SMN and symmetric arginine dimethylation of RNA polymerase II C-terminal domain control termination

Nature

Volumn 529, Issue 7584, 2016, Pages 48-53

  Yanling Zhao, Dorothy ^a,b   Gish, Gerald ^b   Braunschweig, Ulrich ^a   Li, Yue ^a,c   Ni, Zuyao ^a   Schmitges, Frank W ^a   Zhong, Guoqing ^a   Liu, Ke ^c   Li, Weiguo ^c   Moffat, Jason ^a   Vedadi, Masoud ^c   Min, Jinrong ^c   Pawson, Tony J ^a,b   Blencowe, Benjamin J ^a   Greenblatt, Jack F ^a  

^a UNIVERSITY OF TORONTO   (Canada)

^b MOUNT SINAI HOSPITAL   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; PROTEIN ARGININE METHYLTRANSFERASE; PROTEIN ARGININE METHYLTRANSFERASE 5; RNA POLYMERASE II; SMALL NUCLEAR RNA; SMALL NUCLEOLAR RNA; SURVIVAL MOTOR NEURON PROTEIN; UNCLASSIFIED DRUG; PRMT5 PROTEIN, HUMAN; PROTEIN BINDING; RNA HELICASE; SETX PROTEIN, HUMAN; SMN1 PROTEIN, HUMAN; SURVIVAL MOTOR NEURON PROTEIN 1;

DNA; EXPERIMENTAL STUDY; POLYMERASE CHAIN REACTION; RNA; SYMMETRY;

AMYOTROPHIC LATERAL SCLEROSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DNA DAMAGE; DNA RNA HYBRIDIZATION; ENZYME ACTIVE SITE; GENE EXPRESSION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; IN VIVO STUDY; MOTONEURON; PRIORITY JOURNAL; PROTEIN DOMAIN; RAJI CELL LINE; SPINAL MUSCULAR ATROPHY; STABLE EXPRESSION; TRANSCRIPTION TERMINATION; CELL LINE; CHEMISTRY; DEGENERATIVE DISEASE; GENETICS; METABOLISM; METHYLATION; PROTEIN TERTIARY STRUCTURE; TRANSCRIPTION ELONGATION;

VERTEBRATA;

ARGININE; CELL LINE; DNA DAMAGE; HUMANS; METHYLATION; NEURODEGENERATIVE DISEASES; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-ARGININE N-METHYLTRANSFERASES; RNA HELICASES; RNA POLYMERASE II; SURVIVAL OF MOTOR NEURON 1 PROTEIN; TRANSCRIPTION ELONGATION, GENETIC; TRANSCRIPTION TERMINATION, GENETIC;

EID: 84953897634     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16469     Document Type: Article

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