Facilitated tau degradation by USP14 aptamers via enhanced proteasome activity

Scientific Reports

Volumn 5, Issue , 2015, Pages

  Lee, Jung Hoon ^a   Shin, Seung Kyun ^b   Jiang, Yanxialei ^b   Choi, Won Hoon ^a   Hong, Chaesun ^c   Kim, Dong Eun ^c   Lee, Min Jae ^a  

^a Seoul National University   (South Korea)

^b Kyung Hee University   (South Korea)

^c Konkuk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

APTAMER; PROTEASOME; PROTEIN BINDING; RECOMBINANT PROTEIN; TAU PROTEIN; UBIQUITIN THIOLESTERASE; USP14 PROTEIN, HUMAN;

CELL CULTURE; CELL LINE; CHEMISTRY; CONFORMATION; ENZYME SPECIFICITY; GENETICS; HUMAN; METABOLISM; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN DEGRADATION; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT APTAMER TECHNIQUE; UBIQUITINATION;

APTAMERS, NUCLEOTIDE; BASE SEQUENCE; CELL LINE; CELLS, CULTURED; HUMANS; NUCLEIC ACID CONFORMATION; OXIDATIVE STRESS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEIN BINDING; PROTEOLYSIS; RECOMBINANT PROTEINS; SELEX APTAMER TECHNIQUE; SUBSTRATE SPECIFICITY; TAU PROTEINS; UBIQUITIN THIOLESTERASE; UBIQUITINATION;

EID: 84930651495     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep10757     Document Type: Article

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