-
1
-
-
84874189388
-
Caspase-11 protects against bacteria that escape the vacuole
-
Aachoui Y., Leaf I.A., Hagar J.A., Fontana M.F., Campos C.G., Zak D.E., Tan M.H., Cotter P.A., Vance R.E., Aderem A., Miao E.A. Caspase-11 protects against bacteria that escape the vacuole. Science 2013, 339:975-978.
-
(2013)
Science
, vol.339
, pp. 975-978
-
-
Aachoui, Y.1
Leaf, I.A.2
Hagar, J.A.3
Fontana, M.F.4
Campos, C.G.5
Zak, D.E.6
Tan, M.H.7
Cotter, P.A.8
Vance, R.E.9
Aderem, A.10
Miao, E.A.11
-
2
-
-
84906852294
-
Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-is required for inflammasome priming
-
Allam R., Lawlor K.E., Yu E.C., Mildenhall A.L., Moujalled D.M., Lewis R.S., Ke F., Mason K.D., White M.J., Stacey K.J., et al. Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-is required for inflammasome priming. EMBO Rep. 2014, 15:982-990.
-
(2014)
EMBO Rep.
, vol.15
, pp. 982-990
-
-
Allam, R.1
Lawlor, K.E.2
Yu, E.C.3
Mildenhall, A.L.4
Moujalled, D.M.5
Lewis, R.S.6
Ke, F.7
Mason, K.D.8
White, M.J.9
Stacey, K.J.10
-
3
-
-
0023663870
-
A cell that dies during wild-type C. elegans development can function as a neuron in a ced-mutant
-
Avery L., Horvitz H.R. A cell that dies during wild-type C. elegans development can function as a neuron in a ced-mutant. Cell 1987, 51:1071-1078.
-
(1987)
Cell
, vol.51
, pp. 1071-1078
-
-
Avery, L.1
Horvitz, H.R.2
-
4
-
-
84943199941
-
NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-and caspase-5
-
Baker P.J., Boucher D., Bierschenk D., Tebartz C., Whitney P.G., D'Silva D.B., Tanzer M.C., Monteleone M., Robertson A.A., Cooper M.A., et al. NLRP3 inflammasome activation downstream of cytoplasmic LPS recognition by both caspase-and caspase-5. Eur. J. Immunol. 2015, 45:2918-2926.
-
(2015)
Eur. J. Immunol.
, vol.45
, pp. 2918-2926
-
-
Baker, P.J.1
Boucher, D.2
Bierschenk, D.3
Tebartz, C.4
Whitney, P.G.5
D'Silva, D.B.6
Tanzer, M.C.7
Monteleone, M.8
Robertson, A.A.9
Cooper, M.A.10
-
5
-
-
43049159536
-
Transcription of the caspase-14 gene in human epidermal keratinocytes requires AP-and NFkappaB
-
Ballaun C., Karner S., Mrass P., Mildner M., Buchberger M., Bach J., Ban J., Harant H., Tschachler E., Eckhart L. Transcription of the caspase-14 gene in human epidermal keratinocytes requires AP-and NFkappaB. Biochem. Biophys. Res. Commun. 2008, 371:261-266.
-
(2008)
Biochem. Biophys. Res. Commun.
, vol.371
, pp. 261-266
-
-
Ballaun, C.1
Karner, S.2
Mrass, P.3
Mildner, M.4
Buchberger, M.5
Bach, J.6
Ban, J.7
Harant, H.8
Tschachler, E.9
Eckhart, L.10
-
6
-
-
40849140977
-
Glucocorticoid receptor is required for skin barrier competence
-
Bayo P., Sanchis A., Bravo A., Cascallana J.L., Buder K., Tuckermann J., Schütz G., Pérez P. Glucocorticoid receptor is required for skin barrier competence. Endocrinology 2008, 149:1377-1388.
-
(2008)
Endocrinology
, vol.149
, pp. 1377-1388
-
-
Bayo, P.1
Sanchis, A.2
Bravo, A.3
Cascallana, J.L.4
Buder, K.5
Tuckermann, J.6
Schütz, G.7
Pérez, P.8
-
7
-
-
84896801592
-
Extracellular caspase-drives murine inflammatory pain via microglial TNF-α secretion
-
Berta T., Park C.K., Xu Z.Z., Xie R.G., Liu T., Lü N., Liu Y.C., Ji R.R. Extracellular caspase-drives murine inflammatory pain via microglial TNF-α secretion. J. Clin. Invest. 2014, 124:1173-1186.
-
(2014)
J. Clin. Invest.
, vol.124
, pp. 1173-1186
-
-
Berta, T.1
Park, C.K.2
Xu, Z.Z.3
Xie, R.G.4
Liu, T.5
Lü, N.6
Liu, Y.C.7
Ji, R.R.8
-
8
-
-
8644274867
-
Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo
-
Bondanza A., Zimmermann V.S., Rovere-Querini P., Turnay J., Dumitriu I.E., Stach C.M., Voll R.E., Gaipl U.S., Bertling W., Pöschl E., et al. Inhibition of phosphatidylserine recognition heightens the immunogenicity of irradiated lymphoma cells in vivo. J. Exp. Med. 2004, 200:1157-1165.
-
(2004)
J. Exp. Med.
, vol.200
, pp. 1157-1165
-
-
Bondanza, A.1
Zimmermann, V.S.2
Rovere-Querini, P.3
Turnay, J.4
Dumitriu, I.E.5
Stach, C.M.6
Voll, R.E.7
Gaipl, U.S.8
Bertling, W.9
Pöschl, E.10
-
9
-
-
84871125002
-
Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-in an RIP3-independent manner
-
Bossaller L., Chiang P.I., Schmidt-Lauber C., Ganesan S., Kaiser W.J., Rathinam V.A., Mocarski E.S., Subramanian D., Green D.R., Silverman N., et al. Cutting edge: FAS (CD95) mediates noncanonical IL-1β and IL-18 maturation via caspase-in an RIP3-independent manner. J. Immunol. 2012, 189:5508-5512.
-
(2012)
J. Immunol.
, vol.189
, pp. 5508-5512
-
-
Bossaller, L.1
Chiang, P.I.2
Schmidt-Lauber, C.3
Ganesan, S.4
Kaiser, W.J.5
Rathinam, V.A.6
Mocarski, E.S.7
Subramanian, D.8
Green, D.R.9
Silverman, N.10
-
10
-
-
84941652089
-
Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage
-
Bronner D.N., Abuaita B.H., Chen X., Fitzgerald K.A., Nuñez G., He Y., Yin X.M., O'Riordan M.X. Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage. Immunity 2015, 43:451-462.
-
(2015)
Immunity
, vol.43
, pp. 451-462
-
-
Bronner, D.N.1
Abuaita, B.H.2
Chen, X.3
Fitzgerald, K.A.4
Nuñez, G.5
He, Y.6
Yin, X.M.7
O'Riordan, M.X.8
-
11
-
-
84867333450
-
Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
-
Broz P., Ruby T., Belhocine K., Bouley D.M., Kayagaki N., Dixit V.M., Monack D.M. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 2012, 490:288-291.
-
(2012)
Nature
, vol.490
, pp. 288-291
-
-
Broz, P.1
Ruby, T.2
Belhocine, K.3
Bouley, D.M.4
Kayagaki, N.5
Dixit, V.M.6
Monack, D.M.7
-
12
-
-
84930225289
-
Human caspase-mediates noncanonical inflammasome activation against gram-negative bacterial pathogens
-
Casson C.N., Yu J., Reyes V.M., Taschuk F.O., Yadav A., Copenhaver A.M., Nguyen H.T., Collman R.G., Shin S. Human caspase-mediates noncanonical inflammasome activation against gram-negative bacterial pathogens. Proc. Natl. Acad. Sci. USA 2015, 112:6688-6693.
