-
1
-
-
0037032835
-
The protein kinase complement of the human genome
-
Manning G, Whyte DB, Martinez R, Hunter T, Sudarsanam S: The protein kinase complement of the human genome. Science 2002, 298:1912-1934.
-
(2002)
Science
, vol.298
, pp. 1912-1934
-
-
Manning, G.1
Whyte, D.B.2
Martinez, R.3
Hunter, T.4
Sudarsanam, S.5
-
2
-
-
71049169616
-
Cyclin-dependent kinases: a family portrait
-
Malumbres M, Harlow E, Hunt T, Hunter T, Lahti JM, Manning G, Morgan DO, Tsai LH, Wolgemuth DJ: Cyclin-dependent kinases: a family portrait. Nat Cell Biol 2009, 11:1275-1276.
-
(2009)
Nat Cell Biol
, vol.11
, pp. 1275-1276
-
-
Malumbres, M.1
Harlow, E.2
Hunt, T.3
Hunter, T.4
Lahti, J.M.5
Manning, G.6
Morgan, D.O.7
Tsai, L.H.8
Wolgemuth, D.J.9
-
4
-
-
0031466305
-
Cyclin-dependent kinases: engines, clocks, and microprocessors
-
Morgan DO: Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 1997, 13:261-291.
-
(1997)
Annu Rev Cell Dev Biol
, vol.13
, pp. 261-291
-
-
Morgan, D.O.1
-
5
-
-
84880264045
-
Cdks, cyclins and CKIs: roles beyond cell cycle regulation
-
Lim S, Kaldis P: Cdks, cyclins and CKIs: roles beyond cell cycle regulation. Development 2013, 140:3079-3093.
-
(2013)
Development
, vol.140
, pp. 3079-3093
-
-
Lim, S.1
Kaldis, P.2
-
6
-
-
60749109846
-
Cell cycle, CDKs and cancer: a changing paradigm
-
Malumbres M, Barbacid M: Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009, 9:153-166.
-
(2009)
Nat Rev Cancer
, vol.9
, pp. 153-166
-
-
Malumbres, M.1
Barbacid, M.2
-
7
-
-
84892470353
-
Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages
-
Cao L, Chen F, Yang X, Xu W, Xie J, Yu L: Phylogenetic analysis of CDK and cyclin proteins in premetazoan lineages. BMC Evol Biol 2014, 14:10.
-
(2014)
BMC Evol Biol
, vol.14
, pp. 10
-
-
Cao, L.1
Chen, F.2
Yang, X.3
Xu, W.4
Xie, J.5
Yu, L.6
-
8
-
-
0033945894
-
Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa
-
Liu J, Kipreos ET: Evolution of cyclin-dependent kinases (CDKs) and CDK-activating kinases (CAKs): differential conservation of CAKs in yeast and metazoa. Mol Biol Evol 2000, 17:1061-1074.
-
(2000)
Mol Biol Evol
, vol.17
, pp. 1061-1074
-
-
Liu, J.1
Kipreos, E.T.2
-
9
-
-
34547952048
-
Cdk1 is sufficient to drive the mammalian cell cycle
-
Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, Caceres JF, Dubus P, Malumbres M, Barbacid M: Cdk1 is sufficient to drive the mammalian cell cycle. Nature 2007, 448:811-815.
-
(2007)
Nature
, vol.448
, pp. 811-815
-
-
Santamaria, D.1
Barriere, C.2
Cerqueira, A.3
Hunt, S.4
Tardy, C.5
Newton, K.6
Caceres, J.F.7
Dubus, P.8
Malumbres, M.9
Barbacid, M.10
-
10
-
-
0041854279
-
Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice
-
Ortega S, Prieto I, Odajima J, Martin A, Dubus P, Sotillo R, Barbero JL, Malumbres M, Barbacid M: Cyclin-dependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet 2003, 35:25-31.
-
(2003)
Nat Genet
, vol.35
, pp. 25-31
-
-
Ortega, S.1
Prieto, I.2
Odajima, J.3
Martin, A.4
Dubus, P.5
Sotillo, R.6
Barbero, J.L.7
Malumbres, M.8
Barbacid, M.9
-
11
-
-
34748832943
-
Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast
-
Huang D, Friesen H, Andrews B: Pho85, a multifunctional cyclin-dependent protein kinase in budding yeast. Mol Microbiol 2007, 66:303-314.
