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Volumn 66, Issue 5, 2016, Pages 245-259

The origin and future of oxidative stress pathology: From the recognition of carcinogenesis as an iron addiction with ferroptosis-resistance to non-thermal plasma therapy

Author keywords

Carcinogenesis; Free radicals; Iron; Monoclonal antibody; Oxidative stress

Indexed keywords

4 HYDROXYNONENAL; 8 HYDROXYDEOXYGUANOSINE; ASBESTOS; CHRYSOTILE; IRON; MULTI WALLED NANOTUBE; NITRILOTRIACETATE IRON; REACTIVE OXYGEN METABOLITE;

EID: 84959509745     PISSN: 13205463     EISSN: 14401827     Source Type: Journal    
DOI: 10.1111/pin.12396     Document Type: Review
Times cited : (99)

References (150)
  • 2
    • 84894261996 scopus 로고    scopus 로고
    • The rise of oxygen in Earth/'s early ocean and atmosphere
    • Lyons TW, Reinhard CT, Planavsky NJ. The rise of oxygen in Earth/'s early ocean and atmosphere. Nature 2014; 506: 307-15.
    • (2014) Nature , vol.506 , pp. 307-315
    • Lyons, T.W.1    Reinhard, C.T.2    Planavsky, N.J.3
  • 3
    • 0027387472 scopus 로고
    • Rare earth element systematics of the chemically precipitated component in Early Precambrian iron formations and the evolution of the terrestrial atmosphere-hydrosphere-lithosphere system
    • Bau M, Möller P. Rare earth element systematics of the chemically precipitated component in Early Precambrian iron formations and the evolution of the terrestrial atmosphere-hydrosphere-lithosphere system. Geochim Cosmochim Acta 1993; 57: 2239-49.
    • (1993) Geochim Cosmochim Acta , vol.57 , pp. 2239-2249
    • Bau, M.1    Möller, P.2
  • 5
    • 0018505518 scopus 로고
    • Energy systems-the broader context
    • Marchetti C Energy systems-the broader context. Technol Forecast Soc 1979; 14: 191-203.
    • (1979) Technol Forecast Soc , vol.14 , pp. 191-203
    • Marchetti, C.1
  • 7
    • 84859932436 scopus 로고    scopus 로고
    • Studies of the mortality of atomic bomb survivors, report 14, 1950-2003: an overview of cancer and noncancer diseases
    • Ozasa K, Shimizu Y, Suyama A et al. Studies of the mortality of atomic bomb survivors, report 14, 1950-2003: an overview of cancer and noncancer diseases. Radiat Res 2011; 177: 229-43.
    • (2011) Radiat Res , vol.177 , pp. 229-243
    • Ozasa, K.1    Shimizu, Y.2    Suyama, A.3
  • 8
    • 77049308856 scopus 로고
    • Aging: a theory based on free radical and radiation chemistry
    • Harman D Aging: a theory based on free radical and radiation chemistry. J Gerontol 1956; 11: 298-300.
    • (1956) J Gerontol , vol.11 , pp. 298-300
    • Harman, D.1
  • 9
    • 0014691242 scopus 로고
    • Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein)
    • McCord JM, Fridovich I. Superoxide dismutase: an enzymatic function for erythrocuprein (hemocuprein). J Biol Chem 1969; 244: 6049-55.
    • (1969) J Biol Chem , vol.244 , pp. 6049-6055
    • McCord, J.M.1    Fridovich, I.2
  • 10
  • 11
    • 84920903716 scopus 로고    scopus 로고
    • Oxidative stress: A concept in redox biology and medicine
    • Sies H Oxidative stress: A concept in redox biology and medicine. Redox Biol 2015; 4: 180-3.
    • (2015) Redox Biol , vol.4 , pp. 180-183
    • Sies, H.1
  • 12
    • 0022294173 scopus 로고
    • Oxidative stress: excited oxygen species and enzyme activity
    • Cadenas E, Sies H. Oxidative stress: excited oxygen species and enzyme activity. Adv Enzyme Regul 1985; 23: 217-37.
    • (1985) Adv Enzyme Regul , vol.23 , pp. 217-237
    • Cadenas, E.1    Sies, H.2
  • 13
    • 0028918334 scopus 로고
    • Superoxide and hydrogen peroxide in relation to mammalian cell proliferation
    • Burdon RH. Superoxide and hydrogen peroxide in relation to mammalian cell proliferation. Free Radic Biol Med 1995; 18: 775-94.
    • (1995) Free Radic Biol Med , vol.18 , pp. 775-794
    • Burdon, R.H.1
  • 14
    • 84897444272 scopus 로고    scopus 로고
    • 2 generation: redox signaling and oxidative stress
    • 2 generation: redox signaling and oxidative stress. J Biol Chem 2014; 289: 8735-41.
    • (2014) J Biol Chem , vol.289 , pp. 8735-8741
    • Sies, H.1
  • 15
    • 0029932034 scopus 로고    scopus 로고
    • Iron-induced carcinogenesis: the role of redox regulation
    • Toyokuni S. Iron-induced carcinogenesis: the role of redox regulation. Free Radic Biol Med 1996; 20: 553-66.
    • (1996) Free Radic Biol Med , vol.20 , pp. 553-566
    • Toyokuni, S.1
  • 16
    • 0036381371 scopus 로고    scopus 로고
    • Iron and carcinogenesis: from Fenton reaction to target genes
    • Toyokuni S. Iron and carcinogenesis: from Fenton reaction to target genes. Redox Rep 2002; 7: 189-97.
    • (2002) Redox Rep , vol.7 , pp. 189-197
    • Toyokuni, S.1
  • 17
    • 0022460947 scopus 로고
    • The radiation chemistry of the purine bases within DNA and related model compounds
    • Simic MG, Grossman L, Upton AC, eds. New York: Plenum
    • Cadet J, Berger M, Shaw A. The radiation chemistry of the purine bases within DNA and related model compounds. In: Simic MG, Grossman L, Upton AC, eds. Mechanisms of DNA Damage and Repair. New York: Plenum, 1986; 69-74.
    • (1986) Mechanisms of DNA Damage and Repair , pp. 69-74
    • Cadet, J.1    Berger, M.2    Shaw, A.3
  • 18
    • 0026599410 scopus 로고
    • Measurement of radiation-induced damage to DNA at the molecular level
    • Dizdaroglu M. Measurement of radiation-induced damage to DNA at the molecular level. Int J Radiat Biol 1992; 61: 175-83.
    • (1992) Int J Radiat Biol , vol.61 , pp. 175-183
    • Dizdaroglu, M.1
  • 19
    • 84919629589 scopus 로고    scopus 로고
    • Moving free radical and redox biology ahead in the next decade (s)
    • Buettner GR. Moving free radical and redox biology ahead in the next decade (s). Free Radic Biol Med 2015; 78: 236-8.
    • (2015) Free Radic Biol Med , vol.78 , pp. 236-238
    • Buettner, G.R.1
  • 20
    • 0024464691 scopus 로고
    • Lycopene as the most efficient biological carotenoid singlet oxygen quencher
    • Di Mascio P, Kaiser S, Sies H. Lycopene as the most efficient biological carotenoid singlet oxygen quencher. Arch Biochem Biophys 1989; 274: 532-8.
    • (1989) Arch Biochem Biophys , vol.274 , pp. 532-538
    • Di Mascio, P.1    Kaiser, S.2    Sies, H.3
  • 21
    • 0033041916 scopus 로고    scopus 로고
    • Reactive oxygen species-induced molecular damage and its applicaton in pathology
    • Toyokuni S. Reactive oxygen species-induced molecular damage and its applicaton in pathology. Pathol Int 1999; 49: 91-102.
    • (1999) Pathol Int , vol.49 , pp. 91-102
    • Toyokuni, S.1
  • 22
    • 0026485192 scopus 로고
    • Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase
    • Ischiropoulos H, Zhu L, Chen J et al. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch Biochem Biophys 1992; 298: 431-7.
