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Volumn 11, Issue 12, 2015, Pages

DNA Methylation: Insights into Human Evolution

Author keywords

[No Author keywords available]

Indexed keywords

DNA METHYLATION; EPIGENETICS; GENOME; HUMAN; HUMAN VERSUS ANIMAL COMPARISON; PRIMATE; ANIMAL; CPG ISLAND; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETICS; HUMAN GENOME; MOLECULAR EVOLUTION;

EID: 84953216625     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005661     Document Type: Review
Times cited : (85)

References (99)
  • 1
    • 84936991107 scopus 로고    scopus 로고
    • N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas
    • Fu Y, Luo GZ, Chen K, Deng X, Yu M, et al. N6-Methyldeoxyadenosine Marks Active Transcription Start Sites in Chlamydomonas. Cell. 2015;161: 879–892. doi: 10.1016/j.cell.2015.04.010 25936837
    • (2015) Cell , vol.161 , pp. 879-892
    • Fu, Y.1    Luo, G.Z.2    Chen, K.3    Deng, X.4    Yu, M.5
  • 2
    • 84936157640 scopus 로고    scopus 로고
    • N6-Methyladenine DNA Modification in Drosophila
    • Zhang G, Huang H, Liu D, Cheng Y, Liu X, et al. N6-Methyladenine DNA Modification in Drosophila. Cell. 2015;161: 893–906. doi: 10.1016/j.cell.2015.04.018 25936838
    • (2015) Cell , vol.161 , pp. 893-906
    • Zhang, G.1    Huang, H.2    Liu, D.3    Cheng, Y.4    Liu, X.5
  • 3
    • 84937012244 scopus 로고    scopus 로고
    • DNA Methylation on N6-Adenine in C. elegans
    • Greer EL, Blanco MA, Gu L, Sendinc E, Liu J, et al. DNA Methylation on N6-Adenine in C. elegans. Cell. 2015;161: 868–878. doi: 10.1016/j.cell.2015.04.005 25936839
    • (2015) Cell , vol.161 , pp. 868-878
    • Greer, E.L.1    Blanco, M.A.2    Gu, L.3    Sendinc, E.4    Liu, J.5
  • 4
    • 77952355762 scopus 로고    scopus 로고
    • Genome-wide evolutionary analysis of eukaryotic DNA methylation
    • Zemach A, McDaniel IE, Silva P, Zilberman D, Genome-wide evolutionary analysis of eukaryotic DNA methylation. Science. 2010;328: 916–919. doi: 10.1126/science.1186366 20395474
    • (2010) Science , vol.328 , pp. 916-919
    • Zemach, A.1    McDaniel, I.E.2    Silva, P.3    Zilberman, D.4
  • 5
    • 0035839057 scopus 로고    scopus 로고
    • The Role of DNA Methylation in Mammalian Epigenetics
    • Jones PA, The Role of DNA Methylation in Mammalian Epigenetics. Science. 2001;293: 1068–1070. 11498573
    • (2001) Science , vol.293 , pp. 1068-1070
    • Jones, P.A.1
  • 6
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A, CpG islands and the regulation of transcription. Genes Dev. 2011;25: 1010–1022. doi: 10.1101/gad.2037511 21576262
    • (2011) Genes Dev , vol.25 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 7
    • 84863986133 scopus 로고    scopus 로고
    • Functions of DNA methylation: islands, start sites, gene bodies and beyond
    • Jones PA, Functions of DNA methylation: islands, start sites, gene bodies and beyond. Nat Rev Genet. 2012;13: 484–492. doi: 10.1038/nrg3230 22641018
    • (2012) Nat Rev Genet , vol.13 , pp. 484-492
    • Jones, P.A.1
  • 8
    • 80053545055 scopus 로고    scopus 로고
    • DNA methylation profiles of human active and inactive X chromosomes
    • Sharp AJ, Stathaki E, Migliavacca E, Brahmachary M, Montgomery SB, et al. DNA methylation profiles of human active and inactive X chromosomes. Genome Res. 2011;21: 1592–1600. doi: 10.1101/gr.112680.110 21862626
    • (2011) Genome Res , vol.21 , pp. 1592-1600
    • Sharp, A.J.1    Stathaki, E.2    Migliavacca, E.3    Brahmachary, M.4    Montgomery, S.B.5
  • 9
    • 0027280881 scopus 로고
    • Methylation and imprinting: from host defense to gene regulation?
    • Barlow DP, Methylation and imprinting: from host defense to gene regulation? Science. 1993;260: 309–310. 8469984
    • (1993) Science , vol.260 , pp. 309-310
    • Barlow, D.P.1
  • 10
    • 84887214395 scopus 로고    scopus 로고
    • Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
    • Maunakea AK, Chepelev I, Cui K, Zhao K, Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition. Cell Res. 2013;23: 1256–1269. doi: 10.1038/cr.2013.110 23938295
    • (2013) Cell Res , vol.23 , pp. 1256-1269
    • Maunakea, A.K.1    Chepelev, I.2    Cui, K.3    Zhao, K.4
  • 11
    • 0031662164 scopus 로고    scopus 로고
    • Transcription of IAP endogenous retroviruses is constrained by cytosine methylation
    • Walsh CP, Chaillet JR, Bestor TH, Transcription of IAP endogenous retroviruses is constrained by cytosine methylation. Nat Genet. 1998;20: 116–117. 9771701
    • (1998) Nat Genet , vol.20 , pp. 116-117
    • Walsh, C.P.1    Chaillet, J.R.2    Bestor, T.H.3
  • 12
    • 70450217879 scopus 로고    scopus 로고
    • Human DNA methylomes at base resolution show widespread epigenomic differences
    • Lister R, Pelizzola M, Dowen RH, Hawkins RD, Hon G, et al. Human DNA methylomes at base resolution show widespread epigenomic differences. Nature. 2009;462: 315–322. doi: 10.1038/nature08514 19829295
    • (2009) Nature , vol.462 , pp. 315-322
    • Lister, R.1    Pelizzola, M.2    Dowen, R.H.3    Hawkins, R.D.4    Hon, G.5
  • 13
    • 84355163093 scopus 로고    scopus 로고
    • DNA-binding factors shape the mouse methylome at distal regulatory regions
    • Stadler MB, Murr R, Burger L, Ivanek R, Lienert F, et al. DNA-binding factors shape the mouse methylome at distal regulatory regions. Nature. 2011;480: 490–495. doi: 10.1038/nature10716 22170606
    • (2011) Nature , vol.480 , pp. 490-495
    • Stadler, M.B.1    Murr, R.2    Burger, L.3    Ivanek, R.4    Lienert, F.5
  • 14
    • 84865369147 scopus 로고    scopus 로고
    • DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells
    • Bock C, Beerman I, Lien WH, Smith ZD, Gu H, et al. DNA Methylation Dynamics during In Vivo Differentiation of Blood and Skin Stem Cells. Mol Cell. Elsevier; 2012;47: 633–647.