-
(2007)
Mol Microbiol
, vol.66
, pp. 303-314
-
-
Huang, D.1
Friesen, H.2
Andrews, B.3
-
12
-
-
71649108294
-
Cell cycle control of wnt receptor activation
-
Davidson G, Shen J, Huang YL, Su Y, Karaulanov E, Bartscherer K, Hassler C, Stannek P, Boutros M, Niehrs C: Cell cycle control of wnt receptor activation. Dev Cell 2009, 17:788-799.
-
(2009)
Dev Cell
, vol.17
, pp. 788-799
-
-
Davidson, G.1
Shen, J.2
Huang, Y.L.3
Su, Y.4
Karaulanov, E.5
Bartscherer, K.6
Hassler, C.7
Stannek, P.8
Boutros, M.9
Niehrs, C.10
-
13
-
-
84868011832
-
Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs
-
Mikolcevic P, Rainer J, Geley S: Orphan kinases turn eccentric: a new class of cyclin Y-activated, membrane-targeted CDKs. Cell Cycle 2012, 11:3758-3768.
-
(2012)
Cell Cycle
, vol.11
, pp. 3758-3768
-
-
Mikolcevic, P.1
Rainer, J.2
Geley, S.3
-
16
-
-
84859791205
-
Cyclin K goes with Cdk12 and Cdk13
-
Kohoutek J, Blazek D: Cyclin K goes with Cdk12 and Cdk13. Cell Div 2012, 7:12.
-
(2012)
Cell Div
, vol.7
, pp. 12
-
-
Kohoutek, J.1
Blazek, D.2
-
17
-
-
9144249813
-
Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs
-
Guo Z, Stiller JW: Comparative genomics of cyclin-dependent kinases suggest co-evolution of the RNAP II C-terminal domain and CTD-directed CDKs. BMC Genomics 2004, 5:69.
-
(2004)
BMC Genomics
, vol.5
, pp. 69
-
-
Guo, Z.1
Stiller, J.W.2
-
18
-
-
75349112388
-
Recent developments in cyclin-dependent kinase biochemical and structural studies
-
Echalier A, Endicott JA, Noble ME: Recent developments in cyclin-dependent kinase biochemical and structural studies. Biochim Biophys Acta 1804, 2010:511-519.
-
(1804)
Biochim Biophys Acta
, vol.2010
, pp. 511-519
-
-
Echalier, A.1
Endicott, J.A.2
Noble, M.E.3
-
19
-
-
0033574614
-
Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors
-
Pavletich NP: Mechanisms of cyclin-dependent kinase regulation: structures of Cdks, their cyclin activators, and Cip and INK4 inhibitors. J Mol Biol 1999, 287:821-828.
-
(1999)
J Mol Biol
, vol.287
, pp. 821-828
-
-
Pavletich, N.P.1
-
20
-
-
63149148791
-
Crystal structure of human CDK4 in complex with a D-type cyclin
-
Day PJ, Cleasby A, Tickle IJ, O'Reilly M, Coyle JE, Holding FP, McMenamin RL, Yon J, Chopra R, Lengauer C, Jhoti H: Crystal structure of human CDK4 in complex with a D-type cyclin. Proc Natl Acad Sci U S A 2009, 106:4166-4170.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4166-4170
-
-
Day, P.J.1
Cleasby, A.2
Tickle, I.J.3
O'Reilly, M.4
Coyle, J.E.5
Holding, F.P.6
McMenamin, R.L.7
Yon, J.8
Chopra, R.9
Lengauer, C.10
Jhoti, H.11
-
21
-
-
63149111417
-
The structure of CDK4/cyclin D3 has implications for models of CDK activation
-
Takaki T, Echalier A, Brown NR, Hunt T, Endicott JA, Noble ME: The structure of CDK4/cyclin D3 has implications for models of CDK activation. Proc Natl Acad Sci U S A 2009, 106:4171-4176.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 4171-4176
-
-
Takaki, T.1
Echalier, A.2
Brown, N.R.3
Hunt, T.4
Endicott, J.A.5
Noble, M.E.6
-
22
-
-
84856767106
-
Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis
-
Mikolcevic P, Sigl R, Rauch V, Hess MW, Pfaller K, Barisic M, Pelliniemi LJ, Boesl M, Geley S: Cyclin-dependent kinase 16/PCTAIRE kinase 1 is activated by cyclin Y and is essential for spermatogenesis. Mol Cell Biol 2012, 32:868-879.