-
(2015)
Proc. Natl. Acad. Sci. USA
, vol.112
, pp. 6688-6693
-
-
Casson, C.N.1
Yu, J.2
Reyes, V.M.3
Taschuk, F.O.4
Yadav, A.5
Copenhaver, A.M.6
Nguyen, H.T.7
Collman, R.G.8
Shin, S.9
-
13
-
-
84920950343
-
IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
-
Cayrol C., Girard J.P. IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr. Opin. Immunol. 2014, 31:31-37.
-
(2014)
Curr. Opin. Immunol.
, vol.31
, pp. 31-37
-
-
Cayrol, C.1
Girard, J.P.2
-
14
-
-
84937577488
-
Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis
-
Cullen S.P., Kearney C.J., Clancy D.M., Martin S.J. Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis. Cell Rep. 2015, 11:1535-1548.
-
(2015)
Cell Rep.
, vol.11
, pp. 1535-1548
-
-
Cullen, S.P.1
Kearney, C.J.2
Clancy, D.M.3
Martin, S.J.4
-
15
-
-
10644288480
-
Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis
-
Daish T.J., Mills K., Kumar S. Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. Dev. Cell 2004, 7:909-915.
-
(2004)
Dev. Cell
, vol.7
, pp. 909-915
-
-
Daish, T.J.1
Mills, K.2
Kumar, S.3
-
16
-
-
34447570932
-
Caspase-14 protects against epidermal UVB photodamage and water loss
-
Denecker G., Hoste E., Gilbert B., Hochepied T., Ovaere P., Lippens S., Van den Broecke C., Van Damme P., D'Herde K., Hachem J.P., et al. Caspase-14 protects against epidermal UVB photodamage and water loss. Nat. Cell Biol. 2007, 9:666-674.
-
(2007)
Nat. Cell Biol.
, vol.9
, pp. 666-674
-
-
Denecker, G.1
Hoste, E.2
Gilbert, B.3
Hochepied, T.4
Ovaere, P.5
Lippens, S.6
Van den Broecke, C.7
Van Damme, P.8
D'Herde, K.9
Hachem, J.P.10
-
17
-
-
84861712290
-
Survival function of the FADD-CASPASE-8-cFLIP(L) complex
-
Dillon C.P., Oberst A., Weinlich R., Janke L.J., Kang T.B., Ben-Moshe T., Mak T.W., Wallach D., Green D.R. Survival function of the FADD-CASPASE-8-cFLIP(L) complex. Cell Rep. 2012, 1:401-407.
-
(2012)
Cell Rep.
, vol.1
, pp. 401-407
-
-
Dillon, C.P.1
Oberst, A.2
Weinlich, R.3
Janke, L.J.4
Kang, T.B.5
Ben-Moshe, T.6
Mak, T.W.7
Wallach, D.8
Green, D.R.9
-
18
-
-
46649096691
-
Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire
-
Eckhart L., Ballaun C., Hermann M., VandeBerg J.L., Sipos W., Uthman A., Fischer H., Tschachler E. Identification of novel mammalian caspases reveals an important role of gene loss in shaping the human caspase repertoire. Mol. Biol. Evol. 2008, 25:831-841.
-
(2008)
Mol. Biol. Evol.
, vol.25
, pp. 831-841
-
-
Eckhart, L.1
Ballaun, C.2
Hermann, M.3
VandeBerg, J.L.4
Sipos, W.5
Uthman, A.6
Fischer, H.7
Tschachler, E.8
-
19
-
-
1942444411
-
Identification of genes involved in apoptosis and dominant follicle development during follicular waves in cattle
-
Evans A.C., Ireland J.L., Winn M.E., Lonergan P., Smith G.W., Coussens P.M., Ireland J.J. Identification of genes involved in apoptosis and dominant follicle development during follicular waves in cattle. Biol. Reprod. 2004, 70:1475-1484.
-
(2004)
Biol. Reprod.
, vol.70
, pp. 1475-1484
-
-
Evans, A.C.1
Ireland, J.L.2
Winn, M.E.3
Lonergan, P.4
Smith, G.W.5
Coussens, P.M.6
Ireland, J.J.7
-
20
-
-
0344053451
-
In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains
-
Fernandes-Alnemri T., Armstrong R.C., Krebs J., Srinivasula S.M., Wang L., Bullrich F., Fritz L.C., Trapani J.A., Tomaselli K.J., Litwack G., Alnemri E.S. In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains. Proc. Natl. Acad. Sci. USA 1996, 93:7464-7469.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7464-7469
-
-
Fernandes-Alnemri, T.1
Armstrong, R.C.2
Krebs, J.3
Srinivasula, S.M.4
Wang, L.5
Bullrich, F.6
Fritz, L.C.7
Trapani, J.A.8
Tomaselli, K.J.9
Litwack, G.10
Alnemri, E.S.11
-
21
-
-
84885459019
-
Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome
-
Fernandes-Alnemri T., Kang S., Anderson C., Sagara J., Fitzgerald K.A., Alnemri E.S. Cutting edge: TLR signaling licenses IRAK1 for rapid activation of the NLRP3 inflammasome. J. Immunol. 2013, 191:3995-3999.
-
(2013)
J. Immunol.
, vol.191
, pp. 3995-3999
-
-
Fernandes-Alnemri, T.1
Kang, S.2
Anderson, C.3
Sagara, J.4
Fitzgerald, K.A.5
Alnemri, E.S.6
-
22
-
-
0036294646
-
Human caspase 12 has acquired deleterious mutations
-
Fischer H., Koenig U., Eckhart L., Tschachler E. Human caspase 12 has acquired deleterious mutations. Biochem. Biophys. Res. Commun. 2002, 293:722-726.
-
(2002)
Biochem. Biophys. Res. Commun.
, vol.293
, pp. 722-726
-
-
Fischer, H.1
Koenig, U.2
Eckhart, L.3
Tschachler, E.4
-
23
-
-
77951673268
-
TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
-
Freeman G.J., Casasnovas J.M., Umetsu D.T., DeKruyff R.H. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 2010, 235:172-189.
-
(2010)
Immunol. Rev.
, vol.235
, pp. 172-189
-
-
Freeman, G.J.1
Casasnovas, J.M.2
Umetsu, D.T.3
DeKruyff, R.H.4
-
24
-
-
81055125652
-
Programmed cell death in animal development and disease
-
Fuchs Y., Steller H. Programmed cell death in animal development and disease. Cell 2011, 147:742-758.
-
(2011)
Cell
, vol.147
, pp. 742-758
-
-
Fuchs, Y.1
Steller, H.2
-
26
-
-
84255210700
-
Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012
-
Galluzzi L., Vitale I., Abrams J.M., Alnemri E.S., Baehrecke E.H., Blagosklonny M.V., Dawson T.M., Dawson V.L., El-Deiry W.S., Fulda S., et al. Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012. Cell Death Differ. 2012, 19:107-120.
-
(2012)
Cell Death Differ.
, vol.19
, pp. 107-120
-
-
Galluzzi, L.1
Vitale, I.2
Abrams, J.M.3
Alnemri, E.S.4
Baehrecke, E.H.5
Blagosklonny, M.V.6
Dawson, T.M.7
Dawson, V.L.8
El-Deiry, W.S.9
Fulda, S.10
-
28
-
-
84908703421
-
Molecular mechanisms of regulated necrosis
-
Galluzzi L., Kepp O., Krautwald S., Kroemer G., Linkermann A. Molecular mechanisms of regulated necrosis. Semin. Cell Dev. Biol. 2014, 35:24-32.
-
(2014)
Semin. Cell Dev. Biol.
, vol.35
, pp. 24-32
-
-
Galluzzi, L.1
Kepp, O.2
Krautwald, S.3
Kroemer, G.4
Linkermann, A.5
-
29
-
-
84939986310
-
Essential versus accessory aspects of cell death: recommendations of the NCCD 2015
-
Galluzzi L., Bravo-San Pedro J.M., Vitale I., Aaronson S.A., Abrams J.M., Adam D., Alnemri E.S., Altucci L., Andrews D., Annicchiarico-Petruzzelli M., et al. Essential versus accessory aspects of cell death: recommendations of the NCCD 2015. Cell Death Differ. 2015, 22:58-73.
