-
1
-
-
0037423247
-
A war on obesity, not the obese
-
Friedman, J. M. (2003) A war on obesity, not the obese. Science 299, 856-858
-
(2003)
Science
, vol.299
, pp. 856-858
-
-
Friedman, J.M.1
-
2
-
-
3042621978
-
The human obesity gene map: The 2003 update
-
Snyder, E. E., Walts, B., Perusse, L., Chagnon, Y. C., Weisnagel, S. J., Rankinen, T., and Bouchard, C. (2004) The human obesity gene map: the 2003 update. Obes. Res. 12, 369-439
-
(2004)
Obes. Res.
, vol.12
, pp. 369-439
-
-
Snyder, E.E.1
Walts, B.2
Perusse, L.3
Chagnon, Y.C.4
Weisnagel, S.J.5
Rankinen, T.6
Bouchard, C.7
-
3
-
-
0036152683
-
Interleukin-6-deficient mice develop mature-onset obesity
-
Wallenius, V., Wallenius, K., Ahren, B., Rudling, M., Carlsten, H., Dickson, S. L., Ohlsson, C., and Jansson, J. O. (2002) Interleukin-6-deficient mice develop mature-onset obesity. Nat. Med. 8, 75-79
-
(2002)
Nat. Med.
, vol.8
, pp. 75-79
-
-
Wallenius, V.1
Wallenius, K.2
Ahren, B.3
Rudling, M.4
Carlsten, H.5
Dickson, S.L.6
Ohlsson, C.7
Jansson, J.O.8
-
4
-
-
33745009509
-
Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance
-
Netea, M. G., Joosten, L. A., Lewis, E., Jensen, D. R., Voshol, P. J., Kullberg, B. J., Tack, C. J., van Krieken, H., Kim, S. H., Stalenhoef, A. F., van de Loo, F. A., Verschueren, I., Pulawa, L., Akira, S., Eckel, R. H., Dinarello, C. A., van den Berg, W., and van der Meer, J. W. (2006) Deficiency of interleukin-18 in mice leads to hyperphagia, obesity and insulin resistance. Nat. Med. 12, 650-656
-
(2006)
Nat. Med.
, vol.12
, pp. 650-656
-
-
Netea, M.G.1
Joosten, L.A.2
Lewis, E.3
Jensen, D.R.4
Voshol, P.J.5
Kullberg, B.J.6
Tack, C.J.7
Van Krieken, H.8
Kim, S.H.9
Stalenhoef, A.F.10
Van De Loo, F.A.11
Verschueren, I.12
Pulawa, L.13
Akira, S.14
Eckel, R.H.15
Dinarello, C.A.16
Van Den Berg, W.17
Van Der Meer, J.W.18
-
5
-
-
20244380182
-
Angiopoietin-related growth factor antagonizes obesity and insulin resistance
-
Oike, Y., Akao, M., Yasunaga, K., Yamauchi, T., Morisada, T., Ito, Y., Urano, T., Kimura, Y., Kubota, Y., Maekawa, H., Miyamoto, T., Miyata, K., Matsumoto, S., Sakai, J., Nakagata, N., Takeya, M., Koseki, H., Ogawa, Y., Kadowaki, T., and Suda, T. (2005) Angiopoietin-related growth factor antagonizes obesity and insulin resistance. Nat. Med. 11, 400-408
-
(2005)
Nat. Med.
, vol.11
, pp. 400-408
-
-
Oike, Y.1
Akao, M.2
Yasunaga, K.3
Yamauchi, T.4
Morisada, T.5
Ito, Y.6
Urano, T.7
Kimura, Y.8
Kubota, Y.9
Maekawa, H.10
Miyamoto, T.11
Miyata, K.12
Matsumoto, S.13
Sakai, J.14
Nakagata, N.15
Takeya, M.16
Koseki, H.17
Ogawa, Y.18
Kadowaki, T.19
Suda, T.20
more..
