J.M.1    Smith, E.E.2    Biessels, G.J.3
  • 3
    • 84872963744 scopus 로고    scopus 로고
    • Blood-brain barrier permeability and long-Term clinical and imaging outcomes in cerebral small vessel disease
    • Wardlaw JM, Doubal FN, Valdes-Hernandez M, et al. Blood-brain barrier permeability and long-Term clinical and imaging outcomes in cerebral small vessel disease. Stroke 2013; 44: 525-527.
    • (2013) Stroke , vol.44 , pp. 525-527
    • Wardlaw, J.M.1    Doubal, F.N.2    Valdes-Hernandez, M.3
  • 4
    • 84876488222 scopus 로고    scopus 로고
    • Mechanisms of sporadic cerebral small vessel disease: Insights from neuroimaging
    • Wardlaw JM, Smith C and Dichgans M. Mechanisms of sporadic cerebral small vessel disease: insights from neuroimaging. Lancet Neurol 2013; 12: 483-497.
    • (2013) Lancet Neurol , vol.12 , pp. 483-497
    • Wardlaw, J.M.1    Smith, C.2    Dichgans, M.3
  • 5
    • 84856460295 scopus 로고    scopus 로고
    • The roles of cerebral blood flow, capillary transit time heterogeneity and oxygen tension in brain oxygenation and metabolism
    • Jespersen SN and Ostergaard L. The roles of cerebral blood flow, capillary transit time heterogeneity and oxygen tension in brain oxygenation and metabolism. J Cereb Blood Flow Metab 2012; 32: 264-277.
    • (2012) J Cereb Blood Flow Metab , vol.32 , pp. 264-277
    • Jespersen, S.N.1    Ostergaard, L.2
  • 6
    • 84877576712 scopus 로고    scopus 로고
    • The role of the cerebral capillaries in acute ischemic stroke: The extended penumbra model
    • Ostergaard L, Jespersen SN, Mouridsen K, et al. The role of the cerebral capillaries in acute ischemic stroke: the extended penumbra model. J Cereb Blood Flow Metab 2013; 33: 635-648.
    • (2013) J Cereb Blood Flow Metab , vol.33 , pp. 635-648
    • Ostergaard, L.1    Jespersen, S.N.2    Mouridsen, K.3
  • 7
    • 84872343218 scopus 로고    scopus 로고
    • The capillary dysfunction hypothesis of Alzheimer?s disease
    • Ostergaard L, Aamand R, Gutierrez-Jimenez E, et al. The capillary dysfunction hypothesis of Alzheimer?s disease. Neurobiol Aging 2013; 34: 1018-1031.
    • (2013) Neurobiol Aging , vol.34 , pp. 1018-1031
    • Ostergaard, L.1    Aamand, R.2    Gutierrez-Jimenez, E.3
  • 8
    • 0019519255 scopus 로고
    • Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo Potentials, limitations, and clinical applications in cerebral ischemic disorders
    • Baron JC, Bousser MG, Comar D, et al. Noninvasive tomographic study of cerebral blood flow and oxygen metabolism in vivo. Potentials, limitations, and clinical applications in cerebral ischemic disorders. Eur Neurol 1981; 20: 273-284.
    • (1981) Eur Neurol , vol.20 , pp. 273-284
    • Baron, J.C.1    Bousser, M.G.2    Comar, D.3
  • 9
    • 0022272565 scopus 로고
    • Regulation of the microcirculation
    • B. W. Zweifach Award lecture
    • Renkin EM. Regulation of the microcirculation. Microvasc Res 1985; 30: 251-263. (B. W. Zweifach Award lecture.
    • (1985) Microvasc Res , vol.30 , pp. 251-263
    • Renkin, E.M.1
  • 10
    • 0032417876 scopus 로고    scopus 로고
    • Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex
    • Kleinfeld D, Mitra PP, Helmchen F, et al. Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex. Proc Natl Acad Sci U S A 1998; 95: 15741-15746.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 15741-15746
    • Kleinfeld, D.1    Mitra, P.P.2    Helmchen, F.3
  • 11
    • 0028290563 scopus 로고
    • Capillary perfusion of the rat brain cortex An in vivo confocal microscopy study
    • Villringer A, Them A, Lindauer U, et al. Capillary perfusion of the rat brain cortex. An in vivo confocal microscopy study. Circ Res 1994; 75: 55-62.
    • (1994) Circ Res , vol.75 , pp. 55-62
    • Villringer, A.1    Them, A.2    Lindauer, U.3
  • 13
    • 0033509609 scopus 로고    scopus 로고
    • Modeling cerebral blood flow and flow heterogeneity from magnetic resonance residue data
    • Ostergaard L, Chesler DA, Weisskoff RM, et al. Modeling cerebral blood flow and flow heterogeneity from magnetic resonance residue data. J Cereb Blood Flow Metab 1999; 19: 690-699.
    • (1999) J Cereb Blood Flow Metab , vol.19 , pp. 690-699
    • Ostergaard, L.1    Chesler, D.A.2    Weisskoff, R.M.3
  • 14
    • 0342369420 scopus 로고    scopus 로고
    • Combined diffusion-weighted and perfusion-weighted flow heterogeneity magnetic resonance imaging in acute stroke
    • Ostergaard L, Sorensen AG, Chesler DA, et al. Combined diffusion-weighted and perfusion-weighted flow heterogeneity magnetic resonance imaging in acute stroke. Stroke 2000; 31: 1097-1103.
    • (2000) Stroke , vol.31 , pp. 1097-1103
    • Ostergaard, L.1    Sorensen, A.G.2    Chesler, D.A.3
  • 15
    • 0037435973 scopus 로고    scopus 로고
    • Cortical electrical stimulation alters erythrocyte perfusion pattern in the cerebral capillary network of the rat
    • Schulte ML, Wood JD and Hudetz AG. Cortical electrical stimulation alters erythrocyte perfusion pattern in the cerebral capillary network of the rat. Brain Res 2003; 963: 81-92.
    • (2003) Brain Res , vol.963 , pp. 81-92
    • Schulte, M.L.1    Wood, J.D.2    Hudetz, A.G.3
  • 16
    • 0029908654 scopus 로고    scopus 로고
    • Decreased heterogeneity of capillary plasma flow in the rat whisker-barrel cortex during functional hyperemia
    • Vogel J and Kuschinsky W. Decreased heterogeneity of capillary plasma flow in the rat whisker-barrel cortex during functional hyperemia. J Cereb Blood Flow Metab 1996; 16: 1300-1306.
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 1300-1306
    • Vogel, J.1    Kuschinsky, W.2
  • 17
    • 84938533107 scopus 로고    scopus 로고
    • The effects of transit time heterogeneity on brain oxygenation during rest and functional activation
    • Rasmussen PM, Jespersen SN and Ostergaard L. The effects of transit time heterogeneity on brain oxygenation during rest and functional activation. J Cereb Blood Flow Metab 2015; 35: 432-442.
    • (2015) J Cereb Blood Flow Metab , vol.35 , pp. 432-442
    • Rasmussen, P.M.1    Jespersen, S.N.2    Ostergaard, L.3
  • 18
    • 33749860102 scopus 로고    scopus 로고
    • Bidirectional control of CNS capillary diameter by pericytes
    • Peppiatt CM, Howarth C, Mobbs P, et al. Bidirectional control of CNS capillary diameter by pericytes. Nature 2006; 443: 700-704.
    • (2006) Nature , vol.443 , pp. 700-704
    • Peppiatt, C.M.1    Howarth, C.2    Mobbs, P.3
  • 19
    • 84897564199 scopus 로고    scopus 로고
    • Capillary pericytes regulate cerebral blood flow in health and disease
    • Hall CN, Reynell C, Gesslein B, et al. Capillary pericytes regulate cerebral blood flow in health and disease. Nature 2014; 508: 55-60.
    • (2014) Nature , vol.508 , pp. 55-60
    • Hall, C.N.1    Reynell, C.2    Gesslein, B.3
  • 20
    • 1842459327 scopus 로고    scopus 로고
    • Cerebral perfusion imaging by bolus tracking
    • Ostergaard L. Cerebral perfusion imaging by bolus tracking. Top Magn Reson Imaging 2004; 15: 3-9.
    • (2004) Top Magn Reson Imaging , vol.15 , pp. 3-9
    • Ostergaard, L.1
  • 21
    • 84928827390 scopus 로고    scopus 로고
    • The effects of capillary transit time heterogeneity (cth) on brain oxygenation
    • Angleys H, Ostergaard L and Jespersen SN. The effects of capillary transit time heterogeneity (cth) on brain oxygenation. J Cereb Blood Flow Metab 2015; 35: 806-817.
    • (2015) J Cereb Blood Flow Metab , vol.35 , pp. 806-817
    • Angleys, H.1    Ostergaard, L.2    Jespersen, S.N.3
  • 23
    • 0014022317 scopus 로고
    • The luxury-perfusion syndrome its possible relation to acute metabolic acidosis localised within the brain
    • Lassen NA. The luxury-perfusion syndrome and its possible relation to acute metabolic acidosis localised within the brain. Lancet 1966; 2: 1113-1115.
    • (1966) Lancet , vol.2 , pp. 1113-1115
    • Lassen, N.A.1
  • 24
    • 69949172891 scopus 로고    scopus 로고
    • Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery
    • Yemisci M, Gursoy-Ozdemir Y, Vural A, et al. Pericyte contraction induced by oxidative-nitrative stress impairs capillary reflow despite successful opening of an occluded cerebral artery. Nat Med 2009; 15: 1031-1037.
    • (2009) Nat Med , vol.15 , pp. 1031-1037
    • Yemisci, M.1    Gursoy-Ozdemir, Y.2    Vural, A.3
  • 25
    • 84871251698 scopus 로고    scopus 로고
    • 2012 Revised international Chapel Hill consensus conference nomenclature of vasculitides
    • Jennette JC, Falk RJ, Bacon PA, et al. 2012 Revised international Chapel Hill consensus conference nomenclature of vasculitides. Arthritis Rheum 2013; 65: 1-11.
    • (2013) Arthritis Rheum , vol.65 , pp. 1-11
    • Jennette, J.C.1    Falk, R.J.2    Bacon, P.A.3
  • 26
    • 2642517929 scopus 로고    scopus 로고
    • Vasculitis of the nervous system
    • Younger DS. Vasculitis of the nervous system. Curr Opin Neurol 2004; 17: 317-336.
    • (2004) Curr Opin Neurol , vol.17 , pp. 317-336
    • Younger, D.S.1
  • 27
    • 25444463573 scopus 로고    scopus 로고
    • Endothelial/ pericyte interactions
    • Armulik A, Abramsson A and Betsholtz C. Endothelial/ pericyte interactions. Circ Res 2005; 97: 512-523.
    • (2005) Circ Res , vol.97 , pp. 512-523
    • Armulik, A.1    Abramsson, A.2    Betsholtz, C.3
  • 28
    • 78649467527 scopus 로고    scopus 로고
    • Pericytes regulate the blood-brain barrier
    • Armulik A, Genove G, Mae M, et al. Pericytes regulate the blood-brain barrier. Nature 2010; 468: 557-561.
    • (2010) Nature , vol.468 , pp. 557-561
    • Armulik, A.1    Genove, G.2    Mae, M.3
  • 29
    • 0033407485 scopus 로고    scopus 로고
    • Brain macrophages: On the role of pericytes and perivascular cells
    • Thomas WE. Brain macrophages: on the role of pericytes and perivascular cells. Brain Res Brain Res Rev 1999; 31: 42-57.
    • (1999) Brain Res Brain Res Rev , vol.31 , pp. 42-57
    • Thomas, W.E.1
  • 30
  • 31
    • 8644219667 scopus 로고    scopus 로고
    • Notch3 is required for arterial identity and maturation of vascular smooth muscle cells
    • Domenga V, Fardoux P, Lacombe P, et al. Notch3 is required for arterial identity and maturation of vascular smooth muscle cells. Genes Dev 2004; 18: 2730-2735.
    • (2004) Genes Dev , vol.18 , pp. 2730-2735
    • Domenga, V.1    Fardoux, P.2    Lacombe, P.3
  • 32
    • 16244380158 scopus 로고    scopus 로고
    • Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro
    • Morrow D, Sweeney C, Birney YA, et al. Cyclic strain inhibits Notch receptor signaling in vascular smooth muscle cells in vitro. Circ Res 2005; 96: 567-575.
    • (2005) Circ Res , vol.96 , pp. 567-575
    • Morrow, D.1    Sweeney, C.2    Birney, Y.A.3
  • 33
    • 79956356333 scopus 로고    scopus 로고
    • Notch3 is essential for regulation of the renal vascular tone
    • Boulos N, Helle F, Dussaule JC, et al. Notch3 is essential for regulation of the renal vascular tone. Hypertension 2011; 57: 1176-1182.
    • (2011) Hypertension , vol.57 , pp. 1176-1182
    • Boulos, N.1    Helle, F.2    Dussaule, J.C.3
  • 34
    • 84937414504 scopus 로고    scopus 로고
    • Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes
    • Hill RA, Tong L, Yuan P, et al. Regional blood flow in the normal and ischemic brain is controlled by arteriolar smooth muscle cell contractility and not by capillary pericytes. Neuron 2015; 87: 95-110.
