메뉴 건너뛰기




Volumn 34, Issue 35, 2014, Pages 11812-11825

Tat 101-mediated enhancement of brain pericyte migration involves platelet-derived growth factor subunit B homodimer: Implications for human immunodeficiency virus-associated neurocognitive disorders

Author keywords

BBB; HIV Tat; PDGF BB; Pericytes

Indexed keywords

HOMODIMER; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; PLATELET DERIVED GROWTH FACTOR B; PROTEIN TAT 101; SMALL INTERFERING RNA; STRESS ACTIVATED PROTEIN KINASE; TRANSACTIVATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84906545643     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.1139-14.2014     Document Type: Article
Times cited : (50)

References (49)
  • 1
    • 84855760098 scopus 로고    scopus 로고
    • HIV-1 Tat neurotoxicity: A model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes
    • CrossRef Medline
    • Agrawal L., Louboutin JP, Reyes BA, Van Bockstaele EJ, Strayer DS (2012) HIV-1 Tat neurotoxicity: a model of acute and chronic exposure, and neuroprotection by gene delivery of antioxidant enzymes. Neurobiol Dis 45:657-670. CrossRef Medline
    • (2012) Neurobiol Dis , vol.45 , pp. 657-670
    • Agrawal, L.1    Louboutin, J.P.2    Reyes, B.A.3    Van Bockstaele, E.J.4    Strayer, D.S.5
  • 2
    • 16244400107 scopus 로고    scopus 로고
    • Permeability of the blood-brain barrier to HIV-1 Tat
    • CrossRef Medline
    • Banks W. A, Robinson SM, Nath A (2005) Permeability of the blood-brain barrier to HIV-1 Tat. Exp Neurol 193:218-227. CrossRef Medline
    • (2005) Exp Neurol , vol.193 , pp. 218-227
    • Banks, W.A.1    Robinson, S.M.2    Nath, A.3
  • 3
    • 78049279739 scopus 로고    scopus 로고
    • Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging
    • CrossRef Medline
    • Bell R. D, Winkler EA, Sagare AP, Singh I, LaRue B, Deane R, Zlokovic BV (2010) Pericytes control key neurovascular functions and neuronal phenotype in the adult brain and during brain aging. Neuron 68:409-427. CrossRef Medline
    • (2010) Neuron , vol.68 , pp. 409-427
    • Bell, R.D.1    Winkler, E.A.2    Sagare, A.P.3    Singh, I.4    LaRue, B.5    Deane, R.6    Zlokovic, B.V.7
  • 4
    • 79954992762 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: Role of early growth response gene 1
    • CrossRef Medline
    • Bethel-Brown C., Yao H, Callen S, Lee YH, Dash PK, Kumar A, Buch S (2011) HIV-1 Tat-mediated induction of platelet-derived growth factor in astrocytes: role of early growth response gene 1. J Immunol 186:4119-4129. CrossRef Medline
    • (2011) J Immunol , vol.186 , pp. 4119-4129
    • Bethel-Brown, C.1    Yao, H.2    Callen, S.3    Lee, Y.H.4    Dash, P.K.5    Kumar, A.6    Buch, S.7
  • 5
    • 84870213148 scopus 로고    scopus 로고
    • Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: Implications for HIV-associated neuroinflammation
    • CrossRef Medline
    • Bethel-Brown C., Yao H, HuG, Buch S (2012) Platelet-derived growth factor (PDGF)-BB-mediated induction of monocyte chemoattractant protein 1 in human astrocytes: implications for HIV-associated neuroinflammation. J Neuroinflammation 9:262. CrossRef Medline
    • (2012) J Neuroinflammation , vol.9 , pp. 262
    • Bethel-Brown, C.1    Yao, H.2    Hu, G.3    Buch, S.4
  • 6
    • 34248592116 scopus 로고    scopus 로고
    • Human immunodeficiency virus type-1 protein Tat induces tumor necrosis factor-alpha-mediated neurotoxicity
    • CrossRef Medline
    • Buscemi L., Ramonet D, Geiger JD (2007) Human immunodeficiency virus type-1 protein Tat induces tumor necrosis factor-alpha-mediated neurotoxicity. Neurobiol Dis 26:661-670. CrossRef Medline
    • (2007) Neurobiol Dis , vol.26 , pp. 661-670
