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Volumn 44, Issue 2, 2016, Pages 221-231

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

Author keywords

Apoptosome; Damage associated molecular pattern; Inflammasome; Mitochondrial outer membrane permeabilization; Necroptosis; Pyroptosis

Indexed keywords

CASPASE;

EID: 84958614726     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2016.01.020     Document Type: Review
Times cited : (284)

References (113)
  • 2
    • 84906852294 scopus 로고    scopus 로고
    • Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-is required for inflammasome priming
    • Allam R., Lawlor K.E., Yu E.C., Mildenhall A.L., Moujalled D.M., Lewis R.S., Ke F., Mason K.D., White M.J., Stacey K.J., et al. Mitochondrial apoptosis is dispensable for NLRP3 inflammasome activation but non-apoptotic caspase-is required for inflammasome priming. EMBO Rep. 2014, 15:982-990.
    • (2014) EMBO Rep. , vol.15 , pp. 982-990
    • Allam, R.1    Lawlor, K.E.2    Yu, E.C.3    Mildenhall, A.L.4    Moujalled, D.M.5    Lewis, R.S.6    Ke, F.7    Mason, K.D.8    White, M.J.9    Stacey, K.J.10
  • 3
    • 0023663870 scopus 로고
    • A cell that dies during wild-type C. elegans development can function as a neuron in a ced-mutant
    • Avery L., Horvitz H.R. A cell that dies during wild-type C. elegans development can function as a neuron in a ced-mutant. Cell 1987, 51:1071-1078.
    • (1987) Cell , vol.51 , pp. 1071-1078
    • Avery, L.1    Horvitz, H.R.2
  • 7
    • 84896801592 scopus 로고    scopus 로고
    • Extracellular caspase-drives murine inflammatory pain via microglial TNF-α secretion
    • Berta T., Park C.K., Xu Z.Z., Xie R.G., Liu T., Lü N., Liu Y.C., Ji R.R. Extracellular caspase-drives murine inflammatory pain via microglial TNF-α secretion. J. Clin. Invest. 2014, 124:1173-1186.
    • (2014) J. Clin. Invest. , vol.124 , pp. 1173-1186
    • Berta, T.1    Park, C.K.2    Xu, Z.Z.3    Xie, R.G.4    Liu, T.5    Lü, N.6    Liu, Y.C.7    Ji, R.R.8
  • 10
    • 84941652089 scopus 로고    scopus 로고
    • Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage
    • Bronner D.N., Abuaita B.H., Chen X., Fitzgerald K.A., Nuñez G., He Y., Yin X.M., O'Riordan M.X. Endoplasmic Reticulum Stress Activates the Inflammasome via NLRP3- and Caspase-2-Driven Mitochondrial Damage. Immunity 2015, 43:451-462.
    • (2015) Immunity , vol.43 , pp. 451-462
    • Bronner, D.N.1    Abuaita, B.H.2    Chen, X.3    Fitzgerald, K.A.4    Nuñez, G.5    He, Y.6    Yin, X.M.7    O'Riordan, M.X.8
  • 11
    • 84867333450 scopus 로고    scopus 로고
    • Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1
    • Broz P., Ruby T., Belhocine K., Bouley D.M., Kayagaki N., Dixit V.M., Monack D.M. Caspase-11 increases susceptibility to Salmonella infection in the absence of caspase-1. Nature 2012, 490:288-291.
    • (2012) Nature , vol.490 , pp. 288-291
    • Broz, P.1    Ruby, T.2    Belhocine, K.3    Bouley, D.M.4    Kayagaki, N.5    Dixit, V.M.6    Monack, D.M.7
  • 13
    • 84920950343 scopus 로고    scopus 로고
    • IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy
    • Cayrol C., Girard J.P. IL-33: An alarmin cytokine with crucial roles in innate immunity, inflammation and allergy. Curr. Opin. Immunol. 2014, 31:31-37.
    • (2014) Curr. Opin. Immunol. , vol.31 , pp. 31-37
    • Cayrol, C.1    Girard, J.P.2
  • 14
    • 84937577488 scopus 로고    scopus 로고
    • Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis
    • Cullen S.P., Kearney C.J., Clancy D.M., Martin S.J. Diverse Activators of the NLRP3 Inflammasome Promote IL-1β Secretion by Triggering Necrosis. Cell Rep. 2015, 11:1535-1548.
