-
1
-
-
33751074919
-
Metals and Alzheimer's disease
-
Adlard PA, Bush AI (2006) Metals and Alzheimer's disease. J Alzheimers Dis 10:145-163
-
(2006)
J Alzheimers Dis
, vol.10
, pp. 145-163
-
-
Adlard, P.A.1
Bush, A.I.2
-
2
-
-
0031470691
-
Regulation of metallothionein-III (GIF) mRNA in the brain of patients with Alzheimer disease is not impaired
-
Amoureux MC, Van Gool D, Herrero MT, Dom R, Colpaert FC, Pauwels PJ (1997) Regulation of metallothionein-III (GIF) mRNA in the brain of patients with Alzheimer disease is not impaired. Mol Chem Neuropathol 32:101-121
-
(1997)
Mol Chem Neuropathol
, vol.32
, pp. 101-121
-
-
Amoureux, M.C.1
Van Gool, D.2
Herrero, M.T.3
Dom, R.4
Colpaert, F.C.5
Pauwels, P.J.6
-
3
-
-
0032786697
-
Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies EURODEM Incidence Research Group
-
Andersen K, Launer LJ, Dewey ME, Letenneur L, Ott A, Copeland JR, Dartigues JF, Kragh-Sorensen P, Baldereschi M, Brayne C, Lobo A, Martinez-Lage JM, Stijnen T, Hofman A (1999) Gender differences in the incidence of AD and vascular dementia: The EURODEM Studies. EURODEM Incidence Research Group. Neurology 53:1992-1997
-
(1999)
Neurology
, vol.53
, pp. 1992-1997
-
-
Andersen, K.1
Launer, L.J.2
Dewey, M.E.3
Letenneur, L.4
Ott, A.5
Copeland, J.R.6
Dartigues, J.F.7
Kragh-Sorensen, P.8
Baldereschi, M.9
Brayne, C.10
Lobo, A.11
Martinez-Lage, J.M.12
Stijnen, T.13
Hofman, A.14
-
4
-
-
24044479679
-
BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper
-
Angeletti B, Waldron KJ, Freeman KB, Bawagan H, Hussain I, Miller CC, Lau KF, Tennant ME, Dennison C, Robinson NJ, Dingwall C (2005) BACE1 cytoplasmic domain interacts with the copper chaperone for superoxide dismutase-1 and binds copper. J Biol Chem 280:17930-17937
-
(2005)
J Biol Chem
, vol.280
, pp. 17930-17937
-
-
Angeletti, B.1
Waldron, K.J.2
Freeman, K.B.3
Bawagan, H.4
Hussain, I.5
Miller, C.C.6
Lau, K.F.7
Tennant, M.E.8
Dennison, C.9
Robinson, N.J.10
Dingwall, C.11
-
5
-
-
0035689651
-
Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: Task specificity and correlations between Abeta deposition and spatial memory
-
Arendash GW, Gordon MN, Diamond DM, Austin LA, Hatcher JM, Jantzen P, DiCarlo G, Wilcock D, Morgan D (2001) Behavioral assessment of Alzheimer's transgenic mice following long-term Abeta vaccination: task specificity and correlations between Abeta deposition and spatial memory. DNA Cell Biol 20:737-744
-
(2001)
DNA Cell Biol
, vol.20
, pp. 737-744
-
-
Arendash, G.W.1
Gordon, M.N.2
Diamond, D.M.3
Austin, L.A.4
Hatcher, J.M.5
Jantzen, P.6
Dicarlo, G.7
Wilcock, D.8
Morgan, D.9
-
6
-
-
0030781471
-
Astrocyte metallothioneins (MTs) and their neuroprotective role
-
Aschner M (1997) Astrocyte metallothioneins (MTs) and their neuroprotective role. Ann N Y Acad Sci 825:334-347
-
(1997)
Ann N y Acad Sci
, vol.825
, pp. 334-347
-
-
Aschner, M.1
-
7
-
-
20344371487
-
Sex differences in the clinical manifestations of Alzheimer disease pathology
-
Barnes LL, Wilson RS, Bienias JL, Schneider JA, Evans DA, BennettDA(2005) Sex differences in the clinical manifestations of Alzheimer disease pathology. Arch Gen Psychiatry 62:685-691
-
(2005)
Arch Gen Psychiatry
, vol.62
, pp. 685-691
-
-
Barnes, L.L.1
Wilson, R.S.2
Bienias, J.L.3
Schneider, J.A.4
Evans, D.A.5
Bennett, D.A.6
-
8
-
-
10744226316
-
Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice
-
Bayer TA, Scha;fer S, Simons A, Kemmling A, Kamer T, Tepest R, Eckert A, Schu;ssel K, Eikenberg O, Sturchler-Pierrat C, Abramowski D, Staufenbiel M, Multhaup G (2003) Dietary Cu stabilizes brain superoxide dismutase 1 activity and reduces amyloid Abeta production in APP23 transgenic mice. Proc Natl Acad Sci USA 100:14187-14192
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14187-14192
-
-
Bayer, T.A.1
Schafer, S.2
Simons, A.3
Kemmling, A.4
Kamer, T.5
Tepest, R.6
Eckert, A.7
Schussel, K.8
Eikenberg, O.9
Sturchler-Pierrat, C.10
Abramowski, D.11
Staufenbiel, M.12
Multhaup, G.13
-
9
-
-
1242341923
-
Incipient Alzheimer's disease: Microarray correlation analyses reveal major transcriptional and tumor suppressor responses
-
Blalock EM, Geddes JW, Chen KC, Porter NM, Markesbery WR, Landfield PW (2004) Incipient Alzheimer's disease: microarray correlation analyses reveal major transcriptional and tumor suppressor responses. Proc Natl Acad Sci USA 101:2173- 2178
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 2173-2178
-
-
Blalock, E.M.1
Geddes, J.W.2
Chen, K.C.3
Porter, N.M.4
Markesbery, W.R.5
Landfield, P.W.6
-
10
-
-
57049106701
-
Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD
-
Borg J, Chereul E (2008) Differential MRI patterns of brain atrophy in double or single transgenic mice for APP and/or SOD. J Neurosci Res 86:3275-3284
-
(2008)
J Neurosci Res
, vol.86
, pp. 3275-3284
-
-
Borg, J.1
Chereul, E.2
-
11
-
-
0032476137
-
Growth inhibitory factor and zinc affect neural cell cultures in a tissue specific manner
-
Bruinink A, Faller P, Sidler C, Bogumil R, Vasa'k M (1998) Growth inhibitory factor and zinc affect neural cell cultures in a tissue specific manner. Chem Biol Interact 115:167-174
-
(1998)
Chem Biol Interact
, vol.115
, pp. 167-174
-
-
Bruinink, A.1
Faller, P.2
Sidler, C.3
Bogumil Vasa'K, R.M.4
-
12
-
-
46749100924
-
Therapeutics for Alzheimer's disease based on the metal hypothesis
-
Bush AI, Tanzi RE (2008) Therapeutics for Alzheimer's disease based on the metal hypothesis. Neurotherapeutics 5:421-432
-
(2008)
Neurotherapeutics
, vol.5
, pp. 421-432
-
-
Bush, A.I.1
Tanzi, R.E.2
-
13
-
-
0035102386
-
Augmented senile plaque load in aged female betaamyloid precursor protein-transgenic mice
-
