A family knockout of all four Drosophila metallothioneins reveals a central role in copper homeostasis and detoxification

Molecular and Cellular Biology

Volumn 26, Issue 6, 2006, Pages 2286-2296

  Egli, Dieter ^a   Yepiskoposyan, Hasmik ^a   Selvaraj, Anand ^a   Balamurugan, Kuppusamy ^a   Rajaram, Rama ^a   Simons, Andreas ^b   Multhaup, Gerd ^b   Mettler, Simone ^a   Vardanyan, Alla ^a   Georgiev, Oleg ^a   Schaffner, Walter ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CADMIUM; COPPER; CYSTEINE; HEAVY METAL; MERCURY; METAL RESPONSIVE TRANSCRIPTION FACTOR 1; METALLOTHIONEIN; MUTANT PROTEIN; REGULATOR PROTEIN; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG; ZINC;

ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; COMPLEX FORMATION; CONTROLLED STUDY; DETOXIFICATION; DROSOPHILA MELANOGASTER; GASTROINTESTINAL TRACT; GENE; GENE DISRUPTION; GENE EXPRESSION REGULATION; GENE INDUCTION; GENE TARGETING; LARVA; LIFESPAN; LUMINESCENCE; METAL BINDING; MIDGUT; MTNA GENE; MTNB GENE; MTNC GENE; MTND GENE; MULTIGENE FAMILY; NEGATIVE FEEDBACK; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FAMILY; PROTEIN PROTEIN INTERACTION; REPORTER GENE; TISSUE SPECIFICITY;

AGING; ANIMALS; ANIMALS, GENETICALLY MODIFIED; CADMIUM; COPPER; DNA-BINDING PROTEINS; DROSOPHILA MELANOGASTER; DROSOPHILA PROTEINS; FEMALE; GENE EXPRESSION REGULATION; HOMEOSTASIS; LUMINESCENCE; MALE; MERCURY; METABOLIC DETOXICATION, DRUG; METALLOTHIONEIN; MULTIGENE FAMILY; RECOMBINATION, GENETIC; RESPONSE ELEMENTS; TRANSCRIPTION FACTORS;

ANIMALIA; DROSOPHILA MELANOGASTER;

EID: 33644780954     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.26.6.2286-2296.2006     Document Type: Article

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