    • (2015) Neuron , vol.87 , pp. 95-110
    • Hill, R.A.1    Tong, L.2    Yuan, P.3
  • 35
    • 78650645093 scopus 로고    scopus 로고
    • Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain
    • Fernandez-Klett F, Offenhauser N, Dirnagl U, et al. Pericytes in capillaries are contractile in vivo, but arterioles mediate functional hyperemia in the mouse brain. Proc Natl Acad Sci U S A 2010; 107: 22290-22295.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 22290-22295
    • Fernandez-Klett, F.1    Offenhauser, N.2    Dirnagl, U.3
  • 37
    • 33645730887 scopus 로고    scopus 로고
    • Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature
    • Yamanishi S, Katsumura K, Kobayashi T, et al. Extracellular lactate as a dynamic vasoactive signal in the rat retinal microvasculature. Am J Physiol Heart Circ Physiol 2006; 290: H925-H934.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H925-H934
    • Yamanishi, S.1    Katsumura, K.2    Kobayashi, T.3
  • 38
    • 11344256587 scopus 로고    scopus 로고
    • Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina
    • Kawamura H, Kobayashi M, Li Q, et al. Effects of angiotensin II on the pericyte-containing microvasculature of the rat retina. J Physiol 2004; 561: 671-683.
    • (2004) J Physiol , vol.561 , pp. 671-683
    • Kawamura, H.1    Kobayashi, M.2    Li, Q.3
  • 39
    • 0345698791 scopus 로고    scopus 로고
    • In situ observation of living pericytes in rat retinal capillaries
    • Schonfelder U, Hofer A, Paul M, et al. In situ observation of living pericytes in rat retinal capillaries. Microvasc Res 1998; 56: 22-29.
    • (1998) Microvasc Res , vol.56 , pp. 22-29
    • Schonfelder, U.1    Hofer, A.2    Paul, M.3
  • 40
    • 68849128539 scopus 로고    scopus 로고
    • Pericytes Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche
    • Diaz-Flores L, Gutierrez R, Madrid JF, et al. Pericytes. Morphofunction, interactions and pathology in a quiescent and activated mesenchymal cell niche. Histol Histopathol 2009; 24: 909-969.
    • (2009) Histol Histopathol , vol.24 , pp. 909-969
    • Diaz-Flores, L.1    Gutierrez, R.2    Madrid, J.F.3
  • 41
    • 0031442959 scopus 로고    scopus 로고
    • Adenosineinduced relaxation of cultured bovine retinal pericytes
    • Matsugi T, Chen Q and Anderson DR. Adenosineinduced relaxation of cultured bovine retinal pericytes. Invest Ophthalmol Vis Sci 1997; 38: 2695-2701.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 2695-2701
    • Matsugi, T.1    Chen, Q.2    Anderson, D.R.3
  • 42
    • 0141535361 scopus 로고    scopus 로고
    • ATP: A vasoactive signal in the pericyte-containing microvasculature of the rat retina
    • Kawamura H, Sugiyama T, Wu DM, et al. ATP: a vasoactive signal in the pericyte-containing microvasculature of the rat retina. J Physiol 2003; 551: 787-799.
    • (2003) J Physiol , vol.551 , pp. 787-799
    • Kawamura, H.1    Sugiyama, T.2    Wu, D.M.3
  • 43
    • 0028222205 scopus 로고
    • Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway
    • Haefliger IO, Zschauer A and Anderson DR. Relaxation of retinal pericyte contractile tone through the nitric oxide-cyclic guanosine monophosphate pathway. Invest Ophthalmol Vis Sci 1994; 35: 991-997.
    • (1994) Invest Ophthalmol Vis Sci , vol.35 , pp. 991-997
    • Haefliger, I.O.1    Zschauer, A.2    Anderson, D.R.3
  • 44
    • 0030807620 scopus 로고    scopus 로고
    • Oxygen modulation of guanylate cyclase-mediated retinal pericyte relaxations with 3-morpholino-sydnonimine and atrial natriuretic peptide
    • Haefliger IO and Anderson DR. Oxygen modulation of guanylate cyclase-mediated retinal pericyte relaxations with 3-morpholino-sydnonimine and atrial natriuretic peptide. Invest Ophthalmol Vis Sci 1997; 38: 1563-1568.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 1563-1568
    • Haefliger, I.O.1    Anderson, D.R.2
  • 45
    • 0037767378 scopus 로고    scopus 로고
    • Cholinergic regulation of pericyte-containing retinal microvessels
    • Wu DM, Kawamura H, Sakagami K, et al. Cholinergic regulation of pericyte-containing retinal microvessels. Am J Physiol Heart Circ Physiol 2003; 284: H2083-H2090.
    • (2003) Am J Physiol Heart Circ Physiol , vol.284 , pp. H2083-H2090
    • Wu, D.M.1    Kawamura, H.2    Sakagami, K.3
  • 46
    • 78149425848 scopus 로고    scopus 로고
    • Glial and neuronal control of brain blood flow
    • Attwell D, Buchan AM, Charpak S, et al. Glial and neuronal control of brain blood flow. Nature 2010; 468: 232-243.
    • (2010) Nature , vol.468 , pp. 232-243
    • Attwell, D.1    Buchan, A.M.2    Charpak, S.3
  • 47
    • 16044362074 scopus 로고    scopus 로고
    • Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia
    • Joutel A, Corpechot C, Ducros A, et al. Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia. Nature 1996; 383: 707-710.
    • (1996) Nature , vol.383 , pp. 707-710
    • Joutel, A.1    Corpechot, C.2    Ducros, A.3
  • 48
    • 17644438177 scopus 로고    scopus 로고
    • The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients
    • Joutel A, Andreux F, Gaulis S, et al. The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients. J Clin Invest 2000; 105: 597-605.
    • (2000) J Clin Invest , vol.105 , pp. 597-605
    • Joutel, A.1    Andreux, F.2    Gaulis, S.3
  • 49
    • 84866629970 scopus 로고    scopus 로고
    • Pericytes as a new target for pathological processes in CADASIL
    • Dziewulska D and Lewandowska E. Pericytes as a new target for pathological processes in CADASIL. Neuropathology 2012; 32: 515-521.
    • (2012) Neuropathology , vol.32 , pp. 515-521
    • Dziewulska, D.1    Lewandowska, E.2
  • 50
    • 76649118089 scopus 로고    scopus 로고
    • Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease
    • Joutel A, Monet-Lepretre M, Gosele C, et al. Cerebrovascular dysfunction and microcirculation rarefaction precede white matter lesions in a mouse genetic model of cerebral ischemic small vessel disease. J Clin Invest 2010; 120: 433-445.
    • (2010) J Clin Invest , vol.120 , pp. 433-445
    • Joutel, A.1    Monet-Lepretre, M.2    Gosele, C.3
  • 51
    • 84863015729 scopus 로고    scopus 로고
    • Ultrastructural changes in cerebral capillary pericytes in aged Notch3 mutant transgenic mice
    • Gu X, Liu XY, Fagan A, et al. Ultrastructural changes in cerebral capillary pericytes in aged Notch3 mutant transgenic mice. Ultrastruct Pathol 2012; 36: 48-55.
    • (2012) Ultrastruct Pathol , vol.36 , pp. 48-55
    • Gu, X.1    Liu, X.Y.2    Fagan, A.3
  • 52
    • 84891511819 scopus 로고    scopus 로고
    • Notch3 establishes brain vascular integrity by regulating pericyte number
    • Wang Y, Pan L, Moens CB, et al. Notch3 establishes brain vascular integrity by regulating pericyte number. Development 2014; 141: 307-317.
    • (2014) Development , vol.141 , pp. 307-317
    • Wang, Y.1    Pan, L.2    Moens, C.B.3
  • 53
    • 84911002235 scopus 로고    scopus 로고
    • Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease
    • Hill J, Rom S, Ramirez SH, et al. Emerging roles of pericytes in the regulation of the neurovascular unit in health and disease. J Neuroimmune Pharmacol 2014; 9: 591-605.
    • (2014) J Neuroimmune Pharmacol , vol.9 , pp. 591-605
    • Hill, J.1    Rom, S.2    Ramirez, S.H.3
  • 54
    • 84866720642 scopus 로고    scopus 로고
    • Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation
    • Wang S, Cao C, Chen Z, et al. Pericytes regulate vascular basement membrane remodeling and govern neutrophil extravasation during inflammation. PLoS One 2012; 7: e45499.
    • (2012) PLoS One , vol.7 , pp. e45499
    • Wang, S.1    Cao, C.2    Chen, Z.3
  • 55
    • 0033944791 scopus 로고    scopus 로고
    • Pericyte migration from the vascular wall in response to traumatic brain injury
    • Dore-Duffy P, Owen C, Balabanov R, et al. Pericyte migration from the vascular wall in response to traumatic brain injury. Microvasc Res 2000; 60: 55-69.
    • (2000) Microvasc Res , vol.60 , pp. 55-69
    • Dore-Duffy, P.1    Owen, C.2    Balabanov, R.3
  • 56
    • 84865123660 scopus 로고    scopus 로고
    • A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta
    • Iliff JJ, Wang M, Liao Y, et al. A paravascular pathway facilitates CSF flow through the brain parenchyma and the clearance of interstitial solutes, including amyloid beta. Sci Transl Med 2012; 4: 147ra111.
    • (2012) Sci Transl Med , vol.4 , pp. 147ra111
    • Iliff, J.J.1    Wang, M.2    Liao, Y.3
  • 57
    • 40149099870 scopus 로고    scopus 로고
    • Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: Significance for cerebral amyloid angiopathy and neuroimmunology
    • Carare RO, Bernardes-Silva M, Newman TA, et al. Solutes, but not cells, drain from the brain parenchyma along basement membranes of capillaries and arteries: significance for cerebral amyloid angiopathy and neuroimmunology. Neuropathol Appl Neurobiol 2008; 34: 131-144.
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 131-144
    • Carare, R.O.1    Bernardes-Silva, M.2    Newman, T.A.3
  • 58
    • 84913582567 scopus 로고    scopus 로고
    • Impairment of paravascular clearance pathways in the aging brain
    • Kress BT, Iliff JJ, Xia M, et al. Impairment of paravascular clearance pathways in the aging brain. Ann Neurol 2014; 76: 845-861.
    • (2014) Ann Neurol , vol.76 , pp. 845-861
    • Kress, B.T.1    Iliff, J.J.2    Xia, M.3
  • 59
    • 41149157623 scopus 로고    scopus 로고
    • Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer?s disease
    • Weller RO, Subash M, Preston SD, et al. Perivascular drainage of amyloid-beta peptides from the brain and its failure in cerebral amyloid angiopathy and Alzheimer?s disease. Brain Pathol 2008; 18: 253-266.
    • (2008) Brain Pathol , vol.18 , pp. 253-266
    • Weller, R.O.1    Subash, M.2    Preston, S.D.3
  • 60
    • 0034521392 scopus 로고    scopus 로고
    • Clearance of Alzheimer?s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier
    • Shibata M, Yamada S, Kumar SR, et al. Clearance of Alzheimer?s amyloid-ss(1-40) peptide from brain by LDL receptor-related protein-1 at the blood-brain barrier. J Clin Invest 2000; 106: 1489-1499.
    • (2000) J Clin Invest , vol.106 , pp. 1489-1499
    • Shibata, M.1    Yamada, S.2    Kumar, S.R.3
  • 61
    • 73949138881 scopus 로고    scopus 로고
    • Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes
    • Ball KK, Cruz NF, Mrak RE, et al. Trafficking of glucose, lactate, and amyloid-beta from the inferior colliculus through perivascular routes. J Cereb Blood Flow Metab 2010; 30: 162-176.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 162-176
    • Ball, K.K.1    Cruz, N.F.2    Mrak, R.E.3
  • 62
    • 0031017399 scopus 로고    scopus 로고
    • Rapid degeneration of cultured human brain pericytes by amyloid beta protein
    • Verbeek MM, de Waal RM, Schipper JJ, et al. Rapid degeneration of cultured human brain pericytes by amyloid beta protein. J Neurochem 1997; 68: 1135-1141.
    • (1997) J Neurochem , vol.68 , pp. 1135-1141
    • Verbeek, M.M.1    De Waal, R.M.2    Schipper, J.J.3
  • 63
    • 38349026548 scopus 로고    scopus 로고
    • Lipoprotein receptor-related protein-1 mediates amyloid-b-mediated cell death of cerebrovascular cells
    • Wilhelmus MMM, Otte-Höller I, van Triel JJJ, et al. Lipoprotein receptor-related protein-1 mediates amyloid-b-mediated cell death of cerebrovascular cells. Am J Pathol 2007; 171: 1989-1999.
    • (2007) Am J Pathol , vol.171 , pp. 1989-1999
    • Wilhelmus, M.M.M.1    Otte-Höller, I.2    Van Triel, J.J.J.3
  • 64
    • 84861418194 scopus 로고    scopus 로고
    • Apolipoprotein e controls cerebrovascular integrity via cyclophilin A
    • Bell RD, Winkler EA, Singh I, et al. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature 2012; 485: 512-516.
    • (2012) Nature , vol.485 , pp. 512-516
    • Bell, R.D.1    Winkler, E.A.2    Singh, I.3
  • 65
    • 78049279739 scopus 로고    scopus 로고
    • Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
    • Bell RD, Winkler EA, Sagare AP, et al. Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 2010; 68: 409-427.
    • (2010) Neuron , vol.68 , pp. 409-427
    • Bell, R.D.1    Winkler, E.A.2    Sagare, A.P.3
  • 66
    • 78049253786 scopus 로고    scopus 로고
    • Pericyte-mediated regulation of capillary diameter: A component of neurovascular coupling in health and disease
    • Hamilton NB, Attwell D and Hall CN. Pericyte-mediated regulation of capillary diameter: a component of neurovascular coupling in health and disease. Frontiers in Neuroenergetics 2010; 2: 1-15.
