메뉴 건너뛰기




Volumn 6, Issue 1, 2000, Pages 82-85

The decay of the latent reservoir of replication-competent HIV-1 is inversely correlated with the extent of residual viral replication during prolonged anti-retroviral therapy

Author keywords

[No Author keywords available]

Indexed keywords

ABACAVIR; AMPRENAVIR; ANTIRETROVIRUS AGENT; DIDANOSINE; INDINAVIR; LAMIVUDINE; RITONAVIR; SAQUINAVIR; STAVUDINE; ZIDOVUDINE;

EID: 0033984045     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/71577     Document Type: Article
Times cited : (426)

References (25)
  • 1
    • 14444273439 scopus 로고    scopus 로고
    • Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy
    • Finzi, D. et al. Identification of a reservoir for HIV-1 in patients on highly active antiretroviral therapy. Science 278, 1295-1 300 (1997).
    • (1997) Science , vol.278 , pp. 1295-1300
    • Finzi, D.1
  • 2
    • 0030712305 scopus 로고    scopus 로고
    • Recovery of replication-competent HIV despite prolonged suppression of plasma viremia
    • Wong, J.K. et al. Recovery of replication-competent HIV despite prolonged suppression of plasma viremia. Science 278, 1291-1295 (1997).
    • (1997) Science , vol.278 , pp. 1291-1295
    • Wong, J.K.1
  • 3
    • 0030659177 scopus 로고    scopus 로고
    • Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy
    • Chun, T-W. et al. Presence of an inducible HIV-1 latent reservoir during highly active antiretroviral therapy. Proc. Natl. Acad. Sci. USA 94, 13193-13197 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 13193-13197
    • Chun, T.-W.1
  • 4
    • 0028792184 scopus 로고
    • In vivo fate of HIV-1 infected cells: Quantitative analysis of the transition to stable latency
    • Chun, T-W. et al. In vivo fate of HIV-1 infected cells: quantitative analysis of the transition to stable latency. Nature Med. 1, 1284-1290 (1995).
    • (1995) Nature Med. , vol.1 , pp. 1284-1290
    • Chun, T.-W.1
  • 5
    • 0030913366 scopus 로고    scopus 로고
    • Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection
    • Chun, T-W. et al Quantification of latent tissue reservoirs and total body viral load in HIV-1 infection. Nature 387, 183-188 (1997).
    • (1997) Nature , vol.387 , pp. 183-188
    • Chun, T.-W.1
  • 6
    • 0032546919 scopus 로고    scopus 로고
    • Toward HIV eradication or remission: The tasks ahead
    • Ho, D.D. Toward HIV eradication or remission: the tasks ahead. Science 280, 1866-1867 (1998).
    • (1998) Science , vol.280 , pp. 1866-1867
    • Ho, D.D.1
  • 7
    • 0033609373 scopus 로고    scopus 로고
    • Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy
    • Zhang, L. et al. Quantifying residual HIV-1 replication in patients receiving combination antiretroviral therapy. N. Engl. J. Med. 340, 1605-1613 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1605-1613
    • Zhang, L.1
  • 8
    • 0026445567 scopus 로고
    • Lifespan of human lymphocyte subsets defined by CD45 isoforms
    • Michie, C.A., McLean, A., Alcock, B. & Beverley, P.C. Lifespan of human lymphocyte subsets defined by CD45 isoforms. Nature 360, 264-265 (1992).
    • (1992) Nature , vol.360 , pp. 264-265
    • Michie, C.A.1    McLean, A.2    Alcock, B.3    Beverley, P.C.4
  • 9
    • 17444379333 scopus 로고    scopus 로고
    • Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans
    • Hellerstein, M et al. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1-infected humans. Nature Med. 5. 83-89 (1999).
    • (1999) Nature Med. , vol.5 , pp. 83-89
    • Hellerstein, M.1
  • 10
    • 0032549086 scopus 로고    scopus 로고
    • Rapid turnover of T lymphocytes in SIV-infected rhesus macaques
    • Mohri, H., Bonhoeffer, S., Monard, S., Perelson, A.S., Ho, D.D. Rapid turnover of T lymphocytes in SIV-infected rhesus macaques. Science 279, 1223-1227 (1998).
    • (1998) Science , vol.279 , pp. 1223-1227
    • Mohri, H.1    Bonhoeffer, S.2    Monard, S.3    Perelson, A.S.4    Ho, D.D.5
  • 11
    • 0032953920 scopus 로고    scopus 로고
    • Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy
    • Finzi, D. et al. Latent infection of CD4+ T cells provides a mechanism for lifelong persistence of HIV-1, even in patients on effective combination therapy. Nature Med. 5, 512-517 (1999).
    • (1999) Nature Med. , vol.5 , pp. 512-517
    • Finzi, D.1
  • 12
    • 0032899688 scopus 로고    scopus 로고
    • Design and analysis of serial limiting dilution assays with small sample sizes
    • Macken, C.A. Design and analysis of serial limiting dilution assays with small sample sizes. J. Immunol. Meth. 222, 13-29 (1999).
    • (1999) J. Immunol. Meth. , vol.222 , pp. 13-29
    • Macken, C.A.1
  • 13
    • 0029967721 scopus 로고    scopus 로고
    • HIV-1 dynamics in vivo: Virion clearance rate, infected cell life-span and viral generation time