    • Buscemi, L.1    Ramonet, D.2    Geiger, J.D.3
  • 7
    • 66949161978 scopus 로고    scopus 로고
    • The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-α B translocation and PDGF production
    • CrossRef Medline
    • Chung C. H, Lin KT, Chang CH, Peng HC, Huang TF (2009) The integrin alpha2beta1 agonist, aggretin, promotes proliferation and migration of VSMC through NF-α B translocation and PDGF production. Br J Pharmacol 156:846-856. CrossRef Medline
    • (2009) Br J Pharmacol , vol.156 , pp. 846-856
    • Chung, C.H.1    Lin, K.T.2    Chang, C.H.3    Peng, H.C.4    Huang, T.F.5
  • 9
    • 84879488912 scopus 로고    scopus 로고
    • Brain pericytes increase the lipopolysaccharideenhanced transcytosis of HIV-1 free virus across the in vitro blood-brain barrier: Evidence for cytokine-mediated pericyte-endothelial cell crosstalk
    • CrossRef Medline
    • Dohgu S., BanksWA (2013) Brain pericytes increase the lipopolysaccharideenhanced transcytosis of HIV-1 free virus across the in vitro blood-brain barrier: evidence for cytokine-mediated pericyte-endothelial cell crosstalk. Fluids Barriers C. NS 10:23. CrossRef Medline
    • (2013) Fluids Barriers C. NS , vol.10 , pp. 23
    • Dohgu, S.1    Banks, W.A.2
  • 10
    • 33847649975 scopus 로고    scopus 로고
    • HIV-tat induces formation of an LRP-PSD-95-NMDARnNOS complex that promotes apoptosis in neurons and astrocytes
    • CrossRef Medline
    • Eugenin E. A, King JE, Nath A, Calderon TM, Zukin RS, Bennett MV, Berman JW (2007) HIV-tat induces formation of an LRP-PSD-95-NMDARnNOS complex that promotes apoptosis in neurons and astrocytes. Proc Natl Acad Sci U S A 104:3438-3443. CrossRef Medline
    • (2007) Proc Natl Acad Sci U S A , vol.104 , pp. 3438-3443
    • Eugenin, E.A.1    King, J.E.2    Nath, A.3    Calderon, T.M.4    Zukin, R.S.5    Bennett, M.V.6    Berman, J.W.7
  • 11
    • 79960003831 scopus 로고    scopus 로고
    • Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism
    • CrossRef Medline
    • Eugenin E. A, Clements JE, Zink MC, Berman JW (2011) Human immunodeficiency virus infection of human astrocytes disrupts blood-brain barrier integrity by a gap junction-dependent mechanism. J Neurosci 31: 9456-9465. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 9456-9465
    • Eugenin, E.A.1    Clements, J.E.2    Zink, M.C.3    Berman, J.W.4
  • 12
    • 67650504966 scopus 로고    scopus 로고
    • TScratch: A novel and simple software tool for automated analysis of monolayer wound healing assays
    • CrossRef Medline
    • Gebäck T., Schulz MM, Koumoutsakos P, Detmar M (2009) TScratch: a novel and simple software tool for automated analysis of monolayer wound healing assays. Biotechniques 46:265-274. CrossRef Medline
    • (2009) Biotechniques , vol.46 , pp. 265-274
    • Gebäck, T.1    Schulz, M.M.2    Koumoutsakos, P.3    Detmar, M.4
  • 14
    • 70349769521 scopus 로고    scopus 로고
    • Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients
    • CrossRef Medline
    • Hsue P. Y, Hunt PW, Wu Y, Schnell A, Ho JE, Hatano H, Xie Y, Martin JN, Ganz P., Deeks SG (2009) Association of abacavir and impaired endothelial function in treated and suppressed HIV-infected patients. AIDS 23:2021-2027. CrossRef Medline
    • (2009) AIDS , vol.23 , pp. 2021-2027
    • Hsue, P.Y.1    Hunt, P.W.2    Wu, Y.3    Schnell, A.4    Ho, J.E.5    Hatano, H.6    Xie, Y.7    Martin, J.N.8    Ganz, P.9    Deeks, S.G.10
  • 15
    • 27644478283 scopus 로고    scopus 로고
    • Genomic profiling of the neuronal target genes of the plasticity-related transcription factor-Zif268
    • CrossRef Medline