-
(2012)
Mol Cell Biol
, vol.32
, pp. 868-879
-
-
Mikolcevic, P.1
Sigl, R.2
Rauch, V.3
Hess, M.W.4
Pfaller, K.5
Barisic, M.6
Pelliniemi, L.J.7
Boesl, M.8
Geley, S.9
-
23
-
-
34250865564
-
CDC25 phosphatases in cancer cells: key players? Good targets?
-
Boutros R, Lobjois V, Ducommun B: CDC25 phosphatases in cancer cells: key players? Good targets? Nat Rev Cancer 2007, 7:495-507.
-
(2007)
Nat Rev Cancer
, vol.7
, pp. 495-507
-
-
Boutros, R.1
Lobjois, V.2
Ducommun, B.3
-
24
-
-
0034671563
-
Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors
-
Jeffrey PD, Tong L, Pavletich NP: Structural basis of inhibition of CDK-cyclin complexes by INK4 inhibitors. Genes Dev 2000, 14:3115-3125.
-
(2000)
Genes Dev
, vol.14
, pp. 3115-3125
-
-
Jeffrey, P.D.1
Tong, L.2
Pavletich, N.P.3
-
25
-
-
0035754080
-
To cycle or not to cycle: a critical decision in cancer
-
Malumbres M, Barbacid M: To cycle or not to cycle: a critical decision in cancer. Nat Rev Cancer 2001, 1:222-231.
-
(2001)
Nat Rev Cancer
, vol.1
, pp. 222-231
-
-
Malumbres, M.1
Barbacid, M.2
-
26
-
-
84871513029
-
Deciphering the retinoblastoma protein phosphorylation code
-
Rubin SM: Deciphering the retinoblastoma protein phosphorylation code. Trends Biochem Sci 2013, 38:12-19.
-
(2013)
Trends Biochem Sci
, vol.38
, pp. 12-19
-
-
Rubin, S.M.1
-
27
-
-
4444247138
-
Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6
-
Malumbres M, Sotillo R, Santamaria D, Galan J, Cerezo A, Ortega S, Dubus P, Barbacid M: Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6. Cell 2004, 118:493-504.
-
(2004)
Cell
, vol.118
, pp. 493-504
-
-
Malumbres, M.1
Sotillo, R.2
Santamaria, D.3
Galan, J.4
Cerezo, A.5
Ortega, S.6
Dubus, P.7
Barbacid, M.8
-
28
-
-
84857781607
-
Cdk5: a multifaceted kinase in neurodegenerative diseases
-
Cheung ZH, Ip NY: Cdk5: a multifaceted kinase in neurodegenerative diseases. Trends Cell Biol 2012, 22:169-175.
-
(2012)
Trends Cell Biol
, vol.22
, pp. 169-175
-
-
Cheung, Z.H.1
Ip, N.Y.2
-
29
-
-
84866131320
-
Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5
-
Arif A: Extraneuronal activities and regulatory mechanisms of the atypical cyclin-dependent kinase Cdk5. Biochem Pharmacol 2012, 84:985-993.
-
(2012)
Biochem Pharmacol
, vol.84
, pp. 985-993
-
-
Arif, A.1
-
30
-
-
33744545575
-
Pctaire1 phosphorylates Nethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis
-
Liu Y, Cheng K, Gong K, Fu AK, Ip NY: Pctaire1 phosphorylates Nethylmaleimide-sensitive fusion protein: implications in the regulation of its hexamerization and exocytosis. J Biol Chem 2006, 281:9852-9858.
-
(2006)
J Biol Chem
, vol.281
, pp. 9852-9858
-
-
Liu, Y.1
Cheng, K.2
Gong, K.3
Fu, A.K.4
Ip, N.Y.5
-
31
-
-
77955317205
-
Emerging links between CDK cell cycle regulators and Wnt signaling
-
Davidson G, Niehrs C: Emerging links between CDK cell cycle regulators and Wnt signaling. Trends Cell Biol 2010, 20:453-460.
-
(2010)
Trends Cell Biol
, vol.20
, pp. 453-460
-
-
Davidson, G.1
Niehrs, C.2
-
32
-
-
84862493306
-
Updating the RNA polymerase CTD code: adding gene-specific layers
-
EgloffS, Dienstbier M, Murphy S: Updating the RNA polymerase CTD code: adding gene-specific layers. Trends Genet 2012, 28:333-341.
