Severely increased risk of amyotrophic lateral sclerosis among Italian professional football players

Brain

Volumn 128, Issue 3, 2005, Pages 472-476

  Chiò, Adriano ^c,d   Benzi, Gianmartino ^a   Dossena, Maurizia ^a   Mutani, Roberto ^c   Mora, Gabriele ^b  

^a UNIVERSITY OF PAVIA   (Italy)

^b IRCCS   (Italy)

^c UNIVERSITY OF TURIN   (Italy)

^d Department of Neuroscience ^*  (Italy)

Author keywords

Amyotrophic lateral sclerosis; Football; Risk factor

Indexed keywords

ADULT; AGED; AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CALCULATION; CLINICAL FEATURE; COHORT ANALYSIS; CONFIDENCE INTERVAL; CONTROLLED STUDY; FOLLOW UP; FOOTBALL; HUMAN; ITALY; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL HAZARD; PRIORITY JOURNAL; RISK ASSESSMENT; RISK FACTOR; SCORING SYSTEM; SPORT; STANDARDIZED MORBIDITY RATIO; ADOLESCENT; INCIDENCE; MIDDLE AGED; OCCUPATIONAL DISEASE; ONSET AGE; RETROSPECTIVE STUDY; TIME;

ADOLESCENT; ADULT; AGE OF ONSET; AGED; AMYOTROPHIC LATERAL SCLEROSIS; HUMANS; INCIDENCE; ITALY; MALE; MIDDLE AGED; OCCUPATIONAL DISEASES; RETROSPECTIVE STUDIES; RISK FACTORS; SOCCER; TIME FACTORS;

EID: 15044342282     PISSN: 00068950     EISSN: None     Source Type: Journal    
DOI: 10.1093/brain/awh373     Document Type: Article

References (19)

1. Armon C. An evidence-based medicine approach to the evaluation of the role of exogenous risk factors in sporadic amyotrophic lateral sclerosis. Neuroepidemiology 2003; 22: 217-28.
2. Armon C, Daube JR, O'Brien PC, Kurland LT, Mulder DW. When is an apparent excess of neurologic cases epidemiologically significant? Neurology 1991; 41: 1713-8.
3. Brooks BR, Miller RG, Swash M, Munsat TL, World Federation of Neurology Research Group on Motor Neuron Diseases. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1: 293-9.
4. Chiö A, Mora G, Leone M, Mazzini L, Cocito D, Giordana MT, et al. Early symptom progression rate is related to ALS outcome: a prospective population-based study. Neurology 2002; 59: 99-103.
5. Kurland LT, Radhakrishnan K, Smith GE, Armon C, Nemetz PN. Mechanical traumas as a risk factor in classic amyotrophic lateral sclerosis: lack of epidemiologic evidence. J Neural Sci 1992; 113: 133-43.
6. Kurtzke JF, Beebe GW. Epidemiology of amyotrophic lateral sclerosis: I. A case-control comparison based on ALS deaths. Neurology 1980; 30: 453-62.
7. Logroscino G, Palagano G, Zoccolella S, Beghi E. Incidence of amyotrophic lateral sclerosis in Southern Italy. Neuroepidemiology 1999; 18: 327-8.
8. Longstreth WT, JR, McGuire V, Koepsell TD, Wang Y, van Belle G. Risk of amyotrophic lateral sclerosis and history of physical activity. A population-based case-control study. Arch Neurol 1998; 55: 201-6.
9. Mahoney DJ, Rodriguez C, Devries M, Yasuda N, Tarnopolsky MA. Effects of high-intensity endurance exercise training in the G83A mouse model of amyotrophic lateral sclerosis. Muscle Nerve 2004; 29: 656-62.
10. Matser JT, Kessels AG, Lezak MD, Troost J. A dose-response relation of headers and concussions with cognitive impairment in professional football players. J Clin Exp Neuropsychol 2001; 23: 770-4.
11. Mitchell JD. Amyotrophic lateral sclerosis: toxins and environment. Amyotroph Lateral Scler Other Motor Neuron Disord 2000; 1: 235-50.
12. Piazza O, Sirén A-L, Ehrenreich H. Football, neurotrauma and amyotrophic lateral sclerosis: is there a connection? Curr Med Res Opin 2004; 20: 505-8.
13. Piemonte and Valle d'Aosta Register for ALS (PARALS). Incidence of ALS in Italy. Evidence for a uniform frequency in Western countries. Neurology 2001; 56: 239-44.
14. Rowland LP, Schneider NA. Amyotrophic lateral sclerosis. N Engl J Med 2001; 344: 1688-700.
15. Scarmeas N, Shih T, Stern Y, Ottman R, Rowland LP. Premorbid weight, body mass and varsity athletics in ALS. Neurology 2002; 59: 773-5.
16. Schoenberg BS. Calculating confidence intervals for rates and ratios. Neuroepidemiology 1983; 2: 257-65.
17. Strickland D, Smith SA, Dolliff G, Goldman L. Roelofs RI. Physical activity, trauma and ALS: a case-control study. Acta Neurol Scand 1996; 94: 45-50.
18. Traynor BJ, Codd MB, Corr B, Forde C, Frost E, Hardiman O. Incidence and prevalence of ALS in Ireland, 1995-1997: a population-based study. Neurology 1999; 52: 504-9.
19. Veldink JH, Bar PR, Joosten EA, Otten M, Wokke JD, van den Berg LH. Sexual differences in onset of disease and response to exercise in a transgenic model of ALS. Neuromusc Dis 2003; 13: 4737-43.