Deficiency of metallothionein-1 and -2 genes shortens the lifespan of the 129/Sv mouse strain

Experimental Gerontology

Volumn 66, Issue , 2015, Pages 21-24

  Kadota, Yoshito ^a   Aki, Yuka ^a,b   Toriuchi, Yuriko ^a   Mizuno, Yuto ^a   Kawakami, Takashige ^a   Sato, Masao ^a   Suzuki, Shinya ^a  

^a TOKUSHIMA BUNRI UNIVERSITY   (Japan)

^b School of Medicine   (Japan)

Author keywords

Aging; Lifespan; Longevity; Metallothionein; Senescence

Indexed keywords

COPPER ZINC SUPEROXIDE DISMUTASE; MANGANESE SUPEROXIDE DISMUTASE; METALLOTHIONEIN I; METALLOTHIONEIN II; PHOSPHOLIPID HYDROPEROXIDE GLUTATHIONE PEROXIDASE; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; THIOREDOXIN REDUCTASE; METALLOTHIONEIN; METALLOTHIONEIN-1, MOUSE; MT2 PROTEIN, MOUSE; ZINC;

129 MOUSE; ADULT; AGING; ANIMAL EXPERIMENT; ARTICLE; CLINICAL FEATURE; CONTROLLED STUDY; FEMALE; GENE DELETION; GENE FUNCTION; KNOCKOUT MOUSE; LIFESPAN; LONGEVITY; MALE; MOUSE; MT1 GENE; MT2 GENE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FUNCTION; SENESCENCE; SEX DIFFERENCE; SURVIVAL RATE; WEIGHT REDUCTION; WILD TYPE MOUSE; ANIMAL; GENETICS; METABOLISM; MOTOR ACTIVITY; PHYSIOLOGY;

MAMMALIA; MUS;

ANIMALS; FEMALE; LONGEVITY; MALE; METALLOTHIONEIN; MICE; MICE, 129 STRAIN; MICE, KNOCKOUT; MOTOR ACTIVITY; WEIGHT LOSS; ZINC;

EID: 84928038777     PISSN: 05315565     EISSN: 18736815     Source Type: Journal    
DOI: 10.1016/j.exger.2015.04.007     Document Type: Article

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