Callahan MJ, Lipinski WJ, Bian F, Durham RA, Pack A, Walker LC (2001) Augmented senile plaque load in aged female betaamyloid precursor protein-transgenic mice. Am J Pathol 158:1173-1177
-
(2001)
Am J Pathol
, vol.158
, pp. 1173-1177
-
-
Callahan, M.J.1
Lipinski, W.J.2
Bian, F.3
Durham, R.A.4
Pack, A.5
Walker, L.C.6
-
14
-
-
9844255568
-
Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice
-
Carlson GA, Borchelt DR, Dake A, Turner S, Danielson V, Coffin JD, Eckman C, Meiners J, Nilsen SP, Younkin SG, Hsiao KK (1997) Genetic modification of the phenotypes produced by amyloid precursor protein overexpression in transgenic mice. Hum Mol Genet 6:1951-1959
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1951-1959
-
-
Carlson, G.A.1
Borchelt, D.R.2
Dake, A.3
Turner, S.4
Danielson, V.5
Coffin, J.D.6
Eckman, C.7
Meiners, J.8
Nilsen, S.P.9
Younkin, S.G.10
Hsiao, K.K.11
-
15
-
-
33751546646
-
Metallothionein-I and -III expression in animal models of Alzheimer disease
-
Carrasco J, Adlard P, Cotman C, Quintana A, Penkowa M, Xu F, Van Nostrand WE, Hidalgo J (2006) Metallothionein-I and -III expression in animal models of Alzheimer disease. Neuroscience 143:911-922
-
(2006)
Neuroscience
, vol.143
, pp. 911-922
-
-
Carrasco, J.1
Adlard, P.2
Cotman, C.3
Quintana, A.4
Penkowa, M.5
Xu, F.6
Van Nostrand, W.E.7
Hidalgo, J.8
-
16
-
-
0032747632
-
Metallothionein (MT)-III: Generation of polyclonal antibodies, comparison with MT-I ? II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains
-
Carrasco J, Giralt M, Molinero A, Penkowa M, Moos T, Hidalgo J (1999) Metallothionein (MT)-III: generation of polyclonal antibodies, comparison with MT-I ? II in the freeze lesioned rat brain and in a bioassay with astrocytes, and analysis of Alzheimer's disease brains. J Neurotrauma 16:1115-1129
-
(1999)
J Neurotrauma
, vol.16
, pp. 1115-1129
-
-
Carrasco, J.1
Giralt, M.2
Molinero, A.3
Penkowa, M.4
Moos, T.5
Hidalgo, J.6
-
17
-
-
0038399723
-
Role of metallothionein- III following central nervous system damage
-
Carrasco J, Penkowa M, Giralt M, Camats J, Molinero A, Campbell IL, Palmiter RD, Hidalgo J (2003) Role of metallothionein- III following central nervous system damage. Neurobiol Dis 13:22-36
-
(2003)
Neurobiol Dis
, vol.13
, pp. 22-36
-
-
Carrasco, J.1
Penkowa, M.2
Giralt, M.3
Camats, J.4
Molinero, A.5
Campbell, I.L.6
Palmiter, R.D.7
Hidalgo, J.8
-
18
-
-
36849045250
-
Progesterone and estrogen regulate Alzheimer- like neuropathology in female 3xTg-AD mice
-
Carroll JC, Rosario ER, Chang L, Stanczyk FZ, Oddo S, LaFerla FM, Pike CJ (2007) Progesterone and estrogen regulate Alzheimer- like neuropathology in female 3xTg-AD mice. J Neurosci 27:13357-13365
-
(2007)
J Neurosci
, vol.27
, pp. 13357-13365
-
-
Carroll, J.C.1
Rosario, E.R.2
Chang, L.3
Stanczyk, F.Z.4
Oddo, S.5
Laferla, F.M.6
Pike, C.J.7
-
19
-
-
0038385516
-
Role of metallothioneins in peripheral nerve function and regeneration
-
Ceballos D, Lago N, Verdu E, Penkowa M, Carrasco J, Navarro X, Palmiter RD, Hidalgo J (2003) Role of metallothioneins in peripheral nerve function and regeneration. Cell Mol Life Sci 60:1209-1216
-
(2003)
Cell Mol Life Sci
, vol.60
, pp. 1209-1216
-
-
Ceballos, D.1
Lago, N.2
Verdu, E.3
Penkowa, M.4
Carrasco, J.5
Navarro, X.6
Palmiter, R.D.7
Hidalgo, J.8
-
20
-
-
34548738209
-
Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice
-
Clinton LK, Billings LM, Green KN, Caccamo A, Ngo J, Oddo S, McGaugh JL, LaFerla FM (2007) Age-dependent sexual dimorphism in cognition and stress response in the 3xTg-AD mice. Neurobiol Dis 28:76-82
-
(2007)
Neurobiol Dis
, vol.28
, pp. 76-82
-
-
Clinton, L.K.1
Billings, L.M.2
Green, K.N.3
Caccamo, A.4
Ngo, J.5
Oddo, S.6
McGaugh, J.L.7
Laferla, F.M.8
-
21
-
-
0037010289
-
Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: Transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and proinflammatory signaling
-
Colangelo V, Schurr J, Ball MJ, Pelaez RP, Bazan NG, Lukiw WJ (2002) Gene expression profiling of 12633 genes in Alzheimer hippocampal CA1: transcription and neurotrophic factor down-regulation and up-regulation of apoptotic and proinflammatory signaling. J Neurosci Res 70:462-473
-
(2002)
J Neurosci Res
, vol.70
, pp. 462-473
-
-
Colangelo, V.1
Schurr, J.2
Ball, M.J.3
Pelaez, R.P.4
Bazan, N.G.5
Lukiw, W.J.6
-
22
-
-
0033977114
-
Seizures and neuronal damage in mice lacking vesicular zinc
-
Cole TB, Robbins CA, Wenzel HJ, Schwartzkroin PA, Palmiter RD (2000) Seizures and neuronal damage in mice lacking vesicular zinc. Epilepsy Res 39:153-169
-
(2000)
Epilepsy Res
, vol.39
, pp. 153-169
-
-
Cole, T.B.1
Robbins, C.A.2
Wenzel, H.J.3
Schwartzkroin, P.A.4
Palmiter, R.D.5
-
23
-
-
0035191940
-
Expression and regulation of metallothioneins in the rat epididymis
-
Cyr DG, Dufresne J, Pillet S, Alfieri TJ, Hermo L (2001) Expression and regulation of metallothioneins in the rat epididymis. J Androl 22:124-135
-
(2001)
J Androl
, vol.22
, pp. 124-135
-
-
Cyr, D.G.1
Dufresne, J.2
Pillet, S.3
Alfieri, T.J.4
Hermo, L.5
-
24
-
-
0033360356
-
Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice
-
Chapman PF, White GL, Jones MW, Cooper-Blacketer D, Marshall VJ, Irizarry M, Younkin L, Good MA, Bliss TV, Hyman BT, Younkin SG, Hsiao KK (1999) Impaired synaptic plasticity and learning in aged amyloid precursor protein transgenic mice. Nat Neurosci 2:271-276
-
(1999)
Nat Neurosci
, vol.2
, pp. 271-276
-
-
Chapman, P.F.1
White, G.L.2
Jones, M.W.3
Cooper-Blacketer, D.4
Marshall, V.J.5
Irizarry, M.6
Younkin, L.7
Good, M.A.8
Bliss, T.V.9
Hyman, B.T.10
Younkin, S.G.11
Hsiao, K.K.12
-
25
-
-
77957774530
-
The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons
-
Chung RS, Howells C, Eaton ED, Shabala L, Zovo K, Palumaa P, Sillard R, Woodhouse A, Bennett WR, Ray S, Vickers JC, West AK (2010) The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons. PLoS ONE 5:e12030
