-
1
-
-
0026763128
-
Identification of a set of genes with developmentally down-Regulated expression in the mouse brain
-
Kumar S, Tomooka Y, Noda M (1992) Identification of a set of genes with developmentally down-regulated expression in the mouse brain. Biochem Biophys Res Commun 185(3):1155-1161
-
(1992)
Biochem Biophys Res Commun
, vol.185
, Issue.3
, pp. 1155-1161
-
-
Kumar, S.1
Tomooka, Y.2
Noda, M.3
-
2
-
-
0027990778
-
Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 betaconverting enzyme
-
Kumar S, Kinoshita M, Noda M, Copeland NG, Jenkins NA (1994) Induction of apoptosis by the mouse Nedd2 gene, which encodes a protein similar to the product of the Caenorhabditis elegans cell death gene ced-3 and the mammalian IL-1 betaconverting enzyme. Genes Dev 8(14):1613-1626
-
(1994)
Genes Dev
, vol.8
, Issue.14
, pp. 1613-1626
-
-
Kumar, S.1
Kinoshita, M.2
Noda, M.3
Copeland, N.G.4
Jenkins, N.A.5
-
3
-
-
0028168593
-
Ich-1, an Ice/ced-3-Related gene, encodes both positive and negative regulators of programmed cell death
-
Wang L, Miura M, Bergeron L, Zhu H, Yuan J (1994) Ich-1, an Ice/ced-3-related gene, encodes both positive and negative regulators of programmed cell death. Cell 78(5): 739-750
-
(1994)
Cell
, vol.78
, Issue.5
, pp. 739-750
-
-
Wang, L.1
Miura, M.2
Bergeron, L.3
Zhu, H.4
Yuan, J.5
-
4
-
-
0032080197
-
Defects in regulation of apoptosis in caspase-2-Deficient mice
-
Bergeron L, et al. (1998) Defects in regulation of apoptosis in caspase-2-deficient mice. Genes Dev 12(9):1304-1314
-
(1998)
Genes Dev
, vol.12
, Issue.9
, pp. 1304-1314
-
-
Bergeron, L.1
-
5
-
-
65249137687
-
A tumor suppressor function for caspase-2
-
Ho LH, et al. (2009) A tumor suppressor function for caspase-2. Proc Natl Acad Sci USA 106(13):5336-5341
-
(2009)
Proc Natl Acad Sci USA
, vol.106
, Issue.13
, pp. 5336-5341
-
-
Ho, L.H.1
-
7
-
-
84863718495
-
Caspase-2 deficiency promotes aberrant DNA-Damage response and genetic instability
-
Dorstyn L, et al. (2012) Caspase-2 deficiency promotes aberrant DNA-damage response and genetic instability. Cell Death Differ 19(8):1288-1298
-
(2012)
Cell Death Differ
, vol.19
, Issue.8
, pp. 1288-1298
-
-
Dorstyn, L.1
-
8
-
-
36749022214
-
The DNA damage response: Ten years after
-
Harper JW, Elledge SJ (2007) The DNA damage response: Ten years after. Mol Cell 28(5):739-745
-
(2007)
Mol Cell
, vol.28
, Issue.5
, pp. 739-745
-
-
Harper, J.W.1
Elledge, S.J.2
-
9
-
-
79952284127
-
Hallmarks of cancer: The next generation
-
Hanahan D, Weinberg RA (2011) Hallmarks of cancer: The next generation. Cell 144(5):646-674
-
(2011)
Cell
, vol.144
, Issue.5
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
10
-
-
84875423827
-
The ATM protein kinase: Regulating the cellular response to genotoxic stress, and more
-
Shiloh Y, Ziv Y (2013) The ATM protein kinase: Regulating the cellular response to genotoxic stress, and more. Nat Rev Mol Cell Biol 14(4):197-210
-
(2013)
Nat Rev Mol Cell Biol
, vol.14
, Issue.4
, pp. 197-210
-
-
Shiloh, Y.1
Ziv, Y.2
-
11
-
-
77958191599
-
ATM activation by oxidative stress
-
Guo Z, Kozlov S, Lavin MF, Person MD, Paull TT (2010) ATM activation by oxidative stress. Science 330(6003):517-521
-
(2010)
Science
, vol.330
, Issue.6003
, pp. 517-521
-
-
Guo, Z.1
Kozlov, S.2
Lavin, M.F.3
Person, M.D.4
Paull, T.T.5
-
12
-
-
79551580561
-
ATM activates the pentose phosphate pathway promoting anti-Oxidant defence and DNA repair
-
Cosentino C, Grieco D, Costanzo V (2011) ATM activates the pentose phosphate pathway promoting anti-oxidant defence and DNA repair. EMBO J 30(3):546-555