-
6
-
-
34447116241
-
Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome
-
Kuo, L. E., Kitlinska, J. B., Tilan, J. U., Li, L., Baker, S. B., Johnson, M. D., Lee, E. W., Burnett, M. S., Fricke, S. T., Kvetnansky, R., Herzog, H., and Zukowska, Z. (2007) Neuropeptide Y acts directly in the periphery on fat tissue and mediates stress-induced obesity and metabolic syndrome. Nat. Med. 13, 803-811
-
(2007)
Nat. Med.
, vol.13
, pp. 803-811
-
-
Kuo, L.E.1
Kitlinska, J.B.2
Tilan, J.U.3
Li, L.4
Baker, S.B.5
Johnson, M.D.6
Lee, E.W.7
Burnett, M.S.8
Fricke, S.T.9
Kvetnansky, R.10
Herzog, H.11
Zukowska, Z.12
-
7
-
-
67449091887
-
Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion
-
Lee, H., Lee, Y. J., Choi, H., Ko, E. H., and Kim, J. W. (2009) Reactive oxygen species facilitate adipocyte differentiation by accelerating mitotic clonal expansion. J. Biol. Chem. 284, 10601-10609
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 10601-10609
-
-
Lee, H.1
Lee, Y.J.2
Choi, H.3
Ko, E.H.4
Kim, J.W.5
-
8
-
-
51449123847
-
Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells
-
Sekiya, M., Hiraishi, A., Touyama, M., and Sakamoto, K. (2008) Oxidative stress induced lipid accumulation via SREBP1c activation in HepG2 cells. Biochem. Biophys. Res. Commun. 375, 602-607
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.375
, pp. 602-607
-
-
Sekiya, M.1
Hiraishi, A.2
Touyama, M.3
Sakamoto, K.4
-
9
-
-
5644231992
-
Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
-
Özcan, U., Cao, Q., Yilmaz, E., Lee, A. H., Iwakoshi, N. N., Ozdelen, E., Tuncman, G., Gorgun, C., Glimcher, L. H., and Hotamisligil, G. S. (2004) Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-461
-
(2004)
Science
, vol.306
, pp. 457-461
-
-
Özcan, U.1
Cao, Q.2
Yilmaz, E.3
Lee, A.H.4
Iwakoshi, N.N.5
Ozdelen, E.6
Tuncman, G.7
Gorgun, C.8
Glimcher, L.H.9
Hotamisligil, G.S.10
-
10
-
-
85030434746
-
Increased oxidative stress in obesity and its impact on metabolic syndrome
-
Furukawa, S., Fujita, T., Shimabukuro, M., Iwaki, M., Yamada, Y., Nakajima, Y., Nakayama, O., Makishima, M., Matsuda, M., and Shimomura, I. (2004) Increased oxidative stress in obesity and its impact on metabolic syndrome. J. Clin. Invest. 114, 1752-1761
-
(2004)
J. Clin. Invest.
, vol.114
, pp. 1752-1761
-
-
Furukawa, S.1
Fujita, T.2
Shimabukuro, M.3
Iwaki, M.4
Yamada, Y.5
Nakajima, Y.6
Nakayama, O.7
Makishima, M.8
Matsuda, M.9
Shimomura, I.10
-
11
-
-
0036239958
-
Recent studies on metallothionein: Protection against toxicity of heavy metals and oxygen free radicals
-
Sato, M., and Kondoh, M. (2002) Recent studies on metallothionein: protection against toxicity of heavy metals and oxygen free radicals. Tohoku J. Exp. Med. 196, 9-22
-
(2002)
Tohoku J. Exp. Med.
