-
1
-
-
0035204919
-
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
-
McIntire JJ, et al. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2001 2 : 1109 1116.
-
(2001)
Nat Immunol
, vol.2
, pp. 1109-1116
-
-
McIntire, J.J.1
-
2
-
-
1442308176
-
TIM-1, a novel allergy and asthma susceptibility gene
-
McIntire JJ, Umetsu DT, DeKruyff RH. TIM-1, a novel allergy and asthma susceptibility gene. Springer Semin Immunopathol 2004 25 : 335 348. (Pubitemid 38285227)
-
(2004)
SPRINGER SEMINARS IN IMMUNOPATHOLOGY
, vol.25
, Issue.3-4
, pp. 335-348
-
-
McIntire, J.J.1
Umetsu, D.T.2
DeKruyff, R.H.3
-
4
-
-
52949098040
-
TIM-1 and TIM-3 proteins in immune regulation
-
Su EW, Lin JY, Kane LP. TIM-1 and TIM-3 proteins in immune regulation. Cytokine 2008 44 : 9 13.
-
(2008)
Cytokine
, vol.44
, pp. 9-13
-
-
Su, E.W.1
Lin, J.Y.2
Kane, L.P.3
-
5
-
-
0028230946
-
Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin e concentrations
-
Marsh DG, et al. Linkage analysis of IL4 and other chromosome 5q31.1 markers and total serum immunoglobulin E concentrations. Science 1994 264 : 1152 1156.
-
(1994)
Science
, vol.264
, pp. 1152-1156
-
-
Marsh, D.G.1
-
6
-
-
0033737679
-
Mapping and identification of autoimmunity genes
-
Encinas JA, Kuchroo VK. Mapping and identification of autoimmunity genes. Curr Opin Immunol 2000 12 : 691 697.
-
(2000)
Curr Opin Immunol
, vol.12
, pp. 691-697
-
-
Encinas, J.A.1
Kuchroo, V.K.2
-
7
-
-
0038143288
-
The TIM gene family: Emerging roles in immunity and disease
-
DOI 10.1038/nri1111
-
Kuchroo V, Umetsu D, DeKruyff R, Freeman G. The TIM gene family: emerging roles in immunity and disease. Nature Rev Immunol 2003 3 : 454 462. (Pubitemid 37339185)
-
(2003)
Nature Reviews Immunology
, vol.3
, Issue.6
, pp. 454-462
-
-
Kuchroo, V.K.1
Umetsu, D.T.2
DeKruyff, R.H.3
Freeman, G.J.4
-
8
-
-
37049039277
-
Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds
-
DOI 10.1016/j.immuni.2007.11.008, PII S1074761307005420
-
Santiago C, et al. Structures of T cell immunoglobulin mucin protein 4 show a metal-ion-dependent ligand binding site where phosphatidylserine binds. Immunity 2007 27 : 941 951. (Pubitemid 50013979)
-
(2007)
Immunity
, vol.27
, Issue.6
, pp. 941-951
-
-
Santiago, C.1
Ballesteros, A.2
Martinez-Munoz, L.3
Mellado, M.4
Kaplan, G.G.5
Freeman, G.J.6
Casasnovas, J.M.7
-
9
-
-
77949900365
-
T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells
-
DeKruyff RH, et al. T cell/transmembrane, Ig, and mucin-3 allelic variants differentially recognize phosphatidylserine and mediate phagocytosis of apoptotic cells. J Immunol 2010 184 : 1918 1930.
-
(2010)
J Immunol
, vol.184
, pp. 1918-1930
-
-
Dekruyff, R.H.1
-
10
-
-
0026508561
-
Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages
-
Fadok VA, Voelker DR, Campbell PA, Cohen JJ, Bratton DL, Henson PM. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol 1992 148 : 2207 2216.
-
(1992)
J Immunol
, vol.148
, pp. 2207-2216
-
-
Fadok, V.A.1
Voelker, D.R.2
Campbell, P.A.3
Cohen, J.J.4
Bratton, D.L.5
Henson, P.M.6
-
11
-
-
0028820202
-
Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes
-
Verhoven B, Schlegel RA, Williamson P. Mechanisms of phosphatidylserine exposure, a phagocyte recognition signal, on apoptotic T lymphocytes. J Exp Med 1995 182 : 1597 1601.
-
(1995)
J Exp Med
, vol.182
, pp. 1597-1601
-
-
Verhoven, B.1
Schlegel, R.A.2
Williamson, P.3
-
12
-
-
0036884424
-
A blast from the past: Clearance of apoptotic cells regulates immune responses
-
DOI 10.1038/nri957
-
Savill J, Dransfield I, Gregory C, Haslett C. A blast from the past: clearance of apoptotic cells regulates immune responses. Nat Rev Immunol 2002 2 : 965 975. (Pubitemid 37323217)
-
(2002)
Nature Reviews Immunology
, vol.2
, Issue.12
, pp. 965-975
-
-
Savill, J.1
Dransfield, I.2
Gregory, C.3
Haslett, C.4
-
13
-
-
0142259151
-
Hepatitis A virus link to atopic disease
-
DOI 10.1038/425576a
-
McIntire J, et al. Immunology: hepatitis A virus link to atopic disease. Nature 2003 425 : 576. (Pubitemid 37280135)
-
(2003)
Nature
, vol.425
, Issue.6958
, pp. 576
-
-
McIntire, J.J.1
Umetsu, S.E.2
Macaubas, C.3
Hoyte, E.G.4
Cinnioglu, C.5
Cavalli-Sforza, L.L.6
Barsh, G.S.7
Hallmayer, J.F.8
Underhill, P.A.9
Risch, N.J.10
Freeman, G.J.11
DeKruyff, R.H.12
Umetsu, D.T.13
-
14
-
-
18244365585
-
TIM-1 induces T cell activation and inhibits the development of peripheral tolerance
-
Umetsu SE, et al. TIM-1 induces T cell activation and inhibits the development of peripheral tolerance. Nat Immunol 2005 6 : 447 454.
-
(2005)
Nat Immunol
, vol.6
, pp. 447-454
-
-
Umetsu, S.E.1
-
15
-
-
30044434075
-
The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity
-
DOI 10.1038/ni1271, PII N1271
-
Zhu C, et al. The Tim-3 ligand galectin-9 negatively regulates T helper type 1 immunity. Nat Immunol 2005 6 : 1245 1252. (Pubitemid 43045636)
-
(2005)
Nature Immunology
, vol.6
, Issue.12
, pp. 1245-1252
-
-
Zhu, C.1
Anderson, A.C.2
Schubart, A.3
Xiong, H.4
Imitola, J.5
Khoury, S.J.6
Zheng, X.X.7
Strom, T.B.8
Kuchroo, V.K.9
-
16
-
-
65549168745
-
Tim-3 mediates phagocytosis of apoptotic cells and the cross-presentation
-
Nakayama M, et al. Tim-3 mediates phagocytosis of apoptotic cells and the cross-presentation. Blood 2009 113 : 3821 3830.