-
(2011)
EMBO J
, vol.30
, Issue.3
, pp. 546-555
-
-
Cosentino, C.1
Grieco, D.2
Costanzo, V.3
-
13
-
-
84863720396
-
Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-Deficient mice
-
Shalini S, et al. (2012) Impaired antioxidant defence and accumulation of oxidative stress in caspase-2-deficient mice. Cell Death Differ 19(8):1370-1380
-
(2012)
Cell Death Differ
, vol.19
, Issue.8
, pp. 1370-1380
-
-
Shalini, S.1
-
14
-
-
33846202919
-
Caspase-2 deficiency enhances aging-Related traits in mice
-
Zhang Y, et al. (2007) Caspase-2 deficiency enhances aging-related traits in mice. Mech Ageing Dev 128(2):213-221
-
(2007)
Mech Ageing Dev
, vol.128
, Issue.2
, pp. 213-221
-
-
Zhang, Y.1
-
15
-
-
0029848286
-
Pleiotropic defects in ataxia-Telangiectasia protein-Deficient mice
-
Elson A, et al. (1996) Pleiotropic defects in ataxia-telangiectasia protein-deficient mice. Proc Natl Acad Sci USA 93(23):13084-13089
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, Issue.23
, pp. 13084-13089
-
-
Elson, A.1
-
16
-
-
15844426692
-
Atm-Deficient mice: A paradigm of ataxia telangiectasia
-
Barlow C, et al. (1996) Atm-deficient mice: A paradigm of ataxia telangiectasia. Cell 86(1):159-171
-
(1996)
Cell
, vol.86
, Issue.1
, pp. 159-171
-
-
Barlow, C.1
-
17
-
-
84866137255
-
PIDDosome-Independent tumor suppression by caspase-2
-
Manzl C, et al. (2012) PIDDosome-independent tumor suppression by Caspase-2. Cell Death Differ 19(10):1722-1732
-
(2012)
Cell Death Differ
, vol.19
, Issue.10
, pp. 1722-1732
-
-
Manzl, C.1
-
18
-
-
84882289067
-
Genetic deletion of caspase-2 accelerates MMTV/c-Neu-Driven mammary carcinogenesis in mice
-
Parsons MJ, et al. (2013) Genetic deletion of caspase-2 accelerates MMTV/c-neu-driven mammary carcinogenesis in mice. Cell Death Differ 20(9):1174-1182
-
(2013)
Cell Death Differ
, vol.20
, Issue.9
, pp. 1174-1182
-
-
Parsons, M.J.1
-
19
-
-
0034284341
-
Abnormal rearrangement within the alpha/delta T-Cell receptor locus in lymphomas from Atm-Deficient mice
-
Liyanage M, et al. (2000) Abnormal rearrangement within the alpha/delta T-cell receptor locus in lymphomas from Atm-deficient mice. Blood 96(5):1940-1946
-
(2000)
Blood
, vol.96
, Issue.5
, pp. 1940-1946
-
-
Liyanage, M.1
-
20
-
-
84857192718
-
Causes and consequences of aneuploidy in cancer
-
Gordon DJ, Resio B, Pellman D (2012) Causes and consequences of aneuploidy in cancer. Nat Rev Genet 13(3):189-203
-
(2012)
Nat Rev Genet
, vol.13
, Issue.3
, pp. 189-203
-
-
Gordon, D.J.1
Resio, B.2
Pellman, D.3
-
21
-
-
0036867895
-
Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification
-
Kohen R, Nyska A (2002) Oxidation of biological systems: Oxidative stress phenomena, antioxidants, redox reactions, and methods for their quantification. Toxicol Pathol 30(6):620-650
-
(2002)
Toxicol Pathol
, vol.30
, Issue.6
, pp. 620-650
-
-
Kohen, R.1
Nyska, A.2
-
22
-
-
79961176457
-
Stress-Responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling
-
Budanov AV (2011) Stress-responsive sestrins link p53 with redox regulation and mammalian target of rapamycin signaling. Antioxid Redox Signal 15(6):1679-1690
-
(2011)
Antioxid Redox Signal
, vol.15
, Issue.6
, pp. 1679-1690
-
-
Budanov, A.V.1
-
23
-
-
0035125901
-
Synthetic lethality between mutation in atm and DNA-PK (cs) during murine embryogenesis
-
Gurley KE, Kemp CJ (2001) Synthetic lethality between mutation in Atm and DNA-PK (cs) during murine embryogenesis. Curr Biol 11(3):191-194
-
(2001)
Curr Biol
, vol.11
, Issue.3
, pp. 191-194
-
-
Gurley, K.E.1
Kemp, C.J.2