-
(2010)
PLoS ONE
, vol.5
-
-
Chung, R.S.1
Howells, C.2
Eaton, E.D.3
Shabala, L.4
Zovo, K.5
Palumaa, P.6
Sillard, R.7
Woodhouse, A.8
Bennett, W.R.9
Ray, S.10
Vickers, J.C.11
West, A.K.12
-
26
-
-
0036445576
-
Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting
-
Chung RS, Vickers JC, Chuah MI, Eckhardt BL, West AK (2002) Metallothionein-III inhibits initial neurite formation in developing neurons as well as postinjury, regenerative neurite sprouting. Exp Neurol 178:1-12
-
(2002)
Exp Neurol
, vol.178
, pp. 1-12
-
-
Chung, R.S.1
Vickers, J.C.2
Chuah, M.I.3
Eckhardt, B.L.4
West, A.K.5
-
27
-
-
77951060145
-
Proteases and proteolysis in Alzheimer disease: A multifactorial view on the disease process
-
De Strooper B (2010) Proteases and proteolysis in Alzheimer disease: a multifactorial view on the disease process. Physiol Rev 90:465-494
-
(2010)
Physiol Rev
, vol.90
, pp. 465-494
-
-
De Strooper, B.1
-
28
-
-
33645816954
-
Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease
-
Dickstein DL, Biron KE, Ujiie M, Pfeifer CG, Jeffries AR, Jefferies WA (2006) Abeta peptide immunization restores blood-brain barrier integrity in Alzheimer disease. FASEB J 20:426-433
-
(2006)
FASEB J
, vol.20
, pp. 426-433
-
-
Dickstein, D.L.1
Biron, K.E.2
Ujiie, M.3
Pfeifer, C.G.4
Jeffries, A.R.5
Jefferies, W.A.6
-
29
-
-
0346106076
-
Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence
-
Dong J, Atwood CS, Anderson VE, Siedlak SL, Smith MA, Perry G, Carey PR (2003) Metal binding and oxidation of amyloid-beta within isolated senile plaque cores: Raman microscopic evidence. Biochemistry 42:2768-2773
-
(2003)
Biochemistry
, vol.42
, pp. 2768-2773
-
-
Dong, J.1
Atwood, C.S.2
Anderson, V.E.3
Siedlak, S.L.4
Smith, M.A.5
Perry, G.6
Carey, P.R.7
-
30
-
-
78149244116
-
Zinc release of Zn7-metallothionein-3 induces fibrillar type amyloidb aggregates
-
Durand J, Meloni G, Talmard C, Vasa'k M, Faller P (2010) Zinc release of Zn7-metallothionein-3 induces fibrillar type amyloidb aggregates. Metallomics 2:741-744
-
(2010)
Metallomics
, vol.2
, pp. 741-744
-
-
Durand, J.1
Meloni, G.2
Talmard, C.3
Vasa'K, M.4
Faller, P.5
-
31
-
-
33749604240
-
Metallothionein-3 is a component of a multiprotein complex in the mouse brain
-
El Ghazi I, Martin BL, Armitage IM (2006) Metallothionein-3 is a component of a multiprotein complex in the mouse brain. Exp Biol Med (Maywood) 231:1500-1506
-
(2006)
Exp Biol Med (Maywood
, vol.231
, pp. 1500-1506
-
-
El Ghazi, I.1
Martin, B.L.2
Armitage, I.M.3
-
32
-
-
79952133575
-
New proteins found interacting with brain metallothionein-3 are linked to secretion
-
El Ghazi I, Martin BL, Armitage IM (2010) New proteins found interacting with brain metallothionein-3 are linked to secretion. Int J Alzheimers Dis 2011:208634
-
(2010)
Int J Alzheimers Dis
, vol.2011
, pp. 208634
-
-
El Ghazi, I.1
Martin, B.L.2
Armitage, I.M.3
-
33
-
-
34147115541
-
Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease
-
El Khoury J, Toft M, Hickman SE, Means TK, Terada K, Geula C, Luster AD (2007) Ccr2 deficiency impairs microglial accumulation and accelerates progression of Alzheimer-like disease. Nat Med 13:432-438
-
(2007)
Nat Med
, vol.13
, pp. 432-438
-
-
El Khoury, J.1
Toft, M.2
Hickman, S.E.3
Means, T.K.4
Terada, K.5
Geula, C.6
Luster, A.D.7
-
34
-
-
0031016825
-
Disruption of the metallothionein-III gene in mice: Analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures
-
Erickson JC, Hollopeter G, Thomas SA, Froelick GJ, Palmiter RD (1997) Disruption of the metallothionein-III gene in mice: analysis of brain zinc, behavior, and neuron vulnerability to metals, aging, and seizures. J Neurosci 17:1271-1281
-
(1997)
J Neurosci
, vol.17
, pp. 1271-1281
-
-
Erickson, J.C.1
Hollopeter, G.2
Thomas, S.A.3
Froelick, G.J.4
Palmiter, R.D.5
-
35
-
-
0029044549
-
Expression of human metallothionein-III in transgenic mice
-
Erickson JC, Masters BA, Kelly EJ, Brinster RL, Palmiter RD (1995) Expression of human metallothionein-III in transgenic mice. Neurochem Int 27:35-41
-
(1995)
Neurochem Int
, vol.27
, pp. 35-41
-
-
Erickson, J.C.1
Masters, B.A.2
Kelly, E.J.3
Brinster, R.L.4
Palmiter, R.D.5
-
36
-
-
0028263925
-
Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein- III (GIF
-
Erickson JC, Sewell AK, Jensen LT, Winge DR, Palmiter RD (1994) Enhanced neurotrophic activity in Alzheimer's disease cortex is not associated with down-regulation of metallothionein- III (GIF). Brain Res 649:297-304
-
(1994)
Brain Res
, vol.649
, pp. 297-304
-
-
Erickson, J.C.1
Sewell, A.K.2
Jensen, L.T.3
Winge, D.R.4
Palmiter, R.D.5
-
37
-
-
0033520117
-
Evidence for a dynamic structure of human neuronal growth inhibitory factor and for major rearrangements of its metal- thiolate clusters
-
Faller P, Hasler DW, Zerbe O, Klauser S, Winge DR, Vasa'k M (1999) Evidence for a dynamic structure of human neuronal growth inhibitory factor and for major rearrangements of its metal- thiolate clusters. Biochemistry 38:10158-10167
-
(1999)
Biochemistry
, vol.38
, pp. 10158-10167
-
-
Faller, P.1
Hasler, D.W.2
Zerbe, O.3
Klauser, S.4
Winge, D.R.5
Vasa'K, M.6
-
38
-
-
0344972648
-
Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety
-
Fernandes C, Gonza'lez MI, Wilson CA, File SE (1999) Factor analysis shows that female rat behaviour is characterized primarily by activity, male rats are driven by sex and anxiety. Pharmacol Biochem Behav 64:731-738
-
(1999)
Pharmacol Biochem Behav
, vol.64
, pp. 731-738
-
-
Fernandes, C.1
Gonza'Lez, M.I.2
Wilson, C.A.3
File, S.E.4
-
39
-
-
0028344756
-
Interleukin-6 secretion from human astrocytoma cells induced by substance P