    • (2010) Frontiers in Neuroenergetics , vol.2 , pp. 1-15
    • Hamilton, N.B.1    Attwell, D.2    Hall, C.N.3
  • 67
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • Winkler EA, Bell RD and Zlokovic BV. Central nervous system pericytes in health and disease. Nat Neurosci 2011; 14: 1398-1405.
    • (2011) Nat Neurosci , vol.14 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 68
    • 0025779483 scopus 로고
    • A review of hemoglobin and the pathogenesis of cerebral vasospasm
    • Macdonald RL and Weir BK. A review of hemoglobin and the pathogenesis of cerebral vasospasm. Stroke 1991; 22: 971-982.
    • (1991) Stroke , vol.22 , pp. 971-982
    • Macdonald, R.L.1    Weir, B.K.2
  • 69
    • 11044230424 scopus 로고    scopus 로고
    • Delayed cerebral vasospasm and nitric oxide: Review, new hypothesis, and proposed treatment
    • Pluta RM. Delayed cerebral vasospasm and nitric oxide: review, new hypothesis, and proposed treatment. Pharmacol Ther 2005; 105: 23-56.
    • (2005) Pharmacol Ther , vol.105 , pp. 23-56
    • Pluta, R.M.1
  • 70
    • 0022640297 scopus 로고
    • Superoxide anion is involved in the breakdown of endotheliumderived vascular relaxing factor
    • Gryglewski RJ, Palmer RM and Moncada S. Superoxide anion is involved in the breakdown of endotheliumderived vascular relaxing factor. Nature 1986; 320: 454-456.
    • (1986) Nature , vol.320 , pp. 454-456
    • Gryglewski, R.J.1    Palmer, R.M.2    Moncada, S.3
  • 71
    • 0037027485 scopus 로고    scopus 로고
    • Perivascular superoxide anion contributes to impairment of endotheliumdependent relaxation: Role of gp91(phox)
    • Rey FE, Li XC, Carretero OA, et al. Perivascular superoxide anion contributes to impairment of endotheliumdependent relaxation: role of gp91(phox). Circulation 2002; 106: 2497-2502.
    • (2002) Circulation , vol.106 , pp. 2497-2502
    • Rey, F.E.1    Li, X.C.2    Carretero, O.A.3
  • 72
    • 0019507610 scopus 로고
    • The effect of a lipid hydroperoxide of arachidonic acid on the canine basilar artery An experimental study on cerebral vasospasm
    • Sasaki T, Wakai S, Asano T, et al. The effect of a lipid hydroperoxide of arachidonic acid on the canine basilar artery. An experimental study on cerebral vasospasm. J Neurosurg 1981; 54: 357-365.
    • (1981) J Neurosurg , vol.54 , pp. 357-365
    • Sasaki, T.1    Wakai, S.2    Asano, T.3
  • 73
    • 85052609873 scopus 로고    scopus 로고
    • Role of bilirubin oxidation products in the pathophysiology of DIND following SAH
    • Pyne-Geithman GJ, Nair SG, Stamper DN, et al. Role of bilirubin oxidation products in the pathophysiology of DIND following SAH. Acta Neurochir Suppl 2013; 115: 267-273.
    • (2013) Acta Neurochir Suppl , vol.115 , pp. 267-273
    • Pyne-Geithman, G.J.1    Nair, S.G.2    Stamper, D.N.3
  • 74
    • 33645735805 scopus 로고    scopus 로고
    • Connexin40 and connexin43 in mouse aortic endothelium: Evidence for coordinated regulation
    • Isakson BE, Damon DN, Day KH, et al. Connexin40 and connexin43 in mouse aortic endothelium: evidence for coordinated regulation. Am J Physiol Heart Circ Physiol 2006; 290: H1199-H1205.
    • (2006) Am J Physiol Heart Circ Physiol , vol.290 , pp. H1199-H1205
    • Isakson, B.E.1    Damon, D.N.2    Day, K.H.3
  • 75
    • 0024565181 scopus 로고
    • Conduction of vasomotor responses in arterioles: A role for cell-To-cell coupling?
    • Segal SS and Duling BR. Conduction of vasomotor responses in arterioles: a role for cell-To-cell coupling?. Am J Physiol 1989; 256: H838-H845.
    • (1989) Am J Physiol , vol.256 , pp. H838-H845
    • Segal, S.S.1    Duling, B.R.2
  • 76
    • 0023009542 scopus 로고
    • Flow control among microvessels coordinated by intercellular conduction
    • Segal SS and Duling BR. Flow control among microvessels coordinated by intercellular conduction. Science 1986; 234: 868-870.
    • (1986) Science , vol.234 , pp. 868-870
    • Segal, S.S.1    Duling, B.R.2
  • 77
    • 0014735576 scopus 로고
    • Propagated vasodilation in the microcirculation of the hamster cheek pouch
    • Duling BR and Berne RM. Propagated vasodilation in the microcirculation of the hamster cheek pouch. Circ Res 1970; 26: 163-170.
    • (1970) Circ Res , vol.26 , pp. 163-170
    • Duling, B.R.1    Berne, R.M.2
  • 78
    • 77954955587 scopus 로고    scopus 로고
    • The shunt problem: Control of functional shunting in normal and tumour vasculature
    • Pries AR, Hopfner M, le Noble F, et al. The shunt problem: control of functional shunting in normal and tumour vasculature. Nat Rev Cancer 2010; 10: 587-593.
    • (2010) Nat Rev Cancer , vol.10 , pp. 587-593
    • Pries, A.R.1    Hopfner, M.2    Le Noble, F.3
  • 79
    • 0037452135 scopus 로고    scopus 로고
    • Circulating endothelial cells as markers for ANCA-Associated smallvessel vasculitis
    • Woywodt A, Streiber F, de Groot K, et al. Circulating endothelial cells as markers for ANCA-Associated smallvessel vasculitis. Lancet 2003; 361: 206-210.
    • (2003) Lancet , vol.361 , pp. 206-210
    • Woywodt, A.1    Streiber, F.2    De Groot, K.3
  • 80
    • 0029797605 scopus 로고    scopus 로고
    • Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries
    • Vink H and Duling BR. Identification of distinct luminal domains for macromolecules, erythrocytes, and leukocytes within mammalian capillaries. Circ Res 1996; 79: 581-589.
    • (1996) Circ Res , vol.79 , pp. 581-589
    • Vink, H.1    Duling, B.R.2
  • 82
    • 33750856804 scopus 로고    scopus 로고
    • A model for red blood cell motion in glycocalyx-lined capillaries
    • Secomb TW, Hsu R and Pries AR. A model for red blood cell motion in glycocalyx-lined capillaries. Am J Physiol 1998; 274: H1016-H1022.
    • (1998) Am J Physiol , vol.274 , pp. H1016-H1022
    • Secomb, T.W.1    Hsu, R.2    Pries, A.R.3
  • 83
    • 0034975472 scopus 로고    scopus 로고
    • Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL
    • Constantinescu AA, Vink H and Spaan JA. Elevated capillary tube hematocrit reflects degradation of endothelial cell glycocalyx by oxidized LDL. Am J Physiol Heart Circ Physiol 2001; 280: H1051-H1057.
    • (2001) Am J Physiol Heart Circ Physiol , vol.280 , pp. H1051-H1057
    • Constantinescu, A.A.1    Vink, H.2    Spaan, J.A.3
  • 84
    • 0025323252 scopus 로고
    • Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit
    • Desjardins C and Duling BR. Heparinase treatment suggests a role for the endothelial cell glycocalyx in regulation of capillary hematocrit. Am J Physiol 1990; 258: H647-H654.
    • (1990) Am J Physiol , vol.258 , pp. H647-H654
    • Desjardins, C.1    Duling, B.R.2
  • 85
    • 0344872515 scopus 로고    scopus 로고
    • Localization of the permeability barrier to solutes in isolated arteries by confocal microscopy
    • van Haaren PM, VanBavel E, Vink H, et al. Localization of the permeability barrier to solutes in isolated arteries by confocal microscopy. Am J Physiol Heart Circ Physiol 2003; 285: H2848-H2856.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H2848-H2856
    • Van Haaren, P.M.1    VanBavel, E.2    Vink, H.3
  • 86
    • 0037418913 scopus 로고    scopus 로고
    • The endothelial glycocalyx protects against myocardial edema
    • van den Berg BM, Vink H and Spaan JA. The endothelial glycocalyx protects against myocardial edema. Circ Res 2003; 92: 592-594.
    • (2003) Circ Res , vol.92 , pp. 592-594
    • Van Den Berg, B.M.1    Vink, H.2    Spaan, J.A.3
  • 87
    • 0034603747 scopus 로고    scopus 로고
    • Oxidized lipoproteins degrade the endothelial surface layer: Implications for platelet-Endothelial cell adhesion
    • Vink H, Constantinescu AA and Spaan JA. Oxidized lipoproteins degrade the endothelial surface layer: implications for platelet-Endothelial cell adhesion. Circulation 2000; 101: 1500-1502.
    • (2000) Circulation , vol.101 , pp. 1500-1502
    • Vink, H.1    Constantinescu, A.A.2    Spaan, J.A.3
  • 88
    • 0028806512 scopus 로고
    • Ultrastructural demonstration of endothelial glycocalyx disruption in the reperfused rat heart Involvement of oxygen free radicals
    • Czarnowska E and Karwatowska-Prokopczuk E. Ultrastructural demonstration of endothelial glycocalyx disruption in the reperfused rat heart. Involvement of oxygen free radicals. Basic Res Cardiol 1995; 90: 357-364.
    • (1995) Basic Res Cardiol , vol.90 , pp. 357-364
    • Czarnowska, E.1    Karwatowska-Prokopczuk, E.2
  • 89
    • 33745311155 scopus 로고    scopus 로고
    • Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes
    • Nieuwdorp M, Mooij HL, Kroon J, et al. Endothelial glycocalyx damage coincides with microalbuminuria in type 1 diabetes. Diabetes 2006; 55: 1127-1132.
    • (2006) Diabetes , vol.55 , pp. 1127-1132
    • Nieuwdorp, M.1    Mooij, H.L.2    Kroon, J.3
  • 90
    • 0022551973 scopus 로고
    • Early membrane damage during ischemia in rat heart
    • Ishiharajima S, Aida T, Nakagawa R, et al. Early membrane damage during ischemia in rat heart. Exp Mol Pathol 1986; 44: 1-6.
    • (1986) Exp Mol Pathol , vol.44 , pp. 1-6
    • Ishiharajima, S.1    Aida, T.2    Nakagawa, R.3
  • 91
    • 0030271233 scopus 로고    scopus 로고
    • Mechanisms and consequences of cell activation in the microcirculation
    • Mazzoni MC and Schmid-Schonbein GW. Mechanisms and consequences of cell activation in the microcirculation. Cardiovasc Res 1996; 32: 709-719.
    • (1996) Cardiovasc Res , vol.32 , pp. 709-719
    • Mazzoni, M.C.1    Schmid-Schonbein, G.W.2
  • 92
    • 0017738994 scopus 로고
    • Is hyperviscosity a treatable component of diabetic microcirculatory disease?
    • Barnes AJ, Locke P and Scudder PR. Is hyperviscosity a treatable component of diabetic microcirculatory disease?. Lancet 1977; 2: 789-791.
    • (1977) Lancet , vol.2 , pp. 789-791
    • Barnes, A.J.1    Locke, P.2    Scudder, P.R.3
  • 93
    • 2342614850 scopus 로고    scopus 로고
    • Neurovascular regulation in the normal brain and in Alzheimer?s disease
    • Iadecola C. Neurovascular regulation in the normal brain and in Alzheimer?s disease. Nat Rev Neurosci 2004; 5: 347-360.
    • (2004) Nat Rev Neurosci , vol.5 , pp. 347-360
    • Iadecola, C.1
  • 94
    • 65249112686 scopus 로고    scopus 로고
    • Perfusion scanning using 99mTc-HMPAO detects early cerebrovascular changes in the diabetic rat
    • Al-Saeedi FJ. Perfusion scanning using 99mTc-HMPAO detects early cerebrovascular changes in the diabetic rat. BMC Med Phys 2008; 8: 1.
    • (2008) BMC Med Phys , vol.8 , pp. 1
    • Al-Saeedi, F.J.1
  • 95
    • 0025165484 scopus 로고
    • A comparison of cerebral blood flow during basal, hypotensive, hypoxic and hypercapnic conditions between normal and streptozotocin diabetic rats
    • Simpson RE III, Phillis JW and Buchannan J. A comparison of cerebral blood flow during basal, hypotensive, hypoxic and hypercapnic conditions between normal and streptozotocin diabetic rats. Brain Res 1990; 531: 136-142.
    • (1990) Brain Res , vol.531 , pp. 136-142
    • Simpson, R.E.1    Phillis, J.W.2    Buchannan, J.3
  • 96
    • 0022356609 scopus 로고
    • Cerebral vascular autoregulation of blood flow and tissue PO2 in diabetic rats
    • Rubin MJ and Bohlen HG. Cerebral vascular autoregulation of blood flow and tissue PO2 in diabetic rats. Am J Physiol 1985; 249: H540-H546.
    • (1985) Am J Physiol , vol.249 , pp. H540-H546
    • Rubin, M.J.1    Bohlen, H.G.2
  • 97
    • 84896723621 scopus 로고    scopus 로고
    • Regional cerebral blood flow and arterial blood volume and their reactivity to hypercapnia in hypertensive and normotensive rats
    • Kim T, Richard Jennings J and Kim SG. Regional cerebral blood flow and arterial blood volume and their reactivity to hypercapnia in hypertensive and normotensive rats. J Cereb Blood Flow Metab 2014; 34: 408-414.
