Reduced cerebrovascular reactivity in young adults carrying the APOE ε4 allele

Alzheimer's and Dementia

Volumn 11, Issue 6, 2015, Pages 648-657.e1

  Suri, Sana ^a,b   Mackay, Clare E ^a,b   Kelly, Michael E ^b   Germuska, Michael ^b   Tunbridge, Elizabeth M ^a   Frisoni, Giovanni B ^c,d   Matthews, Paul M ^e   Ebmeier, Klaus P ^a   Bulte, Daniel P ^b   Filippini, Nicola ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c IRCCS ISTITUTO CENTRO SAN GIOVANNI DI DIO FATEBENEFRATELLI   (Italy)

^d UNIVERSITY OF GENEVA   (Switzerland)

^e IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

Alzheimer's disease; APOE gene; BOLD; Cerebrovascular reactivity; fMRI

Indexed keywords

APOLIPOPROTEIN E2; APOLIPOPROTEIN E4; CARBON DIOXIDE; OXYGEN;

ADULT; ALLELE; APOE EPSILON2 GENE; APOE EPSILON4 GENE; ARTICLE; BLOOD VESSEL REACTIVITY; BOLD SIGNAL; BRAIN BLOOD VESSEL; BRAIN REGION; BRAIN SIZE; CARBON DIOXIDE BREATHING; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENETIC SUSCEPTIBILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; HUMAN EXPERIMENT; MALE; MEMORY; NORMAL HUMAN; PERFUSION WEIGHTED IMAGING; PRIORITY JOURNAL; TASK PERFORMANCE; YOUNG ADULT; BLOOD; BRAIN; BRAIN CIRCULATION; BRAIN MAPPING; GENETICS; METABOLISM; NEUROPSYCHOLOGICAL TEST; NUCLEAR MAGNETIC RESONANCE IMAGING; PATTERN RECOGNITION; PHYSIOLOGY; RECOGNITION;

ADULT; APOLIPOPROTEIN E4; BRAIN; BRAIN MAPPING; CARBON DIOXIDE; CEREBROVASCULAR CIRCULATION; FEMALE; GENOTYPE; HETEROZYGOTE; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; NEUROPSYCHOLOGICAL TESTS; OXYGEN; PATTERN RECOGNITION, VISUAL; RECOGNITION (PSYCHOLOGY); YOUNG ADULT;

EID: 84931036843     PISSN: 15525260     EISSN: 15525279     Source Type: Journal    
DOI: 10.1016/j.jalz.2014.05.1755     Document Type: Article

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