-
Gitter BD, Regoli D, Howbert JJ, Glasebrook AL, Waters DC (1994) Interleukin-6 secretion from human astrocytoma cells induced by substance P. J Neuroimmunol 51:101-108
-
(1994)
J Neuroimmunol
, vol.51
, pp. 101-108
-
-
Gitter, B.D.1
Regoli, D.2
Howbert, J.J.3
Glasebrook, A.L.4
Waters, D.C.5
-
40
-
-
84899547370
-
Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors
-
Guglielmotto M, Giliberto L, Tamagno E, Tabaton M (2010) Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors. Front Aging Neurosci 2:3
-
(2010)
Front Aging Neurosci
, vol.2
, pp. 3
-
-
Guglielmotto, M.1
Giliberto, L.2
Tamagno, E.3
Tabaton, M.4
-
41
-
-
0034727640
-
Effect of the two conserved prolines of human growth inhibitory factor (metallothionein-3) on its biological activity and structure fluctuation: Comparison with a mutant protein
-
Hasler DW, Jensen LT, Zerbe O, Winge DR, Vasa'k M (2000) Effect of the two conserved prolines of human growth inhibitory factor (metallothionein-3) on its biological activity and structure fluctuation: comparison with a mutant protein. Biochemistry 39:14567-14575
-
(2000)
Biochemistry
, vol.39
, pp. 14567-14575
-
-
Hasler, D.W.1
Jensen, L.T.2
Zerbe, O.3
Winge, D.R.4
Vasa'K, M.5
-
43
-
-
33749620702
-
Expression of metallothionein-I, -II, and -III in Alzheimer disease and animal models of neuroinflammation
-
Hidalgo J, Penkowa M, Espejo C, Marti Nez-Ca Ceres EM, Carrasco J, Quintana A, Molinero A, Florit S, Giralt M, Ortega- Aznar A (2006) Expression of metallothionein-I, -II, and -III in Alzheimer disease and animal models of neuroinflammation. Exp Biol Med (Maywood) 231:1450-1458
-
(2006)
Exp Biol Med (Maywood)
, vol.231
, pp. 1450-1458
-
-
Hidalgo, J.1
Penkowa, M.2
Espejo, C.3
Marti Nez-Ca Ceres, E.M.4
Carrasco, J.5
Quintana, A.6
Molinero, A.7
Florit, S.8
Giralt, M.9
Ortega- Aznar, A.10
-
44
-
-
0031914718
-
Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes
-
Holcomb L, Gordon MN, McGowan E, Yu X, Benkovic S, Jantzen P, Wright K, Saad I, Mueller R, Morgan D, Sanders S, Zehr C, O'Campo K, Hardy J, Prada CM, Eckman C, Younkin S, Hsiao K, Duff K (1998) Accelerated Alzheimer-type phenotype in transgenic mice carrying both mutant amyloid precursor protein and presenilin 1 transgenes. Nat Med 4:97-100
-
(1998)
Nat Med
, vol.4
, pp. 97-100
-
-
Holcomb, L.1
Gordon, M.N.2
McGowan, E.3
Yu, X.4
Benkovic, S.5
Jantzen, P.6
Wright, K.7
Saad, I.8
Mueller, R.9
Morgan, D.10
Sanders, S.11
Zehr, C.12
O'Campo, K.13
Hardy, J.14
Prada, C.M.15
Eckman, C.16
Younkin, S.17
Hsiao, K.18
Duff, K.19
-
45
-
-
0032756213
-
Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: Lack of association with amyloid deposits
-
Holcomb LA, Gordon MN, Jantzen P, Hsiao K, Duff K, Morgan D (1999) Behavioral changes in transgenic mice expressing both amyloid precursor protein and presenilin-1 mutations: lack of association with amyloid deposits. Behav Genet 29:177-185
-
(1999)
Behav Genet
, vol.29
, pp. 177-185
-
-
Holcomb, L.A.1
Gordon, M.N.2
Jantzen, P.3
Hsiao, K.4
Duff, K.5
Morgan, D.6
-
46
-
-
32244434439
-
Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain
-
Hozumi I, Uchida Y, Watabe K, Sakamoto T, Inuzuka T (2006) Growth inhibitory factor (GIF) can protect from brain damage due to stab wounds in rat brain. Neurosci Lett 395:220-223
-
(2006)
Neurosci Lett
, vol.395
, pp. 220-223
-
-
Hozumi, I.1
Uchida, Y.2
Watabe, K.3
Sakamoto, T.4
Inuzuka, T.5
-
47
-
-
0029742199
-
Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice
-
Hsiao K, Chapman P, Nilsen S, Eckman C, Harigaya Y, Younkin S, Yang F, Cole G (1996) Correlative memory deficits, Abeta elevation, and amyloid plaques in transgenic mice. Science 274:99-102
-
(1996)
Science
, vol.274
, pp. 99-102
-
-
Hsiao, K.1
Chapman, P.2
Nilsen, S.3
Eckman, C.4
Harigaya, Y.5
Younkin, S.6
Yang, F.7
Cole, G.8
-
48
-
-
80052779276
-
Toxicity of Alzheimer's disease-associated Ab peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability
-
Hua H, Mu;nter L, Harmeier A, Georgiev O, Multhaup G, Schaffner W (2011) Toxicity of Alzheimer's disease-associated Ab peptide is ameliorated in a Drosophila model by tight control of zinc and copper availability. Biol Chem 392:919-926
-
(2011)
Biol Chem
, vol.392
, pp. 919-926
-
-
Hua, H.1
Münter, L.2
Harmeier, A.3
Georgiev, O.4
Multhaup, G.5
Schaffner, W.6
-
49
-
-
0033363939
-
SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein
-
Iadecola C, Zhang F, Niwa K, Eckman C, Turner SK, Fischer E, Younkin S, Borchelt DR, Hsiao KK, Carlson GA (1999) SOD1 rescues cerebral endothelial dysfunction in mice overexpressing amyloid precursor protein. Nat Neurosci 2:157-161
-
(1999)
Nat Neurosci
, vol.2
, pp. 157-161
-
-
Iadecola, C.1
Zhang, F.2
Niwa, K.3
Eckman, C.4
Turner, S.K.5
Fischer, E.6
Younkin, S.7
Borchelt, D.R.8
Hsiao, K.K.9
Carlson, G.A.10
-
50
-
-
80455125998
-
Castration- and aging-induced changes in the expression of zinc transporter and metallothionein in rat prostate
-
Iguchi K, Morihara N, Usui S, Hayama M, Sugimura Y, Hirano K (2011) Castration- and aging-induced changes in the expression of zinc transporter and metallothionein in rat prostate. J Androl 32:144-150
-
(2011)
J Androl
, vol.32
, pp. 144-150
-
-
Iguchi, K.1
Morihara, N.2
Usui, S.3
Hayama, M.4
Sugimura, Y.5
Hirano, K.6
-
51
-
-
0034811882
-
Metallothionein-III antagonizes the neurotoxic and neurotrophic effects of amyloid beta peptides
-
Irie Y, Keung WM (2001) Metallothionein-III antagonizes the neurotoxic and neurotrophic effects of amyloid beta peptides. Biochem Biophys Res Commun 282:416-420
-
(2001)
Biochem Biophys Res Commun
, vol.282
, pp. 416-420
-
-
Irie, Y.1
Keung, W.M.2
-
52
-
-
0037449446
-
