-
1
-
-
0029805172
-
Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly
-
Beckman J.S., and Koppenol W.H. Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly. Am. J. Physiol. 40 (1996) C1424-C1437
-
(1996)
Am. J. Physiol.
, vol.40
-
-
Beckman, J.S.1
Koppenol, W.H.2
-
2
-
-
0034961104
-
Amyotrophic lateral sclerosis: pathogenesis
-
Brown R.H., and Robberecht W. Amyotrophic lateral sclerosis: pathogenesis. Semin. Neurol. 21 (2001) 131-139
-
(2001)
Semin. Neurol.
, vol.21
, pp. 131-139
-
-
Brown, R.H.1
Robberecht, W.2
-
3
-
-
0036144231
-
Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis
-
Cassina P., Peluffo H., Pehar M., Martinez-Palma L., Ressia A., Beckman J.S., Estevez A.G., and Barbeito L. Peroxynitrite triggers a phenotypic transformation in spinal cord astrocytes that induces motor neuron apoptosis. J. Neurosci. Res. 67 (2002) 21-29
-
(2002)
J. Neurosci. Res.
, vol.67
, pp. 21-29
-
-
Cassina, P.1
Peluffo, H.2
Pehar, M.3
Martinez-Palma, L.4
Ressia, A.5
Beckman, J.S.6
Estevez, A.G.7
Barbeito, L.8
-
4
-
-
0035516124
-
From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS
-
Cleveland D.W., and Rothstein J.D. From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS. Nat. Rev. Neurosci. 2 (2001) 806-819
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 806-819
-
-
Cleveland, D.W.1
Rothstein, J.D.2
-
5
-
-
0032568546
-
Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants
-
Corson L.B., Strain J.J., Culotta V.C., and Cleveland D.W. Chaperone-facilitated copper binding is a property common to several classes of familial amyotrophic lateral sclerosis-linked superoxide dismutase mutants. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 6361-6366
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 6361-6366
-
-
Corson, L.B.1
Strain, J.J.2
Culotta, V.C.3
Cleveland, D.W.4
-
6
-
-
0030703154
-
Pyruvate protects neurons against hydrogen peroxide-induced toxicity
-
Desagher S., Glowinski J., and Prémont J. Pyruvate protects neurons against hydrogen peroxide-induced toxicity. J. Neurosci. 17 (1997) 9060-9067
-
(1997)
J. Neurosci.
, vol.17
, pp. 9060-9067
-
-
Desagher, S.1
Glowinski, J.2
Prémont, J.3
-
7
-
-
0036895241
-
Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS
-
Drachman D.B., Frank K., Dykes-Hoberg M., Teismann P., Almer G., Przedborski S., and Rothstein J.D. Cyclooxygenase 2 inhibition protects motor neurons and prolongs survival in a transgenic mouse model of ALS. Ann. Neurol. 52 (2002) 771-778
-
(2002)
Ann. Neurol.
, vol.52
, pp. 771-778
-
-
Drachman, D.B.1
Frank, K.2
Dykes-Hoberg, M.3
Teismann, P.4
Almer, G.5
Przedborski, S.6
Rothstein, J.D.7
-
8
-
-
21844454460
-
Mitochondria in amyotrophic lateral sclerosis: a trigger and a target
-
Dupuis L., Gonzalez de Aguilar J.L., Oudart H., de Tapia M., Barbeito L., and Loeffler J.P. Mitochondria in amyotrophic lateral sclerosis: a trigger and a target. Neurodegener Dis. 1 (2004) 245-254
-
(2004)
Neurodegener Dis.