    • (2012) Mol Cell. Elsevier , vol.47 , pp. 633-647
    • Bock, C.1    Beerman, I.2    Lien, W.H.3    Smith, Z.D.4    Gu, H.5
  • 15
    • 84876836223 scopus 로고    scopus 로고
    • Modification of enhancer chromatin: what, how, and why?
    • Calo E, Wysocka J, Modification of enhancer chromatin: what, how, and why? Mol Cell. Elsevier Inc.; 2013;49: 825–837.
    • (2013) Mol Cell. Elsevier Inc. , vol.49 , pp. 825-837
    • Calo, E.1    Wysocka, J.2
  • 16
    • 84922621952 scopus 로고    scopus 로고
    • Function and information content of DNA methylation
    • Schübeler D, Function and information content of DNA methylation. Nature. 2015;517: 321–326. doi: 10.1038/nature14192 25592537
    • (2015) Nature , vol.517 , pp. 321-326
    • Schübeler, D.1
  • 17
    • 80054718602 scopus 로고    scopus 로고
    • Spontaneous epigenetic variation in the Arabidopsis thaliana methylome
    • Becker C, Hagmann J, Müller J, Koenig D, Stegle O, et al. Spontaneous epigenetic variation in the Arabidopsis thaliana methylome. Nature. 2011;480: 245–249. doi: 10.1038/nature10555 22057020
    • (2011) Nature , vol.480 , pp. 245-249
    • Becker, C.1    Hagmann, J.2    Müller, J.3    Koenig, D.4    Stegle, O.5
  • 18
    • 77950661675 scopus 로고    scopus 로고
    • Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes
    • Chen CL, Rappailles A, Duquenne L, Huvet M, Guilbaud G, et al. Impact of replication timing on non-CpG and CpG substitution rates in mammalian genomes. Genome Res. 2010;20: 447–457. doi: 10.1101/gr.098947.109 20103589
    • (2010) Genome Res , vol.20 , pp. 447-457
    • Chen, C.L.1    Rappailles, A.2    Duquenne, L.3    Huvet, M.4    Guilbaud, G.5
  • 19
    • 84879663784 scopus 로고    scopus 로고
    • Global epigenomic reconfiguration during mammalian brain development
    • Lister R, Mukamel EA, Nery JR, Urich M, Puddifoot CA, et al. Global epigenomic reconfiguration during mammalian brain development. Science. 2013;341: 1237905. doi: 10.1126/science.1237905 23828890
    • (2013) Science , vol.341 , pp. 1237905
    • Lister, R.1    Mukamel, E.A.2    Nery, J.R.3    Urich, M.4    Puddifoot, C.A.5
  • 20
    • 84938495948 scopus 로고    scopus 로고
    • Human body epigenome maps reveal noncanonical DNA methylation variation
    • Schultz MD, He Y, Whitaker JW, Hariharan M, Mukamel EA, et al. Human body epigenome maps reveal noncanonical DNA methylation variation. Nature. 2015;523: 212–216. doi: 10.1038/nature14465 26030523
    • (2015) Nature , vol.523 , pp. 212-216
    • Schultz, M.D.1    He, Y.2    Whitaker, J.W.3    Hariharan, M.4    Mukamel, E.A.5
  • 21
    • 84899091504 scopus 로고    scopus 로고
    • Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain
    • Wen L, Li X, Yan L, Tan Y, Li R, et al. Whole-genome analysis of 5-hydroxymethylcytosine and 5-methylcytosine at base resolution in the human brain. Genome Biol. 2014;15: R49. doi: 10.1186/gb-2014-15-3-r49 24594098
    • (2014) Genome Biol , vol.15 , pp. R49
    • Wen, L.1    Li, X.2    Yan, L.3    Tan, Y.4    Li, R.5
  • 22
    • 84870856116 scopus 로고    scopus 로고
    • Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum
    • Wang T, Pan Q, Lin L, Szulwach KE, Song CX, et al. Genome-wide DNA hydroxymethylation changes are associated with neurodevelopmental genes in the developing human cerebellum. Hum Mol Genet. 2012;21: 5500–5510. doi: 10.1093/hmg/dds394 23042784
    • (2012) Hum Mol Genet , vol.21 , pp. 5500-5510
    • Wang, T.1    Pan, Q.2    Lin, L.3    Szulwach, K.E.4    Song, C.X.5
  • 23
    • 84921057657 scopus 로고    scopus 로고
    • Advances in the profiling of DNA modifications: cytosine methylation and beyond
    • Plongthongkum N, Diep DH, Zhang K, Advances in the profiling of DNA modifications: cytosine methylation and beyond. Nat Rev Genet. 2014;15: 647–661. doi: 10.1038/nrg3772 25159599
    • (2014) Nat Rev Genet , vol.15 , pp. 647-661
    • Plongthongkum, N.1    Diep, D.H.2    Zhang, K.3
  • 24
    • 84937736036 scopus 로고    scopus 로고
    • 5-Formylcytosine can be a stable DNA modification in mammals
    • Bachman M, Uribe-Lewis S, Yang X, Burgess HE, Iurlaro M, et al. 5-Formylcytosine can be a stable DNA modification in mammals. Nat Chem Biol. 2015;11: 555–557. doi: 10.1038/nchembio.1848 26098680
    • (2015) Nat Chem Biol , vol.11 , pp. 555-557
    • Bachman, M.1    Uribe-Lewis, S.2    Yang, X.3    Burgess, H.E.4    Iurlaro, M.5
  • 25
    • 0016669094 scopus 로고
    • Evolution at two levels in humans and chimpanzees
    • King MC, Wilson AC, Evolution at two levels in humans and chimpanzees. Science. 1975;188: 107–116. 1090005
    • (1975) Science , vol.188 , pp. 107-116
    • King, M.C.1    Wilson, A.C.2
  • 27
    • 85027932742 scopus 로고    scopus 로고
    • Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides
    • Cooper DN, Mort M, Stenson PD, Ball EV, Chuzhanova NA, Methylation-mediated deamination of 5-methylcytosine appears to give rise to mutations causing human inherited disease in CpNpG trinucleotides, as well as in CpG dinucleotides. Hum Genomics. 2010;4: 406–410. 20846930