Anti-amyloid beta activity of metallothionein-III is different from its neuronal growth inhibitory activity: Structure-activity studies
-
Irie Y, Keung WM (2003) Anti-amyloid beta activity of metallothionein-III is different from its neuronal growth inhibitory activity: structure-activity studies. Brain Res 960:228-234
-
(2003)
Brain Res
, vol.960
, pp. 228-234
-
-
Irie, Y.1
Keung, W.M.2
-
53
-
-
78751644048
-
Amyloid-b and tau-A toxic pas de deux in Alzheimer's disease
-
Ittner LM, Go;tz J (2011) Amyloid-b and tau - a toxic pas de deux in Alzheimer's disease. Nat Rev Neurosci 12:65-72
-
(2011)
Nat Rev Neurosci
, vol.12
, pp. 65-72
-
-
Ittner, L.M.1
Götz, J.2
-
54
-
-
0037088956
-
Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months
-
King DL, Arendash GW (2002) Behavioral characterization of the Tg2576 transgenic model of Alzheimer's disease through 19 months. Physiol Behav 75:627-642
-
(2002)
Physiol Behav
, vol.75
, pp. 627-642
-
-
King, D.L.1
Arendash, G.W.2
-
55
-
-
0033199822
-
Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease
-
King DL, Arendash GW, Crawford F, Sterk T, Menendez J, Mullan MJ (1999) Progressive and gender-dependent cognitive impairment in the APP(SW) transgenic mouse model for Alzheimer's disease. Behav Brain Res 103:145-162
-
(1999)
Behav Brain Res
, vol.103
, pp. 145-162
-
-
King, D.L.1
Arendash, G.W.2
Crawford, F.3
Sterk, T.4
Menendez, J.5
Mullan, M.J.6
-
56
-
-
14644397252
-
Zn7metallothionein-3 and the synaptic vesicle cycle: Interaction of metallothionein-3 with the small GTPase Rab3A
-
Knipp M, Meloni G, Roschitzki B, Vasa'k M (2005) Zn7metallothionein-3 and the synaptic vesicle cycle: interaction of metallothionein-3 with the small GTPase Rab3A. Biochemistry 44:3159-3165
-
(2005)
Biochemistry
, vol.44
, pp. 3159-3165
-
-
Knipp, M.1
Meloni, G.2
Roschitzki, B.3
Vasa'K, M.4
-
57
-
-
70350303312
-
Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors
-
Koumura A, Kakefuda K, Honda A, Ito Y, Tsuruma K, Shimazawa M, Uchida Y, Hozumi I, Satoh M, Inuzuka T, Hara H (2009) Metallothionein-3 deficient mice exhibit abnormalities of psychological behaviors. Neurosci Lett 467:11-14
-
(2009)
Neurosci Lett
, vol.467
, pp. 11-14
-
-
Koumura, A.1
Kakefuda, K.2
Honda, A.3
Ito, Y.4
Tsuruma, K.5
Shimazawa, M.6
Uchida, Y.7
Hozumi, I.8
Satoh, M.9
Inuzuka, T.10
Hara, H.11
-
58
-
-
25144503548
-
Densecore plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls
-
Kumar-Singh S, Pirici D, McGowan E, Serneels S, Ceuterick C, Hardy J, Duff K, Dickson D, Van Broeckhoven C (2005) Densecore plaques in Tg2576 and PSAPP mouse models of Alzheimer's disease are centered on vessel walls. Am J Pathol 167:527-543
-
(2005)
Am J Pathol
, vol.167
, pp. 527-543
-
-
Kumar-Singh, S.1
Pirici, D.2
McGowan, E.3
Serneels, S.4
Ceuterick, C.5
Hardy, J.6
Duff, K.7
Dickson, D.8
Van Broeckhoven, C.9
-
59
-
-
17744380813
-
Identification of mouse brain proteins associated with isoform 3 of metallothionein
-
Lahti DW, Hoekman JD, Tokheim AM, Martin BL, Armitage IM (2005) Identification of mouse brain proteins associated with isoform 3 of metallothionein. Protein Sci 14:1151-1157
-
(2005)
Protein Sci
, vol.14
, pp. 1151-1157
-
-
Lahti, D.W.1
Hoekman, J.D.2
Tokheim, A.M.3
Martin, B.L.4
Armitage, I.M.5
-
60
-
-
0037159635
-
Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation
-
Lalonde R, Dumont M, Staufenbiel M, Sturchler-Pierrat C, Strazielle C (2002) Spatial learning, exploration, anxiety, and motor coordination in female APP23 transgenic mice with the Swedish mutation. Brain Res 956:36-44
-
(2002)
Brain Res
, vol.956
, pp. 36-44
-
-
Lalonde, R.1
Dumont, M.2
Staufenbiel, M.3
Sturchler-Pierrat, C.4
Strazielle, C.5
-
61
-
-
0038022595
-
Transgenic mice expressing the betaAPP695SWE mutation: Effects on exploratory activity, anxiety, and motor coordination
-
Lalonde R, Lewis TL, Strazielle C, Kim H, Fukuchi K (2003) Transgenic mice expressing the betaAPP695SWE mutation: effects on exploratory activity, anxiety, and motor coordination. Brain Res 977:38-45
-
(2003)
Brain Res
, vol.977
, pp. 38-45
-
-
Lalonde, R.1
Lewis, T.L.2
Strazielle, C.3
Kim, H.4
Fukuchi, K.5
-
62
-
-
0037188530
-
Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice
-
Lee JY, Cole TB, Palmiter RD, Suh SW, Koh JY (2002) Contribution by synaptic zinc to the gender-disparate plaque formation in human Swedish mutant APP transgenic mice. Proc Natl Acad Sci USA 99:7705-7710
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 7705-7710
-
-
Lee, J.Y.1
Cole, T.B.2
Palmiter, R.D.3
Suh, S.W.4
Koh, J.Y.5
-
63
-
-
0033139740
-
Histochemically reactive zinc in plaques of the Swedish mutant beta-amyloid precursor protein transgenic mice
-
Lee JY, Mook-Jung I, Koh JY (1999) Histochemically reactive zinc in plaques of the Swedish mutant beta-amyloid precursor protein transgenic mice. J Neurosci 19:RC10:1-5
-
(1999)
J Neurosci
, vol.19
, Issue.RC10
, pp. 1-5
-
-
Lee, J.Y.1
Mook-Jung, I.2
Koh, J.Y.3
-
64
-
-
33645038471
-
A specific amyloid-beta protein assembly in the brain impairs memory
-
Lesné S, Koh MT, Kotilinek L, Kayed R, Glabe CG, Yang A, Gallagher M, Ashe KH (2006) A specific amyloid-beta protein assembly in the brain impairs memory. Nature 440:352-357
-
(2006)
Nature
, vol.440
, pp. 352-357
-
-
Lesné, S.1
Koh, M.T.2
Kotilinek, L.3
Kayed, R.4
Glabe, C.G.5
Yang, A.6
Gallagher, M.7
Ashe, K.H.8
-
65
-
-
43049124437
-
Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: A reference data set
-
Liang WS, Dunckley T, Beach TG, Grover A, Mastroeni D, Ramsey K, Caselli RJ, Kukull WA, McKeel D, Morris JC, Hulette CM, Schmechel D, Reiman EM, Rogers J, Stephan DA (2008) Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set. Physiol Genomics 33:240-256
-
(2008)
Physiol Genomics
