-
1
-
-
18244427699
-
Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1)
-
10.1002/1529-0131(200003)43:3<673::AID-ANR25>3.0.CO;2-8, 10728762
-
Dahlberg L, Billinghurst RC, Manner P, Nelson F, Webb G, Ionescu M, Reiner A, Tanzer M, Zukor D, Chen J, van Wart HE, Poole AR. Selective enhancement of collagenase-mediated cleavage of resident type II collagen in cultured osteoarthritic cartilage and arrest with a synthetic inhibitor that spares collagenase 1 (matrix metalloproteinase 1). Arthritis Rheum 2000, 43:673-682. 10.1002/1529-0131(200003)43:3<673::AID-ANR25>3.0.CO;2-8, 10728762.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 673-682
-
-
Dahlberg, L.1
Billinghurst, R.C.2
Manner, P.3
Nelson, F.4
Webb, G.5
Ionescu, M.6
Reiner, A.7
Tanzer, M.8
Zukor, D.9
Chen, J.10
van Wart, H.E.11
Poole, A.R.12
-
2
-
-
0034840936
-
The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation
-
10.1053/joca.2001.0427, 11520168
-
Tortorella MD, Malfait AM, Deccico C, Arner E. The role of ADAM-TS4 (aggrecanase-1) and ADAM-TS5 (aggrecanase-2) in a model of cartilage degradation. Osteoarthr Cartil 2001, 9:539-552. 10.1053/joca.2001.0427, 11520168.
-
(2001)
Osteoarthr Cartil
, vol.9
, pp. 539-552
-
-
Tortorella, M.D.1
Malfait, A.M.2
Deccico, C.3
Arner, E.4
-
3
-
-
0242580819
-
Aggrecan protects cartilage collagen from proteolytic cleavage
-
10.1074/jbc.M303737200, 12890681
-
Pratta MA, Yao W, Decicco C, Tortorella MD, Liu RQ, Copeland RA, Magolda R, Newton RC, Trzaskos JM, Arner EC. Aggrecan protects cartilage collagen from proteolytic cleavage. J Biol Chem 2003, 278:45539-45545. 10.1074/jbc.M303737200, 12890681.
-
(2003)
J Biol Chem
, vol.278
, pp. 45539-45545
-
-
Pratta, M.A.1
Yao, W.2
Decicco, C.3
Tortorella, M.D.4
Liu, R.Q.5
Copeland, R.A.6
Magolda, R.7
Newton, R.C.8
Trzaskos, J.M.9
Arner, E.C.10
-
4
-
-
14244250200
-
The ADAMTS metalloproteinases
-
10.1042/BJ20040424, 1134762, 15554875
-
Porter S, Clark IM, Kevorkian L, Edwards DR. The ADAMTS metalloproteinases. Biochem J 2005, 386:15-27. 10.1042/BJ20040424, 1134762, 15554875.
-
(2005)
Biochem J
, vol.386
, pp. 15-27
-
-
Porter, S.1
Clark, I.M.2
Kevorkian, L.3
Edwards, D.R.4
-
5
-
-
30544436016
-
A contentious issue finds some clarity: on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis
-
Sandy JD. A contentious issue finds some clarity: on the independent and complementary roles of aggrecanase activity and MMP activity in human joint aggrecanolysis. Osteoarthr Cartil 2006, 14:95-100.
-
(2006)
Osteoarthr Cartil
, vol.14
, pp. 95-100
-
-
Sandy, J.D.1
-
6
-
-
33847010576
-
Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5
-
10.1002/art.22334, 17265492
-
Song RH, Tortorella MD, Malfait AM, Alston JT, Yang Z, Arner EC, Griggs DW. Aggrecan degradation in human articular cartilage explants is mediated by both ADAMTS-4 and ADAMTS-5. Arthritis Rheum 2007, 56:575-585. 10.1002/art.22334, 17265492.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 575-585
-
-
Song, R.H.1
Tortorella, M.D.2
Malfait, A.M.3
Alston, J.T.4
Yang, Z.5
Arner, E.C.6
Griggs, D.W.7
-
7
-
-
35148882630
-
Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage
-
10.1111/j.1440-1827.2007.02167.x, 17922681
-
Naito S, Shiomi T, Okada A, Kimura T, Chijiiwa M, Fujita Y, Yatabe T, Komiya K, Enomoto H, Fujikawa K, Okada Y. Expression of ADAMTS4 (aggrecanase-1) in human osteoarthritic cartilage. Pathol Int 2007, 57:703-711. 10.1111/j.1440-1827.2007.02167.x, 17922681.