-
(2009)
Blood
, vol.113
, pp. 3821-3830
-
-
Nakayama, M.1
-
17
-
-
37049004424
-
TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells
-
DOI 10.1016/j.immuni.2007.11.011, PII S1074761307005468
-
Kobayashi N, et al. TIM-1 and TIM-4 glycoproteins bind phosphatidylserine and mediate uptake of apoptotic cells. Immunity 2007 27 : 927 940. (Pubitemid 50014866)
-
(2007)
Immunity
, vol.27
, Issue.6
, pp. 927-940
-
-
Kobayashi, N.1
Karisola, P.2
Pena-Cruz, V.3
Dorfman, D.M.4
Jinushi, M.5
Umetsu, S.E.6
Butte, M.J.7
Nagumo, H.8
Chernova, I.9
Zhu, B.10
Sharpe, A.H.11
Ito, S.12
Dranoff, G.13
Kaplan, G.G.14
Casasnovas, J.M.15
Umetsu, D.T.16
DeKruyff, R.H.17
Freeman, G.J.18
-
18
-
-
36248944555
-
Identification of Tim4 as a phosphatidylserine receptor
-
DOI 10.1038/nature06307, PII NATURE06307
-
Miyanishi M, Tada K, Koike M, Uchiyama Y, Kitamura T, Nagata S. Identification of Tim4 as a phosphatidylserine receptor. Nature 2007 450 : 435 439. (Pubitemid 350126753)
-
(2007)
Nature
, vol.450
, Issue.7168
, pp. 435-439
-
-
Miyanishi, M.1
Tada, K.2
Koike, M.3
Uchiyama, Y.4
Kitamura, T.5
Nagata, S.6
-
19
-
-
33947190606
-
T Cell Immunoglobulin Mucin-3 Crystal Structure Reveals a Galectin-9-Independent Ligand-Binding Surface
-
DOI 10.1016/j.immuni.2007.01.016, PII S1074761307001781
-
Cao E, et al. T cell immunoglobulin mucin-3 crystal structure reveals a galectin-9-independent ligand-binding surface. Immunity 2007 26 : 311 321. (Pubitemid 46413908)
-
(2007)
Immunity
, vol.26
, Issue.3
, pp. 311-321
-
-
Cao, E.1
Zang, X.2
Ramagopal, U.A.3
Mukhopadhaya, A.4
Fedorov, A.5
Fedorov, E.6
Zencheck, W.D.7
Lary, J.W.8
Cole, J.L.9
Deng, H.10
Xiao, H.11
DiLorenzo, T.P.12
Allison, J.P.13
Nathenson, S.G.14
Almo, S.C.15
-
20
-
-
33947113954
-
Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family
-
DOI 10.1016/j.immuni.2007.01.014, PII S1074761307001756
-
Santiago C, Ballesteros A, Tami C, Martinez-Munoz L, Kaplan GG, Casasnovas JM. Structures of T Cell immunoglobulin mucin receptors 1 and 2 reveal mechanisms for regulation of immune responses by the TIM receptor family. Immunity 2007 26 : 299 310. (Pubitemid 46413905)
-
(2007)
Immunity
, vol.26
, Issue.3
, pp. 299-310
-
-
Santiago, C.1
Ballesteros, A.2
Tami, C.3
Martinez-Munoz, L.4
Kaplan, G.G.5
Casasnovas, J.M.6
-
21
-
-
17944374159
-
X-ray structure of junctional adhesion molecule: Structural basis for homophilic adhesion via a novel dimerization motif
-
DOI 10.1093/emboj/20.16.4391
-
Kostrewa D, et al. X-ray structure of junctional adhesion molecule: structural basis for homophilic adhesion via a novel dimerization motif. EMBO J 2001 20 : 4391 4398. (Pubitemid 32772033)
-
(2001)
EMBO Journal
, vol.20
, Issue.16
, pp. 4391-4398
-
-
Kostrewa, D.1
Brockhaus, M.2
D'Arcy, A.3
Dale, G.E.4
Nelboeck, P.5
Schmid, G.6
Mueller, F.7
Bazzoni, G.8
Dejana, E.9
Bartfai, T.10
Winkler, F.K.11
Hennig, M.12
-
22
-
-
0034435587
-
Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution
-
DOI 10.1016/S0969-2126(00)00528-1, PII S0969212600005281
-
van Raaij MJ, Chouin E, van der Zandt H, Bergelson JM, Cusack S. Dimeric structure of the coxsackievirus and adenovirus receptor D1 domain at 1.7 A resolution. Structure 2000 8 : 1147 1155. (Pubitemid 32667480)
-
(2000)
Structure
, vol.8
, Issue.11
, pp. 1147-1155
-
-
Van Raaij, M.J.1
Chouin, E.2
Van Der Zandt, H.3
Bergelson, J.M.4
Cusack, S.5
-
23
-
-
0033037036
-
Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors
-
Wang JH, et al. Structure of a heterophilic adhesion complex between the human CD2 and CD58 (LFA-3) counterreceptors. Cell 1999 97 : 791 803.
-
(1999)
Cell
, vol.97
, pp. 791-803
-
-
Wang, J.H.1
-
24
-
-
0026488252
-
Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2
-
Jones EY, Davis SJ, Williams AF, Harlos K, Stuart DI. Crystal structure at 2.8 A resolution of a soluble form of the cell adhesion molecule CD2. Nature 1992 360 : 232 239.
-
(1992)
Nature
, vol.360
, pp. 232-239
-
-
Jones, E.Y.1
Davis, S.J.2
Williams, A.F.3
Harlos, K.4
Stuart, D.I.5
-
25
-
-
0346747382
-
Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels
-
Ahmadi KR, et al. Novel association suggests multiple independent QTLs within chromosome 5q21-33 region control variation in total humans IgE levels. Genes Immunol 2003 4 : 289 297.
-
(2003)
Genes Immunol
, vol.4
, pp. 289-297
-
-
Ahmadi, K.R.1
-
26
-
-
0029775055
-
Identification of a surface glycoprotein on African green monkey kidney cells as a receptor for hepatitis A virus
-
Kaplan G, Totsuka A, Thompson P, Akatsuka T, Moritsugu Y, Feinstone SM. Identification of a surface glycoprotein on African green monkey kidney cells as a receptor for hepatitis A virus. EMBO J 1996 15 : 4282 4296. (Pubitemid 26278711)
-
(1996)
EMBO Journal
, vol.15
, Issue.16
, pp. 4282-4296
-
-
Kaplan, G.1
Totsuka, A.2
Thompson, P.3
Akatsuka, T.4
Moritsugu, Y.5
Feinstone, S.M.6
-
27
-
-
0031903498
-
The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor
-
Feigelstock D, Thompson P, Mattoo P, Zhang Y, Kaplan GG. The human homolog of HAVcr-1 codes for a hepatitis A virus cellular receptor. J Virol 1998 72 : 6621 6628. (Pubitemid 28323979)
-
(1998)
Journal of Virology
, vol.72
, Issue.8
, pp. 6621-6628
-
-
Feigelstock, D.1
Thompson, P.2
Mattoo, P.3
Zhang, Y.4
Kaplan, G.G.5
-
28
-
-
0030967169
-
Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus
-
Matricardi PM, et al. Cross sectional retrospective study of prevalence of atopy among Italian military students with antibodies against hepatitis A virus. BMJ 1997 314 : 999 1003. (Pubitemid 27149756)
-
(1997)
British Medical Journal
, vol.314
, Issue.7086
, pp. 999-1003
-
-
Matricardi, P.M.1
Rosmini, F.2
Ferrigno, L.3
Nisini, R.4
Rapicetta, M.5
Chionne, P.6
Stroffolini, T.7
Pasquini, P.8
D'Amelio, R.9
-
29
-
-
0036738382
-
Hay fever and asthma in relation to markers of infection in the United States
-
Matricardi PM, Rosmini F, Panetta V, Ferrigno L, Bonini S. Hay fever and asthma in relation to markers of infection in the United States. J Allergy Clin Immunol 2002 110 : 381 387.
