-
1
-
-
84889051321
-
RNA polymerase II C-terminal domain: Tethering transcription to transcript and template
-
J.L. Corden RNA polymerase II C-terminal domain: tethering transcription to transcript and template Chem. Rev. 113 2013 8423 8455
-
(2013)
Chem. Rev.
, vol.113
, pp. 8423-8455
-
-
Corden, J.L.1
-
2
-
-
84888991588
-
The RNA polymerase II carboxy-terminal domain (CTD) code
-
D. Eick, and M. Geyer The RNA polymerase II carboxy-terminal domain (CTD) code Chem. Rev. 113 2013 8456 8490
-
(2013)
Chem. Rev.
, vol.113
, pp. 8456-8490
-
-
Eick, D.1
Geyer, M.2
-
3
-
-
84889028380
-
The writers, readers, and functions of the RNA polymerase II C-terminal domain code
-
C. Jeronimo, A.R. Bataille, and F. Robert The writers, readers, and functions of the RNA polymerase II C-terminal domain code Chem. Rev. 113 2013 8491 8522
-
(2013)
Chem. Rev.
, vol.113
, pp. 8491-8522
-
-
Jeronimo, C.1
Bataille, A.R.2
Robert, F.3
-
4
-
-
84871402053
-
The CTD code of RNA polymerase II: A structural view
-
O. Jasnovidova, and R. Stefl The CTD code of RNA polymerase II: a structural view Wiley Interdiscip. Rev. RNA 4 2013 1 16
-
(2013)
Wiley Interdiscip. Rev. RNA
, vol.4
, pp. 1-16
-
-
Jasnovidova, O.1
Stefl, R.2
-
5
-
-
84863610013
-
Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo
-
S.M. Ranuncolo, S. Ghosh, J.A. Hanover, G.W. Hart, and B.A. Lewis Evidence of the involvement of O-GlcNAc-modified human RNA polymerase II CTD in transcription in vitro and in vivo J. Biol. Chem. 287 2012 23549 23561
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 23549-23561
-
-
Ranuncolo, S.M.1
Ghosh, S.2
Hanover, J.A.3
Hart, G.W.4
Lewis, B.A.5
-
6
-
-
79953288782
-
The C-terminal domain of RNA polymerase II is modified by site-specific methylation
-
R.J. Sims III, L.A. Rojas, D. Beck, R. Bonasio, R. Schuller, W.J. Drury 3rd, D. Eick, and D. Reinberg The C-terminal domain of RNA polymerase II is modified by site-specific methylation Science 332 2011 99 103
-
(2011)
Science
, vol.332
, pp. 99-103
-
-
Sims, R.J.1
Rojas, L.A.2
Beck, D.3
Bonasio, R.4
Schuller, R.5
Drury, W.J.6
Eick, D.7
Reinberg, D.8
-
7
-
-
84887207641
-
Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells
-
S. Schroder, E. Herker, F. Itzen, D. He, S. Thomas, D.A. Gilchrist, K. Kaehlcke, S. Cho, K.S. Pollard, J.A. Capra, M. Schnolzer, P.A. Cole, M. Geyer, B.G. Bruneau, K. Adelman, and M. Ott Acetylation of RNA polymerase II regulates growth-factor-induced gene transcription in mammalian cells Mol. Cell 52 2013 314 324
-
(2013)
Mol. Cell
, vol.52
, pp. 314-324
-
-
Schroder, S.1
Herker, E.2
Itzen, F.3
He, D.4
Thomas, S.5
Gilchrist, D.A.6
Kaehlcke, K.7
Cho, S.8
Pollard, K.S.9
Capra, J.A.10
Schnolzer, M.11
Cole, P.A.12
Geyer, M.13
Bruneau, B.G.14
Adelman, K.15
Ott, M.16
-
8
-
-
84950310440
-
Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II
-
K. Voss, I. Forne, N. Descostes, C. Hintermair, R. Schuller, M.A. Maqbool, M. Heidemann, A. Flatley, A. Imhof, M. Gut, I. Gut, E. Kremmer, J.C. Andrau, and D. Eick Site-specific methylation and acetylation of lysine residues in the C-terminal domain (CTD) of RNA polymerase II Transcription 6 2015 91 101
-
(2015)
Transcription
, vol.6
, pp. 91-101
-
-
Voss, K.1
Forne, I.2
Descostes, N.3
Hintermair, C.4
Schuller, R.5
Maqbool, M.A.6
Heidemann, M.7
Flatley, A.8
Imhof, A.9
Gut, M.10
Gut, I.11
Kremmer, E.12
Andrau, J.C.13
Eick, D.14
-
9
-
-
34547167489
-
Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells
-
H. Li, Z. Zhang, B. Wang, J. Zhang, Y. Zhao, and Y. Jin Wwp2-mediated ubiquitination of the RNA polymerase II large subunit in mouse embryonic pluripotent stem cells Mol. Cell. Biol. 27 2007 5296 5305
-
(2007)
Mol. Cell. Biol.
, vol.27
, pp. 5296-5305
-
-
Li, H.1
Zhang, Z.2
Wang, B.3
Zhang, J.4
Zhao, Y.5
Jin, Y.6
-
10
-
-
84953897634
-
SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination
-
D.Y. Zhao, G. Gish, U. Braunschweig, Y. Li, Z. Ni, F.W. Schmitges, G. Zhong, K. Liu, W. Li, J. Moffat, M. Vedadi, J. Min, T.J. Pawson, B.J. Blencowe, and J.F. Greenblatt SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination Nature 529 2016 48 53
-
(2016)
Nature
, vol.529
, pp. 48-53
-
-
Zhao, D.Y.1
Gish, G.2
Braunschweig, U.3
Li, Y.4
Ni, Z.5
Schmitges, F.W.6
Zhong, G.7
Liu, K.8
Li, W.9
Moffat, J.10
Vedadi, M.11
Min, J.12
Pawson, T.J.13
Blencowe, B.J.14
Greenblatt, J.F.15
-
11
-
-
84964357500
-
Methylation of RNA polymerase II non-consensus lysine residues marks early transcription in mammalian cells
-
J.D. Dias, T. Rito, E. Torlai Triglia, A. Kukalev, C. Ferrai, M. Chotalia, E. Brookes, H. Kimura, and A. Pombo Methylation of RNA polymerase II non-consensus lysine residues marks early transcription in mammalian cells Elife 4 2015 e11215
-
(2015)
Elife
, vol.4
-
-
Dias, J.D.1
Rito, T.2
Torlai Triglia, E.3
Kukalev, A.4
Ferrai, C.5
Chotalia, M.6
Brookes, E.7
Kimura, H.8
Pombo, A.9
-
12
-
-
77957766550
-
Uniform transitions of the general RNA polymerase II transcription complex
-
A. Mayer, M. Lidschreiber, M. Siebert, K. Leike, J. Soding, and P. Cramer Uniform transitions of the general RNA polymerase II transcription complex Nat. Struct. Mol. Biol. 17 2010 1272 1278
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1272-1278
-
-
Mayer, A.1
Lidschreiber, M.2
Siebert, M.3
Leike, K.4
Soding, J.5
Cramer, P.6
-
13
-
-
84856273602
-
A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes
-
A.R. Bataille, C. Jeronimo, P.E. Jacques, L. Laramee, M.E. Fortin, A. Forest, M. Bergeron, S.D. Hanes, and F. Robert A universal RNA polymerase II CTD cycle is orchestrated by complex interplays between kinase, phosphatase, and isomerase enzymes along genes Mol. Cell 45 2012 158 170
-
(2012)
Mol. Cell
, vol.45
, pp. 158-170
-
-
Bataille, A.R.1
Jeronimo, C.2
Jacques, P.E.3
Laramee, L.4
Fortin, M.E.5
Forest, A.6
Bergeron, M.7
Hanes, S.D.8
Robert, F.9
-
14
-
-
84939599359
-
Modifications of RNA polymerase II CTD: Connections to the histone code and cellular function
-
R. Srivastava, and S.H. Ahn Modifications of RNA polymerase II CTD: connections to the histone code and cellular function Biotechnol. Adv. 33 2015 856 872
-
(2015)
Biotechnol. Adv.
, vol.33
, pp. 856-872
-
-
Srivastava, R.1
Ahn, S.H.2
-
15
-
-
84922226115
-
Chromatin modification by the RNA Polymerase II elongation complex
-
J.C. Tanny Chromatin modification by the RNA Polymerase II elongation complex Transcription 5 2014 e988093
-
(2014)
Transcription
, vol.5
-
-
Tanny, J.C.1
-
16
-
-
37249015899
-
Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7
-
R.D. Chapman, M. Heidemann, T.K. Albert, R. Mailhammer, A. Flatley, M. Meisterernst, E. Kremmer, and D. Eick Transcribing RNA polymerase II is phosphorylated at CTD residue serine-7 Science 318 2007 1780 1782
-
(2007)
Science
, vol.318
, pp. 1780-1782
-
-
Chapman, R.D.1
Heidemann, M.2
Albert, T.K.3
Mailhammer, R.4
Flatley, A.5
Meisterernst, M.6
Kremmer, E.7
Eick, D.8
-
17
-
-
64749116042
-
Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation
-
A.L. Mosley, S.G. Pattenden, M. Carey, S. Venkatesh, J.M. Gilmore, L. Florens, J.L. Workman, and M.P. Washburn Rtr1 is a CTD phosphatase that regulates RNA polymerase II during the transition from serine 5 to serine 2 phosphorylation Mol. Cell 34 2009 168 178
-
(2009)
Mol. Cell
, vol.34
, pp. 168-178
-
-
Mosley, A.L.1
Pattenden, S.G.2
Carey, M.3
Venkatesh, S.4
Gilmore, J.M.5
Florens, L.6
Workman, J.L.7
Washburn, M.P.8
-
18
-
-
84917706091
-
The Ssu72 phosphatase mediates the RNA polymerase II initiation-elongation transition
-
J.D. Rosado-Lugo, and M. Hampsey The Ssu72 phosphatase mediates the RNA polymerase II initiation-elongation transition J. Biol. Chem. 289 2014 33916 33926
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 33916-33926
-
-
Rosado-Lugo, J.D.1
Hampsey, M.2
-
19
-
-
0035893314
-
Opposing effects of Ctk1 kinase and Fcp1 phosphatase at ser 2 of the RNA polymerase II C-terminal domain
-
E.J. Cho, M.S. Kobor, M. Kim, J. Greenblatt, and S. Buratowski Opposing effects of Ctk1 kinase and Fcp1 phosphatase at Ser 2 of the RNA polymerase II C-terminal domain Genes Dev. 15 2001 3319 3329
-
(2001)
Genes Dev.