    • (2010) Hum Genomics , vol.4 , pp. 406-410
    • Cooper, D.N.1    Mort, M.2    Stenson, P.D.3    Ball, E.V.4    Chuzhanova, N.A.5
  • 28
    • 24344500211 scopus 로고    scopus 로고
    • Initial sequence of the chimpanzee genome and comparison with the human genome
    • Chimpanzee Sequencing and Analysis ConsortiumInitial sequence of the chimpanzee genome and comparison with the human genome. Nature. 2005;437: 69–87. 16136131
    • (2005) Nature , vol.437 , pp. 69-87
  • 29
    • 79957577720 scopus 로고    scopus 로고
    • Primate CpG islands are maintained by heterogeneous evolutionary regimes involving minimal selection
    • Cohen NM, Kenigsberg E, Tanay A, Primate CpG islands are maintained by heterogeneous evolutionary regimes involving minimal selection. Cell. 2011;145: 773–786. doi: 10.1016/j.cell.2011.04.024 21620139
    • (2011) Cell , vol.145 , pp. 773-786
    • Cohen, N.M.1    Kenigsberg, E.2    Tanay, A.3
  • 30
    • 0019322245 scopus 로고
    • DNA methylation and the frequency of CpG in animal DNA
    • Bird AP, DNA methylation and the frequency of CpG in animal DNA. Nucleic Acids Res. 1980;8: 1499–1504. 6253938
    • (1980) Nucleic Acids Res , vol.8 , pp. 1499-1504
    • Bird, A.P.1
  • 31
    • 84929480956 scopus 로고    scopus 로고
    • Synthetic CpG islands reveal DNA sequence determinants of chromatin structure
    • Wachter E, Quante T, Merusi C, Arczewska A, Stewart F, et al. Synthetic CpG islands reveal DNA sequence determinants of chromatin structure. Elife. 2014;3: e03397. doi: 10.7554/eLife.03397 25259796
    • (2014) Elife , vol.3 , pp. e03397
    • Wachter, E.1    Quante, T.2    Merusi, C.3    Arczewska, A.4    Stewart, F.5
  • 32
    • 84923119852 scopus 로고    scopus 로고
    • High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions
    • Krebs AR, Dessus-Babus S, Burger L, Schübeler D, High-throughput engineering of a mammalian genome reveals building principles of methylation states at CG rich regions. Elife. 2014;3: e04094. doi: 10.7554/eLife.04094 25259795
    • (2014) Elife , vol.3 , pp. e04094
    • Krebs, A.R.1    Dessus-Babus, S.2    Burger, L.3    Schübeler, D.4
  • 33
    • 67349190247 scopus 로고    scopus 로고
    • Linking DNA methylation and histone modification: patterns and paradigms
    • Cedar H, Bergman Y, Linking DNA methylation and histone modification: patterns and paradigms. Nat Rev Genet. 2009;10: 295–304. doi: 10.1038/nrg2540 19308066
    • (2009) Nat Rev Genet , vol.10 , pp. 295-304
    • Cedar, H.1    Bergman, Y.2
  • 34
    • 34547725157 scopus 로고    scopus 로고
    • DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA
    • Ooi SKT, Qiu C, Bernstein E, Li K, Jia D, et al. DNMT3L connects unmethylated lysine 4 of histone H3 to de novo methylation of DNA. Nature. 2007;448: 714–717. 17687327
    • (2007) Nature , vol.448 , pp. 714-717
    • Ooi, S.K.T.1    Qiu, C.2    Bernstein, E.3    Li, K.4    Jia, D.5
  • 35
    • 84878292464 scopus 로고    scopus 로고
    • ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection
    • Long HK, Blackledge NP, Klose RJ, ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection. Biochem Soc Trans. 2013;41: 727–740. doi: 10.1042/BST20130028 23697932
    • (2013) Biochem Soc Trans , vol.41 , pp. 727-740
    • Long, H.K.1    Blackledge, N.P.2    Klose, R.J.3
  • 36
    • 84895422951 scopus 로고    scopus 로고
    • Human-specific CpG “beacons” identify human-specific prefrontal cortex H3K4me3 chromatin peaks
    • Bell CG, Wilson GA, Beck S, Human-specific CpG “beacons” identify human-specific prefrontal cortex H3K4me3 chromatin peaks. Epigenomics. 2014;6: 21–31. doi: 10.2217/epi.13.74 24579944
    • (2014) Epigenomics , vol.6 , pp. 21-31
    • Bell, C.G.1    Wilson, G.A.2    Beck, S.3
  • 37
    • 33748675254 scopus 로고    scopus 로고
    • An RNA gene expressed during cortical development evolved rapidly in humans
    • Pollard KS, Salama SR, Lambert N, Lambot MA, Coppens S, et al. An RNA gene expressed during cortical development evolved rapidly in humans. Nature. 2006;443: 167–172. 16915236
    • (2006) Nature , vol.443 , pp. 167-172
    • Pollard, K.S.1    Salama, S.R.2    Lambert, N.3    Lambot, M.A.4    Coppens, S.5
  • 38
    • 80052918929 scopus 로고    scopus 로고
    • Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment
    • Hodges E, Molaro A, Dos Santos CO, Thekkat P, Song Q, et al. Directional DNA methylation changes and complex intermediate states accompany lineage specificity in the adult hematopoietic compartment. Mol Cell. 2011;44: 17–28. doi: 10.1016/j.molcel.2011.08.026 21924933
    • (2011) Mol Cell , vol.44 , pp. 17-28
    • Hodges, E.1    Molaro, A.2    Dos Santos, C.O.3    Thekkat, P.4    Song, Q.5
  • 39
    • 84882884517 scopus 로고    scopus 로고
    • Charting a dynamic DNA methylation landscape of the human genome