-
(2015)
Cell Death Differ.
, vol.22
, pp. 58-73
-
-
Galluzzi, L.1
Bravo-San Pedro, J.M.2
Vitale, I.3
Aaronson, S.A.4
Abrams, J.M.5
Adam, D.6
Alnemri, E.S.7
Altucci, L.8
Andrews, D.9
Annicchiarico-Petruzzelli, M.10
-
30
-
-
84926252071
-
Autophagy in malignant transformation and cancer progression
-
Galluzzi L., Pietrocola F., Bravo-San Pedro J.M., Amaravadi R.K., Baehrecke E.H., Cecconi F., Codogno P., Debnath J., Gewirtz D.A., Karantza V., et al. Autophagy in malignant transformation and cancer progression. EMBO J. 2015, 34:856-880.
-
(2015)
EMBO J.
, vol.34
, pp. 856-880
-
-
Galluzzi, L.1
Pietrocola, F.2
Bravo-San Pedro, J.M.3
Amaravadi, R.K.4
Baehrecke, E.H.5
Cecconi, F.6
Codogno, P.7
Debnath, J.8
Gewirtz, D.A.9
Karantza, V.10
-
31
-
-
0031004174
-
Caspase-processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production
-
Ghayur T., Banerjee S., Hugunin M., Butler D., Herzog L., Carter A., Quintal L., Sekut L., Talanian R., Paskind M., et al. Caspase-processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 1997, 386:619-623.
-
(1997)
Nature
, vol.386
, pp. 619-623
-
-
Ghayur, T.1
Banerjee, S.2
Hugunin, M.3
Butler, D.4
Herzog, L.5
Carter, A.6
Quintal, L.7
Sekut, L.8
Talanian, R.9
Paskind, M.10
-
32
-
-
15644369352
-
Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme
-
Gu Y., Kuida K., Tsutsui H., Ku G., Hsiao K., Fleming M.A., Hayashi N., Higashino K., Okamura H., Nakanishi K., et al. Activation of interferon-gamma inducing factor mediated by interleukin-1beta converting enzyme. Science 1997, 275:206-209.
-
(1997)
Science
, vol.275
, pp. 206-209
-
-
Gu, Y.1
Kuida, K.2
Tsutsui, H.3
Ku, G.4
Hsiao, K.5
Fleming, M.A.6
Hayashi, N.7
Higashino, K.8
Okamura, H.9
Nakanishi, K.10
-
33
-
-
84883790050
-
Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock
-
Hagar J.A., Powell D.A., Aachoui Y., Ernst R.K., Miao E.A. Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock. Science 2013, 341:1250-1253.
-
(2013)
Science
, vol.341
, pp. 1250-1253
-
-
Hagar, J.A.1
Powell, D.A.2
Aachoui, Y.3
Ernst, R.K.4
Miao, E.A.5
-
34
-
-
65249137687
-
A tumor suppressor function for caspase-2
-
Ho L.H., Taylor R., Dorstyn L., Cakouros D., Bouillet P., Kumar S. A tumor suppressor function for caspase-2. Proc. Natl. Acad. Sci. USA 2009, 106:5336-5341.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 5336-5341
-
-
Ho, L.H.1
Taylor, R.2
Dorstyn, L.3
Cakouros, D.4
Bouillet, P.5
Kumar, S.6
-
35
-
-
12444275550
-
Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo
-
Hoffmann P.R., Kench J.A., Vondracek A., Kruk E., Daleke D.L., Jordan M., Marrack P., Henson P.M., Fadok V.A. Interaction between phosphatidylserine and the phosphatidylserine receptor inhibits immune responses in vivo. J. Immunol. 2005, 174:1393-1404.
-
(2005)
J. Immunol.
, vol.174
, pp. 1393-1404
-
-
Hoffmann, P.R.1
Kench, J.A.2
Vondracek, A.3
Kruk, E.4
Daleke, D.L.5
Jordan, M.6
Marrack, P.7
Henson, P.M.8
Fadok, V.A.9
-
36
-
-
79960127640
-
Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy
-
Huang Q., Li F., Liu X., Li W., Shi W., Liu F.F., O'Sullivan B., He Z., Peng Y., Tan A.C., et al. Caspase 3-mediated stimulation of tumor cell repopulation during cancer radiotherapy. Nat. Med. 2011, 17:860-866.
-
(2011)
Nat. Med.
, vol.17
, pp. 860-866
-
-
Huang, Q.1
Li, F.2
Liu, X.3
Li, W.4
Shi, W.5
Liu, F.F.6
O'Sullivan, B.7
He, Z.8
Peng, Y.9
Tan, A.C.10
-
37
-
-
84874263775
-
Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
-
Kaczmarek A., Vandenabeele P., Krysko D.V. Necroptosis: The release of damage-associated molecular patterns and its physiological relevance. Immunity 2013, 38:209-223.
-
(2013)
Immunity
, vol.38
, pp. 209-223
-
-
Kaczmarek, A.1
Vandenabeele, P.2
Krysko, D.V.3
-
38
-
-
79952811804
-
RIP3 mediates the embryonic lethality of caspase-8-deficient mice
-
Kaiser W.J., Upton J.W., Long A.B., Livingston-Rosanoff D., Daley-Bauer L.P., Hakem R., Caspary T., Mocarski E.S. RIP3 mediates the embryonic lethality of caspase-8-deficient mice. Nature 2011, 471:368-372.
-
(2011)
Nature
, vol.471
, pp. 368-372
-
-
Kaiser, W.J.1
Upton, J.W.2
Long, A.B.3
Livingston-Rosanoff, D.4
Daley-Bauer, L.P.5
Hakem, R.6
Caspary, T.7
Mocarski, E.S.8
-
39
-
-
84872764927
-
Caspase-blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
-
Kang T.B., Yang S.H., Toth B., Kovalenko A., Wallach D. Caspase-blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 2013, 38:27-40.
-
(2013)
Immunity
, vol.38
, pp. 27-40
-
-
Kang, T.B.1
Yang, S.H.2
Toth, B.3
Kovalenko, A.4
Wallach, D.5
-
40
-
-
84932601454
-
Caspase-scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3
-
Kang S., Fernandes-Alnemri T., Rogers C., Mayes L., Wang Y., Dillon C., Roback L., Kaiser W., Oberst A., Sagara J., et al. Caspase-scaffolding function and MLKL regulate NLRP3 inflammasome activation downstream of TLR3. Nat. Commun. 2015, 6:7515.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7515
-
-
Kang, S.1
Fernandes-Alnemri, T.2
Rogers, C.3
Mayes, L.4
Wang, Y.5
Dillon, C.6
Roback, L.7
Kaiser, W.8
Oberst, A.9
Sagara, J.10
-
41
-
-
80455176839
-
Non-canonical inflammasome activation targets caspase-11
-
Kayagaki N., Warming S., Lamkanfi M., Vande Walle L., Louie S., Dong J., Newton K., Qu Y., Liu J., Heldens S., et al. Non-canonical inflammasome activation targets caspase-11. Nature 2011, 479:117-121.
-
(2011)
Nature
, vol.479
, pp. 117-121
-
-
Kayagaki, N.1
Warming, S.2
Lamkanfi, M.3
Vande Walle, L.4
Louie, S.5
Dong, J.6
Newton, K.7
Qu, Y.8
Liu, J.9
Heldens, S.10
-
42
-
-
84883775365
-
Noncanonical inflammasome activation by intracellular LPS independent of TLR4
-
Kayagaki N., Wong M.T., Stowe I.B., Ramani S.R., Gonzalez L.C., Akashi-Takamura S., Miyake K., Zhang J., Lee W.P., Muszyński A., et al. Noncanonical inflammasome activation by intracellular LPS independent of TLR4. Science 2013, 341:1246-1249.
