-
1
-
-
0034612175
-
Inflammation and Alzheimer's disease
-
DOI 10.1016/S0197-4580(00)00124-X, PII S019745800000124X
-
H Akiyama S Barger S Barnum C Bradt, et al. 2000 Inflammation and Alzheimer's disease Neurobiol Aging 21 383 421 10.1016/S0197-4580(00)00124-X 10858586 (Pubitemid 30349107)
-
(2000)
Neurobiology of Aging
, vol.21
, Issue.3
, pp. 383-421
-
-
Akiyama, H.1
Barger, S.2
Barnum, S.3
Bradt, B.4
Bauer, J.5
Cole, G.M.6
Cooper, N.R.7
Eikelenboom, P.8
Emmerling, M.9
Fiebich, B.L.10
Finch, C.E.11
Frautschy, S.12
Griffin, W.S.T.13
Hampel, H.14
Hull, M.15
Landreth, G.16
Lue, L.-F.17
Mrak, R.18
MacKenzie, I.R.19
McGeer, P.L.20
O'Banion, M.K.21
Pachter, J.22
Pasinetti, G.23
Plata-Salaman, C.24
Rogers, J.25
Rydel, R.26
Shen, Y.27
Streit, W.28
Strohmeyer, R.29
Tooyoma, I.30
Van Muiswinkel, F.L.31
Veerhuis, R.32
Walker, D.33
Webster, S.34
Wegrzyniak, B.35
Wenk, G.36
Wyss-Coray, T.37
more..
-
2
-
-
0141853765
-
Amyloid-β: A chameleon walking in two worlds: A review of the trophic and toxic properties of amyloid-β
-
DOI 10.1016/S0165-0173(03)00174-7
-
CS Atwood ME Obrenovich T Liu, et al. 2003 Amyloid beta: a chameleon walking in two worlds: a review of the trophic and toxic properties of amyloid-beta Brain Res 43 1 46 10.1016/S0165-0173(03)00174-7 (Pubitemid 37130077)
-
(2003)
Brain Research Reviews
, vol.43
, Issue.1
, pp. 1-16
-
-
Atwood, C.S.1
Obrenovich, M.E.2
Liu, T.3
Chan, H.4
Perry, G.5
Smith, M.A.6
Martins, R.N.7
-
3
-
-
3042586648
-
Inflammatory mediator and β-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by vitamin E
-
DOI 10.1016/j.freeradbiomed.2004.04.007, PII S0891584904003107
-
K Ayasolla M Khan AK Singh I Singh 2004 Inflammatory mediator and beta-amyloid (25-35)-induced ceramide generation and iNOS expression are inhibited by Vitamin E Free Radic Biol Med 37 325 338 10.1016/j.freeradbiomed. 2004.04.007 15223066 (Pubitemid 38833999)
-
(2004)
Free Radical Biology and Medicine
, vol.37
, Issue.3
, pp. 325-338
-
-
Ayasolla, K.1
Khan, M.2
Singh, A.K.3
Singh, I.4
-
4
-
-
4644275696
-
Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models
-
L Baum A Ng 2004 Curcumin interaction with copper and iron suggests one possible mechanism of action in Alzheimer's disease animal models J Alzheimers Dis 6 443 449
-
(2004)
J Alzheimers Dis
, vol.6
, pp. 443-449
-
-
Baum, L.1
Ng, A.2
-
5
-
-
15944364190
-
Oxidative stress in Alzheimer's disease: Implications for prevention and therapy
-
10.1007/0-387-23226-5-3 15709473
-
C Behl 2005 Oxidative stress in Alzheimer's disease: implications for prevention and therapy Subcell Biochem 38 65 78 10.1007/0-387-23226-5-3 15709473
-
(2005)
Subcell Biochem
, vol.38
, pp. 65-78
-
-
Behl, C.1
-
6
-
-
33645105621
-
Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms
-
10.1111/j.1471-4159.2005.03578.x 16405513
-
M Bentahir O Nyabi J Verhamme A Tolia K Horre J Wiltfang H Esselmann B De Strooper 2006 Presenilin clinical mutations can affect gamma-secretase activity by different mechanisms J Neurochem 96 732 742 10.1111/j.1471-4159.2005.03578.x 16405513
-
(2006)
J Neurochem
, vol.96
, pp. 732-742
-
-
Bentahir, M.1
Nyabi, O.2
Verhamme, J.3
Tolia, A.4
Horre, K.5
Wiltfang, J.6
Esselmann, H.7
De Strooper, B.8
-
7
-
-
0035860781
-
Amyloid beta-protein oligomerization: Prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins
-
10.1074/jbc.M102223200 11441003
-
G Bitan A Lomakin DB Teplow 2001 Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins J Biol Chem 276 35176 35184 10.1074/jbc.M102223200 11441003
-
(2001)
J Biol Chem
, vol.276
, pp. 35176-35184
-
-
Bitan, G.1
Lomakin, A.2
Teplow, D.B.3
-
9
-
-
65949093025
-
Ferulic Acid-Loaded Lipid Nanostructures as Drug Delivery Systems for Alzheimer's Disease: Preparation, Characterization and Cytotoxicity Studies
-
ML Bondì G Montana EF Craparo P Picone G Capuano M Di Carlo G Giammona 2009 Ferulic Acid-Loaded Lipid Nanostructures as Drug Delivery Systems for Alzheimer's Disease: Preparation, Characterization and Cytotoxicity Studies Curr Nanosci 5 26 32
-
(2009)
Curr Nanosci
, vol.5
, pp. 26-32
-
-
Bondì, M.L.1
Montana, G.2
Craparo, E.F.3
Picone, P.4
Capuano, G.5
Di Carlo, M.6
Giammona, G.7
-
10
-
-
3843148352
-
Prefibrillar amyloid protein aggregates share common features of cytotoxicity
-
DOI 10.1074/jbc.M400348200
-
M Bucciantini G Calloni F Chiti L Formigli D Nosi CM Dobson M Stefani 2004 Prefibrillar amyloid protein aggregates share common features of cytotoxicity J Biol Chem 279 31374 31382 10.1074/jbc.M400348200 15133040 (Pubitemid 39037804)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31374-31382
-
-
Bucciantini, M.1
Calloni, G.2
Chiti, F.3
Formigli, L.4
Nosi, D.5
Dobson, C.M.6
Stefani, M.7
-
11
-
-
0026595567
-
Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs
-
1730616
-
D Burdick B Soreghan M Kwon J Kosmoski M Knauer A Henschen J Yates C Cotman C Glabe 1992 Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs J Biol Chem 267 546 554 1730616
-
(1992)
J Biol Chem
, vol.267
, pp. 546-554
-
-
Burdick, D.1
Soreghan, B.2
Kwon, M.3
Kosmoski, J.4
Knauer, M.5
Henschen, A.6
Yates, J.7
Cotman, C.8
Glabe, C.9
-
12
-
-
0037386086
-
The metallobiology of Alzheimer's disease
-
DOI 10.1016/S0166-2236(03)00067-5
-
AI Bush 2003 The metallobiology of Alzheimer's disease Trends Neurosci 26 207 214 10.1016/S0166-2236(03)00067-5 12689772 (Pubitemid 36412003)
-
(2003)
Trends in Neurosciences
, vol.26
, Issue.4
, pp. 207-214
-
-
Bush, A.I.1
-
13
-
-
0027526419
-
Release of excess amyloid beta protein from a mutant amyloid beta protein precursor
-
10.1126/science.8424174 8424174
-
XD Cai TE Golde SG Younkin 1993 Release of excess amyloid beta protein from a mutant amyloid beta protein precursor Science 259 514 516 10.1126/science.8424174 8424174
-
(1993)
Science
, vol.259
, pp. 514-516
-
-
Cai, X.D.1
Golde, T.E.2
Younkin, S.G.3
-
14
-
-
24044518189
-
Protofibril formation of amyloid β-protein at low pH via a non-cooperative elongation mechanism
-
DOI 10.1074/jbc.M500052200
-
R Carrotta M Manno D Bulone V Martorana PL San Biagio 2005 Protofibril formation of amyloid beta-protein at low pH via a non-cooperative elongation mechanism J Biol Chem 280 30001 30008 10.1074/jbc.M500052200 15985437 (Pubitemid 41216175)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.34
, pp. 30001-30008
-
-
Carrotta, R.1
Manno, M.2
Bulone, D.3
Martorana, V.4
San Biagio, P.L.5
-
15
-
-
33845566340
-
Toxicity of recombinant β-amyloid prefibrillar oligomers on the morphogenesis of the sea urchin Paracentrotus lividus
-
DOI 10.1096/fj.06-5716fje
-