    • (1992) Arch Biochem Biophys , vol.298 , pp. 431-437
    • Ischiropoulos, H.1    Zhu, L.2    Chen, J.3
  • 23
    • 0026606054 scopus 로고
    • Modification of histidine residues in proteins by reaction with 4- hydroxynonenal
    • Uchida K, Stadtman ER. Modification of histidine residues in proteins by reaction with 4- hydroxynonenal. Proc Natl Acad Sci U S A 1992; 89: 4544-8.
    • (1992) Proc Natl Acad Sci U S A , vol.89 , pp. 4544-4548
    • Uchida, K.1    Stadtman, E.R.2
  • 24
    • 0027947380 scopus 로고
    • Chemical determination of oxidative DNA damage by gas chromatography- mass spectrometry
    • Dizdaroglu M Chemical determination of oxidative DNA damage by gas chromatography- mass spectrometry. Methods Enzymol 1994; 234: 3-16.
    • (1994) Methods Enzymol , vol.234 , pp. 3-16
    • Dizdaroglu, M.1
  • 25
    • 34447095535 scopus 로고    scopus 로고
    • Pathological investigation of oxidative stress in the post-genomic era
    • Toyokuni S, Akatsuka S. Pathological investigation of oxidative stress in the post-genomic era. Pathol Int 2007; 57: 461-73.
    • (2007) Pathol Int , vol.57 , pp. 461-473
    • Toyokuni, S.1    Akatsuka, S.2
  • 26
    • 84876719805 scopus 로고    scopus 로고
    • A highly selective turn-on fluorescent probe fro iron(II) to visualize labile iron in living cells
    • Hirayama T, Okuda K, Nagasawa H. A highly selective turn-on fluorescent probe fro iron(II) to visualize labile iron in living cells. Chem Sci 2013; 4: 1250-6.
    • (2013) Chem Sci , vol.4 , pp. 1250-1256
    • Hirayama, T.1    Okuda, K.2    Nagasawa, H.3
  • 27
    • 84906061681 scopus 로고    scopus 로고
    • Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model
    • Mukaide T, Hattori Y, Misawa N et al. Histological detection of catalytic ferrous iron with the selective turn-on fluorescent probe RhoNox-1 in a Fenton reaction-based rat renal carcinogenesis model. Free Radic Res 2014; 48: 990-5.
    • (2014) Free Radic Res , vol.48 , pp. 990-995
    • Mukaide, T.1    Hattori, Y.2    Misawa, N.3
  • 28
    • 18544384019 scopus 로고
    • Oxidation of tartaric acid in presence of iron
    • Fenton HJH. Oxidation of tartaric acid in presence of iron. J Chem Soc 1894; 65: 899-910.
    • (1894) J Chem Soc , vol.65 , pp. 899-910
    • Fenton, H.J.H.1
  • 29
    • 0032583570 scopus 로고    scopus 로고
    • Glutathione and Catalase Provide Overlapping Defenses for Protection against Hydrogen Peroxide in the YeastSaccharomyces cerevisiae
    • Grant CM, Perrone G, Dawes IW. Glutathione and Catalase Provide Overlapping Defenses for Protection against Hydrogen Peroxide in the YeastSaccharomyces cerevisiae. Biochem Biophys Res Commun 1998; 253: 893-8.
    • (1998) Biochem Biophys Res Commun , vol.253 , pp. 893-898
    • Grant, C.M.1    Perrone, G.2    Dawes, I.W.3
  • 30
    • 0015880169 scopus 로고
    • Glutathione peroxidase: a selenoenzyme
    • Flohe L, Günzler WA, Schock HH. Glutathione peroxidase: a selenoenzyme. FEBS Lett 1973; 32: 132-4.
    • (1973) FEBS Lett , vol.32 , pp. 132-134
    • Flohe, L.1    Günzler, W.A.2    Schock, H.H.3
  • 31
    • 19444375216 scopus 로고    scopus 로고
    • Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling
    • Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 2005; 38: 1543-52.
    • (2005) Free Radic Biol Med , vol.38 , pp. 1543-1552
    • Rhee, S.G.1    Chae, H.Z.2    Kim, K.3
  • 32
    • 84863463209 scopus 로고    scopus 로고
    • Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression
    • Jeong W, Bae SH, Toledano MB, Rhee SG. Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression. Free Radic Biol Med 2012; 53: 447-56.
    • (2012) Free Radic Biol Med , vol.53 , pp. 447-456
    • Jeong, W.1    Bae, S.H.2    Toledano, M.B.3    Rhee, S.G.4
  • 34
    • 11144221439 scopus 로고    scopus 로고
    • Widespread sulfenic acid formation in tissues in response to hydrogen peroxide
    • Saurin AT, Neubert H, Brennan JP, Eaton P. Widespread sulfenic acid formation in tissues in response to hydrogen peroxide. Proc Natl Acad Sci U S A 2004; 101: 17982-7.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 17982-17987
    • Saurin, A.T.1    Neubert, H.2    Brennan, J.P.3    Eaton, P.4
  • 35
    • 0242668688 scopus 로고    scopus 로고
    • Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation
    • Woo HA, Chae HZ, Hwang SC et al. Reversing the inactivation of peroxiredoxins caused by cysteine sulfinic acid formation. Science 2003; 300: 653-6.
    • (2003) Science , vol.300 , pp. 653-656
    • Woo, H.A.1    Chae, H.Z.2    Hwang, S.C.3
  • 36
    • 3843064487 scopus 로고    scopus 로고
    • The sulfinic acid switch in proteins
    • Jacob C, Holme AL, Fry FH. The sulfinic acid switch in proteins. Org Biomol Chem 2004; 2: 1953-6.
    • (2004) Org Biomol Chem , vol.2 , pp. 1953-1956
    • Jacob, C.1    Holme, A.L.2    Fry, F.H.3
  • 37
    • 84892366219 scopus 로고    scopus 로고
    • The thioredoxin antioxidant system
    • Lu J, Holmgren A. The thioredoxin antioxidant system. Free Radic Biol Med 2014; 66: 75-87.
    • (2014) Free Radic Biol Med , vol.66 , pp. 75-87
    • Lu, J.1    Holmgren, A.2
  • 38
    • 0032827002 scopus 로고    scopus 로고
    • Regulatory mechanisms of cellular response to oxidative stress
    • Itoh K, Ishii T, Wakabayashi N, Yamamoto M. Regulatory mechanisms of cellular response to oxidative stress. Free Radic Res 1999; 31: 319-24.
    • (1999) Free Radic Res , vol.31 , pp. 319-324
    • Itoh, K.1    Ishii, T.2    Wakabayashi, N.3    Yamamoto, M.4
  • 39
    • 0032953192 scopus 로고    scopus 로고
    • Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain
    • Itoh K, Wakabayashi N, Katoh Y et al. Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain. Genes Dev 1999; 13: 76-86.
    • (1999) Genes Dev , vol.13 , pp. 76-86
    • Itoh, K.1    Wakabayashi, N.2    Katoh, Y.3
  • 40
    • 84878572136 scopus 로고    scopus 로고
    • Toward clinical application of the Keap1-Nrf2 pathway
    • Suzuki T, Motohashi H, Yamamoto M. Toward clinical application of the Keap1-Nrf2 pathway. Trends Pharmacol Sci 2013; 34: 340-6.
    • (2013) Trends Pharmacol Sci , vol.34 , pp. 340-346
    • Suzuki, T.1    Motohashi, H.2    Yamamoto, M.3
  • 41
    • 40449107193 scopus 로고    scopus 로고
    • Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth
    • Ohta T, Iijima K, Miyamoto M et al. Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth. Cancer Res 2008; 68: 1303-9.
    • (2008) Cancer Res , vol.68 , pp. 1303-1309
    • Ohta, T.1    Iijima, K.2    Miyamoto, M.3
  • 42
    • 84864348569 scopus 로고    scopus 로고
    • NRF2 and cancer: the good, the bad and the importance of context
    • Sporn MB, Liby KT. NRF2 and cancer: the good, the bad and the importance of context. Nat Rev Cancer 2012; 12: 564-71.
