Amyloid neurotoxicity is attenuated by metallothionein: Dual mechanisms at work

Journal of Neurochemistry

Volumn 121, Issue 5, 2012, Pages 751-762

  Kim, Jong Heon ^a   Nam, Young Pyo ^a   Jeon, Sang Min ^a   Han, Hyung Soo ^a   Suk, Kyoungho ^a  

^a Kyungpook National University School of Medicine   (South Korea)

Author keywords

Alzheimer's disease; beta amyloid; glia; metallothionein; neurodegenerative disease; neuroinflammation

Indexed keywords

ALPHA TOCOPHEROL; METALLOTHIONEIN; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; RECOMBINANT METALLOTHIONEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CELL; BRAIN REGION; CELL DEATH; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; HUMAN; MALE; MICROGLIA; MOUSE; NEUROBLASTOMA CELL; NEUROPROTECTION; NEUROTOXICITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; UPREGULATION;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; DISEASE MODELS, ANIMAL; DNA FRAGMENTATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; METALLOTHIONEIN; MICE; MICE, TRANSGENIC; MICROGLIA; OXIDATIVE STRESS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

MUS MUSCULUS;

EID: 84860513149     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07725.x     Document Type: Article

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