Fenton Reaction Induced Cancer in Wild Type Rats Recapitulates Genomic Alterations Observed in Human Cancer

PLoS ONE

Volumn 7, Issue 8, 2012, Pages

  Akatsuka, Shinya ^a   Yamashita, Yoriko ^a   Ohara, Hiroki ^a   Liu, Yu Ting ^b   Izumiya, Masashi ^c   Abe, Koichiro ^c,d   Ochiai, Masako ^c   Jiang, Li ^a   Nagai, Hirotaka ^a,b   Okazaki, Yasumasa ^a   Murakami, Hideki ^e   Sekido, Yoshitaka ^e   Arai, Eri ^c   Kanai, Yae ^c   Hino, Okio ^f   Takahashi, Takashi ^a   Nakagama, Hitoshi ^c   Toyokuni, Shinya ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NATIONAL CANCER CENTER RESEARCH INSTITUTE   (Japan)

^d TEIKYO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^e AICHI CANCER CENTER HOSPITAL   (Japan)

^f JUNTENDO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; IRON; SCATTER FACTOR RECEPTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER SIZE; CHEMICAL CARCINOGENESIS; CHROMOSOME ANALYSIS; COMPARATIVE GENOMIC HYBRIDIZATION; CONTROLLED STUDY; COPY NUMBER VARIATION; DNA MICROARRAY; FENTON REACTION; GENE AMPLIFICATION; GENE CLUSTER; GENE DELETION; GENE LOCUS; GENETIC ASSOCIATION; HUMAN; HUMAN CELL; HUMAN GENOME; HUMAN TISSUE; HUMAN VERSUS ANIMAL COMPARISON; IN VIVO STUDY; IRON OVERLOAD; KIDNEY CARCINOMA; MALIGNANT MESOTHELIOMA; NONHUMAN; OXIDATIVE STRESS; RAT; WILD TYPE;

ANIMALS; CARCINOMA, RENAL CELL; CELL LINE, TUMOR; CHROMOSOME MAPPING; COMPARATIVE GENOMIC HYBRIDIZATION; GENE DELETION; GENE DOSAGE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENOME; HUMANS; IRON; KIDNEY NEOPLASMS; MODELS, CHEMICAL; NEOPLASMS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; RATS; RATS, INBRED F344;

RATTUS; RODENTIA;

EID: 84865603277     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0043403     Document Type: Article

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