    • (2012) Nat Rev Cancer , vol.12 , pp. 564-571
    • Sporn, M.B.1    Liby, K.T.2
  • 43
    • 0028032254 scopus 로고
    • Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines
    • Dypbukt JM, Ankarcrona M, Burkitt M et al. Different prooxidant levels stimulate growth, trigger apoptosis, or produce necrosis of insulin-secreting RINm5F cells. The role of intracellular polyamines. J Biol Chem 1994; 269: 30553-60.
    • (1994) J Biol Chem , vol.269 , pp. 30553-30560
    • Dypbukt, J.M.1    Ankarcrona, M.2    Burkitt, M.3
  • 44
    • 2442667547 scopus 로고    scopus 로고
    • Detection of glyceraldehyde 3-phosphate dehydrogenase messenger RNA using a peptide nucleic acid probe in paraffin-embedded archival specimens
    • Hiroyasu M, Akatsuka S, Shirase T, Toda Y, Hiai H, Toyokuni S. Detection of glyceraldehyde 3-phosphate dehydrogenase messenger RNA using a peptide nucleic acid probe in paraffin-embedded archival specimens. Pathol Int 2004; 54: 251-5.
    • (2004) Pathol Int , vol.54 , pp. 251-255
    • Hiroyasu, M.1    Akatsuka, S.2    Shirase, T.3    Toda, Y.4    Hiai, H.5    Toyokuni, S.6
  • 46
    • 0034896767 scopus 로고    scopus 로고
    • An electron spin resonance study on alkylperoxyl radical in thin-sliced renal tissues from ferric nitrilotriacetate-treated rats: the effect of alpha-tocopherol feeding
    • Toyokuni S, Masumizu T, Ozeki M et al. An electron spin resonance study on alkylperoxyl radical in thin-sliced renal tissues from ferric nitrilotriacetate-treated rats: the effect of alpha-tocopherol feeding. Free Radic Res 2001; 35: 245-55.
    • (2001) Free Radic Res , vol.35 , pp. 245-255
    • Toyokuni, S.1    Masumizu, T.2    Ozeki, M.3
  • 47
    • 0015217866 scopus 로고
    • The kinetics and mechanism of iron (III) exchange between chelates and transferrin IV. The reaction of transferrin with iron (III) nitrilotriacetate
    • Bates GW, Wernicke J. The kinetics and mechanism of iron (III) exchange between chelates and transferrin IV. The reaction of transferrin with iron (III) nitrilotriacetate. J Biol Chem 1971; 246: 3679-85.
    • (1971) J Biol Chem , vol.246 , pp. 3679-3685
    • Bates, G.W.1    Wernicke, J.2
  • 48
    • 0018358875 scopus 로고
    • Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate: a model of experimental hemochromatosis
    • Awai M, Narasaki M, Yamanoi Y, Seno S. Induction of diabetes in animals by parenteral administration of ferric nitrilotriacetate: a model of experimental hemochromatosis. Am J Pathol 1979; 95: 663-74.
    • (1979) Am J Pathol , vol.95 , pp. 663-674
    • Awai, M.1    Narasaki, M.2    Yamanoi, Y.3    Seno, S.4
  • 49
    • 0020402875 scopus 로고
    • Induction of rat renal adenocarcinoma by Fe-nitrilotriacetate (Fe-NTA)
    • Okada S, Midorikawa O. Induction of rat renal adenocarcinoma by Fe-nitrilotriacetate (Fe-NTA). Jpn Arch Intern Med 1982; 29: 485-91.
    • (1982) Jpn Arch Intern Med , vol.29 , pp. 485-491
    • Okada, S.1    Midorikawa, O.2
  • 50
    • 0022634070 scopus 로고
    • Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum- nitrilotriacetate complexes in rats
    • Ebina Y, Okada S, Hamazaki S, Ogino F, Li JL, Midorikawa O. Nephrotoxicity and renal cell carcinoma after use of iron- and aluminum- nitrilotriacetate complexes in rats. J Natl Cancer Inst 1986; 76: 107-13.
    • (1986) J Natl Cancer Inst , vol.76 , pp. 107-113
    • Ebina, Y.1    Okada, S.2    Hamazaki, S.3    Ogino, F.4    Li, J.L.5    Midorikawa, O.6
  • 51
    • 0023091969 scopus 로고
    • Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate
    • Li JL, Okada S, Hamazaki S, Ebina Y, Midorikawa O. Subacute nephrotoxicity and induction of renal cell carcinoma in mice treated with ferric nitrilotriacetate. Cancer Res 1987; 47: 1867-9.
    • (1987) Cancer Res , vol.47 , pp. 1867-1869
    • Li, J.L.1    Okada, S.2    Hamazaki, S.3    Ebina, Y.4    Midorikawa, O.5
  • 52
    • 0021905430 scopus 로고
    • Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats
    • Hamazaki S, Okada S, Ebina Y, Midorikawa O. Acute renal failure and glucosuria induced by ferric nitrilotriacetate in rats. Toxicol Appl Pharmacol 1985; 77: 267-74.
    • (1985) Toxicol Appl Pharmacol , vol.77 , pp. 267-274
    • Hamazaki, S.1    Okada, S.2    Ebina, Y.3    Midorikawa, O.4
  • 53
    • 0022536732 scopus 로고
    • Nephrotoxicity of ferric nitrilotriacetate: an electron-microscopic and metabolic study
    • Hamazaki S, Okada S, Ebina Y, Fujioka M, Midorikawa O. Nephrotoxicity of ferric nitrilotriacetate: an electron-microscopic and metabolic study. Am J Pathol 1986; 123: 343-50.
    • (1986) Am J Pathol , vol.123 , pp. 343-350
    • Hamazaki, S.1    Okada, S.2    Ebina, Y.3    Fujioka, M.4    Midorikawa, O.5
  • 54
    • 0023616845 scopus 로고
    • Nephrotoxicity and its prevention by vitamin E on ferric nitrilotriacetate-promoted lipid peroxidation
    • Okada S, Hamazaki S, Ebina Y, Li J-L, Midorikawa O. Nephrotoxicity and its prevention by vitamin E on ferric nitrilotriacetate-promoted lipid peroxidation. Biochim Biophys Acta 1987; 922: 28-33.
    • (1987) Biochim Biophys Acta , vol.922 , pp. 28-33
    • Okada, S.1    Hamazaki, S.2    Ebina, Y.3    Li, J.-L.4    Midorikawa, O.5
  • 55
    • 0023501904 scopus 로고
    • Histochemical detection of lipid peroxidation in the liver of bromobenzene-poisoned mice
    • Pompella A, Maellaro E, Casini AF, Comporti M. Histochemical detection of lipid peroxidation in the liver of bromobenzene-poisoned mice. Am J Pathol 1987; 129: 295-301.
    • (1987) Am J Pathol , vol.129 , pp. 295-301
    • Pompella, A.1    Maellaro, E.2    Casini, A.F.3    Comporti, M.4
  • 56
    • 0023684740 scopus 로고
    • 4-Hydroxynonenal and other lipid peroxidation products are formed in mouse liver following intoxication with allyl alcohol
    • Pompella A, Romani A, Fulceri R, Benedetti A, Comporti M. 4-Hydroxynonenal and other lipid peroxidation products are formed in mouse liver following intoxication with allyl alcohol. Biochim Biophys Acta 1988; 961: 293-8.
    • (1988) Biochim Biophys Acta , vol.961 , pp. 293-298
    • Pompella, A.1    Romani, A.2    Fulceri, R.3    Benedetti, A.4    Comporti, M.5
  • 57
    • 0025102850 scopus 로고
    • Combined histochemical and biochemical analysis of sex hormone dependence of ferric nitrilotriacetate-induced renal lipid peroxidation in ddY mice
    • Toyokuni S, Okada S, Hamazaki S et al. Combined histochemical and biochemical analysis of sex hormone dependence of ferric nitrilotriacetate-induced renal lipid peroxidation in ddY mice. Cancer Res 1990; 50: 5574-80.