    • (2015) Cell Rep. , vol.11 , pp. 1535-1548
    • Cullen, S.P.1    Kearney, C.J.2    Clancy, D.M.3    Martin, S.J.4
  • 15
    • 10644288480 scopus 로고    scopus 로고
    • Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis
    • Daish T.J., Mills K., Kumar S. Drosophila caspase DRONC is required for specific developmental cell death pathways and stress-induced apoptosis. Dev. Cell 2004, 7:909-915.
    • (2004) Dev. Cell , vol.7 , pp. 909-915
    • Daish, T.J.1    Mills, K.2    Kumar, S.3
  • 18
  • 19
    • 1942444411 scopus 로고    scopus 로고
    • Identification of genes involved in apoptosis and dominant follicle development during follicular waves in cattle
    • Evans A.C., Ireland J.L., Winn M.E., Lonergan P., Smith G.W., Coussens P.M., Ireland J.J. Identification of genes involved in apoptosis and dominant follicle development during follicular waves in cattle. Biol. Reprod. 2004, 70:1475-1484.
    • (2004) Biol. Reprod. , vol.70 , pp. 1475-1484
    • Evans, A.C.1    Ireland, J.L.2    Winn, M.E.3    Lonergan, P.4    Smith, G.W.5    Coussens, P.M.6    Ireland, J.J.7
  • 23
    • 77951673268 scopus 로고    scopus 로고
    • TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity
    • Freeman G.J., Casasnovas J.M., Umetsu D.T., DeKruyff R.H. TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity. Immunol. Rev. 2010, 235:172-189.
    • (2010) Immunol. Rev. , vol.235 , pp. 172-189
    • Freeman, G.J.1    Casasnovas, J.M.2    Umetsu, D.T.3    DeKruyff, R.H.4
  • 24
    • 81055125652 scopus 로고    scopus 로고
    • Programmed cell death in animal development and disease
    • Fuchs Y., Steller H. Programmed cell death in animal development and disease. Cell 2011, 147:742-758.
    • (2011) Cell , vol.147 , pp. 742-758
    • Fuchs, Y.1    Steller, H.2
  • 25
    • 84870206960 scopus 로고    scopus 로고
    • Mitochondria: master regulators of danger signalling
    • Galluzzi L., Kepp O., Kroemer G. Mitochondria: master regulators of danger signalling. Nat. Rev. Mol. Cell Biol. 2012, 13:780-788.
    • (2012) Nat. Rev. Mol. Cell Biol. , vol.13 , pp. 780-788
    • Galluzzi, L.1    Kepp, O.2    Kroemer, G.3
  • 33
    • 84883790050 scopus 로고    scopus 로고
    • Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock
    • Hagar J.A., Powell D.A., Aachoui Y., Ernst R.K., Miao E.A. Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock. Science 2013, 341:1250-1253.
    • (2013) Science , vol.341 , pp. 1250-1253
    • Hagar, J.A.1    Powell, D.A.2    Aachoui, Y.3    Ernst, R.K.4    Miao, E.A.5
  • 37
    • 84874263775 scopus 로고    scopus 로고
    • Necroptosis: The release of damage-associated molecular patterns and its physiological relevance
    • Kaczmarek A., Vandenabeele P., Krysko D.V. Necroptosis: The release of damage-associated molecular patterns and its physiological relevance. Immunity 2013, 38:209-223.
    • (2013) Immunity , vol.38 , pp. 209-223
    • Kaczmarek, A.1    Vandenabeele, P.2    Krysko, D.V.3
  • 39
    • 84872764927 scopus 로고    scopus 로고
    • Caspase-blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome
    • Kang T.B., Yang S.H., Toth B., Kovalenko A., Wallach D. Caspase-blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome. Immunity 2013, 38:27-40.
    • (2013) Immunity , vol.38 , pp. 27-40
    • Kang, T.B.1    Yang, S.H.2    Toth, B.3    Kovalenko, A.4    Wallach, D.5
  • 44
    • 84859464225 scopus 로고    scopus 로고
    • An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1
    • Kenneth N.S., Younger J.M., Hughes E.D., Marcotte D., Barker P.A., Saunders T.L., Duckett C.S. An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1. Biochem. J. 2012, 443:355-359.
    • (2012) Biochem. J. , vol.443 , pp. 355-359
    • Kenneth, N.S.1    Younger, J.M.2    Hughes, E.D.3    Marcotte, D.4    Barker, P.A.5    Saunders, T.L.6    Duckett, C.S.7
  • 47
    • 79251585912 scopus 로고    scopus 로고
    • Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-receptor-associated kinase-M
    • Kobayashi H., Nolan A., Naveed B., Hoshino Y., Segal L.N., Fujita Y., Rom W.N., Weiden M.D. Neutrophils activate alveolar macrophages by producing caspase-6-mediated cleavage of IL-receptor-associated kinase-M. J. Immunol. 2011, 186:403-410.