, vol.196
, pp. 9-22
-
-
Sato, M.1
Kondoh, M.2
-
12
-
-
0034012029
-
Metallothionein expression in animals: A physiological perspective on function
-
Davis, S. R., and Cousins, R. J. (2000) Metallothionein expression in animals: a physiological perspective on function. J. Nutr. 130, 1085-1088
-
(2000)
J. Nutr.
, vol.130
, pp. 1085-1088
-
-
Davis, S.R.1
Cousins, R.J.2
-
13
-
-
36549005537
-
Zinc, metallothioneins, and longevity-effect of zinc supplementation: Zincage study
-
Mocchegiani, E., Giacconi, R., Cipriano, C., Costarelli, L., Muti, E., Tesei, S., Giuli, C., Papa, R., Marcellini, F., Mariani, E., Rink, L., Herbein, G., Varin, A., Fulop, T., Monti, D., Jajte, J., Dedoussis, G., Gonos, E. S., Trougakos, I. P., and Malavolta, M. (2007) Zinc, metallothioneins, and longevity-effect of zinc supplementation: zincage study. Ann. N. Y. Acad. Sci. 1119, 129-146
-
(2007)
Ann. N. Y. Acad. Sci.
, vol.1119
, pp. 129-146
-
-
Mocchegiani, E.1
Giacconi, R.2
Cipriano, C.3
Costarelli, L.4
Muti, E.5
Tesei, S.6
Giuli, C.7
Papa, R.8
Marcellini, F.9
Mariani, E.10
Rink, L.11
Herbein, G.12
Varin, A.13
Fulop, T.14
Monti, D.15
Jajte, J.16
Dedoussis, G.17
Gonos, E.S.18
Trougakos, I.P.19
Malavolta, M.20
more..
-
14
-
-
0018223827
-
Biological function of metallothionein. V. Its induction in rats by various stresses
-
Oh, S. H., Deagen, J. T., Whanger, P. D., and Weswig, P. H. (1978) Biological function of metallothionein. V. Its induction in rats by various stresses. Am. J. Physiol. 234, E282-E285
-
(1978)
Am. J. Physiol.
, vol.234
-
-
Oh, S.H.1
Deagen, J.T.2
Whanger, P.D.3
Weswig, P.H.4
-
15
-
-
0029948862
-
Cold-induced expression of the metallothionein-1 gene in brown adipose tissue of rats
-
Beattie, J. H., Black, D. J., Wood, A. M., and Trayhurn, P. (1996) Cold-induced expression of the metallothionein-1 gene in brown adipose tissue of rats. Am. J. Physiol. 270, R971-R977
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Beattie, J.H.1
Black, D.J.2
Wood, A.M.3
Trayhurn, P.4
-
16
-
-
0035988689
-
Metallothionein gene expression in human adipose tissue from lean and obese subjects
-
Do, M. S., Nam, S. Y., Hong, S. E., Kim, K. W., Duncan, J. S., Beattie, J. H., and Trayhurn, P. (2002) Metallothionein gene expression in human adipose tissue from lean and obese subjects. Horm. Metab. Res. 34, 348-351
-
(2002)
Horm. Metab. Res.
, vol.34
, pp. 348-351
-
-
Do, M.S.1
Nam, S.Y.2
Hong, S.E.3
Kim, K.W.4
Duncan, J.S.5
Beattie, J.H.6
Trayhurn, P.7
-
17
-
-
0033637053
-
Metallothionein gene expression and secretion in white adipose tissue
-
Trayhurn, P., Duncan, J. S., Wood, A. M., and Beattie, J. H. (2000) Metallothionein gene expression and secretion in white adipose tissue. Am. J. Physiol. 279, R2329-R2335
-
(2000)
Am. J. Physiol.