R Carrotta M Di Carlo M Manno G Montana P Picone D Romancino PL San Biagio 2006 Toxicity of recombinant beta-amyloid prefibrillar oligomers on the morphogenesis of the sea urchin Paracentrotus lividus FASEB J 20 1916 1924 10.1096/fj.06-5716fje 16818470 (Pubitemid 44933778)
-
(2006)
FASEB Journal
, vol.20
, Issue.11
-
-
Carrotta, R.1
Di Carlo, M.2
Manno, M.3
Montana, G.4
Picone, P.5
Romancino, D.6
San Biagio, P.L.7
-
16
-
-
0032525741
-
In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties
-
DOI 10.1016/S0006-2952(98)00114-2, PII S0006295298001142
-
MM Chan HI Huang MR Fenton D Fong 1998 In vivo inhibition of nitric oxide synthase gene expression by curcumin, a cancer preventive natural product with anti-inflammatory properties Biochem Pharmacol 55 1955 1962 10.1016/S0006- 2952(98)00114-2 9714315 (Pubitemid 28477465)
-
(1998)
Biochemical Pharmacology
, vol.55
, Issue.12
, pp. 1955-1962
-
-
Chan, M.M.-Y.1
Huang, H.-I.2
Fenton, M.R.3
Fong, D.4
-
17
-
-
33745727582
-
Oxidative stress in Alzheimer's disease
-
10.1016/j.pathophys.2006.05.004 16781128
-
V Chauhan A Chauhan 2006 Oxidative stress in Alzheimer's disease Pathophysiology 13 195 208 10.1016/j.pathophys.2006.05.004 16781128
-
(2006)
Pathophysiology
, vol.13
, pp. 195-208
-
-
Chauhan, V.1
Chauhan, A.2
-
18
-
-
0034964390
-
Treatment with a copper-zinc chelator markedly and rapidly inhibits β-amyloid accumulation in Alzheimer's disease transgenic mice
-
DOI 10.1016/S0896-6273(01)00317-8
-
RA Cherny CS Atwood ME Xilinas, et al. 2001 Treatment with a copper-zinc chela or markedly and rapidly inhibits beta-amyloid accumulation in Alzheimer's disease transgenic mice Neuron 30 665 676 10.1016/S0896-6273(01)00317-8 11430801 (Pubitemid 32607332)
-
(2001)
Neuron
, vol.30
, Issue.3
, pp. 665-676
-
-
Cherny, R.A.1
Atwood, C.S.2
Xilinas, M.E.3
Gray, D.N.4
Jones, W.D.5
McLean, C.A.6
Barnham, K.J.7
Volitakis, I.8
Fraser, F.W.9
Kim, Y.-S.10
Huang, X.11
Goldstein, L.E.12
Moir, R.D.13
Lim, J.T.14
Beyreuther, K.15
Zheng, H.16
Tanzi, R.E.17
Masters, C.L.18
Bush, A.I.19
-
19
-
-
77952089995
-
Fibril aggregation inhibitory activity of the beta-sheet breaker peptides: A moleular docking approach
-
Chini MG, Scrima M, D'Ursi AM, Bifulco G (2008) Fibril aggregation inhibitory activity of the beta-sheet breaker peptides: a molecular docking approach. J Pept Sci Dec:16
-
(2008)
J Pept Sci Dec
, vol.16
-
-
Chini, M.G.1
Scrima, M.2
D'Ursi, A.M.3
Bifulco, G.4
-
20
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
DOI 10.1146/annurev.biochem.75.101304.123901
-
F Chiti C Dobson 2006 Protein misfolding, functional amyloid and human disease Annu Rev Biochem 75 333 366 10.1146/annurev.biochem.75.101304.123901 16756495 (Pubitemid 44118036)
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
21
-
-
0026745610
-
Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production
-
DOI 10.1038/360672a0
-
M Citron T Oltersdorf C Haass L McConlogue AY Hung P Seubert C Vigo-Pelfrey I Lieberburg DJ Selkoe 1992 Mutation of the beta-amyloid precursor protein in familial Alzheimer's disease increases beta-protein production Nature 360 672 674 10.1038/360672a0 1465129 (Pubitemid 23007680)
-
(1992)
Nature
, vol.360
, Issue.6405
, pp. 672-674
-
-
Citron, M.1
Oltersdorf, T.2
Haass, C.3
McConlogue, L.4
Hung, A.Y.5
Seubert, P.6
Vigo-Pelfrey, C.7
Lieberburg, I.8
Selkoe, D.J.9
-
22
-
-
47849124269
-
Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways
-
18525125
-
JP Cogswell J Ward IA Taylor M Waters Y Shi B Cannon K Kelnar J Kemppainen D Brown C Chen RK Prinjha JC Richardson AM Saunders AD Roses CA Richards 2008 Identification of miRNA changes in Alzheimer's disease brain and CSF yields putative biomarkers and insights into disease pathways J Alzheimers Dis 14 27 41 18525125
-
(2008)
J Alzheimers Dis
, vol.14
, pp. 27-41
-
-
Cogswell, J.P.1
Ward, J.2
Taylor, I.A.3
Waters, M.4
Shi, Y.5
Cannon, B.6
Kelnar, K.7
Kemppainen, J.8
Brown, D.9
Chen, C.10
Prinjha, R.K.11
Richardson, J.C.12
Saunders, A.M.13
Roses, A.D.14
Richards, C.A.15
-
24
-
-
0030464914
-
β-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease
-
DOI 10.1016/S0197-4580(96)00170-4, PII S0197458096001704
-
BJ Cummings CJ Pike R Shankle CW Cotman 1996 Beta-amyloid deposition and other measures of neuropathology predict cognitive status in Alzheimer's disease Neurobiol Aging 17 921 933 10.1016/S0197-4580(96)00170-4 9363804 (Pubitemid 27022746)
-
(1996)
Neurobiology of Aging
, vol.17
, Issue.6
, pp. 921-933
-
-
Cummings, B.J.1
Pike, C.J.2
Shankle, R.3
Cotman, C.W.4
-
25
-
-
0035827681
-
Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits
-
10.1074/jbc.M100175200 11274207
-
CC Curtain F Ali I Volitakis RA Cherny RS Norton K Beyreuther CJ Barrow CL Masters AI Bush KJ Barnham 2001 Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits J Biol Chem 276 20466 20473 10.1074/jbc.M100175200 11274207
-
(2001)
J Biol Chem
, vol.276
, pp. 20466-20473
-
-
Curtain, C.C.1
Ali, F.2
Volitakis, I.3
Cherny, R.A.4
Norton, R.S.5
Beyreuther, K.6
Barrow, C.J.7
Masters, C.L.8
Bush, A.I.9
Barnham, K.J.10
-
26
-
-
0037195546
-
Consistent immunohistochemical detection of intracellular β-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex
-
DOI 10.1016/S0304-3940(02)00875-3, PII S0304394002008753
-
MR D'Andrea RG Nagele HY Wang DH Lee 2002 Consistent immunohistochemical detection of intracellular beta-amyloid42 in pyramidal neurons of Alzheimer's disease entorhinal cortex Neurosci Lett 333 163 166 10.1016/S0304-3940(02)00875- 3 12429373 (Pubitemid 35335768)
-
(2002)
Neuroscience Letters
, vol.333
, Issue.3
, pp. 163-166
-
-
D'Andrea, M.R.1
Nagele, R.G.2
Wang, H.-Y.3
Lee, D.H.S.4
-
27
-
-
20444496481
-
Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers
-
DOI 10.1074/jbc.M500997200
-
A Demuro E Mina R Kayed SC Milton I Parker CG Glabe 2005 Calcium dysregulation and membrane disruption as a ubiquitous neurotoxic mechanism of soluble amyloid oligomers J Biol Chem 280 17294 17300 10.1074/jbc.M500997200 15722360 (Pubitemid 41389198)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.17
, pp. 17294-17300
-
-
Demuro, A.1
Mina, E.2
Kayed, R.3
Milton, S.C.4
Parker, I.5
Glabe, C.G.6
-
28
-
-
33745268224
-
Different conformations of amyloid β induce neurotoxicity by distinct mechanisms in human cortical neurons
-
DOI 10.1523/JNEUROSCI.1189-06.2006
-
A Deshpande E Mina C Glabe J Busciglio 2006 Different conformations of amyloid beta induce neurotoxicity by distinct mechanisms in human cortical neurons J Neurosci 26 6011 6018 10.1523/JNEUROSCI.1189-06.2006 16738244 (Pubitemid 44318367)
-
(2006)
Journal of Neuroscience
, vol.26
, Issue.22
, pp. 6011-6018
-
-
Deshpande, A.1
Mina, E.2
Glabe, C.3
Busciglio, J.4
-
29
-
-
85047693458
-
Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: Cause or effect?
