Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation

Nature Communications

Volumn 7, Issue , 2016, Pages

  Choi, Won Hoon ^a   De Poot, Stefanie A H ^b   Lee, Jung Hoon ^a   Kim, Ji Hyeon ^a   Han, Dong Hoon ^a   Kim, Yun Kyung ^c   Finley, Daniel ^b   Lee, Min Jae ^a  

^a Seoul National University   (South Korea)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Korea Institute of Science and Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

MUTANT PROTEIN; PROTEASOME; TAU PROTEIN; UBIQUITIN; PROTEIN;

CELLS AND CELL COMPONENTS; HYDROLYSIS; MAMMAL; MUTATION; PROTEIN; PROTEOMICS; TOXIN; TRANSLOCATION;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL MUTANT; CHANNEL GATING; CONTROLLED STUDY; ENZYMATIC DEGRADATION; GENE DELETION; HYDROLYSIS; MAMMAL; NONHUMAN; OXIDATIVE STRESS; PROTEIN AGGREGATION; PROTEIN DEGRADATION; PROTEOMICS; CELL LINE; CHEMISTRY; GENETICS; HUMAN; METABOLISM; MUTATION; PROTEIN TERTIARY STRUCTURE;

MAMMALIA;

CELL LINE; HUMANS; HYDROLYSIS; MUTATION; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN STRUCTURE, TERTIARY; PROTEINS; PROTEOLYSIS; UBIQUITIN;

EID: 84960517495     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms10963     Document Type: Article

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