-
(2002)
J Allergy Clin Immunol
, vol.110
, pp. 381-387
-
-
Matricardi, P.M.1
Rosmini, F.2
Panetta, V.3
Ferrigno, L.4
Bonini, S.5
-
30
-
-
18144366600
-
Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population
-
DOI 10.1016/j.jaci.2005.01.035
-
Gao PS, et al. Genetic variants of the T-cell immunoglobulin mucin 1 but not the T-cell immunoglobulin mucin 3 gene are associated with asthma in an African American population. J Allergy Clin Immunol 2005 115 : 982 988. (Pubitemid 40616212)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.115
, Issue.5
, pp. 982-988
-
-
Gao, P.-S.1
Mathias, R.A.2
Plunkett, B.3
Togias, A.4
Barnes, K.C.5
Beaty, T.H.6
Huang, S.-K.7
-
31
-
-
77951673963
-
A cluster of five tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of caucasian children
-
Graves PE, et al. A cluster of five tightly linked polymorphisms in the IL-13 gene is associated with total serum IgE levels in three populations of caucasian children. Am J Resp Crit Care Med 2000 161 : A930.
-
(2000)
Am J Resp Crit Care Med
, vol.161
, pp. 930
-
-
Graves, P.E.1
-
32
-
-
0344413475
-
The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population
-
DOI 10.1016/j.bbrc.2003.10.125
-
Chae S, Song J, Lee Y, Kim J, Chung H. The association of the exon 4 variations of Tim-1 gene with allergic diseases in a Korean population. Biochem Biophys Res Commun 2003 12 : 346 350. (Pubitemid 37445178)
-
(2003)
Biochemical and Biophysical Research Communications
, vol.312
, Issue.2
, pp. 346-350
-
-
Chae, S.-C.1
Song, J.-H.2
Lee, Y.-C.3
Kim, J.-W.4
Chung, H.-T.5
-
33
-
-
65249180125
-
Association analysis of TIM-1 -232G > A and 5383-5397 insertion/deletion polymorphisms with childhood asthma and total serum immunoglobulin e levels in middle China
-
Wu Q, Hu L, Cai P, Li Y, Chen F, Kong L. Association analysis of TIM-1 -232G > A and 5383-5397 insertion/deletion polymorphisms with childhood asthma and total serum immunoglobulin E levels in middle China. J Investig Allergol Clin Immunol 2009 19 : 146 153.
-
(2009)
J Investig Allergol Clin Immunol
, vol.19
, pp. 146-153
-
-
Wu, Q.1
Hu, L.2
Cai, P.3
Li, Y.4
Chen, F.5
Kong, L.6
-
34
-
-
33751216133
-
Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis
-
DOI 10.1159/000095459
-
Page NS, Jones G, Stewart GJ. Genetic association studies between the T cell immunoglobulin mucin (TIM) gene locus and childhood atopic dermatitis. Int Arch Allergy Immunol 2006 141 : 331 336. (Pubitemid 44783903)
-
(2006)
International Archives of Allergy and Immunology
, vol.141
, Issue.4
, pp. 331-336
-
-
Page, N.S.1
Jones, G.2
Stewart, G.J.3
-
35
-
-
0242328177
-
Insertion/deletion coding polymorphisms in hHAVcr-1 are not associated with atopic asthma in the Japanese population
-
DOI 10.1038/sj.gene.6363935
-
Noguchi E, Nakayama J, Kamioka M, Ichikawa K, Shibasaki M, Arinami T. Insertion/deletion coding polymorphisms in hHAVcr-1 are not associated with atopic asthma in the Japanese population. Genes Immun 2003 4 : 170 173. (Pubitemid 38967593)
-
(2003)
Genes and Immunity
, vol.4
, Issue.2
, pp. 170-173
-
-
Noguchi, E.1
Nakayama, J.2
Kamioka, M.3
Ichikawa, K.4
Shibasaki, M.5
Arinami, T.6
-
36
-
-
33751054698
-
Absence of association between two insertion/deletion coding genetic polymorphisms of TIM-1 gene and asthma in Chinese Han population
-
Li JS, et al. Absence of association between two insertion/deletion coding genetic polymorphisms of TIM-1 gene and asthma in Chinese Han population. Int J Immunogenet 2006 33 : 417 422.
-
(2006)
Int J Immunogenet
, vol.33
, pp. 417-422
-
-
Li, J.S.1
-
37
-
-
24644514025
-
Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain - IL-2-inducible T-cell kinase gene cluster in chromosome 5q33
-
DOI 10.1016/j.jaci.2005.05.004, PII S0091674905012856
-
Graves PE, Siroux V, Guerra S, Klimecki WT, Martinez FD. Association of atopy and eczema with polymorphisms in T-cell immunoglobulin domain and mucin domain-IL-2-inducible T-cell kinase gene cluster in chromosome 5 q 33. J Allergy Clin Immunol 2005 116 : 650 656. (Pubitemid 41267142)
-
(2005)
Journal of Allergy and Clinical Immunology
, vol.116
, Issue.3
, pp. 650-656
-
-
Graves, P.E.1
Siroux, V.2
Guerra, S.3
Klimecki, W.T.4
Martinez, F.D.5
-
38
-
-
35348887851
-
A functional polymorphism in the TIM-1 gene is associated with asthma in a Chinese Han population
-
DOI 10.1159/000103992
-
Liu Q, et al. A functional polymorphism in the TIM-1 gene is associated with asthma in a Chinese Han population. Int Arch Allergy Immunol 2007 144 : 197 202. (Pubitemid 47587605)
-
(2007)
International Archives of Allergy and Immunology
, vol.144
, Issue.3
, pp. 197-202
-
-
Liu, Q.1
Shang, L.2
Li, J.3
Wang, P.4
Li, H.5
Wei, C.6
Gong, Y.7
-
39
-
-
32644436269
-
Study on relationship between polymorphism sites of TIM-3 and allergic asthma in a population of adult Hans from Hubei province of China
-
Zhang CC, Wu JM, Cui TP, Wang P, Pan SX. [Study on relationship between polymorphism sites of TIM-3 and allergic asthma in a population of adult Hans from Hubei province of China]. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 2006 23 : 74 77. (Pubitemid 43241939)
-
(2006)
Chinese Journal of Medical Genetics
, vol.23
, Issue.1
, pp. 74-77
-
-
Zhang, C.-C.1
Wu, J.-M.2
Cui, T.-P.3
Wang, P.4
Pan, S.-X.5
-
40
-
-
1342324084
-
The exon 4 variations of Tim-1 gene are associated with rheumatoid arthritis in a Korean population
-
DOI 10.1016/j.bbrc.2004.01.154
-
Chae SC, Song JH, Shim SC, Yoon KS, Chung HT. The exon 4 variations of Tim-1 gene are associated with rheumatoid arthritis in a Korean population. Biochem Biophys Res Commun 2004 315 : 971 975. (Pubitemid 38249398)
-
(2004)
Biochemical and Biophysical Research Communications