, vol.15
, pp. 3319-3329
-
-
Cho, E.J.1
Kobor, M.S.2
Kim, M.3
Greenblatt, J.4
Buratowski, S.5
-
20
-
-
0029037999
-
Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations
-
M. West, and J.L. Corden Construction and analysis of yeast RNA polymerase II CTD deletion and substitution mutations Genetics 140 1995 1223 1233
-
(1995)
Genetics
, vol.140
, pp. 1223-1233
-
-
West, M.1
Corden, J.L.2
-
21
-
-
2942616943
-
Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae
-
C.B. Wilcox, A. Rossettini, and S.D. Hanes Genetic interactions with C-terminal domain (CTD) kinases and the CTD of RNA Pol II suggest a role for ESS1 in transcription initiation and elongation in Saccharomyces cerevisiae Genetics 167 2004 93 105
-
(2004)
Genetics
, vol.167
, pp. 93-105
-
-
Wilcox, C.B.1
Rossettini, A.2
Hanes, S.D.3
-
22
-
-
84957581254
-
Direct analysis of phosphorylation sites on the Rpb1 C-terminal domain of RNA polymerase II
-
H. Suh, S.B. Ficarro, U.B. Kang, Y. Chun, J.A. Marto, and S. Buratowski Direct analysis of phosphorylation sites on the Rpb1 C-terminal domain of RNA polymerase II Mol. Cell 61 2016 297 304
-
(2016)
Mol. Cell
, vol.61
, pp. 297-304
-
-
Suh, H.1
Ficarro, S.B.2
Kang, U.B.3
Chun, Y.4
Marto, J.A.5
Buratowski, S.6
-
23
-
-
84957594407
-
Heptad-specific phosphorylation of RNA Polymerase II CTD
-
R. Schuller, I. Forne, T. Straub, A. Schreieck, Y. Texier, N. Shah, T.M. Decker, P. Cramer, A. Imhof, and D. Eick Heptad-specific phosphorylation of RNA Polymerase II CTD Mol. Cell 61 2016 305 314
-
(2016)
Mol. Cell
, vol.61
, pp. 305-314
-
-
Schuller, R.1
Forne, I.2
Straub, T.3
Schreieck, A.4
Texier, Y.5
Shah, N.6
Decker, T.M.7
Cramer, P.8
Imhof, A.9
Eick, D.10
-
24
-
-
84923811117
-
The mediator complex: A central integrator of transcription
-
B.L. Allen, and D.J. Taatjes The mediator complex: a central integrator of transcription Nat. Rev. Mol. Cell Biol. 16 2015 155 166
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 155-166
-
-
Allen, B.L.1
Taatjes, D.J.2
-
25
-
-
84880273878
-
Mechanisms of mediator complex action in transcriptional activation
-
S.A. Ansari, and R.H. Morse Mechanisms of mediator complex action in transcriptional activation Cell. Mol. Life Sci. 70 2013 2743 2756
-
(2013)
Cell. Mol. Life Sci.
, vol.70
, pp. 2743-2756
-
-
Ansari, S.A.1
Morse, R.H.2
-
27
-
-
84923804845
-
Structural basis of transcription initiation by RNA polymerase II
-
S. Sainsbury, C. Bernecky, and P. Cramer Structural basis of transcription initiation by RNA polymerase II Nat. Rev. Mol. Cell Biol. 16 2015 129 143
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 129-143
-
-
Sainsbury, S.1
Bernecky, C.2
Cramer, P.3
-
28
-
-
84888130540
-
Structural insights into transcription initiation by RNA polymerase II
-
S. Grunberg, and S. Hahn Structural insights into transcription initiation by RNA polymerase II Trends Biochem. Sci. 38 2013 603 611
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 603-611
-
-
Grunberg, S.1
Hahn, S.2
-
29
-
-
0029095126
-
Requirement for TFIIH kinase activity in transcription by RNA polymerase II
-
S. Akoulitchev, T.P. Makela, R.A. Weinberg, and D. Reinberg Requirement for TFIIH kinase activity in transcription by RNA polymerase II Nature 377 1995 557 560
-
(1995)
Nature
, vol.377
, pp. 557-560
-
-
Akoulitchev, S.1
Makela, T.P.2
Weinberg, R.A.3
Reinberg, D.4
-
30
-
-
0842347413
-
Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex
-
Y. Liu, C. Kung, J. Fishburn, A.Z. Ansari, K.M. Shokat, and S. Hahn Two cyclin-dependent kinases promote RNA polymerase II transcription and formation of the scaffold complex Mol. Cell. Biol. 24 2004 1721 1735
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 1721-1735
-
-
Liu, Y.1
Kung, C.2
Fishburn, J.3
Ansari, A.Z.4
Shokat, K.M.5
Hahn, S.6
-
31
-
-
0030947346
-
Evidence for a mediator cycle at the initiation of transcription
-
J.Q. Svejstrup, Y. Li, J. Fellows, A. Gnatt, S. Bjorklund, and R.D. Kornberg Evidence for a mediator cycle at the initiation of transcription Proc. Natl. Acad. Sci. U. S. A. 94 1997 6075 6078
-
(1997)
Proc. Natl. Acad. Sci. U. S. A.
, vol.94
, pp. 6075-6078
-
-
Svejstrup, J.Q.1
Li, Y.2
Fellows, J.3
Gnatt, A.4
Bjorklund, S.5
Kornberg, R.D.6
-
32
-
-
34347273423
-
Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator
-
T.M. Sogaard, and J.Q. Svejstrup Hyperphosphorylation of the C-terminal repeat domain of RNA polymerase II facilitates dissociation of its complex with mediator J. Biol. Chem. 282 2007 14113 14120
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 14113-14120
-
-
Sogaard, T.M.1
Svejstrup, J.Q.2
-
33
-
-
77957786100
-
Gene-specific RNA polymerase II phosphorylation and the CTD code
-
H. Kim, B. Erickson, W. Luo, D. Seward, J.H. Graber, D.D. Pollock, P.C. Megee, and D.L. Bentley Gene-specific RNA polymerase II phosphorylation and the CTD code Nat. Struct. Mol. Biol. 17 2010 1279 1286
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1279-1286
-
-
Kim, H.1
Erickson, B.2
Luo, W.3
Seward, D.4
Graber, J.H.5
Pollock, D.D.6
Megee, P.C.7
Bentley, D.L.8
-
34
-
-
77956344274
-
Chemical-genomic dissection of the CTD code
-
J.R. Tietjen, D.W. Zhang, J.B. Rodriguez-Molina, B.E. White, M.S. Akhtar, M. Heidemann, X. Li, R.D. Chapman, K. Shokat, S. Keles, D. Eick, and A.Z. Ansari Chemical-genomic dissection of the CTD code Nat. Struct. Mol. Biol. 17 2010 1154 1161
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 1154-1161
-
-
Tietjen, J.R.1
Zhang, D.W.2
Rodriguez-Molina, J.B.3
White, B.E.4
Akhtar, M.S.5
Heidemann, M.6
Li, X.7
Chapman, R.D.8
Shokat, K.9
Keles, S.10
Eick, D.11
Ansari, A.Z.12
-
35
-
-
79960284319
-
Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover
-
K. Helenius, Y. Yang, T.V. Tselykh, H.K. Pessa, M.J. Frilander, and T.P. Makela Requirement of TFIIH kinase subunit Mat1 for RNA Pol II C-terminal domain Ser5 phosphorylation, transcription and mRNA turnover Nucleic Acids Res. 39 2011 5025 5035
-
(2011)
Nucleic Acids Res.
, vol.39
, pp. 5025-5035
-
-
Helenius, K.1
Yang, Y.2
Tselykh, T.V.3
Pessa, H.K.4
Frilander, M.J.5
Makela, T.P.6
-
36
-
-
84901235459
-
TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape
-
K.H. Wong, Y. Jin, and K. Struhl TFIIH phosphorylation of the Pol II CTD stimulates mediator dissociation from the preinitiation complex and promoter escape Mol. Cell 54 2014 601 612
-
(2014)
Mol. Cell
, vol.54
, pp. 601-612
-
-
Wong, K.H.1
Jin, Y.2
Struhl, K.3
-
37
-
-
84902073419
-
Kin28 regulates the transient association of mediator with core promoters
-
C. Jeronimo, and F. Robert Kin28 regulates the transient association of mediator with core promoters Nat. Struct. Mol. Biol. 21 2014 449 455
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 449-455
-
-
Jeronimo, C.1
Robert, F.2
-
38
-
-
52049084405
-
The anchor-away technique: Rapid, conditional establishment of yeast mutant phenotypes
-
H. Haruki, J. Nishikawa, and U.K. Laemmli The anchor-away technique: rapid, conditional establishment of yeast mutant phenotypes Mol. Cell 31 2008 925 932
-
(2008)
Mol. Cell
, vol.31
, pp. 925-932
-
-
Haruki, H.1
Nishikawa, J.2
Laemmli, U.K.3
-
39
-
-
0026731557
-
Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II
-
H. Lu, L. Zawel, L. Fisher, J.M. Egly, and D. Reinberg Human general transcription factor IIH phosphorylates the C-terminal domain of RNA polymerase II Nature 358 1992 641 645
-
(1992)
Nature
, vol.358
, pp. 641-645
-
-
Lu, H.1
Zawel, L.2
Fisher, L.3
Egly, J.M.4
Reinberg, D.5
-
40
-
-
0034307008
-
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription
-
P. Komarnitsky, E.J. Cho, and S. Buratowski Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcription Genes Dev. 14 2000 2452 2460
-
(2000)
Genes Dev.