-
(2013)
Science
, vol.341
, pp. 1246-1249
-
-
Kayagaki, N.1
Wong, M.T.2
Stowe, I.B.3
Ramani, S.R.4
Gonzalez, L.C.5
Akashi-Takamura, S.6
Miyake, K.7
Zhang, J.8
Lee, W.P.9
Muszyński, A.10
-
43
-
-
84942856523
-
Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
-
Kayagaki N., Stowe I.B., Lee B.L., O'Rourke K., Anderson K., Warming S., Cuellar T., Haley B., Roose-Girma M., Phung Q.T., et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 2015, 526:666-671.
-
(2015)
Nature
, vol.526
, pp. 666-671
-
-
Kayagaki, N.1
Stowe, I.B.2
Lee, B.L.3
O'Rourke, K.4
Anderson, K.5
Warming, S.6
Cuellar, T.7
Haley, B.8
Roose-Girma, M.9
Phung, Q.T.10
-
44
-
-
84859464225
-
An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1
-
Kenneth N.S., Younger J.M., Hughes E.D., Marcotte D., Barker P.A., Saunders T.L., Duckett C.S. An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem. J. 2012, 443:355-359.
-
(2012)
Biochem. J.
, vol.443
, pp. 355-359
-
-
Kenneth, N.S.1
Younger, J.M.2
Hughes, E.D.3
Marcotte, D.4
Barker, P.A.5
Saunders, T.L.6
Duckett, C.S.7
-
45
-
-
84923247523
-
Consensus guidelines for the detection of immunogenic cell death
-
Kepp O., Senovilla L., Vitale I., Vacchelli E., Adjemian S., Agostinis P., Apetoh L., Aranda F., Barnaba V., Bloy N., et al. Consensus guidelines for the detection of immunogenic cell death. OncoImmunology 2014, 3:e955691.
-
(2014)
OncoImmunology
, vol.3
, pp. e955691
-
-
Kepp, O.1
Senovilla, L.2
Vitale, I.3
Vacchelli, E.4
Adjemian, S.5
Agostinis, P.6
Apetoh, L.7
Aranda, F.8
Barnaba, V.9
Bloy, N.10
-
46
-
-
84893004962
-
Caspase-and RasGAP: A stress-sensing survival/demise switch
-
Khalil H., Bertrand M.J., Vandenabeele P., Widmann C. Caspase-and RasGAP: A stress-sensing survival/demise switch. Trends Cell Biol. 2014, 24:83-89.
-
(2014)
Trends Cell Biol.
, vol.24
, pp. 83-89
-
-
Khalil, H.1
Bertrand, M.J.2
Vandenabeele, P.3
Widmann, C.4
-
47
-
-
79251585912
-
Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-receptor-associated kinase-M
-
Kobayashi H., Nolan A., Naveed B., Hoshino Y., Segal L.N., Fujita Y., Rom W.N., Weiden M.D. Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-receptor-associated kinase-M. J. Immunol. 2011, 186:403-410.
-
(2011)
J. Immunol.
, vol.186
, pp. 403-410
-
-
Kobayashi, H.1
Nolan, A.2
Naveed, B.3
Hoshino, Y.4
Segal, L.N.5
Fujita, Y.6
Rom, W.N.7
Weiden, M.D.8
-
48
-
-
70350484946
-
Caspase-deficiency in epidermal keratinocytes triggers an inflammatory skin disease
-
Kovalenko A., Kim J.C., Kang T.B., Rajput A., Bogdanov K., Dittrich-Breiholz O., Kracht M., Brenner O., Wallach D. Caspase-deficiency in epidermal keratinocytes triggers an inflammatory skin disease. J. Exp. Med. 2009, 206:2161-2177.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 2161-2177
-
-
Kovalenko, A.1
Kim, J.C.2
Kang, T.B.3
Rajput, A.4
Bogdanov, K.5
Dittrich-Breiholz, O.6
Kracht, M.7
Brenner, O.8
Wallach, D.9
-
49
-
-
14044251695
-
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
-
Kroemer G. Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution. Cell Death Differ. 1997, 4:443-456.
-
(1997)
Cell Death Differ.
, vol.4
, pp. 443-456
-
-
Kroemer, G.1
-
50
-
-
84875552922
-
Immunogenic cell death in cancer therapy
-
Kroemer G., Galluzzi L., Kepp O., Zitvogel L. Immunogenic cell death in cancer therapy. Annu. Rev. Immunol. 2013, 31:51-72.
-
(2013)
Annu. Rev. Immunol.
, vol.31
, pp. 51-72
-
-
Kroemer, G.1
Galluzzi, L.2
Kepp, O.3
Zitvogel, L.4
-
51
-
-
84905376844
-
The skin microbiome of caspase-14-deficient mice shows mild dysbiosis
-
Kubica M., Hildebrand F., Brinkman B.M., Goossens D., Del Favero J., Vercammen K., Cornelis P., Schröder J.M., Vandenabeele P., Raes J., Declercq W. The skin microbiome of caspase-14-deficient mice shows mild dysbiosis. Exp. Dermatol. 2014, 23:561-567.
-
(2014)
Exp. Dermatol.
, vol.23
, pp. 561-567
-
-
Kubica, M.1
Hildebrand, F.2
Brinkman, B.M.3
Goossens, D.4
Del Favero, J.5
Vercammen, K.6
Cornelis, P.7
Schröder, J.M.8
Vandenabeele, P.9
Raes, J.10
Declercq, W.11
-
52
-
-
0029956641
-
Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice
-
Kuida K., Zheng T.S., Na S., Kuan C., Yang D., Karasuyama H., Rakic P., Flavell R.A. Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice. Nature 1996, 384:368-372.
-
(1996)
Nature
, vol.384
, pp. 368-372
-
-
Kuida, K.1
Zheng, T.S.2
Na, S.3
Kuan, C.4
Yang, D.5
Karasuyama, H.6
Rakic, P.7
Flavell, R.A.8
-
53
-
-
0032493910
-
Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9
-
Kuida K., Haydar T.F., Kuan C.Y., Gu Y., Taya C., Karasuyama H., Su M.S., Rakic P., Flavell R.A. Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9. Cell 1998, 94:325-337.
-
(1998)
Cell
, vol.94
, pp. 325-337
-
-
Kuida, K.1
Haydar, T.F.2
Kuan, C.Y.3
Gu, Y.4
Taya, C.5
Karasuyama, H.6
Su, M.S.7
Rakic, P.8
Flavell, R.A.9
-
54
-
-
0027990778
-
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-and the mammalian IL-beta-converting enzyme
-
Kumar S., Kinoshita M., Noda M., Copeland N.G., Jenkins N.A. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-and the mammalian IL-beta-converting enzyme. Genes Dev. 1994, 8:1613-1626.
-
(1994)
Genes Dev.
, vol.8
, pp. 1613-1626
-
-
Kumar, S.1
Kinoshita, M.2
Noda, M.3
Copeland, N.G.4
Jenkins, N.A.5
-
55
-
-
78149487761
-
Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling
-
Labbé K., Miu J., Yeretssian G., Serghides L., Tam M., Finney C.A., Erdman L.K., Goulet M.L., Kain K.C., Stevenson M.M., Saleh M. Caspase-12 dampens the immune response to malaria independently of the inflammasome by targeting NF-kappaB signaling. J. Immunol. 2010, 185:5495-5502.
-
(2010)
J. Immunol.
, vol.185
, pp. 5495-5502
-
-
Labbé, K.1
Miu, J.2
Yeretssian, G.3
Serghides, L.4
Tam, M.5
Finney, C.A.6
Erdman, L.K.7
Goulet, M.L.8
Kain, K.C.9
Stevenson, M.M.10
Saleh, M.11
-
56
-
-
32444434664
-
Caspases 3 and 7: key mediators of mitochondrial events of apoptosis
-
Lakhani S.A., Masud A., Kuida K., Porter G.A., Booth C.J., Mehal W.Z., Inayat I., Flavell R.A. Caspases 3 and 7: key mediators of mitochondrial events of apoptosis. Science 2006, 311:847-851.
