Angiotensin II impairs neurovascular coupling in neocortex through NADPH oxidase-derived radicals

Circulation Research

Volumn 95, Issue 10, 2004, Pages 1019-1026

  Kazama, Ken ^a   Anrather, Josef ^a   Zhou, Ping ^a   Girouard, Helene ^a   Frys, Kelly ^a   Milner, Teresa A ^a   Iadecola, Costantino ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Division of Neurobiology   (United States)

Author keywords

Cerebral circulation; gp91 null mice; Hypertension; Laser Doppler flowmetry; Somatosensory activation

Indexed keywords

ANGIOTENSIN; ANGIOTENSIN 1 RECEPTOR; APOCYNIN; GLYCOPROTEIN GP 91; LOSARTAN; MANGANESE TETRAKIS (4 BENZOIC ACID) PORPHYRIN; PORPHYRIN DERIVATIVE; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SUPEROXIDE DISMUTASE; TIRON; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD VESSEL; BRAIN CIRCULATION; CONTROLLED STUDY; HYPEREMIA; HYPERTENSION; LASER DOPPLER FLOWMETRY; MALE; MOUSE; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT; SOMATOSENSORY CORTEX; VIBRISSA;

ACETOPHENONES; AMINO ACID SEQUENCE; ANGIOTENSIN II; ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANIMALS; ARTERIOLES; CEREBROVASCULAR CIRCULATION; CYTOCHROMES B; ENDOTHELIUM, VASCULAR; FREE RADICAL SCAVENGERS; FREE RADICALS; GLYCOPROTEINS; HYPERCAPNIA; HYPEREMIA; HYPERTENSION; LASER-DOPPLER FLOWMETRY; LOSARTAN; MALE; MEMBRANE GLYCOPROTEINS; METALLOPORPHYRINS; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MUSCLE, SMOOTH, VASCULAR; NADPH OXIDASE; NITRIC OXIDE DONORS; POLYETHYLENE GLYCOLS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; RECEPTOR, ANGIOTENSIN, TYPE 1; S-NITROSO-N-ACETYLPENICILLAMINE; SOMATOSENSORY CORTEX; SUPEROXIDE DISMUTASE; TIRON; VIBRISSAE;

EID: 8844227341     PISSN: 00097330     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.RES.0000148637.85595.c5     Document Type: Article

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