-
15232608
-
DW Dickson 2004 Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? J Clin Invest 114 23 27 15232608
-
(2004)
J Clin Invest
, vol.114
, pp. 23-27
-
-
Dickson, D.W.1
-
30
-
-
0036240395
-
Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model
-
11941374
-
JC Dodart KR Bales KS Gannon SJ Greene RB DeMattos C Mathis CA DeLong S Wu X Wu DM Holtzman SM Paul 2002 Immunization reverses memory deficits without reducing brain Abeta burden in Alzheimer's disease model Nat Neurosci 5 452 457 11941374
-
(2002)
Nat Neurosci
, vol.5
, pp. 452-457
-
-
Dodart, J.C.1
Bales, K.R.2
Gannon, K.S.3
Greene, S.J.4
Demattos, R.B.5
Mathis, C.6
Delong, C.A.7
Wu, S.8
Wu, X.9
Holtzman, D.M.10
Paul, S.M.11
-
31
-
-
0035163347
-
Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain
-
DOI 10.1046/j.1471-4159.2001.00012.x
-
HF Dovey V John JP Anderson, et al. 2001 Functional gamma-secretase inhibitors reduce beta-amyloid peptide levels in brain J Neurochem 76 173 181 10.1046/j.1471-4159.2001.00012.x 11145990 (Pubitemid 32044380)
-
(2001)
Journal of Neurochemistry
, vol.76
, Issue.1
, pp. 173-181
-
-
Dovey, H.F.1
John, V.2
Anderson, J.P.3
Chen, L.Z.4
De Saint Andrieu, P.5
Fang, L.Y.6
Freedman, S.B.7
Folmer, B.8
Goldbach, E.9
Holsztynska, E.J.10
Hu, K.L.11
Johnson-Wood, K.L.12
Kennedy, S.L.13
Kholodenko, D.14
Knops, J.E.15
Latimer, L.H.16
Lee, M.17
Liao, Z.18
Lieberburg, I.M.19
Motter, R.N.20
Mutter, L.C.21
Nietz, J.22
Quinn, K.P.23
Sacchi, K.L.24
Seubert, P.A.25
Shopp, G.M.26
Thorsett, E.D.27
Tung, J.S.28
Wu, J.29
Yang, S.30
Yin, C.T.31
Schenk, D.B.32
May, P.C.33
Altstiel, L.D.34
Bender, M.H.35
Boggs, L.N.36
Britton, T.C.37
Clemens, J.C.38
Czilli, D.L.39
Dieckman-McGinty, D.K.40
Droste, J.J.41
Fuson, K.S.42
Gitter, B.D.43
Hyslop, P.A.44
Johnstone, E.M.45
Li, W.-Y.46
Little, S.P.47
Mabry, T.E.48
Miller, F.D.49
Ni, B.50
Nissen, J.S.51
Porter, W.J.52
Potts, B.D.53
Reel, J.K.54
Stephenson, D.55
Su, Y.56
Shipley, L.A.57
Whitesitt, C.A.58
Yin, T.59
Audia, J.E.60
more..
-
32
-
-
0033807836
-
An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments
-
10.3109/13506120009146831 11019857
-
Y Fezoui DM Hartley JD Harper R Khurana DM Walsh MM Condron DJ Selkoe PT Lansbury Jr AL Fink DB Teplow 2000 An improved method of preparing the amyloid beta-protein for fibrillogenesis and neurotoxicity experiments Amyloid 7 166 178 10.3109/13506120009146831 11019857
-
(2000)
Amyloid
, vol.7
, pp. 166-178
-
-
Fezoui, Y.1
Hartley, D.M.2
Harper, J.D.3
Khurana, R.4
Walsh, D.M.5
Condron, M.M.6
Selkoe, D.J.7
Lansbury Jr, P.T.8
Fink, A.L.9
Teplow, D.B.10
-
33
-
-
34548812551
-
The role of amyloid β peptide 42 in Alzheimer's disease
-
DOI 10.1016/j.pharmthera.2007.06.006, PII S016372580700143X
-
MA Findeis 2007 The role of amyloid beta peptide 42 in Alzhiemer's disease Pharmacol Ther 116 266 286 10.1016/j.pharmthera.2007.06.006 17716740 (Pubitemid 47451506)
-
(2007)
Pharmacology and Therapeutics
, vol.116
, Issue.2
, pp. 266-286
-
-
Findeis, M.A.1
-
35
-
-
0031824782
-
Aging renders the brain vulnerable to 26 β-protein neurotoxicity
-
DOI 10.1038/nm0798-827
-
C Geula CK Wu D Saroff A Lorenzo M Yuan BA Yankner 1998 Aging renders the brain vulnerable to amyloid beta-protein neurotoxicity Nat Med 4 827 831 10.1038/nm0798-827 9662375 (Pubitemid 28331025)
-
(1998)
Nature Medicine
, vol.4
, Issue.7
, pp. 827-831
-
-
Geula, C.1
Wu, C.-K.2
Saroff, D.3
Lorenzo, A.4
Yuan, M.5
Yankner, B.A.6
-
36
-
-
0035159785
-
Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease
-
DOI 10.1385/JMN:17:2:137
-
C Glabe 2001 Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease J Mol Neurosci 17 137 145 10.1385/JMN:17:2:137 11816787 (Pubitemid 33063518)
-
(2001)
Journal of Molecular Neuroscience
, vol.17
, Issue.2
, pp. 137-145
-
-
Glabe, C.1
-
37
-
-
0021256895
-
Alzheimer's disease: Initial report of the purification and characterization of a novel cerebrovascular amyloid protein
-
G Glenner CW Wong 1984 Alzheimer's disease: initial report of the purification and characterization of a novel cerebrovascular amyloid protein Biochem Biophys Res Commun 120 885 890 10.1016/S0006-291X(84)80190-4 6375662 (Pubitemid 14104991)
-
(1984)
Biochemical and Biophysical Research Communications
, vol.120
, Issue.3
, pp. 885-890
-
-
Glenner, G.G.1
Wong, C.W.2
-
38
-
-
0042838303
-
Alzheimer's disease-affected brain: Presence of oligomeric Aβ ligands (ADDLs) suggests a molecular basis for reversible memory loss
-
DOI 10.1073/pnas.1834302100
-
Y Gong L Chang KL Viola PN Lacor MP Lambert CE Finch GA Krafft WL Klein 2003 Alzheimer's disease-affected brain: presence of oligomeric A beta ligands (ADDLs) suggests a molecular basis for reversible memory loss Proc Natl Acad Sci USA 100 18 10417 10422 10.1073/pnas.1834302100 12925731 (Pubitemid 37071893)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.18
, pp. 10417-10422
-
-
Gong, Y.1
Chang, L.2
Viola, K.L.3
Lacor, P.N.4
Lambert, M.P.5
Finch, C.E.6
Krafft, G.A.7
Klein, W.L.8
-
39
-
-
0036898485
-
Alzheimer disease γ-secretase: A complex story of GxGD-type presenilin proteases
-
DOI 10.1016/S0962-8924(02)02394-2, PII S0962892402023942
-
C Haass H Steiner 2002 Alzheimer disease gamma-secretase: a complex story of GxGD-type presenilin proteases Trends Cell Biol 12 556 562 10.1016/S0962-8924(02)02394-2 12495843 (Pubitemid 35461853)
-
(2002)
Trends in Cell Biology
, vol.12
, Issue.12
, pp. 556-562
-
-
Haass, C.1
Steiner, H.2
-
40
-
-
0031444010
-
Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-beta protein
-
10.1016/S1074-5521(97)90303-3 9427660
-
JD Harper SS Wong CM Lieber PT Lansbury 1997 Atomic force microscopic imaging of seeded fibril formation and fibril branching by the Alzheimer's disease amyloid-beta protein Chem Biol 4 951 959 10.1016/S1074-5521(97)90303-3 9427660
-
(1997)
Chem Biol
, vol.4
, pp. 951-959
-
-
Harper, J.D.1
Wong, S.S.2
Lieber, C.M.3
Lansbury, P.T.4
-
41
-
-
77952099371
-
