Development of 5‘ LTR DNA methylation of latent HIV-1 provirus in cell line models and in long-term-infected individuals

Clinical Epigenetics

Volumn 8, Issue 1, 2016, Pages 1-20

  Trejbalová, Kateřina ^a   Kovářová, Denisa ^a   Blažková, Jana ^a   Machala, Ladislav ^b   Jilich, David ^c   Weber, Jan ^d   Kučerová, Dana ^a   Vencálek, Ondřej ^e   Hirsch, Ivan ^{a,c,d,f,g,h,i}   Hejnar, Jiří ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b UNIVERSITY HOSPITAL BULOVKA   (Czech Republic)

^c CHARLES UNIVERSITY   (Czech Republic)

^d INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY   (Czech Republic)

^e PALACKÝ UNIVERSITY   (Czech Republic)

^f AIX MARSEILLE UNIVERSITY   (France)

^g INSTITUT PAOLI CALMETTES   (France)

^h AIX MARSEILLE UNIVERSITY   (France)

ⁱ CNRS   (France)

Author keywords

Chromatin conformation; DNA methylation; HIV 1; HIV 1 infected individuals; Latent HIV 1 provirus reactivation; Latent reservoir

Indexed keywords

ARTICLE; CD4+ T LYMPHOCYTE; CELL STIMULATION; CONTROLLED STUDY; CPG ISLAND; DNA METHYLATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; JURKAT CELL LINE; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROVIRUS; SEQUENCE ANALYSIS; VIRUS LATENCY; VIRUS REACTIVATION; CELL LINE; FEMALE; GENETICS; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HIV INFECTIONS; MALE; PHYSIOLOGY; TIME FACTOR; VIROLOGY;

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT;

ANTI-HIV AGENTS; ANTIRETROVIRAL THERAPY, HIGHLY ACTIVE; CELL LINE; DNA METHYLATION; FEMALE; HIV INFECTIONS; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; JURKAT CELLS; MALE; PROVIRUSES; TIME FACTORS; VIRUS LATENCY;

EID: 84958762691     PISSN: 18687075     EISSN: 18687083     Source Type: Journal    
DOI: 10.1186/s13148-016-0185-6     Document Type: Article

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