    • (2011) J. Immunol. , vol.186 , pp. 403-410
    • Kobayashi, H.1    Nolan, A.2    Naveed, B.3    Hoshino, Y.4    Segal, L.N.5    Fujita, Y.6    Rom, W.N.7    Weiden, M.D.8
  • 49
    • 14044251695 scopus 로고    scopus 로고
    • Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution
    • Kroemer G. Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution. Cell Death Differ. 1997, 4:443-456.
    • (1997) Cell Death Differ. , vol.4 , pp. 443-456
    • Kroemer, G.1
  • 54
    • 0027990778 scopus 로고
    • Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-and the mammalian IL-beta-converting enzyme
    • Kumar S., Kinoshita M., Noda M., Copeland N.G., Jenkins N.A. Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-and the mammalian IL-beta-converting enzyme. Genes Dev. 1994, 8:1613-1626.
    • (1994) Genes Dev. , vol.8 , pp. 1613-1626
    • Kumar, S.1    Kinoshita, M.2    Noda, M.3    Copeland, N.G.4    Jenkins, N.A.5
  • 57
    • 84901310586 scopus 로고    scopus 로고
    • Mechanisms and functions of inflammasomes
    • Lamkanfi M., Dixit V.M. Mechanisms and functions of inflammasomes. Cell 2014, 157:1013-1022.
    • (2014) Cell , vol.157 , pp. 1013-1022
    • Lamkanfi, M.1    Dixit, V.M.2
  • 60
    • 63649143438 scopus 로고    scopus 로고
    • Dynamic expression of epidermal caspase 8 simulates a wound healing response
    • Lee P., Lee D.J., Chan C., Chen S.W., Ch'en I., Jamora C. Dynamic expression of epidermal caspase 8 simulates a wound healing response. Nature 2009, 458:519-523.
    • (2009) Nature , vol.458 , pp. 519-523
    • Lee, P.1    Lee, D.J.2    Chan, C.3    Chen, S.W.4    Ch'en, I.5    Jamora, C.6
  • 61
    • 84865164564 scopus 로고    scopus 로고
    • Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection
    • Li X., He Y. Caspase-2-dependent dendritic cell death, maturation, and priming of T cells in response to Brucella abortus infection. PLoS ONE 2012, 7:e43512.
    • (2012) PLoS ONE , vol.7 , pp. e43512
    • Li, X.1    He, Y.2
  • 62
    • 0028984948 scopus 로고
    • Mice deficient in IL-beta-converting enzyme are defective in production of mature IL-beta and resistant to endotoxic shock
    • Li P., Allen H., Banerjee S., Franklin S., Herzog L., Johnston C., McDowell J., Paskind M., Rodman L., Salfeld J., et al. Mice deficient in IL-beta-converting enzyme are defective in production of mature IL-beta and resistant to endotoxic shock. Cell 1995, 80:401-411.
    • (1995) Cell , vol.80 , pp. 401-411
    • Li, P.1    Allen, H.2    Banerjee, S.3    Franklin, S.4    Herzog, L.5    Johnston, C.6    McDowell, J.7    Paskind, M.8    Rodman, L.9    Salfeld, J.10
  • 63
    • 0030715323 scopus 로고    scopus 로고
    • Cytochrome c and dATP-dependent formation of Apaf-1/caspase-complex initiates an apoptotic protease cascade
    • Li P., Nijhawan D., Budihardjo I., Srinivasula S.M., Ahmad M., Alnemri E.S., Wang X. Cytochrome c and dATP-dependent formation of Apaf-1/caspase-complex initiates an apoptotic protease cascade. Cell 1997, 91:479-489.
    • (1997) Cell , vol.91 , pp. 479-489
    • Li, P.1    Nijhawan, D.2    Budihardjo, I.3    Srinivasula, S.M.4    Ahmad, M.5    Alnemri, E.S.6    Wang, X.7
  • 64
    • 0345374586 scopus 로고    scopus 로고
    • Phosphatidylserine receptor is required for clearance of apoptotic cells
    • Li M.O., Sarkisian M.R., Mehal W.Z., Rakic P., Flavell R.A. Phosphatidylserine receptor is required for clearance of apoptotic cells. Science 2003, 302:1560-1563.