MicroRNA regulation of Alzheimer's Amyloid precursor protein expression
-
Hébert SS, Horré K, Nicolaï L, Bergmans B, Papadopoulou AS, Delacourte A, De Strooper B (2008) MicroRNA regulation of Alzheimer's Amyloid precursor protein expression. Neurobiol Dis Dec:9
-
(2008)
Neurobiol Dis Dec
, vol.9
-
-
Hébert, S.S.1
Horré, K.2
Nicolaï, L.3
Bergmans, B.4
Papadopoulou, A.S.5
Delacourte, A.6
De Strooper, B.7
-
42
-
-
0036191829
-
Mapping of possible binding sequences of two beta-sheet breaker peptides on beta amyloid peptide of Alzheimer's disease
-
DOI 10.1016/S0968-0896(01)00424-2, PII S0968089601004242
-
C Hetényi T Körtvélyesi B Penke 2002 Mapping of possible binding sequences of two bet -sheet breaker peptides on beta amyloid peptide of Alzheimer's disease Bioorg Med Chem 10 1587 1593 10.1016/S0968- 0896(01)00424-2 11886820 (Pubitemid 34214721)
-
(2002)
Bioorganic and Medicinal Chemistry
, vol.10
, Issue.5
, pp. 1587-1593
-
-
Hetenyi, C.1
Kortvelyesi, T.2
Penke, B.3
-
43
-
-
0038100154
-
Antibodies against β-amyloid slow cognitive decline in Alzheimer's disease
-
DOI 10.1016/S0896-6273(03)00294-0
-
C Hock U Konietzko JR Streffer, et al. 2003 Antibodies against beta-amyloid slow cognitive decline in Alzheimer's disease Neuron 38 547 554 10.1016/S0896-6273(03)00294-0 12765607 (Pubitemid 36645030)
-
(2003)
Neuron
, vol.38
, Issue.4
, pp. 547-554
-
-
Hock, C.1
Konietzko, U.2
Streffer, J.R.3
Tracy, J.4
Signorell, A.5
Muller-Tillmanns, B.6
Lemke, U.7
Henke, K.8
Moritz, E.9
Garcia, E.10
Wollmer, M.A.11
Umbricht, D.12
De Quervain, D.J.F.13
Hofmann, M.14
Maddalena, A.15
Papassotiropoulos, A.16
Nitsch, R.M.17
-
44
-
-
0027485461
-
Bcl-2 functions in an antioxidant pathway to prevent apoptosis
-
DOI 10.1016/0092-8674(93)80066-N
-
DM Hockenbery ZN Oltvai XM Yin CL Milliman SJ Korsmeyer 1993 Bcl-2 functions in an antioxidant pathway to prevent apoptosis Cell 75 241 251 10.1016/0092-8674(93)80066-N 7503812 (Pubitemid 23320288)
-
(1993)
Cell
, vol.75
, Issue.2
, pp. 241-251
-
-
Hockenbery, D.M.1
Oltvai, Z.N.2
Yin, X.-M.3
Milliman, C.L.4
Korsmeyer, S.J.5
-
45
-
-
0037975676
-
Spherical aggregates of β-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3β
-
DOI 10.1073/pnas.1237107100
-
M Hoshi M Sato S Matsumoto A Noguchi K Yasutake N Yoshida K Sato 2003 Spherical aggregates of beta-amyloid (amylospheroid) show high neurotoxicity and activate tau protein kinase I/glycogen synthase kinase-3beta Proc Natl Acad Sci USA 100 6370 6375 10.1073/pnas.1237107100 12750461 (Pubitemid 36666588)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.11
, pp. 6370-6375
-
-
Hoshi, M.1
Sato, M.2
Matsumoto, S.3
Noguchi, A.4
Yasutake, K.5
Yoshida, N.6
Sato, K.7
-
48
-
-
34249089845
-
Role of caspase-12 in amyloid β-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods
-
DOI 10.1254/jphs.FP0061533
-
K Ishige N Takagi T Imai WD Rausch Y Kosuge T Kihara K Kusama-Eguchi H Ikeda AR Cools JL Waddington N Koshikawa Y Ito 2007 Role of caspase-12 in amyloid beta-peptide-induced toxicity in organotypic hippocampal slices cultured for long periods J Pharmacol Sci 104 46 55 10.1254/jphs.FP0061533 17452809 (Pubitemid 46790315)
-
(2007)
Journal of Pharmacological Sciences
, vol.104
, Issue.1
, pp. 46-55
-
-
Ishige, K.1
Takagi, N.2
Imai, T.3
Rausch, W.D.4
Kosuge, Y.5
Kihara, T.6
Kusama-Eguchi, K.7
Ikeda, H.8
Cools, A.R.9
Waddington, J.L.10
Koshikawa, N.11
Ito, Y.12
-
49
-
-
0027258525
-
The carboxy terminus of the β amyloid protein is critical for the seeding of amyloid formation: Implications for the pathogenesis of Alzheimer's disease
-
DOI 10.1021/bi00069a001
-
JT Jarrett EP Berger PT Lansbury Jr 1993 The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease Biochemistry 32 4693 7469 10.1021/bi00069a001 8490014 (Pubitemid 23162022)
-
(1993)
Biochemistry
, vol.32
, Issue.18
, pp. 4693-4697
-
-
Jarrett, J.T.1
Berger, E.P.2
Lansbury Jr., P.T.3
-
50
-
-
61749086594
-
FTIR spectroscopic studies on aggregation process of the beta-amyloid 11-28 fragment and its variants
-
10.1002/psc.1085 19023881
-
P Juszczyk AS Kołodziejczyk Z Grzonka 2009 FTIR spectroscopic studies on aggregation process of the beta-amyloid 11-28 fragment and its variants J Pept Sci 15 23 29 10.1002/psc.1085 19023881
-
(2009)
J Pept Sci
, vol.15
, pp. 23-29
-
-
Juszczyk, P.1
Kołodziejczyk, A.S.2
Grzonka, Z.3
-
51
-
-
0037184817
-
History of the events leading to the formulation of the apoptosis concept
-
DOI 10.1016/S0300-483X(02)00457-2, PII S0300483X02004572
-
JF Kerr 2002 History of the events leading to the formulation of the apoptosis concept Toxicology 182 471 474 10.1016/S0300-483X(02)00457-2 (Pubitemid 36015740)
-
(2002)
Toxicology
, vol.181-182
, pp. 471-474
-
-
Kerr, J.F.R.1
-
52
-
-
0037013327
-
Intracellular amyloid-β1-42, but not extracellular soluble amyloid-β peptides, induces neuronal apoptosis
-
DOI 10.1074/jbc.M200887200
-
P Kienlen-Campard S Miolet B Tasiaux JN Octave 2002 Intracellular amyloid-beta 1-42, but not extracellular soluble amyloid-beta peptides, induces neuronal apoptosis Biol Chem 277 15666 15670 10.1074/jbc.M200887200 (Pubitemid 34967839)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.18
, pp. 15666-15670
-
-
Kienlen-Campard, P.1
Miolet, S.2
Tasiaux, B.3
Octave, J.-N.4
-
53
-
-
0038400956
-
Immunocytochemical evidence that amyloid β (1-42) impairs endogenous antioxidant systems in vivo
-
DOI 10.1016/S0306-4522(02)00993-4
-
HC Kim K Yamada A Nitta 2003 Immunocytochemical evidence that amyloid beta (1-42) impairs endogenous antioxidant systems in vivo Neuroscience 119 399 419 10.1016/S0306-4522(02)00993-4 12770555 (Pubitemid 36588819)
-
(2003)
Neuroscience
, vol.119
, Issue.2
, pp. 399-419
-
-
Kim, H.-C.1
Yamada, K.2
Nitta, A.3
Olariu, A.4
Tran, M.H.5
Mizuno, M.6
Nakajima, A.7
Nagai, T.8
Kamei, H.9
Jhoo, W.-K.10
Im, D.-H.11
Shin, E.-J.12
Hjelle, O.P.13
Ottersen, O.P.14
Park, S.C.15
Kato, K.16
Mirault, M.-E.17
Nabeshima, T.18
-
54
-
-
23644459835
-
Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease
-
15933761
-
MD Kirkitadze A Kowalska 2005 Molecular mechanisms initiating amyloid beta-fibril formation in Alzheimer's disease Acta Biochim Pol 52 417 423 15933761
-
(2005)
Acta Biochim Pol
, vol.52
, pp. 417-423
-
-
Kirkitadze, M.D.1
Kowalska, A.2
-
55
-
-
0022547855
-
X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation
-
10.1073/pnas.83.2.503 3455785
-
DA Kirschner C Abraham DJ Selkoe 1986 X-ray diffraction from intraneuronal paired helical filaments and extraneuronal amyloid fibers in Alzheimer disease indicates cross-beta conformation Proc Natl Acad Sci USA 83 503 507 10.1073/pnas.83.2.503 3455785
-
(1986)
Proc Natl Acad Sci USA
, vol.83
, pp. 503-507
-
-
Kirschner, D.A.1
Abraham, C.2
Selkoe, D.J.3
-
56
-
-
21044453723
-
Amyloid β protein immunotherapy neutralizes Aβ oligomers that disrupt synaptic plasticity in vivo
-
DOI 10.1038/nm1234
-
I Klyubin DM Walsh CA Lemere WK Cullen GM Shankar V Betts ET Spooner L Jiang R Anwyl DJ Selkoe MJ Rowan 2005 Amyloid beta protein immunotherapy neutralizes Abeta oligomers that disrupt synaptic plasticity in vivo Nat Med 11 556 561 10.1038/nm1234 15834427 (Pubitemid 40685979)
-
(2005)
Nature Medicine
, vol.11
, Issue.5
, pp. 556-561
-
-
Klyubin, I.1
Walsh, D.M.2
Lemere, C.A.3
Cullen, W.K.4
Shankar, G.M.5
Betts, V.6
Spooner, E.T.7
Jiang, L.8
Anwyl, R.9
Selkoe, D.J.10
Rowan, M.J.11
-
57
-
-
33745700370
-
Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40
-
10.1002/humu.20336 16752394
-
S Kumar-Singh J Theuns B Van Broeck D Pirici K Vennekens E Corsmit M Cruts B Dermaut R Wang C Van Broeckhoven 2006 Mean age-of-onset of familial alzheimer disease caused by presenilin mutations correlates with both increased Abeta42 and decreased Abeta40 Hum Mutat 27 686 695 10.1002/humu.20336 16752394
-
(2006)
Hum Mutat
, vol.27
, pp. 686-695
-
-
Kumar-Singh, S.1
Theuns, J.2
Van Broeck, B.3
Pirici, D.4
Vennekens, K.5
Corsmit, E.6
Cruts, M.7
Dermaut, B.8
Wang, R.9
Van Broeckhoven, C.10
-
58
-
-
11544279355
-
1-42 are potent central nervous system neurotoxins
-
DOI 10.1073/pnas.95.11.6448
-
1-42 are potent central nervous system neurotoxins Proc Natl Acad Sci USA 95 6448 6453 10.1073/pnas.95.11.6448 9600986 (Pubitemid 28249033)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.11
, pp. 6448-6453
-
-
Lambert, M.P.1
Barlow, A.K.2
Chromy, B.A.3
Edwards, C.4
Freed, R.5
Liosatos, M.6
Morgan, T.E.7
Rozovsky, I.8
Trommer, B.9
Viola, K.L.10
Wals, P.11
Zhang, C.12
Finch, C.E.13
Krafft, G.A.14
Klein, W.L.15
-
59
-
-
0035503597
-
The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse
-
11606625
-
GP Lim T Chu F Yang W Beech SA Frautschy GM Cole 2001 The curry spice curcumin reduces oxidative damage and amyloid pathology in an Alzheimer transgenic mouse J Neurosci 21 8370 8377 11606625
-
(2001)
J Neurosci
, vol.21
, pp. 8370-8377
-
-
Lim, G.P.1
Chu, T.2
Yang, F.3
Beech, W.4
Frautschy, S.A.5
Cole, G.M.6
-
60
-
-
32844465483
-
Cytokine production by a human microglial cell line: Effects of beta-amyloid and alpha-melanocyte-stimulating hormone
-
16371321
-
C Lindberg E Hjorth C Post B Winblad M Schultzberg 2005 Cytokine production by a human microglial cell line: effects of beta-amyloid and alpha-melanocyte-stimulating hormone Neurotox Res 8 267 276 16371321
-
(2005)
Neurotox Res
, vol.8
, pp. 267-276
-
-
Lindberg, C.1
Hjorth, E.2
Post, C.3
Winblad, B.4
Schultzberg, M.5
-
61
-
-
0033587478
-
Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the Aβ peptide of Alzheimer's disease
-
DOI 10.1021/bi990205o
-
ST Liu G Howlett CJ Barrow 1999 Histidine-13 is a crucial residue in the zinc ion-induced aggregation of the A beta peptide of Alzheimer's disease Biochemistry 38 9373 9378 10.1021/bi990205o 10413512 (Pubitemid 29347261)
-
(1999)
Biochemistry
, vol.38
, Issue.29
, pp. 9373-9378
-
-
Liu, S.-T.1
Howlett, G.2
Barrow, C.J.3
-
64
-
-
0032766155
-
Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats
-
10419543
-
Y Luo A Hattori J Munoz Z Qin G Roth 1999 Intrastriatal dopamine injection induces apoptosis through oxidation-involved activation of transcription factors AP-1 and NF-kappaB in rats Mol Pharmacol 56 254 264 10419543
-
(1999)
Mol Pharmacol
, vol.56
, pp. 254-264
-
-
Luo, Y.1
Hattori, A.2
Munoz, J.3
Qin, Z.4
Roth, G.5
-
65
-
-
21544465581
-
An alternative interpretation of the amyloid Aβ hypothesis with regard to the pathogenesis of Alzheimer's disease
-
DOI 10.1073/pnas.0503181102
-
VT Marchesi 2005 An alternative interpretation of the amyloid Abeta hypothesis with regard to the pathogenesis of Alzheimer's disease Proc Natl Acad Sci USA 102 9093 9098 10.1073/pnas.0503181102 15967987 (Pubitemid 40923523)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.26
, pp. 9093-9098
-
-
Marchesi, V.T.1
-
68
-
-
0035693924
-
Inflammation, autotoxicity and Alzheimer disease
-
DOI 10.1016/S0197-4580(01)00289-5, PII S0197458001002895
-
PL McGeer EG McGerr 2001 Inflammation autotoxicity and Alzheimer's disease Neurobiol Aging 22 799 809 10.1016/S0197-4580(01)00289-5 11754986 (Pubitemid 34066546)
-
(2001)
Neurobiology of Aging
, vol.22
, Issue.6
, pp. 799-809
-
-
McGeer, P.L.1
McGeer, E.G.2
-
69
-
-
0036852750
-
Therapeutically effective antibodies against amyloid-β peptide target amyloid-β residues 4-10 and inhibit cytotoxicity and fibrillogenesis
-
DOI 10.1038/nm790
-
J McLaurin R Cecal ME Kierstead X Tian AL Phinney M Manea, et al. 2002 Therapeutically effective antibodies against amyloid-beta peptide target amyloid-beta residues 4-10 and inhibit cytotoxicity and fibrillogenesis Nat Med 8 1263 1269 10.1038/nm790 12379850 (Pubitemid 35373558)
-
(2002)
Nature Medicine
, vol.8
, Issue.11
, pp. 1263-1269
-
-
McLaurin, J.1
Cecal, R.2
Kierstead, M.E.3
Tian, X.4
Phinney, A.L.5
Manea, M.6
French, J.E.7
Lambermon, M.H.L.8
Darabie, A.A.9
Brown, M.E.10
Janus, C.11
Chishti, M.A.12
Horne, P.13
Westaway, D.14
Fraser, P.E.15
Mount, H.T.J.16