, vol.14
, pp. 2452-2460
-
-
Komarnitsky, P.1
Cho, E.J.2
Buratowski, S.3
-
41
-
-
65549156025
-
TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II
-
M.S. Akhtar, M. Heidemann, J.R. Tietjen, D.W. Zhang, R.D. Chapman, D. Eick, and A.Z. Ansari TFIIH kinase places bivalent marks on the carboxy-terminal domain of RNA polymerase II Mol. Cell 34 2009 387 393
-
(2009)
Mol. Cell
, vol.34
, pp. 387-393
-
-
Akhtar, M.S.1
Heidemann, M.2
Tietjen, J.R.3
Zhang, D.W.4
Chapman, R.D.5
Eick, D.6
Ansari, A.Z.7
-
42
-
-
70350442978
-
TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II
-
K. Glover-Cutter, S. Larochelle, B. Erickson, C. Zhang, K. Shokat, R.P. Fisher, and D.L. Bentley TFIIH-associated Cdk7 kinase functions in phosphorylation of C-terminal domain Ser7 residues, promoter-proximal pausing, and termination by RNA polymerase II Mol. Cell. Biol. 29 2009 5455 5464
-
(2009)
Mol. Cell. Biol.
, vol.29
, pp. 5455-5464
-
-
Glover-Cutter, K.1
Larochelle, S.2
Erickson, B.3
Zhang, C.4
Shokat, K.5
Fisher, R.P.6
Bentley, D.L.7
-
43
-
-
70350389837
-
Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7
-
M. Kim, H. Suh, E.J. Cho, and S. Buratowski Phosphorylation of the yeast Rpb1 C-terminal domain at serines 2, 5, and 7 J. Biol. Chem. 284 2009 26421 26426
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 26421-26426
-
-
Kim, M.1
Suh, H.2
Cho, E.J.3
Buratowski, S.4
-
44
-
-
0141557776
-
Cdk7 is required for full activation of drosophila heat shock genes and RNA polymerase II phosphorylation in vivo
-
B.E. Schwartz, S. Larochelle, B. Suter, and J.T. Lis Cdk7 is required for full activation of drosophila heat shock genes and RNA polymerase II phosphorylation in vivo Mol. Cell. Biol. 23 2003 6876 6886
-
(2003)
Mol. Cell. Biol.
, vol.23
, pp. 6876-6886
-
-
Schwartz, B.E.1
Larochelle, S.2
Suter, B.3
Lis, J.T.4
-
45
-
-
84869095110
-
Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II
-
S. Larochelle, R. Amat, K. Glover-Cutter, M. Sanso, C. Zhang, J.J. Allen, K.M. Shokat, D.L. Bentley, and R.P. Fisher Cyclin-dependent kinase control of the initiation-to-elongation switch of RNA polymerase II Nat. Struct. Mol. Biol. 19 2012 1108 1115
-
(2012)
Nat. Struct. Mol. Biol.
, vol.19
, pp. 1108-1115
-
-
Larochelle, S.1
Amat, R.2
Glover-Cutter, K.3
Sanso, M.4
Zhang, C.5
Allen, J.J.6
Shokat, K.M.7
Bentley, D.L.8
Fisher, R.P.9
-
46
-
-
84906956187
-
Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells
-
T.W. Kelso, K. Baumgart, J. Eickhoff, T. Albert, C. Antrecht, S. Lemcke, B. Klebl, and M. Meisterernst Cyclin-dependent kinase 7 controls mRNA synthesis by affecting stability of preinitiation complexes, leading to altered gene expression, cell cycle progression, and survival of tumor cells Mol. Cell. Biol. 34 2014 3675 3688
-
(2014)
Mol. Cell. Biol.
, vol.34
, pp. 3675-3688
-
-
Kelso, T.W.1
Baumgart, K.2
Eickhoff, J.3
Albert, T.4
Antrecht, C.5
Lemcke, S.6
Klebl, B.7
Meisterernst, M.8
-
47
-
-
84904963991
-
Targeting transcription regulation in cancer with a covalent CDK7 inhibitor
-
N. Kwiatkowski, T. Zhang, P.B. Rahl, B.J. Abraham, J. Reddy, S.B. Ficarro, A. Dastur, A. Amzallag, S. Ramaswamy, B. Tesar, C.E. Jenkins, N.M. Hannett, D. McMillin, T. Sanda, T. Sim, N.D. Kim, T. Look, C.S. Mitsiades, A.P. Weng, J.R. Brown, C.H. Benes, J.A. Marto, R.A. Young, and N.S. Gray Targeting transcription regulation in cancer with a covalent CDK7 inhibitor Nature 511 2014 616 620
-
(2014)
Nature
, vol.511
, pp. 616-620
-
-
Kwiatkowski, N.1
Zhang, T.2
Rahl, P.B.3
Abraham, B.J.4
Reddy, J.5
Ficarro, S.B.6
Dastur, A.7
Amzallag, A.8
Ramaswamy, S.9
Tesar, B.10
Jenkins, C.E.11
Hannett, N.M.12
McMillin, D.13
Sanda, T.14
Sim, T.15
Kim, N.D.16
Look, T.17
Mitsiades, C.S.18
Weng, A.P.19
Brown, J.R.20
Benes, C.H.21
Marto, J.A.22
Young, R.A.23
Gray, N.S.24
more..
-
48
-
-
84911942289
-
CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer
-
E. Chipumuro, E. Marco, C.L. Christensen, N. Kwiatkowski, T. Zhang, C.M. Hatheway, B.J. Abraham, B. Sharma, C. Yeung, A. Altabef, A. Perez-Atayde, K.K. Wong, G.C. Yuan, N.S. Gray, R.A. Young, and R.E. George CDK7 inhibition suppresses super-enhancer-linked oncogenic transcription in MYCN-driven cancer Cell 159 2014 1126 1139
-
(2014)
Cell
, vol.159
, pp. 1126-1139
-
-
Chipumuro, E.1
Marco, E.2
Christensen, C.L.3
Kwiatkowski, N.4
Zhang, T.5
Hatheway, C.M.6
Abraham, B.J.7
Sharma, B.8
Yeung, C.9
Altabef, A.10
Perez-Atayde, A.11
Wong, K.K.12
Yuan, G.C.13
Gray, N.S.14
Young, R.A.15
George, R.E.16
-
49
-
-
84939530621
-
THZ1 reveals roles for Cdk7 in Co-transcriptional capping and pausing
-
K.A. Nilson, J. Guo, M.E. Turek, J.E. Brogie, E. Delaney, D.S. Luse, and D.H. Price THZ1 reveals roles for Cdk7 in Co-transcriptional capping and pausing Mol. Cell 59 2015 576 587
-
(2015)
Mol. Cell
, vol.59
, pp. 576-587
-
-
Nilson, K.A.1
Guo, J.2
Turek, M.E.3
Brogie, J.E.4
Delaney, E.5
Luse, D.S.6
Price, D.H.7
-
50
-
-
0033515521
-
NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation
-
Y. Yamaguchi, T. Takagi, T. Wada, K. Yano, A. Furuya, S. Sugimoto, J. Hasegawa, and H. Handa NELF, a multisubunit complex containing RD, cooperates with DSIF to repress RNA polymerase II elongation Cell 97 1999 41 51
-
(1999)
Cell
, vol.97
, pp. 41-51
-
-
Yamaguchi, Y.1
Takagi, T.2
Wada, T.3
Yano, K.4
Furuya, A.5
Sugimoto, S.6
Hasegawa, J.7
Handa, H.8
-
51
-
-
14444275279
-
DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs
-
T. Wada, T. Takagi, Y. Yamaguchi, A. Ferdous, T. Imai, S. Hirose, S. Sugimoto, K. Yano, G.A. Hartzog, F. Winston, S. Buratowski, and H. Handa DSIF, a novel transcription elongation factor that regulates RNA polymerase II processivity, is composed of human Spt4 and Spt5 homologs Genes Dev. 12 1998 343 356
-
(1998)
Genes Dev.
, vol.12
, pp. 343-356
-
-
Wada, T.1
Takagi, T.2
Yamaguchi, Y.3
Ferdous, A.4
Imai, T.5
Hirose, S.6
Sugimoto, S.7
Yano, K.8
Hartzog, G.A.9
Winston, F.10
Buratowski, S.11
Handa, H.12
-
52
-
-
84872393129
-
Transcription elongation factors DSIF and NELF: Promoter-proximal pausing and beyond
-
Y. Yamaguchi, H. Shibata, and H. Handa Transcription elongation factors DSIF and NELF: promoter-proximal pausing and beyond Biochim. Biophys. Acta 1829 2013 98 104
-
(2013)
Biochim. Biophys. Acta
, vol.1829
, pp. 98-104
-
-
Yamaguchi, Y.1
Shibata, H.2
Handa, H.3
-
53
-
-
84923780299
-
Getting up to speed with transcription elongation by RNA polymerase II
-
I. Jonkers, and J.T. Lis Getting up to speed with transcription elongation by RNA polymerase II Nat. Rev. Mol. Cell Biol. 16 2015 167 177
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 167-177
-
-
Jonkers, I.1
Lis, J.T.2
-
54
-
-
78650566210
-
Pol II waiting in the starting gates: Regulating the transition from transcription initiation into productive elongation
-
S. Nechaev, and K. Adelman Pol II waiting in the starting gates: regulating the transition from transcription initiation into productive elongation Biochim. Biophys. Acta 1809 2011 34 45
-
(2011)
Biochim. Biophys. Acta
, vol.1809
, pp. 34-45
-
-
Nechaev, S.1
Adelman, K.2
-
55
-
-
33746403681
-
Controlling the elongation phase of transcription with P-TEFb
-
B.M. Peterlin, and D.H. Price Controlling the elongation phase of transcription with P-TEFb Mol. Cell 23 2006 297 305
-
(2006)
Mol. Cell
, vol.23
, pp. 297-305
-
-
Peterlin, B.M.1
Price, D.H.2
-
56
-
-
5444225805
-
Elongation by RNA polymerase II: The short and long of it
-
R.J. Sims III, R. Belotserkovskaya, and D. Reinberg Elongation by RNA polymerase II: the short and long of it Genes Dev. 18 2004 2437 2468
-
(2004)
Genes Dev.
