-
1
-
-
0027164824
-
Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis
-
Rosen DR (1993) Mutations in Cu/Zn superoxide dismutase gene are associated with familial amyotrophic lateral sclerosis. Nature 364(6435):362.
-
(1993)
Nature
, vol.364
, Issue.6435
, pp. 362
-
-
Rosen, D.R.1
-
2
-
-
0028284779
-
Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation
-
Gurney ME, et al. (1994) Motor neuron degeneration in mice that express a human Cu,Zn superoxide dismutase mutation. Science 264(5166):1772-1775.
-
(1994)
Science
, vol.264
, Issue.5166
, pp. 1772-1775
-
-
Gurney, M.E.1
-
3
-
-
3943102116
-
Unraveling the mechanisms involved in motor neuron degeneration in ALS
-
Bruijn LI, Miller TM, Cleveland DW (2004) Unraveling the mechanisms involved in motor neuron degeneration in ALS. Annu Rev Neurosci 27:723-749.
-
(2004)
Annu Rev Neurosci
, vol.27
, pp. 723-749
-
-
Bruijn, L.I.1
Miller, T.M.2
Cleveland, D.W.3
-
4
-
-
84871497430
-
Multimodal actions of neural stem cells in a mouse model of ALS: A meta-analysis
-
Teng YD, et al. (2012) Multimodal actions of neural stem cells in a mouse model of ALS: A meta-analysis. Science Transl Med 4(165):165ra164.
-
(2012)
Science Transl Med
, vol.4
, Issue.165
-
-
Teng, Y.D.1
-
5
-
-
0028933324
-
Protection against CNS ischemia by temporary interruption of function-related processes of neurons
-
Ames A, 3rd, Maynard KI, Kaplan S (1995) Protection against CNS ischemia by temporary interruption of function-related processes of neurons. J Cereb Blood Flow Metab 15(3): 433-439.
-
(1995)
J Cereb Blood Flow Metab
, vol.15
, Issue.3
, pp. 433-439
-
-
Ames Iii, A.1
Maynard, K.I.2
Kaplan, S.3
-
6
-
-
49349115297
-
Amiloride is neuroprotective in an MPTP model of Parkinson's disease
-
Arias RL, et al. (2008) Amiloride is neuroprotective in an MPTP model of Parkinson's disease. Neurobiol Dis 31(3):334-341.
-
(2008)
Neurobiol Dis
, vol.31
, Issue.3
, pp. 334-341
-
-
Arias, R.L.1
-
7
-
-
36849009834
-
Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system
-
Friese MA, et al. (2007) Acid-sensing ion channel-1 contributes to axonal degeneration in autoimmune inflammation of the central nervous system. Nat Med 13(12):1483-1489.
-
(2007)
Nat Med
, vol.13
, Issue.12
, pp. 1483-1489
-
-
Friese, M.A.1
-
8
-
-
0028906351
-
Acidosis causes failure of astrocyte glutamate uptake during hypoxia
-
Swanson RA, Farrell K, Simon RP (1995) Acidosis causes failure of astrocyte glutamate uptake during hypoxia. J Cereb Blood Flow Metab 15(3):417-424.
-
(1995)
J Cereb Blood Flow Metab
, vol.15
, Issue.3
, pp. 417-424
-
-
Swanson, R.A.1
Farrell, K.2
Simon, R.P.3
-
9
-
-
0024373791
-
Influence of in vitro lactic acidosis on central nervous system neurons
-
Khan NA, Guevara P, Sotelo J (1989) Influence of in vitro lactic acidosis on central nervous system neurons. Pathol Biol (Paris) 37(6):725-729.
-
(1989)
Pathol Biol (Paris)
, vol.37
, Issue.6
, pp. 725-729
-
-
Khan, N.A.1
Guevara, P.2
Sotelo, J.3
-
10
-
-
0034307612
-
Potentiation of a voltage-gated proton current in acidosis-induced swelling of rat microglia
-
Morihata H, Nakamura F, Tsutada T, Kuno M (2000) Potentiation of a voltage-gated proton current in acidosis-induced swelling of rat microglia. J Neurosci 20(19):7220-7227.
