-
1
-
-
84875441083
-
The changing scene of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3sXjsVOiur4%3D, PID: 23463272
-
Robberecht W, Philips T (2013) The changing scene of amyotrophic lateral sclerosis. Nat Rev Neurosci 14:248–264
-
(2013)
Nat Rev Neurosci
, vol.14
, pp. 248-264
-
-
Robberecht, W.1
Philips, T.2
-
2
-
-
82955168362
-
Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation
-
COI: 1:CAS:528:DC%2BC3MXhs1SksbfI, PID: 22152301
-
Belanger M, Allaman I, Magistretti PJ (2011) Brain energy metabolism: focus on astrocyte-neuron metabolic cooperation. Cell Metab 14:724–738
-
(2011)
Cell Metab
, vol.14
, pp. 724-738
-
-
Belanger, M.1
Allaman, I.2
Magistretti, P.J.3
-
3
-
-
84865961091
-
Synaptic energy use and supply
-
COI: 1:CAS:528:DC%2BC38XhtlSkurvN, PID: 22958818
-
Harris JJ, Jolivet R, Attwell D (2012) Synaptic energy use and supply. Neuron 75:762–777
-
(2012)
Neuron
, vol.75
, pp. 762-777
-
-
Harris, J.J.1
Jolivet, R.2
Attwell, D.3
-
4
-
-
84885023188
-
Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain
-
PID: 23921897
-
Schonfeld P, Reiser G (2013) Why does brain metabolism not favor burning of fatty acids to provide energy? Reflections on disadvantages of the use of free fatty acids as fuel for brain. J Cereb Blood Flow Metab 33:1493–1499
-
(2013)
J Cereb Blood Flow Metab
, vol.33
, pp. 1493-1499
-
-
Schonfeld, P.1
Reiser, G.2
-
5
-
-
67349095741
-
Blood lactate is an important energy source for the human brain
-
PID: 19337275
-
van Hall G, Stromstad M, Rasmussen P, Jans O, Zaar M, Gam C, Quistorff B, Secher NH, Nielsen HB (2009) Blood lactate is an important energy source for the human brain. J Cereb Blood Flow Metab 29:1121–1129
-
(2009)
J Cereb Blood Flow Metab
, vol.29
, pp. 1121-1129
-
-
van Hall, G.1
Stromstad, M.2
Rasmussen, P.3
Jans, O.4
Zaar, M.5
Gam, C.6
Quistorff, B.7
Secher, N.H.8
Nielsen, H.B.9
-
6
-
-
0000017491
-
Brain energy metabolism: an integrated cellular perspective
-
Bloom FE, Kupfer DJ, (eds), Raven, New York
-
Magistretti PJ, Pellerin L, Martin JL (1995) Brain energy metabolism: an integrated cellular perspective. In: Bloom FE, Kupfer DJ (eds) Psychopharmacology: the fourth generation of progress. Raven, New York, pp 657–670
-
(1995)
Psychopharmacology: the fourth generation of progress
, pp. 657-670
-
-
Magistretti, P.J.1
Pellerin, L.2
Martin, J.L.3
-
8
-
-
0242406757
-
Lactate is a preferential oxidative energy substrate over glucose for neurons in culture
-
COI: 1:CAS:528:DC%2BD3sXos1CmtLY%3D, PID: 14600437
-
Bouzier-Sore A-K, Voisin P, Canioni P, Magistretti PJ, Pellerin L (2003) Lactate is a preferential oxidative energy substrate over glucose for neurons in culture. J Cereb Blood Flow Metab 23:1298–1306
-
(2003)
J Cereb Blood Flow Metab
, vol.23
, pp. 1298-1306
-
-
Bouzier-Sore, A.-K.1
Voisin, P.2
Canioni, P.3
Magistretti, P.J.4
Pellerin, L.5
-
9
-
-
0037782010
-
Lactate: a preferred fuel for human brain metabolism in vivo
-
COI: 1:CAS:528:DC%2BD3sXks1yqsLg%3D, PID: 12796713
-
Smith D, Pernet A, Hallett WA, Bingham E, Marsden PK, Amiel SA (2003) Lactate: a preferred fuel for human brain metabolism in vivo. J cereb Blood Flow Metab 23:658–664
-
(2003)
J cereb Blood Flow Metab
, vol.23
, pp. 658-664
-
-
Smith, D.1
Pernet, A.2
Hallett, W.A.3
Bingham, E.4
Marsden, P.K.5
Amiel, S.A.6
-
10
-
-
0029990892
-
Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain
-
COI: 1:CAS:528:DyaK28XmvVCjsb0%3D, PID: 8898679
-
Bittar PG, Charnay Y, Pellerin L, Bouras C, Magistretti PJ (1996) Selective distribution of lactate dehydrogenase isoenzymes in neurons and astrocytes of human brain. J Cereb Blood Flow Metab 16:1079–1089
-
(1996)
J Cereb Blood Flow Metab
, vol.16
, pp. 1079-1089
-
-
Bittar, P.G.1
Charnay, Y.2
Pellerin, L.3
Bouras, C.4
Magistretti, P.J.5
-
11
-
-
84861819258
-
Malonyl-CoA: the regulator of fatty acid synthesis and oxidation
-
COI: 1:CAS:528:DC%2BC38XosFartbY%3D, PID: 22833869
-
Foster DW (2012) Malonyl-CoA: the regulator of fatty acid synthesis and oxidation. J Clin Investig 122:1958–1959
-
(2012)
J Clin Investig
, vol.122
, pp. 1958-1959
-
-
Foster, D.W.1
-
12
-
-
79954988524
-
Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells
-
COI: 1:CAS:528:DC%2BC3MXls1Ohur4%3D, PID: 21395585
-
Mitchell RW, On NH, Del Bigio MR, Miller DW, Hatch GM (2011) Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells. J Neurochem 117:735–746
-
(2011)
J Neurochem
, vol.117
, pp. 735-746
-
-
Mitchell, R.W.1
On, N.H.2
Del Bigio, M.R.3
Miller, D.W.4
Hatch, G.M.5
-
13
-
-
33750110683
-
Fuel metabolism in starvation
-
COI: 1:CAS:528:DC%2BD28Xpt1Clsbw%3D, PID: 16848698
-
Cahill GF Jr (2006) Fuel metabolism in starvation. Annu Rev Nutr 26:1–22
-
(2006)
Annu Rev Nutr
, vol.26
, pp. 1-22
-
-
Cahill, G.F.1
-
14
-
-
84858782079
-
AMPK: a nutrient and energy sensor that maintains energy homeostasis
-
COI: 1:CAS:528:DC%2BC38XksVenu7w%3D, PID: 22436748
-
Hardie DG, Ross FA, Hawley SA (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13:251–262
-
(2012)
Nat Rev Mol Cell Biol
, vol.13
, pp. 251-262
-
-
Hardie, D.G.1
Ross, F.A.2
Hawley, S.A.3
-
16
-
-
77649271004
-
Effects of AMP-activated protein kinase in cerebral ischemia
-
COI: 1:CAS:528:DC%2BC3cXisF2htbs%3D, PID: 20010958
-
Li J, McCullough LD (2010) Effects of AMP-activated protein kinase in cerebral ischemia. J Cereb Blood Flow Metab 30:480–492
-
(2010)
J Cereb Blood Flow Metab
, vol.30
, pp. 480-492
-
-
Li, J.1
McCullough, L.D.2
-
17
-
-
84855993170
-
Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease
-
COI: 1:CAS:528:DC%2BC38XhsVOgtLs%3D, PID: 22262909
-
Lim MA, Selak MA, Xiang Z, Krainc D, Neve RL, Kraemer BC, Watts JL, Kalb RG (2012) Reduced activity of AMP-activated protein kinase protects against genetic models of motor neuron disease. J Neurosci 32:1123–1141
-
(2012)
J Neurosci
, vol.32
, pp. 1123-1141
-
-
Lim, M.A.1
Selak, M.A.2
Xiang, Z.3
Krainc, D.4
Neve, R.L.5
Kraemer, B.C.6
Watts, J.L.7
Kalb, R.G.8
-
18
-
-
38449089413
-
AMP-activated protein kinase: how a mistake in energy gauge causes glycogen storage
-
Ofir M, Hochhauser E, Vidne BA, Freimark D, Arad M (2007) AMP-activated protein kinase: how a mistake in energy gauge causes glycogen storage. Harefuah 146:770–775, 813–814
-
(2007)
Harefuah 146:770–775
, pp. 813-814
-
-
Ofir, M.1
Hochhauser, E.2
Vidne, B.A.3
Freimark, D.4
Arad, M.5
-
19
-
-
64349115078
-
AMPK in the brain: its roles in energy balance and neuroprotection
-
COI: 1:CAS:528:DC%2BD1MXlsFyks7c%3D, PID: 19393004
-
Ronnett GV, Ramamurthy S, Kleman AM, Landree LE, Aja S (2009) AMPK in the brain: its roles in energy balance and neuroprotection. J Neurochem 109(Suppl 1):17–23
-
(2009)
J Neurochem
, vol.109
, pp. 17-23
-
-
Ronnett, G.V.1
Ramamurthy, S.2
Kleman, A.M.3
Landree, L.E.4
Aja, S.5
-
20
-
-
70349973869
-
Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy
-
COI: 1:CAS:528:DC%2BD1MXhtFOktLfJ, PID: 19644919
-
Poels J, Spasic MR, Callaerts P, Norga KK (2009) Expanding roles for AMP-activated protein kinase in neuronal survival and autophagy. BioEssays 31:944–952
-
(2009)
BioEssays
, vol.31
, pp. 944-952
-
-
Poels, J.1
Spasic, M.R.2
Callaerts, P.3
Norga, K.K.4
-
21
-
-
0037056373
-
Premorbid weight, body mass, and varsity athletics in ALS
-
COI: 1:STN:280:DC%2BD38vmt1elsw%3D%3D, PID: 12221178
-
Scarmeas N, Shih T, Stern Y, Ottman R, Rowland LP (2002) Premorbid weight, body mass, and varsity athletics in ALS. Neurology 59:773–775
-
(2002)
Neurology
, vol.59
, pp. 773-775
-
-
Scarmeas, N.1
Shih, T.2
Stern, Y.3
Ottman, R.4
Rowland, L.P.5
-
22
-
-
61449262800
-
Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs?