-
(2012)
Trends Genet
, vol.28
, pp. 333-341
-
-
Egloff, S.1
Dienstbier, M.2
Murphy, S.3
-
33
-
-
79960377780
-
A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor
-
Egly JM, Coin F: A history of TFIIH: two decades of molecular biology on a pivotal transcription/repair factor. DNA Repair (Amst) 2011, 10:714-721.
-
(2011)
DNA Repair (Amst)
, vol.10
, pp. 714-721
-
-
Egly, J.M.1
Coin, F.2
-
34
-
-
84869095110
-
Cyclin-dependent kinase control of the initiationto-elongation switch of RNA polymerase II
-
Larochelle S, Amat R, Glover-Cutter K, Sanso M, Zhang C, Allen JJ, Shokat KM, Bentley DL, Fisher RP: Cyclin-dependent kinase control of the initiationto-elongation switch of RNA polymerase II. Nat Struct Mol Biol 2012, 19:1108-1115.
-
(2012)
Nat Struct Mol Biol
, vol.19
, pp. 1108-1115
-
-
Larochelle, S.1
Amat, R.2
Glover-Cutter, K.3
Sanso, M.4
Zhang, C.5
Allen, J.J.6
Shokat, K.M.7
Bentley, D.L.8
Fisher, R.P.9
-
36
-
-
77958587420
-
CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1
-
Bartkowiak B, Liu P, Phatnani HP, Fuda NJ, Cooper JJ, Price DH, Adelman K, Lis JT, Greenleaf AL: CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1. Genes Dev 2010, 24:2303-2316.
-
(2010)
Genes Dev
, vol.24
, pp. 2303-2316
-
-
Bartkowiak, B.1
Liu, P.2
Phatnani, H.P.3
Fuda, N.J.4
Cooper, J.J.5
Price, D.H.6
Adelman, K.7
Lis, J.T.8
Greenleaf, A.L.9
-
37
-
-
80054756087
-
The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes
-
Blazek D, Kohoutek J, Bartholomeeusen K, Johansen E, Hulinkova P, Luo Z, Cimermancic P, Ule J, Peterlin BM: The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes. Genes Dev 2011, 25:2158-2172.
-
(2011)
Genes Dev
, vol.25
, pp. 2158-2172
-
-
Blazek, D.1
Kohoutek, J.2
Bartholomeeusen, K.3
Johansen, E.4
Hulinkova, P.5
Luo, Z.6
Cimermancic, P.7
Ule, J.8
Peterlin, B.M.9
-
38
-
-
84856133989
-
Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription
-
Clemente-Blanco A, Sen N, Mayan-Santos M, Sacristan MP, Graham B, Jarmuz A, Giess A, Webb E, Game L, Eick D, Bueno A, Merkenschlager M, Aragon L: Cdc14 phosphatase promotes segregation of telomeres through repression of RNA polymerase II transcription. Nat Cell Biol 2011, 13:1450-1456.
-
(2011)
Nat Cell Biol
, vol.13
, pp. 1450-1456
-
-
Clemente-Blanco, A.1
Sen, N.2
Mayan-Santos, M.3
Sacristan, M.P.4
Graham, B.5
Jarmuz, A.6
Giess, A.7
Webb, E.8
Game, L.9
Eick, D.10
Bueno, A.11
Merkenschlager, M.12
Aragon, L.13
-
39
-
-
84859772362
-
Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription
-
Guillamot M, Manchado E, ChiesaM, Gomez-Lopez G, Pisano DG, SacristanMP, Malumbres M: Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription. Sci Rep 2011, 1:189.
-
(2011)
Sci Rep
, vol.1
, pp. 189
-
-
Guillamot, M.1
Manchado, E.2
Chiesa, M.3
Gomez-Lopez, G.4
Pisano, D.G.5
Sacristan, M.P.6
Malumbres, M.7
-
41
-
-
2942575993
-
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology
-
Sato S, Tomomori-Sato C, Parmely TJ, Florens L, Zybailov B, Swanson SK, Banks CA, Jin J, Cai Y, Washburn MP, Conaway JW, Conaway RC: A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology. Mol Cell 2004, 14:685-691.