-
(2000)
J Neurosci
, vol.20
, Issue.19
, pp. 7220-7227
-
-
Morihata, H.1
Nakamura, F.2
Tsutada, T.3
Kuno, M.4
-
11
-
-
14644412870
-
Acidosis causes endoplasmic reticulum stress and caspase- 12-mediated astrocyte death
-
Aoyama K, et al. (2005) Acidosis causes endoplasmic reticulum stress and caspase- 12-mediated astrocyte death. J Cereb Blood Flow Metab 25(3):358-370.
-
(2005)
J Cereb Blood Flow Metab
, vol.25
, Issue.3
, pp. 358-370
-
-
Aoyama, K.1
-
12
-
-
0027435233
-
Relations between intracellular ions and energy metabolism under acidotic conditions: A study with nigericin in synaptosomes, neurons, and C6 glioma cells
-
Ereci-nska M, Nelson D, Dagani F, Deas J, Silver IA (1993) Relations between intracellular ions and energy metabolism under acidotic conditions: A study with nigericin in synaptosomes, neurons, and C6 glioma cells. J Neurochem 61(4):1356-1368.
-
(1993)
J Neurochem
, vol.61
, Issue.4
, pp. 1356-1368
-
-
Erecinska, M.1
Nelson, D.2
Dagani, F.3
Deas, J.4
Silver, I.A.5
-
13
-
-
79551690481
-
Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis
-
Kirby J, et al. (2011) Phosphatase and tensin homologue/protein kinase B pathway linked to motor neuron survival in human superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain 134(Pt 2):506-517.
-
(2011)
Brain
, vol.134
, Issue.PART 2
, pp. 506-517
-
-
Kirby, J.1
-
14
-
-
84874950486
-
Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration
-
Behan AT, et al. (2013) Acidotoxicity and acid-sensing ion channels contribute to motoneuron degeneration. Cell Death Differ 20(4):589-598.
-
(2013)
Cell Death Differ
, vol.20
, Issue.4
, pp. 589-598
-
-
Behan, A.T.1
-
15
-
-
33745728330
-
Strong ion difference and strong anion gap: The Stewart approach to acid base disturbances
-
Rinaldi S, De Gaudio AR (2005) Strong ion difference and strong anion gap: The Stewart approach to acid base disturbances. Curr Anaesth Crit Care 16(6):395-402.
-
(2005)
Curr Anaesth Crit Care
, vol.16
, Issue.6
, pp. 395-402
-
-
Rinaldi, S.1
De Gaudio, A.R.2
-
16
-
-
2342418280
-
Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury
-
Kaplan LJ, Kellum JA (2004) Initial pH, base deficit, lactate, anion gap, strong ion difference, and strong ion gap predict outcome from major vascular injury. Crit Care Med 32(5):1120-1124.
-
(2004)
Crit Care Med
, vol.32
, Issue.5
, pp. 1120-1124
-
-
Kaplan, L.J.1
Kellum, J.A.2
-
17
-
-
78449276686
-
Fluids, pH, ions and electrolytes
-
Kaplan LJ, Kellum JA (2010) Fluids, pH, ions and electrolytes. Curr Opin Crit Care 16(4): 323-331.
-
(2010)
Curr Opin Crit Care
, vol.16
, Issue.4
, pp. 323-331
-
-
Kaplan, L.J.1
Kellum, J.A.2
-
18
-
-
0020960982
-
Biochemistry and differential diagnosis of metabolic acidoses
-
Sestoft L, Bartels PD (1983) Biochemistry and differential diagnosis of metabolic acidoses. Clin Endocrinol Metab 12(2):287-302.