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 408-414
    • Kim, T.1    Richard Jennings, J.2    Kim, S.G.3
  • 98
    • 77957272826 scopus 로고    scopus 로고
    • Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-Associated subtype of sporadic Alzheimer?s disease
    • Thal DR, Papassotiropoulos A, Saido TC, et al. Capillary cerebral amyloid angiopathy identifies a distinct APOE epsilon4-Associated subtype of sporadic Alzheimer?s disease. Acta Neuropathol 2010; 120: 169-183.
    • (2010) Acta Neuropathol , vol.120 , pp. 169-183
    • Thal, D.R.1    Papassotiropoulos, A.2    Saido, T.C.3
  • 99
    • 0141797311 scopus 로고    scopus 로고
    • APOE genotype and cerebral blood flow in healthy young individuals
    • Scarmeas N, Habeck CG, Stern Y, et al. APOE genotype and cerebral blood flow in healthy young individuals. JAMA 2003; 290: 1581-1582.
    • (2003) JAMA , vol.290 , pp. 1581-1582
    • Scarmeas, N.1    Habeck, C.G.2    Stern, Y.3
  • 100
    • 25444522210 scopus 로고    scopus 로고
    • APOE related alterations in cerebral activation even at college age
    • Scarmeas N, Habeck CG, Hilton J, et al. APOE related alterations in cerebral activation even at college age. J Neurol Neurosurg Psychiatry 2005; 76: 1440-1444.
    • (2005) J Neurol Neurosurg Psychiatry , vol.76 , pp. 1440-1444
    • Scarmeas, N.1    Habeck, C.G.2    Hilton, J.3
  • 101
    • 0034680078 scopus 로고    scopus 로고
    • Patterns of brain activation in people at risk for Alzheimer?s disease
    • Bookheimer SY, Strojwas MH, Cohen MS, et al. Patterns of brain activation in people at risk for Alzheimer?s disease. N Engl J Med 2000; 343: 450-456.
    • (2000) N Engl J Med , vol.343 , pp. 450-456
    • Bookheimer, S.Y.1    Strojwas, M.H.2    Cohen, M.S.3
  • 102
    • 66349129276 scopus 로고    scopus 로고
    • Distinct patterns of brain activity in young carriers of the APOEepsilon4 allele
    • Filippini N, MacIntosh BJ, Hough MG, et al. Distinct patterns of brain activity in young carriers of the APOEepsilon4 allele. Proc Natl Acad Sci U S A 2009; 106: 7209-7214.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 7209-7214
    • Filippini, N.1    MacIntosh, B.J.2    Hough, M.G.3
  • 103
    • 28944444529 scopus 로고    scopus 로고
    • Identification of Alzheimer disease risk by functional magnetic resonance imaging
    • Fleisher AS, Houston WS, Eyler LT, et al. Identification of Alzheimer disease risk by functional magnetic resonance imaging. Arch Neurol 2005; 62: 1881-1888.
    • (2005) Arch Neurol , vol.62 , pp. 1881-1888
    • Fleisher, A.S.1    Houston, W.S.2    Eyler, L.T.3
  • 104
    • 37149025937 scopus 로고    scopus 로고
    • Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: A pilot study
    • DiFrancesco MW, Holland SK, Ris MD, et al. Functional magnetic resonance imaging assessment of cognitive function in childhood-onset systemic lupus erythematosus: a pilot study. Arthritis Rheum 2007; 56: 4151-4163.
    • (2007) Arthritis Rheum , vol.56 , pp. 4151-4163
    • DiFrancesco, M.W.1    Holland, S.K.2    Ris, M.D.3
  • 105
    • 0037069298 scopus 로고    scopus 로고
    • Abnormal brain activation on functional MRI in cognitively asymptomatic HIV patients
    • Ernst T, Chang L, Jovicich J, et al. Abnormal brain activation on functional MRI in cognitively asymptomatic HIV patients. Neurology 2002; 59: 1343-1349.
    • (2002) Neurology , vol.59 , pp. 1343-1349
    • Ernst, T.1    Chang, L.2    Jovicich, J.3
  • 106
    • 0042925731 scopus 로고    scopus 로고
    • Increased glial metabolites predict increased working memory network activation in HIV brain injury
    • Ernst T, Chang L and Arnold S. Increased glial metabolites predict increased working memory network activation in HIV brain injury. Neuroimage 2003; 19: 1686-1693.
    • (2003) Neuroimage , vol.19 , pp. 1686-1693
    • Ernst, T.1    Chang, L.2    Arnold, S.3
  • 107
    • 57049170731 scopus 로고    scopus 로고
    • Combination antiretroviral therapy modulates the blood oxygen level-Dependent amplitude in human immunodeficiency virus-seropositive patients
    • Ances BM, Roc AC, Korczykowski M, et al. Combination antiretroviral therapy modulates the blood oxygen level-Dependent amplitude in human immunodeficiency virus-seropositive patients. J Neurovirol 2008; 14: 418-424.
    • (2008) J Neurovirol , vol.14 , pp. 418-424
    • Ances, B.M.1    Roc, A.C.2    Korczykowski, M.3
  • 108
    • 84862990555 scopus 로고    scopus 로고
    • Dynamic models of BOLD contrast
    • Buxton RB. Dynamic models of BOLD contrast. Neuroimage 2012; 62: 953-961.
    • (2012) Neuroimage , vol.62 , pp. 953-961
    • Buxton, R.B.1
  • 109
    • 74949100133 scopus 로고    scopus 로고
    • APOE epsilon4 genotype and longitudinal changes in cerebral blood flow in normal aging
    • Thambisetty M, Beason-Held L, An Y, et al. APOE epsilon4 genotype and longitudinal changes in cerebral blood flow in normal aging. Arch Neurol 2010; 67: 93-98.
    • (2010) Arch Neurol , vol.67 , pp. 93-98
    • Thambisetty, M.1    Beason-Held, L.2    An, Y.3
  • 110
    • 70149105133 scopus 로고    scopus 로고
    • Cerebral perfusion and oxygenation differences in Alzheimer?s disease risk
    • Fleisher AS, Podraza KM, Bangen KJ, et al. Cerebral perfusion and oxygenation differences in Alzheimer?s disease risk. Neurobiol Aging 2009; 30: 1737-1748.
    • (2009) Neurobiol Aging , vol.30 , pp. 1737-1748
    • Fleisher, A.S.1    Podraza, K.M.2    Bangen, K.J.3
  • 111
    • 84879952423 scopus 로고    scopus 로고
    • Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension
    • Calcinaghi N, Wyss MT, Jolivet R, et al. Multimodal imaging in rats reveals impaired neurovascular coupling in sustained hypertension. Stroke 2013; 44: 1957-1964.
    • (2013) Stroke , vol.44 , pp. 1957-1964
    • Calcinaghi, N.1    Wyss, M.T.2    Jolivet, R.3
  • 112
    • 84931036843 scopus 로고    scopus 로고
    • Reduced cerebrovascular reactivity in young adults carrying the APOE epsilon4 allele
    • Suri S, Mackay CE, Kelly ME, et al. Reduced cerebrovascular reactivity in young adults carrying the APOE epsilon4 allele. Alzheimers Dement 2015; 11: 648-657.
    • (2015) Alzheimers Dement , vol.11 , pp. 648-657
    • Suri, S.1    Mackay, C.E.2    Kelly, M.E.3
  • 113
    • 33644649803 scopus 로고    scopus 로고
    • Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease
    • Girouard H and Iadecola C. Neurovascular coupling in the normal brain and in hypertension, stroke, and Alzheimer disease. J Appl Physiol 2006; 100: 328-335.
    • (2006) J Appl Physiol , vol.100 , pp. 328-335
    • Girouard, H.1    Iadecola, C.2
  • 114
    • 0142170002 scopus 로고    scopus 로고
    • Angiotensin II attenuates functional hyperemia in the mouse somatosensory cortex
    • Kazama K, Wang G, Frys K, et al. Angiotensin II attenuates functional hyperemia in the mouse somatosensory cortex. Am J Physiol Heart Circ Physiol 2003; 285: H1890-H1899.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H1890-H1899
    • Kazama, K.1    Wang, G.2    Frys, K.3
  • 115
    • 0034662501 scopus 로고    scopus 로고
    • Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation
    • Niwa K, Younkin L, Ebeling C, et al. Abeta 1-40-related reduction in functional hyperemia in mouse neocortex during somatosensory activation. Proc Natl Acad Sci U S A 2000; 97: 9735-9740.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 9735-9740
    • Niwa, K.1    Younkin, L.2    Ebeling, C.3
  • 116
    • 78651313012 scopus 로고    scopus 로고
    • The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension
    • Capone C, Faraco G, Park L, et al. The cerebrovascular dysfunction induced by slow pressor doses of angiotensin II precedes the development of hypertension. Am J Physiol Heart Circ Physiol 2011; 300: H397-H407.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H397-H407
    • Capone, C.1    Faraco, G.2    Park, L.3
  • 117
    • 8844227341 scopus 로고    scopus 로고
    • Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-Derived radicals
    • Kazama K, Anrather J, Zhou P, et al. Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-Derived radicals. Circ Res 2004; 95: 1019-1026.
    • (2004) Circ Res , vol.95 , pp. 1019-1026
    • Kazama, K.1    Anrather, J.2    Zhou, P.3
  • 118
    • 33846447793 scopus 로고    scopus 로고
    • Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II
    • Girouard H, Park L, Anrather J, et al. Cerebrovascular nitrosative stress mediates neurovascular and endothelial dysfunction induced by angiotensin II. Arterioscler Thromb Vasc Biol 2007; 27: 303-309.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 303-309
    • Girouard, H.1    Park, L.2    Anrather, J.3
  • 120
    • 33846863589 scopus 로고    scopus 로고
    • Nitric oxide and peroxynitrite in health and disease
    • Pacher P, Beckman JS and Liaudet L. Nitric oxide and peroxynitrite in health and disease. Physiol Rev 2007; 87: 315-424.
    • (2007) Physiol Rev , vol.87 , pp. 315-424
    • Pacher, P.1    Beckman, J.S.2    Liaudet, L.3
  • 121
    • 8644277006 scopus 로고    scopus 로고
    • Reactive oxygen species in vascular biology: Implications in hypertension
    • Touyz RM and Schiffrin EL. Reactive oxygen species in vascular biology: implications in hypertension. Histochem Cell Biol 2004; 122: 339-352.
    • (2004) Histochem Cell Biol , vol.122 , pp. 339-352
    • Touyz, R.M.1    Schiffrin, E.L.2
  • 122
    • 84923265935 scopus 로고    scopus 로고
    • Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue
    • Sakadzic S, Mandeville ET, Gagnon L, et al. Large arteriolar component of oxygen delivery implies a safe margin of oxygen supply to cerebral tissue. Nat Commun 2014; 5: 5734.
    • (2014) Nat Commun , vol.5 , pp. 5734
    • Sakadzic, S.1    Mandeville, E.T.2    Gagnon, L.3
  • 123
    • 0030700386 scopus 로고    scopus 로고
    • Cerebral microvascular alterations in aging, leukoaraiosis, and Alzheimer?s disease
    • Moody DM, Brown WR, Challa VR, et al. Cerebral microvascular alterations in aging, leukoaraiosis, and Alzheimer?s disease. Ann N Y Acad Sci 1997; 826: 103-116.
    • (1997) Ann N y Acad Sci , vol.826 , pp. 103-116
    • Moody, D.M.1    Brown, W.R.2    Challa, V.R.3
  • 124
    • 66149148718 scopus 로고    scopus 로고
    • Differences in retinal vessels support a distinct vasculopathy causing lacunar stroke
    • Doubal FN, MacGillivray TJ, Hokke PE, et al. Differences in retinal vessels support a distinct vasculopathy causing lacunar stroke. Neurology 2009; 72: 1773-1778.
    • (2009) Neurology , vol.72 , pp. 1773-1778
    • Doubal, F.N.1    MacGillivray, T.J.2    Hokke, P.E.3
  • 125
    • 67649413147 scopus 로고    scopus 로고
    • Retinal microvasculature in acute lacunar stroke: A cross-sectional study
    • Lindley RI, Wang JJ, Wong MC, et al. Retinal microvasculature in acute lacunar stroke: a cross-sectional study. Lancet Neurol 2009; 8: 628-634.
    • (2009) Lancet Neurol , vol.8 , pp. 628-634
    • Lindley, R.I.1    Wang, J.J.2    Wong, M.C.3
  • 126
    • 18244397953 scopus 로고    scopus 로고
    • Elevated cerebral blood flow velocities in Fabry disease with reversal after enzyme replacement
    • Moore DF, Altarescu G, Ling GS, et al. Elevated cerebral blood flow velocities in Fabry disease with reversal after enzyme replacement. Stroke 2002; 33: 525-531.
    • (2002) Stroke , vol.33 , pp. 525-531
    • Moore, D.F.1    Altarescu, G.2    Ling, G.S.3
  • 127
    • 0035949721 scopus 로고    scopus 로고
    • Regional cerebral hyperperfusion and nitric oxide pathway dysregulation in Fabry disease: Reversal by enzyme replacement therapy
    • Moore DF, Scott LT, Gladwin MT, et al. Regional cerebral hyperperfusion and nitric oxide pathway dysregulation in Fabry disease: reversal by enzyme replacement therapy. Circulation 2001; 104: 1506-1512.