-
(2006)
Science
, vol.311
, pp. 847-851
-
-
Lakhani, S.A.1
Masud, A.2
Kuida, K.3
Porter, G.A.4
Booth, C.J.5
Mehal, W.Z.6
Inayat, I.7
Flavell, R.A.8
-
57
-
-
84901310586
-
Mechanisms and functions of inflammasomes
-
Lamkanfi M., Dixit V.M. Mechanisms and functions of inflammasomes. Cell 2014, 157:1013-1022.
-
(2014)
Cell
, vol.157
, pp. 1013-1022
-
-
Lamkanfi, M.1
Dixit, V.M.2
-
58
-
-
0038820117
-
Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal
-
Lauber K., Bohn E., Kröber S.M., Xiao Y.J., Blumenthal S.G., Lindemann R.K., Marini P., Wiedig C., Zobywalski A., Baksh S., et al. Apoptotic cells induce migration of phagocytes via caspase-3-mediated release of a lipid attraction signal. Cell 2003, 113:717-730.
-
(2003)
Cell
, vol.113
, pp. 717-730
-
-
Lauber, K.1
Bohn, E.2
Kröber, S.M.3
Xiao, Y.J.4
Blumenthal, S.G.5
Lindemann, R.K.6
Marini, P.7
Wiedig, C.8
Zobywalski, A.9
Baksh, S.10
-
59
-
-
40149084641
-
Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity
-
LeBlanc P.M., Yeretssian G., Rutherford N., Doiron K., Nadiri A., Zhu L., Green D.R., Gruenheid S., Saleh M. Caspase-12 modulates NOD signaling and regulates antimicrobial peptide production and mucosal immunity. Cell Host Microbe 2008, 3:146-157.
-
(2008)
Cell Host Microbe
, vol.3
, pp. 146-157
-
-
LeBlanc, P.M.1
Yeretssian, G.2
Rutherford, N.3
Doiron, K.4
Nadiri, A.5
Zhu, L.6
Green, D.R.7
Gruenheid, S.8
Saleh, M.9
-
60
-
-
63649143438
-
Dynamic expression of epidermal caspase 8 simulates a wound healing response
-
Lee P., Lee D.J., Chan C., Chen S.W., Ch'en I., Jamora C. Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 2009, 458:519-523.
-
(2009)
Nature
, vol.458
, pp. 519-523
-
-
Lee, P.1
Lee, D.J.2
Chan, C.3
Chen, S.W.4
Ch'en, I.5
Jamora, C.6
-
61
-
-
84865164564
-
Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection
-
Li X., He Y. Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection. PLoS ONE 2012, 7:e43512.
-
(2012)
PLoS ONE
, vol.7
, pp. e43512
-
-
Li, X.1
He, Y.2
-
62
-
-
0028984948
-
Mice deficient in IL-beta-converting enzyme are defective in production of mature IL-beta and resistant to endotoxic shock
-
Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., et al. Mice deficient in IL-beta-converting enzyme are defective in production of mature IL-beta and resistant to endotoxic shock. Cell 1995, 80:401-411.
-
(1995)
Cell
, vol.80
, pp. 401-411
-
-
Li, P.1
Allen, H.2
Banerjee, S.3
Franklin, S.4
Herzog, L.5
Johnston, C.6
McDowell, J.7
Paskind, M.8
Rodman, L.9
Salfeld, J.10
-
63
-
-
0030715323
-
Cytochrome c and dATP-dependent formation of Apaf-1/caspase-complex initiates an apoptotic protease cascade
-
Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-complex initiates an apoptotic protease cascade. Cell 1997, 91:479-489.
-
(1997)
Cell
, vol.91
, pp. 479-489
-
-
Li, P.1
Nijhawan, D.2
Budihardjo, I.3
Srinivasula, S.M.4
Ahmad, M.5
Alnemri, E.S.6
Wang, X.7
-
64
-
-
0345374586
-
Phosphatidylserine receptor is required for clearance of apoptotic cells
-
Li M.O., Sarkisian M.R., Mehal W.Z., Rakic P., Flavell R.A. Phosphatidylserine receptor is required for clearance of apoptotic cells. Science 2003, 302:1560-1563.
-
(2003)
Science
, vol.302
, pp. 1560-1563
-
-
Li, M.O.1
Sarkisian, M.R.2
Mehal, W.Z.3
Rakic, P.4
Flavell, R.A.5
-
65
-
-
77949847250
-
Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration
-
Li F., Huang Q., Chen J., Peng Y., Roop D.R., Bedford J.S., Li C.Y. Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci. Signal. 2010, 3:ra13.
-
(2010)
Sci. Signal.
, vol.3
, pp. ra13
-
-
Li, F.1
Huang, Q.2
Chen, J.3
Peng, Y.4
Roop, D.R.5
Bedford, J.S.6
Li, C.Y.7
-
66
-
-
17744393424
-
Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing
-
Lippens S., Kockx M., Knaapen M., Mortier L., Polakowska R., Verheyen A., Garmyn M., Zwijsen A., Formstecher P., Huylebroeck D., et al. Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing. Cell Death Differ. 2000, 7:1218-1224.
-
(2000)
Cell Death Differ.
, vol.7
, pp. 1218-1224
-
-
Lippens, S.1
Kockx, M.2
Knaapen, M.3
Mortier, L.4
Polakowska, R.5
Verheyen, A.6
Garmyn, M.7
Zwijsen, A.8
Formstecher, P.9
Huylebroeck, D.10
-
67
-
-
68249137289
-
Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases
-
Lüthi A.U., Cullen S.P., McNeela E.A., Duriez P.J., Afonina I.S., Sheridan C., Brumatti G., Taylor R.C., Kersse K., Vandenabeele P., et al. Suppression of interleukin-33 bioactivity through proteolysis by apoptotic caspases. Immunity 2009, 31:84-98.
-
(2009)
Immunity
, vol.31
, pp. 84-98
-
-
Lüthi, A.U.1
Cullen, S.P.2
McNeela, E.A.3
Duriez, P.J.4
Afonina, I.S.5
Sheridan, C.6
Brumatti, G.7
Taylor, R.C.8
Kersse, K.9
Vandenabeele, P.10
-
68
-
-
51049100571
-
Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8
-
Maelfait J., Vercammen E., Janssens S., Schotte P., Haegman M., Magez S., Beyaert R. Stimulation of Toll-like receptor 3 and 4 induces interleukin-1beta maturation by caspase-8. J. Exp. Med. 2008, 205:1967-1973.
-
(2008)
J. Exp. Med.
, vol.205
, pp. 1967-1973
-
-
Maelfait, J.1
Vercammen, E.2
Janssens, S.3
Schotte, P.4
Haegman, M.5
Magez, S.6
Beyaert, R.7
-
69
-
-
84947416929
-
Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium
-
Maltez V.I., Tubbs A.L., Cook K.D., Aachoui Y., Falcone E.L., Holland S.M., Whitmire J.K., Miao E.A. Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium. Immunity 2015, 43:987-997.
-
(2015)
Immunity
, vol.43
, pp. 987-997
-
-
Maltez, V.I.1
Tubbs, A.L.2
Cook, K.D.3
Aachoui, Y.4
Falcone, E.L.5
Holland, S.M.6
Whitmire, J.K.7
Miao, E.A.8
-
70
-
-
84861435630
-
A perspective on mammalian caspases as positive and negative regulators of inflammation
-
Martin S.J., Henry C.M., Cullen S.P. A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol. Cell 2012, 46:387-397.
-
(2012)
Mol. Cell
, vol.46
, pp. 387-397
-
-
Martin, S.J.1
Henry, C.M.2
Cullen, S.P.3
-
71
-
-
0036671894
-
The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
-
Martinon F., Burns K., Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 2002, 10:417-426.