-
(1983)
Clin Endocrinol Metab
, vol.12
, Issue.2
, pp. 287-302
-
-
Sestoft, L.1
Bartels, P.D.2
-
19
-
-
80052928827
-
Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis
-
Ferraiuolo L, et al. (2011) Dysregulation of astrocyte-motoneuron cross-talk in mutant superoxide dismutase 1-related amyotrophic lateral sclerosis. Brain 134(Pt 9):2627-2641.
-
(2011)
Brain
, vol.134
, Issue.PART 9
, pp. 2627-2641
-
-
Ferraiuolo, L.1
-
20
-
-
0023675947
-
Effects of acetazolamide on cerebral acid-base balance
-
Bickler PE, Litt L, Banville DL, Severinghaus JW (1988) Effects of acetazolamide on cerebral acid-base balance. J Appl Physiol 65(1):422-427.
-
(1988)
J Appl Physiol
, vol.65
, Issue.1
, pp. 422-427
-
-
Bickler, P.E.1
Litt, L.2
Banville, D.L.3
Severinghaus, J.W.4
-
21
-
-
0016769857
-
Brain carbonic acid acidosis after acetazolamide
-
Heuser D, Astrup J, Lassen NA, Betz BE (1975) Brain carbonic acid acidosis after acetazolamide. Acta Physiol Scand 93(3):385-390.
-
(1975)
Acta Physiol Scand
, vol.93
, Issue.3
, pp. 385-390
-
-
Heuser, D.1
Astrup, J.2
Lassen, N.A.3
Betz, B.E.4
-
22
-
-
0000995321
-
Glycogen storage disease type II: Acid alpha-glucosidase (acid maltase) deficiency
-
eds Scriver CA, Beaudet AL, Valle D, Sly WS McGraw-Hill, New York), 8th Ed
-
Hirshhorn R, Reuser AJJ (2001) Glycogen storage disease type II: Acid alpha-glucosidase (acid maltase) deficiency. The Metabolic and Molecular Bases of Inherited Disease, eds Scriver CA, Beaudet AL, Valle D, Sly WS (McGraw-Hill, New York), 8th Ed, pp 3389-3420.
-
(2001)
The Metabolic and Molecular Bases of Inherited Disease
, pp. 3389-3420
-
-
Hirshhorn, R.1
Ajj, R.2
-
23
-
-
52249123294
-
Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice
-
Sidman RL, et al. (2008) Temporal neuropathologic and behavioral phenotype of 6neo/6neo Pompe disease mice. J Neuropathol Exp Neurol 67(8):803-818.
-
(2008)
J Neuropathol Exp Neurol
, vol.67
, Issue.8
, pp. 803-818
-
-
Sidman, R.L.1
-
24
-
-
0032714568
-
Importance of glycosidases in mammalian glycoprotein biosynthesis
-
Herscovics A (1999) Importance of glycosidases in mammalian glycoprotein biosynthesis. Biochim Biophys Acta 1473(1):96-107.
-
(1999)
Biochim Biophys Acta
, vol.1473
, Issue.1
, pp. 96-107
-
-
Herscovics, A.1
-
25
-
-
80052783545
-
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
-
Haidet-Phillips AM, et al. (2011) Astrocytes from familial and sporadic ALS patients are toxic to motor neurons. Nat Biotechnol 29(9):824-828.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.9
, pp. 824-828
-
-
Haidet-Phillips, A.M.1
-
26
-
-
0029661207
-
A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data
-
Tandan R, et al. (1996) A controlled trial of amino acid therapy in amyotrophic lateral sclerosis: I. Clinical, functional, and maximum isometric torque data. Neurology 47(5): 1220-1226.
-
(1996)
Neurology
, vol.47
, Issue.5
, pp. 1220-1226
-
-
Tandan, R.1
-
27
-
-
10744222650
-
A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis
-
Northeast ALS Consortium
-
CudkowiczME, et al.; Northeast ALS Consortium (2003) A randomized, placebo-controlled trial of topiramate in amyotrophic lateral sclerosis. Neurology 61(4):456-464.