-
24
-
-
0035131124
-
Early embryonic lethality in PARP-1 Atm double-Mutant mice suggests a functional synergy in cell proliferation during development
-
Ménisser-de Murcia J, Mark M, Wendling O, Wynshaw-Boris A, de Murcia G (2001) Early embryonic lethality in PARP-1 Atm double-mutant mice suggests a functional synergy in cell proliferation during development. Mol Cell Biol 21(5):1828-1832
-
(2001)
Mol Cell Biol
, vol.21
, Issue.5
, pp. 1828-1832
-
-
Ménisser-De Murcia, J.1
Mark, M.2
Wendling, O.3
Wynshaw-Boris, A.4
De Murcia, G.5
-
25
-
-
0034668060
-
Defective neurogenesis resulting from DNA ligase 4 deficiency requires atm
-
Lee Y, Barnes DE, Lindahl T, McKinnon PJ (2000) Defective neurogenesis resulting from DNA ligase 4 deficiency requires Atm. Genes Dev 14(20):2576-2580
-
(2000)
Genes Dev
, vol.14
, Issue.20
, pp. 2576-2580
-
-
Lee, Y.1
Barnes, D.E.2
Lindahl, T.3
Mckinnon, P.J.4
-
26
-
-
0031806910
-
Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice
-
Xu Y, Yang EM, Brugarolas J, Jacks T, Baltimore D (1998) Involvement of p53 and p21 in cellular defects and tumorigenesis in Atm-/- mice. Mol Cell Biol 18(7):4385-4390
-
(1998)
Mol Cell Biol
, vol.18
, Issue.7
, pp. 4385-4390
-
-
Xu, Y.1
Yang, E.M.2
Brugarolas, J.3
Jacks, T.4
Baltimore, D.5
-
27
-
-
0035266308
-
Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from atm-Deficient mice
-
Kamsler A, et al. (2001) Increased oxidative stress in ataxia telangiectasia evidenced by alterations in redox state of brains from Atm-deficient mice. Cancer Res 61(5): 1849-1854
-
(2001)
Cancer Res
, vol.61
, Issue.5
, pp. 1849-1854
-
-
Kamsler, A.1
-
28
-
-
0033578411
-
Loss of the ataxia-Telangiectasia gene product causes oxidative damage in target organs
-
Barlow C, et al. (1999) Loss of the ataxia-telangiectasia gene product causes oxidative damage in target organs. Proc Natl Acad Sci USA 96(17):9915-9919
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, Issue.17
, pp. 9915-9919
-
-
Barlow, C.1
-
29
-
-
84870882024
-
Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-Ptosis- Intellectual-Disability syndrome
-
Basel-Vanagaite L, et al. (2012) Deficiency for the ubiquitin ligase UBE3B in a blepharophimosis-ptosis-intellectual-disability syndrome. Am J Hum Genet 91(6):998-1010
-
(2012)
Am J Hum Genet
, vol.91
, Issue.6
, pp. 998-1010
-
-
Basel-Vanagaite, L.1
-
30
-
-
77956271440
-
The ATM-p53 pathway suppresses aneuploidy-Induced tumorigenesis
-
Li M, et al. (2010) The ATM-p53 pathway suppresses aneuploidy-induced tumorigenesis. Proc Natl Acad Sci USA 107(32):14188-14193
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.32
, pp. 14188-14193
-
-
Li, M.1
-
31
-
-
0036024020
-
Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both apaf-1 and caspase-9
-
O'Reilly LA, et al. (2002) Caspase-2 is not required for thymocyte or neuronal apoptosis even though cleavage of caspase-2 is dependent on both Apaf-1 and caspase-9. Cell Death Differ 9(8):832-841
-
(2002)
Cell Death Differ
, vol.9
, Issue.8
, pp. 832-841
-
-
O'Reilly, L.A.1
-
32
-
-
84855990779
-
Prenatal exposure to lipopolysaccharide results in neurodevelopmental damage that is ameliorated by zinc in mice
-
Chua JS, Cowley CJ, Manavis J, Rofe AM, Coyle P (2012) Prenatal exposure to lipopolysaccharide results in neurodevelopmental damage that is ameliorated by zinc in mice. Brain Behav Immun 26(2):326-336
-
(2012)
Brain Behav Immun
, vol.26
, Issue.2
, pp. 326-336
-
-
Chua, J.S.1
Cowley, C.J.2
Manavis, J.3
Rofe, A.M.4
Coyle, P.5
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