-
PID: 19185883
-
Vaisman N, Lusaus M, Nefussy B, Niv E, Comaneshter D, Hallack R, Drory VE (2009) Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs? J Neurol Sci 279:26–29
-
(2009)
J Neurol Sci
, vol.279
, pp. 26-29
-
-
Vaisman, N.1
Lusaus, M.2
Nefussy, B.3
Niv, E.4
Comaneshter, D.5
Hallack, R.6
Drory, V.E.7
-
23
-
-
0034875640
-
Factors correlated with hypermetabolism in patients with amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD3MXms12hurs%3D, PID: 11522556
-
Desport JC, Preux PM, Magy L, Boirie Y, Vallat JM, Beaufrere B, Couratier P (2001) Factors correlated with hypermetabolism in patients with amyotrophic lateral sclerosis. Am J Clin Nutr 74:328–334
-
(2001)
Am J Clin Nutr
, vol.74
, pp. 328-334
-
-
Desport, J.C.1
Preux, P.M.2
Magy, L.3
Boirie, Y.4
Vallat, J.M.5
Beaufrere, B.6
Couratier, P.7
-
24
-
-
0033595524
-
Nutritional status is a prognostic factor for survival in ALS patients
-
COI: 1:STN:280:DyaK1MvisVGrtw%3D%3D, PID: 10496266
-
Desport JC, Preux PM, Truong TC, Vallat JM, Sautereau D, Couratier P (1999) Nutritional status is a prognostic factor for survival in ALS patients. Neurology 53:1059–1063
-
(1999)
Neurology
, vol.53
, pp. 1059-1063
-
-
Desport, J.C.1
Preux, P.M.2
Truong, T.C.3
Vallat, J.M.4
Sautereau, D.5
Couratier, P.6
-
25
-
-
78649368924
-
A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS
-
PID: 20500116
-
Jawaid A, Murthy SB, Wilson AM, Qureshi SU, Amro MJ, Wheaton M, Simpson E, Harati Y, Strutt AM, York MK, Schulz PE (2010) A decrease in body mass index is associated with faster progression of motor symptoms and shorter survival in ALS. Amyotroph Lateral Scler 11:542–548
-
(2010)
Amyotroph Lateral Scler
, vol.11
, pp. 542-548
-
-
Jawaid, A.1
Murthy, S.B.2
Wilson, A.M.3
Qureshi, S.U.4
Amro, M.J.5
Wheaton, M.6
Simpson, E.7
Harati, Y.8
Strutt, A.M.9
York, M.K.10
Schulz, P.E.11
-
26
-
-
0030042365
-
Nutritional status of patients with amyotrophic lateral sclerosis: relation to the proximity of death
-
COI: 1:STN:280:DyaK287ht1OrtQ%3D%3D, PID: 8604660
-
Kasarskis EJ, Berryman S, Vanderleest JG, Schneider AR, McClain CJ (1996) Nutritional status of patients with amyotrophic lateral sclerosis: relation to the proximity of death. Am J Clin Nutr 63:130–137
-
(1996)
Am J Clin Nutr
, vol.63
, pp. 130-137
-
-
Kasarskis, E.J.1
Berryman, S.2
Vanderleest, J.G.3
Schneider, A.R.4
McClain, C.J.5
-
27
-
-
68349157123
-
Hypermetabolism in ALS patients: an early and persistent phenomenon
-
COI: 1:CAS:528:DC%2BD1MXpsVegt78%3D, PID: 19306035
-
Bouteloup C, Desport JC, Clavelou P, Guy N, Derumeaux-Burel H, Ferrier A, Couratier P (2009) Hypermetabolism in ALS patients: an early and persistent phenomenon. J Neurol 256:1236–1242
-
(2009)
J Neurol
, vol.256
, pp. 1236-1242
-
-
Bouteloup, C.1
Desport, J.C.2
Clavelou, P.3
Guy, N.4
Derumeaux-Burel, H.5
Ferrier, A.6
Couratier, P.7
-
28
-
-
78650023926
-
Energy metabolism in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3cXhsFCru7nF, PID: 21035400
-
Dupuis L, Pradat P-F, Ludolph AC, Loeffler J-P (2011) Energy metabolism in amyotrophic lateral sclerosis. Lancet Neurol 10:75–82
-
(2011)
Lancet Neurol
, vol.10
, pp. 75-82
-
-
Dupuis, L.1
Pradat, P.-F.2
Ludolph, A.C.3
Loeffler, J.-P.4
-
29
-
-
84875696078
-
Premorbid body mass index and risk of amyotrophic lateral sclerosis
-
PID: 23134505
-
O’Reilly EJ, Wang H, Weisskopf MG, Fitzgerald KC, Falcone G, McCullough ML, Thun M, Park Y, Kolonel LN, Ascherio A (2013) Premorbid body mass index and risk of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Frontotemporal Degener 14:205–211
-
(2013)
Amyotroph Lateral Scler Frontotemporal Degener
, vol.14
, pp. 205-211
-
-
O’Reilly, E.J.1
Wang, H.2
Weisskopf, M.G.3
Fitzgerald, K.C.4
Falcone, G.5
McCullough, M.L.6
Thun, M.7
Park, Y.8
Kolonel, L.N.9
Ascherio, A.10
-
30
-
-
33744816556
-
Hypermetabolism in ALS: correlations with clinical and paraclinical parameters
-
Desport J-C, Torny F, Lacoste M, Preux P-M, Couratier P (2005) Hypermetabolism in ALS: correlations with clinical and paraclinical parameters. Neuro Degener Dis 2:202–207
-
(2005)
Neuro Degener Dis
, vol.2
, pp. 202-207
-
-
Desport, J.-C.1
Torny, F.2
Lacoste, M.3
Preux, P.-M.4
Couratier, P.5
-
31
-
-
0013911740
-
Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis
-
COI: 1:STN:280:DyaF287jsFaisA%3D%3D, PID: 5949060
-
Afifi AK, Aleu FP, Goodgold J, MacKay B (1966) Ultrastructure of atrophic muscle in amyotrophic lateral sclerosis. Neurology 16:475–481
-
(1966)
Neurology
, vol.16
, pp. 475-481
-
-
Afifi, A.K.1
Aleu, F.P.2
Goodgold, J.3
MacKay, B.4
-
32
-
-
0019845220
-
The ultrastructure of intramuscular nerves in amyotrophic lateral sclerosis
-
COI: 1:STN:280:DyaL3s7it12qsA%3D%3D, PID: 7349578
-
Atsumi T (1981) The ultrastructure of intramuscular nerves in amyotrophic lateral sclerosis. Acta Neuropathol 55:193–198
-
(1981)
Acta Neuropathol
, vol.55
, pp. 193-198
-
-
Atsumi, T.1
-
33
-
-
0030019414
-
Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK28XhtlKhs7Y%3D, PID: 8929976
-
Sasaki S, Iwata M (1996) Ultrastructural study of synapses in the anterior horn neurons of patients with amyotrophic lateral sclerosis. Neurosci Lett 204:53–56
-
(1996)
Neurosci Lett
, vol.204
, pp. 53-56
-
-
Sasaki, S.1
Iwata, M.2
-
34
-
-
0030026832
-
Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis
-
COI: 1:STN:280:DyaK287psl2ntg%3D%3D, PID: 8967752
-
Siklos L, Engelhardt J, Harati Y, Smith RG, Joo F, Appel SH (1996) Ultrastructural evidence for altered calcium in motor nerve terminals in amyotropic lateral sclerosis. Ann Neurol 39:203–216
-
(1996)
Ann Neurol
, vol.39
, pp. 203-216
-
-
Siklos, L.1
Engelhardt, J.2
Harati, Y.3
Smith, R.G.4
Joo, F.5
Appel, S.H.6
-
35
-
-
0032745071
-
Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death
-
COI: 1:CAS:528:DyaK1MXns1Crtb0%3D, PID: 10553999
-
Borthwick GM, Johnson MA, Ince PG, Shaw PJ, Turnbull DM (1999) Mitochondrial enzyme activity in amyotrophic lateral sclerosis: implications for the role of mitochondria in neuronal cell death. Ann neurol 46:787–790
-
(1999)
Ann neurol
, vol.46
, pp. 787-790
-
-
Borthwick, G.M.1
Johnson, M.A.2
Ince, P.G.3
Shaw, P.J.4
Turnbull, D.M.5
-
36
-
-
0027359334
-
Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK2cXhtVertb0%3D, PID: 8245985
-
Bowling AC, Schulz JB, Brown RH Jr, Beal MF (1993) Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis. J Neurochem 61:2322–2325
-
(1993)
J Neurochem
, vol.61
, pp. 2322-2325
-
-
Bowling, A.C.1
Schulz, J.B.2
Brown, R.H.3
Beal, M.F.4
-
37
-
-
0029744863
-
Decreased cytochrome c oxidase activity but unchanged superoxide dismutase and glutathione peroxidase activities in the spinal cords of patients with amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK28XkvFGlsLg%3D, PID: 8841988
-
Fujita K, Yamauchi M, Shibayama K, Ando M, Honda M, Nagata Y (1996) Decreased cytochrome c oxidase activity but unchanged superoxide dismutase and glutathione peroxidase activities in the spinal cords of patients with amyotrophic lateral sclerosis. J Neurosci Res 45:276–281
-
(1996)
J Neurosci Res
, vol.45
, pp. 276-281
-
-
Fujita, K.1
Yamauchi, M.2
Shibayama, K.3
Ando, M.4
Honda, M.5
Nagata, Y.6
-
38
-
-
0032539791
-
Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK1cXhsFenurc%3D, PID: 9559989
-