    • Ziller MJ, Gu H, Müller F, Donaghey J, Tsai LT, et al. Charting a dynamic DNA methylation landscape of the human genome. Nature. 2013;500: 477–481. doi: 10.1038/nature12433 23925113
    • (2013) Nature , vol.500 , pp. 477-481
    • Ziller, M.J.1    Gu, H.2    Müller, F.3    Donaghey, J.4    Tsai, L.T.5
  • 40
    • 84923366467 scopus 로고    scopus 로고
    • Transcription factor binding dynamics during human ES cell differentiation
    • Tsankov AM, Gu H, Akopian V, Ziller MJ, Donaghey J, et al. Transcription factor binding dynamics during human ES cell differentiation. Nature. 2015;518: 344–349. doi: 10.1038/nature14233 25693565
    • (2015) Nature , vol.518 , pp. 344-349
    • Tsankov, A.M.1    Gu, H.2    Akopian, V.3    Ziller, M.J.4    Donaghey, J.5
  • 41
    • 84926098534 scopus 로고    scopus 로고
    • Sequence-level mechanisms of human epigenome evolution
    • Prendergast JGD, Chambers EV, Semple CAM, Sequence-level mechanisms of human epigenome evolution. Genome Biol Evol. 2014;6: 1758–1771. doi: 10.1093/gbe/evu142 24966180
    • (2014) Genome Biol Evol , vol.6 , pp. 1758-1771
    • Prendergast, J.G.D.1    Chambers, E.V.2    Semple, C.A.M.3
  • 42
    • 77954238686 scopus 로고    scopus 로고
    • Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome
    • Shoemaker R, Deng J, Wang W, Zhang K, Allele-specific methylation is prevalent and is contributed by CpG-SNPs in the human genome. Genome Res. 2010;20: 883–889. doi: 10.1101/gr.104695.109 20418490
    • (2010) Genome Res , vol.20 , pp. 883-889
    • Shoemaker, R.1    Deng, J.2    Wang, W.3    Zhang, K.4
  • 43
    • 77649204292 scopus 로고    scopus 로고
    • Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain
    • Zhang D, Cheng L, Badner JA, Chen C, Chen Q, et al. Genetic Control of Individual Differences in Gene-Specific Methylation in Human Brain. Am J Hum Genet. 2010;86: 411–419. doi: 10.1016/j.ajhg.2010.02.005 20215007
    • (2010) Am J Hum Genet , vol.86 , pp. 411-419
    • Zhang, D.1    Cheng, L.2    Badner, J.A.3    Chen, C.4    Chen, Q.5
  • 44
    • 84883703352 scopus 로고    scopus 로고
    • DNA methylation contributes to natural human variation
    • Heyn H, Moran S, Hernando-Herraez I, Sayols S, Gomez A, et al. DNA methylation contributes to natural human variation. Genome Res. 2013;23: 1363–1372. doi: 10.1101/gr.154187.112 23908385
    • (2013) Genome Res , vol.23 , pp. 1363-1372
    • Heyn, H.1    Moran, S.2    Hernando-Herraez, I.3    Sayols, S.4    Gomez, A.5
  • 45
    • 84907584646 scopus 로고    scopus 로고
    • Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels
    • Banovich NE, Lan X, McVicker G, van de Geijn B, Degner JF, et al. Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels. PLoS Genet. 2014;10: e1004663. doi: 10.1371/journal.pgen.1004663 25233095
    • (2014) PLoS Genet , vol.10 , pp. e1004663
    • Banovich, N.E.1    Lan, X.2    McVicker, G.3    van de Geijn, B.4    Degner, J.F.5
  • 47
    • 84857474899 scopus 로고    scopus 로고
    • The evolution of mammalian genomic imprinting was accompanied by the acquisition of novel CpG islands
    • Suzuki S, Shaw G, Kaneko-Ishino T, Ishino F, Renfree MB, The evolution of mammalian genomic imprinting was accompanied by the acquisition of novel CpG islands. Genome Biol Evol. 2011;3: 1276–1283. doi: 10.1093/gbe/evr104 22016334
    • (2011) Genome Biol Evol , vol.3 , pp. 1276-1283
    • Suzuki, S.1    Shaw, G.2    Kaneko-Ishino, T.3    Ishino, F.4    Renfree, M.B.5
  • 48
    • 74249112469 scopus 로고    scopus 로고
    • The human retinoblastoma gene is imprinted
    • Kanber D, Berulava T, Ammerpohl O, Mitter D, Richter J, et al. The human retinoblastoma gene is imprinted. PLoS Genet. 2009;5: e1000790. doi: 10.1371/journal.pgen.1000790 20041224
    • (2009) PLoS Genet , vol.5 , pp. e1000790
    • Kanber, D.1    Berulava, T.2    Ammerpohl, O.3    Mitter, D.4    Richter, J.5
  • 49
    • 84861977900 scopus 로고    scopus 로고
    • Comparative epigenomic annotation of regulatory DNA
    • Xiao S, Xie D, Cao X, Yu P, Xing X, et al. Comparative epigenomic annotation of regulatory DNA. Cell. 2012;149: 1381–1392. doi: 10.1016/j.cell.2012.04.029 22682255
    • (2012) Cell , vol.149 , pp. 1381-1392
    • Xiao, S.1    Xie, D.2    Cao, X.3    Yu, P.4    Xing, X.5
  • 50
    • 84922295278 scopus 로고    scopus 로고
    • Enhancer Evolution across 20 Mammalian Species
    • Villar D, Berthelot C, Aldridge S, Rayner TF, Lukk M, et al. Enhancer Evolution across 20 Mammalian Species. Cell. 2015;160: 554–566. doi: 10.1016/j.cell.2015.01.006 25635462
    • (2015) Cell , vol.160 , pp. 554-566
    • Villar, D.1    Berthelot, C.2    Aldridge, S.3    Rayner, T.F.4    Lukk, M.5
  • 51
    • 84911470871 scopus 로고    scopus 로고
    • Conservation of trans-acting circuitry during mammalian regulatory evolution
    • Stergachis AB, Neph S, Sandstrom R, Haugen E, Reynolds AP, et al. Conservation of trans-acting circuitry during mammalian regulatory evolution. Nature. 2014;515: 365–370. doi: 10.1038/nature13972 25409825