, vol.315
, Issue.4
, pp. 971-975
-
-
Chae, S.-C.1
Song, J.-H.2
Shim, S.-C.3
Yoon, K.-S.4
Chung, H.-T.5
-
41
-
-
12944302092
-
The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population
-
DOI 10.1007/s00251-004-0743-5
-
Chae SC, Park YR, Song JH, Shim SC, Yoon KS, Chung HT. The polymorphisms of Tim-1 promoter region are associated with rheumatoid arthritis in a Korean population. Immunogenetics 2005 56 : 696 701. (Pubitemid 40174964)
-
(2005)
Immunogenetics
, vol.56
, Issue.10
, pp. 696-701
-
-
Chae, S.-C.1
Park, Y.-R.2
Song, J.-H.3
Shim, S.-C.4
Yoon, K.-S.5
Chung, H.-T.6
-
42
-
-
2442704124
-
T cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis
-
Khademi M, et al. T Cell Ig- and mucin-domain-containing molecule-3 (TIM-3) and TIM-1 molecules are differentially expressed on human Th1 and Th2 cells and in cerebrospinal fluid-derived mononuclear cells in multiple sclerosis. J Immunol 2004 172 : 7169 7176. (Pubitemid 38669161)
-
(2004)
Journal of Immunology
, vol.172
, Issue.11
, pp. 7169-7176
-
-
Khademi, M.1
Illes, Z.2
Gielen, A.W.3
Marta, M.4
Takazawa, N.5
Baecher-Allan, C.6
Brundin, L.7
Hannerz, J.8
Martin, C.9
Harris, R.A.10
Hafler, D.A.11
Kuchroo, V.K.12
Olsson, T.13
Piehl, F.14
Wallstrom, E.15
-
43
-
-
18244399340
-
TIM-4 is the ligand for TIM-1, and the TIM-1-TIM-4 interaction regulates T cell proliferation
-
DOI 10.1038/ni1185
-
Meyers J, et al. Tim-4 is the ligand for Tim-1, and the Tim-1-Tim-4 interaction regulates T cell expansion. Nature Immunol 2005 6 : 455 464. (Pubitemid 41716758)
-
(2005)
Nature Immunology
, vol.6
, Issue.5
, pp. 455-464
-
-
Meyers, J.H.1
Chakravarti, S.2
Schlesinger, D.3
Illes, Z.4
Waldner, H.5
Umetsu, S.E.6
Kenny, J.7
Zheng, X.X.8
Umetsu, D.T.9
DeKruyff, R.H.10
Strom, T.B.11
Kuchroo, V.K.12
-
44
-
-
34247895422
-
Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17
-
DOI 10.1189/jlb.1006610
-
Nakae S, Iwakura Y, Suto H, Galli SJ. Phenotypic differences between Th1 and Th17 cells and negative regulation of Th1 cell differentiation by IL-17. J Leukoc Biol 2007 81 : 1258 1268. (Pubitemid 46702045)
-
(2007)
Journal of Leukocyte Biology
, vol.81
, Issue.5
, pp. 1258-1268
-
-
Nakae, S.1
Iwakura, Y.2
Suto, H.3
Galli, S.J.4
-
45
-
-
34948848135
-
TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells
-
DOI 10.1182/blood-2006-11-058800
-
Nakae S, et al. TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells. Blood 2007 110 : 2565 2568. (Pubitemid 47523180)
-
(2007)
Blood
, vol.110
, Issue.7
, pp. 2565-2568
-
-
Nakae, S.1
Iikura, M.2
Suto, H.3
Akiba, H.4
Umetsu, D.T.5
DeKruyff, R.H.6
Saito, H.7
Galli, S.J.8
-
46
-
-
33846923122
-
Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses
-
Sizing ID, et al. Epitope-dependent effect of anti-murine TIM-1 monoclonal antibodies on T cell activity and lung immune responses. J Immunol 2007 178 : 2249 2261.
-
(2007)
J Immunol
, vol.178
, pp. 2249-2261
-
-
Sizing, I.D.1
-
47
-
-
0032512724
-
Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury
-
DOI 10.1074/jbc.273.7.4135
-
Ichimura T, et al. Kidney injury molecule-1 (KIM-1), a putative epithelial cell adhesion molecule containing a novel immunoglobulin domain, is up-regulated in renal cells after injury. J Biol Chem 1998 273 : 4135 4142. (Pubitemid 28103282)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.7
, pp. 4135-4142
-
-
Ichimura, T.1
Bonventre, J.V.2
Bailly, V.3
Wei, H.4
Hession, C.A.5
Cate, R.L.6
Sanicola, M.7
-
48
-
-
43049125804
-
Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells
-
DOI 10.1172/JCI34487
-
Ichimura T, Asseldonk EJ, Humphreys BD, Gunaratnam L, Duffield JS, Bonventre JV. Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells. J Clin Invest 2008 118 : 1657 1668. (Pubitemid 351632370)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.5
, pp. 1657-1668
-
-
Ichimura, T.1
Asseldonk, E.J.P.V.2
Humphreys, B.D.3
Gunaratnam, L.4
Duffield, J.S.5
Bonventre, J.V.6
-
49
-
-
34447576949
-
Evidence for carbohydrate recognition and homotypic and heterotypic binding by the TIM family
-
DOI 10.1093/intimm/dxm044
-
Wilker PR, Sedy JR, Grigura V, Murphy TL, Murphy KM. Evidence for carbohydrate recognition and homotypic and heterotypic binding by the TIM family. Int Immunol 2007 19 : 763 773. (Pubitemid 47073266)
-
(2007)
International Immunology
, vol.19
, Issue.6
, pp. 763-773
-
-
Wilker, P.R.1
Sedy, J.R.2
Grigura, V.3
Murphy, T.L.4
Murphy, K.M.5
-
50
-
-
33947359834
-
Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions
-
DOI 10.1128/JVI.01585-06
-
Tami C, et al. Immunoglobulin A (IgA) is a natural ligand of hepatitis A virus cellular receptor 1 (HAVCR1), and the association of IgA with HAVCR1 enhances virus-receptor interactions. J Virol 2007 81 : 3437 3446. (Pubitemid 46456652)
-
(2007)
Journal of Virology
, vol.81
, Issue.7
, pp. 3437-3446
-
-
Tami, C.1
Silberstein, E.2
Manangeeswaran, M.3
Freeman, G.J.4
Umetsu, S.E.5
DeKruyff, R.H.6
Umetsu, D.T.7
Kaplan, G.G.8
-
51
-
-
34249877975
-
T cell exosomes induce cholesterol accumulation in human monocytes via phosphatidylserine receptor
-
DOI 10.1002/jcp.21013
-
Zakharova L, Svetlova M, Fomina AF. T cell exosomes induce cholesterol accumulation in human monocytes via phosphatidylserine receptor. J Cell Physiol 2007 212 : 174 181. (Pubitemid 46867599)
-
(2007)
Journal of Cellular Physiology
, vol.212
, Issue.1
, pp. 174-181
-
-
Zakharova, L.1
Svetlova, M.2
Fomina, A.F.3
-
52
-
-
61849139471
-
Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells
-
Klibi J, et al. Blood diffusion and Th1-suppressive effects of galectin-9-containing exosomes released by Epstein-Barr virus-infected nasopharyngeal carcinoma cells. Blood 2009 113 : 1957 1966.