    • James A. B, Conway AM, Morris BJ (2005) Genomic profiling of the neuronal target genes of the plasticity-related transcription factor-Zif268. J Neurochem 95:796-810. CrossRef Medline
    • (2005) J Neurochem , vol.95 , pp. 796-810
    • James, A.B.1    Conway, A.M.2    Morris, B.J.3
  • 16
    • 0028982830 scopus 로고
    • Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress
    • CrossRef Medline
    • Khachigian L. M, Resnick N, Gimbrone MA Jr, Collins T (1995) Nuclear factor-kappa B interacts functionally with the platelet-derived growth factor B-chain shear-stress response element in vascular endothelial cells exposed to fluid shear stress. J Clin Invest 96:1169-1175. CrossRef Medline
    • (1995) J Clin Invest , vol.96 , pp. 1169-1175
    • Khachigian, L.M.1    Resnick, N.2    Gimbrone Jr., M.A.3    Collins, T.4
  • 17
    • 0029996110 scopus 로고    scopus 로고
    • Egr-1-induced endothelial gene expression: A common theme in vascular injury
    • CrossRef Medline
    • Khachigian L. M, Lindner V, Williams AJ, Collins T (1996) Egr-1-induced endothelial gene expression: a common theme in vascular injury. Science 271:1427-1431. CrossRef Medline
    • (1996) Science , vol.271 , pp. 1427-1431
    • Khachigian, L.M.1    Lindner, V.2    Williams, A.J.3    Collins, T.4
  • 18
    • 0037371137 scopus 로고    scopus 로고
    • HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells
    • CrossRef Medline
    • Kim T. A, Avraham HK, Koh YH, Jiang S, Park IW, Avraham S (2003) HIV-1 Tat-mediated apoptosis in human brain microvascular endothelial cells. J Immunol 170:2629-2637. CrossRef Medline
    • (2003) J Immunol , vol.170 , pp. 2629-2637
    • Kim, T.A.1    Avraham, H.K.2    Koh, Y.H.3    Jiang, S.4    Park, I.W.5    Avraham, S.6
  • 19
  • 20
    • 0030756325 scopus 로고    scopus 로고
    • Pericyte loss and microaneurysm formation in PDGF-B-deficient mice
    • CrossRef Medline
    • Lindahl P., Johansson BR, Levéen P, Betsholtz C (1997) Pericyte loss and microaneurysm formation in PDGF-B-deficient mice. Science 277:242-245. CrossRef Medline
    • (1997) Science , vol.277 , pp. 242-245
    • Lindahl, P.1    Johansson, B.R.2    Levéen, P.3    Betsholtz, C.4
  • 21
    • 0034529953 scopus 로고    scopus 로고
    • Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands
    • CrossRef Medline
    • Liu Y., Jones M, Hingtgen CM, Bu G, Laribee N, Tanzi RE, Moir RD, Nath A, He J. J (2000) Uptake of HIV-1 tat protein mediated by low-density lipoprotein receptor-related protein disrupts the neuronal metabolic balance of the receptor ligands. Nat Med 6:1380-1387. CrossRef Medline
    • (2000) Nat Med , vol.6 , pp. 1380-1387
    • Liu, Y.1    Jones, M.2    Hingtgen, C.M.3    Bu, G.4    Laribee, N.5    Tanzi, R.E.6    Moir, R.D.7    Nath, A.8    He, J.J.9
  • 22
    • 77953715510 scopus 로고    scopus 로고
    • Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon
    • CrossRef Medline
    • López-Huertas M. R, Callejas S, Abia D, Mateos E, Dopazo A, Alcamí J, Coiras M (2010) Modifications in host cell cytoskeleton structure and function mediated by intracellular HIV-1 Tat protein are greatly dependent on the second coding exon. Nucleic Acids Res 38:3287-3307. CrossRef Medline
    • (2010) Nucleic Acids Res , vol.38 , pp. 3287-3307
    • López-Huertas, M.R.1    Callejas, S.2    Abia, D.3    Mateos, E.4    Dopazo, A.5    Alcamí, J.6    Coiras, M.7
  • 24
    • 77952940200 scopus 로고    scopus 로고
    • Human immunodeficiency virus-associated neurocognitive disorders: Mind the gap
    • CrossRef Medline
    • McArthur J. C, Steiner J, Sacktor N, Nath A (2010) Human immunodeficiency virus-associated neurocognitive disorders: mind the gap. Ann Neurol 67:699-714. CrossRef Medline
    • (2010) Ann Neurol , vol.67 , pp. 699-714