-
(2004)
Mol Cell
, vol.14
, pp. 685-691
-
-
Sato, S.1
Tomomori-Sato, C.2
Parmely, T.J.3
Florens, L.4
Zybailov, B.5
Swanson, S.K.6
Banks, C.A.7
Jin, J.8
Cai, Y.9
Washburn, M.P.10
Conaway, J.W.11
Conaway, R.C.12
-
42
-
-
0037424470
-
CDK11 complexes promote pre-mRNA splicing
-
Hu D, Mayeda A, Trembley JH, Lahti JM, Kidd VJ: CDK11 complexes promote pre-mRNA splicing. J Biol Chem 2003, 278:8623-8629.
-
(2003)
J Biol Chem
, vol.278
, pp. 8623-8629
-
-
Hu, D.1
Mayeda, A.2
Trembley, J.H.3
Lahti, J.M.4
Kidd, V.J.5
-
43
-
-
84870475491
-
Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complex
-
Drogat J, Migeot V, Mommaerts E, Mullier C, Dieu M, van Bakel H, Hermand D: Cdk11-cyclinL controls the assembly of the RNA polymerase II mediator complex. Cell Rep 2012, 2:1068-1076.
-
(2012)
Cell Rep
, vol.2
, pp. 1068-1076
-
-
Drogat, J.1
Migeot, V.2
Mommaerts, E.3
Mullier, C.4
Dieu, M.5
van Bakel, H.6
Hermand, D.7
-
44
-
-
80655124404
-
The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy
-
Wilkinson S, Croft DR, O'Prey J, Meedendorp A, O'Prey M, Dufes C, Ryan KM: The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy. Autophagy 2011, 7:1295-1301.
-
(2011)
Autophagy
, vol.7
, pp. 1295-1301
-
-
Wilkinson, S.1
Croft, D.R.2
O'Prey, J.3
Meedendorp, A.4
O'Prey, M.5
Dufes, C.6
Ryan, K.M.7
-
45
-
-
66549100281
-
Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitinproteasome degradation
-
Wang Y, Zong H, Chi Y, Hong Y, Yang Y, Zou W, Yun X, Gu J: Repression of estrogen receptor alpha by CDK11p58 through promoting its ubiquitinproteasome degradation. J Biochem 2009, 145:331-343.
-
(2009)
J Biochem
, vol.145
, pp. 331-343
-
-
Wang, Y.1
Zong, H.2
Chi, Y.3
Hong, Y.4
Yang, Y.5
Zou, W.6
Yun, X.7
Gu, J.8
-
46
-
-
67650079035
-
CDK11p58 represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation
-
Chi Y, Hong Y, Zong H, Wang Y, Zou W, Yang J, Kong X, Yun X, Gu J: CDK11p58 represses vitamin D receptor-mediated transcriptional activation through promoting its ubiquitin-proteasome degradation. Biochem Biophys Res Commun 2009, 386:493-498.
-
(2009)
Biochem Biophys Res Commun
, vol.386
, pp. 493-498
-
-
Chi, Y.1
Hong, Y.2
Zong, H.3
Wang, Y.4
Zou, W.5
Yang, J.6
Kong, X.7
Yun, X.8
Gu, J.9
-
47
-
-
33645525342
-
The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation
-
Petretti C, Savoian M, Montembault E, Glover DM, Prigent C, Giet R: The PITSLRE/CDK11p58 protein kinase promotes centrosome maturation and bipolar spindle formation. EMBO Rep 2006, 7:418-424.
-
(2006)
EMBO Rep
, vol.7
, pp. 418-424
-
-
Petretti, C.1
Savoian, M.2
Montembault, E.3
Glover, D.M.4
Prigent, C.5
Giet, R.6
-
48
-
-
34547767152
-
CDK11(p58) is required for the maintenance of sister chromatid cohesion
-
Hu D, Valentine M, Kidd VJ, Lahti JM: CDK11(p58) is required for the maintenance of sister chromatid cohesion. J Cell Sci 2007, 120:2424-2434.
-
(2007)
J Cell Sci
, vol.120
, pp. 2424-2434
-
-
Hu, D.1
Valentine, M.2
Kidd, V.J.3
Lahti, J.M.4
-
49
-
-
40849119789
-
Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate
-
Yokoyama H, Gruss OJ, Rybina S, Caudron M, Schelder M, Wilm M, Mattaj IW, Karsenti E: Cdk11 is a RanGTP-dependent microtubule stabilization factor that regulates spindle assembly rate. J Cell Biol 2008, 180:867-875.