-
(2009)
Blood
, vol.113
, pp. 1957-1966
-
-
Klibi, J.1
-
53
-
-
68849129712
-
Membrane vesicles as conveyors of immune responses
-
Thery C, Ostrowski M, Segura E. Membrane vesicles as conveyors of immune responses. Nat Rev Immunol 2009 9 : 581 593.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 581-593
-
-
Thery, C.1
Ostrowski, M.2
Segura, E.3
-
54
-
-
33745133681
-
Vaccination with cell immunoglobulin mucin-1 antibodies and inactivated influenza enhances vaccine-specific lymphocyte proliferation, interferon-γ production and cross-strain reactivity
-
DOI 10.1111/j.1365-2249.2006.03107.x
-
Soo Hoo W, et al. Vaccination with cell immunoglobulin mucin-1 antibodies and inactivated influenza enhances vaccine-specific lymphocyte proliferation, interferon-gamma production and cross-strain reactivity. Clin Exp Immunol 2006 145 : 123 129. (Pubitemid 43893941)
-
(2006)
Clinical and Experimental Immunology
, vol.145
, Issue.1
, pp. 123-129
-
-
Soo Hoo, W.1
Jensen, E.R.2
Saadat, A.3
Nieto, D.4
Moss, R.B.5
Carlo, D.J.6
Moll, T.7
-
55
-
-
28444452930
-
Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma
-
Encinas JA, et al. Anti-T-cell Ig and mucin domain-containing protein 1 antibody decreases TH2 airway inflammation in a mouse model of asthma. J Allergy Clin Immunol 2005 116 : 1343 1349.
-
(2005)
J Allergy Clin Immunol
, vol.116
, pp. 1343-1349
-
-
Encinas, J.A.1
-
56
-
-
38849120861
-
Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice
-
DOI 10.1172/JCI32562
-
Degauque N, et al. Immunostimulatory Tim-1-specific antibody deprograms Tregs and prevents transplant tolerance in mice. J Clin Invest 2008 118 : 735 741. (Pubitemid 351206561)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 735-741
-
-
Degauque, N.1
Mariat, C.2
Kenny, J.3
Zhang, D.4
Gao, W.5
Minh, D.V.6
Alexopoulos, S.7
Oukka, M.8
Umetsu, D.T.9
DeKruyff, R.H.10
Kuchroo, V.11
Xin, X.Z.12
Strom, T.B.13
-
57
-
-
38849166163
-
The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model
-
DOI 10.1172/JCI32451
-
Ueno T, et al. The emerging role of T cell Ig mucin 1 in alloimmune responses in an experimental mouse transplant model. J Clin Invest 2008 118 : 742 751. (Pubitemid 351206562)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.2
, pp. 742-751
-
-
Ueno, T.1
Habicht, A.2
Clarkson, M.R.3
Albin, M.J.4
Yamaura, K.5
Boenisch, O.6
Popoola, J.7
Wang, Y.8
Yagita, H.9
Akiba, H.10
Ansari, M.J.11
Yang, J.12
Turka, L.A.13
Rothstein, D.M.14
Padera, R.F.15
Najafian, N.16
Sayegh, M.H.17
-
58
-
-
67649784846
-
Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells
-
Yuan X, et al. Targeting Tim-1 to overcome resistance to transplantation tolerance mediated by CD8 T17 cells. Proc Natl Acad Sci USA 2009 106 : 10734 10739.
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, pp. 10734-10739
-
-
Yuan, X.1
-
59
-
-
34447273787
-
Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function
-
DOI 10.1084/jem.20062498
-
Xiao S, et al. Differential engagement of Tim-1 during activation can positively or negatively costimulate T cell expansion and effector function. J Exp Med 2007 204 : 1691 1702. (Pubitemid 47048034)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.7
, pp. 1691-1702
-
-
Xiao, S.1
Najafian, N.2
Reddy, J.3
Albin, M.4
Zhu, C.5
Jensen, E.6
Imitola, J.7
Korn, T.8
Anderson, A.C.9
Zhang, Z.10
Gutierrez, C.11
Moll, T.12
Sobel, R.A.13
Umetsu, D.T.14
Yagita, H.15
Akiba, H.16
Strom, T.17
Sayegh, M.H.18
DeKruyff, R.H.19
Khoury, S.J.20
Kuchroo, V.K.21
more..
-
60
-
-
28044460035
-
T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation
-
DOI 10.1073/pnas.0508643102
-
de Souza AJ, Oriss TB, O'Malley KJ, Ray A, Kane LP. T cell Ig and mucin 1 (TIM-1) is expressed on in vivo-activated T cells and provides a costimulatory signal for T cell activation. Proc Natl Acad Sci USA 2005 102 : 17113 17118. (Pubitemid 41692692)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.47
, pp. 17113-17118
-
-
De Souza, A.J.1
Oriss, T.B.2
O'Malley, K.J.3
Ray, A.4
Kane, L.P.5
-
61
-
-
33947617935
-
Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals
-
Binne LL, Scott ML, Rennert PD. Human TIM-1 associates with the TCR complex and up-regulates T cell activation signals. J Immunol 2007 178 : 4342 4350.
-
(2007)
J Immunol
, vol.178
, pp. 4342-4350
-
-
Binne, L.L.1
Scott, M.L.2
Rennert, P.D.3
-
62
-
-
45549085191
-
T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase
-
de Souza AJ, Oak JS, Jordanhazy R, DeKruyff RH, Fruman DA, Kane LP. T cell Ig and mucin domain-1-mediated T cell activation requires recruitment and activation of phosphoinositide 3-kinase. J Immunol 2008 180 : 6518 6526.
-
(2008)
J Immunol
, vol.180
, pp. 6518-6526
-
-
De Souza, A.J.1
Oak, J.S.2
Jordanhazy, R.3
Dekruyff, R.H.4
Fruman, D.A.5
Kane, L.P.6
-
63
-
-
0037131165
-
Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration
-
DOI 10.1074/jbc.M200562200
-
Bailly V, Zhang Z, Meier W, Cate R, Sanicola M, Bonventre JV. Shedding of kidney injury molecule-1, a putative adhesion protein involved in renal regeneration. J Biol Chem 2002 277 : 39739 39748. (Pubitemid 35190957)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.42
, pp. 39739-39748
-
-
Bailly, V.1
Zhang, Z.2
Meier, W.3
Cate, R.4
Sanicola, M.5
Bonventre, J.V.6
-
64
-
-
0036314217
-
Kidney Injury Molecule-1 (KIM-1): A novel biomarker for human renal proximal tubule injury
-
DOI 10.1046/j.1523-1755.2002.00433.x
-
Han WK, Bailly V, Abichandani R, Thadhani R, Bonventre JV. Kidney Injury Molecule-1 (KIM-1): a novel biomarker for human renal proximal tubule injury. Kidney Int 2002 62 : 237 244. (Pubitemid 34754067)
-
(2002)
Kidney International
, vol.62
, Issue.1
, pp. 237-244
-
-
Han, W.K.1
Bailly, V.2
Abichandani, R.3
Thadhani, R.4
Bonventre, J.V.5
-
65
-
-
2342580141
-
Hepatitis A virus receptor blocks cell differentiation and is overexpressed in clear cell renal cell carcinoma
-
Vila MR, et al. Hepatitis A virus receptor blocks cell differentiation and is overexpressed in clear cell renal cell carcinoma. Kidney Int 2004 65 : 1761 1773.
-
(2004)
Kidney Int
, vol.65
, pp. 1761-1773
-
-
Vila, M.R.1
-
66
-
-
24344507726
-
Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma
-
Han WK, et al. Human kidney injury molecule-1 is a tissue and urinary tumor marker of renal cell carcinoma. J Am Soc Nephrol 2005 16 : 1126 1134.