-
(2003)
Neurology
, vol.61
, Issue.4
, pp. 456-464
-
-
Cudkowicz, M.E.1
-
28
-
-
0025320647
-
The regulation and modulation of pH in the nervous system
-
Chesler M (1990) The regulation and modulation of pH in the nervous system. Prog Neurobiol 34(5):401-427.
-
(1990)
Prog Neurobiol
, vol.34
, Issue.5
, pp. 401-427
-
-
Chesler, M.1
-
29
-
-
33847701197
-
Respiratory impairment in a mouse model of amyotrophic lateral sclerosis
-
Tankersley CG, Haenggeli C, Rothstein JD (2007) Respiratory impairment in a mouse model of amyotrophic lateral sclerosis. J Appl Physiol 102(3):926-932.
-
(2007)
J Appl Physiol
, vol.102
, Issue.3
, pp. 926-932
-
-
Tankersley, C.G.1
Haenggeli, C.2
Rothstein, J.D.3
-
30
-
-
66149099232
-
Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: Mechanisms of regulation, measurement, and interpretation
-
Ainslie PN, Duffin J (2009) Integration of cerebrovascular CO2 reactivity and chemoreflex control of breathing: Mechanisms of regulation, measurement, and interpretation. Am J Physiol Regul Integr Comp Physiol 296(5):R1473-R1495.
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.296
, Issue.5
-
-
Ainslie, P.N.1
Duffin, J.2
-
31
-
-
41149097086
-
ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
-
Zhong Z, et al. (2008) ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration. Nat Neurosci 11(4):420-422.
-
(2008)
Nat Neurosci
, vol.11
, Issue.4
, pp. 420-422
-
-
Zhong, Z.1
-
32
-
-
84857790779
-
Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice
-
Miyazaki K, et al. (2012) Early and progressive impairment of spinal blood flow-glucose metabolism coupling in motor neuron degeneration of ALS model mice. J Cereb Blood Flow Metab 32(3):456-467.
-
(2012)
J Cereb Blood Flow Metab
, vol.32
, Issue.3
, pp. 456-467
-
-
Miyazaki, K.1
-
33
-
-
82655173728
-
Disease progression in a mouse model of amyotrophic lateral sclerosis: The influence of chronic stress and corticosterone
-
Fidler JA, et al. (2011) Disease progression in a mouse model of amyotrophic lateral sclerosis: The influence of chronic stress and corticosterone. FASEB J 25(12):4369-4377.
-
(2011)
FASEB J
, vol.25
, Issue.12
, pp. 4369-4377
-
-
Fidler, J.A.1
-
34
-
-
51349120583
-
Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS
-
Chang Y, et al. (2008) Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS. PLoS ONE 3(8):e2849.
-
(2008)
PLoS ONE
, vol.3
, Issue.8
-
-
Chang, Y.1
-
35
-
-
0025753891
-
Ischemic brain slice glucose utilization: Effects of slice thickness, acidosis, and K+
-
Newman GC, Hospod FE, Schissel SL (1991) Ischemic brain slice glucose utilization: Effects of slice thickness, acidosis, and K+. J Cereb Blood Flow Metab 11(3):398-406.
-
(1991)
J Cereb Blood Flow Metab
, vol.11
, Issue.3
, pp. 398-406
-
-
Newman, G.C.1
Hospod, F.E.2
Schissel, S.L.3
-
36
-
-
79851508750
-
Control of MCT1 function in cerebrovascular endothelial cells by intracellular pH
-
Uhernik AL, Tucker C, Smith JP (2011) Control of MCT1 function in cerebrovascular endothelial cells by intracellular pH. Brain Res 1376:10-22.