    • Perelson, A.S., Neumann, A.D., Markowitz, M., Leonard, J.M., Ho, D.D. HIV-1 dynamics in vivo: virion clearance rate, infected cell life-span and viral generation time. Science 271, 1582-1586 (1996).
    • (1996) Science , vol.271 , pp. 1582-1586
    • Perelson, A.S.1    Neumann, A.D.2    Markowitz, M.3    Leonard, J.M.4    Ho, D.D.5
  • 14
    • 0028811974 scopus 로고
    • Viral dynamics in human immunodeficiency virus type 1 infection
    • Wei, X. et al. Viral dynamics in human immunodeficiency virus type 1 infection. Nature 373, 117-122 (1995).
    • (1995) Nature , vol.373 , pp. 117-122
    • Wei, X.1
  • 15
    • 0028874048 scopus 로고
    • Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
    • Ho, D.D. et al. Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection. Nature 373, 123-126 (1995).
    • (1995) Nature , vol.373 , pp. 123-126
    • Ho, D.D.1
  • 16
    • 0030952479 scopus 로고    scopus 로고
    • Decay characteristics of HIV-1 infected compartments during combination therapy
    • Perelson, A.S. et al. Decay characteristics of HIV-1 infected compartments during combination therapy. Nature 387, 188-191 (1997).
    • (1997) Nature , vol.387 , pp. 188-191
    • Perelson, A.S.1
  • 17
    • 0033609374 scopus 로고    scopus 로고
    • Persistence of HIV-1 transcription in peripheral blood mononuclear cells in patients receiving potent antiretroviral therapy
    • Furtado, M.R. et al. Persistence of HIV-1 transcription in peripheral blood mononuclear cells in patients receiving potent antiretroviral therapy. N. Engl. J. Med. 340, 1614-1622 (1999).
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1614-1622
    • Furtado, M.R.1
  • 18
    • 0033537355 scopus 로고    scopus 로고
    • HIV-1 replication in patients with undetectable plasma virus receiving HAART
    • Natarajan, V. et al. HIV-1 replication in patients with undetectable plasma virus receiving HAART. Lancet 353, 119-120 (1999).
    • (1999) Lancet , vol.353 , pp. 119-120
    • Natarajan, V.1
  • 19
    • 0033031005 scopus 로고    scopus 로고
    • The use of real-time PCR and molecular beacons to detect virus replication in HIV-1 infected individuals on prolonged effective antiretroviral therapy
    • Lewin, S.R. et al. The use of real-time PCR and molecular beacons to detect virus replication in HIV-1 infected individuals on prolonged effective antiretroviral therapy. J. Virol. 73, 6099-6103 (1999).
    • (1999) J. Virol. , vol.73 , pp. 6099-6103
    • Lewin, S.R.1
  • 20
    • 0345363096 scopus 로고    scopus 로고
    • Higher selection pressure from antiretroviral drugs in vivo results in increased evolutionary distance in HIV-1 pol
    • Gunthard, H.F. et al Higher selection pressure from antiretroviral drugs in vivo results in increased evolutionary distance in HIV-1 pol. Virology 259, 154-165 (1999).
    • (1999) Virology , vol.259 , pp. 154-165
    • Gunthard, H.F.1
  • 21
    • 0032531174 scopus 로고    scopus 로고
    • The era of adherence to HIV therapy
    • Altice, F.L. & Friedland, G.H. The era of adherence to HIV therapy. Ann. Intern. Med. 129, 503-505 (1998).
    • (1998) Ann. Intern. Med. , vol.129 , pp. 503-505
    • Altice, F.L.1    Friedland, G.H.2
  • 22
    • 0033587510 scopus 로고    scopus 로고
    • Highly active antiretroviral therapy in a large urban clinic: Risk factors for virologic failure and adverse drug reactions
    • Lucas, G.M., Chaisson, R.E. & Moore, R.D. Highly active antiretroviral therapy in a large urban clinic: risk factors for virologic failure and adverse drug reactions. Ann. Intern. Med. 131, 81-87 (1999).
    • (1999) Ann. Intern. Med. , vol.131 , pp. 81-87
    • Lucas, G.M.1    Chaisson, R.E.2    Moore, R.D.3
  • 23
    • 2642709177 scopus 로고    scopus 로고
    • Declining morbidity and mortality among patients with advanced human immunodeficiency
    • Palella, F.J. et al. Declining morbidity and mortality among patients with advanced human immunodeficiency. N. Engl. J. Med. 338, 853-860 (1998).
    • (1998) N. Engl. J. Med. , vol.338 , pp. 853-860
    • Palella, F.J.1
  • 24
    • 0032719664 scopus 로고    scopus 로고
    • HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of HAART
    • Ortiz, G.M. et al. HIV-1-specific immune responses in subjects who temporarily contain virus replication after discontinuation of HAART. J. Clin. Invest. 104,-R13-R18 (1999).
    • (1999) J. Clin. Invest. , vol.104
    • Ortiz, G.M.1
  • 25
    • 0033031218 scopus 로고    scopus 로고
    • + T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy
    • + T cells in HIV-1-infected patients receiving highly active anti-retroviral therapy. Nature Med. 5, 651-655 (1999).
    • (1999) Nature Med. , vol.5 , pp. 651-655
    • Chun, T.-W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.