-
(2005)
J Am Soc Nephrol
, vol.16
, pp. 1126-1134
-
-
Han, W.K.1
-
67
-
-
0037203867
-
Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease
-
DOI 10.1038/415536a
-
Monney L, et al. Th1-specific cell surface protein Tim-3 regulates macrophage activation and severity of an autoimmune disease. Nature 2002 415 : 536 541. (Pubitemid 34130609)
-
(2002)
Nature
, vol.415
, Issue.6871
, pp. 536-541
-
-
Monney, L.1
Sabatos, C.A.2
Gaglia, J.L.3
Ryu, A.4
Waldner, H.5
Chernova, T.6
Manning, S.7
Greenfield, E.A.8
Coyle, A.J.9
Sobel, R.A.10
Freeman, G.J.11
Kuchroo, V.K.12
-
68
-
-
0242708767
-
Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance
-
DOI 10.1038/ni987
-
Sanchez-Fueyo A, et al. Tim-3 inhibits T helper type 1-mediated auto- and alloimmune responses and promotes immunological tolerance. Nat Immunol 2003 4 : 1093 1101. (Pubitemid 37428037)
-
(2003)
Nature Immunology
, vol.4
, Issue.11
, pp. 1093-1101
-
-
Sanchez-Fueyo, A.1
Tian, J.2
Picarella, D.3
Domenig, C.4
Zheng, X.X.5
Sabatos, C.A.6
Manlongat, N.7
Bender, O.8
Kamradt, T.9
Kuchroo, V.K.10
Gutierrez-Ramos, J.-C.11
Coyle, A.J.12
Strom, T.B.13
-
69
-
-
70349248367
-
TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines
-
Hastings WD, et al. TIM-3 is expressed on activated human CD4+ T cells and regulates Th1 and Th17 cytokines. Eur J Immunol 2009 39 : 2492 2501.
-
(2009)
Eur J Immunol
, vol.39
, pp. 2492-2501
-
-
Hastings, W.D.1
-
70
-
-
36248967595
-
Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells
-
Anderson AC, et al. Promotion of tissue inflammation by the immune receptor Tim-3 expressed on innate immune cells. Science 2007 318 : 1141 1143.
-
(2007)
Science
, vol.318
, pp. 1141-1143
-
-
Anderson, A.C.1
-
71
-
-
77749304012
-
Th1 transcription factor T-bet regulates the expression of Tim-3
-
Anderson AC, et al. Th1 transcription factor T-bet regulates the expression of Tim-3. Eur J Immunol 2010 40 : 859 866.
-
(2010)
Eur J Immunol
, vol.40
, pp. 859-866
-
-
Anderson, A.C.1
-
72
-
-
36348976981
-
Structural Analysis of the Human Galectin-9 N-terminal Carbohydrate Recognition Domain Reveals Unexpected Properties that Differ from the Mouse Orthologue
-
DOI 10.1016/j.jmb.2007.09.060, PII S0022283607012089
-
Nagae M, et al. Structural analysis of the recognition mechanism of poly-N-acetyllactosamine by the human galectin-9 N-terminal carbohydrate recognition domain. Glycobiology 2009 19 : 112 117. (Pubitemid 350160685)
-
(2008)
Journal of Molecular Biology
, vol.375
, Issue.1
, pp. 119-135
-
-
Nagae, M.1
Nishi, N.2
Nakamura-Tsuruta, S.3
Hirabayashi, J.4
Wakatsuki, S.5
Kato, R.6
-
73
-
-
0036606914
-
Galectins and their ligands: Amplifiers, silencers or tuners of the inflammatory response?
-
Rabinovich GA, et al. Galectins and their ligands: amplifiers, silencers or tuners of the inflammatory response? Trends Immunol 2002 23 : 313 320.
-
(2002)
Trends Immunol
, vol.23
, pp. 313-320
-
-
Rabinovich, G.A.1
-
74
-
-
34447267678
-
Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma
-
DOI 10.1164/rccm.200608-1243OC
-
Katoh S, et al. Galectin-9 inhibits CD44-hyaluronan interaction and suppresses a murine model of allergic asthma. Am J Respir Crit Care Med 2007 176 : 27 35. (Pubitemid 47048051)
-
(2007)
American Journal of Respiratory and Critical Care Medicine
, vol.176
, Issue.1
, pp. 27-35
-
-
Katoh, S.1
Ishii, N.2
Nobumoto, A.3
Takeshita, K.4
Dai, S.-Y.5
Shinonaga, R.6
Niki, T.7
Nishi, N.8
Tominaga, A.9
Yamauchi, A.10
Hirashima, M.11
-
75
-
-
70450265476
-
Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation
-
Niki T, et al. Galectin-9 is a high affinity IgE-binding lectin with anti-allergic effect by blocking IgE-antigen complex formation. J Biol Chem 2009 284 : 32344 32352.
-
(2009)
J Biol Chem
, vol.284
, pp. 32344-32352
-
-
Niki, T.1
-
76
-
-
40849120400
-
Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis
-
Seki M, et al. Galectin-9 suppresses the generation of Th17, promotes the induction of regulatory T cells, and regulates experimental autoimmune arthritis. Clin Immunol 2008 127 : 78 88.
-
(2008)
Clin Immunol
, vol.127
, pp. 78-88
-
-
Seki, M.1
-
77
-
-
70350552096
-
Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice
-
He W, et al. Galectin-9 significantly prolongs the survival of fully mismatched cardiac allografts in mice. Transplantation 2009 88 : 782 790.
-
(2009)
Transplantation
, vol.88
, pp. 782-790
-
-
He, W.1
-
78
-
-
40849083349
-
Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts
-
Wang F, et al. Activation of Tim-3-Galectin-9 pathway improves survival of fully allogeneic skin grafts. Transpl Immunol 2008 19 : 12 19.
-
(2008)
Transpl Immunol
, vol.19
, pp. 12-19
-
-
Wang, F.1
-
79
-
-
67649958050
-
Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: A potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation
-
Niwa H, et al. Stable form of galectin-9, a Tim-3 ligand, inhibits contact hypersensitivity and psoriatic reactions: a potent therapeutic tool for Th1- and/or Th17-mediated skin inflammation. Clin Immunol 2009 132 : 184 194.
-
(2009)
Clin Immunol
, vol.132
, pp. 184-194
-
-
Niwa, H.1
-
80
-
-
45249094514
-
Phagocytic signaling: You can touch, but you can't eat
-
Kinchen JM, Ravichandran KS. Phagocytic signaling: you can touch, but you can't eat. Curr Biol 2008 18 : R521 R524.
-
(2008)
Curr Biol
, vol.18
-
-
Kinchen, J.M.1
Ravichandran, K.S.2
-
81
-
-
0022356959
-
Susceptibility of BALB/c mice carrying various DBA/2 genes to development of Friend murine leukemia virus-induced erythroleukemia
-
DOI 10.1084/jem.162.5.1579
-
Ruscetti S, Matthai R, Potter M. Susceptibility of BALB/c mice carrying various DBA/2 genes to development of Friend murine leukemia virus-induced erythroleukemia. J Exp Med 1985 162 : 1579 1587. (Pubitemid 16195360)
-
(1985)
Journal of Experimental Medicine
, vol.162
, Issue.5
, pp. 1579-1587
-
-
Ruscetti, S.1
Matthai, R.2
Potter, M.3
-
82
-
-
0242539820
-
Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance
-
Sabatos CA, et al. Interaction of Tim-3 and Tim-3 ligand regulates T helper type 1 responses and induction of peripheral tolerance. Nat Immunol 2003 4 : 1102 1110.
