메뉴 건너뛰기




Volumn 5, Issue 1, 2009, Pages 38-45

The role of ADAMTS-7 and ADAMTS-12 in the pathogenesis of arthritis

Author keywords

[No Author keywords available]

Indexed keywords

ADAMTS 12 PROTEIN; ADAMTS 7 PROTEIN; ALPHA 2 MACROGLOBULIN; CARTILAGE OLIGOMERIC MATRIX PROTEIN; GLUTATHIONE TRANSFERASE; INTERLEUKIN 1BETA; METALLOPROTEINASE; PROGRANULIN; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG;

EID: 58049208298     PISSN: 17458382     EISSN: 17458390     Source Type: Journal    
DOI: 10.1038/ncprheum0961     Document Type: Review
Times cited : (77)

References (64)
  • 1
    • 0036242405 scopus 로고    scopus 로고
    • Leech thrombin inhibitors
    • Salzet M (2002) Leech thrombin inhibitors. Curr Pharm Des 8: 493-503
    • (2002) Curr Pharm Des , vol.8 , pp. 493-503
    • Salzet, M.1
  • 2
    • 0026671581 scopus 로고
    • Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage
    • Hedbom E et al. (1992) Cartilage matrix proteins. An acidic oligomeric protein (COMP) detected only in cartilage. J Biol Chem 267: 6132-6136
    • (1992) J Biol Chem , vol.267 , pp. 6132-6136
    • Hedbom, E.1
  • 3
    • 0029070079 scopus 로고
    • Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene
    • Briggs MD et al. (1995) Pseudoachondroplasia and multiple epiphyseal dysplasia due to mutations in the cartilage oligomeric matrix protein gene. Nat Genet 10: 330-336
    • (1995) Nat Genet , vol.10 , pp. 330-336
    • Briggs, M.D.1
  • 4
    • 17344374325 scopus 로고    scopus 로고
    • Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoa-chondroplasia-multiple epiphyseal dysplasia disease spectrum
    • Briggs MD et al. (1998) Diverse mutations in the gene for cartilage oligomeric matrix protein in the pseudoa-chondroplasia-multiple epiphyseal dysplasia disease spectrum. Am J Hum Genet 62: 311-319
    • (1998) Am J Hum Genet , vol.62 , pp. 311-319
    • Briggs, M.D.1
  • 5
    • 0029773355 scopus 로고    scopus 로고
    • Mutations in the cartilage oligomeric matrix protein (COMP) gene in pseudoachondroplasia and multiple epiphyseal dysplasia
    • Cohn DH et al. (1996) Mutations in the cartilage oligomeric matrix protein (COMP) gene in pseudoachondroplasia and multiple epiphyseal dysplasia. Ann NY Acad Sci 785: 188-194
    • (1996) Ann NY Acad Sci , vol.785 , pp. 188-194
    • Cohn, D.H.1
  • 6
    • 0029035708 scopus 로고
    • Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia
    • Hecht JT et al. (1995) Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia. Nat Genet 10: 325-329
    • (1995) Nat Genet , vol.10 , pp. 325-329
    • Hecht, J.T.1
  • 7
    • 0031417719 scopus 로고    scopus 로고
    • Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation
    • Neidhairt M et al. (1997) Small fragments of cartilage oligomeric matrix protein in synovial fluid and serum as markers for cartilage degradation. Br J Rheumatol 36: 1151-1160
    • (1997) Br J Rheumatol , vol.36 , pp. 1151-1160
    • Neidhairt, M.1
  • 8
    • 0026660250 scopus 로고
    • Cartilage oligomeric matrix protein: A novel marker of cartilage turnover detectable in synovial fluid and blood
    • Saxne T and Heinegard D (1992) Cartilage oligomeric matrix protein: A novel marker of cartilage turnover detectable in synovial fluid and blood. Br J Rheumatol 31: 583-591
    • (1992) Br J Rheumatol , vol.31 , pp. 583-591
    • Saxne, T.1    Heinegard, D.2
  • 9
    • 0032217320 scopus 로고    scopus 로고
    • Inhibition of interleukin-1α-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitor: Potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid
    • Ganu V et al. (1998) Inhibition of interleukin-1α-induced cartilage oligomeric matrix protein degradation in bovine articular cartilage by matrix metalloproteinase inhibitor: Potential role for matrix metalloproteinases in the generation of cartilage oligomeric matrix protein fragments in arthritic synovial fluid. Arthritis Rheum 41: 2143-2151
    • (1998) Arthritis Rheum , vol.41 , pp. 2143-2151
    • Ganu, V.1