    • (2001) Circulation , vol.104 , pp. 1506-1512
    • Moore, D.F.1    Scott, L.T.2    Gladwin, M.T.3
  • 128
    • 0034935252 scopus 로고    scopus 로고
    • Selective arterial distribution of cerebral hyperperfusion in Fabry disease
    • Moore DF, Herscovitch P and Schiffmann R. Selective arterial distribution of cerebral hyperperfusion in Fabry disease. J Neuroimaging 2001; 11: 303-307.
    • (2001) J Neuroimaging , vol.11 , pp. 303-307
    • Moore, D.F.1    Herscovitch, P.2    Schiffmann, R.3
  • 129
    • 0347123263 scopus 로고    scopus 로고
    • White matter lesions in Fabry disease occur in 'prior' selectively hypometabolic and hyperperfused brain regions
    • Moore DF, Altarescu G, Barker WC, et al. White matter lesions in Fabry disease occur in 'prior' selectively hypometabolic and hyperperfused brain regions. Brain Res Bull 2003; 62: 231-240.
    • (2003) Brain Res Bull , vol.62 , pp. 231-240
    • Moore, D.F.1    Altarescu, G.2    Barker, W.C.3
  • 130
    • 0028882549 scopus 로고
    • Cerebral metabolism of oxygen and glucose in a patient with MELAS syndrome
    • Sano M, Ishii K, Momose Y, et al. Cerebral metabolism of oxygen and glucose in a patient with MELAS syndrome. Acta Neurol Scand 1995; 92: 497-502.
    • (1995) Acta Neurol Scand , vol.92 , pp. 497-502
    • Sano, M.1    Ishii, K.2    Momose, Y.3
  • 131
    • 0032507974 scopus 로고    scopus 로고
    • Cerebral blood flow and oxygen metabolism before and after a stroke-like episode in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes (MELAS)
    • Takahashi S, Tohgi H, Yonezawa H, et al. Cerebral blood flow and oxygen metabolism before and after a stroke-like episode in patients with mitochondrial myopathy, encephalopathy, lactic acidosis and strokelike episodes (MELAS). J Neurol Sci 1998; 158: 58-64.
    • (1998) J Neurol Sci , vol.158 , pp. 58-64
    • Takahashi, S.1    Tohgi, H.2    Yonezawa, H.3
  • 132
    • 84867876753 scopus 로고    scopus 로고
    • MR evaluation of cerebral oxygen metabolism and blood flow in stroke-like episodes of MELAS
    • Wang Z, Xiao J, Xie S, et al. MR evaluation of cerebral oxygen metabolism and blood flow in stroke-like episodes of MELAS. J Neurol Sci 2012; 323: 173-177.
    • (2012) J Neurol Sci , vol.323 , pp. 173-177
    • Wang, Z.1    Xiao, J.2    Xie, S.3
  • 133
    • 84892552993 scopus 로고    scopus 로고
    • Quantitative measurement of cerebral oxygen extraction fraction using MRI in patients with MELAS
    • Yu L, Xie S, Xiao J, et al. Quantitative measurement of cerebral oxygen extraction fraction using MRI in patients with MELAS. PLoS One 2013; 8: e79859.
    • (2013) PLoS One , vol.8 , pp. e79859
    • Yu, L.1    Xie, S.2    Xiao, J.3
  • 135
    • 0034859487 scopus 로고    scopus 로고
    • Focal hyperperfusion in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes Case report
    • Amagasaki K, Shimizu T, Suzuki Y, et al. Focal hyperperfusion in a patient with mitochondrial myopathy, encephalopathy, lactic acidosis, and strokelike episodes. Case report. J Neurosurg 2001; 94: 133-136.
    • (2001) J Neurosurg , vol.94 , pp. 133-136
    • Amagasaki, K.1    Shimizu, T.2    Suzuki, Y.3
  • 136
    • 84885062646 scopus 로고    scopus 로고
    • Whole brain radiation-induced vascular cognitive impairment: Mechanisms and implications
    • Warrington JP, Ashpole N, Csiszar A, et al. Whole brain radiation-induced vascular cognitive impairment: mechanisms and implications. J Vasc Res 2013; 50: 445-457.
    • (2013) J Vasc Res , vol.50 , pp. 445-457
    • Warrington, J.P.1    Ashpole, N.2    Csiszar, A.3
  • 137
    • 79955051491 scopus 로고    scopus 로고
    • Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice
    • Warrington JP, Csiszar A, Johnson DA, et al. Cerebral microvascular rarefaction induced by whole brain radiation is reversible by systemic hypoxia in mice. Am J Physiol Heart Circ Physiol 2011; 300: H736-H744.
    • (2011) Am J Physiol Heart Circ Physiol , vol.300 , pp. H736-H744
    • Warrington, J.P.1    Csiszar, A.2    Johnson, D.A.3
  • 138
    • 0023794844 scopus 로고
    • Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy
    • Mineura K, Suda Y, Yasuda T, et al. Early and late stage positron emission tomography (PET) studies on the haemocirculation and metabolism of seemingly normal brain tissue in patients with gliomas following radiochemotherapy. Acta Neurochir (Wien) 1988; 93: 110-115.
    • (1988) Acta Neurochir (Wien) , vol.93 , pp. 110-115
    • Mineura, K.1    Suda, Y.2    Yasuda, T.3
  • 139
    • 61349118006 scopus 로고    scopus 로고
    • Dose-Dependent effects of radiation therapy on cerebral blood flow, metabolism, and neurocognitive dysfunction
    • Hahn CA, Zhou SM, Raynor R, et al. Dose-Dependent effects of radiation therapy on cerebral blood flow, metabolism, and neurocognitive dysfunction. Int J Radiat Oncol Biol Phys 2009; 73: 1082-1087.
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 1082-1087
    • Hahn, C.A.1    Zhou, S.M.2    Raynor, R.3
  • 140
    • 84929119501 scopus 로고    scopus 로고
    • Capillary dysfunction: Its detection and causative role in dementias and stroke
    • Ostergaard L, Jespersen SN, Engedal TS, et al. Capillary dysfunction: its detection and causative role in dementias and stroke. Curr Neurol Neurosci Rep 2015; 15: 557.
    • (2015) Curr Neurol Neurosci Rep , vol.15 , pp. 557
    • Ostergaard, L.1    Jespersen, S.N.2    Engedal, T.S.3
  • 141
    • 0033582130 scopus 로고    scopus 로고
    • Changes in regional cerebral blood flow after a cold hand test in systemic lupus erythematosus patients with Raynaud?s syndrome
    • Ferraccioli G, Di Poi E, Di Gregorio F, et al. Changes in regional cerebral blood flow after a cold hand test in systemic lupus erythematosus patients with Raynaud?s syndrome. Lancet 1999; 354: 2135-2136.
    • (1999) Lancet , vol.354 , pp. 2135-2136
    • Ferraccioli, G.1    Di Poi, E.2    Di Gregorio, F.3
  • 143
    • 1442348272 scopus 로고    scopus 로고
    • Endothelial nitric oxide gene haplotypes and risk of cerebral smallvessel disease
    • Hassan A, Gormley K, O?Sullivan M, et al. Endothelial nitric oxide gene haplotypes and risk of cerebral smallvessel disease. Stroke 2004; 35: 654-659.
    • (2004) Stroke , vol.35 , pp. 654-659
    • Hassan, A.1    Gormley, K.2    O'Sullivan, M.3
  • 144
    • 61849109765 scopus 로고    scopus 로고
    • Protective role of 27bp repeat polymorphism in intron 4 of eNOS gene in lacunar infarction
    • Yemisci M, Sinici I, Ozkara HA, et al. Protective role of 27bp repeat polymorphism in intron 4 of eNOS gene in lacunar infarction. Free Radic Res 2009; 43: 272-279.
    • (2009) Free Radic Res , vol.43 , pp. 272-279
    • Yemisci, M.1    Sinici, I.2    Ozkara, H.A.3
  • 145
    • 67650715561 scopus 로고    scopus 로고
    • Nitrite as regulator of hypoxic signaling in mammalian physiology
    • van Faassen EE, Bahrami S, Feelisch M, et al. Nitrite as regulator of hypoxic signaling in mammalian physiology. Med Res Rev 2009; 29: 683-741.
    • (2009) Med Res Rev , vol.29 , pp. 683-741
    • Van Faassen, E.E.1    Bahrami, S.2    Feelisch, M.3
  • 146
    • 84880934609 scopus 로고    scopus 로고
    • A NO way to BOLD? Dietary nitrate alters the hemodynamic response to visual stimulation
    • Aamand R, Dalsgaard T, Ho YC, et al. A NO way to BOLD?. Dietary nitrate alters the hemodynamic response to visual stimulation. Neuroimage 2013; 83: 397-407.
    • (2013) Neuroimage , vol.83 , pp. 397-407
    • Aamand, R.1    Dalsgaard, T.2    Ho, Y.C.3
  • 147
    • 67649812056 scopus 로고
    • Cerebral blood flow and oxygen consumption in neurosyphilis
    • Patterson JL Jr, Heyman A and Nichols Jr. F.T. Cerebral blood flow and oxygen consumption in neurosyphilis. J Clin Invest 1950; 29: 1327-1334.
    • (1950) J Clin Invest , vol.29 , pp. 1327-1334
    • Patterson, J.L.1    Heyman, A.2    Nichols, F.T.3
  • 148
    • 0031470270 scopus 로고    scopus 로고
    • Reversible cerebral hypoperfusion in Lyme encephalopathy
    • Logigian EL, Johnson KA, Kijewski MF, et al. Reversible cerebral hypoperfusion in Lyme encephalopathy. Neurology 1997; 49: 1661-1670.
    • (1997) Neurology , vol.49 , pp. 1661-1670
    • Logigian, E.L.1    Johnson, K.A.2    Kijewski, M.F.3
  • 150
    • 0003958724 scopus 로고
    • Alterations of cerebral capillaries in the early stage of arterial hypertension
    • Scheinker IM. Alterations of cerebral capillaries in the early stage of arterial hypertension. Am J Pathol 1948; 24: 211-221.
    • (1948) Am J Pathol , vol.24 , pp. 211-221
    • Scheinker, I.M.1
  • 151
    • 84874948266 scopus 로고    scopus 로고
    • Antihypertensive treatment can prevent stroke and cognitive decline
    • Soros P, Whitehead S, Spence JD, et al. Antihypertensive treatment can prevent stroke and cognitive decline. Nat Rev Neurol 2013; 9: 174-178.
    • (2013) Nat Rev Neurol , vol.9 , pp. 174-178
    • Soros, P.1    Whitehead, S.2    Spence, J.D.3
  • 152
    • 0025057936 scopus 로고
    • Kinetic analysis of blood-brain barrier transport of D-glucose in man: Quantitative evaluation in the presence of tracer backflux and capillary heterogeneity
    • Knudsen GM, Pettigrew KD, Paulson OB, et al. Kinetic analysis of blood-brain barrier transport of D-glucose in man: quantitative evaluation in the presence of tracer backflux and capillary heterogeneity. Microvasc Res 1990; 39: 28-49.
    • (1990) Microvasc Res , vol.39 , pp. 28-49
    • Knudsen, G.M.1    Pettigrew, K.D.2    Paulson, O.B.3
  • 153
    • 34547624611 scopus 로고    scopus 로고
    • Supply and demand in cerebral energy metabolism: The role of nutrient transporters
    • Simpson IA, Carruthers A and Vannucci SJ. Supply and demand in cerebral energy metabolism: the role of nutrient transporters. J Cereb Blood Flow Metab 2007; 27: 1766-1791.
    • (2007) J Cereb Blood Flow Metab , vol.27 , pp. 1766-1791
    • Simpson, I.A.1    Carruthers, A.2    Vannucci, S.J.3
  • 154
    • 28444463228 scopus 로고    scopus 로고
    • Principles of cerebral perfusion imaging by bolus tracking
    • Ostergaard L. Principles of cerebral perfusion imaging by bolus tracking. J Magn Reson Imaging 2005; 22: 710-717.
    • (2005) J Magn Reson Imaging , vol.22 , pp. 710-717
    • Ostergaard, L.1
  • 155
    • 77952608748 scopus 로고    scopus 로고
    • Defects in oxygen supply to skeletal muscle of prediabetic ZDF rats
    • Ellis CG, Goldman D, Hanson M, et al. Defects in oxygen supply to skeletal muscle of prediabetic ZDF rats. Am J Physiol Heart Circ Physiol 2010; 298: H1661-H1670.
    • (2010) Am J Physiol Heart Circ Physiol , vol.298 , pp. H1661-H1670
    • Ellis, C.G.1    Goldman, D.2    Hanson, M.3
  • 156
    • 84902549150 scopus 로고    scopus 로고
    • Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: One-year randomized, clinical trial
    • Domenech M, Roman P, Lapetra J, et al. Mediterranean diet reduces 24-hour ambulatory blood pressure, blood glucose, and lipids: one-year randomized, clinical trial. Hypertension 2014; 64: 69-76.
    • (2014) Hypertension , vol.64 , pp. 69-76
    • Domenech, M.1    Roman, P.2    Lapetra, J.3
  • 157
    • 84884755163 scopus 로고    scopus 로고
    • The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis
    • Ostergaard L, Tietze A, Nielsen T, et al. The relationship between tumor blood flow, angiogenesis, tumor hypoxia, and aerobic glycolysis. Cancer Res 2013; 73: 5618-5624.
    • (2013) Cancer Res , vol.73 , pp. 5618-5624
    • Ostergaard, L.1    Tietze, A.2    Nielsen, T.3
  • 158
    • 0036165239 scopus 로고    scopus 로고
    • Association between influenza vaccination and reduced risk of brain infarction
    • Lavallee P, Perchaud V, Gautier-Bertrand M, et al. Association between influenza vaccination and reduced risk of brain infarction. Stroke 2002; 33: 513-518.