-
(2007)
Pathol Int
, vol.57
, pp. 703-711
-
-
Naito, S.1
Shiomi, T.2
Okada, A.3
Kimura, T.4
Chijiiwa, M.5
Fujita, Y.6
Yatabe, T.7
Komiya, K.8
Enomoto, H.9
Fujikawa, K.10
Okada, Y.11
-
8
-
-
52949117087
-
The effect of hyaluronic acid on IL-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis
-
10.1002/jor.20683, 18524010
-
Zhou PH, Liu SQ, Peng H. The effect of hyaluronic acid on IL-1beta-induced chondrocyte apoptosis in a rat model of osteoarthritis. J Orthop Res 2008, 26:1643-1648. 10.1002/jor.20683, 18524010.
-
(2008)
J Orthop Res
, vol.26
, pp. 1643-1648
-
-
Zhou, P.H.1
Liu, S.Q.2
Peng, H.3
-
9
-
-
0034564348
-
Osteoarthritis and cartilage: the role of cytokines
-
10.1007/s11926-000-0021-y, 11123098
-
Goldring MB. Osteoarthritis and cartilage: the role of cytokines. Curr Rheumatol Rep 2000, 2:459-465. 10.1007/s11926-000-0021-y, 11123098.
-
(2000)
Curr Rheumatol Rep
, vol.2
, pp. 459-465
-
-
Goldring, M.B.1
-
10
-
-
33745044261
-
Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes
-
Lopez-Armada MJ, Carames B, Lires-Dean M, Cillero-Pastor B, Ruiz-Romero C, Galdo F, Blanco FJ. Cytokines, tumor necrosis factor-alpha and interleukin-1beta, differentially regulate apoptosis in osteoarthritis cultured human chondrocytes. Osteoarthrs Cartil 2006, 14:660-669.
-
(2006)
Osteoarthrs Cartil
, vol.14
, pp. 660-669
-
-
Lopez-Armada, M.J.1
Carames, B.2
Lires-Dean, M.3
Cillero-Pastor, B.4
Ruiz-Romero, C.5
Galdo, F.6
Blanco, F.J.7
-
11
-
-
34547436716
-
TNF-induced structural joint damage is mediated by IL-1
-
10.1073/pnas.0610812104, 1913858, 17609389
-
Zwerina J, Redlich K, Polzer K, Joosten L, Kronke G, Distler J, Hess A, Pundt N, Pap T, Hoffmann O, Gasser J, Scheinecker C, Smolen JS, Berg W, Schett G. TNF-induced structural joint damage is mediated by IL-1. Proc Natl Acad Sci USA 2007, 104:11742-11747. 10.1073/pnas.0610812104, 1913858, 17609389.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11742-11747
-
-
Zwerina, J.1
Redlich, K.2
Polzer, K.3
Joosten, L.4
Kronke, G.5
Distler, J.6
Hess, A.7
Pundt, N.8
Pap, T.9
Hoffmann, O.10
Gasser, J.11
Scheinecker, C.12
Smolen, J.S.13
Berg, W.14
Schett, G.15
-
12
-
-
0024210874
-
Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes
-
10.1172/JCI113823, 442785, 3264290
-
Goldring MB, Birkhead J, Sandell LJ, Kimura T, Krane SM. Interleukin 1 suppresses expression of cartilage-specific types II and IX collagens and increases types I and III collagens in human chondrocytes. J Clin Invest 1988, 82:2026-2037. 10.1172/JCI113823, 442785, 3264290.
-
(1988)
J Clin Invest
, vol.82
, pp. 2026-2037
-
-
Goldring, M.B.1
Birkhead, J.2
Sandell, L.J.3
Kimura, T.4
Krane, S.M.5
-
13
-
-
0025359009
-
Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes
-
10.1016/0167-4889(90)90145-4, 2162214
-
Lefebvre V, Peeters-Joris C, Vaes G. Modulation by interleukin 1 and tumor necrosis factor alpha of production of collagenase, tissue inhibitor of metalloproteinases and collagen types in differentiated and dedifferentiated articular chondrocytes. Biochimica et biophysica acta 1990, 1052:366-378. 10.1016/0167-4889(90)90145-4, 2162214.
-
(1990)
Biochimica et biophysica acta
, vol.1052
, pp. 366-378
-
-
Lefebvre, V.1
Peeters-Joris, C.2
Vaes, G.3
-
14
-
-
0035955374
-
Identification of novel genes coding for small expressed RNAs
-
10.1126/science.1064921, 11679670
-
Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T. Identification of novel genes coding for small expressed RNAs. Science 2001, 294:853-858. 10.1126/science.1064921, 11679670.
-
(2001)
Science
, vol.294
, pp. 853-858
-
-
Lagos-Quintana, M.1
Rauhut, R.2
Lendeckel, W.3
Tuschl, T.4
-
15
-
-
0347444723
-
MicroRNAs: genomics, biogenesis, mechanism, and function
-
10.1016/S0092-8674(04)00045-5, 14744438
-
Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell 2004, 116:281-297. 10.1016/S0092-8674(04)00045-5, 14744438.