    • McArthur, J.C.1    Steiner, J.2    Sacktor, N.3    Nath, A.4
  • 25
    • 34547662268 scopus 로고    scopus 로고
    • Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content
    • CrossRef Medline
    • McCarty M. F, Somcio RJ, Stoeltzing O, Wey J, Fan F, Liu W, Bucana C, Ellis LM (2007) Overexpression of PDGF-BB decreases colorectal and pancreatic cancer growth by increasing tumor pericyte content. J Clin Invest 117:2114-2122. CrossRef Medline
    • (2007) J Clin Invest , vol.117 , pp. 2114-2122
    • McCarty, M.F.1    Somcio, R.J.2    Stoeltzing, O.3    Wey, J.4    Fan, F.5    Liu, W.6    Bucana, C.7    Ellis, L.M.8
  • 27
    • 79961110896 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-1 alpha/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling
    • CrossRef Medline
    • Mermis J., Gu H, Xue B, Li F, Tawfik O, Buch S, Bartolome S, O'Brien-Ladner A, Dhillon NK (2011) Hypoxia-inducible factor-1 alpha/platelet derived growth factor axis in HIV-associated pulmonary vascular remodeling. Respir Res 12:103. CrossRef Medline
    • (2011) Respir Res , vol.12 , pp. 103
    • Mermis, J.1    Gu, H.2    Xue, B.3    Li, F.4    Tawfik, O.5    Buch, S.6    Bartolome, S.7    O'Brien-Ladner, A.8    Dhillon, N.K.9
  • 28
    • 0036085160 scopus 로고    scopus 로고
    • Angiotensin II stimulates migration of retinal microvascular pericytes: Involvement of TGF-beta and PDGF-BB
    • CrossRef Medline
    • Nadal J. A, Scicli GM, Carbini LA, Scicli AG (2002) Angiotensin II stimulates migration of retinal microvascular pericytes: involvement of TGF-beta and PDGF-BB. Am J Physiol Heart Circ Physiol 282:H739-H748. CrossRef Medline
    • (2002) Am J Physiol Heart Circ Physiol , vol.282
    • Nadal, J.A.1    Scicli, G.M.2    Carbini, L.A.3    Scicli, A.G.4
  • 29
    • 84871102484 scopus 로고    scopus 로고
    • Infection of human pericytes by HIV-1 disrupts the integrity of the blood-brain barrier
    • CrossRef Medline
    • Nakagawa S., Castro V, Toborek M (2012) Infection of human pericytes by HIV-1 disrupts the integrity of the blood-brain barrier. J Cell Mol Med 16:2950-2957. CrossRef Medline
    • (2012) J Cell Mol Med , vol.16 , pp. 2950-2957
    • Nakagawa, S.1    Castro, V.2    Toborek, M.3
  • 30
    • 84873896549 scopus 로고    scopus 로고
    • Inhibition of glycogen synthase kinase 3beta promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5
    • CrossRef Medline
    • Ramirez S. H, Fan S, Dykstra H, RomS, Mercer A, Reichenbach NL, Gofman L, Persidsky Y. (2013) Inhibition of glycogen synthase kinase 3beta promotes tight junction stability in brain endothelial cells by half-life extension of occludin and claudin-5. PLoS One 8:e55972. CrossRef Medline
    • (2013) PLoS One , vol.8
    • Ramirez, S.H.1    Fan, S.2    Dykstra, H.3    Rom, S.4    Mercer, A.5    Reichenbach, N.L.6    Gofman, L.7    Persidsky, Y.8
  • 31
    • 33947680768 scopus 로고    scopus 로고
    • HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: New insights into blood-brain barrier dysfunction for HIV-1-associated dementia
    • CrossRef Medline
    • Ricardo-Dukelow M., Kadiu I, Rozek W, Schlautman J, Persidsky Y, Ciborowski P, Kanmogne GD, Gendelman HE (2007) HIV-1 infected monocyte-derived macrophages affect the human brain microvascular endothelial cell proteome: new insights into blood-brain barrier dysfunction for HIV-1-associated dementia. J Neuroimmunol 185:37-46. CrossRef Medline
    • (2007) J Neuroimmunol , vol.185 , pp. 37-46
    • Ricardo-Dukelow, M.1    Kadiu, I.2    Rozek, W.3    Schlautman, J.4    Persidsky, Y.5    Ciborowski, P.6    Kanmogne, G.D.7    Gendelman, H.E.8
  • 32
    • 33845625199 scopus 로고    scopus 로고