    • (2014) Nature , vol.515 , pp. 365-370
    • Stergachis, A.B.1    Neph, S.2    Sandstrom, R.3    Haugen, E.4    Reynolds, A.P.5
  • 52
    • 84879049092 scopus 로고    scopus 로고
    • Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates
    • Long HK, Sims D, Heger A, Blackledge NP, Kutter C, et al. Epigenetic conservation at gene regulatory elements revealed by non-methylated DNA profiling in seven vertebrates. Elife. 2013;2: e00348. doi: 10.7554/eLife.00348 23467541
    • (2013) Elife , vol.2 , pp. e00348
    • Long, H.K.1    Sims, D.2    Heger, A.3    Blackledge, N.P.4    Kutter, C.5
  • 53
    • 79955403252 scopus 로고    scopus 로고
    • Gene expression differences among primates are associated with changes in a histone epigenetic modification
    • Cain CE, Blekhman R, Marioni JC, Gilad Y, Gene expression differences among primates are associated with changes in a histone epigenetic modification. Genetics. 2011;187: 1225–1234. doi: 10.1534/genetics.110.126177 21321133
    • (2011) Genetics , vol.187 , pp. 1225-1234
    • Cain, C.E.1    Blekhman, R.2    Marioni, J.C.3    Gilad, Y.4
  • 54
    • 84937492151 scopus 로고    scopus 로고
    • Epigenetic modifications are associated with inter-species gene expression variation in primates
    • Zhou X, Cain CE, Myrthil M, Lewellen N, Michelini K, et al. Epigenetic modifications are associated with inter-species gene expression variation in primates. Genome Biol. 2014;15: 547. 25468404
    • (2014) Genome Biol , vol.15 , pp. 547
    • Zhou, X.1    Cain, C.E.2    Myrthil, M.3    Lewellen, N.4    Michelini, K.5
  • 55
    • 84872815703 scopus 로고    scopus 로고
    • Latent regulatory potential of human-specific repetitive elements
    • Ward MC, Wilson MD, Barbosa-Morais NL, Schmidt D, Stark R, et al. Latent regulatory potential of human-specific repetitive elements. Mol Cell. 2013;49: 262–272. doi: 10.1016/j.molcel.2012.11.013 23246434
    • (2013) Mol Cell , vol.49 , pp. 262-272
    • Ward, M.C.1    Wilson, M.D.2    Barbosa-Morais, N.L.3    Schmidt, D.4    Stark, R.5
  • 56
    • 80052937538 scopus 로고    scopus 로고
    • Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates
    • Molaro A, Hodges E, Fang F, Song Q, McCombie WR, et al. Sperm methylation profiles reveal features of epigenetic inheritance and evolution in primates. Cell. 2011;146: 1029–1041. doi: 10.1016/j.cell.2011.08.016 21925323
    • (2011) Cell , vol.146 , pp. 1029-1041
    • Molaro, A.1    Hodges, E.2    Fang, F.3    Song, Q.4    McCombie, W.R.5
  • 57
    • 83055168369 scopus 로고    scopus 로고
    • Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states
    • Martin DIK, Singer M, Dhahbi J, Mao G, Zhang L, et al. Phyloepigenomic comparison of great apes reveals a correlation between somatic and germline methylation states. Genome Res. 2011;21: 2049–2057. doi: 10.1101/gr.122721.111 21908772
    • (2011) Genome Res , vol.21 , pp. 2049-2057
    • Martin, D.I.K.1    Singer, M.2    Dhahbi, J.3    Mao, G.4    Zhang, L.5
  • 58
    • 1542380557 scopus 로고    scopus 로고
    • Differences in DNA methylation patterns between humans and chimpanzees
    • Enard W, Fassbender A, Model F, Adorján P, Pääbo S, et al. Differences in DNA methylation patterns between humans and chimpanzees. Curr Biol. 2004;14: R148–9. 15027464
    • (2004) Curr Biol , vol.14 , pp. 9-148
    • Enard, W.1    Fassbender, A.2    Model, F.3    Adorján, P.4    Pääbo, S.5
  • 59
    • 66249089034 scopus 로고    scopus 로고
    • Differences in DNA methylation patterns and expression of the CCRK gene in human and nonhuman primate cortices
    • Farcas R, Schneider E, Frauenknecht K, Kondova I, Bontrop R, et al. Differences in DNA methylation patterns and expression of the CCRK gene in human and nonhuman primate cortices. Mol Biol Evol. 2009;26: 1379–1389. doi: 10.1093/molbev/msp046 19282513
    • (2009) Mol Biol Evol , vol.26 , pp. 1379-1389
    • Farcas, R.1    Schneider, E.2    Frauenknecht, K.3    Kondova, I.4    Bontrop, R.5
  • 60
    • 84880879361 scopus 로고    scopus 로고
    • Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes
    • Fukuda K, Ichiyanagi K, Yamada Y, Go Y, Udono T, et al. Regional DNA methylation differences between humans and chimpanzees are associated with genetic changes, transcriptional divergence and disease genes. J Hum Genet. 2013;58: 446–454. doi: 10.1038/jhg.2013.55 23739127
    • (2013) J Hum Genet , vol.58 , pp. 446-454
    • Fukuda, K.1    Ichiyanagi, K.2    Yamada, Y.3    Go, Y.4    Udono, T.5
  • 61
    • 84866081028 scopus 로고    scopus 로고
    • Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution
    • Zeng J, Konopka G, Hunt BG, Preuss TM, Geschwind D, et al. Divergent whole-genome methylation maps of human and chimpanzee brains reveal epigenetic basis of human regulatory evolution. Am J Hum Genet. 2012;91: 455–465. doi: 10.1016/j.ajhg.2012.07.024 22922032
    • (2012) Am J Hum Genet , vol.91 , pp. 455-465