, vol.279
-
-
Trayhurn, P.1
Duncan, J.S.2
Wood, A.M.3
Beattie, J.H.4
-
18
-
-
0035956862
-
Zinc metallothionein imported into liver mitochondria modulates respiration
-
Ye, B., Maret, W., and Vallee, B. L. (2001) Zinc metallothionein imported into liver mitochondria modulates respiration. Proc. Natl. Acad. Sci. U. S. A. 98, 2317-2322
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 2317-2322
-
-
Ye, B.1
Maret, W.2
Vallee, B.L.3
-
19
-
-
20444403004
-
Gene expression profiles in the liver and kidney of metallothionein-null mice
-
Miura, N., and Koizumi, S. (2005) Gene expression profiles in the liver and kidney of metallothionein-null mice. Biochem. Biophys. Res. Commun. 332, 949-955
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 949-955
-
-
Miura, N.1
Koizumi, S.2
-
20
-
-
0031892092
-
Obesity and hyperleptinemia in metallothionein (-I and -II) null mice
-
Beattie, J. H., Wood, A. M., Newman, A. M., Bremner, I., Choo, K. H., Michalska, A. E., Duncan, J. S., and Trayhurn, P. (1998) Obesity and hyperleptinemia in metallothionein (-I and -II) null mice. Proc. Natl. Acad. Sci. U. S. A. 95, 358-363
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 358-363
-
-
Beattie, J.H.1
Wood, A.M.2
Newman, A.M.3
Bremner, I.4
Choo, K.H.5
Michalska, A.E.6
Duncan, J.S.7
Trayhurn, P.8
-
21
-
-
0032555204
-
The elusive function of metallothioneins
-
Palmiter, R. D. (1998) The elusive function of metallothioneins. Proc. Natl. Acad. Sci. U. S. A. 95, 8428-8430
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 8428-8430
-
-
Palmiter, R.D.1
-
22
-
-
33749427563
-
Involvement of oxidative stress in the synthesis of metallothionein induced by mitochondrial inhibitors
-
Futakawa, N., Kondoh, M., Ueda, S., Higashimoto, M., Takiguchi, M., Suzuki, S., and Sato, M. (2006) Involvement of oxidative stress in the synthesis of metallothionein induced by mitochondrial inhibitors. Biol. Pharm. Bull. 29, 2016-2020
-
(2006)
Biol. Pharm. Bull.
, vol.29
, pp. 2016-2020
-
-
Futakawa, N.1
Kondoh, M.2
Ueda, S.3
Higashimoto, M.4
Takiguchi, M.5
Suzuki, S.6
Sato, M.7
-
23
-
-
1342264204
-
Induction of hepatic metallothionein synthesis by endoplasmic reticulum stress in mice
-
Kondoh, M., Tsukada, M., Kuronaga, M., Higashimoto, M., Takiguchi, M., Himeno, S., Watanabe, Y., and Sato, M. (2004) Induction of hepatic metallothionein synthesis by endoplasmic reticulum stress in mice. Toxicol. Lett. 148, 133-139
-
(2004)
Toxicol. Lett.
, vol.148
, pp. 133-139
-
-
Kondoh, M.1
Tsukada, M.2
Kuronaga, M.3
Higashimoto, M.4
Takiguchi, M.5
Himeno, S.6
Watanabe, Y.7
Sato, M.8
-
24
-
-
0032558725
-
Leptin and the regulation of body weight in mammals
-
Friedman, J. M., and Halaas, J. L. (1998) Leptin and the regulation of body weight in mammals. Nature 395, 763-770
-
(1998)
Nature
, vol.395
, pp. 763-770
-
-
Friedman, J.M.1
Halaas, J.L.2
-
25
-
-
0034214246
-
Transcriptional regulation of adipogenesis
-
Rosen, E. D., Walkey, C. J., Puigserver, P., and Spiegelman, B. M. (2000) Transcriptional regulation of adipogenesis. Genes Dev. 14, 1293-1307
-
(2000)
Genes Dev.
, vol.14
, pp. 1293-1307
-
-
Rosen, E.D.1
Walkey, C.J.2
Puigserver, P.3
Spiegelman, B.M.4
-
26
-
-
11144346135
-
Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size
-
Takahashi, M., Kamei, Y., and Ezaki, O. (2005) Mest/Peg1 imprinted gene enlarges adipocytes and is a marker of adipocyte size. Am. J. Physiol. Endocrinol. Metab. 288, E117-E124
-
(2005)
Am. J. Physiol. Endocrinol. Metab.
