Upregulation of ANK protein expression in joint tissue in calcium pyrophosphate dihydrate crystal deposition disease

Journal of Rheumatology

Volumn 41, Issue 1, 2014, Pages 65-74

  Uzuki, Miwa ^a   Sawai, Takashi ^a   Ryan, Lawrence M ^b   Rosenthal, Ann K ^b   Masuda, Ikuko ^b,c  

^a IWATE MEDICAL UNIVERSITY   (Japan)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

Author keywords

ANK; Calcium pyrophosphate dihydrate; Cartilage; Immunohistochemistry; In situ hybridization; Pathology

Indexed keywords

ANK PROTEIN; CALCIUM PYROPHOSPHATE; CELL PROTEIN; COLLAGEN TYPE 10; OSTEOCALCIN; OSTEOPONTIN; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

AGED; ARTHROPATHY; ARTICLE; CALCIUM PYROPHOSPHATE DIHYDRATE CRYSTAL DEPOSITION DISEASE; CARTILAGE; CARTILAGE CELL; CONTROLLED STUDY; DISEASE MARKER; FEMALE; HUMAN; HUMAN TISSUE; HYPERTROPHY; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN SITU HYBRIDIZATION; JOINT; KNEE MENISCUS; MALE; OSTEOARTHRITIS; OSTEOBLAST; OSTEOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SYNOVIOCYTE; UPREGULATION;

ANK; CALCIUM PYROPHOSPHATE DIHYDRATE; CARTILAGE; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; PATHOLOGY;

ADULT; AGED; BONE AND BONES; CARTILAGE, ARTICULAR; CHONDROCALCINOSIS; CHONDROCYTES; FEMALE; HUMANS; JOINTS; MALE; MIDDLE AGED; OSTEOARTHRITIS; PHOSPHATE TRANSPORT PROTEINS; UP-REGULATION;

EID: 84891775364     PISSN: 0315162X     EISSN: 14992752     Source Type: Journal    
DOI: 10.3899/jrheum.111476     Document Type: Article

References (33)