Przybylski, M.17
St George-Hyslop, P.18
-
71
-
-
4444304720
-
APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: Implications for Alzheimer's disease
-
DOI 10.1016/j.neulet.2004.06.077, PII S0304394004008420
-
AH Mohmmad GL Wenk M Gramling B Hauss-Wegrzyniak DA Butterfield 2004 APP and PS-1 mutations induce brain oxidative stress independent of dietary cholesterol: implications for Alzheimer's disease Neurosci Lett 368 148 150 10.1016/j.neulet.2004.06.077 (Pubitemid 39194861)
-
(2004)
Neuroscience Letters
, vol.368
, Issue.2
, pp. 148-150
-
-
Mohmmad Abdul, H.1
Wenk, G.L.2
Gramling, M.3
Hauss-Wegrzyniak, B.4
Butterfield, D.A.5
-
72
-
-
0034610743
-
Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β
-
DOI 10.1038/47513
-
T Nakagawa H Zhu N Morishima E Li J Xu BA Yankner J Yuan 2000 Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta Nature 403 98 103 10.1038/47513 10638761 (Pubitemid 30038529)
-
(2000)
Nature
, vol.403
, Issue.6765
, pp. 98-103
-
-
Nakagawa, T.1
Zhu, H.2
Morishima, N.3
Li, E.4
Xu, J.5
Yankner, B.A.6
Yuan, J.7
-
73
-
-
0034644836
-
Regulation of APP cleavage by alpha-, beta- and gamma-secretases
-
10.1016/S0014-5793(00)02076-7
-
J Nunam DH Small 2000 Regulation of APP cleavage by alpha-, beta- and gamma-secretases FEBS Lett 483 6 10 10.1016/S0014-5793(00)02076-7
-
(2000)
FEBS Lett
, vol.483
, pp. 6-10
-
-
Nunam, J.1
Small, D.H.2
-
74
-
-
0344845132
-
Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease
-
DOI 10.1016/j.neurobiolaging.2003.08.012
-
S Oddo A Caccamo JD Shepherd MP Murphy TE Golde R Kayed R Metherate MP Mattson Y Akb ri FM LaFerla 2003 Amyloid deposition precedes tangle formation in a triple transgenic model of Alzheimer's disease Neurobiol Aging 24 1063 1070 10.1016/j.neurobiolaging.2003.08.012 14643377 (Pubitemid 37487883)
-
(2003)
Neurobiology of Aging
, vol.24
, Issue.8
, pp. 1063-1070
-
-
Oddo, S.1
Caccamo, A.2
Kitazawa, M.3
Tseng, B.P.4
LaFerla, F.M.5
-
75
-
-
24644438783
-
Ferulic acid destabilizes preformed beta-amyloid fibrils in vitro
-
Ono K, Hirohata M, Yamada M (2005) Ferulic acid destabilizes preformed beta-amyloid fibrils in vitro. Biochem Biophys Res Commun 21:336, 444
-
(2005)
Biochem Biophys Res Commun
, vol.21
, pp. 444
-
-
Ono, K.1
Hirohata, M.2
Yamada, M.3
-
76
-
-
0037355742
-
Copper reduction by copper binding proteins and its relation to neurodegenerative diseases
-
DOI 10.1023/A:1020795422185
-
C Opazo MI Barria FH Ruiz NC Inestrosa 2003 Copper reduction by copper binding proteins and its relation to neurodegenerative diseases Biometals 16 91 98 10.1023/A:1020795422185 12572668 (Pubitemid 36140219)
-
(2003)
BioMetals
, vol.16
, Issue.1
, pp. 91-98
-
-
Opazo, C.1
Ines Barria, M.2
Ruiz, F.H.3
Inestrosa, N.C.4
-
77
-
-
68049131389
-
Aβ oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures
-
P Picone R Carrotta G Montana MR Nobile PL San Biagio M Di Carlo 2009 Aβ oligomers and fibrillar aggregates induce different apoptotic pathways in LAN5 neuroblastoma cell cultures Biophys J 96 1 12
-
(2009)
Biophys J
, vol.96
, pp. 1-12
-
-
Picone, P.1
Carrotta, R.2
Montana, G.3
Nobile, M.R.4
San Biagio, P.L.5
Di Carlo, M.6
-
78
-
-
57649221161
-
Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: Lights and shadows
-
19076432
-
D Praticò 2008 Evidence of oxidative stress in Alzheimer's disease brain and antioxidant therapy: lights and shadows Ann N Y Acad Sci 1147 70 78 19076432
-
(2008)
Ann N y Acad Sci
, vol.1147
, pp. 70-78
-
-
Praticò, D.1
-
79
-
-
37249062072
-
Internalization of β-amyloid peptide by primary neurons in the absence of apolipoprotein E
-
DOI 10.1074/jbc.M701823200
-
L Saavedra A Mohamed V Ma Kar Posse S de Chaves 2007 Internalization of beta-amyloid peptide by primary neurons in the absence of apolipoprotein E J Biol Chem 282 35722 35732 10.1074/jbc.M701823200 17911110 (Pubitemid 350277136)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.49
, pp. 35722-35732
-
-
Saavedra, L.1
Mohamed, A.2
Ma, V.3
Kar, S.4
De Chaves, E.P.5
-
80
-
-
0042878457
-
The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of κB kinase, and NFκB, do not reduce amyloid β42 production
-
DOI 10.1074/jbc.M303588200
-
SA Sagi S Weggen J Eriksen TE Golde EH Koo 2003 The non-cyclooxygenase targets of non-steroidal anti-inflammatory drugs, lipoxygenases, peroxisome proliferator-activated receptor, inhibitor of kappa B kinase, and NF kappa B, do not reduce amyloid beta 42 production J Biol Chem 278 31825 31830 10.1074/jbc.M303588200 12805355 (Pubitemid 37048364)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.34
, pp. 31825-31830
-
-
Sagi, S.A.1
Weggen, S.2
Eriksen, J.3
Golde, T.E.4
Koo, E.H.5
-
81
-
-
33646691510
-
Curcumin activates defensive genes and protects neurons against oxidative stress
-
DOI 10.1089/ars.2006.8.395
-
G Scapagnini C Colombrita M Amadio V D'Agata E Arcelli M Sapienza A Quattrone V Calabrese 2006 Curcumin activates defensive genes and protects neurons against oxidative stress Antioxid Redox Signal 8 395 403 10.1089/ars.2006.8.395 16677086 (Pubitemid 43741311)
-
(2006)
Antioxidants and Redox Signaling
, vol.8
, Issue.3-4
, pp. 395-403
-
-
Scapagnini, G.1
Colombrita, C.2
Amadio, M.3
D'Agata, V.4
Arcelli, E.5
Sapienza, M.6
Quattrone, A.7
Calabrese, V.8
-
82
-
-
0033536163
-
Immunization with amyloid-β attenuates Alzheimer disease-like pathology in the PDAPP mouse
-
DOI 10.1038/22124
-
D Schenk R Barbour W Dunn, et al. 1999 Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse Nature 400 173 177 10.1038/22124 1040844 (Pubitemid 29327547)
-
(1999)
Nature
, vol.400
, Issue.6740
, pp. 173-177
-
-
Schenk, D.1
Barbour, R.2
Dunn, W.3
Gordon, G.4
Grajeda, H.5
Guldo, T.6
Hu, K.7
Huang, J.8
Johnson-Wood, K.9
Khan, K.10
Kholodenko, D.11
Lee, M.12
Liao, Z.13
Lieberburg, I.14
Motter, R.15
Mutter, L.16
Soriano, F.17
Shopp, G.18
Vasquez, N.19
Vandevert, C.20
Walker, S.21
Wogulis, M.22
Yednock, T.23
Games, D.24
Seubert, P.25
more..
