Overexpression of Metallothionein-1 Modulates the Phenotype of the Tg2576 Mouse Model of Alzheimer's Disease

Journal of Alzheimer's Disease

Volumn 51, Issue 1, 2016, Pages 81-95

  Manso, Yasmina ^a,d   Comes, Gemma ^a   López Ramos, Juan C ^b   Belfiore, Mónica ^a   Molinero, Amalia ^a   Giralt, Mercedes ^a   Carrasco, Javier ^a   Adlard, Paul A ^c   Bush, Ashley I ^c   Delgado García, José María ^b   Hidalgo, Juan ^a  

^a UNIVERSITAT AUTÒNOMA DE BARCELONA   (Spain)

^b UNIVERSIDAD PABLO DE OLAVIDE   (Spain)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Alzheimer' disease; amyloid plaques; behavior; body weight; gliosis; metallothionein 1; metals; survival; Tg2576

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; MESSENGER RNA; METALLOTHIONEIN I; AMYLOID PRECURSOR PROTEIN; MATRIX METALLOPROTEINASE 16; METALLOTHIONEIN; MT1A PROTEIN, HUMAN;

ADULTHOOD; ALZHEIMER DISEASE; AMYLOID PLAQUE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; BEHAVIOR; BRAIN CORTEX; CONTROLLED STUDY; EXPLORATORY BEHAVIOR; EYE BLINK TEST; FEMALE; HIPPOCAMPUS; LEARNING; MALE; MORRIS WATER MAZE TEST; MORTALITY; MOUSE; MOUSE MODEL; MUTATION; NEUROLOGIC EXAMINATION; NONHUMAN; PERINATAL MORTALITY; PERINATAL PERIOD; PHENOTYPE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN FUNCTION; SPATIAL LEARNING; SURVIVAL; WEIGHT REDUCTION; AGE; ANIMAL; C57BL MOUSE; COMPLICATION; DISEASE MODEL; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MAZE TEST; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY; PSYCHOMOTOR DISORDERS; TRANSGENIC MOUSE;

AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; ANXIETY; DISEASE MODELS, ANIMAL; EXPLORATORY BEHAVIOR; FEMALE; GENE EXPRESSION REGULATION; HUMANS; MALE; MATRIX METALLOPROTEINASE 16; MAZE LEARNING; METALLOTHIONEIN; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR ACTIVITY; MUTATION; PHENOTYPE; PSYCHOMOTOR DISORDERS;

EID: 84960080530     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-151025     Document Type: Article

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