, vol.18
, pp. 2437-2468
-
-
Sims, R.J.1
Belotserkovskaya, R.2
Reinberg, D.3
-
57
-
-
84939559067
-
Revisiting the function of CDK7 in transcription by virtue of a recently described TFIIH kinase inhibitor
-
F. Coin, and J.M. Egly Revisiting the function of CDK7 in transcription by virtue of a recently described TFIIH kinase inhibitor Mol. Cell 59 2015 513 514
-
(2015)
Mol. Cell
, vol.59
, pp. 513-514
-
-
Coin, F.1
Egly, J.M.2
-
58
-
-
79960440046
-
The initiation factor TFE and the elongation factor Spt4/5 compete for the RNAP clamp during transcription initiation and elongation
-
D. Grohmann, J. Nagy, A. Chakraborty, D. Klose, D. Fielden, R.H. Ebright, J. Michaelis, and F. Werner The initiation factor TFE and the elongation factor Spt4/5 compete for the RNAP clamp during transcription initiation and elongation Mol. Cell 43 2011 263 274
-
(2011)
Mol. Cell
, vol.43
, pp. 263-274
-
-
Grohmann, D.1
Nagy, J.2
Chakraborty, A.3
Klose, D.4
Fielden, D.5
Ebright, R.H.6
Michaelis, J.7
Werner, F.8
-
59
-
-
79953779997
-
Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity
-
F.W. Martinez-Rucobo, S. Sainsbury, A.C. Cheung, and P. Cramer Architecture of the RNA polymerase-Spt4/5 complex and basis of universal transcription processivity EMBO J. 30 2011 1302 1310
-
(2011)
EMBO J.
, vol.30
, pp. 1302-1310
-
-
Martinez-Rucobo, F.W.1
Sainsbury, S.2
Cheung, A.C.3
Cramer, P.4
-
60
-
-
79551663163
-
RNA polymerase and transcription elongation factor Spt4/5 complex structure
-
B.J. Klein, D. Bose, K.J. Baker, Z.M. Yusoff, X. Zhang, and K.S. Murakami RNA polymerase and transcription elongation factor Spt4/5 complex structure Proc. Natl. Acad. Sci. U. S. A. 108 2011 546 550
-
(2011)
Proc. Natl. Acad. Sci. U. S. A.
, vol.108
, pp. 546-550
-
-
Klein, B.J.1
Bose, D.2
Baker, K.J.3
Yusoff, Z.M.4
Zhang, X.5
Murakami, K.S.6
-
62
-
-
84937641334
-
Molecular basis of transcription-coupled pre-mRNA capping
-
F.W. Martinez-Rucobo, R. Kohler, M. van de Waterbeemd, A.J. Heck, M. Hemann, F. Herzog, H. Stark, and P. Cramer Molecular basis of transcription-coupled pre-mRNA capping Mol. Cell 58 2015 1079 1089
-
(2015)
Mol. Cell
, vol.58
, pp. 1079-1089
-
-
Martinez-Rucobo, F.W.1
Kohler, R.2
Van De Waterbeemd, M.3
Heck, A.J.4
Hemann, M.5
Herzog, F.6
Stark, H.7
Cramer, P.8
-
63
-
-
84923358406
-
Architecture of the RNA polymerase II-Mediator core initiation complex
-
C. Plaschka, L. Lariviere, L. Wenzeck, M. Seizl, M. Hemann, D. Tegunov, E.V. Petrotchenko, C.H. Borchers, W. Baumeister, F. Herzog, E. Villa, and P. Cramer Architecture of the RNA polymerase II-Mediator core initiation complex Nature 518 2015 376 380
-
(2015)
Nature
, vol.518
, pp. 376-380
-
-
Plaschka, C.1
Lariviere, L.2
Wenzeck, L.3
Seizl, M.4
Hemann, M.5
Tegunov, D.6
Petrotchenko, E.V.7
Borchers, C.H.8
Baumeister, W.9
Herzog, F.10
Villa, E.11
Cramer, P.12
-
64
-
-
84943784340
-
CDK7-dependent transcriptional addiction in triple-negative breast cancer
-
Y. Wang, T. Zhang, N. Kwiatkowski, B.J. Abraham, T.I. Lee, S. Xie, H. Yuzugullu, T. Von, H. Li, Z. Lin, D.G. Stover, E. Lim, Z.C. Wang, J.D. Iglehart, R.A. Young, N.S. Gray, and J.J. Zhao CDK7-dependent transcriptional addiction in triple-negative breast cancer Cell 163 2015 174 186
-
(2015)
Cell
, vol.163
, pp. 174-186
-
-
Wang, Y.1
Zhang, T.2
Kwiatkowski, N.3
Abraham, B.J.4
Lee, T.I.5
Xie, S.6
Yuzugullu, H.7
Von, T.8
Li, H.9
Lin, Z.10
Stover, D.G.11
Lim, E.12
Wang, Z.C.13
Iglehart, J.D.14
Young, R.A.15
Gray, N.S.16
Zhao, J.J.17
-
65
-
-
84919495606
-
Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor
-
C.L. Christensen, N. Kwiatkowski, B.J. Abraham, J. Carretero, F. Al-Shahrour, T. Zhang, E. Chipumuro, G.S. Herter-Sprie, E.A. Akbay, A. Altabef, J. Zhang, T. Shimamura, M. Capelletti, J.B. Reibel, J.D. Cavanaugh, P. Gao, Y. Liu, S.R. Michaelsen, H.S. Poulsen, A.R. Aref, D.A. Barbie, J.E. Bradner, R.E. George, N.S. Gray, R.A. Young, and K.K. Wong Targeting transcriptional addictions in small cell lung cancer with a covalent CDK7 inhibitor Cancer Cell 26 2014 909 922
-
(2014)
Cancer Cell
, vol.26
, pp. 909-922
-
-
Christensen, C.L.1
Kwiatkowski, N.2
Abraham, B.J.3
Carretero, J.4
Al-Shahrour, F.5
Zhang, T.6
Chipumuro, E.7
Herter-Sprie, G.S.8
Akbay, E.A.9
Altabef, A.10
Zhang, J.11
Shimamura, T.12
Capelletti, M.13
Reibel, J.B.14
Cavanaugh, J.D.15
Gao, P.16
Liu, Y.17
Michaelsen, S.R.18
Poulsen, H.S.19
Aref, A.R.20
Barbie, D.A.21
Bradner, J.E.22
George, R.E.23
Gray, N.S.24
Young, R.A.25
Wong, K.K.26
more..
-
66
-
-
84867010006
-
C-myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells
-
Z. Nie, G. Hu, G. Wei, K. Cui, A. Yamane, W. Resch, R. Wang, D.R. Green, L. Tessarollo, R. Casellas, K. Zhao, and D. Levens C-myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cells Cell 151 2012 68 79
-
(2012)
Cell
, vol.151
, pp. 68-79
-
-
Nie, Z.1
Hu, G.2
Wei, G.3
Cui, K.4
Yamane, A.5
Resch, W.6
Wang, R.7
Green, D.R.8
Tessarollo, L.9
Casellas, R.10
Zhao, K.11
Levens, D.12
-
67
-
-
84867021989
-
Transcriptional amplification in tumor cells with elevated c-myc
-
C.Y. Lin, J. Loven, P.B. Rahl, R.M. Paranal, C.B. Burge, J.E. Bradner, T.I. Lee, and R.A. Young Transcriptional amplification in tumor cells with elevated c-myc Cell 151 2012 56 67
-
(2012)
Cell
, vol.151
, pp. 56-67
-
-
Lin, C.Y.1
Loven, J.2
Rahl, P.B.3
Paranal, R.M.4
Burge, C.B.5
Bradner, J.E.6
Lee, T.I.7
Young, R.A.8
-
68
-
-
84883820687
-
Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels
-
M. Schuhmacher, and D. Eick Dose-dependent regulation of target gene expression and cell proliferation by c-Myc levels Transcription 4 2013 192 197
-
(2013)
Transcription
, vol.4
, pp. 192-197
-
-
Schuhmacher, M.1
Eick, D.2
-
69
-
-
84908473540
-
Cyclin-dependent kinases
-
M. Malumbres Cyclin-dependent kinases Genome Biol. 15 2014 122
-
(2014)
Genome Biol.
, vol.15
, pp. 122
-
-
Malumbres, M.1
-
70
-
-
84894118496
-
Erk1/2 activity promotes chromatin features and RNAPII phosphorylation at developmental promoters in mouse ESCs
-
W.W. Tee, S.S. Shen, O. Oksuz, V. Narendra, and D. Reinberg Erk1/2 activity promotes chromatin features and RNAPII phosphorylation at developmental promoters in mouse ESCs Cell 156 2014 678 690
-
(2014)
Cell
, vol.156
, pp. 678-690
-
-
Tee, W.W.1
Shen, S.S.2
Oksuz, O.3
Narendra, V.4
Reinberg, D.5
-
71
-
-
0033571245
-
Transcription-independent phosphorylation of the RNA polymerase II C-terminal domain (CTD) involves ERK kinases (MEK1/2)
-
F. Bonnet, M. Vigneron, O. Bensaude, and M.F. Dubois Transcription-independent phosphorylation of the RNA polymerase II C-terminal domain (CTD) involves ERK kinases (MEK1/2) Nucleic Acids Res. 27 1999 4399 4404
-
(1999)
Nucleic Acids Res.
, vol.27
, pp. 4399-4404
-
-
Bonnet, F.1
Vigneron, M.2
Bensaude, O.3
Dubois, M.F.4
-
72
-
-
0032549653
-
Characterization of the residues phosphorylated in vitro by different C-terminal domain kinases
-
S. Trigon, H. Serizawa, J.W. Conaway, R.C. Conaway, S.P. Jackson, and M. Morange Characterization of the residues phosphorylated in vitro by different C-terminal domain kinases J. Biol. Chem. 273 1998 6769 6775
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 6769-6775
-
-
Trigon, S.1
Serizawa, H.2
Conaway, J.W.3
Conaway, R.C.4
Jackson, S.P.5
Morange, M.6
-
73
-
-
0028099773
-
Enhanced phosphorylation of the C-terminal domain of RNA polymerase II upon serum stimulation of quiescent cells: Possible involvement of MAP kinases
-
M.F. Dubois, V.T. Nguyen, M.E. Dahmus, G. Pages, J. Pouyssegur, and O. Bensaude Enhanced phosphorylation of the C-terminal domain of RNA polymerase II upon serum stimulation of quiescent cells: possible involvement of MAP kinases EMBO J. 13 1994 4787 4797
-
(1994)
EMBO J.