, vol.33
, pp. 240-256
-
-
Liang, W.S.1
Dunckley, T.2
Beach, T.G.3
Grover, A.4
Mastroeni, D.5
Ramsey, K.6
Caselli, R.J.7
Kukull, W.A.8
McKeel, D.9
Morris, J.C.10
Hulette, C.M.11
Schmechel, D.12
Reiman, E.M.13
Rogers, J.14
Stephan, D.A.15
-
66
-
-
80755140083
-
Metallothionein and brain inflammation
-
Manso Y, Adlard PA, Carrasco J, Vasa'k M, Hidalgo J (2011) Metallothionein and brain inflammation. J Biol Inorg Chem 16:1103-1113
-
(2011)
J Biol Inorg Chem
, vol.16
, pp. 1103-1113
-
-
Manso, Y.1
Adlard, P.A.2
Carrasco, J.3
Vasa'K, M.4
Hidalgo, J.5
-
67
-
-
69449096141
-
Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease
-
Massaad CA, Washington TM, Pautler RG, Klann E (2009) Overexpression of SOD-2 reduces hippocampal superoxide and prevents memory deficits in a mouse model of Alzheimer's disease. Proc Natl Acad Sci USA 106:13576-13581
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 13576-13581
-
-
Massaad, C.A.1
Washington, T.M.2
Pautler, R.G.3
Klann, E.4
-
68
-
-
0027994282
-
Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles
-
Masters BA, Quaife CJ, Erickson JC, Kelly EJ, Froelick GJ, Zambrowicz BP, Brinster RL, Palmiter RD (1994) Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles. J Neurosci 14:5844-5857
-
(1994)
J Neurosci
, vol.14
, pp. 5844-5857
-
-
Masters, B.A.1
Quaife, C.J.2
Erickson, J.C.3
Kelly, E.J.4
Froelick, G.J.5
Zambrowicz, B.P.6
Brinster, R.L.7
Palmiter, R.D.8
-
69
-
-
33646145729
-
Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: Implications for Alzheimer beta-amyloid pathology
-
Maynard CJ, Cappai R, Volitakis I, Cherny RA, Masters CL, Li QX, Bush AI (2006) Gender and genetic background effects on brain metal levels in APP transgenic and normal mice: implications for Alzheimer beta-amyloid pathology. J Inorg Biochem 100:952-962
-
(2006)
J Inorg Biochem
, vol.100
, pp. 952-962
-
-
Maynard, C.J.1
Cappai, R.2
Volitakis, I.3
Cherny, R.A.4
Masters, C.L.5
Li, Q.X.6
Bush, A.I.7
-
70
-
-
0037160028
-
Overexpression of Alzheimer's disease amyloid-beta opposes the agedependent elevations of brain copper and iron
-
Maynard CJ, Cappai R, Volitakis I, Cherny RA, White AR, Beyreuther K, Masters CL, Bush AI, Li QX (2002) Overexpression of Alzheimer's disease amyloid-beta opposes the agedependent elevations of brain copper and iron. J Biol Chem 277:44670-44676
-
(2002)
J Biol Chem
, vol.277
, pp. 44670-44676
-
-
Maynard, C.J.1
Cappai, R.2
Volitakis, I.3
Cherny, R.A.4
White, A.R.5
Beyreuther, K.6
Masters, C.L.7
Bush, A.I.8
Li, Q.X.9
-
71
-
-
60849097262
-
Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice
-
Meilandt WJ, Cisse M, Ho K, Wu T, Esposito LA, Scearce- Levie K, Cheng IH, Yu GQ, Mucke L (2009) Neprilysin overexpression inhibits plaque formation but fails to reduce pathogenic Abeta oligomers and associated cognitive deficits in human amyloid precursor protein transgenic mice. J Neurosci Res 29:1977-1986
-
(2009)
J Neurosci Res
, vol.29
, pp. 1977-1986
-
-
Meilandt, W.J.1
Cisse, M.2
Ho, K.3
Wu, T.4
Esposito, L.A.5
Scearce- Levie, K.6
Cheng, I.H.7
Yu, G.Q.8
Mucke, L.9
-
72
-
-
22544466415
-
Detection of neuronal growth inhibitory factor (metallothionein-3) in polyacrylamide gels and by Western blot analysis
-
Meloni G, Knipp M, Vasa'k M (2005) Detection of neuronal growth inhibitory factor (metallothionein-3) in polyacrylamide gels and by Western blot analysis. J Biochem Biophys Methods 64:76-81
-
(2005)
J Biochem Biophys Methods
, vol.64
, pp. 76-81
-
-
Meloni, G.1
Knipp, M.2
Vasa'K, M.3
-
73
-
-
43749104422
-
Metal swap between Zn7-metallothionein- 3 and amyloid-beta-Cu protects against amyloid-beta toxicity
-
Meloni G, Sonois V, Delaine T, Guilloreau L, Gillet A, Teissié J, Faller P, Vasa'k M (2008) Metal swap between Zn7-metallothionein- 3 and amyloid-beta-Cu protects against amyloid-beta toxicity. Nat Chem Biol 4:366-372
-
(2008)
Nat Chem Biol
, vol.4
, pp. 366-372
-
-
Meloni, G.1
Sonois, V.2
Delaine, T.3
Guilloreau, L.4
Gillet, A.5
Teissié, J.6
Faller, P.7
Vasa'K, M.8
-
74
-
-
79955630377
-
Redox activity of a-synuclein-Cu is silenced by Zn7-metallothionein-3
-
Meloni G, Vasa'k M (2011) Redox activity of a-synuclein-Cu is silenced by Zn7-metallothionein-3. Free Radic Biol Med 50:1471-1479
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 1471-1479
-
-
Meloni, G.1
Vasa'K, M.2
-
75
-
-
0031818254
-
Expression of the gene encoding metallothionein-3 in organs of the reproductive system
-
Moffatt P, Se'guin C (1998) Expression of the gene encoding metallothionein-3 in organs of the reproductive system. DNA Cell Biol 17:501-510
-
(1998)
DNA Cell Biol
, vol.17
, pp. 501-510
-
-
Moffatt, P.1
Se'Guin, C.2
-
76
-
-
0034047740
-
Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons
-
Montoliu C, Monfort P, Carrasco J, Palacios O, Capdevila M, Hidalgo J, Felipo V (2000) Metallothionein-III prevents glutamate and nitric oxide neurotoxicity in primary cultures of cerebellar neurons. J Neurochem 75:266-273
-
(2000)
J Neurochem
, vol.75
, pp. 266-273
-
-
Montoliu, C.1
Monfort, P.2
Carrasco, J.3
Palacios, O.4
Capdevila, M.5
Hidalgo, J.6
Felipo, V.7
-
77
-
-
34249860495
-
Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct
-
Necula M, Kayed R, Milton S, Glabe CG (2007) Small molecule inhibitors of aggregation indicate that amyloid beta oligomerization and fibrillization pathways are independent and distinct. J Biol Chem 282:10311-10324
-
(2007)
J Biol Chem
, vol.282
, pp. 10311-10324
-
-
Necula, M.1
Kayed, R.2
Milton, S.3
Glabe, C.G.4
-
78
-
-
13444304256
-
Metal binding of metallothionein-3 versus metallothionein-2: Lower affinity and higher plasticity
-