-
(2004)
Cell
, vol.116
, pp. 281-297
-
-
Bartel, D.P.1
-
16
-
-
0035955366
-
An extensive class of small RNAs in Caenorhabditis elegans
-
10.1126/science.1065329, 11679672
-
Lee RC, Ambros V. An extensive class of small RNAs in Caenorhabditis elegans. Science 2001, 294:862-864. 10.1126/science.1065329, 11679672.
-
(2001)
Science
, vol.294
, pp. 862-864
-
-
Lee, R.C.1
Ambros, V.2
-
17
-
-
0035955361
-
An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans
-
10.1126/science.1065062, 11679671
-
Lau NC, Lim LP, Weinstein EG, Bartel DP. An abundant class of tiny RNAs with probable regulatory roles in Caenorhabditis elegans. Science 2001, 294:858-862. 10.1126/science.1065062, 11679671.
-
(2001)
Science
, vol.294
, pp. 858-862
-
-
Lau, N.C.1
Lim, L.P.2
Weinstein, E.G.3
Bartel, D.P.4
-
18
-
-
18344369543
-
MicroRNA biogenesis: coordinated cropping and dicing
-
Kim VN. MicroRNA biogenesis: coordinated cropping and dicing. Nat Rev Mol Cell Biol 2005, 6:376-385.
-
(2005)
Nat Rev Mol Cell Biol
, vol.6
, pp. 376-385
-
-
Kim, V.N.1
-
19
-
-
77953067173
-
MicroRNA-140 plays dual roles in both cartilage development and homeostasis
-
10.1101/gad.1915510, 2878654, 20466812
-
Miyaki S, Sato T, Inoue A, Otsuki S, Ito Y, Yokoyama S, Kato Y, Takemoto F, Nakasa T, Yamashita S, Takada S, Lotz MK, Ueno-Kudo H, Asahara H. MicroRNA-140 plays dual roles in both cartilage development and homeostasis. Genes Dev 2010, 24:1173-1185. 10.1101/gad.1915510, 2878654, 20466812.
-
(2010)
Genes Dev
, vol.24
, pp. 1173-1185
-
-
Miyaki, S.1
Sato, T.2
Inoue, A.3
Otsuki, S.4
Ito, Y.5
Yokoyama, S.6
Kato, Y.7
Takemoto, F.8
Nakasa, T.9
Yamashita, S.10
Takada, S.11
Lotz, M.K.12
Ueno-Kudo, H.13
Asahara, H.14
-
20
-
-
77951743715
-
MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes
-
3139404, 20131257
-
Akhtar N, Rasheed Z, Ramamurthy S, Anbazhagan AN, Voss FR, Haqqi TM. MicroRNA-27b regulates the expression of matrix metalloproteinase 13 in human osteoarthritis chondrocytes. Arthritis Rheum 2010, 62:1361-1371. 3139404, 20131257.
-
(2010)
Arthritis Rheum
, vol.62
, pp. 1361-1371
-
-
Akhtar, N.1
Rasheed, Z.2
Ramamurthy, S.3
Anbazhagan, A.N.4
Voss, F.R.5
Haqqi, T.M.6
-
21
-
-
84870647022
-
UCSC genome browser
-
UCSC genome browser. http://genome.ucsc.edu
-
-
-
-
22
-
-
84871066143
-
TargetScan 6.2
-
TargetScan 6.2. http://www.targetscan.org
-
-
-
-
23
-
-
34748853883
-
A simple array platform for microRNA analysis and its application in mouse tissues
-
10.1261/rna.498607, 1986807, 17675362
-
Tang X, Gal J, Zhuang X, Wang W, Zhu H, Tang G. A simple array platform for microRNA analysis and its application in mouse tissues. RNA 2007, 13:1803-1822. 10.1261/rna.498607, 1986807, 17675362.
-
(2007)
RNA
, vol.13
, pp. 1803-1822
-
-
Tang, X.1
Gal, J.2
Zhuang, X.3
Wang, W.4
Zhu, H.5
Tang, G.6
-
24
-
-
84867397504
-
B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells
-
10.1038/leu.2012.95, 22469780
-
Puissegur MP, Eichner R, Quelen C, Coyaud E, Mari B, Lebrigand K, Broccardo C, Nguyen-Khac F, Bousquet M, Brousset P. B-cell regulator of immunoglobulin heavy chain transcription (Bright)/ARID3a is a direct target of the oncomir microRNA-125b in progenitor B-cells. Leukemia 2012, 26:2224-32. 10.1038/leu.2012.95, 22469780.