-
(2002)
Mol. Cell
, vol.10
, pp. 417-426
-
-
Martinon, F.1
Burns, K.2
Tschopp, J.3
-
72
-
-
84923000335
-
Type I interferons in infectious disease
-
McNab F., Mayer-Barber K., Sher A., Wack A., O'Garra A. Type I interferons in infectious disease. Nat. Rev. Immunol. 2015, 15:87-103.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 87-103
-
-
McNab, F.1
Mayer-Barber, K.2
Sher, A.3
Wack, A.4
O'Garra, A.5
-
73
-
-
84922570928
-
A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing
-
Moriwaki K., Bertin J., Gough P.J., Chan F.K. A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing. J. Immunol. 2015, 194:1938-1944.
-
(2015)
J. Immunol.
, vol.194
, pp. 1938-1944
-
-
Moriwaki, K.1
Bertin, J.2
Gough, P.J.3
Chan, F.K.4
-
74
-
-
15844412409
-
FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex
-
Muzio M., Chinnaiyan A.M., Kischkel F.C., O'Rourke K., Shevchenko A., Ni J., Scaffidi C., Bretz J.D., Zhang M., Gentz R., et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex. Cell 1996, 85:817-827.
-
(1996)
Cell
, vol.85
, pp. 817-827
-
-
Muzio, M.1
Chinnaiyan, A.M.2
Kischkel, F.C.3
O'Rourke, K.4
Shevchenko, A.5
Ni, J.6
Scaffidi, C.7
Bretz, J.D.8
Zhang, M.9
Gentz, R.10
-
75
-
-
84902997497
-
Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2
-
O'Brien A.J., Fullerton J.N., Massey K.A., Auld G., Sewell G., James S., Newson J., Karra E., Winstanley A., Alazawi W., et al. Immunosuppression in acutely decompensated cirrhosis is mediated by prostaglandin E2. Nat. Med. 2014, 20:518-523.
-
(2014)
Nat. Med.
, vol.20
, pp. 518-523
-
-
O'Brien, A.J.1
Fullerton, J.N.2
Massey, K.A.3
Auld, G.4
Sewell, G.5
James, S.6
Newson, J.7
Karra, E.8
Winstanley, A.9
Alazawi, W.10
-
76
-
-
79952810024
-
Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis
-
Oberst A., Dillon C.P., Weinlich R., McCormick L.L., Fitzgerald P., Pop C., Hakem R., Salvesen G.S., Green D.R. Catalytic activity of the caspase-8-FLIP(L) complex inhibits RIPK3-dependent necrosis. Nature 2011, 471:363-367.
-
(2011)
Nature
, vol.471
, pp. 363-367
-
-
Oberst, A.1
Dillon, C.P.2
Weinlich, R.3
McCormick, L.L.4
Fitzgerald, P.5
Pop, C.6
Hakem, R.7
Salvesen, G.S.8
Green, D.R.9
-
77
-
-
62049085194
-
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death
-
Panaretakis T., Kepp O., Brockmeier U., Tesniere A., Bjorklund A.C., Chapman D.C., Durchschlag M., Joza N., Pierron G., van Endert P., et al. Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death. EMBO J. 2009, 28:578-590.
-
(2009)
EMBO J.
, vol.28
, pp. 578-590
-
-
Panaretakis, T.1
Kepp, O.2
Brockmeier, U.3
Tesniere, A.4
Bjorklund, A.C.5
Chapman, D.C.6
Durchschlag, M.7
Joza, N.8
Pierron, G.9
van Endert, P.10
-
78
-
-
84901020402
-
Caspase-mediates caspase-processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling
-
Philip N.H., Dillon C.P., Snyder A.G., Fitzgerald P., Wynosky-Dolfi M.A., Zwack E.E., Hu B., Fitzgerald L., Mauldin E.A., Copenhaver A.M., et al. Caspase-mediates caspase-processing and innate immune defense in response to bacterial blockade of NF-κB and MAPK signaling. Proc. Natl. Acad. Sci. USA 2014, 111:7385-7390.
-
(2014)
Proc. Natl. Acad. Sci. USA
, vol.111
, pp. 7385-7390
-
-
Philip, N.H.1
Dillon, C.P.2
Snyder, A.G.3
Fitzgerald, P.4
Wynosky-Dolfi, M.A.5
Zwack, E.E.6
Hu, B.7
Fitzgerald, L.8
Mauldin, E.A.9
Copenhaver, A.M.10
-
79
-
-
84889642140
-
Loss of caspase-augments lymphomagenesis and enhances genomic instability in Atm-deficient mice
-
Puccini J., Shalini S., Voss A.K., Gatei M., Wilson C.H., Hiwase D.K., Lavin M.F., Dorstyn L., Kumar S. Loss of caspase-augments lymphomagenesis and enhances genomic instability in Atm-deficient mice. Proc. Natl. Acad. Sci. USA 2013, 110:19920-19925.
-
(2013)
Proc. Natl. Acad. Sci. USA
, vol.110
, pp. 19920-19925
-
-
Puccini, J.1
Shalini, S.2
Voss, A.K.3
Gatei, M.4
Wilson, C.H.5
Hiwase, D.K.6
Lavin, M.F.7
Dorstyn, L.8
Kumar, S.9
-
80
-
-
84897102291
-
Caspase-11 controls interleukin-1β release through degradation of TRPC1
-
Py B.F., Jin M., Desai B.N., Penumaka A., Zhu H., Kober M., Dietrich A., Lipinski M.M., Henry T., Clapham D.E., Yuan J. Caspase-11 controls interleukin-1β release through degradation of TRPC1. Cell Rep. 2014, 6:1122-1128.
-
(2014)
Cell Rep.
, vol.6
, pp. 1122-1128
-
-
Py, B.F.1
Jin, M.2
Desai, B.N.3
Penumaka, A.4
Zhu, H.5
Kober, M.6
Dietrich, A.7
Lipinski, M.M.8
Henry, T.9
Clapham, D.E.10
Yuan, J.11
-
81
-
-
0034704098
-
An essential role for the caspase dronc in developmentally programmed cell death in Drosophila
-
Quinn L.M., Dorstyn L., Mills K., Colussi P.A., Chen P., Coombe M., Abrams J., Kumar S., Richardson H. An essential role for the caspase dronc in developmentally programmed cell death in Drosophila. J. Biol. Chem. 2000, 275:40416-40424.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 40416-40424
-
-
Quinn, L.M.1
Dorstyn, L.2
Mills, K.3
Colussi, P.A.4
Chen, P.5
Coombe, M.6
Abrams, J.7
Kumar, S.8
Richardson, H.9
-
82
-
-
84919898250
-
Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA
-
Rongvaux A., Jackson R., Harman C.C., Li T., West A.P., de Zoete M.R., Wu Y., Yordy B., Lakhani S.A., Kuan C.Y., et al. Apoptotic caspases prevent the induction of type I interferons by mitochondrial DNA. Cell 2014, 159:1563-1577.
-
(2014)
Cell
, vol.159
, pp. 1563-1577
-
-
Rongvaux, A.1
Jackson, R.2
Harman, C.C.3
Li, T.4
West, A.P.5
de Zoete, M.R.6
Wu, Y.7
Yordy, B.8
Lakhani, S.A.9
Kuan, C.Y.10
-
83
-
-
41949115934
-
Confinement of caspase-12 proteolytic activity to autoprocessing
-
Roy S., Sharom J.R., Houde C., Loisel T.P., Vaillancourt J.P., Shao W., Saleh M., Nicholson D.W. Confinement of caspase-12 proteolytic activity to autoprocessing. Proc. Natl. Acad. Sci. USA 2008, 105:4133-4138.
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 4133-4138
-
-
Roy, S.1
Sharom, J.R.2
Houde, C.3
Loisel, T.P.4
Vaillancourt, J.P.5
Shao, W.6
Saleh, M.7
Nicholson, D.W.8
-
84
-
-
2342457148
-
Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms
-
Saleh M., Vaillancourt J.P., Graham R.K., Huyck M., Srinivasula S.M., Alnemri E.S., Steinberg M.H., Nolan V., Baldwin C.T., Hotchkiss R.S., et al. Differential modulation of endotoxin responsiveness by human caspase-12 polymorphisms. Nature 2004, 429:75-79.