-
(2008)
J Cell Biol
, vol.180
, pp. 867-875
-
-
Yokoyama, H.1
Gruss, O.J.2
Rybina, S.3
Caudron, M.4
Schelder, M.5
Wilm, M.6
Mattaj, I.W.7
Karsenti, E.8
-
50
-
-
84888363600
-
CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome
-
Guen VJ, Gamble C, Flajolet M, Unger S, Thollet A, Ferandin Y, Superti-Furga A, Cohen PA, Meijer L, Colas P: CDK10/cyclin M is a protein kinase that controls ETS2 degradation and is deficient in STAR syndrome. Proc Natl Acad Sci U S A 2013, 110:19525-19530.
-
(2013)
Proc Natl Acad Sci U S A
, vol.110
, pp. 19525-19530
-
-
Guen, V.J.1
Gamble, C.2
Flajolet, M.3
Unger, S.4
Thollet, A.5
Ferandin, Y.6
Superti-Furga, A.7
Cohen, P.A.8
Meijer, L.9
Colas, P.10
-
51
-
-
84899416693
-
In a non-genomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription
-
Liu W, Cai MJ, Wang JX, Zhao XF: In a non-genomic action, steroid hormone 20-hydroxyecdysone induces phosphorylation of cyclin-dependent kinase 10 to promote gene transcription. Endocrinology 2014, 155:1738-1750.
-
(2014)
Endocrinology
, vol.155
, pp. 1738-1750
-
-
Liu, W.1
Cai, M.J.2
Wang, J.X.3
Zhao, X.F.4
-
52
-
-
33644785933
-
The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity
-
Wohlbold L, Larochelle S, Liao JC, Livshits G, Singer J, Shokat KM, Fisher RP: The cyclin-dependent kinase (CDK) family member PNQALRE/CCRK supports cell proliferation but has no intrinsic CDK-activating kinase (CAK) activity. Cell Cycle 2006, 5:546-554.
-
(2006)
Cell Cycle
, vol.5
, pp. 546-554
-
-
Wohlbold, L.1
Larochelle, S.2
Liao, J.C.3
Livshits, G.4
Singer, J.5
Shokat, K.M.6
Fisher, R.P.7
-
53
-
-
33751017086
-
Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase
-
Fu Z, Larson KA, Chitta RK, Parker SA, Turk BE, Lawrence MW, Kaldis P, Galaktionov K, Cohn SM, Shabanowitz J, Hunt DF, Sturgill TW: Identification of yin-yang regulators and a phosphorylation consensus for male germ cell-associated kinase (MAK)-related kinase. Mol Cell Biol 2006, 26:8639-8654.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 8639-8654
-
-
Fu, Z.1
Larson, K.A.2
Chitta, R.K.3
Parker, S.A.4
Turk, B.E.5
Lawrence, M.W.6
Kaldis, P.7
Galaktionov, K.8
Cohn, S.M.9
Shabanowitz, J.10
Hunt, D.F.11
Sturgill, T.W.12
-
54
-
-
79961013561
-
Cell cycle-related kinase is a direct androgen receptor-regulated gene that drives beta-catenin/T cell factor-dependent hepatocarcinogenesis
-
Feng H, Cheng AS, Tsang DP, Li MS, Go MY, Cheung YS, Zhao GJ, Ng SS, Lin MC, Yu J, Lai PB, To KF, Sung JJ: Cell cycle-related kinase is a direct androgen receptor-regulated gene that drives beta-catenin/T cell factor-dependent hepatocarcinogenesis. J Clin Invest 2011, 121:3159-3175.
-
(2011)
J Clin Invest
, vol.121
, pp. 3159-3175
-
-
Feng, H.1
Cheng, A.S.2
Tsang, D.P.3
Li, M.S.4
Go, M.Y.5
Cheung, Y.S.6
Zhao, G.J.7
Ng, S.S.8
Lin, M.C.9
Yu, J.10
Lai, P.B.11
To, K.F.12
Sung, J.J.13
-
55
-
-
84881475435
-
CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner
-
Yang Y, Roine N, Makela TP: CCRK depletion inhibits glioblastoma cell proliferation in a cilium-dependent manner. EMBO Rep 2013, 14:741-747.
-
(2013)
EMBO Rep
, vol.14
, pp. 741-747
-
-
Yang, Y.1
Roine, N.2
Makela, T.P.3
-
56
-
-
23144451917
-
Cdc2-cyclin E complexes regulate the G1/S phase transition
-
Aleem E, Kiyokawa H, Kaldis P: Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol 2005, 7:831-836.