  • 10
    • 0034726067 scopus 로고    scopus 로고
    • Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP)
    • Stracke JO et al. (2000) Matrix metalloproteinases 19 and 20 cleave aggrecan and cartilage oligomeric matrix protein (COMP). FEBS Lett 478: 52-56
    • (2000) FEBS Lett , vol.478 , pp. 52-56
    • Stracke, J.O.1
  • 11
    • 0038349637 scopus 로고    scopus 로고
    • Cleavage of cartilage oligomeric matrix protein (thrombospondin-5) by matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin motifs
    • Dickinson SC et al. (2003) Cleavage of cartilage oligomeric matrix protein (thrombospondin-5) by matrix metalloproteinases and a disintegrin and metalloproteinase with thrombospondin motifs. Matrix Biol 22: 267-278
    • (2003) Matrix Biol , vol.22 , pp. 267-278
    • Dickinson, S.C.1
  • 12
    • 33845702259 scopus 로고    scopus 로고
    • ADAMTS-7: A metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein
    • Liu CJ et al. (2006) ADAMTS-7: A metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein. FASEB J 20: 988-990
    • (2006) FASEB J , vol.20 , pp. 988-990
    • Liu, C.J.1
  • 13
    • 33744909868 scopus 로고    scopus 로고
    • ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein
    • Liu CJ et al. (2006) ADAMTS-12 associates with and degrades cartilage oligomeric matrix protein. J Biol Chem 281: 151800-151808
    • (2006) J Biol Chem , vol.281 , pp. 151800-151808
    • Liu, C.J.1
  • 14
    • 4143112912 scopus 로고    scopus 로고
    • A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: The ADAMTS family
    • Apte SS (2004) A disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motifs: The ADAMTS family. Int J Biochem Cell Biol 36: 981-985
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 981-985
    • Apte, S.S.1
  • 15
    • 33750294963 scopus 로고    scopus 로고
    • Role of aggrecanase 1 in Lyme arthritis
    • Behera AK et al. (2006) Role of aggrecanase 1 in Lyme arthritis. Arthritis Rheum 54: 3319-3329
    • (2006) Arthritis Rheum , vol.54 , pp. 3319-3329
    • Behera, A.K.1
  • 16
    • 3543043776 scopus 로고    scopus 로고
    • ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage
    • Collins-Racie LA et al. (2004) ADAMTS-8 exhibits aggrecanase activity and is expressed in human articular cartilage. Matrix Biol 23: 219-230
    • (2004) Matrix Biol , vol.23 , pp. 219-230
    • Collins-Racie, L.A.1
  • 17
    • 18644370594 scopus 로고    scopus 로고
    • ADAMTS-9 is synergistically induced by interleukin-1β and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes
    • Demircan K et al. (2005) ADAMTS-9 is synergistically induced by interleukin-1β and tumor necrosis factor alpha in OUMS-27 chondrosarcoma cells and in human chondrocytes. Arthritis Rheum 52: 1451-1460
    • (2005) Arthritis Rheum , vol.52 , pp. 1451-1460
    • Demircan, K.1
  • 18
    • 15844413814 scopus 로고    scopus 로고
    • Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis
    • Glasson SS et al. (2005) Deletion of active ADAMTS5 prevents cartilage degradation in a murine model of osteoarthritis. Nature 434: 644-648
    • (2005) Nature , vol.434 , pp. 644-648
    • Glasson, S.S.1
  • 19
    • 4043154293 scopus 로고    scopus 로고
    • Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice
    • Glasson SS et al. (2004) Characterization of and osteoarthritis susceptibility in ADAMTS-4-knockout mice. Arthritis Rheum 50 2547-2558
    • (2004) Arthritis Rheum , vol.50 , pp. 2547-2558
    • Glasson, S.S.1
  • 20
    • 14244250200 scopus 로고    scopus 로고
    • The ADAMTS metalloproteinases
    • Porter S et al. (2005) The ADAMTS metalloproteinases. Biochem J 386: 15-27
    • (2005) Biochem J , vol.386 , pp. 15-27
    • Porter, S.1
  • 21
    • 0035807348 scopus 로고    scopus 로고
    • Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura
    • Levy GG et al. (2001) Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 413 488-494
    • (2001) Nature , vol.413 , pp. 488-494
    • Levy, G.G.1
  • 22
    • 0033358540 scopus 로고    scopus 로고
    • Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinasee gene
    • Colige A et al. (1999) Human Ehlers-Danlos syndrome type VII C and bovine dermatosparaxis are caused by mutations in the procollagen I N-proteinasee gene. Am J Hum Genet 65: 308-317
    • (1999) Am J Hum Genet , vol.65 , pp. 308-317
    • Colige, A.1
  • 23
    • 0033551844 scopus 로고    scopus 로고
    • Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family
    • Abbaszade i et al. (1999) Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. J Biol Chem 274: 23443-23450
    • (1999) J Biol Chem , vol.274 , pp. 23443-23450
    • Abbaszade i1
  • 24
    • 0027445981 scopus 로고
    • The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis
    • Lohmander LS et al. (1993) The structure of aggrecan fragments in human synovial fluid. Evidence that aggrecanase mediates cartilage degradation in inflammatory joint disease, joint injury, and osteoarthritis. Arthritis Rheum 36: 1214-1222
    • (1993) Arthritis Rheum , vol.36 , pp. 1214-1222
    • Lohmander, L.S.1
  • 25
    • 0037151084 scopus 로고    scopus 로고
    • Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage
    • Malfait AM et al. (2002) Inhibition of ADAM-TS4 and ADAM-TS5 prevents aggrecan degradation in osteoarthritic cartilage. J Biol Chem 277: 22201-22208
    • (2002) J Biol Chem , vol.277 , pp. 22201-22208
    • Malfait, A.M.1
  • 26
    • 0035884605 scopus 로고    scopus 로고
    • Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo
    • Sandy JD and Verscharen C (2001) Analysis of aggrecan in human knee cartilage and synovial fluid indicates that aggrecanase (ADAMTS) activity is responsible for the catabolic turnover and loss of whole aggrecan whereas other protease activity is required for C-terminal processing in vivo. Biochem J 358: 615-626
    • (2001) Biochem J , vol.358 , pp. 615-626
    • Sandy, J.D.1    Verscharen, C.2
  • 27
    • 0345211445 scopus 로고    scopus 로고
    • Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins
    • Tortorella MID et al. (1999) Purification and cloning of aggrecanase-1: A member of the ADAMTS family of proteins. Science 284: 1664-1666
    • (1999) Science , vol.284 , pp. 1664-1666
    • Tortorella, M.I.D.1
  • 28
    • 33646551230 scopus 로고    scopus 로고
    • Fine mapping of the keratoconus with cataract locus on chromosome 15q and candidate gene analysis
    • Dash DP et al. (2006) Fine mapping of the keratoconus with cataract locus on chromosome 15q and candidate gene analysis. Mol Vis 12: 499-505
    • (2006) Mol Vis , vol.12 , pp. 499-505
    • Dash, D.P.1
  • 29
    • 0028090357 scopus 로고
    • Cartilaqe oligomeric matrix protein (COMP) is an abundant component of tendon
    • DiGesare P et al. (1994) Cartilaqe oligomeric matrix protein (COMP) is an abundant component of tendon. FEBS Lett 354: 237-240
    • (1994) FEBS Lett , vol.354 , pp. 237-240
    • DiGesare, P.1
  • 30
    • 58049203639 scopus 로고    scopus 로고
    • Tumor-specific urinary matrix metalloproteinase fingerprinting: Identification of high molecular weight urinary matrix metalloproteinase species
    • Roy R et al. (2008) Tumor-specific urinary matrix metalloproteinase fingerprinting: Identification of high molecular weight urinary matrix metalloproteinase species. Clin Cancer Res 14: 6610-6617
    • (2008) Clin Cancer Res , vol.14 , pp. 6610-6617
    • Roy, R.1
  • 31
    • 33746572328 scopus 로고    scopus 로고
    • Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci
    • Kurz T et al. (2006) Fine mapping and positional candidate studies on chromosome 5p13 identify multiple asthma susceptibility loci. J Allergy Clin Immunol 118: 396-402
    • (2006) J Allergy Clin Immunol , vol.118 , pp. 396-402
    • Kurz, T.1
  • 32
    • 36249015281 scopus 로고    scopus 로고
    • The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway
    • Llamazares M et al. (2007) The ADAMTS12 metalloproteinase exhibits anti-tumorigenic properties through modulation of the Ras-dependent ERK signalling pathway. J Cell Sci 120: 3544-3552