-
(2004)
Nature
, vol.429
, pp. 75-79
-
-
Saleh, M.1
Vaillancourt, J.P.2
Graham, R.K.3
Huyck, M.4
Srinivasula, S.M.5
Alnemri, E.S.6
Steinberg, M.H.7
Nolan, V.8
Baldwin, C.T.9
Hotchkiss, R.S.10
-
85
-
-
33646175602
-
Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice
-
Saleh M., Mathison J.C., Wolinski M.K., Bensinger S.J., Fitzgerald P., Droin N., Ulevitch R.J., Green D.R., Nicholson D.W. Enhanced bacterial clearance and sepsis resistance in caspase-12-deficient mice. Nature 2006, 440:1064-1068.
-
(2006)
Nature
, vol.440
, pp. 1064-1068
-
-
Saleh, M.1
Mathison, J.C.2
Wolinski, M.K.3
Bensinger, S.J.4
Fitzgerald, P.5
Droin, N.6
Ulevitch, R.J.7
Green, D.R.8
Nicholson, D.W.9
-
86
-
-
84901849205
-
Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
-
Segawa K., Kurata S., Yanagihashi Y., Brummelkamp T.R., Matsuda F., Nagata S. Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure. Science 2014, 344:1164-1168.
-
(2014)
Science
, vol.344
, pp. 1164-1168
-
-
Segawa, K.1
Kurata, S.2
Yanagihashi, Y.3
Brummelkamp, T.R.4
Matsuda, F.5
Nagata, S.6
-
87
-
-
84923119242
-
Old, new and emerging functions of caspases
-
Shalini S., Dorstyn L., Dawar S., Kumar S. Old, new and emerging functions of caspases. Cell Death Differ. 2015, 22:526-539.
-
(2015)
Cell Death Differ.
, vol.22
, pp. 526-539
-
-
Shalini, S.1
Dorstyn, L.2
Dawar, S.3
Kumar, S.4
-
88
-
-
84906571225
-
Inflammatory caspases are innate immune receptors for intracellular LPS
-
Shi J., Zhao Y., Wang Y., Gao W., Ding J., Li P., Hu L., Shao F. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014, 514:187-192.
-
(2014)
Nature
, vol.514
, pp. 187-192
-
-
Shi, J.1
Zhao, Y.2
Wang, Y.3
Gao, W.4
Ding, J.5
Li, P.6
Hu, L.7
Shao, F.8
-
89
-
-
84942892037
-
Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
-
Shi J., Zhao Y., Wang K., Shi X., Wang Y., Huang H., Zhuang Y., Cai T., Wang F., Shao F. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 2015, 526:660-665.
-
(2015)
Nature
, vol.526
, pp. 660-665
-
-
Shi, J.1
Zhao, Y.2
Wang, K.3
Shi, X.4
Wang, Y.5
Huang, H.6
Zhuang, Y.7
Cai, T.8
Wang, F.9
Shao, F.10
-
90
-
-
84939482242
-
Organelle-specific initiation of autophagy
-
Sica V., Galluzzi L., Bravo-San Pedro J.M., Izzo V., Maiuri M.C., Kroemer G. Organelle-specific initiation of autophagy. Mol. Cell 2015, 59:522-539.
-
(2015)
Mol. Cell
, vol.59
, pp. 522-539
-
-
Sica, V.1
Galluzzi, L.2
Bravo-San Pedro, J.M.3
Izzo, V.4
Maiuri, M.C.5
Kroemer, G.6
-
91
-
-
84953303735
-
Caspase-12, but not Caspase-11, inhibits obesity and insulin resistance
-
Published online November 18, 2015
-
Skeldon A.M., Morizot A., Douglas T., Santoro N., Kursawe R., Kozlitina J., Caprio S., Mehal W.Z., Saleh M. Caspase-12, but not Caspase-11, inhibits obesity and insulin resistance. J. Immunol. 2016, 196:437-447. Published online November 18, 2015.
-
(2016)
J. Immunol.
, vol.196
, pp. 437-447
-
-
Skeldon, A.M.1
Morizot, A.2
Douglas, T.3
Santoro, N.4
Kursawe, R.5
Kozlitina, J.6
Caprio, S.7
Mehal, W.Z.8
Saleh, M.9
-
92
-
-
0038284956
-
Caspase-mediated processing of the Drosophila NF-kappaB factor Relish
-
Stoven S., Silverman N., Junell A., Hedengren-Olcott M., Erturk D., Engstrom Y., Maniatis T., Hultmark D. Caspase-mediated processing of the Drosophila NF-kappaB factor Relish. Proc. Natl. Acad. Sci. USA 2003, 100:5991-5996.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 5991-5996
-
-
Stoven, S.1
Silverman, N.2
Junell, A.3
Hedengren-Olcott, M.4
Erturk, D.5
Engstrom, Y.6
Maniatis, T.7
Hultmark, D.8
-
93
-
-
84880758440
-
Xk-related protein 8 and CED-promote phosphatidylserine exposure in apoptotic cells
-
Suzuki J., Denning D.P., Imanishi E., Horvitz H.R., Nagata S. Xk-related protein 8 and CED-promote phosphatidylserine exposure in apoptotic cells. Science 2013, 341:403-406.
-
(2013)
Science
, vol.341
, pp. 403-406
-
-
Suzuki, J.1
Denning, D.P.2
Imanishi, E.3
Horvitz, H.R.4
Nagata, S.5
-
94
-
-
77956095537
-
Mitochondria and cell death: outer membrane permeabilization and beyond
-
Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol. Cell Biol. 2010, 11:621-632.
-
(2010)
Nat. Rev. Mol. Cell Biol.
, vol.11
, pp. 621-632
-
-
Tait, S.W.1
Green, D.R.2
-
95
-
-
33645786318
-
Roles of caspase-and caspase-10 in innate immune responses to double-stranded RNA
-
Takahashi K., Kawai T., Kumar H., Sato S., Yonehara S., Akira S. Roles of caspase-and caspase-10 in innate immune responses to double-stranded RNA. J. Immunol. 2006, 176:4520-4524.
-
(2006)
J. Immunol.
, vol.176
, pp. 4520-4524
-
-
Takahashi, K.1
Kawai, T.2
Kumar, H.3
Sato, S.4
Yonehara, S.5
Akira, S.6
-
97
-
-
0028990125
-
Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
-
Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995, 81:801-809.
-
(1995)
Cell
, vol.81
, pp. 801-809
-
-
Tewari, M.1
Quan, L.T.2
O'Rourke, K.3
Desnoyers, S.4
Zeng, Z.5
Beidler, D.R.6
Poirier, G.G.7
Salvesen, G.S.8
Dixit, V.M.9
-
98
-
-
84880156423
-
An inactivating caspase-11 passenger mutation muddles sepsis research
-
Vanden Berghe T., Goethals A., Demon D., Bogaert P., Mak T.W., Cauwels A., Vandenabeele P. An inactivating caspase-11 passenger mutation muddles sepsis research. Am. J. Respir. Crit. Care Med. 2013, 188:120-121.
-
(2013)
Am. J. Respir. Crit. Care Med.
, vol.188
, pp. 120-121
-
-
Vanden Berghe, T.1
Goethals, A.2
Demon, D.3
Bogaert, P.4
Mak, T.W.5
Cauwels, A.6
Vandenabeele, P.7
-
99
-
-
84894550453
-
Regulated necrosis: The expanding network of non-apoptotic cell death pathways
-
Vanden Berghe T., Linkermann A., Jouan-Lanhouet S., Walczak H., Vandenabeele P. Regulated necrosis: The expanding network of non-apoptotic cell death pathways. Nat. Rev. Mol. Cell Biol. 2014, 15:135-147.
-
(2014)
Nat. Rev. Mol. Cell Biol.