    • (1990) Cancer Res , vol.50 , pp. 5574-5580
    • Toyokuni, S.1    Okada, S.2    Hamazaki, S.3
  • 58
    • 0025752652 scopus 로고
    • Sex differences in the localization and severity of ferric nitrilotriacetate-induced lipid peroxidation in the mouse kidney
    • Okada S, Fukunaga Y, Hamazaki S, Yamada Y, Toyokuni S. Sex differences in the localization and severity of ferric nitrilotriacetate-induced lipid peroxidation in the mouse kidney. Acta Pathol Jpn 1991; 41: 221-6.
    • (1991) Acta Pathol Jpn , vol.41 , pp. 221-226
    • Okada, S.1    Fukunaga, Y.2    Hamazaki, S.3    Yamada, Y.4    Toyokuni, S.5
  • 59
    • 0029999597 scopus 로고    scopus 로고
    • Iron-induced tissue damage and cancer: The role of reactive oxygen free radicals
    • Okada S Iron-induced tissue damage and cancer: The role of reactive oxygen free radicals. Pathol Int 1996; 46: 311-32.
    • (1996) Pathol Int , vol.46 , pp. 311-332
    • Okada, S.1
  • 60
    • 0026795635 scopus 로고
    • Protein oxidation and aging
    • Stadtman ER. Protein oxidation and aging. Science 1992; 257: 1220-4.
    • (1992) Science , vol.257 , pp. 1220-1224
    • Stadtman, E.R.1
  • 62
    • 0028226487 scopus 로고
    • DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate
    • Toyokuni S, Mori T, Dizdaroglu M. DNA base modifications in renal chromatin of Wistar rats treated with a renal carcinogen, ferric nitrilotriacetate. Int J Cancer 1994; 57: 123-8.
    • (1994) Int J Cancer , vol.57 , pp. 123-128
    • Toyokuni, S.1    Mori, T.2    Dizdaroglu, M.3
  • 63
    • 0029124259 scopus 로고
    • Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin
    • Toyokuni S, Mori T, Hiai H, Dizdaroglu M. Treatment of Wistar rats with a renal carcinogen, ferric nitrilotriacetate, causes DNA-protein cross-linking between thymine and tyrosine in their renal chromatin. Int J Cancer 1995; 62: 309-13.
    • (1995) Int J Cancer , vol.62 , pp. 309-313
    • Toyokuni, S.1    Mori, T.2    Hiai, H.3    Dizdaroglu, M.4
  • 65
    • 0028223268 scopus 로고
    • Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate
    • Toyokuni S, Uchida K, Okamoto K, Hattori-Nakakuki Y, Hiai H, Stadtman ER. Formation of 4-hydroxy-2-nonenal-modified proteins in the renal proximal tubules of rats treated with a renal carcinogen, ferric nitrilotriacetate. Proc Natl Acad Sci U S A 1994; 91: 2616-20.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 2616-2620
    • Toyokuni, S.1    Uchida, K.2    Okamoto, K.3    Hattori-Nakakuki, Y.4    Hiai, H.5    Stadtman, E.R.6
  • 66
    • 0030948596 scopus 로고    scopus 로고
    • Quantitative immunohistochemical determination of 8-hydroxy-2′-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model
    • Toyokuni S, Tanaka T, Hattori Y et al. Quantitative immunohistochemical determination of 8-hydroxy-2′-deoxyguanosine by a monoclonal antibody N45.1: its application to ferric nitrilotriacetate-induced renal carcinogenesis model. Lab Invest 1997; 76: 365-74.
    • (1997) Lab Invest , vol.76 , pp. 365-374
    • Toyokuni, S.1    Tanaka, T.2    Hattori, Y.3
  • 67
    • 0028840052 scopus 로고
    • The monoclonal antibody specific for the 4-hydroxy-2-nonenal histidine adduct
    • Toyokuni S, Miyake N, Hiai H et al. The monoclonal antibody specific for the 4-hydroxy-2-nonenal histidine adduct. FEBS Lett 1995; 359: 189-91.
    • (1995) FEBS Lett , vol.359 , pp. 189-191
    • Toyokuni, S.1    Miyake, N.2    Hiai, H.3
  • 68
    • 0032998220 scopus 로고    scopus 로고
    • Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes
    • Ihara Y, Toyokuni S, Uchida K et al. Hyperglycemia causes oxidative stress in pancreatic beta-cells of GK rats, a model of type 2 diabetes. Diabetes 1999; 48: 927-32.
    • (1999) Diabetes , vol.48 , pp. 927-932
    • Ihara, Y.1    Toyokuni, S.2    Uchida, K.3
  • 69
    • 0029827808 scopus 로고    scopus 로고
    • 8-Hydroxy-2′-deoxyguanosine is increased in epidermal cells of hairless mice after chronic UVB exposure
    • Hattori Y, Nishigori C, Tanaka T et al. 8-Hydroxy-2′-deoxyguanosine is increased in epidermal cells of hairless mice after chronic UVB exposure. J Invest Dermatol 1996; 107: 733-7.
    • (1996) J Invest Dermatol , vol.107 , pp. 733-737
    • Hattori, Y.1    Nishigori, C.2    Tanaka, T.3
  • 70
    • 33750631631 scopus 로고    scopus 로고
    • Novel screening method for ultraviolet protection: Combination of a human skin-equivalent model and 8-hydroxy-2′-deoxyguanosine
    • Toyokuni S, Yasui H, Date A et al. Novel screening method for ultraviolet protection: Combination of a human skin-equivalent model and 8-hydroxy-2′-deoxyguanosine. Pathol Int 2006; 56: 760-2.
    • (2006) Pathol Int , vol.56 , pp. 760-762
    • Toyokuni, S.1    Yasui, H.2    Date, A.3
  • 71
    • 0042771971 scopus 로고    scopus 로고
    • The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2′-deoxyguanosine in arsenic-related Bowen's disease
    • Matsui M, Nishigori C, Toyokuni S et al. The role of oxidative DNA damage in human arsenic carcinogenesis: detection of 8-hydroxy-2′-deoxyguanosine in arsenic-related Bowen's disease. J Invest Dermatol 1999; 113: 26-31.
    • (1999) J Invest Dermatol , vol.113 , pp. 26-31
    • Matsui, M.1    Nishigori, C.2    Toyokuni, S.3
  • 72
    • 0030755366 scopus 로고    scopus 로고
    • Cloning and characterization of a mammalian proton-coupled metal-ion transporter
    • Gunshin H, Mackenzie B, Berger U et al. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 1997; 388: 482-8.
    • (1997) Nature , vol.388 , pp. 482-488
    • Gunshin, H.1    Mackenzie, B.2    Berger, U.3
  • 73
    • 58149305448 scopus 로고    scopus 로고
    • Role of iron in carcinogenesis: Cancer as a ferrotoxic disease
    • Toyokuni S Role of iron in carcinogenesis: Cancer as a ferrotoxic disease. Cancer Sci 2009; 100: 9-16.
    • (2009) Cancer Sci , vol.100 , pp. 9-16
    • Toyokuni, S.1
  • 75
    • 0029417257 scopus 로고
    • Low incidence of point mutations in H-, K- and N-ras oncogenes and p53 tumor suppressor gene in renal cell carcinoma and peritoneal mesothelioma of Wistar rats induced by ferric nitrilotriacetate
    • Nishiyama Y, Suwa H, Okamoto K, Fukumoto M, Hiai H, Toyokuni S. Low incidence of point mutations in H-, K- and N-ras oncogenes and p53 tumor suppressor gene in renal cell carcinoma and peritoneal mesothelioma of Wistar rats induced by ferric nitrilotriacetate. Jpn J Cancer Res 1995; 86: 1150-8.
    • (1995) Jpn J Cancer Res , vol.86 , pp. 1150-1158
    • Nishiyama, Y.1    Suwa, H.2    Okamoto, K.3    Fukumoto, M.4    Hiai, H.5    Toyokuni, S.6
  • 76
    • 0033600115 scopus 로고    scopus 로고
    • INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats
    • INK4A tumor suppressor genes in oxystress-induced renal cell carcinoma of rats. Oncogene 1999; 18: 3793-7.