    • (2007) J Cell Sci , vol.120 , pp. 3544-3552
    • Llamazares, M.1
  • 33
    • 4143129884 scopus 로고    scopus 로고
    • ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a micin domain
    • Somerville RP et al. (2004) ADAMTS7B, the full-length product of the ADAMTS7 gene, is a chondroitin sulfate proteoglycan containing a micin domain. J Biol Chem 279: 35159-35175
    • (2004) J Biol Chem , vol.279 , pp. 35159-35175
    • Somerville, R.P.1
  • 34
    • 0035947652 scopus 로고    scopus 로고
    • Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats
    • Cal S et al. (2001) Identification, characterization, and intracellular processing of ADAM-TS12, a novel human disintegrin with a complex structural organization involving multiple thrombospondin-1 repeats. J Biol Chem 276: 17932-17940
    • (2001) J Biol Chem , vol.276 , pp. 17932-17940
    • Cal, S.1
  • 35
    • 9144230209 scopus 로고    scopus 로고
    • Expression profiling of metalloproteinases and their inhibitors in cartilage
    • Kevorkian L et al. (2004) Expression profiling of metalloproteinases and their inhibitors in cartilage. Arthritis Rheum 50: 131-141
    • (2004) Arthritis Rheum , vol.50 , pp. 131-141
    • Kevorkian, L.1
  • 36
    • 0029018708 scopus 로고
    • Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system
    • Hollenberg SM et al. (1995) Identification of a new family of tissue-specific basic helix-loop-helix proteins with a two-hybrid system. Mol Cell Biol 15: 3813-3822
    • (1995) Mol Cell Biol , vol.15 , pp. 3813-3822
    • Hollenberg, S.M.1
  • 37
    • 0035378502 scopus 로고    scopus 로고
    • Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN)
    • Liu CJ (2001) Fibroblast growth factor homologous factor 1B binds to the C terminus of the tetrodotoxin-resistant sodium channel rNav1.9a (NaN). J Biol Chem 276: 18925-18933
    • (2001) J Biol Chem , vol.276 , pp. 18925-18933
    • Liu, C.J.1
  • 38
    • 0027250250 scopus 로고
    • Mammalian Ras interacts directly with the serine/threonine kinase Raf
    • Vojtek AB et al. (1993) Mammalian Ras interacts directly with the serine/threonine kinase Raf. Cell 74: 205-214
    • (1993) Cell , vol.74 , pp. 205-214
    • Vojtek, A.B.1
  • 39
    • 0038644928 scopus 로고    scopus 로고
    • Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain
    • Llamazares M et al. (2003) Identification and characterization of ADAMTS-20 defines a novel subfamily of metalloproteinases-disintegrins with multiple thrombospondin-1 repeats and a unique GON domain. J Biol Chem 278: 13382-13389
    • (2003) J Biol Chem , vol.278 , pp. 13382-13389
    • Llamazares, M.1
  • 40
    • 53949093715 scopus 로고    scopus 로고
    • Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin
    • Luan Y et al. (2008) Inhibition of ADAMTS-7 and ADAMTS-12 degradation of cartilage oligomeric matrix protein by alpha-2-macroglobulin. Osteoarthritis Cartilage 16: 1413-1420
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 1413-1420
    • Luan, Y.1
  • 41
    • 0037446206 scopus 로고    scopus 로고
    • Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: Transcriptional regulation by TNFα
    • Bevitt DJ et al. (2003) Expression of ADAMTS metalloproteinases in the retinal pigment epithelium derived cell line ARPE-19: transcriptional regulation by TNFα. Biochim Biophys Acta 1626 83-91
    • (2003) Biochim Biophys Acta , vol.1626 , pp. 83-91
    • Bevitt, D.J.1
  • 42
    • 33646571571 scopus 로고    scopus 로고
    • ADAMTS-1 and -4 are upregulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes
    • Cross AK et al. (2006) ADAMTS-1 and -4 are upregulated following transient middle cerebral artery occlusion in the rat and their expression is modulated by TNF in cultured astrocytes. Brain Res 1088: 19-30
    • (2006) Brain Res , vol.1088 , pp. 19-30
    • Cross, A.K.1
  • 43
    • 0037414930 scopus 로고    scopus 로고
    • Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-α, TNF-α converting enzyme and ADAMTS family members in murine fat territories
    • Voros G et al. (2003) Differential expression of plasminogen activator inhibitor-1, tumor necrosis factor-α, TNF-α converting enzyme and ADAMTS family members in murine fat territories. Biochim Biophys Acta 1625: 36-42
    • (2003) Biochim Biophys Acta , vol.1625 , pp. 36-42
    • Voros, G.1
  • 44
    • 15844384854 scopus 로고    scopus 로고
    • ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro
    • Stanton H et al. (2005) ADAMTS5 is the major aggrecanase in mouse cartilage in vivo and in vitro. Nature 434: 648-652
    • (2005) Nature , vol.434 , pp. 648-652
    • Stanton, H.1
  • 45
    • 0024333351 scopus 로고
    • Alpha-macroglobulins: Structure, shape, and mechanism of proteinase complex formation
    • Sottrup-jensen L (1989) Alpha-macroglobulins: Structure, shape, and mechanism of proteinase complex formation. J Biol Chem 264: 11539-11542
    • (1989) J Biol Chem , vol.264 , pp. 11539-11542
    • Sottrup-jensen, L.1
  • 46
    • 0027076834 scopus 로고
    • Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics
    • Borth W (1992) Alpha 2-macroglobulin, a multifunctional binding protein with targeting characteristics. Faseb J 6: 3345-3353
    • (1992) Faseb J , vol.6 , pp. 3345-3353
    • Borth, W.1
  • 47
    • 0027981691 scopus 로고
    • PU. 1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter
    • Feinman R et al. (1994) PU. 1 and an HLH family member contribute to the myeloid-specific transcription of the Fc gamma RIIIA promoter. Embo J 13: 3852-3860
    • (1994) Embo J , vol.13 , pp. 3852-3860
    • Feinman, R.1
  • 48
    • 2342445246 scopus 로고    scopus 로고
    • Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes
    • Tortorella MD et al. (2004) Alpha2-macroglobulin is a novel substrate for ADAMTS-4 and ADAMTS-5 and represents an endogenous inhibitor of these enzymes. J Biol Chem 279: 17554-17561
    • (2004) J Biol Chem , vol.279 , pp. 17554-17561
    • Tortorella, M.D.1
  • 49
    • 34249683186 scopus 로고    scopus 로고
    • Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation
    • Xu K et al. (2007) Cartilage oligomeric matrix protein associates with granulin-epithelin precursor (GEP) and potentiates GEP-stimulated chondrocyte proliferation. J Biol Chem 282: 11347-11355
    • (2007) J Biol Chem , vol.282 , pp. 11347-11355
    • Xu, K.1
  • 50
    • 0024576880 scopus 로고
    • Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD
    • Wright WE et al. (1989) Myogenin, a factor regulating myogenesis, has a domain homologous to MyoD. Cell 56: 607-617
    • (1989) Cell , vol.56 , pp. 607-617
    • Wright, W.E.1
  • 51
    • 0027241980 scopus 로고
    • Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly turnorigenic cell line
    • Zhou J et al. (1993) Purification of an autocrine growth factor homologous with mouse epithelin precursor from a highly turnorigenic cell line. J Biol Chem 268: 10863-10869
    • (1993) J Biol Chem , vol.268 , pp. 10863-10869
    • Zhou, J.1
  • 52
    • 0025248770 scopus 로고
    • Acrosome biogenesis begins during meiosis: Evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis
    • Anakwe OO and Gerton GL (1990) Acrosome biogenesis begins during meiosis: Evidence from the synthesis and distribution of an acrosomal glycoprotein, acrogranin, during guinea pig spermatogenesis. Biol Reprod 42: 317-328
    • (1990) Biol Reprod , vol.42 , pp. 317-328
    • Anakwe, O.O.1    Gerton, G.L.2
  • 53
    • 0142063028 scopus 로고    scopus 로고
    • Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis
    • Ong CH and Bateman A (2003) Progranulin (granulin-epithelin precursor, PC-cell derived growth factor, acrogranin) in proliferation and tumorigenesis. Histol Histopathol 18: 1275-1288
    • (2003) Histol Histopathol , vol.18 , pp. 1275-1288
    • Ong, C.H.1    Bateman, A.2
  • 54
    • 2342596394 scopus 로고    scopus 로고
    • Granulin-epithelin precursor is a novel prognostic marker in epithelial ovarian carcinoma