, vol.15
, pp. 135-147
-
-
Vanden Berghe, T.1
Linkermann, A.2
Jouan-Lanhouet, S.3
Walczak, H.4
Vandenabeele, P.5
-
100
-
-
84937694033
-
Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice
-
Vanden Berghe T., Hulpiau P., Martens L., Vandenbroucke R.E., Van Wonterghem E., Perry S.W., Bruggeman I., Divert T., Choi S.M., Vuylsteke M., et al. Passenger Mutations Confound Interpretation of All Genetically Modified Congenic Mice. Immunity 2015, 43:200-209.
-
(2015)
Immunity
, vol.43
, pp. 200-209
-
-
Vanden Berghe, T.1
Hulpiau, P.2
Martens, L.3
Vandenbroucke, R.E.4
Van Wonterghem, E.5
Perry, S.W.6
Bruggeman, I.7
Divert, T.8
Choi, S.M.9
Vuylsteke, M.10
-
101
-
-
84945542875
-
Human caspase-and caspase-regulate the one-step non-canonical inflammasome activation in monocytes
-
Viganò E., Diamond C.E., Spreafico R., Balachander A., Sobota R.M., Mortellaro A. Human caspase-and caspase-regulate the one-step non-canonical inflammasome activation in monocytes. Nat. Commun. 2015, 6:8761.
-
(2015)
Nat. Commun.
, vol.6
, pp. 8761
-
-
Viganò, E.1
Diamond, C.E.2
Spreafico, R.3
Balachander, A.4
Sobota, R.M.5
Mortellaro, A.6
-
102
-
-
84857404572
-
Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-activation
-
Vince J.E., Wong W.W., Gentle I., Lawlor K.E., Allam R., O'Reilly L., Mason K., Gross O., Ma S., Guarda G., et al. Inhibitor of apoptosis proteins limit RIP3 kinase-dependent interleukin-activation. Immunity 2012, 36:215-227.
-
(2012)
Immunity
, vol.36
, pp. 215-227
-
-
Vince, J.E.1
Wong, W.W.2
Gentle, I.3
Lawlor, K.E.4
Allam, R.5
O'Reilly, L.6
Mason, K.7
Gross, O.8
Ma, S.9
Guarda, G.10
-
103
-
-
11144329661
-
Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation
-
Walsh D.S., Borke J.L., Singh B.B., Do N.N., Hsu S.D., Balagon M.V., Abalos R.M. Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation. J. Dermatol. Sci. 2005, 37:61-63.
-
(2005)
J. Dermatol. Sci.
, vol.37
, pp. 61-63
-
-
Walsh, D.S.1
Borke, J.L.2
Singh, B.B.3
Do, N.N.4
Hsu, S.D.5
Balagon, M.V.6
Abalos, R.M.7
-
104
-
-
0032548919
-
Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
-
Wang S., Miura M., Jung Y.K., Zhu H., Li E., Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 1998, 92:501-509.
-
(1998)
Cell
, vol.92
, pp. 501-509
-
-
Wang, S.1
Miura, M.2
Jung, Y.K.3
Zhu, H.4
Li, E.5
Yuan, J.6
-
105
-
-
77956947459
-
Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I
-
Wang P., Arjona A., Zhang Y., Sultana H., Dai J., Yang L., LeBlanc P.M., Doiron K., Saleh M., Fikrig E. Caspase-12 controls West Nile virus infection via the viral RNA receptor RIG-I. Nat. Immunol. 2010, 11:912-919.
-
(2010)
Nat. Immunol.
, vol.11
, pp. 912-919
-
-
Wang, P.1
Arjona, A.2
Zhang, Y.3
Sultana, H.4
Dai, J.5
Yang, L.6
LeBlanc, P.M.7
Doiron, K.8
Saleh, M.9
Fikrig, E.10
-
106
-
-
84919884654
-
Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production
-
White M.J., McArthur K., Metcalf D., Lane R.M., Cambier J.C., Herold M.J., van Delft M.F., Bedoui S., Lessene G., Ritchie M.E., et al. Apoptotic caspases suppress mtDNA-induced STING-mediated type I IFN production. Cell 2014, 159:1549-1562.
-
(2014)
Cell
, vol.159
, pp. 1549-1562
-
-
White, M.J.1
McArthur, K.2
Metcalf, D.3
Lane, R.M.4
Cambier, J.C.5
Herold, M.J.6
van Delft, M.F.7
Bedoui, S.8
Lessene, G.9
Ritchie, M.E.10
-
107
-
-
84947441282
-
Caspase-11 requires the Pannexin-channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock
-
Yang D., He Y., Muñoz-Planillo R., Liu Q., Núñez G. Caspase-11 requires the Pannexin-channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock. Immunity 2015, 43:923-932.
-
(2015)
Immunity
, vol.43
, pp. 923-932
-
-
Yang, D.1
He, Y.2
Muñoz-Planillo, R.3
Liu, Q.4
Núñez, G.5
-
108
-
-
67049158196
-
Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection
-
Yeretssian G., Doiron K., Shao W., Leavitt B.R., Hayden M.R., Nicholson D.W., Saleh M. Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 2009, 106:9016-9020.
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 9016-9020
-
-
Yeretssian, G.1
Doiron, K.2
Shao, W.3
Leavitt, B.R.4
Hayden, M.R.5
Nicholson, D.W.6
Saleh, M.7
-
109
-
-
0032544564
-
Apaf1 is required for mitochondrial pathways of apoptosis and brain development
-
Yoshida H., Kong Y.Y., Yoshida R., Elia A.J., Hakem A., Hakem R., Penninger J.M., Mak T.W. Apaf1 is required for mitochondrial pathways of apoptosis and brain development. Cell 1998, 94:739-750.
-
(1998)
Cell
, vol.94
, pp. 739-750
-
-
Yoshida, H.1
Kong, Y.Y.2
Yoshida, R.3
Elia, A.J.4
Hakem, A.5
Hakem, R.6
Penninger, J.M.7
Mak, T.W.8
-
110
-
-
84941419767
-
Cyclooxygenase-dependent tumor growth through evasion of immunity
-
Zelenay S., van der Veen A.G., Böttcher J.P., Snelgrove K.J., Rogers N., Acton S.E., Chakravarty P., Girotti M.R., Marais R., Quezada S.A., et al. Cyclooxygenase-dependent tumor growth through evasion of immunity. Cell 2015, 162:1257-1270.
-
(2015)
Cell
, vol.162
, pp. 1257-1270
-
-
Zelenay, S.1
van der Veen, A.G.2
Böttcher, J.P.3
Snelgrove, K.J.4
Rogers, N.5
Acton, S.E.6
Chakravarty, P.7
Girotti, M.R.8
Marais, R.9
Quezada, S.A.10
-
111
-
-
84858643750
-
Inflammasomes in carcinogenesis and anticancer immune responses
-
Zitvogel L., Kepp O., Galluzzi L., Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat. Immunol. 2012, 13:343-351.
-
(2012)
Nat. Immunol.
, vol.13
, pp. 343-351
-
-
Zitvogel, L.1
Kepp, O.2
Galluzzi, L.3
Kroemer, G.4
-
112
-
-
84880747672
-
Mechanism of action of conventional and targeted anticancer therapies: Reinstating immunosurveillance
-
Zitvogel L., Galluzzi L., Smyth M.J., Kroemer G. Mechanism of action of conventional and targeted anticancer therapies: Reinstating immunosurveillance. Immunity 2013, 39:74-88.
-
(2013)
Immunity
, vol.39
, pp. 74-88
-
-
Zitvogel, L.1
Galluzzi, L.2
Smyth, M.J.3
Kroemer, G.4
-
113
-
-
84933277745
-
Type I interferons in anticancer immunity
-
Zitvogel L., Galluzzi L., Kepp O., Smyth M.J., Kroemer G. Type I interferons in anticancer immunity. Nat. Rev. Immunol. 2015, 15:405-414.
-
(2015)
Nat. Rev. Immunol.
, vol.15
, pp. 405-414
-
-
Zitvogel, L.1
Galluzzi, L.2
Kepp, O.3
Smyth, M.J.4
Kroemer, G.5
|