, vol.288
-
-
Takahashi, M.1
Kamei, Y.2
Ezaki, O.3
-
27
-
-
0027955113
-
Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium
-
Masters, B. A., Kelly, E. J., Quaife, C. J., Brinster, R. L., and Palmiter, R. D. (1994) Targeted disruption of metallothionein I and II genes increases sensitivity to cadmium. Proc. Natl. Acad. Sci. U. S. A. 91, 584-588
-
(1994)
Proc. Natl. Acad. Sci. U. S. A.
, vol.91
, pp. 584-588
-
-
Masters, B.A.1
Kelly, E.J.2
Quaife, C.J.3
Brinster, R.L.4
Palmiter, R.D.5
-
28
-
-
0023411038
-
Proliferation of unilocular fat cells in the primary culture
-
Sugihara, H., Yonemitsu, N., Miyabara, S., and Toda, S. (1987) Proliferation of unilocular fat cells in the primary culture. J. Lipid Res. 28, 1038-1045
-
(1987)
J. Lipid Res.
, vol.28
, pp. 1038-1045
-
-
Sugihara, H.1
Yonemitsu, N.2
Miyabara, S.3
Toda, S.4
-
29
-
-
0035851187
-
PPARgamma: A nuclear regulator of metabolism, differentiation, and cell growth
-
Rosen, E. D., and Spiegelman, B. M. (2001) PPARgamma: a nuclear regulator of metabolism, differentiation, and cell growth. J. Biol. Chem. 276, 37731-37734
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 37731-37734
-
-
Rosen, E.D.1
Spiegelman, B.M.2
-
30
-
-
33646928066
-
Changes in gene expression foreshadow diet-induced obesity in genetically identical mice
-
doi:10.1371/journal.pgen.0020081
-
Koza, R. A., Nikonova, L., Hogan, J., Rim, J. S., Mendoza, T., Faulk, C., Skaf, J., and Kozak, L. P. (2006) Changes in gene expression foreshadow diet-induced obesity in genetically identical mice. PLoS Genet. 2, e81. doi:10.1371/journal.pgen.0020081
-
(2006)
PLoS Genet.
, vol.2
-
-
Koza, R.A.1
Nikonova, L.2
Hogan, J.3
Rim, J.S.4
Mendoza, T.5
Faulk, C.6
Skaf, J.7
Kozak, L.P.8
-
31
-
-
55549118918
-
Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance
-
Nikonova, L., Koza, R. A., Mendoza, T., Chao, P. M., Curley, J. P., and Kozak, L. P. (2008) Mesoderm-specific transcript is associated with fat mass expansion in response to a positive energy balance. FASEB J. 22, 3925-3937
-
(2008)
FASEB J.
, vol.22
, pp. 3925-3937
-
-
Nikonova, L.1
Koza, R.A.2
Mendoza, T.3
Chao, P.M.4
Curley, J.P.5
Kozak, L.P.6
-
32
-
-
0027204069
-
Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse
-
Michalska, A. E., and Choo, K. H. (1993) Targeting and germ-line transmission of a null mutation at the metallothionein I and II loci in mouse. Proc. Natl. Acad. Sci. U. S. A. 90, 8088-8092
-
(1993)
Proc. Natl. Acad. Sci. U. S. A.
, vol.90
, pp. 8088-8092
-
-
Michalska, A.E.1
Choo, K.H.2
-
33
-
-
0029791412
-
PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene
-
Schoonjans, K., Peinado-Onsurbe, J., Lefebvre, A. M., Heyman, R. A., Briggs, M., Deeb, S., Staels, B., and Auwerx, J. (1996) PPARalpha and PPARgamma activators direct a distinct tissue-specific transcriptional response via a PPRE in the lipoprotein lipase gene. EMBO J. 15, 5336-5348
-
(1996)
EMBO J.