-
(2011)
Brain Res
, vol.1376
, pp. 10-22
-
-
Uhernik, A.L.1
Tucker, C.2
Smith, J.P.3
-
37
-
-
0023636605
-
Lowered cerebral glucose utilization in amyotrophic lateral sclerosis
-
Dalakas MC, Hatazawa J, Brooks RA, Di Chiro G (1987) Lowered cerebral glucose utilization in amyotrophic lateral sclerosis. Ann Neurol 22(5):580-586.
-
(1987)
Ann Neurol
, vol.22
, Issue.5
, pp. 580-586
-
-
Dalakas, M.C.1
Hatazawa, J.2
Brooks, R.A.3
Di Chiro, G.4
-
38
-
-
33744816535
-
Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS
-
Browne SE, et al. (2006) Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS. Neurobiol Dis 22(3):599-610.
-
(2006)
Neurobiol Dis
, vol.22
, Issue.3
, pp. 599-610
-
-
Browne, S.E.1
-
39
-
-
0025548045
-
-
Godoy JM, Skacel M, Lima JM, Andrade CM (1990) Arqu Neuro-Psiqu 48(4):473-477.
-
(1990)
Arqu Neuro-Psiqu
, vol.48
, Issue.4
, pp. 473-477
-
-
Godoy, J.M.1
Skacel, M.2
Lima, J.M.3
Andrade, C.M.4
-
40
-
-
77954659191
-
Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease
-
Ashe KM, et al. (2010) Inhibition of glycogen biosynthesis via mTORC1 suppression as an adjunct therapy for Pompe disease. Mol Genet Metab 100(4):309-315.
-
(2010)
Mol Genet Metab
, vol.100
, Issue.4
, pp. 309-315
-
-
Ashe, K.M.1
-
41
-
-
79953647105
-
Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis
-
Zhang X, et al. (2011) Rapamycin treatment augments motor neuron degeneration in SOD1(G93A) mouse model of amyotrophic lateral sclerosis. Autophagy 7(4):412-425.
-
(2011)
Autophagy
, vol.7
, Issue.4
, pp. 412-425
-
-
Zhang, X.1
-
43
-
-
34249980373
-
An immunological epitope selective for pathological monomermisfolded SOD1 in ALS
-
Rakhit R, et al. (2007) An immunological epitope selective for pathological monomermisfolded SOD1 in ALS. Nat Med 13(6):754-759.
-
(2007)
Nat Med
, vol.13
, Issue.6
, pp. 754-759
-
-
Rakhit, R.1
-
44
-
-
35348874857
-
Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models
-
Zetterström P, et al. (2007) Soluble misfolded subfractions of mutant superoxide dismutase-1s are enriched in spinal cords throughout life in murine ALS models. Proc Natl Acad Sci USA 104(35):14157-14162.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, Issue.35
, pp. 14157-14162
-
-
Zetterström, P.1
-
45
-
-
0029134532
-
Amyotrophic lateral sclerosis: Predictors for prolongation of life by noninvasive respiratory aids
-
Bach JR (1995) Amyotrophic lateral sclerosis: Predictors for prolongation of life by noninvasive respiratory aids. Arch Phys Med Rehabil 76(9):828-832.
-
(1995)
Arch Phys Med Rehabil
, vol.76
, Issue.9
, pp. 828-832
-
-
Bach, J.R.1
-
46
-
-
77951819187
-
Prolonging survival in amyotrophic lateral sclerosis: Efficacy of noninvasive ventilation and uncuffed tracheostomy tubes
-
Sancho J, Servera E, Bañuls P, Marín J (2010) Prolonging survival in amyotrophic lateral sclerosis: Efficacy of noninvasive ventilation and uncuffed tracheostomy tubes. Am J Phys Med Rehabil 89(5):407-411.
-
(2010)
Am J Phys Med Rehabil
, vol.89
, Issue.5
, pp. 407-411
-
-
Sancho, J.1
Servera, E.2
Bañuls, P.3
Marín, J.4
|