, vol.1
, pp. 245-254
-
-
Dupuis, L.1
Gonzalez de Aguilar, J.L.2
Oudart, H.3
de Tapia, M.4
Barbeito, L.5
Loeffler, J.P.6
-
9
-
-
3343020674
-
Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model
-
Dupuis L., Oudart H., Rene F., Gonzalez de Aguilar J.L., and Loeffler J.P. Evidence for defective energy homeostasis in amyotrophic lateral sclerosis: benefit of a high-energy diet in a transgenic mouse model. Proc. Natl. Acad. Sci. U.S.A. 101 (2004) 11159-11164
-
(2004)
Proc. Natl. Acad. Sci. U.S.A.
, vol.101
, pp. 11159-11164
-
-
Dupuis, L.1
Oudart, H.2
Rene, F.3
Gonzalez de Aguilar, J.L.4
Loeffler, J.P.5
-
10
-
-
33645037573
-
Early abnormalities in transgenic mouse models of amyotrophic lateral sclerosis
-
Durand J., Amendola J., Bories C., and d'Incamps B.L. Early abnormalities in transgenic mouse models of amyotrophic lateral sclerosis. J. Physiol. 99 (2006) 211-220
-
(2006)
J. Physiol.
, vol.99
, pp. 211-220
-
-
Durand, J.1
Amendola, J.2
Bories, C.3
d'Incamps, B.L.4
-
11
-
-
0028294023
-
Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle
-
Garcia C.K., Goldstein J.L., Pathak R.K., Anderson R.G., and Brown M.S. Molecular characterization of a membrane transporter for lactate, pyruvate, and other monocarboxylates: implications for the Cori cycle. Cell 76 (1994) 865-873
-
(1994)
Cell
, vol.76
, pp. 865-873
-
-
Garcia, C.K.1
Goldstein, J.L.2
Pathak, R.K.3
Anderson, R.G.4
Brown, M.S.5
-
12
-
-
0030953738
-
The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide
-
Giandomenico A.R., Cerniglia G.E., Biaglow J.E., Stevens C.W., and Koch C.J. The importance of sodium pyruvate in assessing damage produced by hydrogen peroxide. Free Radic. Biol. Med. 23 (1997) 426-434
-
(1997)
Free Radic. Biol. Med.
, vol.23
, pp. 426-434
-
-
Giandomenico, A.R.1
Cerniglia, G.E.2
Biaglow, J.E.3
Stevens, C.W.4
Koch, C.J.5
-
13
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney M.E., Pu H., Chiu A.Y., Dal Canto M.C., Polchow C.Y., Alexander D.D., Caliendo J., Hentati A., Kwon Y.W., and Deng H.X. Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264 (1994) 1772-1775
-
(1994)
Science
, vol.264
, pp. 1772-1775
-
-
Gurney, M.E.1
Pu, H.2
Chiu, A.Y.3
Dal Canto, M.C.4
Polchow, C.Y.5
Alexander, D.D.6
Caliendo, J.7
Hentati, A.8
Kwon, Y.W.9
Deng, H.X.10
-
14
-
-
0035936804
-
Amyotrophic lateral sclerosis: unfolding the toxicity of the misfolded
-
Julien J.P. Amyotrophic lateral sclerosis: unfolding the toxicity of the misfolded. Cell 104 (2001) 581-591
-
(2001)
Cell
, vol.104
, pp. 581-591
-
-
Julien, J.P.1
-
15
-
-
17844375077
-
Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity
-
Kim H.J., Kim J.M., Park J.H., Sung J.J., Kim M., and Lee K.W. Pyruvate protects motor neurons expressing mutant superoxide dismutase 1 against copper toxicity. Neuroreport 16 (2005) 585-589
-
(2005)
Neuroreport
, vol.16
, pp. 585-589
-
-
Kim, H.J.1
Kim, J.M.2
Park, J.H.3
Sung, J.J.4
Kim, M.5
Lee, K.W.6
-
16
-
-
0035888871
-
Protection by pyruvate against transient forebrain ischemia in rats
-
Lee J.Y., Kim Y.H., and Koh J.Y. Protection by pyruvate against transient forebrain ischemia in rats. J. Neurosci. 21 (2001) RC171
-
(2001)
J. Neurosci.
, vol.21
-
-
Lee, J.Y.1
Kim, Y.H.2
Koh, J.Y.3
-
17
-
-
0032764587
-
The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids
-
Liu D., Wen J., Liu J., and Li L. The roles of free radicals in amyotrophic lateral sclerosis: reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids. FASEB J. 13 (1999) 2318-2328
-
(1999)
FASEB J.