, vol.13
, pp. 4787-4797
-
-
Dubois, M.F.1
Nguyen, V.T.2
Dahmus, M.E.3
Pages, G.4
Pouyssegur, J.5
Bensaude, O.6
-
74
-
-
84924902637
-
Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase
-
C. Di Vona, D. Bezdan, A.B. Islam, E. Salichs, N. Lopez-Bigas, S. Ossowski, and S. de la Luna Chromatin-wide profiling of DYRK1A reveals a role as a gene-specific RNA polymerase II CTD kinase Mol. Cell 57 2015 506 520
-
(2015)
Mol. Cell
, vol.57
, pp. 506-520
-
-
Di Vona, C.1
Bezdan, D.2
Islam, A.B.3
Salichs, E.4
Lopez-Bigas, N.5
Ossowski, S.6
De La Luna, S.7
-
75
-
-
84927912165
-
Vertebrate Ssu72 regulates and coordinates 3′-end formation of RNAs transcribed by RNA polymerase II
-
S. Wani, M. Yuda, Y. Fujiwara, M. Yamamoto, F. Harada, Y. Ohkuma, and Y. Hirose Vertebrate Ssu72 regulates and coordinates 3′-end formation of RNAs transcribed by RNA polymerase II PLoS One 9 2014 e106040
-
(2014)
PLoS One
, vol.9
-
-
Wani, S.1
Yuda, M.2
Fujiwara, Y.3
Yamamoto, M.4
Harada, F.5
Ohkuma, Y.6
Hirose, Y.7
-
76
-
-
84864831445
-
The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity
-
K. Xiang, J.L. Manley, and L. Tong The yeast regulator of transcription protein Rtr1 lacks an active site and phosphatase activity Nat. Commun. 3 2012 946
-
(2012)
Nat. Commun.
, vol.3
, pp. 946
-
-
Xiang, K.1
Manley, J.L.2
Tong, L.3
-
77
-
-
84904758006
-
Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD
-
P.L. Hsu, F. Yang, W. Smith-Kinnaman, W. Yang, J.E. Song, A.L. Mosley, and G. Varani Rtr1 is a dual specificity phosphatase that dephosphorylates Tyr1 and Ser5 on the RNA polymerase II CTD J. Mol. Biol. 426 2014 2970 2981
-
(2014)
J. Mol. Biol.
, vol.426
, pp. 2970-2981
-
-
Hsu, P.L.1
Yang, F.2
Smith-Kinnaman, W.3
Yang, W.4
Song, J.E.5
Mosley, A.L.6
Varani, G.7
-
78
-
-
84906101596
-
RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation
-
Z. Ni, C. Xu, X. Guo, G.O. Hunter, O.V. Kuznetsova, W. Tempel, E. Marcon, G. Zhong, H. Guo, W.H. Kuo, J. Li, P. Young, J.B. Olsen, C. Wan, P. Loppnau, M. El Bakkouri, G.A. Senisterra, H. He, H. Huang, S.S. Sidhu, A. Emili, S. Murphy, A.L. Mosley, C.H. Arrowsmith, J. Min, and J.F. Greenblatt RPRD1A and RPRD1B are human RNA polymerase II C-terminal domain scaffolds for Ser5 dephosphorylation Nat. Struct. Mol. Biol. 21 2014 686 695
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 686-695
-
-
Ni, Z.1
Xu, C.2
Guo, X.3
Hunter, G.O.4
Kuznetsova, O.V.5
Tempel, W.6
Marcon, E.7
Zhong, G.8
Guo, H.9
Kuo, W.H.10
Li, J.11
Young, P.12
Olsen, J.B.13
Wan, C.14
Loppnau, P.15
El Bakkouri, M.16
Senisterra, G.A.17
He, H.18
Huang, H.19
Sidhu, S.S.20
Emili, A.21
Murphy, S.22
Mosley, A.L.23
Arrowsmith, C.H.24
Min, J.25
Greenblatt, J.F.26
more..
-
79
-
-
84855880038
-
Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes
-
S. Egloff, J. Zaborowska, C. Laitem, T. Kiss, and S. Murphy Ser7 phosphorylation of the CTD recruits the RPAP2 Ser5 phosphatase to snRNA genes Mol. Cell 45 2012 111 122
-
(2012)
Mol. Cell
, vol.45
, pp. 111-122
-
-
Egloff, S.1
Zaborowska, J.2
Laitem, C.3
Kiss, T.4
Murphy, S.5
-
80
-
-
84901851275
-
The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae
-
W.R. Smith-Kinnaman, M.J. Berna, G.O. Hunter, J.D. True, P. Hsu, G.I. Cabello, M.J. Fox, G. Varani, and A.L. Mosley The interactome of the atypical phosphatase Rtr1 in Saccharomyces cerevisiae Mol. BioSyst. 10 2014 1730 1741
-
(2014)
Mol. BioSyst.
, vol.10
, pp. 1730-1741
-
-
Smith-Kinnaman, W.R.1
Berna, M.J.2
Hunter, G.O.3
True, J.D.4
Hsu, P.5
Cabello, G.I.6
Fox, M.J.7
Varani, G.8
Mosley, A.L.9
-
81
-
-
74949097227
-
Global identification of protein kinase substrates by protein microarray analysis
-
J. Mok, H. Im, and M. Snyder Global identification of protein kinase substrates by protein microarray analysis Nat. Protoc. 4 2009 1820 1827
-
(2009)
Nat. Protoc.
, vol.4
, pp. 1820-1827
-
-
Mok, J.1
Im, H.2
Snyder, M.3
-
82
-
-
79954507616
-
Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes
-
J. Fasolo, A. Sboner, M.G. Sun, H. Yu, R. Chen, D. Sharon, P.M. Kim, M. Gerstein, and M. Snyder Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes Genes Dev. 25 2011 767 778
-
(2011)
Genes Dev.
, vol.25
, pp. 767-778
-
-
Fasolo, J.1
Sboner, A.2
Sun, M.G.3
Yu, H.4
Chen, R.5
Sharon, D.6
Kim, P.M.7
Gerstein, M.8
Snyder, M.9
-
83
-
-
0032548846
-
Growth-related changes in phosphorylation of yeast RNA polymerase II
-
M. Patturajan, R.J. Schulte, B.M. Sefton, R. Berezney, M. Vincent, O. Bensaude, S.L. Warren, and J.L. Corden Growth-related changes in phosphorylation of yeast RNA polymerase II J. Biol. Chem. 273 1998 4689 4694
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 4689-4694
-
-
Patturajan, M.1
Schulte, R.J.2
Sefton, B.M.3
Berezney, R.4
Vincent, M.5
Bensaude, O.6
Warren, S.L.7
Corden, J.L.8
-
84
-
-
84908102120
-
A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation
-
Y. Chen, L. Zhang, C. Estaras, S.H. Choi, L. Moreno Jr.; J. Karn, J.J. Moresco, J.R. Yates 3rd, and K.A. Jones A gene-specific role for the Ssu72 RNAPII CTD phosphatase in HIV-1 Tat transactivation Genes Dev. 28 2014 2261 2275
-
(2014)
Genes Dev.
, vol.28
, pp. 2261-2275
-
-
Chen, Y.1
Zhang, L.2
Estaras, C.3
Choi, S.H.4
Moreno, L.5
Karn, J.6
Moresco, J.J.7
Yates, J.R.8
Jones, K.A.9
-
85
-
-
33646804554
-
Bur1/Bur2 and the Ctk complex in yeast: The split personality of mammalian P-TEFb
-
A. Wood, and A. Shilatifard Bur1/Bur2 and the Ctk complex in yeast: the split personality of mammalian P-TEFb Cell Cycle 5 2006 1066 1068
-
(2006)
Cell Cycle
, vol.5
, pp. 1066-1068
-
-
Wood, A.1
Shilatifard, A.2
-
86
-
-
77958587420
-
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
-
B. Bartkowiak, P. Liu, H.P. Phatnani, N.J. Fuda, J.J. Cooper, D.H. Price, K. Adelman, J.T. Lis, and A.L. Greenleaf CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1 Genes Dev. 24 2010 2303 2316
-
(2010)
Genes Dev.
, vol.24
, pp. 2303-2316
-
-
Bartkowiak, B.1
Liu, P.2
Phatnani, H.P.3
Fuda, N.J.4
Cooper, J.J.5
Price, D.H.6
Adelman, K.7
Lis, J.T.8
Greenleaf, A.L.9
-
87
-
-
80054756087
-
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
-
D. Blazek, J. Kohoutek, K. Bartholomeeusen, E. Johansen, P. Hulinkova, Z. Luo, P. Cimermancic, J. Ule, and B.M. Peterlin The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes Genes Dev. 25 2011 2158 2172
-
(2011)
Genes Dev.
, vol.25
, pp. 2158-2172
-
-
Blazek, D.1
Kohoutek, J.2
Bartholomeeusen, K.3
Johansen, E.4
Hulinkova, P.5
Luo, Z.6
Cimermancic, P.7
Ule, J.8
Peterlin, B.M.9
-
88
-
-
84860832960
-
BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain
-
B.N. Devaiah, B.A. Lewis, N. Cherman, M.C. Hewitt, B.K. Albrecht, P.G. Robey, K. Ozato, R.J. Sims 3rd, and D.S. Singer BRD4 is an atypical kinase that phosphorylates serine2 of the RNA polymerase II carboxy-terminal domain Proc. Natl. Acad. Sci. U. S. A. 109 2012 6927 6932
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 6927-6932
-
-
Devaiah, B.N.1
Lewis, B.A.2
Cherman, N.3
Hewitt, M.C.4
Albrecht, B.K.5
Robey, P.G.6
Ozato, K.7
Sims, R.J.8
Singer, D.S.9
-
89
-
-
79958729004
-
Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb?
-
B. Bartkowiak, and A.L. Greenleaf Phosphorylation of RNAPII: To P-TEFb or not to P-TEFb? Transcription 2 2011 115 119
-
(2011)
Transcription
, vol.2
, pp. 115-119
-
-
Bartkowiak, B.1
Greenleaf, A.L.2
-
90
-
-
84876276025
-
In vivo live imaging of RNA polymerase II transcription factories in primary cells
-
A. Ghamari, M.P. van de Corput, S. Thongjuea, W.A. van Cappellen, W. van Ijcken, J. van Haren, E. Soler, D. Eick, B. Lenhard, and F.G. Grosveld In vivo live imaging of RNA polymerase II transcription factories in primary cells Genes Dev. 27 2013 767 777
-
(2013)
Genes Dev.
