IL-6-accelerated calcification by induction of ROR2 in human adipose tissue-derived mesenchymal stem cells is STAT3 dependent

Rheumatology (United Kingdom)

Volumn 53, Issue 7, 2014, Pages 1282-1290

  Fukuyo, Shunsuke ^a   Yamaoka, Kunihiro ^a   Sonomoto, Koshiro ^a   Oshita, Koichi ^a,b   Okada, Yosuke ^a   Saito, Kazuyoshi ^a   Yoshida, Yasuhiro ^c   Kanazawa, Tamotsu ^c   Minami, Yasuhiro ^d   Tanaka, Yoshiya ^a  

^a UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^b MITSUBISHI TANABE PHARMA CORPORATION   (Japan)

^c UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

^d KOBE UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

ADSCs; Ectopic calcification; IL 6; ROR2; STAT3; WNT5A

Indexed keywords

ALIZARIN RED S; BETA CATENIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MESSENGER RNA; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR 2; SMALL INTERFERING RNA; STAT1 PROTEIN; STAT3 PROTEIN; TRANSCRIPTION FACTOR RUNX2; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; WNT10B PROTEIN; WNT3A PROTEIN; WNT5A PROTEIN; WNT7B PROTEIN;

ADIPOSE DERIVED STEM CELL; ARTICLE; BONE MINERALIZATION; CALCIFICATION; CELL DIFFERENTIATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IN VITRO STUDY; MESENCHYMAL STEM CELL; OSTEOBLAST; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SUBCUTANEOUS FAT; WESTERN BLOTTING; WNT SIGNALING PATHWAY;

ADSCS; ECTOPIC CALCIFICATION; IL-6; ROR2; STAT3; WNT5A;

ADIPOSE TISSUE; BETA CATENIN; CALCIFICATION, PHYSIOLOGIC; CELL DIFFERENTIATION; CELLS, CULTURED; CORE BINDING FACTOR ALPHA 1 SUBUNIT; HUMANS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MESENCHYMAL STROMAL CELLS; OSTEOBLASTS; PROTO-ONCOGENE PROTEINS; RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTORS; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TUMOR NECROSIS FACTOR-ALPHA; WNT PROTEINS;

EID: 84902986599     PISSN: 14620324     EISSN: 14620332     Source Type: Journal    
DOI: 10.1093/rheumatology/ket496     Document Type: Article

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