    • (2002) Stroke , vol.33 , pp. 513-518
    • Lavallee, P.1    Perchaud, V.2    Gautier-Bertrand, M.3
  • 159
    • 0037417219 scopus 로고    scopus 로고
    • Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly
    • Nichol KL, Nordin J, Mullooly J, et al. Influenza vaccination and reduction in hospitalizations for cardiac disease and stroke among the elderly. N Engl J Med 2003; 348: 1322-1332.
    • (2003) N Engl J Med , vol.348 , pp. 1322-1332
    • Nichol, K.L.1    Nordin, J.2    Mullooly, J.3
  • 160
    • 22044447049 scopus 로고    scopus 로고
    • Influenza vaccination is associated with a reduced risk of stroke
    • Grau AJ, Fischer B, Barth C, et al. Influenza vaccination is associated with a reduced risk of stroke. Stroke 2005; 36: 1501-1506.
    • (2005) Stroke , vol.36 , pp. 1501-1506
    • Grau, A.J.1    Fischer, B.2    Barth, C.3
  • 161
    • 67349144455 scopus 로고    scopus 로고
    • Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer?s disease
    • Kountouras J, Boziki M, Gavalas E, et al. Eradication of Helicobacter pylori may be beneficial in the management of Alzheimer?s disease. J Neurol 2009; 256: 758-767.
    • (2009) J Neurol , vol.256 , pp. 758-767
    • Kountouras, J.1    Boziki, M.2    Gavalas, E.3
  • 162
    • 77957586832 scopus 로고    scopus 로고
    • Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients
    • Kountouras J, Boziki M, Gavalas E, et al. Five-year survival after Helicobacter pylori eradication in Alzheimer disease patients. Cogn Behav Neurol 2010; 23: 199-204.
    • (2010) Cogn Behav Neurol , vol.23 , pp. 199-204
    • Kountouras, J.1    Boziki, M.2    Gavalas, E.3
  • 163
    • 0033538267 scopus 로고    scopus 로고
    • Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins
    • Nappo F, De Rosa N, Marfella R, et al. Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins. JAMA 1999; 281: 2113-2118.
    • (1999) JAMA , vol.281 , pp. 2113-2118
    • Nappo, F.1    De Rosa, N.2    Marfella, R.3
  • 164
    • 0346097879 scopus 로고    scopus 로고
    • Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction
    • Hassan A, Hunt BJ, O?Sullivan M, et al. Homocysteine is a risk factor for cerebral small vessel disease, acting via endothelial dysfunction. Brain 2004; 127: 212-219.
    • (2004) Brain , vol.127 , pp. 212-219
    • Hassan, A.1    Hunt, B.J.2    O'Sullivan, M.3
  • 165
    • 80051695692 scopus 로고    scopus 로고
    • Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: A meta-Analysis of genetic studies and randomised trials
    • Holmes MV, Newcombe P, Hubacek JA, et al. Effect modification by population dietary folate on the association between MTHFR genotype, homocysteine, and stroke risk: a meta-Analysis of genetic studies and randomised trials. Lancet 2011; 378: 584-594.
    • (2011) Lancet , vol.378 , pp. 584-594
    • Holmes, M.V.1    Newcombe, P.2    Hubacek, J.A.3
  • 166
    • 0014749468 scopus 로고
    • Inhibition of 3050-cyclic-AMP phosphodiesterase by some platelet aggregation inhibitors
    • Horlington M and Watson PA. Inhibition of 3050-cyclic-AMP phosphodiesterase by some platelet aggregation inhibitors. Biochem Pharmacol 1970; 19: 955-956.
    • (1970) Biochem Pharmacol , vol.19 , pp. 955-956
    • Horlington, M.1    Watson, P.A.2
  • 167
    • 4344685960 scopus 로고    scopus 로고
    • Drug treatment of intermittent claudication
    • Jacoby D and Mohler ER III. Drug treatment of intermittent claudication. Drugs 2004; 64: 1657-1670.
    • (2004) Drugs , vol.64 , pp. 1657-1670
    • Jacoby, D.1    Mohler, E.R.2
  • 168
    • 84929519122 scopus 로고    scopus 로고
    • Pharmacological treatment and prevention of cerebral small vessel disease: A review of potential interventions
    • Bath PM and Wardlaw JM. Pharmacological treatment and prevention of cerebral small vessel disease: a review of potential interventions. Int J Stroke 2015; 10: 469-478.
    • (2015) Int J Stroke , vol.10 , pp. 469-478
    • Bath, P.M.1    Wardlaw, J.M.2
  • 169
    • 2542462256 scopus 로고    scopus 로고
    • Nicotine induces mononuclear leukocyte adhesion and expression of adhesion molecules, VCAM and ICAM, in endothelial cells in vitro
    • Albaugh G, Bellavance E, Strande L, et al. Nicotine induces mononuclear leukocyte adhesion and expression of adhesion molecules, VCAM and ICAM, in endothelial cells in vitro. Ann Vasc Surg 2004; 18: 302-307.
    • (2004) Ann Vasc Surg , vol.18 , pp. 302-307
    • Albaugh, G.1    Bellavance, E.2    Strande, L.3
  • 170
    • 0344110498 scopus 로고    scopus 로고
    • Nicotine induces leukocyte rolling and adhesion in the cerebral microcirculation of the mouse
    • Yong T, Zheng MQ and Linthicum DS. Nicotine induces leukocyte rolling and adhesion in the cerebral microcirculation of the mouse. J Neuroimmunol 1997; 80: 158-164.
    • (1997) J Neuroimmunol , vol.80 , pp. 158-164
    • Yong, T.1    Zheng, M.Q.2    Linthicum, D.S.3
  • 171
    • 45549106551 scopus 로고    scopus 로고
    • The physiology of leukocyte recruitment: An in vivo perspective
    • Petri B, Phillipson M and Kubes P. The physiology of leukocyte recruitment: an in vivo perspective. J Immunol 2008; 180: 6439-6446.
    • (2008) J Immunol , vol.180 , pp. 6439-6446
    • Petri, B.1    Phillipson, M.2    Kubes, P.3
  • 172
    • 77950273952 scopus 로고    scopus 로고
    • Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: Study in 200 consecutively recruited individuals
    • Adib-Samii P, Brice G, Martin RJ, et al. Clinical spectrum of CADASIL and the effect of cardiovascular risk factors on phenotype: study in 200 consecutively recruited individuals. Stroke 2010; 41: 630-634.
    • (2010) Stroke , vol.41 , pp. 630-634
    • Adib-Samii, P.1    Brice, G.2    Martin, R.J.3
  • 173
    • 84920669309 scopus 로고    scopus 로고
    • Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden
    • Staals J, Makin SD, Doubal FN, et al. Stroke subtype, vascular risk factors, and total MRI brain small-vessel disease burden. Neurology 2014; 83: 1228-1234.
    • (2014) Neurology , vol.83 , pp. 1228-1234
    • Staals, J.1    Makin, S.D.2    Doubal, F.N.3
  • 174
    • 15244344823 scopus 로고    scopus 로고
    • Long-Term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: An observational study
    • Marin JM, Carrizo SJ, Vicente E, et al. Long-Term cardiovascular outcomes in men with obstructive sleep apnoea-hypopnoea with or without treatment with continuous positive airway pressure: an observational study. Lancet 2005; 365: 1046-1053.
    • (2005) Lancet , vol.365 , pp. 1046-1053
    • Marin, J.M.1    Carrizo, S.J.2    Vicente, E.3
  • 175
    • 84866404148 scopus 로고    scopus 로고
    • Delirium is a strong risk factor for dementia in the oldest-old: A population-based cohort study
    • Davis DH, Muniz Terrera G, Keage H, et al. Delirium is a strong risk factor for dementia in the oldest-old: a population-based cohort study. Brain 2012; 135: 2809-2816.
    • (2012) Brain , vol.135 , pp. 2809-2816
    • Davis, D.H.1    Muniz Terrera, G.2    Keage, H.3
  • 176
    • 84856908293 scopus 로고    scopus 로고
    • Mediterranean diet and white matter hyperintensity volume in the Northern Manhattan Study
    • Gardener H, Scarmeas N, Gu Y, et al. Mediterranean diet and white matter hyperintensity volume in the Northern Manhattan Study. Arch Neurol 2012; 69: 251-256.
    • (2012) Arch Neurol , vol.69 , pp. 251-256
    • Gardener, H.1    Scarmeas, N.2    Gu, Y.3
  • 177
    • 82455203956 scopus 로고    scopus 로고
    • Mediterraneanstyle diet and risk of ischemic stroke, myocardial infarction, and vascular death: The Northern Manhattan Study
    • Gardener H, Wright CB, Gu Y, et al. Mediterraneanstyle diet and risk of ischemic stroke, myocardial infarction, and vascular death: the Northern Manhattan Study. Am J Clin Nutr 2011; 94: 1458-1464.
    • (2011) Am J Clin Nutr , vol.94 , pp. 1458-1464
    • Gardener, H.1    Wright, C.B.2    Gu, Y.3
  • 178
    • 84875787136 scopus 로고    scopus 로고
    • Primary prevention of cardiovascular disease with a Mediterranean diet
    • Estruch R, Ros E, Salas-Salvado J, et al. Primary prevention of cardiovascular disease with a Mediterranean diet. N Engl J Med 2013; 368: 1279-1290.
    • (2013) N Engl J Med , vol.368 , pp. 1279-1290
    • Estruch, R.1    Ros, E.2    Salas-Salvado, J.3
  • 179
    • 84926155314 scopus 로고    scopus 로고
    • Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury
    • Gaudin A, Yemisci M, Eroglu H, et al. Squalenoyl adenosine nanoparticles provide neuroprotection after stroke and spinal cord injury. Nat Nanotechnol 2014; 9: 1054-1062.
    • (2014) Nat Nanotechnol , vol.9 , pp. 1054-1062
    • Gaudin, A.1    Yemisci, M.2    Eroglu, H.3
  • 180
    • 80755188166 scopus 로고    scopus 로고
    • Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: The Carotid Occlusion Surgery Study randomized trial
    • Powers WJ, Clarke WR, Grubb RL Jr, et al. Extracranial-intracranial bypass surgery for stroke prevention in hemodynamic cerebral ischemia: the Carotid Occlusion Surgery Study randomized trial. JAMA 2011; 306: 1983-1992.
    • (2011) JAMA , vol.306 , pp. 1983-1992
    • Powers, W.J.1    Clarke, W.R.2    Grubb, R.L.3
  • 181
    • 80052557320 scopus 로고    scopus 로고
    • Computed tomography and magnetic resonance perfusion imaging in ischemic stroke: Definitions and thresholds
    • Dani KA, Thomas RG, Chappell FM, et al. Computed tomography and magnetic resonance perfusion imaging in ischemic stroke: definitions and thresholds. Ann Neurol 2011; 70: 384-401.
    • (2011) Ann Neurol , vol.70 , pp. 384-401
    • Dani, K.A.1    Thomas, R.G.2    Chappell, F.M.3
  • 182
    • 84908274250 scopus 로고    scopus 로고
    • Reliable estimation of capillary transit time distributions using DSC-MRI
    • Mouridsen K, Hansen MB, Ostergaard L, et al. Reliable estimation of capillary transit time distributions using DSC-MRI. J Cereb Blood Flow Metab 2014; 34: 1511-1521.
    • (2014) J Cereb Blood Flow Metab , vol.34 , pp. 1511-1521
    • Mouridsen, K.1    Hansen, M.B.2    Ostergaard, L.3
  • 183
    • 78149255128 scopus 로고    scopus 로고
    • Low-Density lipoprotein receptor-related protein-1: A serial clearance homeostatic mechanism controlling Alzheimer?s amyloid beta-peptide elimination from the brain
    • Zlokovic BV, Deane R, Sagare AP, et al. Low-Density lipoprotein receptor-related protein-1: a serial clearance homeostatic mechanism controlling Alzheimer?s amyloid beta-peptide elimination from the brain. J Neurochem 2010; 115: 1077-1089.
    • (2010) J Neurochem , vol.115 , pp. 1077-1089
    • Zlokovic, B.V.1    Deane, R.2    Sagare, A.P.3
  • 184
    • 81555200043 scopus 로고    scopus 로고
    • Neurovascular pathways to neurodegeneration in Alzheimer?s disease and other disorders
    • Zlokovic BV. Neurovascular pathways to neurodegeneration in Alzheimer?s disease and other disorders. Nat Rev Neurosci 2011; 12: 723-738.
    • (2011) Nat Rev Neurosci , vol.12 , pp. 723-738
    • Zlokovic, B.V.1
  • 186
    • 70449108112 scopus 로고    scopus 로고
    • Activation of PKC-Delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy
    • Geraldes P, Hiraoka-Yamamoto J, Matsumoto M, et al. Activation of PKC-Delta and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy. Nat Med 2009; 15: 1298-1306.
    • (2009) Nat Med , vol.15 , pp. 1298-1306
    • Geraldes, P.1    Hiraoka-Yamamoto, J.2    Matsumoto, M.3
  • 187
    • 0024392325 scopus 로고
    • Local brain haemodynamics and oxygen metabolism in cerebrovascular disease Positron emission tomography
    • Sette G, Baron JC, Mazoyer B, et al. Local brain haemodynamics and oxygen metabolism in cerebrovascular disease. Positron emission tomography. Brain 1989; 112 (Pt 4): 931-951.