-
(2003)
Nat Immunol
, vol.4
, pp. 1102-1110
-
-
Sabatos, C.A.1
-
83
-
-
69449091993
-
Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells
-
Golden-Mason L, et al. Negative immune regulator Tim-3 is overexpressed on T cells in hepatitis C virus infection and its blockade rescues dysfunctional CD4+ and CD8+ T cells. J Virol 2009 83 : 9122 9130.
-
(2009)
J Virol
, vol.83
, pp. 9122-9130
-
-
Golden-Mason, L.1
-
84
-
-
58149277359
-
Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection
-
Jones RB, et al. Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection. J Exp Med 2008 205 : 2763 2779.
-
(2008)
J Exp Med
, vol.205
, pp. 2763-2779
-
-
Jones, R.B.1
-
85
-
-
33749324118
-
Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade
-
DOI 10.1084/jem.20061800
-
Freeman GJ, Wherry EJ, Ahmed R, Sharpe AH. Reinvigorating exhausted HIV-specific T cells via PD-1-PD-1 ligand blockade. J Exp Med 2006 203 : 2223 2227. (Pubitemid 44498355)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.10
, pp. 2223-2227
-
-
Freeman, G.J.1
Wherry, E.J.2
Ahmed, R.3
Sharpe, A.H.4
-
86
-
-
77951687842
-
Molecular analysis of tumor-promoting CD8(+) T cells in two-stage cutaneous chemical carcinogenesis
-
doi: 10.1038/jid.2009.362.
-
Kwong BY, et al. Molecular analysis of tumor-promoting CD8(+) T cells in two-stage cutaneous chemical carcinogenesis. J Invest Dermatol 2010 doi: 10.1038/jid.2009.362.
-
(2010)
J Invest Dermatol
-
-
Kwong, B.Y.1
-
87
-
-
33646868146
-
Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity
-
Frisancho-Kiss S, et al. Cutting edge: T cell Ig mucin-3 reduces inflammatory heart disease by increasing CTLA-4 during innate immunity. J Immunol 2006 176 : 6411 6415. (Pubitemid 43787822)
-
(2006)
Journal of Immunology
, vol.176
, Issue.11
, pp. 6411-6415
-
-
Frisancho-Kiss, S.1
Nyland, J.F.2
Davis, S.E.3
Barrett, M.A.4
Gatewood, S.J.L.5
Njoku, D.B.6
Cihakova, D.7
Silbergeld, E.K.8
Rose, N.R.9
Fairweather, D.10
-
88
-
-
33745035874
-
Dysregulated T cell expression of TIM3 in multiple sclerosis
-
DOI 10.1084/jem.20060210
-
Koguchi K, Anderson DE, Yang L, O'Connor KC, Kuchroo VK, Hafler DA. Dysregulated T cell expression of TIM3 in multiple sclerosis. J Exp Med 2006 203 : 1413 1418. (Pubitemid 43877603)
-
(2006)
Journal of Experimental Medicine
, vol.203
, Issue.6
, pp. 1413-1418
-
-
Koguchi, K.1
Anderson, D.E.2
Yang, L.3
O'Connor, K.C.4
Kuchroo, V.K.5
Hafler, D.A.6
-
89
-
-
0037110424
-
The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis
-
DOI 10.1016/S0022-510X(02)00207-1, PII S0022510X02002071
-
Minagar A, Shapshak P, Fujimura R, Ownby R, Heyes M, Eisdorfer C. The role of macrophage/microglia and astrocytes in the pathogenesis of three neurologic disorders: HIV-associated dementia, Alzheimer disease, and multiple sclerosis. J Neurol Sci 2002 202 : 13 23. (Pubitemid 36153117)
-
(2002)
Journal of the Neurological Sciences
, vol.202
, Issue.1-2
, pp. 13-23
-
-
Minagar, A.1
Shapshak, P.2
Fujimura, R.3
Ownby, R.4
Heyes, M.5
Eisdorfer, C.6
-
90
-
-
0041864080
-
Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: Termination of CNS autoimmune inflammation and modulation by interferon-beta
-
DOI 10.1002/glia.10258
-
Chan A, et al. Phagocytosis of apoptotic inflammatory cells by microglia and its therapeutic implications: termination of CNS autoimmune inflammation and modulation by interferon-beta. Glia 2003 43 : 231 242. (Pubitemid 37047679)
-
(2003)
GLIA
, vol.43
, Issue.3
, pp. 231-242
-
-
Chan, A.1
Seguin, R.2
Magnus, T.3
Papadimitriou, C.4
Toyka, K.V.5
Antel, J.P.6
Gold, R.7
-
91
-
-
1642317139
-
Role of lipid interactions in autoimmune demyelination
-
DOI 10.1016/j.bbadis.2003.10.001, PII S0925443903001650
-
Ohler B, et al. Role of lipid interactions in autoimmune demyelination. Biochim Biophys Acta 2004 1688 : 10 17. (Pubitemid 38366301)
-
(2004)
Biochimica et Biophysica Acta - Molecular Basis of Disease
, vol.1688
, Issue.1
, pp. 10-17
-
-
Ohler, B.1
Graf, K.2
Bragg, R.3
Lemons, T.4
Coe, R.5
Genain, C.6
Israelachvili, J.7
Husted, C.8
-
92
-
-
34250351866
-
Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti-Tim-3 antibody in vivo
-
DOI 10.1084/jem.20062093
-
Kearley J, McMillan SJ, Lloyd CM. Th2-driven, allergen-induced airway inflammation is reduced after treatment with anti-Tim-3 antibody in vivo. J Exp Med 2007 204 : 1289 1294. (Pubitemid 46919866)
-
(2007)
Journal of Experimental Medicine
, vol.204
, Issue.6
, pp. 1289-1294
-
-
Kearley, J.1
McMillan, S.J.2
Lloyd, C.M.3
-
93
-
-
77951672409
-
Determination of cytoplasmic tyrosine residues of TIM-3 involved in regulation of TCR signaling
-
abstract
-
Lee J, Su EW, Phuah J, Hainline S, Kane LP. Determination of cytoplasmic tyrosine residues of TIM-3 involved in regulation of TCR signaling abstract J Immunol 2009 182 : 35.
-
(2009)
J Immunol
, vol.182
, pp. 35
-
-
Lee, J.1
Su, E.W.2
Phuah, J.3
Hainline, S.4
Kane, L.P.5
-
94
-
-
1642265835
-
SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling
-
Shakhov AN, et al. SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling. Eur J Immunol 2004 34 : 494 503.
-
(2004)
Eur J Immunol
, vol.34
, pp. 494-503
-
-
Shakhov, A.N.1
-
95
-
-
42949154169
-
Bimodal regulation of T cell-mediated immune responses by TIM-4
-
DOI 10.1093/intimm/dxn029
-
Mizui M, et al. Bimodal regulation of T cell-mediated immune responses by TIM-4. Int Immunol 2008 20 : 695 708. (Pubitemid 351619237)
-
(2008)
International Immunology
, vol.20
, Issue.5
, pp. 695-708
-
-
Mizui, M.1
Shikina, T.2
Arase, H.3
Suzuki, K.4
Yasui, T.5
Rennert, P.D.6
Kumanogoh, A.7
Kikutani, H.8
-
96
-
-
35648938123
-
TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigen-specific Th2 differentiation and intestinal allergy
-
Yang PC, et al. TIM-4 expressed by mucosal dendritic cells plays a critical role in food antigen-specific Th2 differentiation and intestinal allergy. Gastroenterology 2007 133 : 1522 1533.