Wiedemann FR, Winkler K, Kuznetsov AV, Bartels C, Vielhaber S, Feistner H, Kunz WS (1998) Impairment of mitochondrial function in skeletal muscle of patients with amyotrophic lateral sclerosis. J Neurol Sci 156:65–72
-
(1998)
J Neurol Sci
, vol.156
, pp. 65-72
-
-
Wiedemann, F.R.1
Winkler, K.2
Kuznetsov, A.V.3
Bartels, C.4
Vielhaber, S.5
Feistner, H.6
Kunz, W.S.7
-
39
-
-
32644434546
-
Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: a temporal study in man
-
COI: 1:CAS:528:DC%2BD28Xhs1Snsrw%3D, PID: 16126198
-
Echaniz-Laguna A, Zoll J, Ponsot E, N’Guessan B, Tranchant C, Loeffler J-P, Lampert E (2006) Muscular mitochondrial function in amyotrophic lateral sclerosis is progressively altered as the disease develops: a temporal study in man. Exp Neurol 198:25–30
-
(2006)
Exp Neurol
, vol.198
, pp. 25-30
-
-
Echaniz-Laguna, A.1
Zoll, J.2
Ponsot, E.3
N’Guessan, B.4
Tranchant, C.5
Loeffler, J.-P.6
Lampert, E.7
-
40
-
-
84897425769
-
Preclinical research: make mouse studies work
-
PID: 24678540
-
Perrin S (2014) Preclinical research: make mouse studies work. Nature 507:423–425
-
(2014)
Nature
, vol.507
, pp. 423-425
-
-
Perrin, S.1
-
41
-
-
0018352279
-
Endocrinologic regulation of carbohydrate metabolism. Amyotrophic lateral sclerosis and parkinsonism-dementia on guam
-
COI: 1:STN:280:DyaE1M7ksVansQ%3D%3D, PID: 426665
-
Nagano Y, Tsubaki T, Chase TN (1979) Endocrinologic regulation of carbohydrate metabolism. Amyotrophic lateral sclerosis and parkinsonism-dementia on guam. Arch Neurol 36:217–220
-
(1979)
Arch Neurol
, vol.36
, pp. 217-220
-
-
Nagano, Y.1
Tsubaki, T.2
Chase, T.N.3
-
42
-
-
77649312506
-
Impaired glucose tolerance in patients with amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3cXisV2msbw%3D, PID: 20184518
-
Pradat P-F, Bruneteau G, Gordon PH, Dupuis L, Bonnefont-Rousselot D, Simon D, Salachas F, Corcia P, Frochot V, Lacorte J-M, Jardel C, Coussieu C, Le Forestier N, Lacomblez L, Loeffler J-P, Meininger V (2010) Impaired glucose tolerance in patients with amyotrophic lateral sclerosis. Amyotroph Lateral Scler 11:166–171
-
(2010)
Amyotroph Lateral Scler
, vol.11
, pp. 166-171
-
-
Pradat, P.-F.1
Bruneteau, G.2
Gordon, P.H.3
Dupuis, L.4
Bonnefont-Rousselot, D.5
Simon, D.6
Salachas, F.7
Corcia, P.8
Frochot, V.9
Lacorte, J.-M.10
Jardel, C.11
Coussieu, C.12
Le Forestier, N.13
Lacomblez, L.14
Loeffler, J.-P.15
Meininger, V.16
-
43
-
-
0021257036
-
Insulin resistance in amyotrophic lateral sclerosis
-
COI: 1:STN:280:DyaL2c3hsFWmsQ%3D%3D, PID: 6374040
-
Reyes ET, Perurena OH, Festoff BW, Jorgensen R, Moore WV (1984) Insulin resistance in amyotrophic lateral sclerosis. J Neurol Sci 63:317–324
-
(1984)
J Neurol Sci
, vol.63
, pp. 317-324
-
-
Reyes, E.T.1
Perurena, O.H.2
Festoff, B.W.3
Jorgensen, R.4
Moore, W.V.5
-
44
-
-
18044366164
-
The metabolic hypothesis in amyotrophic lateral sclerosis: insights from mutant Cu/Zn-superoxide dismutase mice
-
COI: 1:CAS:528:DC%2BD2MXjs1Kmt7o%3D, PID: 15862714
-
Gonzalez de Aguilar J-L, Dupuis L, Oudart H, Loeffler J-P (2005) The metabolic hypothesis in amyotrophic lateral sclerosis: insights from mutant Cu/Zn-superoxide dismutase mice. Biomed Pharmacother 59:190–196
-
(2005)
Biomed Pharmacother
, vol.59
, pp. 190-196
-
-
Gonzalez de Aguilar, J.-L.1
Dupuis, L.2
Oudart, H.3
Loeffler, J.-P.4
-
45
-
-
0023636605
-
Lowered cerebral glucose utilization in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaL1cXltlOmtw%3D%3D, PID: 3501273
-
Dalakas MC, Hatazawa J, Brooks RA, Di Chiro G (1987) Lowered cerebral glucose utilization in amyotrophic lateral sclerosis. Ann neurol 22:580–586
-
(1987)
Ann neurol
, vol.22
, pp. 580-586
-
-
Dalakas, M.C.1
Hatazawa, J.2
Brooks, R.A.3
Di Chiro, G.4
-
46
-
-
84879528008
-
Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis
-
COI: 1:CAS:528:DC%2BC3sXhtFejs7nO, PID: 23754387
-
Dodge JC, Treleaven CM, Fidler JA, Tamsett TJ, Bao C, Searles M, Taksir TV, Misra K, Sidman RL, Cheng SH, Shihabuddin LS (2013) Metabolic signatures of amyotrophic lateral sclerosis reveal insights into disease pathogenesis. Proc Natl Acad Sci USA 110:10812–10817
-
(2013)
Proc Natl Acad Sci USA
, vol.110
, pp. 10812-10817
-
-
Dodge, J.C.1
Treleaven, C.M.2
Fidler, J.A.3
Tamsett, T.J.4
Bao, C.5
Searles, M.6
Taksir, T.V.7
Misra, K.8
Sidman, R.L.9
Cheng, S.H.10
Shihabuddin, L.S.11
-
47
-
-
0020639648
-
Abnormalities of lipoprotein and carbohydrate metabolism in degenerative diseases of the nervous system—motor neuron disease and spinocerebellar degeneration
-
COI: 1:STN:280:DyaL3s3kvF2ksA%3D%3D, PID: 6346585
-
Murai A, Miyahara T, Tanaka T, Kaneko T, Sako Y, Kameyama M (1983) Abnormalities of lipoprotein and carbohydrate metabolism in degenerative diseases of the nervous system—motor neuron disease and spinocerebellar degeneration. Tohoku J Exp Med 139:365–376
-
(1983)
Tohoku J Exp Med
, vol.139
, pp. 365-376
-
-
Murai, A.1
Miyahara, T.2
Tanaka, T.3
Kaneko, T.4
Sako, Y.5
Kameyama, M.6
-
48
-
-
77950870713
-
ALS disease onset may occur later in patients with pre-morbid diabetes mellitus
-
COI: 1:STN:280:DC%2BC3czpsVKkug%3D%3D, PID: 20074230
-
Jawaid A, Salamone AR, Strutt AM, Murthy SB, Wheaton M, McDowell EJ, Simpson E, Appel SH, York MK, Schulz PE (2010) ALS disease onset may occur later in patients with pre-morbid diabetes mellitus. Eur J Neurol 17:733–739
-
(2010)
Eur J Neurol
, vol.17
, pp. 733-739
-
-
Jawaid, A.1
Salamone, A.R.2
Strutt, A.M.3
Murthy, S.B.4
Wheaton, M.5
McDowell, E.J.6
Simpson, E.7
Appel, S.H.8
York, M.K.9
Schulz, P.E.10
-
49
-
-
41349122697
-
Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD1cXjs1Kjtro%3D, PID: 18199832
-
Dupuis L, Corcia P, Fergani A, Gonzalez De Aguilar JL, Bonnefont-Rousselot D, Bittar R, Seilhean D, Hauw JJ, Lacomblez L, Loeffler JP, Meininger V (2008) Dyslipidemia is a protective factor in amyotrophic lateral sclerosis. Neurology 70:1004–1009
-
(2008)
Neurology
, vol.70
, pp. 1004-1009
-
-
Dupuis, L.1
Corcia, P.2
Fergani, A.3
Gonzalez De Aguilar, J.L.4
Bonnefont-Rousselot, D.5
Bittar, R.6
Seilhean, D.7
Hauw, J.J.8
Lacomblez, L.9
Loeffler, J.P.10
Meininger, V.11
-
50
-
-
79953817635
-
Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3MXjvVOrtL0%3D, PID: 21128082
-
Dorst J, Kuhnlein P, Hendrich C, Kassubek J, Sperfeld AD, Ludolph AC (2011) Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis. J Neurol 258:613–617
-
(2011)
J Neurol
, vol.258
, pp. 613-617
-
-
Dorst, J.1
Kuhnlein, P.2
Hendrich, C.3
Kassubek, J.4
Sperfeld, A.D.5
Ludolph, A.C.6
-
51
-
-
15044342282
-
Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players
-
PID: 15634730
-
Chio A, Benzi G, Dossena M, Mutani R, Mora G (2005) Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players. Brain 128:472–476
-
(2005)
Brain
, vol.128
, pp. 472-476
-
-
Chio, A.1
Benzi, G.2
Dossena, M.3
Mutani, R.4
Mora, G.5
-
52
-
-
0037046183
-
APOE: a potential marker of disease progression in ALS
-
COI: 1:CAS:528:DC%2BD38XjtlCiu7g%3D, PID: 11940705
-
Lacomblez L, Doppler V, Beucler I, Costes G, Salachas F, Raisonnier A, Le Forestier N, Pradat PF, Bruckert E, Meininger V (2002) APOE: a potential marker of disease progression in ALS. Neurology 58:1112–1114
-
(2002)
Neurology
, vol.58
, pp. 1112-1114
-
-
Lacomblez, L.1
Doppler, V.2
Beucler, I.3
Costes, G.4
Salachas, F.5
Raisonnier, A.6
Le Forestier, N.7
Pradat, P.F.8
Bruckert, E.9
Meininger, V.10
-
53
-
-
48249090462
-
Are statin medications safe in patients with ALS?