, vol.15
, pp. 5336-5348
-
-
Schoonjans, K.1
Peinado-Onsurbe, J.2
Lefebvre, A.M.3
Heyman, R.A.4
Briggs, M.5
Deeb, S.6
Staels, B.7
Auwerx, J.8
-
34
-
-
0033212964
-
PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance
-
Kubota, N., Terauchi, Y., Miki, H., Tamemoto, H., Yamauchi, T., Komeda, K., Satoh, S., Nakano, R., Ishii, C., Sugiyama, T., Eto, K., Tsubamoto, Y., Okuno, A., Murakami, K., Sekihara, H., Hasegawa, G., Naito, M., Toyoshima, Y., Tanaka, S., Shiota, K., Kitamura, T., Fujita, T., Ezaki, O., Aizawa, S., and Kadowaki, T. (1999) PPAR gamma mediates high-fat diet-induced adipocyte hypertrophy and insulin resistance. Mol. Cell 4, 597-609
-
(1999)
Mol. Cell
, vol.4
, pp. 597-609
-
-
Kubota, N.1
Terauchi, Y.2
Miki, H.3
Tamemoto, H.4
Yamauchi, T.5
Komeda, K.6
Satoh, S.7
Nakano, R.8
Ishii, C.9
Sugiyama, T.10
Eto, K.11
Tsubamoto, Y.12
Okuno, A.13
Murakami, K.14
Sekihara, H.15
Hasegawa, G.16
Naito, M.17
Toyoshima, Y.18
Tanaka, S.19
Shiota, K.20
Kitamura, T.21
Fujita, T.22
Ezaki, O.23
Aizawa, S.24
Kadowaki, T.25
more..
-
35
-
-
20944439189
-
Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance
-
Jones, J. R., Barrick, C., Kim, K. A., Lindner, J., Blondeau, B., Fujimoto, Y., Shiota, M., Kesterson, R. A., Kahn, B. B., and Magnuson, M. A. (2005) Deletion of PPARgamma in adipose tissues of mice protects against high fat diet-induced obesity and insulin resistance. Proc. Natl. Acad. Sci. U. S. A. 102, 6207-6212
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 6207-6212
-
-
Jones, J.R.1
Barrick, C.2
Kim, K.A.3
Lindner, J.4
Blondeau, B.5
Fujimoto, Y.6
Shiota, M.7
Kesterson, R.A.8
Kahn, B.B.9
Magnuson, M.A.10
-
36
-
-
3042745457
-
Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice
-
Guo, K. Y., Halo, P., Leibel, R. L., and Zhang, Y. (2004) Effects of obesity on the relationship of leptin mRNA expression and adipocyte size in anatomically distinct fat depots in mice. Am. J. Physiol. 287, R112-R119
-
(2004)
Am. J. Physiol.
, vol.287
-
-
Guo, K.Y.1
Halo, P.2
Leibel, R.L.3
Zhang, Y.4
-
37
-
-
0034284520
-
Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain
-
Lin, S., Storlien, L. H., and Huang, X. F. (2000) Leptin receptor, NPY, POMC mRNA expression in the diet-induced obese mouse brain. Brain Res. 875, 89-95
-
(2000)
Brain Res.
, vol.875
, pp. 89-95
-
-
Lin, S.1
Storlien, L.H.2
Huang, X.F.3
-
38
-
-
29144510014
-
Fat storage in adipocytes requires inactivation of leptin's paracrine activity: Implications for treatment of human obesity
-
Wang, M. Y., Orci, L., Ravazzola, M., and Unger, R. H. (2005) Fat storage in adipocytes requires inactivation of leptin's paracrine activity: implications for treatment of human obesity. Proc. Natl. Acad. Sci. U. S. A. 102, 18011-18016
-
(2005)
Proc. Natl. Acad. Sci. U. S. A.