    • (1999) Oncogene , vol.18 , pp. 3793-3797
    • Tanaka, T.1    Iwasa, Y.2    Kondo, S.3    Hiai, H.4    Toyokuni, S.5
  • 77
    • 0030587573 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal cytotoxicity in renal proximal tubular cells: protein modification and redox alteration
    • Fukuda A, Osawa T, Hitomi K, Uchida K. 4-Hydroxy-2-nonenal cytotoxicity in renal proximal tubular cells: protein modification and redox alteration. Arch Biochem Biophys 1996; 333: 419-26.
    • (1996) Arch Biochem Biophys , vol.333 , pp. 419-426
    • Fukuda, A.1    Osawa, T.2    Hitomi, K.3    Uchida, K.4
  • 78
    • 0033151677 scopus 로고    scopus 로고
    • A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein- and hydroxynonenal-modified proteins by epitope-bound casein matrix method
    • Satoh K, Yamada S, Koike Y, et al. A 1-hour enzyme-linked immunosorbent assay for quantitation of acrolein- and hydroxynonenal-modified proteins by epitope-bound casein matrix method. Anal Biochem 1999; 270: 323-8.
    • (1999) Anal Biochem , vol.270 , pp. 323-328
    • Satoh, K.1    Yamada, S.2    Koike, Y.3
  • 79
    • 0033588087 scopus 로고    scopus 로고
    • 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules
    • Okada K, Wangpoengtrakul C, Osawa T, Toyokuni S, Tanaka K, Uchida K. 4-Hydroxy-2-nonenal-mediated impairment of intracellular proteolysis during oxidative stress. Identification of proteasomes as target molecules. J Biol Chem 1999; 274: 23787-93.
    • (1999) J Biol Chem , vol.274 , pp. 23787-23793
    • Okada, K.1    Wangpoengtrakul, C.2    Osawa, T.3    Toyokuni, S.4    Tanaka, K.5    Uchida, K.6
  • 80
    • 0347379870 scopus 로고    scopus 로고
    • Formation of acrolein-derived 2′-deoxyadenosine adduct in an iron-induced carcinogenesis model
    • Kawai Y, Furuhata A, Toyokuni S, Aratani Y, Uchida K. Formation of acrolein-derived 2′-deoxyadenosine adduct in an iron-induced carcinogenesis model. J Biol Chem 2003; 278: 50346-54.
    • (2003) J Biol Chem , vol.278 , pp. 50346-50354
    • Kawai, Y.1    Furuhata, A.2    Toyokuni, S.3    Aratani, Y.4    Uchida, K.5
  • 81
    • 0037799214 scopus 로고    scopus 로고
    • Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterizations of configurational isomers of a 4-hydroxy-2-nonenal-histidine adduct
    • Hashimoto M, Sibata T, Wasada H, Toyokuni S, Uchida K. Structural basis of protein-bound endogenous aldehydes. Chemical and immunochemical characterizations of configurational isomers of a 4-hydroxy-2-nonenal-histidine adduct. J Biol Chem 2003; 278: 5044-51.
    • (2003) J Biol Chem , vol.278 , pp. 5044-5051
    • Hashimoto, M.1    Sibata, T.2    Wasada, H.3    Toyokuni, S.4    Uchida, K.5
  • 83
    • 47049094294 scopus 로고    scopus 로고
    • 2-mediated covalent modification of protein by lipid peroxidation-derived saturated aldehydes
    • 2-mediated covalent modification of protein by lipid peroxidation-derived saturated aldehydes. Chem Res Toxicol 2008; 21: 1261-70.
    • (2008) Chem Res Toxicol , vol.21 , pp. 1261-1270
    • Ishino, K.1    Shibata, T.2    Ishii, T.3
  • 84
    • 0027210123 scopus 로고
    • Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules
    • Okada S, Minamiyama Y, Hamazaki S, Toyokuni S, Sotomatsu A. Glutathione cycle dependency of ferric nitrilotriacetate-induced lipid peroxidation in mouse proximal renal tubules. Arch Biochem Biophys 1993; 301: 138-42.
    • (1993) Arch Biochem Biophys , vol.301 , pp. 138-142
    • Okada, S.1    Minamiyama, Y.2    Hamazaki, S.3    Toyokuni, S.4    Sotomatsu, A.5
  • 85
    • 0026662410 scopus 로고
    • Iron-mediated DNA damage: sensitive detection of DNA strand breakage catalyzed by iron
    • Toyokuni S, Sagripanti JL. Iron-mediated DNA damage: sensitive detection of DNA strand breakage catalyzed by iron. J Inorg Biochem 1992; 47: 241-8.
    • (1992) J Inorg Biochem , vol.47 , pp. 241-248
    • Toyokuni, S.1    Sagripanti, J.L.2
  • 86
    • 0027252463 scopus 로고
    • DNA single- and double-strand breaks produced by ferric nitrilotriacetate in relation to renal tubular carcinogenesis
    • Toyokuni S, Sagripanti J-L. DNA single- and double-strand breaks produced by ferric nitrilotriacetate in relation to renal tubular carcinogenesis. Carcinogenesis 1993; 14: 223-7.
    • (1993) Carcinogenesis , vol.14 , pp. 223-227
    • Toyokuni, S.1    Sagripanti, J.-L.2
  • 87
    • 84865603277 scopus 로고    scopus 로고
    • Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer
    • e43403.
    • Akatsuka S, Yamashita Y, Ohara H, et al. Fenton reaction induced cancer in wild type rats recapitulates genomic alterations observed in human cancer. PLoS One 2012; 7 e43403.
    • (2012) PLoS One , vol.7
    • Akatsuka, S.1    Yamashita, Y.2    Ohara, H.3
  • 88
    • 38349041715 scopus 로고    scopus 로고
    • Chronic oxidative stress causes amplification and overexpresson of ptprz1 protein tyrosine phosphatase to activate b-catenin pathway
    • Liu Y-T, Shang D-G, Akatsuka S et al. Chronic oxidative stress causes amplification and overexpresson of ptprz1 protein tyrosine phosphatase to activate b-catenin pathway. Am J Pathol 2007; 171: 1978-88.
    • (2007) Am J Pathol , vol.171 , pp. 1978-1988
    • Liu, Y.-T.1    Shang, D.-G.2    Akatsuka, S.3
  • 89
    • 0025970835 scopus 로고
    • The Oxford Grid
    • Edwards JH. The Oxford Grid. Ann Hum Genet 1991; 55: 17-31.
    • (1991) Ann Hum Genet , vol.55 , pp. 17-31
    • Edwards, J.H.1
  • 90
    • 78650738524 scopus 로고    scopus 로고
    • Mysterious link between iron overload and CDKN2A/2B
    • Toyokuni S Mysterious link between iron overload and CDKN2A/2B. J Clin Biochem Nutr 2011; 48: 46-9.
    • (2011) J Clin Biochem Nutr , vol.48 , pp. 46-49
    • Toyokuni, S.1
  • 91
    • 33746881767 scopus 로고    scopus 로고
    • What has been learned from the studies of oxidative stress-induced carcinogenesis: Proposal of the concept of oxygenomics
    • Toyokuni S, Akatsuka S. What has been learned from the studies of oxidative stress-induced carcinogenesis: Proposal of the concept of oxygenomics. J Clin Biochem Nutr 2006; 39: 3-10.
    • (2006) J Clin Biochem Nutr , vol.39 , pp. 3-10
    • Toyokuni, S.1    Akatsuka, S.2
  • 92
    • 48849114365 scopus 로고    scopus 로고
    • Molecular mechanisms of oxidative stress-induced carcinogenesis: from epidemiology to oxygenomics
    • Toyokuni S Molecular mechanisms of oxidative stress-induced carcinogenesis: from epidemiology to oxygenomics. IUBMB Life 2008; 60: 441-7.