-
COI: 1:CAS:528:DC%2BD1cXos12iurg%3D, PID: 18608105
-
Zinman L, Sadeghi R, Gawel M, Patton D, Kiss A (2008) Are statin medications safe in patients with ALS? Amyotroph Lateral Scler 9:223–228
-
(2008)
Amyotroph Lateral Scler
, vol.9
, pp. 223-228
-
-
Zinman, L.1
Sadeghi, R.2
Gawel, M.3
Patton, D.4
Kiss, A.5
-
54
-
-
57649218663
-
An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA’s spontaneous adverse event reporting system
-
PID: 18821724
-
Colman E, Szarfman A, Wyeth J, Mosholder A, Jillapalli D, Levine J, Avigan M (2008) An evaluation of a data mining signal for amyotrophic lateral sclerosis and statins detected in FDA’s spontaneous adverse event reporting system. Pharmacoepidemiol Drug Saf 17:1068–1076
-
(2008)
Pharmacoepidemiol Drug Saf
, vol.17
, pp. 1068-1076
-
-
Colman, E.1
Szarfman, A.2
Wyeth, J.3
Mosholder, A.4
Jillapalli, D.5
Levine, J.6
Avigan, M.7
-
55
-
-
84879514688
-
Adipose tissue distribution predicts survival in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3sXhtFahsr3J, PID: 23826340
-
Lindauer E, Dupuis L, Müller HP, Neumann H, Ludolph AC, Kassubek J (2013) Adipose tissue distribution predicts survival in amyotrophic lateral sclerosis. PLoS One 8:e67783
-
(2013)
PLoS One
, vol.8
, pp. e67783
-
-
Lindauer, E.1
Dupuis, L.2
Müller, H.P.3
Neumann, H.4
Ludolph, A.C.5
Kassubek, J.6
-
56
-
-
84861885929
-
The critical role of metabolic pathways in aging
-
COI: 1:CAS:528:DC%2BC38XotlGqtLo%3D, PID: 22618766
-
Barzilai N, Huffman DM, Muzumdar RH, Bartke A (2012) The critical role of metabolic pathways in aging. Diabetes 61:1315–1322
-
(2012)
Diabetes
, vol.61
, pp. 1315-1322
-
-
Barzilai, N.1
Huffman, D.M.2
Muzumdar, R.H.3
Bartke, A.4
-
57
-
-
0017237184
-
Antecedent events in amyotrophic lateral sclerosis
-
COI: 1:STN:280:DyaE287is1Knug%3D%3D, PID: 946326
-
Felmus MT, Patten BM, Swanke L (1976) Antecedent events in amyotrophic lateral sclerosis. Neurology 26:167–172
-
(1976)
Neurology
, vol.26
, pp. 167-172
-
-
Felmus, M.T.1
Patten, B.M.2
Swanke, L.3
-
58
-
-
0029846389
-
Physical activity, trauma, and ALS: a case-control study
-
COI: 1:STN:280:DyaK2s%2FivVGrsg%3D%3D, PID: 8874593
-
Strickland D, Smith SA, Dolliff G, Goldman L, Roelofs RI (1996) Physical activity, trauma, and ALS: a case-control study. Acta Neurol Scand 94:45–50
-
(1996)
Acta Neurol Scand
, vol.94
, pp. 45-50
-
-
Strickland, D.1
Smith, S.A.2
Dolliff, G.3
Goldman, L.4
Roelofs, R.I.5
-
59
-
-
12544253253
-
Physical activity and the association with sporadic ALS
-
COI: 1:STN:280:DC%2BD2M%2FktFSntQ%3D%3D, PID: 15668420
-
Veldink JH, Kalmijn S, Groeneveld GJ, Titulaer MJ, Wokke JHJ, van den Berg LH (2005) Physical activity and the association with sporadic ALS. Neurology 64:241–245
-
(2005)
Neurology
, vol.64
, pp. 241-245
-
-
Veldink, J.H.1
Kalmijn, S.2
Groeneveld, G.J.3
Titulaer, M.J.4
Wokke, J.H.J.5
van den Berg, L.H.6
-
60
-
-
34548588613
-
Sports and trauma in amyotrophic lateral sclerosis revisited
-
PID: 17681549
-
Armon C (2007) Sports and trauma in amyotrophic lateral sclerosis revisited. J Neurol Sci 262:45–53
-
(2007)
J Neurol Sci
, vol.262
, pp. 45-53
-
-
Armon, C.1
-
61
-
-
0025909838
-
Hypotheses to explain the association between vigorous physical activity and amyotrophic lateral sclerosis
-
COI: 1:STN:280:DyaK3M3ltFOqsw%3D%3D, PID: 2041488
-
Longstreth WT, Nelson LM, Koepsell TD, van Belle G (1991) Hypotheses to explain the association between vigorous physical activity and amyotrophic lateral sclerosis. Med Hypotheses 34:144–148
-
(1991)
Med Hypotheses
, vol.34
, pp. 144-148
-
-
Longstreth, W.T.1
Nelson, L.M.2
Koepsell, T.D.3
van Belle, G.4
-
62
-
-
34249913730
-
A randomized controlled trial of resistance exercise in individuals with ALS
-
PID: 17548549
-
Bello-Haas VD, Florence JM, Kloos AD, Scheirbecker J, Lopate G, Hayes SM, Pioro EP, Mitsumoto H (2007) A randomized controlled trial of resistance exercise in individuals with ALS. Neurology 68:2003–2007
-
(2007)
Neurology
, vol.68
, pp. 2003-2007
-
-
Bello-Haas, V.D.1
Florence, J.M.2
Kloos, A.D.3
Scheirbecker, J.4
Lopate, G.5
Hayes, S.M.6
Pioro, E.P.7
Mitsumoto, H.8
-
63
-
-
0035886628
-
The value of muscle exercise in patients with amyotrophic lateral sclerosis
-
COI: 1:STN:280:DC%2BD3Mnkt1Kqtg%3D%3D, PID: 11677004
-
Drory VE, Goltsman E, Reznik JG, Mosek A, Korczyn AD (2001) The value of muscle exercise in patients with amyotrophic lateral sclerosis. J Neurol Sci 191:133–137
-
(2001)
J Neurol Sci
, vol.191
, pp. 133-137
-
-
Drory, V.E.1
Goltsman, E.2
Reznik, J.G.3
Mosek, A.4
Korczyn, A.D.5
-
64
-
-
84947021652
-
Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease
-
PID: 26152932
-
Vergouts M, Marinangeli C, Ingelbrecht C, Genard G, Schakman O, Sternotte A, Calas A, Hermans E (2015) Early ALS-type gait abnormalities in AMP-dependent protein kinase-deficient mice suggest a role for this metabolic sensor in early stages of the disease. Metab Brain Dis. doi:10.1007/s11011-015-9706-9
-
(2015)
Metab Brain Dis
-
-
Vergouts, M.1
Marinangeli, C.2
Ingelbrecht, C.3
Genard, G.4
Schakman, O.5
Sternotte, A.6
Calas, A.7
Hermans, E.8
-
65
-
-
84874950486
-
Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration
-
COI: 1:CAS:528:DC%2BC3sXjvVaqsL0%3D, PID: 23306556
-
Behan AT, Breen B, Hogg M, Woods I, Coughlan K, Mitchem M, Prehn JH (2013) Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration. Cell Death Differ 20:589–598
-
(2013)
Cell Death Differ
, vol.20
, pp. 589-598
-
-
Behan, A.T.1
Breen, B.2
Hogg, M.3
Woods, I.4
Coughlan, K.5
Mitchem, M.6
Prehn, J.H.7
-
66
-
-
84906838269
-
Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC2cXhslaltrjI, PID: 24833719
-
Lim MA, Bence KK, Sandesara I, Andreux P, Auwerx J, Ishibashi J, Seale P, Kalb RG (2014) Genetically altering organismal metabolism by leptin-deficiency benefits a mouse model of amyotrophic lateral sclerosis. Hum Mol Genet 23:4995–5008
-
(2014)
Hum Mol Genet
, vol.23
, pp. 4995-5008
-
-
Lim, M.A.1
Bence, K.K.2
Sandesara, I.3
Andreux, P.4
Auwerx, J.5
Ishibashi, J.6
Seale, P.7
Kalb, R.G.8
-
67
-
-
84881587124
-
PGC-1alpha is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3sXht1CktLvP, PID: 23669350
-
Eschbach J, Schwalenstocker B, Soyal SM, Bayer H, Wiesner D, Akimoto C, Nilsson A-C, Birve A, Meyer T, Dupuis L, Danzer KM, Andersen PM, Witting A, Ludolph AC, Patsch W, Weydt P (2013) PGC-1alpha is a male-specific disease modifier of human and experimental amyotrophic lateral sclerosis. Hum Mol Genet 22:3477–3484
-
(2013)
Hum Mol Genet
, vol.22
, pp. 3477-3484