-
(2005)
Nat Cell Biol
, vol.7
, pp. 831-836
-
-
Aleem, E.1
Kiyokawa, H.2
Kaldis, P.3
-
57
-
-
84881528286
-
A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis
-
Kollmann K, Heller G, Schneckenleithner C, Warsch W, Scheicher R, Ott RG, Schafer M, Fajmann S, Schlederer M, Schiefer AI, Reichart U, Mayerhofer M, Hoeller C, Zochbauer-Muller S, Kerjaschki D, Bock C, Kenner L, Hoefler G, Freissmuth M, Green AR, Moriggl R, Busslinger M, Malumbres M, Sexl V: A kinase-independent function of CDK6 links the cell cycle to tumor angiogenesis. Cancer Cell 2013, 24:167-181.
-
(2013)
Cancer Cell
, vol.24
, pp. 167-181
-
-
Kollmann, K.1
Heller, G.2
Schneckenleithner, C.3
Warsch, W.4
Scheicher, R.5
Ott, R.G.6
Schafer, M.7
Fajmann, S.8
Schlederer, M.9
Schiefer, A.I.10
Reichart, U.11
Mayerhofer, M.12
Hoeller, C.13
Zochbauer-Muller, S.14
Kerjaschki, D.15
Bock, C.16
Kenner, L.17
Hoefler, G.18
Freissmuth, M.19
Green, A.R.20
Moriggl, R.21
Busslinger, M.22
Malumbres, M.23
Sexl, V.24
more..
-
58
-
-
84892840172
-
Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-kappaB-dependent gene expression
-
Handschick K, Beuerlein K, Jurida L, Bartkuhn M, Muller H, Soelch J, Weber A, Dittrich-Breiholz O, Schneider H, Scharfe M, Jarek M, Stellzig J, Schmitz ML, Kracht M: Cyclin-dependent kinase 6 is a chromatin-bound cofactor for NF-kappaB-dependent gene expression. Mol Cell 2014, 53:193-208.
-
(2014)
Mol Cell
, vol.53
, pp. 193-208
-
-
Handschick, K.1
Beuerlein, K.2
Jurida, L.3
Bartkuhn, M.4
Muller, H.5
Soelch, J.6
Weber, A.7
Dittrich-Breiholz, O.8
Schneider, H.9
Scharfe, M.10
Jarek, M.11
Stellzig, J.12
Schmitz, M.L.13
Kracht, M.14
-
59
-
-
84976226326
-
-
http://www.focr.org/breakthrough-therapies.
-
-
-
-
60
-
-
52949111487
-
CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity
-
Firestein R, Bass AJ, Kim SY, Dunn IF, Silver SJ, Guney I, Freed E, Ligon AH, Vena N, Ogino S, Chheda MG, Tamayo P, Finn S, Shrestha Y, Boehm JS, Jain S, Bojarski E, Mermel C, Barretina J, Chan JA, Baselga J, Tabernero J, Root DE, Fuchs CS, Loda M, Shivdasani RA, Meyerson M, Hahn WC: CDK8 is a colorectal cancer oncogene that regulates beta-catenin activity. Nature 2008, 455:547-551.
-
(2008)
Nature
, vol.455
, pp. 547-551
-
-
Firestein, R.1
Bass, A.J.2
Kim, S.Y.3
Dunn, I.F.4
Silver, S.J.5
Guney, I.6
Freed, E.7
Ligon, A.H.8
Vena, N.9
Ogino, S.10
Chheda, M.G.11
Tamayo, P.12
Finn, S.13
Shrestha, Y.14
Boehm, J.S.15
Jain, S.16
Bojarski, E.17
Mermel, C.18
Barretina, J.19
Chan, J.A.20
Baselga, J.21
Tabernero, J.22
Root, D.E.23
Fuchs, C.S.24
Loda, M.25
Shivdasani, R.A.26
Meyerson, M.27
Hahn, W.C.28
more..
-
61
-
-
52949093102
-
E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8
-
Morris EJ, Ji JY, Yang F, Di Stefano L, Herr A, Moon NS, Kwon EJ, Haigis KM, Naar AM, Dyson NJ: E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8. Nature 2008, 455:552-556.