1. Yelin E, Callahan LF. The economic cost and social and psychological impact of musculoskeletal conditions. National Arthritis Data Work Groups. Arthritis Rheum 1995;38:1351-62.
2. Doyle DV. Tissue calcification and inflammation in osteoarthritis. J Pathol 1982;136:199-216.
3. Fuerst M, Bertrand J, Lammers L, Dreier R, Echtermeyer F, Nitschke Y, et al. Calcification of articular cartilage in human osteoarthritis. Arthritis Rheum 2009;60:2694-703.
4. Cheung HS, Ryan LM. Role of crystal deposition in matrix degradation. In: Woessner FJ, Howell DS, eds. Joint cartilage degradation: basic and clinical aspects. New York: Marcel Dekker; 1995:209-23.
5. Nalbant S, Martinez JA, Kitumnuaypong T, Clayburne G, Sieck M, Schumacher HR Jr. Synovial fluid features and their relations to osteoarthritis severity: new findings from sequential studies. Osteoarthritis Cartilage 2003;11:50-4.
6. Ishikawa K, Masuda I, Ohira T, Yokoyama M. A histologic study of calcium pyrophosphate dihydrate crystal deposition disease. J Bone Joint Surg Am 1989;71:875-86.
7. Eerola I, Salminen H, Lammi P, Lammi M, von der Mark K, Vuorio E, et al. Type X collagen, a natural component of mouse articular cartilage: association with growth, aging, and osteoarthritis. Arthritis Rheum 1998;41:1287-95.
8. Masuda I, Ishikawa K, Usuku G. A histologic and immunohistochemical study of calcium pyrophosphate dihydrate crystal deposition disease. Clin Orthop Rel Res 1991;263:272-87.
9. Rosenthal AK, Gohr CM, Uzuki M, Masuda I. Osteopontin promotes pathologic mineralization in articular cartilage. Matrix Biol 2007;26:96-105.
10. Hirose J, Ryan LM, Masuda I. Up-regulated expression of cartilage intermediate-layer protein and ANK in articular hyaline cartilage from patients with calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 2002;46:3218-29.
11. Johnson K, Terkeltaub R. Inorganic pyrophosphate (PPI) in pathologic calcification of articular cartilage. Front Biosci 2005;10:988-97.
12. Rachow JW, Ryan LM, McCarty DJ, Halverson PC. Synovial fluid inorganic pyrophosphate concentration and nucleotide pyrophosphohydrolase activity in basic calcium phosphate deposition arthropathy and Milwaukee shoulder syndrome. Arthritis Rheum 1988;31:408-13.
13. Rosenthal AK, Henry LA. Retinoic acid stimulates pyrophosphate elaboration by cartilage and chondrocytes. Calcif Tissue Int 1996;59:128-33.
14. Ho AM, Johnson MD, Kingsley DM. Role of the mouse ank gene in control of tissue calcification and arthritis. Science 2000;289:265-70.
15. Costello JC, Rosenthal AK, Kurup IV, Masuda I, Medhora M, Ryan LM. Parallel regulation of extracellular ATP and inorganic pyrophosphate: roles of growth factors, transduction modulators, and ANK. Connect Tissue Res 2011;52:139-46.
16. Williams CJ, Pendleton A, Bonavita G, Reginato AJ, Hughes AE, Peariso S, et al. Mutations in the amino terminus of ANKH in two US families with calcium pyrophosphate dihydrate crystal deposition disease. Arthritis Rheum 2003;48:2627-31.
17. Netter P, Bardin T, Bianchi A, Richette P, Loeuille D. The ANKH gene and familial calcium pyrophosphate dihydrate deposition disease. Joint Bone Spine 2004;71:365-8.
18. Ryan LM, McCarty DJ. Calcium pyrophosphate crystal deposition disease: pseudogout, articular chondrocalcinosis. In: McCarty DJ, ed. Arthritis and allied conditions: a textbook of rheumatology. 10th edition. Philadelphia: Lea & Febiger; 1985:1515-46.
19. Strehlau J, Pavlakis M, Lipman M, Shapiro M, Vasconcellos L, Harmon W, et al. Quantitative detection of immune activation transcripts as a diagnostic tool in kidney transplantation. Proc Natl Acad Sci U S A 1997;94:695-700.
20. Sanger F, Nicklen S, Coulson AR. DNA sequencing with chain terminating inhibitors. Proc Natl Acad Sci U S A 1977;74:5463-7.
21. Hayashi M, Ninomiya Y, Parsons J, Hayashi K, Olsen BR, Trelstad RL. Differential localization of mRNAs of collagen types I and II in chick fibroblasts, chondrocytes, and corneal cells by in situ hybridization using cDNA probes. J Cell Biol 1986;102:2302-9.
22. Montone KT, Brigati DJ. In situ molecular pathology: instrumentation, oligonucleotides, and viral nucleic acid detection. J Histotechnol 1994;17:195-201.
23. Felgar RE, Montone KT, Furth EE. A rapid method for detection of hepatitis C virus RNA by in situ hybridization. Mod Pathol 1996;9:696-702.
24. Sasano H, Uzuki M, Sawai T, Nagura H, Matsunaga G, Kashimoto O, et al. Aromatase in human bone tissue. J Bone Miner Res 1997;12:1416-23.
25. Uzuki M, Sasano H, Muramatsu Y, Totsune K, Oki Y, Takahashi K, et al. Urocortin in the synovial tissue of patients with rheumatoid arthritis. Clinical Science 2001;100:577-89.
26. Wang W, Xu J, Du B, Kirsch T. Role of the progressive ankylosis gene (ank) in cartilage mineralization. Mol Cell Biol 2005; 25:312-23.
27. Derfus B, Kranendonk S, Camacho N, Mandel N, Kushnaryov V, Lynch K, et al. Human osteoarthritic cartilage matrix vesicles generate both calcium pyrophosphate dihydrate and apatite in vitro. Calcif Tissue Int 1998;63:258-62.
28. Rosenthal AK, Gohr CM, Ninomiya J, Wakim BT. Proteomic analysis of articular cartilage vesicles from normal and osteoarthritic cartilage. Arthritis Rheum 2011;63:401-11.
29. Takeda S, Bonnamy JP, Owen MJ, Ducy P, Karsenty G. Continuous expression of Cbfa1 in nonhypertrophic chondrocytes uncovers its ability to induce hypertrophic chondrocyte differentiation and partially rescues Cbfa1-deficient mice. Genes Dev 2001;15:467-81.
30. Kirsch T, Kim HJ, Winkles JA. Progressive ankylosis gene (ank) regulates osteoblast differentiation. Cells Tissues Organs 2009;189:158-62.
31. Giachelli CM. The emerging role of phosphate in vascular calcification. Kidney Int 2009;75:890-7.
32. Cailotto F, Bianchi A, Sebillaud S, Venkatesan N, Moulin D, Jouzeau JY, et al. Inorganic pyrophosphate generation by transforming growth factor-beta-1 is mainly dependent on ANK induction by Ras/Raf-1/extracellular signal-regulated kinase pathways in chondrocytes. Arthritis Res Ther 2007;9:R122.
33. Johnson K, Terkeltaub R. Upregulated ank expression in osteoarthritis can promote both chondrocyte MMP-13 expression and calcification via chondrocyte extracellular PPi excess. Osteoarthritis Cartilage 2004;12:321-35.