    • Zeng, J.1    Konopka, G.2    Hunt, B.G.3    Preuss, T.M.4    Geschwind, D.5
  • 62
  • 63
    • 0242268390 scopus 로고    scopus 로고
    • Elevated gene expression levels distinguish human from non-human primate brains
    • Cáceres M, Lachuer J, Zapala MA, Redmond JC, Kudo L, et al. Elevated gene expression levels distinguish human from non-human primate brains. Proc Natl Acad Sci U S A. 2003;100: 13030–13035. 14557539
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13030-13035
    • Cáceres, M.1    Lachuer, J.2    Zapala, M.A.3    Redmond, J.C.4    Kudo, L.5
  • 64
    • 1542297747 scopus 로고    scopus 로고
    • Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles
    • Uddin M, Wildman DE, Liu G, Xu W, Johnson RM, et al. Sister grouping of chimpanzees and humans as revealed by genome-wide phylogenetic analysis of brain gene expression profiles. Proc Natl Acad Sci USA. 2004;101: 2957–2962. 14976249
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 2957-2962
    • Uddin, M.1    Wildman, D.E.2    Liu, G.3    Xu, W.4    Johnson, R.M.5
  • 65
    • 57149084867 scopus 로고    scopus 로고
    • Gene regulation in primates evolves under tissue-specific selection pressures
    • Blekhman R, Oshlack A, Chabot AE, Smyth GK, Gilad Y, Gene regulation in primates evolves under tissue-specific selection pressures. PLoS Genet. 2008;4: e1000271. doi: 10.1371/journal.pgen.1000271 19023414
    • (2008) PLoS Genet , vol.4 , pp. e1000271
    • Blekhman, R.1    Oshlack, A.2    Chabot, A.E.3    Smyth, G.K.4    Gilad, Y.5
  • 66
    • 22144447840 scopus 로고    scopus 로고
    • Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees
    • Khaitovich P, Hellmann I, Enard W, Nowick K, Leinweber M, et al. Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees. Science. 2005;309: 1850–1854. 16141373
    • (2005) Science , vol.309 , pp. 1850-1854
    • Khaitovich, P.1    Hellmann, I.2    Enard, W.3    Nowick, K.4    Leinweber, M.5
  • 67
    • 79952265169 scopus 로고    scopus 로고
    • A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues
    • Pai AA, Bell JT, Marioni JC, Pritchard JK, Gilad Y, A genome-wide study of DNA methylation patterns and gene expression levels in multiple human and chimpanzee tissues. PLoS Genet. 2011;7: e1001316. doi: 10.1371/journal.pgen.1001316 21383968
    • (2011) PLoS Genet , vol.7 , pp. e1001316
    • Pai, A.A.1    Bell, J.T.2    Marioni, J.C.3    Pritchard, J.K.4    Gilad, Y.5
  • 68
    • 84885021247 scopus 로고    scopus 로고
    • Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues
    • Hon GC, Rajagopal N, Shen Y, McCleary DF, Yue F, et al. Epigenetic memory at embryonic enhancers identified in DNA methylation maps from adult mouse tissues. Nat Genet. 2013;45: 1198–1206. doi: 10.1038/ng.2746 23995138
    • (2013) Nat Genet , vol.45 , pp. 1198-1206
    • Hon, G.C.1    Rajagopal, N.2    Shen, Y.3    McCleary, D.F.4    Yue, F.5
  • 69
    • 84879911829 scopus 로고    scopus 로고
    • The evolution of lineage-specific regulatory activities in the human embryonic limb
    • Cotney J, Leng J, Yin J, Reilly SK, DeMare LE, et al. The evolution of lineage-specific regulatory activities in the human embryonic limb. Cell. 2013;154: 185–196. doi: 10.1016/j.cell.2013.05.056 23827682
    • (2013) Cell , vol.154 , pp. 185-196
    • Cotney, J.1    Leng, J.2    Yin, J.3    Reilly, S.K.4    DeMare, L.E.5
  • 70
    • 84924561748 scopus 로고    scopus 로고
    • Evolutionary changes in promoter and enhancer activity during human corticogenesis
    • Reilly SK, Yin J, Ayoub AE, Emera D, Leng J, et al. Evolutionary changes in promoter and enhancer activity during human corticogenesis. Science. 2015;347: 1155–1159. doi: 10.1126/science.1260943 25745175
    • (2015) Science , vol.347 , pp. 1155-1159
    • Reilly, S.K.1    Yin, J.2    Ayoub, A.E.3    Emera, D.4    Leng, J.5
  • 71
    • 77952136530 scopus 로고    scopus 로고
    • A draft sequence of the Neandertal genome
    • Green RE, Krause J, Briggs AW, Maricic T, Stenzel U, et al. A draft sequence of the Neandertal genome. Science. 2010;328: 710–722. doi: 10.1126/science.1188021 20448178
    • (2010) Science , vol.328 , pp. 710-722
    • Green, R.E.1    Krause, J.2    Briggs, A.W.3    Maricic, T.4    Stenzel, U.5
  • 72
    • 84867331947 scopus 로고    scopus 로고
    • A high-coverage genome sequence from an archaic Denisovan individual
    • Meyer M, Kircher M, Gansauge MT, Li H, Racimo F, et al. A high-coverage genome sequence from an archaic Denisovan individual. Science. 2012;338: 222–226. doi: 10.1126/science.1224344 22936568
    • (2012) Science , vol.338 , pp. 222-226
    • Meyer, M.1    Kircher, M.2    Gansauge, M.T.3    Li, H.4    Racimo, F.5
  • 73
    • 84900442346 scopus 로고    scopus 로고
    • Reconstructing the DNA methylation maps of the Neandertal and the Denisovan
    • Gokhman D, Lavi E, Prüfer K, Fraga MF, Riancho JA, et al. Reconstructing the DNA methylation maps of the Neandertal and the Denisovan. Science. 2014;344: 523–527. doi: 10.1126/science.1250368 24786081