    • Davidson B et al. (2004) Granulin-epithelin precursor is a novel prognostic marker in epithelial ovarian carcinoma. Cancer 100 2139-2147
    • (2004) Cancer , vol.100 , pp. 2139-2147
    • Davidson, B.1
  • 55
    • 0342646917 scopus 로고    scopus 로고
    • Differential gene expression in synovium of rheumatoid arthritis and osteoarthritis
    • Justen HP et al. (2000) Differential gene expression in synovium of rheumatoid arthritis and osteoarthritis. Mol Cell Biol Res Commun 3: 165-172
    • (2000) Mol Cell Biol Res Commun , vol.3 , pp. 165-172
    • Justen, H.P.1
  • 56
    • 0037074016 scopus 로고    scopus 로고
    • Conversion of proepithelin to epithelins: Roles ot SLPI and elastase in host defense and wound repair
    • Zhu J et al. (2002) Conversion of proepithelin to epithelins: roles ot SLPI and elastase in host defense and wound repair. Cell 111: 867-878
    • (2002) Cell , vol.111 , pp. 867-878
    • Zhu, J.1
  • 57
    • 0345280719 scopus 로고    scopus 로고
    • Purification of granulin-like polypeptide from the blood-sucking leech, Hirudo nipponia
    • Hong SJ and Kang KW (1999) Purification of granulin-like polypeptide from the blood-sucking leech, Hirudo nipponia. Protein Expr Purif 16: 340-346
    • (1999) Protein Expr Purif , vol.16 , pp. 340-346
    • Hong, S.J.1    Kang, K.W.2
  • 58
    • 0015896128 scopus 로고
    • The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism
    • Barrett AJ and Starkey PM (1973) The interaction of alpha 2-macroglobulin with proteinases. Characteristics and specificity of the reaction, and a hypothesis concerning its molecular mechanism. Biochem J 133: 709-724
    • (1973) Biochem J , vol.133 , pp. 709-724
    • Barrett, A.J.1    Starkey, P.M.2
  • 59
    • 0026766682 scopus 로고
    • Proteoglycans from the swarm rat chondrosarcoma. Structure of the aggregates extracted with associative and dissociative solvents as revealed by electron microscopy
    • Morgelin M et al. (1992) Proteoglycans from the swarm rat chondrosarcoma. Structure of the aggregates extracted with associative and dissociative solvents as revealed by electron microscopy. J Biol Chem 267: 14275-14284
    • (1992) J Biol Chem , vol.267 , pp. 14275-14284
    • Morgelin, M.1
  • 60
    • 0026499722 scopus 로고
    • COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins
    • Oldberg A et al. (1992) COMP (cartilage oligomeric matrix protein) is structurally related to the thrombospondins.J Biol Chem 267 22346-22350
    • (1992) J Biol Chem , vol.267 , pp. 22346-22350
    • Oldberg, A.1
  • 61
    • 42149127678 scopus 로고    scopus 로고
    • Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis
    • Chaganti RK et al. (2008) Change in serum measurements of cartilage oligomeric matrix protein and association with the development and worsening of radiographic hip osteoarthritis. Osteoarthritis Cartilage 16: 566-571
    • (2008) Osteoarthritis Cartilage , vol.16 , pp. 566-571
    • Chaganti, R.K.1
  • 62
    • 44849119804 scopus 로고    scopus 로고
    • de Jong et al. (2008) Value of serum cartilage oligomeric matrix protein as a prognostic marker of large-joint damage in rheumatoid arthritis - data from the RAPIT study. Rheumatology (Oxford) 47 868-871
    • de Jong et al. (2008) Value of serum cartilage oligomeric matrix protein as a prognostic marker of large-joint damage in rheumatoid arthritis - data from the RAPIT study. Rheumatology (Oxford) 47 868-871
  • 63
    • 48949117142 scopus 로고    scopus 로고
    • Measurement ot biomarkers in juvenile idiopathic arthritis patients and their significant association with disease severity: A comparative study
    • Gilliam BE et al. (2008) Measurement ot biomarkers in juvenile idiopathic arthritis patients and their significant association with disease severity: A comparative study. Clin Exp Rheumatol 26 492-497
    • (2008) Clin Exp Rheumatol , vol.26 , pp. 492-497
    • Gilliam, B.E.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.