-
-
Eschbach, J.1
Schwalenstocker, B.2
Soyal, S.M.3
Bayer, H.4
Wiesner, D.5
Akimoto, C.6
Nilsson, A.-C.7
Birve, A.8
Meyer, T.9
Dupuis, L.10
Danzer, K.M.11
Andersen, P.M.12
Witting, A.13
Ludolph, A.C.14
Patsch, W.15
Weydt, P.16
-
68
-
-
81555206662
-
PGC-1alpha protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model
-
COI: 1:CAS:528:DC%2BC3MXhsVOqurbM, PID: 22102466
-
Liang H, Ward WF, Jang YC, Bhattacharya A, Bokov AF, Li Y, Jernigan A, Richardson A, Van Remmen H (2011) PGC-1alpha protects neurons and alters disease progression in an amyotrophic lateral sclerosis mouse model. Muscle Nerve 44:947–956
-
(2011)
Muscle Nerve
, vol.44
, pp. 947-956
-
-
Liang, H.1
Ward, W.F.2
Jang, Y.C.3
Bhattacharya, A.4
Bokov, A.F.5
Li, Y.6
Jernigan, A.7
Richardson, A.8
Van Remmen, H.9
-
69
-
-
84860458565
-
Elevated PGC-1alpha activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS
-
PID: 22560226
-
Da Cruz S, Parone PA, Lopes VS, Lillo C, McAlonis-Downes M, Lee SK, Vetto AP, Petrosyan S, Marsala M, Murphy AN, Williams DS, Spiegelman BM, Cleveland DW (2012) Elevated PGC-1alpha activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab 15:778–786
-
(2012)
Cell Metab
, vol.15
, pp. 778-786
-
-
Da Cruz, S.1
Parone, P.A.2
Lopes, V.S.3
Lillo, C.4
McAlonis-Downes, M.5
Lee, S.K.6
Vetto, A.P.7
Petrosyan, S.8
Marsala, M.9
Murphy, A.N.10
Williams, D.S.11
Spiegelman, B.M.12
Cleveland, D.W.13
-
70
-
-
79960560886
-
Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1alpha) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3MXhtVGhtLfO, PID: 21771318
-
Zhao W, Varghese M, Yemul S, Pan Y, Cheng A, Marano P, Hassan S, Vempati P, Chen F, Qian X, Pasinetti GM (2011) Peroxisome proliferator activator receptor gamma coactivator-1alpha (PGC-1alpha) improves motor performance and survival in a mouse model of amyotrophic lateral sclerosis. Mol Neurodegener 6:51
-
(2011)
Mol Neurodegener
, vol.6
, pp. 51
-
-
Zhao, W.1
Varghese, M.2
Yemul, S.3
Pan, Y.4
Cheng, A.5
Marano, P.6
Hassan, S.7
Vempati, P.8
Chen, F.9
Qian, X.10
Pasinetti, G.M.11
-
71
-
-
65549128133
-
Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons
-
PID: 19404401
-
Dupuis L, Gonzalez de Aguilar JL, Echaniz-Laguna A, Eschbach J, Rene F, Oudart H, Halter B, Huze C, Schaeffer L, Bouillaud F, Loeffler JP (2009) Muscle mitochondrial uncoupling dismantles neuromuscular junction and triggers distal degeneration of motor neurons. PLoS One 4:e5390
-
(2009)
PLoS One
, vol.4
, pp. e5390
-
-
Dupuis, L.1
Gonzalez de Aguilar, J.L.2
Echaniz-Laguna, A.3
Eschbach, J.4
Rene, F.5
Oudart, H.6
Halter, B.7
Huze, C.8
Schaeffer, L.9
Bouillaud, F.10
Loeffler, J.P.11
-
72
-
-
84887340065
-
UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC3sXhvV2qurvJ, PID: 24141050
-
Peixoto PM, Kim H-J, Sider B, Starkov A, Horvath TL, Manfredi G (2013) UCP2 overexpression worsens mitochondrial dysfunction and accelerates disease progression in a mouse model of amyotrophic lateral sclerosis. Mol Cell Neurosci 57:104–110
-
(2013)
Mol Cell Neurosci
, vol.57
, pp. 104-110
-
-
Peixoto, P.M.1
Kim, H.-J.2
Sider, B.3
Starkov, A.4
Horvath, T.L.5
Manfredi, G.6
-
73
-
-
0033606410
-
No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice
-
COI: 1:CAS:528:DyaK1MXkt1CrsbY%3D, PID: 10375685
-
Pedersen WA, Mattson MP (1999) No benefit of dietary restriction on disease onset or progression in amyotrophic lateral sclerosis Cu/Zn-superoxide dismutase mutant mice. Brain Res 833:117–120
-
(1999)
Brain Res
, vol.833
, pp. 117-120
-
-
Pedersen, W.A.1
Mattson, M.P.2
-
74
-
-
13244256829
-
Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse
-
COI: 1:CAS:528:DC%2BD2MXitFWnt7c%3D, PID: 15625688
-
Hamadeh MJ, Rodriguez MC, Kaczor JJ, Tarnopolsky MA (2005) Caloric restriction transiently improves motor performance but hastens clinical onset of disease in the Cu/Zn-superoxide dismutase mutant G93A mouse. Muscle Nerve 31:214–220
-
(2005)
Muscle Nerve
, vol.31
, pp. 214-220
-
-
Hamadeh, M.J.1
Rodriguez, M.C.2
Kaczor, J.J.3
Tarnopolsky, M.A.4
-
75
-
-
33845290591
-
Transient caloric restriction in early adulthood hastens disease endpoint in male, but not female, Cu/Zn-SOD mutant G93A mice
-
COI: 1:CAS:528:DC%2BD2sXislOltQ%3D%3D, PID: 16941656
-
Hamadeh MJ, Tarnopolsky MA (2006) Transient caloric restriction in early adulthood hastens disease endpoint in male, but not female, Cu/Zn-SOD mutant G93A mice. Muscle Nerve 34:709–719
-
(2006)
Muscle Nerve
, vol.34
, pp. 709-719
-
-
Hamadeh, M.J.1
Tarnopolsky, M.A.2
-
76
-
-
77949752957
-
Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS
-
PID: 20195368
-
Patel BP, Safdar A, Raha S, Tarnopolsky MA, Hamadeh MJ (2010) Caloric restriction shortens lifespan through an increase in lipid peroxidation, inflammation and apoptosis in the G93A mouse, an animal model of ALS. PLoS One 5:e9386
-
(2010)
PLoS One
, vol.5
, pp. e9386
-
-
Patel, B.P.1
Safdar, A.2
Raha, S.3
Tarnopolsky, M.A.4
Hamadeh, M.J.5
-
77
-
-
84861898911
-
Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS
-
COI: 1:CAS:528:DC%2BC38XotFakt74%3D, PID: 21763036
-
Bhattacharya A, Bokov A, Muller FL, Jernigan AL, Maslin K, Diaz V, Richardson A, Van Remmen H (2012) Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS. Neurobiol Aging 33:1829–1832
-
(2012)
Neurobiol Aging
, vol.33
, pp. 1829-1832
-
-
Bhattacharya, A.1
Bokov, A.2
Muller, F.L.3
Jernigan, A.L.4
Maslin, K.5
Diaz, V.6
Richardson, A.7
Van Remmen, H.8
-
78
-
-
84868674676
-
Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease
-
COI: 1:CAS:528:DC%2BC38XhslCju7rP, PID: 23145119
-
Zhao W, Varghese M, Vempati P, Dzhun A, Cheng A, Wang J, Lange D, Bilski A, Faravelli I, Pasinetti GM (2012) Caprylic triglyceride as a novel therapeutic approach to effectively improve the performance and attenuate the symptoms due to the motor neuron loss in ALS disease. PLoS One 7:e49191
-
(2012)
PLoS One
, vol.7
, pp. e49191
-
-
Zhao, W.1
Varghese, M.2
Vempati, P.3
Dzhun, A.4
Cheng, A.5
Wang, J.6
Lange, D.7
Bilski, A.8
Faravelli, I.9
Pasinetti, G.M.10
-
79
-
-
0033051815
-
Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DyaK1MXhsVSrtr4%3D, PID: 10086395
-
Klivenyi P, Ferrante RJ, Matthews RT, Bogdanov MB, Klein AM, Andreassen OA, Mueller G, Wermer M, Kaddurah-Daouk R, Beal MF (1999) Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis. Nat Med 5:347–350
-
(1999)
Nat Med
, vol.5
, pp. 347-350
-
-
Klivenyi, P.1
Ferrante, R.J.2
Matthews, R.T.3
Bogdanov, M.B.4
Klein, A.M.5
Andreassen, O.A.6
Mueller, G.7
Wermer, M.8
Kaddurah-Daouk, R.9