-
(2007)
Gastroenterology
, vol.133
, pp. 1522-1533
-
-
Yang, P.C.1
-
97
-
-
44449145064
-
TIM-4 expressed on APCs induces T cell expansion and survival
-
Rodriguez-Manzanet R, et al. TIM-4 expressed on APCs induces T cell expansion and survival. J Immunol 2008 180 : 4706 4713.
-
(2008)
J Immunol
, vol.180
, pp. 4706-4713
-
-
Rodriguez-Manzanet, R.1
-
98
-
-
67449147143
-
Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms
-
Jinushi M, et al. Milk fat globule epidermal growth factor-8 blockade triggers tumor destruction through coordinated cell-autonomous and immune-mediated mechanisms. J Exp Med 2009 206 : 1317 1326.
-
(2009)
J Exp Med
, vol.206
, pp. 1317-1326
-
-
Jinushi, M.1
-
99
-
-
60349123136
-
The phosphatidylserine receptor TIM-4 does not mediate direct signaling
-
Park D, Hochreiter-Hufford A, Ravichandran KS. The phosphatidylserine receptor TIM-4 does not mediate direct signaling. Curr Biol 2009 19 : 346 351.
-
(2009)
Curr Biol
, vol.19
, pp. 346-351
-
-
Park, D.1
Hochreiter-Hufford, A.2
Ravichandran, K.S.3
-
100
-
-
25844475970
-
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
-
Chen TT, et al. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J Exp Med 2005 202 : 955 965.
-
(2005)
J Exp Med
, vol.202
, pp. 955-965
-
-
Chen, T.T.1
-
101
-
-
0041327722
-
Immune semaphorins: A new area of semaphorin research
-
DOI 10.1242/jcs.00674
-
Kumanogoh A, Kikutani H. Immune semaphorins: a new area of semaphorin research. J Cell Sci 2003 116 : 3463 3470. (Pubitemid 37063390)
-
(2003)
Journal of Cell Science
, vol.116
, Issue.17
, pp. 3463-3470
-
-
Kumanogoh, A.1
Kikutani, H.2
-
102
-
-
0037057655
-
Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2
-
Kumanogoh A, et al. Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2. Nature 2002 419 : 629 633.
-
(2002)
Nature
, vol.419
, pp. 629-633
-
-
Kumanogoh, A.1
-
103
-
-
23744437449
-
Tim-2 regulates T helper type 2 responses and autoimmunity
-
DOI 10.1084/jem.20050308
-
Chakravarti S, et al. Tim-2 regulates T helper type 2 responses and autoimmunity. J Exp Med 2005 202 : 437 444. (Pubitemid 41126961)
-
(2005)
Journal of Experimental Medicine
, vol.202
, Issue.3
, pp. 437-444
-
-
Chakravarti, S.1
Sabatos, C.A.2
Xiao, S.3
Illes, Z.4
Cha, E.K.5
Sobel, R.A.6
Zheng, X.X.7
Strom, T.B.8
Kuchroo, V.K.9
-
104
-
-
33749134992
-
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation
-
Rennert PD, et al. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol 2006 177 : 4311 4321.
-
(2006)
J Immunol
, vol.177
, pp. 4311-4321
-
-
Rennert, P.D.1
-
105
-
-
33749505865
-
Cutting edge: Inhibition of T cell activation by TIM-2
-
Knickelbein JE, de Souza AJ, Tosti R, Narayan P, Kane LP. Cutting edge: inhibition of T cell activation by TIM-2. J Immunol 2006 177 : 4966 4970. (Pubitemid 44527565)
-
(2006)
Journal of Immunology
, vol.177
, Issue.8
, pp. 4966-4970
-
-
Knickelbein, J.E.1
De Souza, A.J.2
Tosti, R.3
Narayan, P.4
Kane, L.P.5
-
106
-
-
0030892234
-
Apoptosis by death factor
-
DOI 10.1016/S0092-8674(00)81874-7
-
Nagata S. Apoptosis by death factor. Cell 1997 88 : 355 365. (Pubitemid 27131377)
-
(1997)
Cell
, vol.88
, Issue.3
, pp. 355-365
-
-
Nagata, S.1
-
107
-
-
0033593572
-
Cell death in development
-
Vaux DL, Korsmeyer SJ. Cell death in development. Cell 1999 96 : 245 254.
-
(1999)
Cell
, vol.96
, pp. 245-254
-
-
Vaux, D.L.1
Korsmeyer, S.J.2
-
108
-
-
0034641931
-
Corpse clearance defines the meaning of cell death
-
Savill J, Fadok V. Corpse clearance defines the meaning of cell death. Nature 2000 407 : 784 788.
-
(2000)
Nature
, vol.407
, pp. 784-788
-
-
Savill, J.1
Fadok, V.2
-
109
-
-
0031778836
-
Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies
-
DOI 10.1038/ng0598-56
-
Botto M, et al. Homozygous C1q deficiency causes glomerulonephritis associated with multiple apoptotic bodies. Nat Genet 1998 19 : 56 59. (Pubitemid 28242023)
-
(1998)
Nature Genetics
, vol.19
, Issue.1
, pp. 56-59
-
-
Botto, M.1
Dell'Agnola, C.2
Bygrave, A.E.3
Thompson, E.M.4
Cook, H.T.5
Petry, F.6
Loos, M.7
Pandolfi, P.P.8
Walport, M.J.9
-
110
-
-
0034618113
-
A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo
-
Taylor PR, et al. A hierarchical role for classical pathway complement proteins in the clearance of apoptotic cells in vivo. J Exp Med 2000 192 : 359 366.
-
(2000)
J Exp Med
, vol.192
, pp. 359-366
-
-
Taylor, P.R.1
-
111
-
-
2442665179
-
Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice
-
DOI 10.1126/science.1094359
-
Hanayama R, et al. Autoimmune disease and impaired uptake of apoptotic cells in MFG-E8-deficient mice. Science 2004 304 : 1147 1150. (Pubitemid 38661849)
-
(2004)
Science
, vol.304
, Issue.5674
, pp. 1147-1150
-
-
Hanayama, R.1
Tanaka, M.2
Miyasaka, K.3
Aozasa, K.4
Koike, M.5
Uchiyama, Y.6
Nagata, S.7
-
112
-
-
0034795821
-
Phagocyte receptors for apoptotic cells: Recognition, uptake, and consequences
-
Fadok VA, Bratton DL, Henson PM. Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences. J Clin Invest 2001 108 : 957 962.
-
(2001)
J Clin Invest
, vol.108
, pp. 957-962
-
-
Fadok, V.A.1
Bratton, D.L.2
Henson, P.M.3
-
113
-
-
0035837323
-
Phagocytosis and clearance of apoptotic cells is mediated by MER
-
DOI 10.1038/35075603
-
Scott RS, et al. Phagocytosis and clearance of apoptotic cells is mediated by MER. Nature 2001 411 : 207 211. (Pubitemid 32455181)
-
(2001)
Nature
, vol.411
, Issue.6834
, pp. 207-211
-
-
Scott, R.S.1
McMahon, E.J.2
Pop, S.M.3
Reap, E.A.4
Caricchio, R.5
Cohen, P.L.6
Shelton Earp, H.7
Matsushima, G.K.8
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