    • (2008) IUBMB Life , vol.60 , pp. 441-447
    • Toyokuni, S.1
  • 94
    • 0029924049 scopus 로고    scopus 로고
    • Association between 8-hydroxy-2′-deoxyguanosine formation and DNA strand breaks mediated by copper and iron
    • Toyokuni S, Sagripanti J-L. Association between 8-hydroxy-2′-deoxyguanosine formation and DNA strand breaks mediated by copper and iron. Free Radic Biol Med 1996; 20: 859-64.
    • (1996) Free Radic Biol Med , vol.20 , pp. 859-864
    • Toyokuni, S.1    Sagripanti, J.-L.2
  • 95
    • 77956567774 scopus 로고    scopus 로고
    • Genome-scale approaches to investigate oxidative DNA damage
    • Akatsuka S, Toyokuni S. Genome-scale approaches to investigate oxidative DNA damage. J Clin Biochem Nutr 2010; 47: 91-7.
    • (2010) J Clin Biochem Nutr , vol.47 , pp. 91-97
    • Akatsuka, S.1    Toyokuni, S.2
  • 96
    • 33748948995 scopus 로고    scopus 로고
    • Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis
    • Akatsuka S, Aung TT, Dutta KK et al. Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis. Am J Pathol 2006; 169: 1328-42.
    • (2006) Am J Pathol , vol.169 , pp. 1328-1342
    • Akatsuka, S.1    Aung, T.T.2    Dutta, K.K.3
  • 97
    • 0035316574 scopus 로고    scopus 로고
    • Chromosome territories, nuclear architecture and gene regulation in mammalian cells
    • Cremer T, Cremer C. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat Rev Genet 2001; 2: p292-301.
    • (2001) Nat Rev Genet , vol.2 , pp. p292-p301
    • Cremer, T.1    Cremer, C.2
  • 98
    • 0037007044 scopus 로고    scopus 로고
    • Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates
    • Tanabe H, Muller S, Neusser M et al. Evolutionary conservation of chromosome territory arrangements in cell nuclei from higher primates. Proc Natl Acad Sci U S A 2002; 99: 4424-9.
    • (2002) Proc Natl Acad Sci U S A , vol.99 , pp. 4424-4429
    • Tanabe, H.1    Muller, S.2    Neusser, M.3
  • 99
    • 84922476725 scopus 로고    scopus 로고
    • Genome-wide profiling of 8-oxoguanine reveals its association with spatial positioning in nucleus
    • Yoshihara M, Jiang L, Akatsuka S, Suyama M, Toyokuni S. Genome-wide profiling of 8-oxoguanine reveals its association with spatial positioning in nucleus. DNA Res 2014; 21: 603-12.
    • (2014) DNA Res , vol.21 , pp. 603-612
    • Yoshihara, M.1    Jiang, L.2    Akatsuka, S.3    Suyama, M.4    Toyokuni, S.5
  • 100
    • 84861541814 scopus 로고    scopus 로고
    • Ferroptosis: an iron-dependent form of nonapoptotic cell death
    • Dixon SJ, Lemberg KM, Lamprecht MR et al. Ferroptosis: an iron-dependent form of nonapoptotic cell death. Cell 2012; 149: 1060-72.
    • (2012) Cell , vol.149 , pp. 1060-1072
    • Dixon, S.J.1    Lemberg, K.M.2    Lamprecht, M.R.3
  • 101
    • 0020065662 scopus 로고
    • Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides
    • Ursini F, Maiorino M, Valente M, Ferri L, Gregolin C. Purification from pig liver of a protein which protects liposomes and biomembranes from peroxidative degradation and exhibits glutathione peroxidase activity on phosphatidylcholine hydroperoxides. Biochim Biophys Acta 1982; 710: 197-211.
    • (1982) Biochim Biophys Acta , vol.710 , pp. 197-211
    • Ursini, F.1    Maiorino, M.2    Valente, M.3    Ferri, L.4    Gregolin, C.5
  • 102
    • 84892685001 scopus 로고    scopus 로고
    • Regulation of ferroptotic cancer cell death by GPX4
    • Yang WS, SriRamaratnam R, Welsch ME et al. Regulation of ferroptotic cancer cell death by GPX4. Cell 2014; 156: 317-31.
    • (2014) Cell , vol.156 , pp. 317-331
    • Yang, W.S.1    SriRamaratnam, R.2    Welsch, M.E.3
  • 103
    • 0037438730 scopus 로고    scopus 로고
    • Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
    • Imai H, Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med 2003; 34: 145-69.
    • (2003) Free Radic Biol Med , vol.34 , pp. 145-169
    • Imai, H.1    Nakagawa, Y.2
  • 104
    • 84925286831 scopus 로고    scopus 로고
    • Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
    • Angeli JPF, Schneider M, Proneth B et al. Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice. Nat Cell Biol 2014; 16: 1180-91.
    • (2014) Nat Cell Biol , vol.16 , pp. 1180-1191
    • Angeli, J.P.F.1    Schneider, M.2    Proneth, B.3
  • 105
    • 0028169262 scopus 로고
    • Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal- modified proteins in human renal-cell carcinoma
    • Okamoto K, Toyokuni S, Uchida K et al. Formation of 8-hydroxy-2′-deoxyguanosine and 4-hydroxy-2-nonenal- modified proteins in human renal-cell carcinoma. Int J Cancer 1994; 58: 825-9.
    • (1994) Int J Cancer , vol.58 , pp. 825-829
    • Okamoto, K.1    Toyokuni, S.2    Uchida, K.3
  • 107
    • 0029932905 scopus 로고    scopus 로고
    • Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer
    • Okamoto K, Toyokuni S, Kim WJ et al. Overexpression of human mutT homologue gene messenger RNA in renal-cell carcinoma: evidence of persistent oxidative stress in cancer. Int J Cancer 1996; 65: 437-41.
    • (1996) Int J Cancer , vol.65 , pp. 437-441
    • Okamoto, K.1    Toyokuni, S.2    Kim, W.J.3
  • 108
    • 79960083593 scopus 로고    scopus 로고
    • Iron as a target of chemoprevention for longevity in humans
    • Toyokuni S Iron as a target of chemoprevention for longevity in humans. Free Radic Res 2011; 45: 906-17.
    • (2011) Free Radic Res , vol.45 , pp. 906-917
    • Toyokuni, S.1
  • 110
    • 84856327304 scopus 로고    scopus 로고
    • Asbestos (chrysotile, amosite, crocidolite, tremolite, actinolite, and anthophyllite)
    • A Review of Human Carcinogens; Part C: Arsenic, Metals, Fibres, and Dusts. Lyon, France: IARC
    • IARC. Asbestos (chrysotile, amosite, crocidolite, tremolite, actinolite, and anthophyllite). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. A Review of Human Carcinogens; Part C: Arsenic, Metals, Fibres, and Dusts. Vol. 100C. Lyon, France: IARC 2012; 219-309.
    • (2012) IARC Monographs on the Evaluation of Carcinogenic Risks to Humans , vol.100C , pp. 219-309
  • 111
    • 84964086140 scopus 로고    scopus 로고
    • Editorials this week: Asbestos scandal
    • Editorial
    • Editorial. Editorials this week: Asbestos scandal. Nature 2010; 468: 868.
    • (2010) Nature , vol.468 , pp. 868
  • 112
    • 84964086143 scopus 로고    scopus 로고
    • 79 Kubota workers killed by asbestos over 26 years (2005.06.30). The Daily Yomiuri..
    • 79 Kubota workers killed by asbestos over 26 years (2005.06.30). The Daily Yomiuri. 2005.
    • (2005)
  • 113
    • 84873118296 scopus 로고    scopus 로고
    • Metamorphosis of mesothelial cells wtih active horizontal motility in tissue culture
    • Nagai H, Chew S, Okazaki Y et al. Metamorphosis of mesothelial cells wtih active horizontal motility in tissue culture. Sci Rep 2013; 3: 1144.
    • (2013) Sci Rep , vol.3 , pp. 1144
    • Nagai, H.1    Chew, S.2    Okazaki, Y.3
  • 114
    • 84933036570 scopus 로고    scopus 로고
    • Receptor role of annexin A2 in the mesothelial endocytosis of crocidolite fibers
    • Yamashita K, Nagai H, Toyokuni S. Receptor role of annexin A2 in the mesothelial endocytosis of crocidolite fibers. Lab Invest 2015; 95: 749-64.