Beal, M.F.10
-
80
-
-
84904883028
-
Metabolic therapy with Deanna protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model
-
PID: 25061944
-
Ari C, Poff AM, Held HE, Landon CS, Goldhagen CR, Mavromates N, D’Agostino DP (2014) Metabolic therapy with Deanna protocol supplementation delays disease progression and extends survival in amyotrophic lateral sclerosis (ALS) mouse model. PLoS One 9:e103526
-
(2014)
PLoS One
, vol.9
, pp. e103526
-
-
Ari, C.1
Poff, A.M.2
Held, H.E.3
Landon, C.S.4
Goldhagen, C.R.5
Mavromates, N.6
D’Agostino, D.P.7
-
81
-
-
29244439896
-
Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x (+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride
-
COI: 1:CAS:528:DC%2BD28XhsleqsQ%3D%3D, PID: 16188953
-
Danzeisen R, Schwalenstoecker B, Gillardon F, Buerger E, Krzykalla V, Klinder K, Schild L, Hengerer B, Ludolph AC, Dorner-Ciossek C, Kussmaul L (2006) Targeted antioxidative and neuroprotective properties of the dopamine agonist pramipexole and its nondopaminergic enantiomer SND919CL2x (+)2-amino-4,5,6,7-tetrahydro-6-Lpropylamino-benzathiazole dihydrochloride. J Pharmacol Exp Ther 316:189–199
-
(2006)
J Pharmacol Exp Ther
, vol.316
, pp. 189-199
-
-
Danzeisen, R.1
Schwalenstoecker, B.2
Gillardon, F.3
Buerger, E.4
Krzykalla, V.5
Klinder, K.6
Schild, L.7
Hengerer, B.8
Ludolph, A.C.9
Dorner-Ciossek, C.10
Kussmaul, L.11
-
82
-
-
84928686083
-
Potential therapeutic drugs and methods for the treatment of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC2cXhs1Gmtr3K, PID: 24934355
-
Yacila G, Sari Y (2014) Potential therapeutic drugs and methods for the treatment of amyotrophic lateral sclerosis. Curr Med Chem 21:3583–3593
-
(2014)
Curr Med Chem
, vol.21
, pp. 3583-3593
-
-
Yacila, G.1
Sari, Y.2
-
83
-
-
84928982922
-
A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC2MXnsVWktb4%3D, PID: 25820275
-
Palamiuc L, Schlagowski A, Ngo ST, Vernay A, Dirrig-Grosch S, Henriques A, Boutillier A-L, Zoll J, Echaniz-Laguna A, Loeffler J-P, Rene F (2015) A metabolic switch toward lipid use in glycolytic muscle is an early pathologic event in a mouse model of amyotrophic lateral sclerosis. EMBO Mol Med 7:526–546
-
(2015)
EMBO Mol Med
, vol.7
, pp. 526-546
-
-
Palamiuc, L.1
Schlagowski, A.2
Ngo, S.T.3
Vernay, A.4
Dirrig-Grosch, S.5
Henriques, A.6
Boutillier, A.-L.7
Zoll, J.8
Echaniz-Laguna, A.9
Loeffler, J.-P.10
Rene, F.11
-
84
-
-
3343020674
-
Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model
-
COI: 1:CAS:528:DC%2BD2cXmsVCmtbk%3D, PID: 15263088
-
Dupuis L, Oudart H, Rene F, Gonzalez de Aguilar J-L, Loeffler J-P (2004) Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proc Natl Acad Sci USA 101:11159–11164
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 11159-11164
-
-
Dupuis, L.1
Oudart, H.2
Rene, F.3
Gonzalez de Aguilar, J.-L.4
Loeffler, J.-P.5
-
85
-
-
33745816384
-
A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis
-
PID: 16584562
-
Zhao Z, Lange DJ, Voustianiouk A, MacGrogan D, Ho L, Suh J, Humala N, Thiyagarajan M, Wang J, Pasinetti GM (2006) A ketogenic diet as a potential novel therapeutic intervention in amyotrophic lateral sclerosis. BMC Neurosci 7:29
-
(2006)
BMC Neurosci
, vol.7
, pp. 29
-
-
Zhao, Z.1
Lange, D.J.2
Voustianiouk, A.3
MacGrogan, D.4
Ho, L.5
Suh, J.6
Humala, N.7
Thiyagarajan, M.8
Wang, J.9
Pasinetti, G.M.10
-
86
-
-
84922772455
-
Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice
-
COI: 1:CAS:528:DC%2BC2cXhslGrs7rP, PID: 25443289
-
Coughlan KS, Mitchem MR, Hogg MC, Prehn JH (2015) “Preconditioning” with latrepirdine, an adenosine 5′-monophosphate-activated protein kinase activator, delays amyotrophic lateral sclerosis progression in SOD1(G93A) mice. Neurobiol Aging 36:1140–1150
-
(2015)
Neurobiol Aging
, vol.36
, pp. 1140-1150
-
-
Coughlan, K.S.1
Mitchem, M.R.2
Hogg, M.C.3
Prehn, J.H.4
-
87
-
-
80052364474
-
Metformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female mice
-
COI: 1:CAS:528:DC%2BC3MXht1WrtbzP, PID: 21909419
-
Kaneb HM, Sharp PS, Rahmani-Kondori N, Wells DJ (2011) Metformin treatment has no beneficial effect in a dose-response survival study in the SOD1(G93A) mouse model of ALS and is harmful in female mice. PLoS One 6:e24189
-
(2011)
PLoS One
, vol.6
, pp. e24189
-
-
Kaneb, H.M.1
Sharp, P.S.2
Rahmani-Kondori, N.3
Wells, D.J.4
-
88
-
-
84861581101
-
Reducing systemic hypermetabolism by inducing hypothyroidism does not prolong survival in the SOD1-G93A mouse
-
COI: 1:CAS:528:DC%2BC38XnslKitrg%3D, PID: 22424124
-
Li J, Paulson JM, Ye FD, Sung M, Hollenberg AN, Rutkove SB (2012) Reducing systemic hypermetabolism by inducing hypothyroidism does not prolong survival in the SOD1-G93A mouse. Amyotroph Lateral Scler 13:372–377
-
(2012)
Amyotroph Lateral Scler
, vol.13
, pp. 372-377
-
-
Li, J.1
Paulson, J.M.2
Ye, F.D.3
Sung, M.4
Hollenberg, A.N.5
Rutkove, S.B.6
-
89
-
-
33846817493
-
Pyruvate slows disease progression in a G93A SOD1 mutant transgenic mouse model
-
COI: 1:CAS:528:DC%2BD2sXhsFOitbg%3D, PID: 17174029
-
Park J-H, Hong Y-H, Kim H-J, Kim S-M, Kim M-J, Park K-S, Sung J-J, Lee K-W (2007) Pyruvate slows disease progression in a G93A SOD1 mutant transgenic mouse model. Neurosci Lett 413:265–269
-
(2007)
Neurosci Lett
, vol.413
, pp. 265-269
-
-
Park, J.-H.1
Hong, Y.-H.2
Kim, H.-J.3
Kim, S.-M.4
Kim, M.-J.5
Park, K.-S.6
Sung, J.-J.7
Lee, K.-W.8
-
90
-
-
34548348971
-
Antioxidant strategies based on tomato-enriched food or pyruvate do not affect disease onset and survival in an animal model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD2sXpvFKhtbs%3D, PID: 17706944
-
Esposito E, Capasso M, di Tomasso N, Corona C, Pellegrini F, Uncini A, Vitaglione P, Fogliano V, Piantelli M, Sensi SL (2007) Antioxidant strategies based on tomato-enriched food or pyruvate do not affect disease onset and survival in an animal model of amyotrophic lateral sclerosis. Brain Res 1168:90–96
-
(2007)
Brain Res
, vol.1168
, pp. 90-96
-
-
Esposito, E.1
Capasso, M.2
di Tomasso, N.3
Corona, C.4
Pellegrini, F.5
Uncini, A.6
Vitaglione, P.7
Fogliano, V.8
Piantelli, M.9
Sensi, S.L.10
-
91
-
-
78649341669
-
Uridine ameliorates the pathological phenotype in transgenic G93A-ALS mice
-
COI: 1:CAS:528:DC%2BC3cXhsVekt7fE, PID: 20565334
-
Amante DJ, Kim J, Carreiro ST, Cooper AC, Jones SW, Li T, Moody JP, Edgerly CK, Bordiuk OL, Cormier K, Smith K, Ferrante RJ, Rusche J (2010) Uridine ameliorates the pathological phenotype in transgenic G93A-ALS mice. Amyotroph Lateral Scler 11:520–530
-
(2010)
Amyotroph Lateral Scler
, vol.11