Palumaa P, Tammiste I, Kruusel K, Kangur L, Jornvall H, Sillard R (2005) Metal binding of metallothionein-3 versus metallothionein-2: lower affinity and higher plasticity. Biochim Biophys Acta 1747:205-211
-
(2005)
Biochim Biophys Acta
, vol.1747
, pp. 205-211
-
-
Palumaa, P.1
Tammiste, I.2
Kruusel, K.3
Kangur, L.4
Jornvall, H.5
Sillard, R.6
-
79
-
-
0019018003
-
Reactivity of the thiol group in human and bovine albumin at pH 3-9, as measured by exchange with 2,20-dithiodipyridine
-
Pedersen AO, Jacobsen J (1980) Reactivity of the thiol group in human and bovine albumin at pH 3-9, as measured by exchange with 2,20-dithiodipyridine. Eur J Biochem 106:291-295
-
(1980)
Eur J Biochem
, vol.106
, pp. 291-295
-
-
Pedersen, A.O.1
Jacobsen, J.2
-
80
-
-
84857612193
-
Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-b peptide promotes amyloid- related structural changes
-
Pedersen JT, Hureau C, Hemmingsen L, Heegaard NH, Ostergaard J, VasákM, Faller P (2012) Rapid exchange of metal between Zn(7)-metallothionein-3 and amyloid-b peptide promotes amyloid- related structural changes. Biochem 51:1697-1706
-
(2012)
Biochem
, vol.51
, pp. 1697-1706
-
-
Pedersen, J.T.1
Hureau, C.2
Hemmingsen, L.3
Heegaard, N.H.4
Ostergaard, J.5
Vasák, M.6
Faller, P.7
-
81
-
-
33645843958
-
Specificity and divergence in the neurobiological effects of different metallothioneins after brain injury
-
Penkowa M, Tió L, Giralt M, Quintana A, Molinero A, Atrian S, Vasa'k M, Hidalgo J (2006) Specificity and divergence in the neurobiological effects of different metallothioneins after brain injury. J Neurosci Res 83:974-984
-
(2006)
J Neurosci Res
, vol.83
, pp. 974-984
-
-
Penkowa, M.1
Tió, L.2
Giralt, M.3
Quintana, A.4
Molinero, A.5
Atrian, S.6
Vasa'K, M.7
Hidalgo, J.8
-
82
-
-
10744228112
-
In vivo reduction of amyloid-beta by a mutant copper transporter
-
Phinney AL, Drisaldi B, Schmidt SD, Lugowski S, Coronado V, Liang Y, Horne P, Yang J, Sekoulidis J, Coomaraswamy J, Chishti MA, Cox DW, Mathews PM, Nixon RA, Carlson GA, St George-Hyslop P, Westaway D (2003) In vivo reduction of amyloid-beta by a mutant copper transporter. Proc Natl Acad Sci USA 100:14193-14198
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 14193-14198
-
-
Phinney, A.L.1
Drisaldi, B.2
Schmidt, S.D.3
Lugowski, S.4
Coronado, V.5
Liang, Y.6
Horne, P.7
Yang, J.8
Sekoulidis, J.9
Coomaraswamy, J.10
Chishti, M.A.11
Cox, D.W.12
Mathews, P.M.13
Nixon, R.A.14
Carlson, G.A.15
St George-Hyslop, P.16
Westaway, D.17
-
83
-
-
75749142678
-
Heat shock but not cold shock leads to disturbed intracellular zinc homeostasis
-
Pirev E, Ince Y, Sies H, Kro;ncke KD (2010) Heat shock but not cold shock leads to disturbed intracellular zinc homeostasis. J Cell Physiol 223:103-109
-
(2010)
J Cell Physiol
, vol.223
, pp. 103-109
-
-
Pirev, E.1
Ince, Y.2
Sies, H.3
Kröncke, K.D.4
-
84
-
-
33846967462
-
Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease
-
Pugh PL, Richardson JC, Bate ST, Upton N, Sunter D (2007) Non-cognitive behaviours in an APP/PS1 transgenic model of Alzheimer's disease. Behav Brain Res 178:18-28
-
(2007)
Behav Brain Res
, vol.178
, pp. 18-28
-
-
Pugh, P.L.1
Richardson, J.C.2
Bate, S.T.3
Upton, N.4
Sunter, D.5
-
85
-
-
0037109771
-
Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins
-
Puttaparthi K, Gitomer WL, Krishnan U, Son M, Rajendran B, Elliott JL (2002) Disease progression in a transgenic model of familial amyotrophic lateral sclerosis is dependent on both neuronal and non-neuronal zinc binding proteins. J Neurosci 22:8790-8796
-
(2002)
J Neurosci
, vol.22
, pp. 8790-8796
-
-
Puttaparthi, K.1
Gitomer, W.L.2
Krishnan, U.3
Son, M.4
Rajendran, B.5
Elliott, J.L.6
-
86
-
-
0037020159
-
Engineering of metallothionein-3 neuroinhibitory activity into the inactive isoform metallothionein-1
-
Romero-Isart N, Jensen LT, Zerbe O, Winge DR, Vasa'k M (2002) Engineering of metallothionein-3 neuroinhibitory activity into the inactive isoform metallothionein-1. J Biol Chem 277:37023-37028
-
(2002)
J Biol Chem
, vol.277
, pp. 37023-37028
-
-
Romero-Isart, N.1
Jensen, L.T.2
Zerbe, O.3
Winge, D.R.4
Vasa'K, M.5
-
87
-
-
77957982982
-
Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways
-
Rosario ER, Carroll J, Pike CJ (2010) Testosterone regulation of Alzheimer-like neuropathology in male 3xTg-AD mice involves both estrogen and androgen pathways. Brain Res 1359:281-290
-
(2010)
Brain Res
, vol.1359
, pp. 281-290
-
-
Rosario, E.R.1
Carroll, J.2
Pike, C.J.3
-
88
-
-
33947383715
-
Copper and clioquinol treatment in young APP transgenic and wild-type mice: Effects on life expectancy, body weight, and metal-ion levels
-
Scha;fer S, Pajonk FG, Multhaup G, Bayer TA (2007) Copper and clioquinol treatment in young APP transgenic and wild-type mice: effects on life expectancy, body weight, and metal-ion levels. J Mol Med (Berl) 85:405-413
-
(2007)
J Mol Med (Berl)
, vol.85
, pp. 405-413
-
-
Schafer, S.1
Pajonk, F.G.2
Multhaup, G.3
Bayer, T.A.4
-
89
-
-
0028932454
-
Bioactivity of metallothionein-3 correlates with its novel beta domain sequence rather than metal binding properties
-
Sewell AK, Jensen LT, Erickson JC, Palmiter RD, Winge DR (1995) Bioactivity of metallothionein-3 correlates with its novel beta domain sequence rather than metal binding properties. Biochemistry 34:4740-4747
-
(1995)
Biochemistry
, vol.34
, pp. 4740-4747
-
-
Sewell, A.K.1
Jensen, L.T.2
Erickson, J.C.3
Palmiter, R.D.4
Winge, D.R.5
-
90
-
-
77956090035
-
Impact of gender differences on the outcome of Alzheimer's disease
-
Sinforiani E, Citterio A, Zucchella C, Bono G, Corbetta S, Merlo P, Mauri M (2010) Impact of gender differences on the outcome of Alzheimer's disease. Dement Geriatr Cogn Disord 30:147-154
-
(2010)
Dement Geriatr Cogn Disord
, vol.30
, pp. 147-154
-
-