    • (2003) Science , vol.302 , pp. 1560-1563
    • Li, M.O.1    Sarkisian, M.R.2    Mehal, W.Z.3    Rakic, P.4    Flavell, R.A.5
  • 65
    • 77949847250 scopus 로고    scopus 로고
    • Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration
    • Li F., Huang Q., Chen J., Peng Y., Roop D.R., Bedford J.S., Li C.Y. Apoptotic cells activate the "phoenix rising" pathway to promote wound healing and tissue regeneration. Sci. Signal. 2010, 3:ra13.
    • (2010) Sci. Signal. , vol.3 , pp. ra13
    • Li, F.1    Huang, Q.2    Chen, J.3    Peng, Y.4    Roop, D.R.5    Bedford, J.S.6    Li, C.Y.7
  • 69
    • 84947416929 scopus 로고    scopus 로고
    • Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium
    • Maltez V.I., Tubbs A.L., Cook K.D., Aachoui Y., Falcone E.L., Holland S.M., Whitmire J.K., Miao E.A. Inflammasomes coordinate pyroptosis and natural killer cell cytotoxicity to clear infection by a ubiquitous environmental bacterium. Immunity 2015, 43:987-997.
    • (2015) Immunity , vol.43 , pp. 987-997
    • Maltez, V.I.1    Tubbs, A.L.2    Cook, K.D.3    Aachoui, Y.4    Falcone, E.L.5    Holland, S.M.6    Whitmire, J.K.7    Miao, E.A.8
  • 70
    • 84861435630 scopus 로고    scopus 로고
    • A perspective on mammalian caspases as positive and negative regulators of inflammation
    • Martin S.J., Henry C.M., Cullen S.P. A perspective on mammalian caspases as positive and negative regulators of inflammation. Mol. Cell 2012, 46:387-397.
    • (2012) Mol. Cell , vol.46 , pp. 387-397
    • Martin, S.J.1    Henry, C.M.2    Cullen, S.P.3
  • 71
    • 0036671894 scopus 로고    scopus 로고
    • The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta
    • Martinon F., Burns K., Tschopp J. The inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol. Cell 2002, 10:417-426.
    • (2002) Mol. Cell , vol.10 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 73
    • 84922570928 scopus 로고    scopus 로고
    • A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing
    • Moriwaki K., Bertin J., Gough P.J., Chan F.K. A RIPK3-caspase 8 complex mediates atypical pro-IL-1β processing. J. Immunol. 2015, 194:1938-1944.
    • (2015) J. Immunol. , vol.194 , pp. 1938-1944
    • Moriwaki, K.1    Bertin, J.2    Gough, P.J.3    Chan, F.K.4
  • 86
    • 84901849205 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure
    • Segawa K., Kurata S., Yanagihashi Y., Brummelkamp T.R., Matsuda F., Nagata S. Caspase-mediated cleavage of phospholipid flippase for apoptotic phosphatidylserine exposure. Science 2014, 344:1164-1168.
    • (2014) Science , vol.344 , pp. 1164-1168
    • Segawa, K.1    Kurata, S.2    Yanagihashi, Y.3    Brummelkamp, T.R.4    Matsuda, F.5    Nagata, S.6
  • 88
    • 84906571225 scopus 로고    scopus 로고
    • Inflammatory caspases are innate immune receptors for intracellular LPS
    • Shi J., Zhao Y., Wang Y., Gao W., Ding J., Li P., Hu L., Shao F. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014, 514:187-192.
    • (2014) Nature , vol.514 , pp. 187-192
    • Shi, J.1    Zhao, Y.2    Wang, Y.3    Gao, W.4    Ding, J.5    Li, P.6    Hu, L.7    Shao, F.8
  • 93
    • 84880758440 scopus 로고    scopus 로고
    • Xk-related protein 8 and CED-promote phosphatidylserine exposure in apoptotic cells
    • Suzuki J., Denning D.P., Imanishi E., Horvitz H.R., Nagata S. Xk-related protein 8 and CED-promote phosphatidylserine exposure in apoptotic cells. Science 2013, 341:403-406.
    • (2013) Science , vol.341 , pp. 403-406
    • Suzuki, J.1    Denning, D.P.2    Imanishi, E.3    Horvitz, H.R.4    Nagata, S.5
  • 94
    • 77956095537 scopus 로고    scopus 로고
    • Mitochondria and cell death: outer membrane permeabilization and beyond
    • Tait S.W., Green D.R. Mitochondria and cell death: outer membrane permeabilization and beyond. Nat. Rev. Mol. Cell Biol. 2010, 11:621-632.