    • (2015) Lab Invest , vol.95 , pp. 749-764
    • Yamashita, K.1    Nagai, H.2    Toyokuni, S.3
  • 115
    • 26444458845 scopus 로고    scopus 로고
    • Advances in malignant mesothelioma
    • Robinson B, Lake R. Advances in malignant mesothelioma. N Engl J Med 2005; 353: 1591-603.
    • (2005) N Engl J Med , vol.353 , pp. 1591-1603
    • Robinson, B.1    Lake, R.2
  • 116
    • 84881670510 scopus 로고    scopus 로고
    • Potential years of life lost (PYLL) caused by asbestos-related diseases in the world
    • Diandini R, Takahashi K, Park EK et al. Potential years of life lost (PYLL) caused by asbestos-related diseases in the world. Am J Ind Med 2013; 56: 993-1000.
    • (2013) Am J Ind Med , vol.56 , pp. 993-1000
    • Diandini, R.1    Takahashi, K.2    Park, E.K.3
  • 117
    • 84867576196 scopus 로고    scopus 로고
    • Iron overload signature in chrysotile-induced malignant mesothelioma
    • Jiang L, Akatsuka S, Nagai H et al. Iron overload signature in chrysotile-induced malignant mesothelioma. J Pathol 2012; 228: 366-77.
    • (2012) J Pathol , vol.228 , pp. 366-377
    • Jiang, L.1    Akatsuka, S.2    Nagai, H.3
  • 118
    • 84891356983 scopus 로고    scopus 로고
    • Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production
    • Chew SH, Okazaki Y, Nagai H et al. Cancer-promoting role of adipocytes in asbestos-induced mesothelial carcinogenesis through dysregulated adipocytokine production. Carcinogenesis 2013; 35: 164-72.
    • (2013) Carcinogenesis , vol.35 , pp. 164-172
    • Chew, S.H.1    Okazaki, Y.2    Nagai, H.3
  • 119
    • 0027960580 scopus 로고
    • p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma
    • Cheng JQ, Jhanwar SC, Klein WM, et al. p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma. Cancer Res 1994; 54: 5547-51.
    • (1994) Cancer Res , vol.54 , pp. 5547-5551
    • Cheng, J.Q.1    Jhanwar, S.C.2    Klein, W.M.3
  • 121
    • 55449132870 scopus 로고    scopus 로고
    • Characteristics and modifying factors of asbestos-induced oxidative DNA damage
    • Jiang L, Nagai H, Ohara H et al. Characteristics and modifying factors of asbestos-induced oxidative DNA damage. Cancer Sci 2008; 99: 2142-51.
    • (2008) Cancer Sci , vol.99 , pp. 2142-2151
    • Jiang, L.1    Nagai, H.2    Ohara, H.3
  • 122
    • 81855194114 scopus 로고    scopus 로고
    • Asbestos surface provides a niche for oxidative modification
    • Nagai H, Ishihara T, Lee WH et al. Asbestos surface provides a niche for oxidative modification. Cancer Sci 2011; 102: 2118-25.
    • (2011) Cancer Sci , vol.102 , pp. 2118-2125
    • Nagai, H.1    Ishihara, T.2    Lee, W.H.3
  • 123
    • 84868602506 scopus 로고    scopus 로고
    • Distinct affinity of nuclear proteins to the surface of chrysotile and crocidolite
    • Kubo Y, Takenaka H, Nagai H, Toyokuni S. Distinct affinity of nuclear proteins to the surface of chrysotile and crocidolite. J Clin Biochem Nutr 2012; 51: 221-6.
    • (2012) J Clin Biochem Nutr , vol.51 , pp. 221-226
    • Kubo, Y.1    Takenaka, H.2    Nagai, H.3    Toyokuni, S.4
  • 124
    • 65549136242 scopus 로고    scopus 로고
    • Mechanisms of asbestos-induced carcinogenesis
    • Toyokuni S Mechanisms of asbestos-induced carcinogenesis. Nagoya J Med Sci 2009; 71: 1-10.
    • (2009) Nagoya J Med Sci , vol.71 , pp. 1-10
    • Toyokuni, S.1
  • 125
    • 84887970737 scopus 로고    scopus 로고
    • Deferasirox induces mesenchymal-epithelial transition in crocidolite-induced mesothelial carcinogenesis in rats
    • Nagai H, Okazaki Y, Chew SH, Misawa N, Yasui H, Toyokuni S. Deferasirox induces mesenchymal-epithelial transition in crocidolite-induced mesothelial carcinogenesis in rats. Cancer Prev Res 2013; 6: 1222-30.
    • (2013) Cancer Prev Res , vol.6 , pp. 1222-1230
    • Nagai, H.1    Okazaki, Y.2    Chew, S.H.3    Misawa, N.4    Yasui, H.5    Toyokuni, S.6
  • 126
    • 84904250717 scopus 로고    scopus 로고
    • Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma
    • Jiang L, Yamashita Y, Chew SH et al. Connective tissue growth factor and β-catenin constitute an autocrine loop for activation in rat sarcomatoid mesothelioma. J Pathol 2014; 233: 402-14.
    • (2014) J Pathol , vol.233 , pp. 402-414
    • Jiang, L.1    Yamashita, Y.2    Chew, S.H.3
  • 127
    • 84936751825 scopus 로고    scopus 로고
    • Malignant mesothelioma as an oxidative stress-induced cancer: An update
    • Chew SH, Toyokuni S. Malignant mesothelioma as an oxidative stress-induced cancer: An update. Free Radic Biol Med 2015; 86: 166-78.
    • (2015) Free Radic Biol Med , vol.86 , pp. 166-178
    • Chew, S.H.1    Toyokuni, S.2
  • 128
    • 0342819025 scopus 로고
    • Helical Microtubules of Graphitic Carbon
    • Iijima S Helical Microtubules of Graphitic Carbon. Nature 1991; 354: 56-8.
    • (1991) Nature , vol.354 , pp. 56-58
    • Iijima, S.1
  • 129
    • 59449088201 scopus 로고    scopus 로고
    • Potential applications of carbon nanotubes
    • Berlin Heidelberg: Springer
    • Endo M, Strano MS, Ajayan PM. Potential applications of carbon nanotubes. In: Carbon Nanotubes. Berlin Heidelberg: Springer, 2008; 13-62.
    • (2008) Carbon Nanotubes , pp. 13-62
    • Endo, M.1    Strano, M.S.2    Ajayan, P.M.3
  • 130
    • 80051947386 scopus 로고    scopus 로고
    • Fabrication and characterization of elastomeric polyester/carbon nanotubes nanocomposites for biomedical application
    • Meng ZX, Zheng W, Ding MH, et al. Fabrication and characterization of elastomeric polyester/carbon nanotubes nanocomposites for biomedical application. J Nanosci Nanotechnol 2011; 11: 3126-33.
    • (2011) J Nanosci Nanotechnol , vol.11 , pp. 3126-3133
    • Meng, Z.X.1    Zheng, W.2    Ding, M.H.3
  • 131
    • 46749153312 scopus 로고    scopus 로고
    • Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study
    • Poland C, Duffin R, Kinloch I et al. Carbon nanotubes introduced into the abdominal cavity of mice show asbestos-like pathogenicity in a pilot study. Nat Nanotechnol 2008; 3: 423-8.
    • (2008) Nat Nanotechnol , vol.3 , pp. 423-428
    • Poland, C.1    Duffin, R.2    Kinloch, I.3
  • 132
    • 83755178438 scopus 로고    scopus 로고
    • Diameter of multi-walled carbon nanotubes is a critical factor in mesothelial injury and subsequent carcinogenesis
    • Nagai H, Okazaki Y, Chew S, et al. Diameter of multi-walled carbon nanotubes is a critical factor in mesothelial injury and subsequent carcinogenesis. Proc Natl Acad Sci U S A 2011; 108: E1330-8.