-
83
-
-
0033600274
-
Translating cell biology into therapeutic advances in Alzheimer's disease
-
Selkoe DJ (1999) Translating cell biology into therapeutic advances in Alzheimer's disease. Nature 399:A23-A31
-
(1999)
Nature
, vol.399
-
-
Selkoe, D.J.1
-
84
-
-
0034718157
-
Alzheimer's amyloid fibrils: Structure and assembly
-
10899428
-
LC Serpell 2000 Alzheimer's amyloid fibrils: structure and assembly Biochim Biophys Acta 1502 16 20 10899428
-
(2000)
Biochim Biophys Acta
, vol.1502
, pp. 16-20
-
-
Serpell, L.C.1
-
85
-
-
53049095484
-
In vitro perturbation of aggregation processes in beta-amyloid peptides: A spectroscopic study
-
10.1016/j.febslet.2008.08.039 18805418
-
A Sgarbossa D Buselli F Lenci 2008 In vitro perturbation of aggregation processes in beta-amyloid peptides: a spectroscopic study FEBS Lett 582 3288 3292 10.1016/j.febslet.2008.08.039 18805418
-
(2008)
FEBS Lett
, vol.582
, pp. 3288-3292
-
-
Sgarbossa, A.1
Buselli, D.2
Lenci, F.3
-
87
-
-
0027988116
-
Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation
-
B Sorenghan J Kosmoski C Glabe 1994 Surfactant properties of Alzheimer's A beta peptides and the mechanism of amyloid aggregation J Biol Chem 269 28551 28554
-
(1994)
J Biol Chem
, vol.269
, pp. 28551-28554
-
-
Sorenghan, B.1
Kosmoski, J.2
Glabe, C.3
-
88
-
-
33644817173
-
Metal binding in amyloid β-peptides shows intra- and inter-peptide coordination modes
-
DOI 10.1007/s00249-005-0041-7
-
F Stellato G Minestrina M Dalla Serra C Potrich R Tomazzolli W Meyer-Klaucke S Morante 2006 Metal binding in amyloid b-peptides shows intra- and inter-peptide coordination modes Eur Biophys J 35 340 351 10.1007/s00249-005-0041-7 16404590 (Pubitemid 43357588)
-
(2006)
European Biophysics Journal
, vol.35
, Issue.4
, pp. 340-351
-
-
Stellato, F.1
Menestrina, G.2
Serra, M.D.3
Potrich, C.4
Tomazzolli, R.5
Meyer-Klaucke, W.6
Morante, S.7
-
90
-
-
0028322017
-
An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants
-
10.1126/science.8191290 8191290
-
N Suzuki TT Cheung XD Cai A Odaka L Otvos Jr C Eckman TE Golde SG Younkin 1994 An increased percentage of long amyloid beta protein secreted by familial amyloid beta protein precursor (beta APP717) mutants Science 264 1336 1340 10.1126/science.8191290 8191290
-
(1994)
Science
, vol.264
, pp. 1336-1340
-
-
Suzuki, N.1
Cheung, T.T.2
Cai, X.D.3
Odaka, A.4
Otvos Jr, L.5
Eckman, C.6
Golde, T.E.7
Younkin, S.G.8
-
91
-
-
0034811903
-
Inhibitory effect of copper(II) on zinc(II)-induced aggregation of amyloid β-peptide
-
DOI 10.1006/bbrc.2001.5263
-
K Suzuki T Miura H Takeuchi 2001 Inhibitory effect of copper(II) on zinc(II)-induced aggregation of amyloid b-peptide Biochem Biophys Res Commun 285 991 996 10.1006/bbrc.2001.5263 11467850 (Pubitemid 32918035)
-
(2001)
Biochemical and Biophysical Research Communications
, vol.285
, Issue.4
, pp. 991-996
-
-
Suzuki, K.1
Miura, T.2
Takeuchi, H.3
-
92
-
-
0033781375
-
Subacute myelo-optico-neuropathy: Clioquinol intoxication in humans and animals
-
10.1046/j.1440-178 .2000.00296.x
-
J Tateishi 2000 Subacute myelo-optico-neuropathy: clioquinol intoxication in humans and animals Neuropathology 20 20 24 10.1046/j.1440-1789.2000.00296.x
-
(2000)
Neuropathology
, vol.20
, pp. 20-24
-
-
Tateishi, J.1
-
93
-
-
33749535361
-
Preparation of Amyloid β-Protein for Structural and Functional Studies
-
DOI 10.1016/S0076-6879(06)13002-5, PII S0076687906130025, Amyloid, Prions, and Other Protein Aggregates, Part C
-
DB Teplow 2006 Preparation of amyloid beta-protein for structural and functional studies Methods Enzymol 413 20 33 10.1016/S0076-6879(06)13002-5 17046389 (Pubitemid 44528683)
-
(2006)
Methods in Enzymology
, vol.413
, pp. 20-33
-
-
Teplow, D.B.1
-
94
-
-
0037465708
-
Insights into the amyloid folding problem from solid-state NMR
-
DOI 10.1021/bi027378p
-
R Tycko 2003 Insights into the amyloid folding problem from solid-state NMR Biochemistry 42 3151 3159 10.1021/bi027378p 12641446 (Pubitemid 36348623)
-
(2003)
Biochemistry
, vol.42
, Issue.11
, pp. 3151-3159
-
-
Tycko, R.1
-
95
-
-
34249708824
-
Zinc and inflammatory/immune response in aging
-
DOI 10.1196/annals.1395.009, Biogerontology: Mechanisms and Interventions
-
S Vasto E Moccheggiani M Malavolta, et al. 2007 Zn and inflammatory/immune response in aging Ann N Y Acad Sci 1100 111 122 10.1196/annals.1395.009 17460169 (Pubitemid 47092643)
-
(2007)
Annals of the New York Academy of Sciences
, vol.1100
, pp. 111-122
-
-
Vasto, S.1
Mocchegiani, E.2
Malavolta, M.3
Cuppari, I.4
Listi, F.5
Nuzzo, D.6
Ditta, V.7
Candore, G.8
Caruso, C.9
-
96
-
-
45549109796
-
Inflammation, genes and Zn in Alzheimer's disease
-
10.1016/j.brainresrev.2007.12.001
-
S Vasto G Candore F Listi, et al. 2008 Inflammation, genes and Zn in Alzheimer's disease Brain Res Brain Res Rev 58 96 105 10.1016/j.brainresrev. 2007.12.001
-
(2008)
Brain Res Brain Res Rev
, vol.58
, pp. 96-105
-
-
Vasto, S.1
Candore, G.2
Listi, F.3
-
97
-
-
2342495787
-
Amyloid β-peptide interactions with neuronal and glial cell plasma membrane: Binding sites and implications for Alzheimer's disease
-
DOI 10.1002/psc.573
-
Y Verdier M Zarándi B Penke 2004 Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease J Pept Sci 10 229 248 10.1002/psc.573 15160835 (Pubitemid 38594184)
-
(2004)
Journal of Peptide Science
, vol.10
, Issue.5
, pp. 229-248
-
-
Verdier, Y.1
Zarandi, M.2
Penke, B.3
-
98
-
-
4043088415
-
The role of beta amyloid in Alzheimer's disease: Still a cause of everything or the only one who got caught?