, pp. 520-530
-
-
Amante, D.J.1
Kim, J.2
Carreiro, S.T.3
Cooper, A.C.4
Jones, S.W.5
Li, T.6
Moody, J.P.7
Edgerly, C.K.8
Bordiuk, O.L.9
Cormier, K.10
Smith, K.11
Ferrante, R.J.12
Rusche, J.13
-
92
-
-
0028933344
-
Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS)
-
COI: 1:CAS:528:DyaK2MXks1Khtrk%3D, PID: 7796176
-
Dal Canto MC, Gurney ME (1995) Neuropathological changes in two lines of mice carrying a transgene for mutant human Cu, Zn SOD, and in mice overexpressing wild type human SOD: a model of familial amyotrophic lateral sclerosis (FALS). Brain Res 676:25–40
-
(1995)
Brain Res
, vol.676
, pp. 25-40
-
-
Dal Canto, M.C.1
Gurney, M.E.2
-
93
-
-
0032079517
-
Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1
-
COI: 1:CAS:528:DyaK1cXivFChtLo%3D, PID: 9547233
-
Kong J, Xu Z (1998) Massive mitochondrial degeneration in motor neurons triggers the onset of amyotrophic lateral sclerosis in mice expressing a mutant SOD1. J Neurosci 18:3241–3250
-
(1998)
J Neurosci
, vol.18
, pp. 3241-3250
-
-
Kong, J.1
Xu, Z.2
-
94
-
-
0029053881
-
An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria
-
COI: 1:CAS:528:DyaK2MXms1Wrtr8%3D, PID: 7605627
-
Wong PC, Pardo CA, Borchelt DR, Lee MK, Copeland NG, Jenkins NA, Sisodia SS, Cleveland DW, Price DL (1995) An adverse property of a familial ALS-linked SOD1 mutation causes motor neuron disease characterized by vacuolar degeneration of mitochondria. Neuron 14:1105–1116
-
(1995)
Neuron
, vol.14
, pp. 1105-1116
-
-
Wong, P.C.1
Pardo, C.A.2
Borchelt, D.R.3
Lee, M.K.4
Copeland, N.G.5
Jenkins, N.A.6
Sisodia, S.S.7
Cleveland, D.W.8
Price, D.L.9
-
95
-
-
0035886428
-
Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity
-
COI: 1:CAS:528:DC%2BD3MXnslCitbo%3D, PID: 11676989
-
Bendotti C, Calvaresi N, Chiveri L, Prelle A, Moggio M, Braga M, Silani V, De Biasi S (2001) Early vacuolization and mitochondrial damage in motor neurons of FALS mice are not associated with apoptosis or with changes in cytochrome oxidase histochemical reactivity. J Neurol Sci 191:25–33
-
(2001)
J Neurol Sci
, vol.191
, pp. 25-33
-
-
Bendotti, C.1
Calvaresi, N.2
Chiveri, L.3
Prelle, A.4
Moggio, M.5
Braga, M.6
Silani, V.7
De Biasi, S.8
-
96
-
-
0036830072
-
Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD38Xos1Sjtb8%3D, PID: 12390515
-
Jung C, Higgins CMJ, Xu Z (2002) Mitochondrial electron transport chain complex dysfunction in a transgenic mouse model for amyotrophic lateral sclerosis. J Neurochem 83:535–545
-
(2002)
J Neurochem
, vol.83
, pp. 535-545
-
-
Jung, C.1
Higgins, C.M.J.2
Xu, Z.3
-
97
-
-
0037119407
-
Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice
-
COI: 1:CAS:528:DC%2BD38XmsVKitLc%3D, PID: 12050154
-
Mattiazzi M, D’Aurelio M, Gajewski CD, Martushova K, Kiaei M, Beal MF, Manfredi G (2002) Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice. J Biol Chem 277:29626–29633
-
(2002)
J Biol Chem
, vol.277
, pp. 29626-29633
-
-
Mattiazzi, M.1
D’Aurelio, M.2
Gajewski, C.D.3
Martushova, K.4
Kiaei, M.5
Beal, M.F.6
Manfredi, G.7
-
98
-
-
33645102302
-
Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice
-
COI: 1:CAS:528:DC%2BD28XivFSrurg%3D, PID: 16478527
-
Damiano M, Starkov AA, Petri S, Kipiani K, Kiaei M, Mattiazzi M, Flint Beal M, Manfredi G (2006) Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice. J Neurochem 96:1349–1361
-
(2006)
J Neurochem
, vol.96
, pp. 1349-1361
-
-
Damiano, M.1
Starkov, A.A.2
Petri, S.3
Kipiani, K.4
Kiaei, M.5
Mattiazzi, M.6
Flint Beal, M.7
Manfredi, G.8
-
99
-
-
0037088793
-
Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS
-
Higgins CMJ, Jung C, Ding H, Xu Z (2002) Mutant Cu, Zn superoxide dismutase that causes motoneuron degeneration is present in mitochondria in the CNS. J Neurosci 22:215
-
(2002)
J Neurosci
, vol.22
, pp. 215
-
-
Higgins, C.M.J.1
Jung, C.2
Ding, H.3
Xu, Z.4
-
100
-
-
33744816535
-
Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS
-
COI: 1:CAS:528:DC%2BD28Xls1aksr4%3D, PID: 16616851
-
Browne SE, Yang L, DiMauro J-P, Fuller SW, Licata SC, Beal MF (2006) Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS. Neurobiol Dis 22:599–610
-
(2006)
Neurobiol Dis
, vol.22
, pp. 599-610
-
-
Browne, S.E.1
Yang, L.2
DiMauro, J.-P.3
Fuller, S.W.4
Licata, S.C.5
Beal, M.F.6
-
101
-
-
84857790779
-
Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice
-
COI: 1:CAS:528:DC%2BC38Xjt1Wqtrg%3D, PID: 22068226
-
Miyazaki K, Masamoto K, Morimoto N, Kurata T, Mimoto T, Obata T, Kanno I, Abe K (2012) Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice. J Cereb Blood Flow Metab 32:456–467
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, pp. 456-467
-
-
Miyazaki, K.1
Masamoto, K.2
Morimoto, N.3
Kurata, T.4
Mimoto, T.5
Obata, T.6
Kanno, I.7
Abe, K.8
-
102
-
-
0345426778
-
Up-regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD3sXovFOhsLs%3D, PID: 14500553
-
Dupuis L, di Scala F, Rene F, de Tapia M, Oudart H, Pradat P-F, Meininger V, Loeffler J-P (2003) Up-regulation of mitochondrial uncoupling protein 3 reveals an early muscular metabolic defect in amyotrophic lateral sclerosis. FASEB J 17:2091–2093
-
(2003)
FASEB J
, vol.17
, pp. 2091-2093
-
-
Dupuis, L.1
di Scala, F.2
Rene, F.3
de Tapia, M.4
Oudart, H.5
Pradat, P.-F.6
Meininger, V.7
Loeffler, J.-P.8
-
103
-
-
0034811135
-
Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibers isolated from G93AhumanSOD1 transgenic mice
-
COI: 1:STN:280:DC%2BD3MrkvFejsw%3D%3D, PID: 11595514
-
Leclerc N, Ribera F, Zoll J, Warter JM, Poindron P, Lampert E, Borg J (2001) Selective changes in mitochondria respiratory properties in oxidative or glycolytic muscle fibers isolated from G93AhumanSOD1 transgenic mice. Neuromuscul disord 11:722–727
-
(2001)
Neuromuscul disord
, vol.11
, pp. 722-727
-
-
Leclerc, N.1
Ribera, F.2
Zoll, J.3
Warter, J.M.4
Poindron, P.5
Lampert, E.6
Borg, J.7
-
104
-
-
34548145662
-
Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BD2sXnsFWht74%3D, PID: 17438338
-
Fergani A, Oudart H, Gonzalez De Aguilar J-L, Fricker B, Rene F, Hocquette J-F, Meininger V, Dupuis L, Loeffler J-P (2007) Increased peripheral lipid clearance in an animal model of amyotrophic lateral sclerosis. J Lipid Res 48:1571–1580
-
(2007)
J Lipid Res
, vol.48
, pp. 1571-1580
-
-
Fergani, A.1
Oudart, H.2
Gonzalez De Aguilar, J.-L.3
Fricker, B.4
Rene, F.5
Hocquette, J.-F.6
Meininger, V.7
Dupuis, L.8
Loeffler, J.-P.9
-
105
-
-
84878995994
-
Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury
-
COI: 1:CAS:528:DC%2BC3sXhtVejtrjM, PID: 23785402
-