    • (2014) Science , vol.344 , pp. 523-527
    • Gokhman, D.1    Lavi, E.2    Prüfer, K.3    Fraga, M.F.4    Riancho, J.A.5
  • 74
    • 0037108033 scopus 로고    scopus 로고
    • Limb malformations and the human HOX genes
    • Goodman FR, Limb malformations and the human HOX genes. Am J Med Genet. 2002;112: 256–265. 12357469
    • (2002) Am J Med Genet , vol.112 , pp. 256-265
    • Goodman, F.R.1
  • 75
    • 84856791176 scopus 로고    scopus 로고
    • Population-specificity of human DNA methylation
    • Fraser HB, Lam LL, Neumann SM, Kobor MS, Population-specificity of human DNA methylation. Genome Biol. 2012;13: R8. doi: 10.1186/gb-2012-13-2-r8 22322129
    • (2012) Genome Biol , vol.13 , pp. R8
    • Fraser, H.B.1    Lam, L.L.2    Neumann, S.M.3    Kobor, M.S.4
  • 77
    • 84928533443 scopus 로고    scopus 로고
    • Genetic and environmental exposures constrain epigenetic drift over the human life course
    • Shah S, McRae AF, Marioni RE, Harris SE, Gibson J, et al. Genetic and environmental exposures constrain epigenetic drift over the human life course. Genome Res. 2014;24: 1725–1733. doi: 10.1101/gr.176933.114 25249537
    • (2014) Genome Res , vol.24 , pp. 1725-1733
    • Shah, S.1    McRae, A.F.2    Marioni, R.E.3    Harris, S.E.4    Gibson, J.5
  • 78
    • 59249107052 scopus 로고    scopus 로고
    • DNA methylation profiles in monozygotic and dizygotic twins
    • Kaminsky ZA, Tang T, Wang SC, Ptak C, Oh GHT, et al. DNA methylation profiles in monozygotic and dizygotic twins. Nat Genet. 2009;41: 240–245. doi: 10.1038/ng.286 19151718
    • (2009) Nat Genet , vol.41 , pp. 240-245
    • Kaminsky, Z.A.1    Tang, T.2    Wang, S.C.3    Ptak, C.4    Oh, G.H.T.5
  • 79
    • 84897139220 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance: myths and mechanisms
    • Heard E, Martienssen RA, Transgenerational epigenetic inheritance: myths and mechanisms. Cell. 2014;157: 95–109. doi: 10.1016/j.cell.2014.02.045 24679529
    • (2014) Cell , vol.157 , pp. 95-109
    • Heard, E.1    Martienssen, R.A.2
  • 80
    • 84875235105 scopus 로고    scopus 로고
    • Bridging the transgenerational gap with epigenetic memory
    • Lim JP, Brunet A, Bridging the transgenerational gap with epigenetic memory. Trends Genet. 2013;29: 176–186. doi: 10.1016/j.tig.2012.12.008 23410786
    • (2013) Trends Genet , vol.29 , pp. 176-186
    • Lim, J.P.1    Brunet, A.2
  • 81
    • 78049414227 scopus 로고    scopus 로고
    • Epigenetic reprogramming in plant and animal development
    • Feng S, Jacobsen SE, Reik W, Epigenetic reprogramming in plant and animal development. Science. 2010;330: 622–627. doi: 10.1126/science.1190614 21030646
    • (2010) Science , vol.330 , pp. 622-627
    • Feng, S.1    Jacobsen, S.E.2    Reik, W.3
  • 82
    • 84858071017 scopus 로고    scopus 로고
    • Epigenetic and epigenomic variation in Arabidopsis thaliana
    • Schmitz RJ, Ecker JR, Epigenetic and epigenomic variation in Arabidopsis thaliana. Trends Plant Sci. 2012;17: 149–154. doi: 10.1016/j.tplants.2012.01.001 22342533
    • (2012) Trends Plant Sci , vol.17 , pp. 149-154
    • Schmitz, R.J.1    Ecker, J.R.2
  • 83
    • 84867390947 scopus 로고    scopus 로고
    • Epialleles in plant evolution
    • Weigel D, Colot V, Epialleles in plant evolution. Genome Biol. 2012;13: 249. doi: 10.1186/gb-2012-13-10-249 23058244
    • (2012) Genome Biol , vol.13 , pp. 249
    • Weigel, D.1    Colot, V.2
  • 84
    • 79961209906 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance in plants
    • Hauser MT, Aufsatz W, Jonak C, Luschnig C, Transgenerational epigenetic inheritance in plants. Biochim Biophys Acta. 2011;1809: 459–468. doi: 10.1016/j.bbagrm.2011.03.007 21515434
    • (2011) Biochim Biophys Acta , vol.1809 , pp. 459-468
    • Hauser, M.T.1    Aufsatz, W.2    Jonak, C.3    Luschnig, C.4
  • 85
    • 84859002909 scopus 로고    scopus 로고
    • Parallel mechanisms of epigenetic reprogramming in the germline
    • Hackett JA, Zylicz JJ, Surani MA, Parallel mechanisms of epigenetic reprogramming in the germline. Trends Genet. 2012;28: 164–174. doi: 10.1016/j.tig.2012.01.005 22386917
    • (2012) Trends Genet , vol.28 , pp. 164-174
    • Hackett, J.A.1    Zylicz, J.J.2    Surani, M.A.3
  • 86
    • 84871702441 scopus 로고    scopus 로고
    • The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells
    • Seisenberger S, Andrews S, Krueger F, Arand J, Walter J, et al. The dynamics of genome-wide DNA methylation reprogramming in mouse primordial germ cells. Mol Cell. 2012;48: 849–862. doi: 10.1016/j.molcel.2012.11.001 23219530
    • (2012) Mol Cell , vol.48 , pp. 849-862
    • Seisenberger, S.1    Andrews, S.2    Krueger, F.3    Arand, J.4    Walter, J.5
  • 87
    • 84930618214 scopus 로고    scopus 로고
    • A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development