-
(2012)
Leukemia
, vol.26
, pp. 2224-2232
-
-
Puissegur, M.P.1
Eichner, R.2
Quelen, C.3
Coyaud, E.4
Mari, B.5
Lebrigand, K.6
Broccardo, C.7
Nguyen-Khac, F.8
Bousquet, M.9
Brousset, P.10
-
25
-
-
18044377963
-
Principles of microRNA-target recognition
-
10.1371/journal.pbio.0030085, 1043860, 15723116
-
Brennecke J, Stark A, Russell RB, Cohen SM. Principles of microRNA-target recognition. PLoS Biol 2005, 3:e85. 10.1371/journal.pbio.0030085, 1043860, 15723116.
-
(2005)
PLoS Biol
, vol.3
-
-
Brennecke, J.1
Stark, A.2
Russell, R.B.3
Cohen, S.M.4
-
26
-
-
37149053759
-
Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes
-
10.1002/art.23043, 18050214
-
Chockalingam PS, Varadarajan U, Sheldon R, Fortier E, LaVallie ER, Morris EA, Yaworsky PJ, Majumdar MK. Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes. Arthritis Rheum 2007, 56:4074-4083. 10.1002/art.23043, 18050214.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 4074-4083
-
-
Chockalingam, P.S.1
Varadarajan, U.2
Sheldon, R.3
Fortier, E.4
LaVallie, E.R.5
Morris, E.A.6
Yaworsky, P.J.7
Majumdar, M.K.8
-
27
-
-
69449103973
-
MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses
-
10.1002/art.24745, 2806094, 19714579
-
Miyaki S, Nakasa T, Otsuki S, Grogan SP, Higashiyama R, Inoue A, Kato Y, Sato T, Lotz MK, Asahara H. MicroRNA-140 is expressed in differentiated human articular chondrocytes and modulates interleukin-1 responses. Arthritis Rheum 2009, 60:2723-2730. 10.1002/art.24745, 2806094, 19714579.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 2723-2730
-
-
Miyaki, S.1
Nakasa, T.2
Otsuki, S.3
Grogan, S.P.4
Higashiyama, R.5
Inoue, A.6
Kato, Y.7
Sato, T.8
Lotz, M.K.9
Asahara, H.10
-
28
-
-
84865484629
-
MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion
-
10.1074/jbc.M112.391243, 22782903
-
Xu N, Zhang L, Meisgen F, Harada M, Heilborn J, Homey B, Grander D, Stahle M, Sonkoly E, Pivarcsi A. MicroRNA-125b down-regulates matrix metallopeptidase 13 and inhibits cutaneous squamous cell carcinoma cell proliferation, migration, and invasion. J Biol Chem 2012, 287:29899-29908. 10.1074/jbc.M112.391243, 22782903.
-
(2012)
J Biol Chem
, vol.287
, pp. 29899-29908
-
-
Xu, N.1
Zhang, L.2
Meisgen, F.3
Harada, M.4
Heilborn, J.5
Homey, B.6
Grander, D.7
Stahle, M.8
Sonkoly, E.9
Pivarcsi, A.10
-
29
-
-
84873060781
-
MicroRNA-125b inhibits tube formation of blood vessels through translational suppression of VE-cadherin
-
Muramatsu F, Kidoya H, Naito H, Sakimoto S, Takakura N. microRNA-125b inhibits tube formation of blood vessels through translational suppression of VE-cadherin. Oncogene 2012, 32:414-21.
-
(2012)
Oncogene
, vol.32
, pp. 414-421
-
-
Muramatsu, F.1
Kidoya, H.2
Naito, H.3
Sakimoto, S.4
Takakura, N.5
-
30
-
-
73249137617
-
Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development
-
10.1002/art.25002, 2832925, 19950295
-
Little CB, Barai A, Burkhardt D, Smith SM, Fosang AJ, Werb Z, Shah M, Thompson EW. Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development. Arthritis Rheum 2009, 60:3723-3733. 10.1002/art.25002, 2832925, 19950295.
-
(2009)
Arthritis Rheum
, vol.60
, pp. 3723-3733
-
-
Little, C.B.1
Barai, A.2
Burkhardt, D.3
Smith, S.M.4
Fosang, A.J.5
Werb, Z.6
Shah, M.7
Thompson, E.W.8
-
31
-
-
84863433008
-
Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis
-
10.1038/nrrheum.2012.80, 22641138
-
Mapp PI, Walsh DA. Mechanisms and targets of angiogenesis and nerve growth in osteoarthritis. Nature reviews Rheumatology 2012, 8:390-398. 10.1038/nrrheum.2012.80, 22641138.
-
(2012)
Nature reviews Rheumatology
, vol.8
, pp. 390-398
-
-
Mapp, P.I.1
Walsh, D.A.2
|