    • (2011) Proc Natl Acad Sci U S A , vol.108 , pp. E1330-E1338
    • Nagai, H.1    Okazaki, Y.2    Chew, S.3
  • 133
    • 84923039683 scopus 로고    scopus 로고
    • Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes
    • Grosse Y, Loomis D, Guyton KZ et al. Carcinogenicity of fluoro-edenite, silicon carbide fibres and whiskers, and carbon nanotubes. Lancet Oncol 2014; 15: 1427-8.
    • (2014) Lancet Oncol , vol.15 , pp. 1427-1428
    • Grosse, Y.1    Loomis, D.2    Guyton, K.Z.3
  • 134
    • 40349113411 scopus 로고    scopus 로고
    • +/- mouse by intraperitoneal application of multi-wall carbon nanotube
    • +/- mouse by intraperitoneal application of multi-wall carbon nanotube. J Toxicol Sci 2008; 33: 105-16.
    • (2008) J Toxicol Sci , vol.33 , pp. 105-116
    • Takagi, A.1    Hirose, A.2    Nishimura, T.3
  • 135
    • 84864317151 scopus 로고    scopus 로고
    • Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice
    • Takagi A, Hirose A, Futakuchi M, Tsuda H, Kanno J. Dose-dependent mesothelioma induction by intraperitoneal administration of multi-wall carbon nanotubes in p53 heterozygous mice. Cancer Sci 2012; 103: 1440-4.
    • (2012) Cancer Sci , vol.103 , pp. 1440-1444
    • Takagi, A.1    Hirose, A.2    Futakuchi, M.3    Tsuda, H.4    Kanno, J.5
  • 136
    • 59949096454 scopus 로고    scopus 로고
    • Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats
    • Sakamoto Y, Nakae D, Fukumori N et al. Induction of mesothelioma by a single intrascrotal administration of multi-wall carbon nanotube in intact male Fischer 344 rats. J Toxicol Sci 2009; 34: 65-76.
    • (2009) J Toxicol Sci , vol.34 , pp. 65-76
    • Sakamoto, Y.1    Nakae, D.2    Fukumori, N.3
  • 137
    • 84885438020 scopus 로고    scopus 로고
    • Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats
    • Nagai H, Okazaki Y, Chew SH, et al. Intraperitoneal administration of tangled multiwalled carbon nanotubes of 15 nm in diameter does not induce mesothelial carcinogenesis in rats. Pathol Int 2013; 63: 457-62.
    • (2013) Pathol Int , vol.63 , pp. 457-462
    • Nagai, H.1    Okazaki, Y.2    Chew, S.H.3
  • 138
    • 84888871860 scopus 로고    scopus 로고
    • Genotoxicity and carcinogenicity risk of carbon nanotubes
    • Toyokuni S Genotoxicity and carcinogenicity risk of carbon nanotubes. Adv Drug Deliv Rev 2013; 65: 2098-110.
    • (2013) Adv Drug Deliv Rev , vol.65 , pp. 2098-2110
    • Toyokuni, S.1
  • 139
  • 140
    • 84959179231 scopus 로고    scopus 로고
    • Role of hemoglobin and transferrin in multi-wall carbon nanotube-induced mesothelial injury and carcinogenesis
    • press
    • Wang Y, Okazaki Y, Shi L, et al. Role of hemoglobin and transferrin in multi-wall carbon nanotube-induced mesothelial injury and carcinogenesis. Cancer Sci 2016 in press. doi: 10.1111/cas.12865.
    • (2016) Cancer Sci
    • Wang, Y.1    Okazaki, Y.2    Shi, L.3
  • 141
    • 84925018359 scopus 로고    scopus 로고
    • Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells
    • Funahashi S, Okazaki Y, Ito D et al. Asbestos and multi-walled carbon nanotubes generate distinct oxidative responses in inflammatory cells. J Clin Biochem Nutr 2015; 56: 111-7.
    • (2015) J Clin Biochem Nutr , vol.56 , pp. 111-117
    • Funahashi, S.1    Okazaki, Y.2    Ito, D.3
  • 143
    • 79251617843 scopus 로고    scopus 로고
    • Effects of non-thermal plasma on mammalian cells
    • e16270.
    • Kalghatgi S, Kelly CM, Cerchar E et al. Effects of non-thermal plasma on mammalian cells. PLoS One 2011; 6 e16270.
    • (2011) PLoS One , vol.6
    • Kalghatgi, S.1    Kelly, C.M.2    Cerchar, E.3
  • 144
    • 84945252809 scopus 로고    scopus 로고
    • Cancer therapy using non-thermal atmospheric pressure plasma with ultra-high electron density
    • Tanaka H, Mizuno M, Toyokuni S, et al. Cancer therapy using non-thermal atmospheric pressure plasma with ultra-high electron density. Phys Plasmas 2015; 22: 122004.
    • (2015) Phys Plasmas , vol.22 , pp. 122004
    • Tanaka, H.1    Mizuno, M.2    Toyokuni, S.3
  • 145
    • 84908622066 scopus 로고    scopus 로고
    • Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules
    • Okazaki Y, Wang Y, Tanaka H, et al. Direct exposure of non-equilibrium atmospheric pressure plasma confers simultaneous oxidative and ultraviolet modifications in biomolecules. J Clin Biochem Nutr 2014; 55: 207.
    • (2014) J Clin Biochem Nutr , vol.55 , pp. 207
    • Okazaki, Y.1    Wang, Y.2    Tanaka, H.3
  • 146
    • 77954018408 scopus 로고    scopus 로고
    • A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients
    • Isbary G, Morfill G, Schmidt HU et al. A first prospective randomized controlled trial to decrease bacterial load using cold atmospheric argon plasma on chronic wounds in patients. Br J Dermatol 2010; 163: 78-82.
    • (2010) Br J Dermatol , vol.163 , pp. 78-82
    • Isbary, G.1    Morfill, G.2    Schmidt, H.U.3
  • 147
    • 84860015631 scopus 로고    scopus 로고
    • Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma
    • Iseki S, Nakamura K, Hayashi M et al. Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma. Appl Phys Lett 2012; 100: 113702.
    • (2012) Appl Phys Lett , vol.100 , pp. 113702
    • Iseki, S.1    Nakamura, K.2    Hayashi, M.3
  • 148
    • 84893174750 scopus 로고    scopus 로고
    • Effect of Indirect Nonequilibrium Atmospheric Pressure Plasma on Anti-Proliferative Activity against Chronic Chemo-Resistant Ovarian Cancer Cells In Vitro and In Vivo
    • e81576.
    • Utsumi F, Kajiyama H, Nakamura K et al. Effect of Indirect Nonequilibrium Atmospheric Pressure Plasma on Anti-Proliferative Activity against Chronic Chemo-Resistant Ovarian Cancer Cells In Vitro and In Vivo. PLoS One 2013; 8 e81576.
    • (2013) PLoS One , vol.8
    • Utsumi, F.1    Kajiyama, H.2    Nakamura, K.3
  • 149
    • 84949317289 scopus 로고    scopus 로고
    • Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration
    • Ye F, Kaneko H, Nagasaka Y et al. Plasma-activated medium suppresses choroidal neovascularization in mice: a new therapeutic concept for age-related macular degeneration. Sci Rep 2015; 5: 7705.
    • (2015) Sci Rep , vol.5 , pp. 7705
    • Ye, F.1    Kaneko, H.2    Nagasaka, Y.3
  • 150
    • 84875153014 scopus 로고    scopus 로고
    • Plasma-activated medium selectively kills glioblastoma brain tumor cells by down-regulating a survival signaling molecule, AKT kinase
    • Tanaka H, Mizuno M, Ishikawa K et al. Plasma-activated medium selectively kills glioblastoma brain tumor cells by down-regulating a survival signaling molecule, AKT kinase. Plasma Med 2011; 1: 265-77.
    • (2011) Plasma Med , vol.1 , pp. 265-277
    • Tanaka, H.1    Mizuno, M.2    Ishikawa, K.3


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