, vol.27
, pp. 767-777
-
-
Ghamari, A.1
Van De Corput, M.P.2
Thongjuea, S.3
Van Cappellen, W.A.4
Van Ijcken, W.5
Van Haren, J.6
Soler, E.7
Eick, D.8
Lenhard, B.9
Grosveld, F.G.10
-
91
-
-
62549104640
-
Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters
-
H. Qiu, C. Hu, and A.G. Hinnebusch Phosphorylation of the Pol II CTD by KIN28 enhances BUR1/BUR2 recruitment and Ser2 CTD phosphorylation near promoters Mol. Cell 33 2009 752 762
-
(2009)
Mol. Cell
, vol.33
, pp. 752-762
-
-
Qiu, H.1
Hu, C.2
Hinnebusch, A.G.3
-
92
-
-
84893936668
-
3′ End formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells
-
L. Davidson, L. Muniz, and S. West 3′ End formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells Genes Dev. 28 2014 342 356
-
(2014)
Genes Dev.
, vol.28
, pp. 342-356
-
-
Davidson, L.1
Muniz, L.2
West, S.3
-
93
-
-
84881601434
-
Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. Elegans germline
-
E.A. Bowman, C.R. Bowman, J.H. Ahn, and W.G. Kelly Phosphorylation of RNA polymerase II is independent of P-TEFb in the C. elegans germline Development 140 2013 3703 3713
-
(2013)
Development
, vol.140
, pp. 3703-3713
-
-
Bowman, E.A.1
Bowman, C.R.2
Ahn, J.H.3
Kelly, W.G.4
-
94
-
-
84868681176
-
Interaction of cyclin-dependent kinase 12/CrkRS with Cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II
-
S.W. Cheng, M.A. Kuzyk, A. Moradian, T.A. Ichu, V.C. Chang, J.F. Tien, S.E. Vollett, M. Griffith, M.A. Marra, and G.B. Morin Interaction of cyclin-dependent kinase 12/CrkRS with Cyclin K1 is required for the phosphorylation of the C-terminal domain of RNA polymerase II Mol. Cell. Biol. 32 2012 4691 4704
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 4691-4704
-
-
Cheng, S.W.1
Kuzyk, M.A.2
Moradian, A.3
Ichu, T.A.4
Chang, V.C.5
Tien, J.F.6
Vollett, S.E.7
Griffith, M.8
Marra, M.A.9
Morin, G.B.10
-
95
-
-
84923196896
-
Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing
-
K. Liang, X. Gao, J.M. Gilmore, L. Florens, M.P. Washburn, E. Smith, and A. Shilatifard Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing Mol. Cell. Biol. 35 2015 928 938
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 928-938
-
-
Liang, K.1
Gao, X.2
Gilmore, J.M.3
Florens, L.4
Washburn, M.P.5
Smith, E.6
Shilatifard, A.7
-
96
-
-
84904343427
-
The structure and substrate specificity of human Cdk12/Cyclin K
-
C.A. Bosken, L. Farnung, C. Hintermair, M. Merzel Schachter, K. Vogel-Bachmayr, D. Blazek, K. Anand, R.P. Fisher, D. Eick, and M. Geyer The structure and substrate specificity of human Cdk12/Cyclin K Nat. Commun. 5 2014 3505
-
(2014)
Nat. Commun.
, vol.5
, pp. 3505
-
-
Bosken, C.A.1
Farnung, L.2
Hintermair, C.3
Merzel Schachter, M.4
Vogel-Bachmayr, K.5
Blazek, D.6
Anand, K.7
Fisher, R.P.8
Eick, D.9
Geyer, M.10
-
97
-
-
84922118253
-
Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex
-
B. Bartkowiak, and A.L. Greenleaf Expression, purification, and identification of associated proteins of the full-length hCDK12/CyclinK complex J. Biol. Chem. 290 2015 1786 1795
-
(2015)
J. Biol. Chem.
, vol.290
, pp. 1786-1795
-
-
Bartkowiak, B.1
Greenleaf, A.L.2
-
98
-
-
2942528748
-
C-terminal repeat domain kinase i phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats
-
J.C. Jones, H.P. Phatnani, T.A. Haystead, J.A. MacDonald, S.M. Alam, and A.L. Greenleaf C-terminal repeat domain kinase I phosphorylates Ser2 and Ser5 of RNA polymerase II C-terminal domain repeats J. Biol. Chem. 279 2004 24957 24964
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 24957-24964
-
-
Jones, J.C.1
Phatnani, H.P.2
Haystead, T.A.3
MacDonald, J.A.4
Alam, S.M.5
Greenleaf, A.L.6
-
99
-
-
84864293829
-
Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition
-
N. Czudnochowski, C.A. Bosken, and M. Geyer Serine-7 but not serine-5 phosphorylation primes RNA polymerase II CTD for P-TEFb recognition Nat. Commun. 3 2012 842
-
(2012)
Nat. Commun.
, vol.3
, pp. 842
-
-
Czudnochowski, N.1
Bosken, C.A.2
Geyer, M.3
-
100
-
-
84938149922
-
Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas
-
B. Bartkowiak, C. Yan, and A.L. Greenleaf Engineering an analog-sensitive CDK12 cell line using CRISPR/Cas Biochim. Biophys. Acta 1849 2015 1179 1187
-
(2015)
Biochim. Biophys. Acta
, vol.1849
, pp. 1179-1187
-
-
Bartkowiak, B.1
Yan, C.2
Greenleaf, A.L.3
-
101
-
-
84919665147
-
Cyclin-dependent kinase 12 increases 3′ end processing of growth factor-induced c-FOS transcripts
-
T.T. Eifler, W. Shao, K. Bartholomeeusen, K. Fujinaga, S. Jager, J.R. Johnson, Z. Luo, N.J. Krogan, and B.M. Peterlin Cyclin-dependent kinase 12 increases 3′ end processing of growth factor-induced c-FOS transcripts Mol. Cell. Biol. 35 2015 468 478
-
(2015)
Mol. Cell. Biol.
, vol.35
, pp. 468-478
-
-
Eifler, T.T.1
Shao, W.2
Bartholomeeusen, K.3
Fujinaga, K.4
Jager, S.5
Johnson, J.R.6
Luo, Z.7
Krogan, N.J.8
Peterlin, B.M.9
-
102
-
-
84937622540
-
Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex
-
K.M. Ekumi, H. Paculova, T. Lenasi, V. Pospichalova, C.A. Bosken, J. Rybarikova, V. Bryja, M. Geyer, D. Blazek, and M. Barboric Ovarian carcinoma CDK12 mutations misregulate expression of DNA repair genes via deficient formation and function of the Cdk12/CycK complex Nucleic Acids Res. 43 2015 2575 2589
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 2575-2589
-
-
Ekumi, K.M.1
Paculova, H.2
Lenasi, T.3
Pospichalova, V.4
Bosken, C.A.5
Rybarikova, J.6
Bryja, V.7
Geyer, M.8
Blazek, D.9
Barboric, M.10
-
103
-
-
84897457200
-
Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors
-
P.M. Joshi, S.L. Sutor, C.J. Huntoon, and L.M. Karnitz Ovarian cancer-associated mutations disable catalytic activity of CDK12, a kinase that promotes homologous recombination repair and resistance to cisplatin and poly(ADP-ribose) polymerase inhibitors J. Biol. Chem. 289 2014 9247 9253
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 9247-9253
-
-
Joshi, P.M.1
Sutor, S.L.2
Huntoon, C.J.3
Karnitz, L.M.4
-
104
-
-
33645214031
-
Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation
-
H.H. Chen, Y.C. Wang, and M.J. Fann Identification and characterization of the CDK12/cyclin L1 complex involved in alternative splicing regulation Mol. Cell. Biol. 26 2006 2736 2745
-
(2006)
Mol. Cell. Biol.
, vol.26
, pp. 2736-2745
-
-
Chen, H.H.1
Wang, Y.C.2
Fann, M.J.3
-
105
-
-
0034896206
-
CrkRS: A novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles
-
T.K. Ko, E. Kelly, and J. Pines CrkRS: a novel conserved Cdc2-related protein kinase that colocalises with SC35 speckles J. Cell Sci. 114 2001 2591 2603
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2591-2603
-
-
Ko, T.K.1
Kelly, E.2
Pines, J.3
-
106
-
-
84900509678
-
Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells
-
N. Descostes, M. Heidemann, L. Spinelli, R. Schuller, M.A. Maqbool, R. Fenouil, F. Koch, C. Innocenti, M. Gut, I. Gut, D. Eick, and J.C. Andrau Tyrosine phosphorylation of RNA polymerase II CTD is associated with antisense promoter transcription and active enhancers in mammalian cells Elife 3 2014 e02105
-
(2014)
Elife
, vol.3
-
-
Descostes, N.1
Heidemann, M.2
Spinelli, L.3
Schuller, R.4
Maqbool, M.A.5
Fenouil, R.6
Koch, F.7
Innocenti, C.8
Gut, M.9
Gut, I.10
Eick, D.11
Andrau, J.C.12
-
107
-
-
84900486090
-
RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells
-
J.P. Hsin, W. Li, M. Hoque, B. Tian, and J.L. Manley RNAP II CTD tyrosine 1 performs diverse functions in vertebrate cells Elife 3 2014 e02112
-
(2014)
Elife
, vol.3
-
-
Hsin, J.P.1
Li, W.2
Hoque, M.3
Tian, B.4
Manley, J.L.5
-
108
-
-
84862977456
-
CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II
-
A. Mayer, M. Heidemann, M. Lidschreiber, A. Schreieck, M. Sun, C. Hintermair, E. Kremmer, D. Eick, and P. Cramer CTD tyrosine phosphorylation impairs termination factor recruitment to RNA polymerase II Science 336 2012 1723 1725
-
(2012)
Science
, vol.336
, pp. 1723-1725
-
-
Mayer, A.1
Heidemann, M.2
Lidschreiber, M.3
Schreieck, A.4
Sun, M.5
Hintermair, C.6
Kremmer, E.7
Eick, D.8
Cramer, P.9
-
109
-
-
0030795331
-
Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product
-
R. Baskaran, G.G. Chiang, T. Mysliwiec, G.D. Kruh, and J.Y. Wang Tyrosine phosphorylation of RNA polymerase II carboxyl-terminal domain by the Abl-related gene product J. Biol. Chem. 272 1997 18905 18909
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 18905-18909
-
-
Baskaran, R.1
Chiang, G.G.2
Mysliwiec, T.3
Kruh, G.D.4
Wang, J.Y.5
-
110
-
-
0033022183
-
Nuclear c-Abl is a COOH-terminal repeated domain (CTD)-tyrosine (CTD)-tyrosine kinase-specific for the mammalian RNA polymerase II: Possible role in transcription elongation
-
R. Baskaran, S.R. Escobar, and J.Y. Wang Nuclear c-Abl is a COOH-terminal repeated domain (CTD)-tyrosine (CTD)-tyrosine kinase-specific for the mammalian RNA polymerase II: possible role in transcription elongation Cell Growth Differ. 10 1999 387 396
-
(1999)
Cell Growth Differ.