, vol.13
, pp. 2318-2328
-
-
Liu, D.1
Wen, J.2
Liu, J.3
Li, L.4
-
18
-
-
21544445251
-
Metabolic cardioprotection by pyruvate: recent progress
-
Mallet R.T., Sun J., Knott E.M., Sharma A.B., and Olivencia-Yurvati A.H. Metabolic cardioprotection by pyruvate: recent progress. Exp. Biol. Med. 230 (2005) 435-443
-
(2005)
Exp. Biol. Med.
, vol.230
, pp. 435-443
-
-
Mallet, R.T.1
Sun, J.2
Knott, E.M.3
Sharma, A.B.4
Olivencia-Yurvati, A.H.5
-
19
-
-
0032850167
-
Pyruvate and lactate protect striatal neurons against N-methyl-d-aspartate-induced neurotoxicity
-
Maus M., Marin P., Israel M., Glowinski J., and Prémont J. Pyruvate and lactate protect striatal neurons against N-methyl-d-aspartate-induced neurotoxicity. Eur. J. Neurosci. 11 (1999) 3215-3224
-
(1999)
Eur. J. Neurosci.
, vol.11
, pp. 3215-3224
-
-
Maus, M.1
Marin, P.2
Israel, M.3
Glowinski, J.4
Prémont, J.5
-
20
-
-
0037403558
-
Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells
-
Mazzio E.A., and Soliman K.F. Cytoprotection of pyruvic acid and reduced beta-nicotinamide adenine dinucleotide against hydrogen peroxide toxicity in neuroblastoma cells. Neurochem. Res. 28 (2003) 733-741
-
(2003)
Neurochem. Res.
, vol.28
, pp. 733-741
-
-
Mazzio, E.A.1
Soliman, K.F.2
-
21
-
-
0027401203
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen D.R., Siddique T., Patterson D., Figlewicz D.A., Sapp P., Hentati A., Donaldson D., Goto J., O'Regan J.P., and Deng H.X. Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 362 (1993) 59-62
-
(1993)
Nature
, vol.362
, pp. 59-62
-
-
Rosen, D.R.1
Siddique, T.2
Patterson, D.3
Figlewicz, D.A.4
Sapp, P.5
Hentati, A.6
Donaldson, D.7
Goto, J.8
O'Regan, J.P.9
Deng, H.X.10
-
22
-
-
0035978743
-
Amyotrophic lateral sclerosis
-
Rowland L.P., and Shneider N.A. Amyotrophic lateral sclerosis. NEJM 344 (2001) 1688-1700
-
(2001)
NEJM
, vol.344
, pp. 1688-1700
-
-
Rowland, L.P.1
Shneider, N.A.2
-
23
-
-
0141560478
-
Neuroprotective effects of pyruvate in the quinolinic acid rat model of Huntington's disease
-
Ryu J.K., Kim S.U., and McLarnon J.G. Neuroprotective effects of pyruvate in the quinolinic acid rat model of Huntington's disease. Exp. Neurol. 183 (2003) 700-704
-
(2003)
Exp. Neurol.