-
DOI 10.1016/j.phrs.2003.12.028, PII S104366180400091X
-
G Verdile S Fuller CS Atwood SM Laws SE Gandy RN Martins 2004 The role of beta amyloid in Alzheimer's disease: still a cause of everything or the only one who got caught? Pharmacol Res 50 397 409 10.1016/j.phrs.2003.12.028 15304237 (Pubitemid 39078531)
-
(2004)
Pharmacological Research
, vol.50
, Issue.4
, pp. 397-409
-
-
Verdile, G.1
Fuller, S.2
Atwood, C.S.3
Laws, S.M.4
Gandy, S.E.5
Martins, R.N.6
-
99
-
-
34248190279
-
Aβ oligomers - A decade of discovery
-
DOI 10.1111/j.1471-4159.2006.04426.x
-
DM Walshe DJ Selkoe 2007 Aβ oligomers a decade of discovery J Neurochem 101 1172 1184 10.1111/j.1471-4159.2006.04426.x (Pubitemid 46718812)
-
(2007)
Journal of Neurochemistry
, vol.101
, Issue.5
, pp. 1172-1184
-
-
Walsh, D.M.1
Selkoe, D.J.2
-
100
-
-
0034609516
-
The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain
-
10.1021/bi001048s 10978169
-
DM Walsh BP Tseng RE Rydel MB Podlisny DJ Selkoe 2000 The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain Biochemistry 39 10831 10839 10.1021/bi001048s 10978169
-
(2000)
Biochemistry
, vol.39
, pp. 10831-10839
-
-
Walsh, D.M.1
Tseng, B.P.2
Rydel, R.E.3
Podlisny, M.B.4
Selkoe, D.J.5
-
101
-
-
14944378094
-
Certain inhibitors of synthetic amyloid β-peptide (Aβ) fibrillogenesis block oligomerization of natural Aβ and thereby rescue long-term potentiation
-
DOI 10.1523/JNEUROSCI.4391-04.2005
-
DM Walsh M Townsend MB Podlisny GM Shankar JV Fadeeva OE Agnaf DM Hartley DJ Selkoe 2005 Certain inhibitors of sy thetic amyloid beta-peptide (Abeta) fibrillogenesis block oligomerization of natural Abeta and thereby rescue long-term potentiation J Neurosci 25 2455 2462 10.1523/JNEUROSCI.4391-04.2005 15758153 (Pubitemid 40365155)
-
(2005)
Journal of Neuroscience
, vol.25
, Issue.10
, pp. 2455-2462
-
-
Walsh, D.M.1
Townsend, M.2
Podlisny, M.B.3
Shankar, G.M.4
Fadeeva, J.V.5
El Agnaf, O.6
Hartley, D.M.7
Selkoe, D.J.8
-
102
-
-
0035829592
-
A subset of NSAIDs lower amyloidogenic Aβ42 independently of cyclooxygenase activity
-
DOI 10.1038/35102591
-
S Weggen JL Eriksen P Das SA Sagi R Wang CU Pietrzik KA Findlay TE Smith MP Murphy T Bulter DE Kang N Marquez-Sterling TE Golde EH Koo 2001 A subset of NSAIDs lower amyloidogenic Abeta42 independently of cyclooxygenase activity Nature 414 212 216 10.1038/35102591 11700559 (Pubitemid 33051236)
-
(2001)
Nature
, vol.414
, Issue.6860
, pp. 212-216
-
-
Weggen, S.1
Eriksen, J.L.2
Das, P.3
Sagi, S.A.4
Wang, R.5
Pietrzik, C.U.6
Findlay, K.A.7
Smith, T.E.8
Murphy, M.P.9
Bulter, T.10
Kang, D.E.11
Marquez-Sterling, N.12
Golde, T.E.13
Koo, E.H.14
-
103
-
-
33646384419
-
Immunology and immunotherapy of Alzheimer's disease
-
10.1038/nri1843 16639431
-
HL Weiner D Frenkel 2006 Immunology and immunotherapy of Alzheimer's disease Nat Rev Immunol 6 404 416 10.1038/nri1843 16639431
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 404-416
-
-
Weiner, H.L.1
Frenkel, D.2
-
104
-
-
0030049032
-
Damage to DNA by reactive oxygenand nitrogen species: Role in inflammatory disease and progression to cancer
-
8546679
-
H Wiseman B Halliwell 1996 Damage to DNA by reactive oxygenand nitrogen species: role in inflammatory disease and progression to cancer Biochem J 313 17 29 8546679
-
(1996)
Biochem J
, vol.313
, pp. 17-29
-
-
Wiseman, H.1
Halliwell, B.2
-
105
-
-
0031461082
-
Biology of Aβ amyloid in Alzheimer's disease
-
DOI 10.1006/nbdi.1997.0147
-
T Wisniewski J Ghiso B Frangione 1997 Biology of Aβ amyloid in Alzheimer's disease Neurobiol Dis 4 313 328 10.1006/nbdi.1997.0147 9440120 (Pubitemid 28018660)
-
(1997)
Neurobiology of Disease
, vol.4
, Issue.5
, pp. 313-328
-
-
Wisniewski, T.1
Ghiso, J.2
Frangione, B.3
-
106
-
-
20044370990
-
Curcumin inhibits formation of amyloid β oligomers and fibrils, binds plaques, and reduces amyloid in vivo
-
DOI 10.1074/jbc.M404751200
-
F Yang GP Lim AN Begum OJ Ubeda MR Simmons SS Ambegaokar PP Chen R Kayed CG Glabe SA Frautschy GM Cole 2005 Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo J Biol Chem 280 5892 5901 10.1074/jbc.M404751200 15590663 (Pubitemid 40280072)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.7
, pp. 5892-5901
-
-
Yang, F.1
Lim, G.P.2
Begum, A.N.3
Ubeda, O.J.4
Simmons, M.R.5
Ambegaokar, S.S.6
Chen, P.7
Kayed, R.8
Glabe, C.G.9
Frautschy, S.A.10
Cole, G.M.11
-
107
-
-
0035910374
-
The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from β-amyloid-induced cell death by inhibiting the formation of β-amyloid-derived diffusible neurotoxic ligands
-
DOI 10.1016/S0006-8993(00)03131-0, PII S0006899300031310
-
Z Yao K Drieu V Papadopoulos 2001 The Ginkgo biloba extract EGb 761 rescues the PC12 neuronal cells from beta-amyloid-induced cell death by inhibiting the formation of beta-amyloid-derived diffusible neurotoxic ligands Brain Res 889 181 190 10.1016/S0006-8993(00)03131-0 11166702 (Pubitemid 32146280)
-
(2001)
Brain Research
, vol.889
, Issue.1-2
, pp. 181-190
-
-
Yao, Z.-X.1
Drieu, K.2
Papadopoulos, V.3
-
108
-
-
34548179335
-
γ-secretase substrate concentration modulates the Aβ42/Aβ40 ratio: Implications for Alzheimer disease
-
DOI 10.1074/jbc.M704601200
-
YI Yin B Bassit L Zhu X Yang C Wang YM Li 2007 Alzheimer's disease: Mental plaque removal J Biol Chem 28 23639 23644 10.1074/jbc.M704601200 (Pubitemid 47311934)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.32
, pp. 23639-23644
-
-
Ye, I.Y.1
Bassit, B.2
Zhu, L.3
Yang, X.4
Wang, C.5
Li, Y.-M.6
-
109
-
-
34548179335
-
γ-secretase substrate concentration modulates the Aβ42/Aβ40 ratio: Implications for Alzheimer disease
-
DOI 10.1074/jbc.M704601200
-
YI Yin B Bassit L Zhu X Yang C Wang YM Li 2007 γ-Secretase substrate Concentration Modulates the Abeta42/Abeta40 Ratio: implications for Alzheimer's disease J Biol Chem 28 23639 23644 10.1074 jbc.M704601200 (Pubitemid 47311934)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.32
, pp. 23639-23644
-
-
Ye, I.Y.1
Bassit, B.2
Zhu, L.3
Yang, X.4
Wang, C.5
Li, Y.-M.6
-
110
-
-
16544373763
-
Gossypin protects primary cultured rat cortical cells from oxidative stress- and β-amyloid-induced toxicity
-
KH Yoon J Lee J Cho 2004 Gossypin protects primary cultured rat cortical cells from oxidative stress- and beta-amyloid-induced toxicity Arch Pharm Res 27 454 459 10.1007/BF02980089 15180313 (Pubitemid 43073744)
-
(2004)
Archives of Pharmacal Research
, vol.27
, Issue.4
, pp. 454-459
-
-
Yoon, I.1
Kwang, H.L.2
Cho, J.3
-
111
-
-
0041589063
-
Melatonin prevents free radical formation due to the interaction between β-amyloid peptides and metal ions [Al(III), Zn(II), Cu(II), Mn(II), Fe(II)]
-
DOI 10.1034/j.1600-079X.2003.00058.x
-
Zatta P, Tognon G, Carampin P (2003) Melatonin prevents free radical formation due to the interaction between beta-amyloid peptides and metal ions. J Pineal Res 35:98-103. Al(III), Zn(II), Cu(II), Mn(II), Fe(II). doi: 10.1034/j.1600-079X.2003.00058.x (Pubitemid 36960348)
-
(2003)
Journal of Pineal Research
, vol.35
, Issue.2
, pp. 98-103
-
-
Zatta, P.1
Tognon, G.2
Carampin, P.3
-
112
-
-
0024652076
-
Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals
-
2472207
-
BL Zhao X Li RG He SJ Cheng WJ Xin 1989 Scavenging effect of extracts of green tea and natural antioxidants on active oxygen radicals Cell Biophys 14 175 185 2472207
-
(1989)
Cell Biophys
, vol.14
, pp. 175-185
-
-
Zhao, B.L.1
Li, X.2
He, R.G.3
Cheng, S.J.4
Xin, W.J.5
-
113
-
-
10044283223
-
Mitochondrial failures in Alzheimer's disease
-
10.1177/153331750401900611 15633943
-
X Zhu MA Smith G Perry G Aliev 2004 Mitochondrial failures in Alzheimer's disease Am J Alzheimers Dis Other Demen 19 345 352 10.1177/153331750401900611 15633943
-
(2004)
Am J Alzheimers Dis Other Demen
, vol.19
, pp. 345-352
-
-
Zhu, X.1
Smith, M.A.2
Perry, G.3
Aliev, G.4
|