, vol.10
, pp. 387-396
-
-
Baskaran, R.1
Escobar, S.R.2
Wang, J.Y.3
-
111
-
-
84893810594
-
RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7
-
A. Schreieck, A.D. Easter, S. Etzold, K. Wiederhold, M. Lidschreiber, P. Cramer, and L.A. Passmore RNA polymerase II termination involves C-terminal-domain tyrosine dephosphorylation by CPF subunit Glc7 Nat. Struct. Mol. Biol. 21 2014 175 179
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 175-179
-
-
Schreieck, A.1
Easter, A.D.2
Etzold, S.3
Wiederhold, K.4
Lidschreiber, M.5
Cramer, P.6
Passmore, L.A.7
-
112
-
-
84863229897
-
Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination
-
D.W. Zhang, A.L. Mosley, S.R. Ramisetty, J.B. Rodriguez-Molina, M.P. Washburn, and A.Z. Ansari Ssu72 phosphatase-dependent erasure of phospho-Ser7 marks on the RNA polymerase II C-terminal domain is essential for viability and transcription termination J. Biol. Chem. 287 2012 8541 8551
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 8541-8551
-
-
Zhang, D.W.1
Mosley, A.L.2
Ramisetty, S.R.3
Rodriguez-Molina, J.B.4
Washburn, M.P.5
Ansari, A.Z.6
-
113
-
-
2342533807
-
Ssu72 Is an RNA polymerase II CTD phosphatase
-
S. Krishnamurthy, X. He, M. Reyes-Reyes, C. Moore, and M. Hampsey Ssu72 Is an RNA polymerase II CTD phosphatase Mol. Cell 14 2004 387 394
-
(2004)
Mol. Cell
, vol.14
, pp. 387-394
-
-
Krishnamurthy, S.1
He, X.2
Reyes-Reyes, M.3
Moore, C.4
Hampsey, M.5
-
114
-
-
84929161687
-
CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes
-
C. Laitem, J. Zaborowska, N.F. Isa, J. Kufs, M. Dienstbier, and S. Murphy CDK9 inhibitors define elongation checkpoints at both ends of RNA polymerase II-transcribed genes Nat. Struct. Mol. Biol. 22 2015 396 403
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 396-403
-
-
Laitem, C.1
Zaborowska, J.2
Isa, N.F.3
Kufs, J.4
Dienstbier, M.5
Murphy, S.6
-
115
-
-
84894318075
-
Coupling mRNA processing with transcription in time and space
-
D.L. Bentley Coupling mRNA processing with transcription in time and space Nat. Rev. Genet. 15 2014 163 175
-
(2014)
Nat. Rev. Genet.
, vol.15
, pp. 163-175
-
-
Bentley, D.L.1
-
116
-
-
84867160564
-
The RNA polymerase II CTD coordinates transcription and RNA processing
-
J.P. Hsin, and J.L. Manley The RNA polymerase II CTD coordinates transcription and RNA processing Genes Dev. 26 2012 2119 2137
-
(2012)
Genes Dev.
, vol.26
, pp. 2119-2137
-
-
Hsin, J.P.1
Manley, J.L.2
-
117
-
-
0033105827
-
Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme
-
C.K. Ho, and S. Shuman Distinct roles for CTD Ser-2 and Ser-5 phosphorylation in the recruitment and allosteric activation of mammalian mRNA capping enzyme Mol. Cell 3 1999 405 411
-
(1999)
Mol. Cell
, vol.3
, pp. 405-411
-
-
Ho, C.K.1
Shuman, S.2
-
118
-
-
15644372864
-
5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II
-
S. McCracken, N. Fong, E. Rosonina, K. Yankulov, G. Brothers, D. Siderovski, A. Hessel, S. Foster, S. Shuman, and D.L. Bentley 5′-Capping enzymes are targeted to pre-mRNA by binding to the phosphorylated carboxy-terminal domain of RNA polymerase II Genes Dev. 11 1997 3306 3318
-
(1997)
Genes Dev.
, vol.11
, pp. 3306-3318
-
-
McCracken, S.1
Fong, N.2
Rosonina, E.3
Yankulov, K.4
Brothers, G.5
Siderovski, D.6
Hessel, A.7
Foster, S.8
Shuman, S.9
Bentley, D.L.10
-
119
-
-
0031453408
-
mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain
-
E.J. Cho, T. Takagi, C.R. Moore, and S. Buratowski mRNA capping enzyme is recruited to the transcription complex by phosphorylation of the RNA polymerase II carboxy-terminal domain Genes Dev. 11 1997 3319 3326
-
(1997)
Genes Dev.
, vol.11
, pp. 3319-3326
-
-
Cho, E.J.1
Takagi, T.2
Moore, C.R.3
Buratowski, S.4
-
120
-
-
0035958863
-
The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes
-
Y. Pei, S. Hausmann, C.K. Ho, B. Schwer, and S. Shuman The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes J. Biol. Chem. 276 2001 28075 28082
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 28075-28082
-
-
Pei, Y.1
Hausmann, S.2
Ho, C.K.3
Schwer, B.4
Shuman, S.5
-
121
-
-
84902519559
-
How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes
-
S.K. Doamekpor, A.M. Sanchez, B. Schwer, S. Shuman, and C.D. Lima How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes Genes Dev. 28 2014 1323 1336
-
(2014)
Genes Dev.
, vol.28
, pp. 1323-1336
-
-
Doamekpor, S.K.1
Sanchez, A.M.2
Schwer, B.3
Shuman, S.4
Lima, C.D.5
-
122
-
-
0038094496
-
Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II
-
C. Fabrega, V. Shen, S. Shuman, and C.D. Lima Structure of an mRNA capping enzyme bound to the phosphorylated carboxy-terminal domain of RNA polymerase II Mol. Cell 11 2003 1549 1561
-
(2003)
Mol. Cell
, vol.11
, pp. 1549-1561
-
-
Fabrega, C.1
Shen, V.2
Shuman, S.3
Lima, C.D.4
-
123
-
-
84950160968
-
Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification
-
J. Mbogning, V. Page, J. Burston, E. Schwenger, R.P. Fisher, B. Schwer, S. Shuman, and J.C. Tanny Functional interaction of Rpb1 and Spt5 C-terminal domains in co-transcriptional histone modification Nucleic Acids Res. 43 2015 9766 9775
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 9766-9775
-
-
Mbogning, J.1
Page, V.2
Burston, J.3
Schwenger, E.4
Fisher, R.P.5
Schwer, B.6
Shuman, S.7
Tanny, J.C.8
-
124
-
-
84864015492
-
Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition
-
C.V. St Amour, M. Sanso, C.A. Bosken, K.M. Lee, S. Larochelle, C. Zhang, K.M. Shokat, M. Geyer, and R.P. Fisher Separate domains of fission yeast Cdk9 (P-TEFb) are required for capping enzyme recruitment and primed (Ser7-phosphorylated) Rpb1 carboxyl-terminal domain substrate recognition Mol. Cell. Biol. 32 2012 2372 2383
-
(2012)
Mol. Cell. Biol.
, vol.32
, pp. 2372-2383
-
-
Amour, C.V.S.1
Sanso, M.2
Bosken, C.A.3
Lee, K.M.4
Larochelle, S.5
Zhang, C.6
Shokat, K.M.7
Geyer, M.8
Fisher, R.P.9
-
125
-
-
2442681755
-
Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II
-
S.S. Mandal, C. Chu, T. Wada, H. Handa, A.J. Shatkin, and D. Reinberg Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase II Proc. Natl. Acad. Sci. U. S. A. 101 2004 7572 7577
-
(2004)
Proc. Natl. Acad. Sci. U. S. A.
, vol.101
, pp. 7572-7577
-
-
Mandal, S.S.1
Chu, C.2
Wada, T.3
Handa, H.4
Shatkin, A.J.5
Reinberg, D.6
-
126
-
-
0037470160
-
Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control
-
Y. Pei, B. Schwer, and S. Shuman Interactions between fission yeast Cdk9, its cyclin partner Pch1, and mRNA capping enzyme Pct1 suggest an elongation checkpoint for mRNA quality control J. Biol. Chem. 278 2003 7180 7188
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 7180-7188
-
-
Pei, Y.1
Schwer, B.2
Shuman, S.3
-
127
-
-
1542290655
-
Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes
-
M. Kim, S.H. Ahn, N.J. Krogan, J.F. Greenblatt, and S. Buratowski Transitions in RNA polymerase II elongation complexes at the 3′ ends of genes EMBO J. 23 2004 354 364
-
(2004)
EMBO J.
, vol.23
, pp. 354-364
-
-
Kim, M.1
Ahn, S.H.2
Krogan, N.J.3
Greenblatt, J.F.4
Buratowski, S.5
-
128
-
-
84888240103
-
Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II
-
D.M. Meinel, C. Burkert-Kautzsch, A. Kieser, E. O'Duibhir, M. Siebert, A. Mayer, P. Cramer, J. Soding, F.C. Holstege, and K. Strasser Recruitment of TREX to the transcription machinery by its direct binding to the phospho-CTD of RNA polymerase II PLoS Genet. 9 2013 e1003914
-
(2013)
PLoS Genet.