, vol.183
, pp. 700-704
-
-
Ryu, J.K.1
Kim, S.U.2
McLarnon, J.G.3
-
24
-
-
0034659123
-
Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1
-
Said Ahmed M., Hung W.Y., Zu J.S., Hockberger P., and Siddique T. Increased reactive oxygen species in familial amyotrophic lateral sclerosis with mutations in SOD1. J. Neurol. Sci. 176 (2000) 88-94
-
(2000)
J. Neurol. Sci.
, vol.176
, pp. 88-94
-
-
Said Ahmed, M.1
Hung, W.Y.2
Zu, J.S.3
Hockberger, P.4
Siddique, T.5
-
25
-
-
23944490153
-
The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice
-
Schutz B., Reimann J., Dumitrescu-Ozimek L., Kappes-Horn K., Landreth G.E., Schurmann B., Zimmer A., and Heneka M.T. The oral antidiabetic pioglitazone protects from neurodegeneration and amyotrophic lateral sclerosis-like symptoms in superoxide dismutase-G93A transgenic mice. J. Neurosci. 25 (2005) 7805-7812
-
(2005)
J. Neurosci.
, vol.25
, pp. 7805-7812
-
-
Schutz, B.1
Reimann, J.2
Dumitrescu-Ozimek, L.3
Kappes-Horn, K.4
Landreth, G.E.5
Schurmann, B.6
Zimmer, A.7
Heneka, M.T.8
-
26
-
-
0034194361
-
Zinc-induced corticalneuronal death: contribution of energy failure attributable to loss of NAD+ and inhibition of glycolysis
-
Sheline C.T., Behrens M.M., and Choi D.W. Zinc-induced corticalneuronal death: contribution of energy failure attributable to loss of NAD+ and inhibition of glycolysis. J. Neurosci. 20 (2000) 3139-3146
-
(2000)
J. Neurosci.
, vol.20
, pp. 3139-3146
-
-
Sheline, C.T.1
Behrens, M.M.2
Choi, D.W.3
-
27
-
-
0038693216
-
The basic aspects of therapeutics in amyotrophic lateral sclerosis
-
Strong M.J. The basic aspects of therapeutics in amyotrophic lateral sclerosis. Pharmacol. Ther. 98 (2003) 379-414
-
(2003)
Pharmacol. Ther.
, vol.98
, pp. 379-414
-
-
Strong, M.J.1
-
28
-
-
0029927343
-
Metabolic coupling between glia and neurons
-
Tsacopoulos M., and Magistretti P.J. Metabolic coupling between glia and neurons. J. Neurosci. 16 (1996) 877-885
-
(1996)
J. Neurosci.
, vol.16
, pp. 877-885
-
-
Tsacopoulos, M.1
Magistretti, P.J.2
-
29
-
-
0035873398
-
Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity
-
Wang X.F., and Cynader M.S. Pyruvate released by astrocytes protects neurons from copper-catalyzed cysteine neurotoxicity. J. Neurosci. 21 (2001) 3322-3331
-
(2001)
J. Neurosci.
, vol.21
, pp. 3322-3331
-
-
Wang, X.F.1
Cynader, M.S.2
-
30
-
-
0038235339
-
Assessing disease onset and progression in the SOD1 mouse model of ALS
-
Weydt P., Hong S.Y., Kliot M., and Möller T. Assessing disease onset and progression in the SOD1 mouse model of ALS. Neuroreport 14 (2003) 1051-1054
-
(2003)
Neuroreport
, vol.14
, pp. 1051-1054
-
-
Weydt, P.1
Hong, S.Y.2
Kliot, M.3
Möller, T.4
-
31
-
-
0029671220
-
Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis
-
Wiedau-Pazos M., Goto J.J., Rabizadeh S., Gralla E.B., Roe J.A., Lee M.K., Valentine J.S., and Bredesen D.E. Altered reactivity of superoxide dismutase in familial amyotrophic lateral sclerosis. Science 271 (1996) 515-518
-
(1996)
Science
, vol.271
, pp. 515-518
-
-
Wiedau-Pazos, M.1
Goto, J.J.2
Rabizadeh, S.3
Gralla, E.B.4
Roe, J.A.5
Lee, M.K.6
Valentine, J.S.7
Bredesen, D.E.8
|