-
(2008)
Nature
, vol.455
, pp. 552-556
-
-
Morris, E.J.1
Ji, J.Y.2
Yang, F.3
Di Stefano, L.4
Herr, A.5
Moon, N.S.6
Kwon, E.J.7
Haigis, K.M.8
Naar, A.M.9
Dyson, N.J.10
-
62
-
-
38549141939
-
Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer
-
Iorns E, Turner NC, Elliott R, Syed N, Garrone O, Gasco M, Tutt AN, Crook T, Lord CJ, Ashworth A: Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer. Cancer Cell 2008, 13:91-104.
-
(2008)
Cancer Cell
, vol.13
, pp. 91-104
-
-
Iorns, E.1
Turner, N.C.2
Elliott, R.3
Syed, N.4
Garrone, O.5
Gasco, M.6
Tutt, A.N.7
Crook, T.8
Lord, C.J.9
Ashworth, A.10
-
63
-
-
84892712017
-
Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity
-
Bajrami I, Frankum JR, Konde A, Miller RE, Rehman FL, Brough R, Campbell J, Sims D, Rafiq R, Hooper S, Chen L, Kozarewa I, Assiotis I, Fenwick K, Natrajan R, Lord CJ, Ashworth A: Genome-wide profiling of genetic synthetic lethality identifies CDK12 as a novel determinant of PARP1/2 inhibitor sensitivity. Cancer Res 2014, 74:287-297.
-
(2014)
Cancer Res
, vol.74
, pp. 287-297
-
-
Bajrami, I.1
Frankum, J.R.2
Konde, A.3
Miller, R.E.4
Rehman, F.L.5
Brough, R.6
Campbell, J.7
Sims, D.8
Rafiq, R.9
Hooper, S.10
Chen, L.11
Kozarewa, I.12
Assiotis, I.13
Fenwick, K.14
Natrajan, R.15
Lord, C.J.16
Ashworth, A.17
-
64
-
-
80455174794
-
A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility
-
Leung WK, Ching AK, Chan AW, Poon TC, Mian H, Wong AS, To KF, Wong N: A novel interplay between oncogenic PFTK1 protein kinase and tumor suppressor TAGLN2 in the control of liver cancer cell motility. Oncogene 2011, 30:4464-4475.
-
(2011)
Oncogene
, vol.30
, pp. 4464-4475
-
-
Leung, W.K.1
Ching, A.K.2
Chan, A.W.3
Poon, T.C.4
Mian, H.5
Wong, A.S.6
To, K.F.7
Wong, N.8
-
65
-
-
84866868120
-
Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma
-
Huang J, Deng Q, Wang Q, Li KY, Dai JH, Li N, Zhu ZD, Zhou B, Liu XY, Liu RF, Fei QL, Chen H, Cai B, Xiao HS, Qin LX, Han ZG: Exome sequencing of hepatitis B virus-associated hepatocellular carcinoma. Nat Genet 2012, 44:1117-1121.
-
(2012)
Nat Genet
, vol.44
, pp. 1117-1121
-
-
Huang, J.1
Deng, Q.2
Wang, Q.3
Li, K.Y.4
Dai, J.H.5
Li, N.6
Zhu, Z.D.7
Zhou, B.8
Liu, X.Y.9
Liu, R.F.10
Fei, Q.L.11
Chen, H.12
Cai, B.13
Xiao, H.S.14
Qin, L.X.15
Han, Z.G.16
-
66
-
-
84873177465
-
Phylogenetic analysis reveals the evolution and diversification of cyclins in eukaryotes
-
Ma Z, Wu Y, Jin J, Yan J, Kuang S, Zhou M, Zhang Y, Guo AY: Phylogenetic analysis reveals the evolution and diversification of cyclins in eukaryotes. Mol Phylogenet Evol 2013, 66:1002-1010.
-
(2013)
Mol Phylogenet Evol
, vol.66
, pp. 1002-1010
-
-
Ma, Z.1
Wu, Y.2
Jin, J.3
Yan, J.4
Kuang, S.5
Zhou, M.6
Zhang, Y.7
Guo, A.Y.8
-
67
-
-
0038157142
-
Xpd/Ercc2 regulates CAK activity and mitotic progression
-
Chen J, Larochelle S, Li X, Suter B: Xpd/Ercc2 regulates CAK activity and mitotic progression. Nature 2003, 424:228-232.
-
(2003)
Nature
, vol.424
, pp. 228-232
-
-
Chen, J.1
Larochelle, S.2
Li, X.3
Suter, B.4
|