miR-105/Runx2 axis mediates FGF2-induced ADAMTS expression in osteoarthritis cartilage

Journal of Molecular Medicine

Volumn 94, Issue 6, 2016, Pages 681-694

  Ji, Quanbo ^a   Xu, Xiaojie ^b   Xu, Yameng ^c   Fan, Zhongyi ^a   Kang, Lei ^d   Li, Ling ^b   Liang, Yingchun ^b   Guo, Jing ^b   Hong, Tian ^b   Li, Zhongli ^a   Zhang, Qiang ^a,e   Ye, Qinong ^b   Wang, Yan ^a  

^a Chinese Peoples Liberation Army General Hospital   (China)

^b BEIJING INSTITUTE OF BIOTECHNOLOGY   (China)

^c XINHUA HOSPITAL AFFILIATED TO SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d PEKING UNIVERSITY FIRST HOSPITAL   (China)

^e ROYAL LIVERPOOL UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

ADAMTS; FGF2; miR 105; Osteoarthritis; RUNX2

Indexed keywords

ADAMTS12 PROTEIN; ADAMTS7 PROTEIN; AGGRECAN; AGGRECANASE 1; AGGRECANASE 2; COLLAGEN; COLLAGEN TYPE 2 A1; FIBROBLAST GROWTH FACTOR 2; METALLOPROTEINASE; MICRORNA; MICRORNA 105; RECOMBINANT FIBROBLAST GROWTH FACTOR; TRANSCRIPTION FACTOR RELA; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG; ACAN PROTEIN, HUMAN; ADAMTS PROTEIN; ADAMTS12 PROTEIN, HUMAN; ADAMTS7 PROTEIN, HUMAN; COL2A1 PROTEIN, HUMAN; COLLAGEN TYPE 2; MIRN105 MICRORNA, HUMAN; RELA PROTEIN, HUMAN; RUNX2 PROTEIN, HUMAN;

AGED; ARTICLE; ARTICULAR CARTILAGE; CARTILAGE CELL; CLINICAL ARTICLE; COLLAGEN DEGRADATION; DOWN REGULATION; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; KNEE ARTHROPLASTY; KNEE OSTEOARTHRITIS; MALE; MICROARRAY ANALYSIS; MOLECULAR PATHOLOGY; PROMOTER REGION; PROTEIN EXPRESSION; CHONDROCYTE; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; KNEE REPLACEMENT; METABOLISM; MIDDLE AGED; NUCLEOTIDE SEQUENCE; PATHOLOGY; PRIMARY CELL CULTURE; SIGNAL TRANSDUCTION;

ADAMTS PROTEINS; ADAMTS7 PROTEIN; AGED; AGGRECANS; ARTHROPLASTY, REPLACEMENT, KNEE; BASE SEQUENCE; CARTILAGE, ARTICULAR; CHONDROCYTES; COLLAGEN TYPE II; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FEMALE; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; HUMANS; MALE; MICROARRAY ANALYSIS; MICRORNAS; MIDDLE AGED; OSTEOARTHRITIS, KNEE; PRIMARY CELL CULTURE; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTOR RELA;

EID: 84955578756     PISSN: 09462716     EISSN: 14321440     Source Type: Journal    
DOI: 10.1007/s00109-016-1380-9     Document Type: Article

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