Plasma-activated medium selectively kills glioblastoma brain tumor cells by down-regulating a survival signaling molecule, AKT kinase

Plasma Medicine

Volumn 1, Issue 3-4, 2011, Pages 265-277

  Tanaka, Hiromasa ^a,b   Mizuno, Masaaki ^b   Ishikawa, Kenji ^a   Nakamura, Kae ^b   Kajiyama, Hiroaki ^b   Kano, Hiroyuki ^c   Kikkawa, Fumitaka ^b   Hori, Masaru ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c NU EcoEngineering Co Ltd   (Japan)

Author keywords

AKT kinase; Glioblastoma; Plasma activated medium

Indexed keywords

BACTERIOPHAGES; BRAIN; CELL DEATH; CELL PROLIFERATION; CELLS; CYTOLOGY; ENZYMES; MOLECULES; SIGNAL TRANSDUCTION; TUMORS;

AKT KINASE; GLIOBLASTOMA CELLS; GLIOBLASTOMAS; INDUCED APOPTOSIS; MOLECULAR MECHANISM; MORPHOLOGICAL CHANGES; SIGNAL TRANSDUCTION PATHWAYS; SIGNALING MOLECULES;

CELL SIGNALING;

CASPASE 3; CASPASE 7; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CANCER SIZE; CELL PROLIFERATION; CELL SIZE; CONTROLLED STUDY; DOWN REGULATION; ENZYME REGULATION; GLIOBLASTOMA; HUMAN; HUMAN CELL; PLASMA; PLASMA ACTIVATED MEDIUM; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION;

EID: 84875153014     PISSN: 19475764     EISSN: 19475772     Source Type: Journal    
DOI: 10.1615/PlasmaMed.2012006275     Document Type: Article

References (21)

1. Fridman G, Friedman G, Gutsol A, Shekhter AB, Vasilets VN, Fridman A. Applied plasma medicine. Plasma Process Polym. 2008;5(6):503-33.
2. Kong MG, Kroesen G, Morfill G, Nosenko T, Shimizu T, van Dijk J, Zimmerman JL. Plasma medicine: an introductory review. New J Physics. 2009;11.
3. Laroussi M. Low temperature plasma-based sterilization: overview and state-of-the-art. Plasma Process Polym. 2005;2:391-400.
4. Morfill GE, Kong MG, Zimmermann JL. Focus on plasma medicine. New J Physics. 2009;11.
5. Heinlin J, Morfill G, Landthaler M, Stolz W, Isbary G, Zimmermann JL, Shimizo T, Karrer S. Plasma medicine: possible applications in dermatology. J Dtsch Dermatol Ges. 2010;8(12):968-76.
6. Stoffels E, Kieft IE, Sladek REJ. Superficial treatment of mammalian cells using plasma needle. J Phys D Appl Phys. 2003;36(23):2908-13.
7. Fridman G, Shereshevsky A, Jost MM, Brooks AD, Fridman A, Gutsol A, Vasilets V, Freidman, G. Floating electrode dielectric barrier discharge plasma in air promoting apoptotic behavior in melanoma skin cancer cell lines. Plasma Chem Plasma P. 2007;27(2):163-76.
8. Lee HJ, Shon CH, Kim YS, Kim S, Kim GC, Kong MG. Degradation of adhesion molecules of G361 melanoma cells by a non-thermal atmospheric pressure microplasma. New J Phys. 2009;11.
9. Gweon B, Kim M, Kim DB, Kim D, Kim H, Jung H, Shin JH, Choe W. Differential responses of human liver cancer and normal cells to atmospheric pressure plasma. Appl Phys Lett. 2011;99(6).
10. Kalghatgi S, Kelly CM, Cerchar E, Torabi B, Alekseev O, Fridman A, Freidman, G, Azizkhan-Clifford J. Effects of non-thermal plasma on mammalian cells. Plos One. 2011;6(1).
11. Iwasaki M, Inui H, Matsudaira Y, Kano H, Yoshida N, Ito M, Hori M. Nonequilibrium atmospheric pressure plasma with ultrahigh electron density and high performance for glass surface cleaning. Appl Phys Lett. 2008;92(8).
12. Jia FD, Sumi N, Ishikawa K, Kano H, Inui H, Kularatne J, Takeda K, Kondo H, Sekine M, Kono A, Hori M. Laser scattering diagnosis of a 60-hz non-equilibrium atmospheric pressure plasma jet. Appl Phys Express. 2011;4(2).
13. Iseki S, Ohta T, Aomatsu A, Ito M, Kano H, Higashijima Y, Hori, M. Rapid inactivation of Penicillium digitatum spores using high-density nonequilibrium atmospheric pressure plasma. Appl Phys Lett. 2010;96(15).
14. Iseki S, Nakamura K, Hayashi M, Tanaka H, Kondo H, Kajiyama H, Kano H, Kikkawa F, Hori M. Selective killing of ovarian cancer cells through induction of apoptosis by nonequilibrium atmospheric pressure plasma. Appl Phys Lett. 2012;100(11).
15. Sato T, Yokoyama M, Johkura K. A key inactivation factor of HeLa cell viability by a plasma flow. J Phys D Appl Phys. 2011;44(37).
16. Lee JJ, Kim BC, Park MJ, Lee YS, Kim YN, Lee BL, Lee JS. PTEN status switches cell fate between premature senescence and apoptosis in glioma exposed to ionizing radiation. Cell Death Differ. 2011;18(4):666-77.
17. Weizman L, Ben Sira L, Joskowicz L, Constantini S, Precel R, Shofty B, Ben Bashat, D. Automatic segmentation, internal classification, and follow-up of optic pathway gliomas in MRI. Med Image Anal. 2012;16(1):177-88.
18. Vandamme M, Robert E, Lerondel S, Sarron V, Ries D, Dozias S, Dozias S, Sobilo J, Gosset D, Kieda C, Legrain B, Pouvesle JM, Pape AL. ROS implication in a new antitumor strategy based on non-thermal plasma. Int J Cancer. 2012;130(9):2185-94.
19. Ventura JJ, Nebreda AR. Protein kinases and phosphatases as therapeutic targets in cancer. Clinical and Translational Oncology: Official Publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico. 2006;8(3):153-60. Epub 2006/05/02.
20. Haanen C, Vermes I. Apoptosis and inflammation. Mediators of inflammation. 1995;4(1):5-15. Epub 1995/01/01.
21. Kandel ES, Skeen J, Majewski N, Di Cristofano A, Pandolfi PP, Feliciano CS, Gartil A, Hay N. Activation of Akt/protein kinase B overcomes a G(2)/m cell cycle checkpoint induced by DNA damage. Molec Cell Biol. 2002;22(22):7831-41. Epub 2002/10/23.