Hussain G, Schmitt F, Henriques A, Lequeu T, Rene F, Bindler F, Dirrig-Grosch S, Oudart H, Palamiuc L, Metz-Boutigue M-H, Dupuis L, Marchioni E, Gonzalez De Aguilar J-L, Loeffler J-P (2013) Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury. PLoS One 8:e64525
-
(2013)
PLoS One
, vol.8
, pp. e64525
-
-
Hussain, G.1
Schmitt, F.2
Henriques, A.3
Lequeu, T.4
Rene, F.5
Bindler, F.6
Dirrig-Grosch, S.7
Oudart, H.8
Palamiuc, L.9
Metz-Boutigue, M.-H.10
Dupuis, L.11
Marchioni, E.12
Gonzalez De Aguilar, J.-L.13
Loeffler, J.-P.14
-
106
-
-
77958012134
-
Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism
-
COI: 1:CAS:528:DC%2BC3cXhtF2gtrnK, PID: 20660762
-
Chiang P-M, Ling J, Jeong YH, Price DL, Aja SM, Wong PC (2010) Deletion of TDP-43 down-regulates Tbc1d1, a gene linked to obesity, and alters body fat metabolism. Proc Natl Acad Sci USA 107:16320–16324
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16320-16324
-
-
Chiang, P.-M.1
Ling, J.2
Jeong, Y.H.3
Price, D.L.4
Aja, S.M.5
Wong, P.C.6
-
107
-
-
84881533452
-
TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis
-
COI: 1:CAS:528:DC%2BC3sXhtlaqsb7L, PID: 23967244
-
Stallings NR, Puttaparthi K, Dowling KJ, Luther CM, Burns DK, Davis K, Elliott JL (2013) TDP-43, an ALS linked protein, regulates fat deposition and glucose homeostasis. PLoS One 8:e71793
-
(2013)
PLoS One
, vol.8
, pp. e71793
-
-
Stallings, N.R.1
Puttaparthi, K.2
Dowling, K.J.3
Luther, C.M.4
Burns, D.K.5
Davis, K.6
Elliott, J.L.7
-
108
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
COI: 1:CAS:528:DC%2BC3cXhtF2gt7zE, PID: 20736350
-
Shan X, Chiang P-M, Price DL, Wong PC (2010) Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc Natl Acad Sci USA 107:16325–16330
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.-M.2
Price, D.L.3
Wong, P.C.4
-
109
-
-
84887540422
-
The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons
-
COI: 1:CAS:528:DC%2BC3sXhslCrsrvL, PID: 23827948
-
Wang W, Li L, Lin W-L, Dickson DW, Petrucelli L, Zhang T, Wang X (2013) The ALS disease-associated mutant TDP-43 impairs mitochondrial dynamics and function in motor neurons. Hum Mol Genet 22:4706–4719
-
(2013)
Hum Mol Genet
, vol.22
, pp. 4706-4719
-
-
Wang, W.1
Li, L.2
Lin, W.-L.3
Dickson, D.W.4
Petrucelli, L.5
Zhang, T.6
Wang, X.7
-
110
-
-
77956199371
-
Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice
-
COI: 1:CAS:528:DC%2BC3cXhtVOhsbrF, PID: 20702714
-
Xu Y-F, Gendron TF, Zhang Y-J, Lin W-L, D’Alton S, Sheng H, Casey MC, Tong J, Knight J, Yu X, Rademakers R, Boylan K, Hutton M, McGowan E, Dickson DW, Lewis J, Petrucelli L (2010) Wild-type human TDP-43 expression causes TDP-43 phosphorylation, mitochondrial aggregation, motor deficits, and early mortality in transgenic mice. J Neurosci 30:10851–10859
-
(2010)
J Neurosci
, vol.30
, pp. 10851-10859
-
-
Xu, Y.-F.1
Gendron, T.F.2
Zhang, Y.-J.3
Lin, W.-L.4
D’Alton, S.5
Sheng, H.6
Casey, M.C.7
Tong, J.8
Knight, J.9
Yu, X.10
Rademakers, R.11
Boylan, K.12
Hutton, M.13
McGowan, E.14
Dickson, D.W.15
Lewis, J.16
Petrucelli, L.17
-
111
-
-
78449287318
-
Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions
-
COI: 1:CAS:528:DC%2BC3cXhsVKqtL%2FI
-
Huang EJ, Zhang J, Geser F, Trojanowski JQ, Strober JB, Dickson DW, Brown RH Jr, Shapiro BE, Lomen-Hoerth C (2010) Extensive FUS-immunoreactive pathology in juvenile amyotrophic lateral sclerosis with basophilic inclusions. Brain Pathol (Zurich, Switzerland) 20:1069–1076
-
(2010)
Brain Pathol (Zurich, Switzerland)
, vol.20
, pp. 1069-1076
-
-
Huang, E.J.1
Zhang, J.2
Geser, F.3
Trojanowski, J.Q.4
Strober, J.B.5
Dickson, D.W.6
Brown, R.H.7
Shapiro, B.E.8
Lomen-Hoerth, C.9
-
112
-
-
84867289496
-
Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats
-
COI: 1:CAS:528:DC%2BC38XhsFCgsLjO, PID: 22833456
-
Huang C, Tong J, Bi F, Wu Q, Huang B, Zhou H, Xia X-G (2012) Entorhinal cortical neurons are the primary targets of FUS mislocalization and ubiquitin aggregation in FUS transgenic rats. Hum Mol Genet 21:4602–4614
-
(2012)
Hum Mol Genet
, vol.21
, pp. 4602-4614
-
-
Huang, C.1
Tong, J.2
Bi, F.3
Wu, Q.4
Huang, B.5
Zhou, H.6
Xia, X.-G.7
-
113
-
-
84897101638
-
Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models
-
PID: 24595038
-
Perera ND, Sheean RK, Scott JW, Kemp BE, Horne MK, Turner BJ (2014) Mutant TDP-43 deregulates AMPK activation by PP2A in ALS models. PLoS One 9:e90449
-
(2014)
PLoS One
, vol.9
, pp. e90449
-
-
Perera, N.D.1
Sheean, R.K.2
Scott, J.W.3
Kemp, B.E.4
Horne, M.K.5
Turner, B.J.6
-
114
-
-
84908647710
-
Adenosine monophosphate-activated protein kinase activation enhances embryonic neural stem cell apoptosis in a mouse model of amyotrophic lateral sclerosis
-
PID: 25422638
-
Sui Y, Zhao Z, Liu R, Cai B, Fan D (2014) Adenosine monophosphate-activated protein kinase activation enhances embryonic neural stem cell apoptosis in a mouse model of amyotrophic lateral sclerosis. Neural Regen Res 9:1770–1778
-
(2014)
Neural Regen Res
, vol.9
, pp. 1770-1778
-
-
Sui, Y.1
Zhao, Z.2
Liu, R.3
Cai, B.4
Fan, D.5
-
115
-
-
84964266916
-
Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC2MXntVelsQ%3D%3D, PID: 25592834
-
Liu Y-J, Lee L-M, Lai H-L, Chern Y (2015) Aberrant activation of AMP-activated protein kinase contributes to the abnormal distribution of HuR in amyotrophic lateral sclerosis. FEBS Lett 589:432–439
-
(2015)
FEBS Lett
, vol.589
, pp. 432-439
-
-
Liu, Y.-J.1
Lee, L.-M.2
Lai, H.-L.3
Chern, Y.4
-
116
-
-
84922429320
-
Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis
-
COI: 1:CAS:528:DC%2BC2MXhsVOhsLzN, PID: 25256353
-
Liu YJ, Ju TC, Chen HM, Jang YS, Lee LM, Lai HL, Tai HC, Fang JM, Lin YL, Tu PH, Chern Y (2015) Activation of AMP-activated protein kinase α1 mediates mislocalization of TDP-43 in amyotrophic lateral sclerosis. Hum Mol Genet 24:787–801
-
(2015)
Hum Mol Genet
, vol.24
, pp. 787-801
-
-
Liu, Y.J.1
Ju, T.C.2
Chen, H.M.3
Jang, Y.S.4
Lee, L.M.5
Lai, H.L.6
Tai, H.C.7
Fang, J.M.8
Lin, Y.L.9
Tu, P.H.10
Chern, Y.11
-
117
-
-
84899134148
-
Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice
-
COI: 1:CAS:528:DC%2BC2cXntFOlt74%3D
-
Mancuso R, del Valle J, Modol L, Martinez A, Granado-Serrano AB, Ramirez-Nunez O, Pallas M, Portero-Otin M, Osta R, Navarro X (2014) Resveratrol improves motoneuron function and extends survival in SOD1(G93A) ALS mice. Neurother 11:419–432
-
(2014)
Neurother
, vol.11
, pp. 419-432
-
-
Mancuso, R.1
del Valle, J.2
Modol, L.3
Martinez, A.4
Granado-Serrano, A.B.5
Ramirez-Nunez, O.6
Pallas, M.7
Portero-Otin, M.8
Osta, R.9
Navarro, X.10
|