Genome-wide DNA methylation analysis in dermal fibroblasts from patients with diffuse and limited systemic sclerosis reveals common and subset-specific DNA methylation aberrancies

Annals of the Rheumatic Diseases

Volumn 74, Issue 8, 2015, Pages 1612-1620

  Altorok, Nezam ^a,b   Tsou, Pei Suen ^a   Coit, Patrick ^a   Khanna, Dinesh ^a   Sawalha, Amr H ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b MEDICAL COLLEGE OF OHIO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTEGRIN; CENTROMERE ANTIBODY; CYTOSINE; DNA DIRECTED RNA POLYMERASE III; ENZYME ANTIBODY; MYCOPHENOLATE MOFETIL; PREDNISONE; RIBONUCLEOPROTEIN ANTIBODY; TOPOISOMERASE 1 ANTIBODY; TRANSCRIPTION FACTOR RUNX1; TRANSCRIPTION FACTOR RUNX2; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

ADAM12 GENE; ADULT; AGED; ARTICLE; CLINICAL ARTICLE; COL23A1 GENE; COL4A2 GENE; CONTROLLED STUDY; CORRELATION ANALYSIS; CPG ISLAND; DIFFERENTIAL DIAGNOSIS; DIFFUSE SYSTEMIC SCLEROSIS; DNA METHYLATION; FEMALE; FOCAL ADHESION; GENE; GENE EXPRESSION; GENETIC ASSOCIATION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; HYPERMETHYLATION; HYPOMETHYLATION; ITGA9 GENE; LIMITED CUTANEOUS SYSTEMIC SCLEROSIS; MALE; MIDDLE AGED; MYO1E GENE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; RUNX1 GENE; RUNX2 GENE; RUNX3 GENE; SEROLOGY; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; SYSTEMIC SCLEROSIS; YOUNG ADULT; CYTOLOGY; DIFFUSE SCLERODERMA; EPIGENETICS; FIBROBLAST; GENOME-WIDE ASSOCIATION STUDY; LIMITED SCLERODERMA; METABOLISM; SKIN;

ADULT; AGED; DNA METHYLATION; EPIGENOMICS; FEMALE; FIBROBLASTS; GENOME-WIDE ASSOCIATION STUDY; HUMANS; MALE; MIDDLE AGED; SCLERODERMA, DIFFUSE; SCLERODERMA, LIMITED; SKIN;

EID: 84940368260     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2014-205303     Document Type: Article

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