    • Interaction of HIV Tat and matrix metalloproteinase in HIV neuropathogenesis: A new host defense mechanism
    • CrossRef Medline
    • Rumbaugh J., Turchan-Cholewo J, Galey D, St Hillaire C, Anderson C, Conant K, Nath A (2006) Interaction of HIV Tat and matrix metalloproteinase in HIV neuropathogenesis: a new host defense mechanism. FASEB J 20:1736-1738. CrossRef Medline
    • (2006) FASEB J , vol.20 , pp. 1736-1738
    • Rumbaugh, J.1    Turchan-Cholewo, J.2    Galey, D.3    St. Hillaire, C.4    Anderson, C.5    Conant, K.6    Nath, A.7
  • 33
    • 84885867527 scopus 로고    scopus 로고
    • High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: Implications for cerebral microvascular disease in diabetes
    • CrossRef Medline
    • Shah G. N, Morofuji Y, Banks WA, Price TO (2013) High glucose-induced mitochondrial respiration and reactive oxygen species in mouse cerebral pericytes is reversed by pharmacological inhibition of mitochondrial carbonic anhydrases: implications for cerebral microvascular disease in diabetes. Biochem Biophys Res Commun 440:354-358. CrossRef Medline
    • (2013) Biochem Biophys Res Commun , vol.440 , pp. 354-358
    • Shah, G.N.1    Morofuji, Y.2    Banks, W.A.3    Price, T.O.4
  • 34
    • 0033000998 scopus 로고    scopus 로고
    • Pathways of Egr-1-mediated gene transcription in vascular biology
    • CrossRef Medline
    • Silverman E. S, Collins T (1999) Pathways of Egr-1-mediated gene transcription in vascular biology. Am J Pathol 154:665-670. CrossRef Medline
    • (1999) Am J Pathol , vol.154 , pp. 665-670
    • Silverman, E.S.1    Collins, T.2
  • 35
    • 78649455280 scopus 로고    scopus 로고
    • Endothelialderived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization
    • CrossRef Medline
    • Stratman A. N, Schwindt AE, Malotte KM, Davis GE (2010) Endothelialderived PDGF-BB and HB-EGF coordinately regulate pericyte recruitment during vasculogenic tube assembly and stabilization. Blood 116: 4720-4730. CrossRef Medline
    • (2010) Blood , vol.116 , pp. 4720-4730
    • Stratman, A.N.1    Schwindt, A.E.2    Malotte, K.M.3    Davis, G.E.4
  • 39
    • 80055014830 scopus 로고    scopus 로고
    • Central nervous system pericytes in health and disease
    • CrossRef Medline
    • Winkler E. A, Bell RD, Zlokovic BV (2011) Central nervous system pericytes in health and disease. Nat Neurosci 14:1398-1405. CrossRef Medline
    • (2011) Nat Neurosci , vol.14 , pp. 1398-1405
    • Winkler, E.A.1    Bell, R.D.2    Zlokovic, B.V.3
  • 41
    • 84855991429 scopus 로고    scopus 로고
    • HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9
    • CrossRef Medline
    • Xu R., Feng X, Xie X, Zhang J, Wu D, Xu L (2012) HIV-1 Tat protein increases the permeability of brain endothelial cells by both inhibiting occludin expression and cleaving occludin via matrix metalloproteinase-9. Brain Res 1436:13-19. CrossRef Medline
    • (2012) Brain Res , vol.1436 , pp. 13-19
    • Xu, R.1    Feng, X.2    Xie, X.3    Zhang, J.4    Wu, D.5    Xu, L.6
  • 42
    • 67650318972 scopus 로고    scopus 로고
    • Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways
    • CrossRef Medline
    • Yao H., Allen JE, Zhu X, Callen S, Buch S (2009) Cocaine and human immunodeficiency virus type 1 gp120 mediate neurotoxicity through overlapping signaling pathways. J Neurovirol 15:164-175. CrossRef Medline
    • (2009) J Neurovirol , vol.15 , pp. 164-175
    • Yao, H.1    Allen, J.E.2    Zhu, X.3    Callen, S.4    Buch, S.5
  • 43
    • 77954703072 scopus 로고    scopus 로고
    • Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: Implication for increased monocyte transmigration
    • CrossRef Medline