    • (1989) Brain , vol.112 , pp. 931-951
    • Sette, G.1    Baron, J.C.2    Mazoyer, B.3
  • 188
    • 33646169409 scopus 로고    scopus 로고
    • Age-related microvascular degeneration in the human cerebral periventricular white matter
    • Farkas E, de Vos RA, Donka G, et al. Age-related microvascular degeneration in the human cerebral periventricular white matter. Acta Neuropathol 2006; 111: 150-157.
    • (2006) Acta Neuropathol , vol.111 , pp. 150-157
    • Farkas, E.1    De Vos, R.A.2    Donka, G.3
  • 189
    • 0035097499 scopus 로고    scopus 로고
    • A phase 1/2 clinical trial of enzyme replacement in fabry disease: Pharmacokinetic, substrate clearance, and safety studies
    • Eng CM, Banikazemi M, Gordon RE, et al. A phase 1/2 clinical trial of enzyme replacement in fabry disease: pharmacokinetic, substrate clearance, and safety studies. Am J Hum Genet 2001; 68: 711-722.
    • (2001) Am J Hum Genet , vol.68 , pp. 711-722
    • Eng, C.M.1    Banikazemi, M.2    Gordon, R.E.3
  • 190
    • 0035047718 scopus 로고    scopus 로고
    • Cerebral microvascular pathology in aging and Alzheimer?s disease
    • Farkas E and Luiten PG. Cerebral microvascular pathology in aging and Alzheimer?s disease. Prog Neurobiol 2001; 64: 575-611.
    • (2001) Prog Neurobiol , vol.64 , pp. 575-611
    • Farkas, E.1    Luiten, P.G.2
  • 191
    • 0024343409 scopus 로고
    • Vascular involvement in mitochondrial myopathy
    • Sakuta R and Nonaka I. Vascular involvement in mitochondrial myopathy. Ann Neurol 1989; 25: 594-601.
    • (1989) Ann Neurol , vol.25 , pp. 594-601
    • Sakuta, R.1    Nonaka, I.2
  • 192
    • 0023270881 scopus 로고
    • Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy
    • Ohama E, Ohara S, Ikuta F, et al. Mitochondrial angiopathy in cerebral blood vessels of mitochondrial encephalomyopathy. Acta Neuropathol 1987; 74: 226-233.
    • (1987) Acta Neuropathol , vol.74 , pp. 226-233
    • Ohama, E.1    Ohara, S.2    Ikuta, F.3
  • 193
    • 0028321471 scopus 로고
    • Microscopic susceptibility variation and transverse relaxation: Theory and experiment
    • Weisskoff RM, Zuo CS, Boxerman JL, et al. Microscopic susceptibility variation and transverse relaxation: theory and experiment. Magn Reson Med 1994; 31: 601-610.
    • (1994) Magn Reson Med , vol.31 , pp. 601-610
    • Weisskoff, R.M.1    Zuo, C.S.2    Boxerman, J.L.3
  • 194
    • 0030452414 scopus 로고    scopus 로고
    • Cerebral vessels in ageing and Alzheimer?s disease
    • Kalaria RN. Cerebral vessels in ageing and Alzheimer?s disease. Pharmacol Ther 1996; 72: 193-214.
    • (1996) Pharmacol Ther , vol.72 , pp. 193-214
    • Kalaria, R.N.1
  • 195
    • 0019427882 scopus 로고
    • Morphometric comparison of hippocampal microvasculature in ageing and demented people: Diameters and densities
    • Bell MA and Ball MJ. Morphometric comparison of hippocampal microvasculature in ageing and demented people: diameters and densities. Acta Neuropathol 1981; 53: 299-318.
    • (1981) Acta Neuropathol , vol.53 , pp. 299-318
    • Bell, M.A.1    Ball, M.J.2
  • 196
    • 0021933130 scopus 로고
    • Basement membrane of hypothalamus and cortex capillaries from normotensive and spontaneously hypertensive rats with streptozotocin-induced diabetes
    • Junker U, Jaggi C, Bestetti G, et al. Basement membrane of hypothalamus and cortex capillaries from normotensive and spontaneously hypertensive rats with streptozotocin-induced diabetes. Acta Neuropathol 1985; 65: 202-208.
    • (1985) Acta Neuropathol , vol.65 , pp. 202-208
    • Junker, U.1    Jaggi, C.2    Bestetti, G.3
  • 197
    • 0025334021 scopus 로고
    • Ultrastructural changes in cerebral pericytes and astrocytes of strokeprone spontaneously hypertensive rats
    • Tagami M, Nara Y, Kubota A, et al. Ultrastructural changes in cerebral pericytes and astrocytes of strokeprone spontaneously hypertensive rats. Stroke 1990; 21: 1064-1071.
    • (1990) Stroke , vol.21 , pp. 1064-1071
    • Tagami, M.1    Nara, Y.2    Kubota, A.3
  • 198
    • 0020027766 scopus 로고
    • Thickened cerebral cortical capillary basement membranes in diabetics
    • Johnson PC, Brendel K and Meezan E. Thickened cerebral cortical capillary basement membranes in diabetics. Arch Pathol Lab Med 1982; 106: 214-217.
    • (1982) Arch Pathol Lab Med , vol.106 , pp. 214-217
    • Johnson, P.C.1    Brendel, K.2    Meezan, E.3
  • 199
  • 200
    • 0021404067 scopus 로고
    • In vivo and electron microscopic study of the development of cerebral diabetic microangiography
    • McCuskey PA and McCuskey RS. In vivo and electron microscopic study of the development of cerebral diabetic microangiography. Microcirc Endothelium Lymphatics 1984; 1: 221-244.
    • (1984) Microcirc Endothelium Lymphatics , vol.1 , pp. 221-244
    • McCuskey, P.A.1    McCuskey, R.S.2
  • 201
    • 84455185110 scopus 로고    scopus 로고
    • Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice
    • Price TO, Eranki V, Banks WA, et al. Topiramate treatment protects blood-brain barrier pericytes from hyperglycemia-induced oxidative damage in diabetic mice. Endocrinology 2012; 153: 362-372.
    • (2012) Endocrinology , vol.153 , pp. 362-372
    • Price, T.O.1    Eranki, V.2    Banks, W.A.3
  • 202
    • 84874442369 scopus 로고    scopus 로고
    • Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucoseinduced oxidative stress and apoptosis
    • Shah GN, Price TO, Banks WA, et al. Pharmacological inhibition of mitochondrial carbonic anhydrases protects mouse cerebral pericytes from high glucoseinduced oxidative stress and apoptosis. J Pharmacol Exp Ther 2013; 344: 637-645.
    • (2013) J Pharmacol Exp Ther , vol.344 , pp. 637-645
    • Shah, G.N.1    Price, T.O.2    Banks, W.A.3
  • 203
    • 33846631327 scopus 로고    scopus 로고
    • Hereditary multi-infarct dementia of the Swedish type is a novel disorder different from NOTCH3 causing CADASIL
    • Low WC, Junna M, Borjesson-Hanson A, et al. Hereditary multi-infarct dementia of the Swedish type is a novel disorder different from NOTCH3 causing CADASIL. Brain 2007; 130: 357-367.
    • (2007) Brain , vol.130 , pp. 357-367
    • Low, W.C.1    Junna, M.2    Borjesson-Hanson, A.3
  • 204
    • 65249114174 scopus 로고    scopus 로고
    • Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients
    • Tikka S, Mykkanen K, Ruchoux MM, et al. Congruence between NOTCH3 mutations and GOM in 131 CADASIL patients. Brain 2009; 132: 933-939.
    • (2009) Brain , vol.132 , pp. 933-939
    • Tikka, S.1    Mykkanen, K.2    Ruchoux, M.M.3
  • 205
    • 84876680267 scopus 로고    scopus 로고
    • Brain microvascular accumulation and distribution of the NOTCH3 ectodomain and granular osmiophilic material in CADASIL
    • Yamamoto Y, Craggs LJ, Watanabe A, et al. Brain microvascular accumulation and distribution of the NOTCH3 ectodomain and granular osmiophilic material in CADASIL. J Neuropathol Exp Neurol 2013; 72: 416-431.
    • (2013) J Neuropathol Exp Neurol , vol.72 , pp. 416-431
    • Yamamoto, Y.1    Craggs, L.J.2    Watanabe, A.3
  • 206
    • 0026566806 scopus 로고
    • Central nervous system changes in mitochondrial encephalomyopathy: Light and electron microscopic study
    • Mizukami K, Sasaki M, Suzuki T, et al. Central nervous system changes in mitochondrial encephalomyopathy: light and electron microscopic study. Acta Neuropathol 1992; 83: 449-452.
    • (1992) Acta Neuropathol , vol.83 , pp. 449-452
    • Mizukami, K.1    Sasaki, M.2    Suzuki, T.3
  • 207
    • 0027280496 scopus 로고
    • Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): Clinical, radiological, pathological, and genetic observations
    • Koo B, Becker LE, Chuang S, et al. Mitochondrial encephalomyopathy, lactic acidosis, stroke-like episodes (MELAS): clinical, radiological, pathological, and genetic observations. Ann Neurol 1993; 34: 25-32.
    • (1993) Ann Neurol , vol.34 , pp. 25-32
    • Koo, B.1    Becker, L.E.2    Chuang, S.3
  • 208
    • 0015141307 scopus 로고
    • The central nervous system in Fabry?s disease A clinical, pathological, and biochemical investigation
    • Lou HO and Reske-Nielsen E. the central nervous system in Fabry?s disease. A clinical, pathological, and biochemical investigation. Arch Neurol 1971; 25: 351-359.
    • (1971) Arch Neurol , vol.25 , pp. 351-359
    • Lou, H.O.1    Reske-Nielsen, E.2
  • 209
    • 0015610057 scopus 로고
    • The central nervous system in Fabry?s disease An ultrastructural study
    • Grunnet ML and Spilsbury PR. The central nervous system in Fabry?s disease. An ultrastructural study. Arch Neurol 1973; 28: 231-234.
    • (1973) Arch Neurol , vol.28 , pp. 231-234
    • Grunnet, M.L.1    Spilsbury, P.R.2
  • 210
    • 0035664785 scopus 로고    scopus 로고
    • Local and global cerebral blood flow and glucose utilization in the alpha-galactosidase A knockout mouse model of Fabry disease
    • Itoh Y, Esaki T, Cook M, et al. Local and global cerebral blood flow and glucose utilization in the alpha-galactosidase A knockout mouse model of Fabry disease. J Neurochem 2001; 79: 1217-1224.
    • (2001) J Neurochem , vol.79 , pp. 1217-1224
    • Itoh, Y.1    Esaki, T.2    Cook, M.3
  • 211
    • 0033546629 scopus 로고    scopus 로고
    • Cerebroretinal vasculopathy mimicking a brain tumor: A case of a rare hereditary syndrome
    • Weil S, Reifenberger G, Dudel C, et al. Cerebroretinal vasculopathy mimicking a brain tumor: a case of a rare hereditary syndrome. Neurology 1999; 53: 629-631.
    • (1999) Neurology , vol.53 , pp. 629-631
    • Weil, S.1    Reifenberger, G.2    Dudel, C.3
  • 212
    • 0034943172 scopus 로고    scopus 로고
    • Enhanced endothelium-Dependent vasodilation in Fabry disease
    • Altarescu G, Moore DF, Pursley R, et al. Enhanced endothelium-Dependent vasodilation in Fabry disease. Stroke 2001; 32: 1559-1562.
    • (2001) Stroke , vol.32 , pp. 1559-1562
    • Altarescu, G.1    Moore, D.F.2    Pursley, R.3
  • 213
    • 18644369123 scopus 로고    scopus 로고
    • Novel ophthalmological features in hereditary endotheliopathy with retinopathy, nephropathy and stroke syndrome
    • Cohn AC, Kotschet K, Veitch A, et al. Novel ophthalmological features in hereditary endotheliopathy with retinopathy, nephropathy and stroke syndrome. Clin Experiment Ophthalmol 2005; 33: 181-183.
    • (2005) Clin Experiment Ophthalmol , vol.33 , pp. 181-183
    • Cohn, A.C.1    Kotschet, K.2    Veitch, A.3
  • 214
    • 0030712287 scopus 로고    scopus 로고
    • Hereditary endotheliopathy with retinopathy, nephropathy, and stroke (HERNS)
    • Jen J, Cohen AH, Yue Q, et al. Hereditary endotheliopathy with retinopathy, nephropathy, and stroke (HERNS). Neurology 1997; 49: 1322-1330.
    • (1997) Neurology , vol.49 , pp. 1322-1330
    • Jen, J.1    Cohen, A.H.2    Yue, Q.3
  • 215
    • 33645498692 scopus 로고    scopus 로고
    • Role of COL4A1 in small-vessel disease and hemorrhagic stroke
    • Gould DB, Phalan FC, van Mil SE, et al. Role of COL4A1 in small-vessel disease and hemorrhagic stroke. N Engl J Med 2006; 354: 1489-1496.
    • (2006) N Engl J Med , vol.354 , pp. 1489-1496
    • Gould, D.B.1    Phalan, F.C.2    Van Mil, S.E.3
  • 216
    • 1842482987 scopus 로고    scopus 로고
    • Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development
    • Poschl E, Schlotzer-Schrehardt U, Brachvogel B, et al. Collagen IV is essential for basement membrane stability but dispensable for initiation of its assembly during early development. Development 2004; 131: 1619-1628.