    • (2010) Nat. Rev. Mol. Cell Biol. , vol.11 , pp. 621-632
    • Tait, S.W.1    Green, D.R.2
  • 95
    • 33645786318 scopus 로고    scopus 로고
    • Roles of caspase-and caspase-10 in innate immune responses to double-stranded RNA
    • Takahashi K., Kawai T., Kumar H., Sato S., Yonehara S., Akira S. Roles of caspase-and caspase-10 in innate immune responses to double-stranded RNA. J. Immunol. 2006, 176:4520-4524.
    • (2006) J. Immunol. , vol.176 , pp. 4520-4524
    • Takahashi, K.1    Kawai, T.2    Kumar, H.3    Sato, S.4    Yonehara, S.5    Akira, S.6
  • 97
    • 0028990125 scopus 로고
    • Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase
    • Tewari M., Quan L.T., O'Rourke K., Desnoyers S., Zeng Z., Beidler D.R., Poirier G.G., Salvesen G.S., Dixit V.M. Yama/CPP32 beta, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 1995, 81:801-809.
    • (1995) Cell , vol.81 , pp. 801-809
    • Tewari, M.1    Quan, L.T.2    O'Rourke, K.3    Desnoyers, S.4    Zeng, Z.5    Beidler, D.R.6    Poirier, G.G.7    Salvesen, G.S.8    Dixit, V.M.9
  • 103
    • 11144329661 scopus 로고    scopus 로고
    • Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation
    • Walsh D.S., Borke J.L., Singh B.B., Do N.N., Hsu S.D., Balagon M.V., Abalos R.M. Psoriasis is characterized by altered epidermal expression of caspase 14, a novel regulator of keratinocyte terminal differentiation and barrier formation. J. Dermatol. Sci. 2005, 37:61-63.
    • (2005) J. Dermatol. Sci. , vol.37 , pp. 61-63
    • Walsh, D.S.1    Borke, J.L.2    Singh, B.B.3    Do, N.N.4    Hsu, S.D.5    Balagon, M.V.6    Abalos, R.M.7
  • 104
    • 0032548919 scopus 로고    scopus 로고
    • Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE
    • Wang S., Miura M., Jung Y.K., Zhu H., Li E., Yuan J. Murine caspase-11, an ICE-interacting protease, is essential for the activation of ICE. Cell 1998, 92:501-509.
    • (1998) Cell , vol.92 , pp. 501-509
    • Wang, S.1    Miura, M.2    Jung, Y.K.3    Zhu, H.4    Li, E.5    Yuan, J.6
  • 107
    • 84947441282 scopus 로고    scopus 로고
    • Caspase-11 requires the Pannexin-channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock
    • Yang D., He Y., Muñoz-Planillo R., Liu Q., Núñez G. Caspase-11 requires the Pannexin-channel and the purinergic P2X7 pore to mediate pyroptosis and endotoxic shock. Immunity 2015, 43:923-932.
    • (2015) Immunity , vol.43 , pp. 923-932
    • Yang, D.1    He, Y.2    Muñoz-Planillo, R.3    Liu, Q.4    Núñez, G.5
  • 108
    • 67049158196 scopus 로고    scopus 로고
    • Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection
    • Yeretssian G., Doiron K., Shao W., Leavitt B.R., Hayden M.R., Nicholson D.W., Saleh M. Gender differences in expression of the human caspase-12 long variant determines susceptibility to Listeria monocytogenes infection. Proc. Natl. Acad. Sci. USA 2009, 106:9016-9020.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 9016-9020
    • Yeretssian, G.1    Doiron, K.2    Shao, W.3    Leavitt, B.R.4    Hayden, M.R.5    Nicholson, D.W.6    Saleh, M.7
  • 111
    • 84858643750 scopus 로고    scopus 로고
    • Inflammasomes in carcinogenesis and anticancer immune responses
    • Zitvogel L., Kepp O., Galluzzi L., Kroemer G. Inflammasomes in carcinogenesis and anticancer immune responses. Nat. Immunol. 2012, 13:343-351.
    • (2012) Nat. Immunol. , vol.13 , pp. 343-351
    • Zitvogel, L.1    Kepp, O.2    Galluzzi, L.3    Kroemer, G.4
  • 112
    • 84880747672 scopus 로고    scopus 로고
    • Mechanism of action of conventional and targeted anticancer therapies: Reinstating immunosurveillance
    • Zitvogel L., Galluzzi L., Smyth M.J., Kroemer G. Mechanism of action of conventional and targeted anticancer therapies: Reinstating immunosurveillance. Immunity 2013, 39:74-88.
    • (2013) Immunity , vol.39 , pp. 74-88
    • Zitvogel, L.1    Galluzzi, L.2    Smyth, M.J.3    Kroemer, G.4


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