    • Yao H., Yang Y, Kim KJ, Bethel-Brown C, Gong N, Funa K, Gendelman HE, Su TP, Wang JQ, Buch S (2010) Molecular mechanisms involving sigma receptor-mediated induction of MCP-1: implication for increased monocyte transmigration. Blood 115:4951-4962. CrossRef Medline
    • (2010) Blood , vol.115 , pp. 4951-4962
    • Yao, H.1    Yang, Y.2    Kim, K.J.3    Bethel-Brown, C.4    Gong, N.5    Funa, K.6    Gendelman, H.E.7    Su, T.P.8    Wang, J.Q.9    Buch, S.10
  • 44
    • 79952158505 scopus 로고    scopus 로고
    • Cocaine-mediated induction of plateletderived growth factor: Implication for increased vascular permeability
    • CrossRef Medline
    • Yao H., Duan M, Buch S (2011a) Cocaine-mediated induction of plateletderived growth factor: implication for increased vascular permeability. Blood 117:2538-2547. CrossRef Medline
    • (2011) Blood , vol.117 , pp. 2538-2547
    • Yao, H.1    Duan, M.2    Buch, S.3
  • 45
    • 79955783940 scopus 로고    scopus 로고
    • Cocaine hijacks sigma1 receptor to initiate induction of activated leukocyte cell adhesion molecule: Implication for increased monocyte adhesion and migration in the CNS
    • CrossRef Medline
    • Yao H., Kim K, Duan M, Hayashi T, Guo M, Morgello S, Prat A, Wang J, Su TP, Buch S (2011b) Cocaine hijacks sigma1 receptor to initiate induction of activated leukocyte cell adhesion molecule: implication for increased monocyte adhesion and migration in the CNS. J Neurosci 31: 5942-5955. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 5942-5955
    • Yao, H.1    Kim, K.2    Duan, M.3    Hayashi, T.4    Guo, M.5    Morgello, S.6    Prat, A.7    Wang, J.8    Su, T.P.9    Buch, S.10
  • 46
    • 84875725468 scopus 로고    scopus 로고
    • Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: Involvement of beta1 integrins
    • CrossRef Medline
    • Yao H., Duan M, Yang L, Buch S (2013) Nonmuscle myosin light-chain kinase mediates microglial migration induced by HIV Tat: involvement of beta1 integrins. FASEB J 27:1532-1548. CrossRef Medline
    • (2013) FASEB J , vol.27 , pp. 1532-1548
    • Yao, H.1    Duan, M.2    Yang, L.3    Buch, S.4
  • 47
    • 84879082098 scopus 로고    scopus 로고
    • Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells
    • CrossRef Medline
    • Zechariah A., ElAli A, Hagemann N, Jin F, Doeppner TR, Helfrich I, Mies G, Hermann DM (2013) Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells. Arterioscler Thromb Vasc Biol 33:1561-1567. CrossRef Medline
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 1561-1567
    • Zechariah, A.1    ElAli, A.2    Hagemann, N.3    Jin, F.4    Doeppner, T.R.5    Helfrich, I.6    Mies, G.7    Hermann, D.M.8
  • 48
    • 84855955859 scopus 로고    scopus 로고
    • HIV-1 Tat triggers nuclear localization of ZO-1 via Rho signaling and cAMP response element-binding protein activation
    • CrossRef Medline
    • Zhong Y., Zhang B, Eum SY, Toborek M (2012) HIV-1 Tat triggers nuclear localization of ZO-1 via Rho signaling and cAMP response element-binding protein activation. J Neurosci 32:143-150. CrossRef Medline
    • (2012) J Neurosci , vol.32 , pp. 143-150
    • Zhong, Y.1    Zhang, B.2    Eum, S.Y.3    Toborek, M.4
  • 49
    • 7444220727 scopus 로고    scopus 로고
    • Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes
    • CrossRef Medline
    • Zhou B. Y, Liu Y, Kim Bo, Xiao Y, He JJ (2004) Astrocyte activation and dysfunction and neuron death by HIV-1 Tat expression in astrocytes. Mol Cell Neurosci 27:296-305. CrossRef Medline
    • (2004) Mol Cell Neurosci , vol.27 , pp. 296-305
    • Zhou, B.Y.1    Liu, Y.2    Kim, B.3    Xiao, Y.4    He, J.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.