, vol.9
-
-
Meinel, D.M.1
Burkert-Kautzsch, C.2
Kieser, A.3
O'Duibhir, E.4
Siebert, M.5
Mayer, A.6
Cramer, P.7
Soding, J.8
Holstege, F.C.9
Strasser, K.10
-
129
-
-
84864577725
-
Dynamic transitions in RNA polymerase II density profiles during transcription termination
-
A.R. Grosso, S.F. de Almeida, J. Braga, and M. Carmo-Fonseca Dynamic transitions in RNA polymerase II density profiles during transcription termination Genome Res. 22 2012 1447 1456
-
(2012)
Genome Res.
, vol.22
, pp. 1447-1456
-
-
Grosso, A.R.1
De Almeida, S.F.2
Braga, J.3
Carmo-Fonseca, M.4
-
130
-
-
84862206497
-
Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation
-
C. Hintermair, M. Heidemann, F. Koch, N. Descostes, M. Gut, I. Gut, R. Fenouil, P. Ferrier, A. Flatley, E. Kremmer, R.D. Chapman, J.C. Andrau, and D. Eick Threonine-4 of mammalian RNA polymerase II CTD is targeted by Polo-like kinase 3 and required for transcriptional elongation EMBO J. 31 2012 2784 2797
-
(2012)
EMBO J.
, vol.31
, pp. 2784-2797
-
-
Hintermair, C.1
Heidemann, M.2
Koch, F.3
Descostes, N.4
Gut, M.5
Gut, I.6
Fenouil, R.7
Ferrier, P.8
Flatley, A.9
Kremmer, E.10
Chapman, R.D.11
Andrau, J.C.12
Eick, D.13
-
131
-
-
84856756676
-
Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs
-
E. Brookes, I. de Santiago, D. Hebenstreit, K.J. Morris, T. Carroll, S.Q. Xie, J.K. Stock, M. Heidemann, D. Eick, N. Nozaki, H. Kimura, J. Ragoussis, S.A. Teichmann, and A. Pombo Polycomb associates genome-wide with a specific RNA polymerase II variant, and regulates metabolic genes in ESCs Cell Stem Cell 10 2012 157 170
-
(2012)
Cell Stem Cell
, vol.10
, pp. 157-170
-
-
Brookes, E.1
De Santiago, I.2
Hebenstreit, D.3
Morris, K.J.4
Carroll, T.5
Xie, S.Q.6
Stock, J.K.7
Heidemann, M.8
Eick, D.9
Nozaki, N.10
Kimura, H.11
Ragoussis, J.12
Teichmann, S.A.13
Pombo, A.14
-
132
-
-
77951920690
-
C-Myc regulates transcriptional pause release
-
P.B. Rahl, C.Y. Lin, A.C. Seila, R.A. Flynn, S. McCuine, C.B. Burge, P.A. Sharp, and R.A. Young c-Myc regulates transcriptional pause release Cell 141 2010 432 445
-
(2010)
Cell
, vol.141
, pp. 432-445
-
-
Rahl, P.B.1
Lin, C.Y.2
Seila, A.C.3
Flynn, R.A.4
McCuine, S.5
Burge, C.B.6
Sharp, P.A.7
Young, R.A.8
-
133
-
-
37849036555
-
RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes
-
K. Glover-Cutter, S. Kim, J. Espinosa, and D.L. Bentley RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes Nat. Struct. Mol. Biol. 15 2008 71 78
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 71-78
-
-
Glover-Cutter, K.1
Kim, S.2
Espinosa, J.3
Bentley, D.L.4
-
134
-
-
84927710816
-
Pcf11 orchestrates transcription termination pathways in yeast
-
P. Grzechnik, M.R. Gdula, and N.J. Proudfoot Pcf11 orchestrates transcription termination pathways in yeast Genes Dev. 29 2015 849 861
-
(2015)
Genes Dev.
, vol.29
, pp. 849-861
-
-
Grzechnik, P.1
Gdula, M.R.2
Proudfoot, N.J.3
-
135
-
-
49449110180
-
The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain
-
L. Vasiljeva, M. Kim, H. Mutschler, S. Buratowski, and A. Meinhart The Nrd1-Nab3-Sen1 termination complex interacts with the Ser5-phosphorylated RNA polymerase II C-terminal domain Nat. Struct. Mol. Biol. 15 2008 795 804
-
(2008)
Nat. Struct. Mol. Biol.
, vol.15
, pp. 795-804
-
-
Vasiljeva, L.1
Kim, M.2
Mutschler, H.3
Buratowski, S.4
Meinhart, A.5
-
136
-
-
84891895641
-
The role of Ctk1 kinase in termination of small non-coding RNAs
-
T.L. Lenstra, A. Tudek, S. Clauder, Z. Xu, S.T. Pachis, D. van Leenen, P. Kemmeren, L.M. Steinmetz, D. Libri, and F.C. Holstege The role of Ctk1 kinase in termination of small non-coding RNAs PLoS One 8 2013 e80495
-
(2013)
PLoS One
, vol.8
-
-
Lenstra, T.L.1
Tudek, A.2
Clauder, S.3
Xu, Z.4
Pachis, S.T.5
Van Leenen, D.6
Kemmeren, P.7
Steinmetz, L.M.8
Libri, D.9
Holstege, F.C.10
-
137
-
-
84871889392
-
Effects of the Paf1 complex and histone modifications on snoRNA 3′-end formation reveal broad and locus-specific regulation
-
B.N. Tomson, E.M. Crisucci, L.E. Heisler, M. Gebbia, C. Nislow, and K.M. Arndt Effects of the Paf1 complex and histone modifications on snoRNA 3′-end formation reveal broad and locus-specific regulation Mol. Cell. Biol. 33 2013 170 182
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 170-182
-
-
Tomson, B.N.1
Crisucci, E.M.2
Heisler, L.E.3
Gebbia, M.4
Nislow, C.5
Arndt, K.M.6
-
138
-
-
0035921929
-
RNA-binding protein Nrd1 directs poly(A)-independent 3′-end formation of RNA polymerase II transcripts
-
E.J. Steinmetz, N.K. Conrad, D.A. Brow, and J.L. Corden RNA-binding protein Nrd1 directs poly(A)-independent 3′-end formation of RNA polymerase II transcripts Nature 413 2001 327 331
-
(2001)
Nature
, vol.413
, pp. 327-331
-
-
Steinmetz, E.J.1
Conrad, N.K.2
Brow, D.A.3
Corden, J.L.4
-
139
-
-
84896534805
-
Rat1p maintains RNA polymerase II CTD phosphorylation balance
-
S. Jimeno-Gonzalez, M. Schmid, F. Malagon, L.L. Haaning, and T.H. Jensen Rat1p maintains RNA polymerase II CTD phosphorylation balance RNA 20 2014 551 558
-
(2014)
RNA
, vol.20
, pp. 551-558
-
-
Jimeno-Gonzalez, S.1
Schmid, M.2
Malagon, F.3
Haaning, L.L.4
Jensen, T.H.5
-
140
-
-
84949009421
-
Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD
-
M. Koga, M. Hayashi, and D. Kaida Splicing inhibition decreases phosphorylation level of Ser2 in Pol II CTD Nucleic Acids Res. 43 2015 8258 8267
-
(2015)
Nucleic Acids Res.
, vol.43
, pp. 8258-8267
-
-
Koga, M.1
Hayashi, M.2
Kaida, D.3
-
141
-
-
80555125095
-
RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3′ end processing
-
J.P. Hsin, A. Sheth, and J.L. Manley RNAP II CTD phosphorylated on threonine-4 is required for histone mRNA 3′ end processing Science 334 2011 683 686
-
(2011)
Science
, vol.334
, pp. 683-686
-
-
Hsin, J.P.1
Sheth, A.2
Manley, J.L.3
-
142
-
-
79960455840
-
Deciphering the RNA polymerase II CTD code in fission yeast
-
B. Schwer, and S. Shuman Deciphering the RNA polymerase II CTD code in fission yeast Mol. Cell 43 2011 311 318
-
(2011)
Mol. Cell
, vol.43
, pp. 311-318
-
-
Schwer, B.1
Shuman, S.2
-
143
-
-
1242309371
-
The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability
-
R.D. Chapman, B. Palancade, A. Lang, O. Bensaude, and D. Eick The last CTD repeat of the mammalian RNA polymerase II large subunit is important for its stability Nucleic Acids Res. 32 2004 35 44
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 35-44
-
-
Chapman, R.D.1
Palancade, B.2
Lang, A.3
Bensaude, O.4
Eick, D.5
-
144
-
-
84946600980
-
The RNAPII-CTD maintains genome integrity through inhibition of retrotransposon gene expression and transposition
-
M.J. Aristizabal, G.L. Negri, and M.S. Kobor The RNAPII-CTD maintains genome integrity through inhibition of retrotransposon gene expression and transposition PLoS Genet. 11 2015 e1005608
-
(2015)
PLoS Genet.
, vol.11
-
-
Aristizabal, M.J.1
Negri, G.L.2
Kobor, M.S.3
-
145
-
-
84937441977
-
Promoter nucleosome dynamics regulated by signalling through the CTD code
-
P. Materne, J. Anandhakumar, V. Migeot, I. Soriano, C. Yague-Sanz, E. Hidalgo, C. Mignion, L. Quintales, F. Antequera, and D. Hermand Promoter nucleosome dynamics regulated by signalling through the CTD code Elife 4 2015 e09008
-
(2015)
Elife
, vol.4
-
-
Materne, P.1
Anandhakumar, J.2
Migeot, V.3
Soriano, I.4
Yague-Sanz, C.5
Hidalgo, E.6
Mignion, C.7
Quintales, L.8
Antequera, F.9
Hermand, D.10
-
146
-
-
84896497914
-
Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast
-
B. Schwer, D.A. Bitton, A.M. Sanchez, J. Bahler, and S. Shuman Individual letters of the RNA polymerase II CTD code govern distinct gene expression programs in fission yeast Proc. Natl. Acad. Sci. U. S. A. 111 2014 4185 4190
-
(2014)
Proc. Natl. Acad. Sci. U. S. A.
, vol.111
, pp. 4185-4190
-
-
Schwer, B.1
Bitton, D.A.2
Sanchez, A.M.3
Bahler, J.4
Shuman, S.5
|