Suv39H1 and HP1γ are responsible for chromatin-mediated HIV-1 transcriptional silencing and post-integration latency

EMBO Journal

Volumn 26, Issue 2, 2007, Pages 424-435

  Chéné, Isaure Du ^a   Basyuk, Euguenia ^b   Lin, Yea Lih ^a   Triboulet, Robinson ^a   Knezevich, Anna ^c   Chable Bessia, Christine ^a   Mettling, Clement ^a   Baillat, Vincent ^b   Reynes, Jacques ^b   Corbeau, Pierre ^a   Bertrand, Edouard ^b   Marcello, Alessandro ^c   Emiliani, Stephane ^d   Kiernan, Rosemary ^a   Benkirane, Monsef ^a  

^a INSTITUTE OF HUMAN GENETICS   (France)

^b INSTITUT DE GÉNÉTIQUE MOLÉCULAIRE DE MONTPELLIER   (France)

^c INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^d INSTITUT COCHIN   (France)

Author keywords

Chromatin; HIV; Latency; Reactivation; Transcription

Indexed keywords

ENZYME SUV39H1; HISTONE; METHYLTRANSFERASE; UNCLASSIFIED DRUG; CELL CYCLE PROTEIN; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; HP1GAMMA PROTEIN, HUMAN; NONHISTONE PROTEIN; P300-CBP-ASSOCIATED FACTOR; POSITIVE TRANSCRIPTION ELONGATION FACTOR B; REPRESSOR PROTEIN; SUV39H1 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SP1;

ARTICLE; CHROMATIN; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE REPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LONG TERMINAL REPEAT; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; TRANSCRIPTION INITIATION; VIRUS DNA CELL DNA INTERACTION; VIRUS TRANSCRIPTION; BIOLOGICAL MODEL; CELL CULTURE; GENETIC TRANSCRIPTION; HELA CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LEUKEMIA CELL LINE; METABOLISM; PHYSIOLOGY; TRANSACTIVATION; VIRUS LATENCY;

HUMAN IMMUNODEFICIENCY VIRUS 1;

CELL CYCLE PROTEINS; CELLS, CULTURED; CHROMATIN; CHROMOSOMAL PROTEINS, NON-HISTONE; GENE SILENCING; HELA CELLS; HISTONE ACETYLTRANSFERASES; HISTONE-LYSINE N-METHYLTRANSFERASE; HISTONES; HIV LONG TERMINAL REPEAT; HIV-1; HUMANS; JURKAT CELLS; METHYLTRANSFERASES; MODELS, BIOLOGICAL; POSITIVE TRANSCRIPTIONAL ELONGATION FACTOR B; REPRESSOR PROTEINS; SP1 TRANSCRIPTION FACTOR; TRANS-ACTIVATION (GENETICS); TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; VIRUS INTEGRATION; VIRUS LATENCY;

EID: 33846506800     PISSN: 02614189     EISSN: 14602075     Source Type: Journal    
DOI: 10.1038/sj.emboj.7601517     Document Type: Article

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