    • Tang WWC, Dietmann S, Irie N, Leitch HG, Floros VI, et al. A Unique Gene Regulatory Network Resets the Human Germline Epigenome for Development. Cell. 2015;161: 1453–1467. doi: 10.1016/j.cell.2015.04.053 26046444
    • (2015) Cell , vol.161 , pp. 1453-1467
    • Tang, W.W.C.1    Dietmann, S.2    Irie, N.3    Leitch, H.G.4    Floros, V.I.5
  • 88
    • 0032751471 scopus 로고    scopus 로고
    • Epigenetic inheritance at the agouti locus in the mouse
    • Morgan HD, Sutherland HG, Martin DI, Whitelaw E, Epigenetic inheritance at the agouti locus in the mouse. Nat Genet. 1999;23: 314–318. 10545949
    • (1999) Nat Genet , vol.23 , pp. 314-318
    • Morgan, H.D.1    Sutherland, H.G.2    Martin, D.I.3    Whitelaw, E.4
  • 89
    • 0037418193 scopus 로고    scopus 로고
    • Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission
    • Rakyan VK, Chong S, Champ ME, Cuthbert PC, Morgan HD, et al. Transgenerational inheritance of epigenetic states at the murine Axin(Fu) allele occurs after maternal and paternal transmission. Proc Natl Acad Sci USA. 2003;100: 2538–2543. 12601169
    • (2003) Proc Natl Acad Sci USA , vol.100 , pp. 2538-2543
    • Rakyan, V.K.1    Chong, S.2    Champ, M.E.3    Cuthbert, P.C.4    Morgan, H.D.5
  • 90
    • 78650446334 scopus 로고    scopus 로고
    • Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals
    • Carone BR, Fauquier L, Habib N, Shea JM, Hart CE, et al. Paternally induced transgenerational environmental reprogramming of metabolic gene expression in mammals. Cell. 2010;143: 1084–1096. doi: 10.1016/j.cell.2010.12.008 21183072
    • (2010) Cell , vol.143 , pp. 1084-1096
    • Carone, B.R.1    Fauquier, L.2    Habib, N.3    Shea, J.M.4    Hart, C.E.5
  • 91
    • 84893691607 scopus 로고    scopus 로고
    • Parental olfactory experience influences behavior and neural structure in subsequent generations
    • Dias BG, Ressler KJ, Parental olfactory experience influences behavior and neural structure in subsequent generations. Nat Neurosci. 2014;17: 89–96. doi: 10.1038/nn.3594 24292232
    • (2014) Nat Neurosci , vol.17 , pp. 89-96
    • Dias, B.G.1    Ressler, K.J.2
  • 92
    • 68049107038 scopus 로고    scopus 로고
    • Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the study of heredity and evolution
    • Jablonka E, Raz G, Transgenerational epigenetic inheritance: prevalence, mechanisms, and implications for the study of heredity and evolution. Q Rev Biol. 2009;84: 131–176. 19606595
    • (2009) Q Rev Biol , vol.84 , pp. 131-176
    • Jablonka, E.1    Raz, G.2
  • 93
    • 33646193822 scopus 로고    scopus 로고
    • Inherited epigenetic variation—revisiting soft inheritance
    • Richards EJ, Inherited epigenetic variation—revisiting soft inheritance. Nat Rev Genet. 2006;7: 395–401. 16534512
    • (2006) Nat Rev Genet , vol.7 , pp. 395-401
    • Richards, E.J.1
  • 94
    • 84865790047 scopus 로고    scopus 로고
    • An integrated encyclopedia of DNA elements in the human genome
    • Bernstein BE, Birney E, Dunham I, Green ED, Gunter C, et al. An integrated encyclopedia of DNA elements in the human genome. Nature. 2012;489: 57–74. doi: 10.1038/nature11247 22955616
    • (2012) Nature , vol.489 , pp. 57-74
    • Bernstein, B.E.1    Birney, E.2    Dunham, I.3    Green, E.D.4    Gunter, C.5
  • 95
    • 84923362619 scopus 로고    scopus 로고
    • Integrative analysis of 111 reference human epigenomes
    • Consortium RE, Kundaje A, Meuleman W, Ernst J, Bilenky M, et al. Integrative analysis of 111 reference human epigenomes. Nature. 2015;518: 317–330. doi: 10.1038/nature14248 25693563
    • (2015) Nature , vol.518 , pp. 317-330
    • Consortium, R.E.1    Kundaje, A.2    Meuleman, W.3    Ernst, J.4    Bilenky, M.5
  • 96
    • 84905405443 scopus 로고    scopus 로고
    • Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity
    • Smallwood SA, Lee HJ, Angermueller C, Krueger F, Saadeh H, et al. Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity. Nat Methods. 2014;11: 817–820. doi: 10.1038/nmeth.3035 25042786
    • (2014) Nat Methods , vol.11 , pp. 817-820
    • Smallwood, S.A.1    Lee, H.J.2    Angermueller, C.3    Krueger, F.4    Saadeh, H.5
  • 97
    • 65849256049 scopus 로고    scopus 로고
    • A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice
    • Enard W, Gehre S, Hammerschmidt K, Hölter SM, Blass T, et al. A Humanized Version of Foxp2 Affects Cortico-Basal Ganglia Circuits in Mice. Cell. 2009;137: 961–971. doi: 10.1016/j.cell.2009.03.041 19490899
    • (2009) Cell , vol.137 , pp. 961-971
    • Enard, W.1    Gehre, S.2    Hammerschmidt, K.3    Hölter, S.M.4    Blass, T.5
  • 99
    • 85042249404 scopus 로고    scopus 로고
    • A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics
    • Gallego-Romero I, Pavlovic BJ, Hernando-Herraez I, Zhou X, Ward MC, et al. A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Elife. 2015;4: 1–29.
    • (2015) Elife , vol.4 , pp. 1-29
    • Gallego-Romero, I.1    Pavlovic, B.J.2    Hernando-Herraez, I.3    Zhou, X.4    Ward, M.C.5


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