Sinforiani, E.1
Citterio, A.2
Zucchella, C.3
Bono, G.4
Corbetta, S.5
Merlo, P.6
Mauri, M.7
-
91
-
-
0033986037
-
Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains
-
Suh SW, Jensen KB, Jensen MS, Silva DS, Kesslak PJ, Danscher G, Frederickson CJ (2000) Histochemically-reactive zinc in amyloid plaques, angiopathy, and degenerating neurons of Alzheimer's diseased brains. Brain Res 852:274-278
-
(2000)
Brain Res
, vol.852
, pp. 274-278
-
-
Suh, S.W.1
Jensen, K.B.2
Jensen, M.S.3
Silva, D.S.4
Kesslak, P.J.5
Danscher, G.6
Frederickson, C.J.7
-
92
-
-
75149118997
-
Role of oxidative stress in the progression of Alzheimer's disease
-
Sultana R, Butterfield DA (2010) Role of oxidative stress in the progression of Alzheimer's disease. J Alzheimers Dis 19:341-353
-
(2010)
J Alzheimers Dis
, vol.19
, pp. 341-353
-
-
Sultana, R.1
Butterfield, D.A.2
-
93
-
-
79952236194
-
Presenilin- 2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's disease
-
Toda T, Noda Y, Ito G, Maeda M, Shimizu T (2011) Presenilin- 2 mutation causes early amyloid accumulation and memory impairment in a transgenic mouse model of Alzheimer's disease. J Biomed Biotechnol 2011:617974
-
(2011)
J Biomed Biotechnol
, vol.2011
, pp. 617974
-
-
Toda, T.1
Noda, Y.2
Ito, G.3
Maeda, M.4
Shimizu, T.5
-
94
-
-
69949167074
-
Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators
-
Tougu V, Karafin A, Zovo K, Chung RS, Howells C, West AK, Palumaa P (2009) Zn(II)- and Cu(II)-induced non-fibrillar aggregates of amyloid-beta (1-42) peptide are transformed to amyloid fibrils, both spontaneously and under the influence of metal chelators. J Neurochem 110:1784-1795
-
(2009)
J Neurochem
, vol.110
, pp. 1784-1795
-
-
Tougu, V.1
Karafin, A.2
Zovo, K.3
Chung, R.S.4
Howells, C.5
West, A.K.6
Palumaa, P.7
-
95
-
-
0027048685
-
Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease
-
Tsuji S, Kobayashi H, Uchida Y, Ihara Y, Miyatake T (1992) Molecular cloning of human growth inhibitory factor cDNA and its down-regulation in Alzheimer's disease. EMBO J 11:4843-4850
-
(1992)
EMBO J
, vol.11
, pp. 4843-4850
-
-
Tsuji, S.1
Kobayashi, H.2
Uchida, Y.3
Ihara, Y.4
Miyatake, T.5
-
96
-
-
79251644774
-
Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease
-
Twine NA, Janitz K, Wilkins MR, Janitz M (2011) Whole transcriptome sequencing reveals gene expression and splicing differences in brain regions affected by Alzheimer's disease. PLoS ONE 6:e16266
-
(2011)
PLoS ONE
, vol.6
-
-
Twine, N.A.1
Janitz, K.2
Wilkins, M.R.3
Janitz, M.4
-
97
-
-
0037200013
-
Growth inhibitory factor prevents neurite extension and death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging
-
Uchida Y, Gomi F, Masumizu T, Miura Y (2002) Growth inhibitory factor prevents neurite extension and death of cortical neurons caused by high oxygen exposure through hydroxyl radical scavenging. J Biol Chem 277:32353-32359
-
(2002)
J Biol Chem
, vol.277
, pp. 32353-32359
-
-
Uchida, Y.1
Gomi, F.2
Masumizu, T.3
Miura, Y.4
-
98
-
-
0025768860
-
The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein
-
Uchida Y, Takio K, Titani K, Ihara Y, Tomonaga M (1991) The growth inhibitory factor that is deficient in the Alzheimer's disease brain is a 68 amino acid metallothionein-like protein. Neuron 7:337-347
-
(1991)
Neuron
, vol.7
, pp. 337-347
-
-
Uchida, Y.1
Takio, K.2
Titani, K.3
Ihara, Y.4
Tomonaga, M.5
-
99
-
-
0026318278
-
Metal removal and substitution in vertebrate and invertebrate metallothioneins
-
VasákM(1991) Metal removal and substitution in vertebrate and invertebrate metallothioneins. Methods Enzymol, 205:452-458
-
(1991)
Methods Enzymol
, vol.205
, pp. 452-458
-
-
Vasák, M.1
-
100
-
-
80755140125
-
Chemistry and biology of mammalian metallothioneins
-
Vasa'k M, Meloni G (2011) Chemistry and biology of mammalian metallothioneins. J Biol Inorg Chem 16:1067-1078
-
(2011)
J Biol Inorg Chem
, vol.16
, pp. 1067-1078
-
-
Vasak, M.1
Meloni, G.2
-
101
-
-
84872841524
-
Gender, sex steroid hormones, and Alzheimer's disease
-
in press doi:10.1016/ j.yhbeh.2012.04.006
-
Vest RS, Pike CJ (2012) Gender, sex steroid hormones, and Alzheimer's disease. Horm Behav (in press). doi:10.1016/ j.yhbeh.2012.04.006
-
(2012)
Horm Behav
-
-
Vest, R.S.1
Pike, C.J.2
-
102
-
-
0037285379
-
Preliminary studies on Alzheimer's disease using cDNA microarrays
-
Wang G, Zhang Y, Chen B, Cheng J (2003) Preliminary studies on Alzheimer's disease using cDNA microarrays. Mech Ageing Dev 124:115-124
-
(2003)
Mech Ageing Dev
, vol.124
, pp. 115-124
-
-
Wang, G.1
Zhang, Y.2
Chen, B.3
Cheng, J.4
-
103
-
-
44649152946
-
Metallothionein in the central nervous system: Roles in protection, regeneration and cognition
-
West AK, Hidalgo J, Eddins D, Levin ED, Aschner M (2008) Metallothionein in the central nervous system: Roles in protection, regeneration and cognition. Neurotoxicology 29:489-503
-
(2008)
Neurotoxicology
, vol.29
, pp. 489-503
-
-
West, A.K.1
Hidalgo, J.2
Eddins, D.3
Levin, E.D.4
Aschner, M.5
-
104
-
-
80755153034
-
Neuroprotection and regeneration by extracellular metallothionein via lipoproteinreceptor- related proteins
-
West AK, Leung JY, Chung RS (2011) Neuroprotection and regeneration by extracellular metallothionein via lipoproteinreceptor- related proteins. J Biol Inorg Chem, 16:1115-1122
-
J Biol Inorg Chem
, vol.2011
, Issue.16
, pp. 1115-1122
-
-
West, A.K.1
Leung, J.Y.2
Chung, R.S.3
-
105
-
-
0035831110
-
Metallothionein III is reduced in Alzheimer's disease
-
Yu WH, Lukiw WJ, Bergeron C, Niznik HB, Fraser PE (2001) Metallothionein III is reduced in Alzheimer's disease. Brain Res 894:37-45
-
(2001)
Brain Res
, vol.894
, pp. 37-45
-
-
Yu, W.H.1
Lukiw, W.J.2
Bergeron, C.3
Niznik, H.B.4
Fraser, P.E.5
|