In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 15, 1996, Pages 7464-7469

  Fernandes Alnemri, Teresa ^a   Armstrong, Robert C ^b   Krebs, Joseph ^b   Srinivasula, Srinivasa M ^a   Wang, Lijuan ^a   Bullrich, Florencia ^a   Fritzt, Lawrence C ^b   Trapani, Joseph A ^c   Tomaselli, Kevin J ^b   Litwack, Gerald ^a   Alnemri, Emad S ^a,d  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b PFIZER INC   (United States)

^c AUSTIN RESEARCH INSTITUTE   (Australia)

^d THOMAS JEFFERSON UNIVERSITY   (United States)

Author keywords

APO 1 receptor; FAS; granzyme B; Mch2; protease cascade

Indexed keywords

ALDEHYDE; COMPLEMENTARY DNA; CYSTEINE PROTEINASE; MESSENGER RNA; PENTAPEPTIDE; SERINE PROTEINASE; TETRAPEPTIDE;

AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CELL DEATH; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LYMPHOID CELL LINE; MOLECULAR CLONING; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASE 10; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL LINE; CHROMOSOME MAPPING; CHROMOSOMES, ARTIFICIAL, YEAST; CHROMOSOMES, HUMAN, PAIR 2; CLONING, MOLECULAR; CYSTEINE ENDOPEPTIDASES; DNA PRIMERS; ENZYME ACTIVATION; HUMANS; HYBRID CELLS; KINETICS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; RECOMBINANT PROTEINS; RODENTIA; SEQUENCE HOMOLOGY, AMINO ACID; T-LYMPHOCYTES; TUMOR CELLS, CULTURED;

EID: 0344053451     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.15.7464     Document Type: Article

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