, vol.102
, pp. 18011-18016
-
-
Wang, M.Y.1
Orci, L.2
Ravazzola, M.3
Unger, R.H.4
-
39
-
-
0142020848
-
Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats
-
Levin, B. E., Dunn-Meynell, A. A., Ricci, M. R., and Cummings, D. E. (2003) Abnormalities of leptin and ghrelin regulation in obesity-prone juvenile rats. Am. J. Physiol. Endocrinol. Metab. 285, E949-E957
-
(2003)
Am. J. Physiol. Endocrinol. Metab.
, vol.285
-
-
Levin, B.E.1
Dunn-Meynell, A.A.2
Ricci, M.R.3
Cummings, D.E.4
-
40
-
-
19944430402
-
Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
-
Nakatani, Y., Kaneto, H., Kawamori, D., Yoshiuchi, K., Hatazaki, M., Matsuoka, T. A., Ozawa, K., Ogawa, S., Hori, M., Yamasaki, Y., and Matsuhisa, M. (2005) Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J. Biol. Chem. 280, 847-851
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 847-851
-
-
Nakatani, Y.1
Kaneto, H.2
Kawamori, D.3
Yoshiuchi, K.4
Hatazaki, M.5
Matsuoka, T.A.6
Ozawa, K.7
Ogawa, S.8
Hori, M.9
Yamasaki, Y.10
Matsuhisa, M.11
-
41
-
-
3543109122
-
Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function
-
Ellis, C. D., Wang, F., MacDiarmid, C. W., Clark, S., Lyons, T., and Eide, D. J. (2004) Zinc and the Msc2 zinc transporter protein are required for endoplasmic reticulum function. J. Cell Biol. 166, 325-335
-
(2004)
J. Cell Biol.
, vol.166
, pp. 325-335
-
-
Ellis, C.D.1
Wang, F.2
MacDiarmid, C.W.3
Clark, S.4
Lyons, T.5
Eide, D.J.6
-
42
-
-
10044289331
-
Prevention of spontaneous and experimentally induced diabetes in mice with zinc sulfate-enriched drinking water is associated with activation and reduction of NF-kappa B and AP-1 in islets, respectively
-
Schott-Ohly, P., Lgssiar, A., Partke, H. J., Hassan, M., Friesen, N., and Gleichmann, H. (2004) Prevention of spontaneous and experimentally induced diabetes in mice with zinc sulfate-enriched drinking water is associated with activation and reduction of NF-kappa B and AP-1 in islets, respectively. Exp. Biol. Med. (Maywood) 229, 1177-1185
-
(2004)
Exp. Biol. Med. (Maywood)
, vol.229
, pp. 1177-1185
-
-
Schott-Ohly, P.1
Lgssiar, A.2
Partke, H.J.3
Hassan, M.4
Friesen, N.5
Gleichmann, H.6
-
43
-
-
19744375548
-
Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts
-
Feng, W., Cai, J., Pierce, W. M., Franklin, R. B., Maret, W., Benz, F. W., and Kang, Y. J. (2005) Metallothionein transfers zinc to mitochondrial aconitase through a direct interaction in mouse hearts. Biochem. Biophys. Res. Commun. 332, 853-858
-
(2005)
Biochem. Biophys. Res. Commun.
, vol.332
, pp. 853-858
-
-
Feng, W.1
Cai, J.2
Pierce, W.M.3
Franklin, R.B.4
Maret, W.5
Benz, F.W.6
Kang, Y.J.7
-
44
-
-
34548805821
-
Effects of triglyceride on ER stress and insulin resistance
-
Kim, D. S., Jeong, S. K., Kim, H. R., Chae, S. W., and Chae, H. J. (2007) Effects of triglyceride on ER stress and insulin resistance. Biochem. Biophys. Res. Commun. 363, 140-145
-
(2007)
Biochem. Biophys. Res. Commun.