    • (2004) Development , vol.131 , pp. 1619-1628
    • Poschl, E.1    Schlotzer-Schrehardt, U.2    Brachvogel, B.3
  • 217
    • 4444267368 scopus 로고    scopus 로고
    • Subcortical angiopathic encephalopathy in a German kindred suggests an autosomal dominant disorder distinct from CADASIL
    • Hagel C, Groden C, Niemeyer R, et al. Subcortical angiopathic encephalopathy in a German kindred suggests an autosomal dominant disorder distinct from CADASIL. Acta Neuropathol 2004; 108: 231-240.
    • (2004) Acta Neuropathol , vol.108 , pp. 231-240
    • Hagel, C.1    Groden, C.2    Niemeyer, R.3
  • 218
    • 84882266384 scopus 로고    scopus 로고
    • Quantitative vascular pathology and phenotyping familial and sporadic cerebral small vessel diseases
    • Craggs LJ, Hagel C, Kuhlenbaeumer G, et al. Quantitative vascular pathology and phenotyping familial and sporadic cerebral small vessel diseases. Brain Pathol 2013; 23: 547-557.
    • (2013) Brain Pathol , vol.23 , pp. 547-557
    • Craggs, L.J.1    Hagel, C.2    Kuhlenbaeumer, G.3
  • 219
    • 84865968858 scopus 로고    scopus 로고
    • Endothelium-neutrophil interactions in ANCA-Associated diseases
    • Halbwachs L and Lesavre P. Endothelium-neutrophil interactions in ANCA-Associated diseases. J Am Soc Nephrol 2012; 23: 1449-1461.
    • (2012) J Am Soc Nephrol , vol.23 , pp. 1449-1461
    • Halbwachs, L.1    Lesavre, P.2
  • 220
    • 84910134582 scopus 로고    scopus 로고
    • Primary angiitis of the central nervous system in adults and children
    • viii
    • Rodriguez-Pla A and Monach PA. Primary angiitis of the central nervous system in adults and children. Rheum Dis Clin North Am 2015; 41: 47-62, viii.
    • (2015) Rheum Dis Clin North Am , vol.41 , pp. 47-62
    • Rodriguez-Pla, A.1    Monach, P.A.2
  • 221
    • 76549172865 scopus 로고
    • Cerebro-vascular lesions and livedo reticularis
    • SNEDDON IB. Cerebro-vascular lesions and livedo reticularis. Br J Dermatol 1965; 77: 180-185.
    • (1965) Br J Dermatol , vol.77 , pp. 180-185
    • Sneddon, I.B.1
  • 222
    • 30944455907 scopus 로고    scopus 로고
    • Sneddon?s syndrome as a disorder of small arteries with endothelial cells proliferation: Ultrastructural and neuroimaging study
    • Lewandowska E, Wierzba-Bobrowicz T, Wagner T, et al. Sneddon?s syndrome as a disorder of small arteries with endothelial cells proliferation: ultrastructural and neuroimaging study. Folia Neuropathol 2005; 43: 345-354.
    • (2005) Folia Neuropathol , vol.43 , pp. 345-354
    • Lewandowska, E.1    Wierzba-Bobrowicz, T.2    Wagner, T.3
  • 223
    • 0029442320 scopus 로고
    • Sneddon?s syndrome with bilateral peripheral retinal neovascularization
    • Gobert A. Sneddon?s syndrome with bilateral peripheral retinal neovascularization. Bull Soc Belge Ophtalmol 1995; 255: 85-90.
    • (1995) Bull Soc Belge Ophtalmol , vol.255 , pp. 85-90
    • Gobert, A.1
  • 224
    • 0031687675 scopus 로고    scopus 로고
    • Sneddon?s syndrome: Neuro-ophthalmologic manifestations in a possible autosomal recessive pattern
    • Rehany U, Kassif Y and Rumelt S. Sneddon?s syndrome: neuro-ophthalmologic manifestations in a possible autosomal recessive pattern. Neurology 1998; 51: 1185-1187.
    • (1998) Neurology , vol.51 , pp. 1185-1187
    • Rehany, U.1    Kassif, Y.2    Rumelt, S.3
  • 225
    • 84911471579 scopus 로고    scopus 로고
    • Neural correlates of fatigue in granulomatosis with polyangiitis: A functional magnetic resonance imaging study
    • Basu N, Murray AD, Jones GT, et al. Neural correlates of fatigue in granulomatosis with polyangiitis: a functional magnetic resonance imaging study. Rheumatology (Oxford) 2014; 53: 2080-2087.
    • (2014) Rheumatology (Oxford) , vol.53 , pp. 2080-2087
    • Basu, N.1    Murray, A.D.2    Jones, G.T.3
  • 226
    • 84901550466 scopus 로고    scopus 로고
    • Update on varicella zoster virus vasculopathy
    • Nagel MA and Gilden D. Update on varicella zoster virus vasculopathy. Curr Infect Dis Rep 2014; 16: 407.
    • (2014) Curr Infect Dis Rep , vol.16 , pp. 407
    • Nagel, M.A.1    Gilden, D.2
  • 227
    • 84863115545 scopus 로고    scopus 로고
    • Hepatitis C virus infects the endothelial cells of the blood-brain barrier
    • Fletcher NF, Wilson GK, Murray J, et al. Hepatitis C virus infects the endothelial cells of the blood-brain barrier. Gastroenterology 2012; 142: 634-643.e6.
    • (2012) Gastroenterology , vol.142 , pp. 634-634e6
    • Fletcher, N.F.1    Wilson, G.K.2    Murray, J.3
  • 228
    • 0035065318 scopus 로고    scopus 로고
    • Vasculitides associated with HIV infection
    • Chetty R. Vasculitides associated with HIV infection. J Clin Pathol 2001; 54: 275-278.
    • (2001) J Clin Pathol , vol.54 , pp. 275-278
    • Chetty, R.1
  • 229
    • 84855899694 scopus 로고    scopus 로고
    • Recent developments regarding human immunodeficiency virus infection and stroke
    • Sen S, Rabinstein AA, Elkind MS, et al. Recent developments regarding human immunodeficiency virus infection and stroke. Cerebrovasc Dis 2012; 33: 209-218.
    • (2012) Cerebrovasc Dis , vol.33 , pp. 209-218
    • Sen, S.1    Rabinstein, A.A.2    Elkind, M.S.3
  • 230
    • 34247178647 scopus 로고    scopus 로고
    • Mechanisms of ischemic stroke in HIV-infected patients
    • Ortiz G, Koch S, Romano JG, et al. Mechanisms of ischemic stroke in HIV-infected patients. Neurology 2007; 68: 1257-1261.
    • (2007) Neurology , vol.68 , pp. 1257-1261
    • Ortiz, G.1    Koch, S.2    Romano, J.G.3
  • 232
    • 84866447961 scopus 로고    scopus 로고
    • HIV infection and stroke: Current perspectives and future directions
    • Benjamin LA, Bryer A, Emsley HC, et al. HIV infection and stroke: current perspectives and future directions. Lancet Neurol 2012; 11: 878-890.
    • (2012) Lancet Neurol , vol.11 , pp. 878-890
    • Benjamin, L.A.1    Bryer, A.2    Emsley, H.C.3
  • 234
    • 0027436826 scopus 로고
    • Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism
    • Moses AV, Bloom FE, Pauza CD, et al. Human immunodeficiency virus infection of human brain capillary endothelial cells occurs via a CD4/galactosylceramide-independent mechanism. Proc Natl Acad Sci USA 1993; 90: 10474-10478.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 10474-10478
    • Moses, A.V.1    Bloom, F.E.2    Pauza, C.D.3
  • 235
    • 0037371137 scopus 로고    scopus 로고
    • HIV-1 Tatmediated apoptosis in human brain microvascular endothelial cells
    • Kim TA, Avraham HK, Koh YH, et al. HIV-1 Tatmediated apoptosis in human brain microvascular endothelial cells. J Immunol 2003; 170: 2629-2637.
    • (2003) J Immunol , vol.170 , pp. 2629-2637
    • Kim, T.A.1    Avraham, H.K.2    Koh, Y.H.3
  • 236
    • 84906545643 scopus 로고    scopus 로고
    • Tat 101-mediated enhancement of brain pericyte migration involves platelet-Derived growth factor subunit B homodimer: Implications for human immunodeficiency virus-Associated neurocognitive disorders
    • Niu F, Yao H, Zhang W, et al. Tat 101-mediated enhancement of brain pericyte migration involves platelet-Derived growth factor subunit B homodimer: implications for human immunodeficiency virus-Associated neurocognitive disorders. J Neurosci 2014; 34: 11812-11825.
    • (2014) J Neurosci , vol.34 , pp. 11812-11825
    • Niu, F.1    Yao, H.2    Zhang, W.3
  • 237
    • 53949108884 scopus 로고    scopus 로고
    • Biology and neuropathology of dementia in syphilis and Lyme disease
    • Miklossy J. Biology and neuropathology of dementia in syphilis and Lyme disease. Handb Clin Neurol 2008; 89: 825-844.
    • (2008) Handb Clin Neurol , vol.89 , pp. 825-844
    • Miklossy, J.1
  • 238
    • 0025111057 scopus 로고
    • Stroke in neuroborreliosis
    • May EF and Jabbari B. Stroke in neuroborreliosis. Stroke 1990; 21: 1232-1235.
    • (1990) Stroke , vol.21 , pp. 1232-1235
    • May, E.F.1    Jabbari, B.2
  • 239
    • 84869176373 scopus 로고    scopus 로고
    • Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: Role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5
    • Silva J, Polesskaya O, Knight W, et al. Transient hypercapnia reveals an underlying cerebrovascular pathology in a murine model for HIV-1 associated neuroinflammation: role of NO-cGMP signaling and normalization by inhibition of cyclic nucleotide phosphodiesterase-5. J Neuroinflamm 2012; 9: 253.
    • (2012) J Neuroinflamm , vol.9 , pp. 253
    • Silva, J.1    Polesskaya, O.2    Knight, W.3
  • 240
    • 65549118629 scopus 로고    scopus 로고
    • Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy
    • Fallon BA, Lipkin RB, Corbera KM, et al. Regional cerebral blood flow and metabolic rate in persistent Lyme encephalopathy. Arch Gen Psychiatry 2009; 66: 554-563.
    • (2009) Arch Gen Psychiatry , vol.66 , pp. 554-563
    • Fallon, B.A.1    Lipkin, R.B.2    Corbera, K.M.3
  • 241
    • 0842264994 scopus 로고    scopus 로고
    • Nailfold digital capillaroscopy in 447 patients with connective tissue disease and Raynaud?s disease
    • Nagy Z and Czirjak L. Nailfold digital capillaroscopy in 447 patients with connective tissue disease and Raynaud?s disease. J Eur Acad Dermatol Venereol 2004; 18: 62-68.
    • (2004) J Eur Acad Dermatol Venereol , vol.18 , pp. 62-68
    • Nagy, Z.1    Czirjak, L.2
  • 242
    • 57349116070 scopus 로고    scopus 로고
    • Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud?s phenomenon to systemic sclerosis: A twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis
    • Koenig M, Joyal F, Fritzler MJ, et al. Autoantibodies and microvascular damage are independent predictive factors for the progression of Raynaud?s phenomenon to systemic sclerosis: a twenty-year prospective study of 586 patients, with validation of proposed criteria for early systemic sclerosis. Arthritis Rheum 2008; 58: 3902-3912.
    • (2008) Arthritis Rheum , vol.58 , pp. 3902-3912
    • Koenig, M.1    Joyal, F.2    Fritzler, M.J.3
  • 243
    • 84889561159 scopus 로고    scopus 로고
    • Neurologic involvement in scleroderma: A systematic review
    • Amaral TN, Peres FA, Lapa AT, et al. Neurologic involvement in scleroderma: a systematic review. Semin Arthritis Rheum 2013; 43: 335-347.
    • (2013) Semin Arthritis Rheum , vol.43 , pp. 335-347
    • Amaral, T.N.1    Peres, F.A.2    Lapa, A.T.3
  • 244
    • 0344074662 scopus 로고    scopus 로고
    • Brain involvement in scleroderma: Two autopsy cases
    • Heron E, Fornes P, Rance A, et al. Brain involvement in scleroderma: two autopsy cases. Stroke 1998; 29: 719-721.
    • (1998) Stroke , vol.29 , pp. 719-721
    • Heron, E.1    Fornes, P.2    Rance, A.3
  • 245
    • 0030728387 scopus 로고    scopus 로고
    • Impaired quantitative cerebral blood flow in scleroderma patients
    • Nobili F, Cutolo M, Sulli A, et al. Impaired quantitative cerebral blood flow in scleroderma patients. J Neurol Sci 1997; 152: 63-71.
    • (1997) J Neurol Sci , vol.152 , pp. 63-71
    • Nobili, F.1    Cutolo, M.2    Sulli, A.3
  • 246
    • 0034502278 scopus 로고    scopus 로고
    • Evidence of cerebral hypoperfusion in scleroderma patients
    • Cutolo M, Nobili F, Sulli A, et al. Evidence of cerebral hypoperfusion in scleroderma patients. Rheumatology (Oxford) 2000; 39: 1366-1373.
    • (2000) Rheumatology (Oxford) , vol.39 , pp. 1366-1373
    • Cutolo, M.1    Nobili, F.2    Sulli, A.3
  • 247
    • 0028000453 scopus 로고
    • Cardiac and central nervous system vasculitis in a child with dermatomyositis
    • Jimenez C, Rowe PC and Keene D. Cardiac and central nervous system vasculitis in a child with dermatomyositis. J Child Neurol 1994; 9: 297-300.
    • (1994) J Child Neurol , vol.9 , pp. 297-300
    • Jimenez, C.1    Rowe, P.C.2    Keene, D.3


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