Loss of DJ-impairs antioxidant response by altered glutamine and serine metabolism

Neurobiology of Disease

Volumn 89, Issue , 2016, Pages 112-125

  Meiser, J ^a   Delcambre, S ^a   Wegner, A ^a   Jager C ^a   Ghelfi, J ^a   d'Herouel, A Fouquier ^a   Dong, X ^a   Weindl, D ^a   Stautner, C ^c   Nonnenmacher, Y ^a   Michelucci, A ^a,k   Popp, O ^j   Giesert, F ^c   Schildknecht, S ^b   Kramer L ^a   Schneider, J G ^a,i   Woitalla, D ^g   Wurst, W ^c,d,e,f   Skupin, A ^a,h   Weisenhorn, D M Vogt ^c   Kruger R ^a   Leist, M ^b   Hiller, K ^a   more..

^a UNIVERSITY OF LUXEMBOURG   (Luxembourg)

^b UNIVERSITY OF KONSTANZ   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^e UNIVERSITY OF MUNICH   (Germany)

^f TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^g ST JOSEF HOSPITAL   (Germany)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ SAARLAND UNIVERSITY   (Germany)

^j MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^k LUXEMBOURG INSTITUTE OF HEALTH   (Luxembourg)

more..

Author keywords

Folate mediated one carbon metabolism; GC MS; Glutamine; Glutathione; Mitochondrial metabolism; Oxidative stress; Parkinson's disease; ROS; Serine; Stable isotope assisted metabolomics

Indexed keywords

GLUTAMINE; SERINE; ANTIOXIDANT; PARK7 PROTEIN, MOUSE; PROTEIN DEGLYCASE DJ-1;

AMINO ACID SYNTHESIS; AMINO ACID TRANSPORT; ANIMAL CELL; ARTICLE; CASE REPORT; CELL ACTIVATION; CITRIC ACID CYCLE; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; HUMAN; HUMAN CELL; LOSS OF FUNCTION MUTATION; MALE; METABOLIC DISORDER; MICROGLIA; MITOCHONDRIAL RESPIRATION; MOUSE; NERVE CELL DEGENERATION; NERVE CELL NECROSIS; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; ONCOGENE; ONCOGENE DJ 1; OXIDATIVE STRESS; PRIORITY JOURNAL; ANIMAL; CELL CULTURE; GENETICS; METABOLISM; METABOLOME; MITOCHONDRION; NERVE CELL;

ANIMALS; ANTIOXIDANTS; CELLS, CULTURED; GLUTAMINE; HUMANS; METABOLOME; MICE; MICROGLIA; MITOCHONDRIA; NEURONS; OXIDATIVE STRESS; PROTEIN DEGLYCASE DJ-1; SERINE;

EID: 84957940543     PISSN: 09699961     EISSN: 1095953X     Source Type: Journal    
DOI: 10.1016/j.nbd.2016.01.019     Document Type: Article

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