, vol.363
, pp. 140-145
-
-
Kim, D.S.1
Jeong, S.K.2
Kim, H.R.3
Chae, S.W.4
Chae, H.J.5
-
45
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
Zhang, X., Zhang, G., Zhang, H., Karin, M., Bai, H., and Cai, D. (2008) Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity. Cell 135, 61-73
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
46
-
-
0002599375
-
Metallothionein: Molecular evolution and classification
-
(Klaassen, C. D., ed) Birkhäuser Verlag, Basel, Switzerland
-
Binz, P.-A., and Kagi, J. H. R. (1999) Metallothionein: molecular evolution and classification. In Metallothionein IV (Klaassen, C. D., ed) pp. 7-13, Birkhäuser Verlag, Basel, Switzerland
-
(1999)
Metallothionein IV
, pp. 7-13
-
-
Binz, P.-A.1
Kagi, J.H.R.2
-
47
-
-
0031724396
-
Age-dependent changes in metallothionein levels in liver and kidney of the Japanese
-
Yoshida, M., Ohta, H., Yamauchi, Y., Seki, Y., Sagi, M., Yamazaki, K., and Sumi, Y. (1998) Age-dependent changes in metallothionein levels in liver and kidney of the Japanese. Biol. Trace Elem. Res. 63, 167-175
-
(1998)
Biol. Trace Elem. Res.
, vol.63
, pp. 167-175
-
-
Yoshida, M.1
Ohta, H.2
Yamauchi, Y.3
Seki, Y.4
Sagi, M.5
Yamazaki, K.6
Sumi, Y.7
-
48
-
-
33750546251
-
Potential effect on cellular response to cadmium of a single-nucleotide A → G polymorphism in the promoter of the human gene for metallothionein IIA
-
Kita, K., Miura, N., Yoshida, M., Yamazaki, K., Ohkubo, T., Imai, Y., and Naganuma, A. (2006) Potential effect on cellular response to cadmium of a single-nucleotide A → G polymorphism in the promoter of the human gene for metallothionein IIA. Hum. Genet. 120, 553-560
-
(2006)
Hum. Genet.
, vol.120
, pp. 553-560
-
-
Kita, K.1
Miura, N.2
Yoshida, M.3
Yamazaki, K.4
Ohkubo, T.5
Imai, Y.6
Naganuma, A.7
-
49
-
-
0031435337
-
Defective adipocyte differentiation in mice lacking the C/EBP-beta and/or C/EBPdelta gene
-
Tanaka, T., Yoshida, N., Kishimoto, T., and Akira, S. (1997) Defective adipocyte differentiation in mice lacking the C/EBP-beta and/or C/EBPdelta gene. EMBO J. 16, 7432-7443
-
(1997)
EMBO J.
, vol.16
, pp. 7432-7443
-
-
Tanaka, T.1
Yoshida, N.2
Kishimoto, T.3
Akira, S.4
-
50
-
-
0036007024
-
C/EBPalpha induces adipogenesis through PPARgamma: A unified pathway
-
Rosen, E. D., Hsu, C. H., Wang, X., Sakai, S., Freeman, M. W., Gonzalez, F. J., and Spiegelman, B. M. (2002) C/EBPalpha induces adipogenesis through PPARgamma: a unified pathway. Genes Dev. 16, 22-26
-
(2002)
Genes Dev.
, vol.16
, pp. 22-26
-
-
Rosen, E.D.1
Hsu, C.H.2
Wang, X.3
Sakai, S.4
Freeman, M.W.5
Gonzalez, F.J.6
Spiegelman, B.M.7
-
51
-
-
34548434021
-
Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: Role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis
-
Dong, F., Li, Q., Sreejayan, N., Nunn, J. M., and Ren, J. (2007) Metallothionein prevents high-fat diet induced cardiac contractile dysfunction: role of peroxisome proliferator activated receptor gamma coactivator 1alpha and mitochondrial biogenesis. Diabetes 56, 2201-2212
-
(2007)
Diabetes
, vol.56
, pp. 2201-2212
-
-
Dong, F.1
Li, Q.2
Sreejayan, N.3
Nunn, J.M.4
Ren, J.5
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