Specific HIV integration sites are linked to clonal expansion and persistence of infected cells

Science

Volumn 345, Issue 6193, 2014, Pages 179-183

  Maldarelli, F ^a   Wu, X ^b   Su, L ^b   Simonetti, F R ^a,c   Shao, W ^b   Hill, S ^a   Spindler, J ^a   Ferris, A L ^a   Mellors, J W ^d   Kearney, M F ^a   Coffin, J M ^e   Hughes, S H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b FREDERICK NATIONAL LABORATORY FOR CANCER RESEARCH   (United States)

^c UNIVERSITY OF MILAN   (Italy)

^d UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^e TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; SPACER DNA; VIRUS RNA; ANTIRETROVIRUS AGENT; BACH2 PROTEIN, HUMAN; BASIC LEUCINE ZIPPER TRANSCRIPTION FACTOR; MKL2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; VIRUS DNA;

ANTIMICROBIAL ACTIVITY; BLOOD; CLONAL GROWTH; CLONE; GENETIC ENGINEERING; GENOME; HUMAN IMMUNODEFICIENCY VIRUS; PERSISTENCE;

ANTIVIRAL THERAPY; ARTICLE; CD4+ T LYMPHOCYTE; CELL CLONE; CELL EXPANSION; EXON; GENE INSERTION; GENE ONTOLOGY; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN CELL; HUMAN GENOME; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INTRON; LONG TERM CARE; PERIPHERAL BLOOD MONONUCLEAR CELL; PERIPHERAL LYMPHOCYTE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TREATMENT DURATION; VIRUS DNA CELL DNA INTERACTION; GENETICS; METABOLISM; PHYSIOLOGY; VIROLOGY; VIRUS LATENCY;

ANTI-RETROVIRAL AGENTS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CLONE CELLS; DNA, VIRAL; GENOME, HUMAN; HIV; HIV INFECTIONS; HUMANS; RNA, VIRAL; TRANSCRIPTION FACTORS; VIRUS INTEGRATION; VIRUS LATENCY;

EID: 84904115855     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.1254194     Document Type: Article

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