-
1
-
-
33846882630
-
Molecular pathogenesis of osteosarcoma
-
Kansara, M., and Thomas, D. M. (2007) Molecular pathogenesis of osteosarcoma. DNA Cell Biol. 26,1-18
-
(2007)
DNA Cell Biol.
, vol.26
, pp. 1-18
-
-
Kansara, M.1
Thomas, D.M.2
-
2
-
-
77951116026
-
Regulation of gene expression in osteoblasts
-
Jensen, E. D., Gopalakrishnan, R., and Westendorf, J. J. (2010) Regulation of gene expression in osteoblasts. Biofactors 36, 25-32
-
(2010)
Biofactors
, vol.36
, pp. 25-32
-
-
Jensen, E.D.1
Gopalakrishnan, R.2
Westendorf, J.J.3
-
3
-
-
42749092987
-
Transcription factors controlling osteoblastogenesis
-
Marie, P. J. (2008) Transcription factors controlling osteoblastogenesis. Arch. Biochem. Biophys. 473, 98 -105
-
(2008)
Arch. Biochem. Biophys.
, vol.473
, pp. 98-105
-
-
Marie, P.J.1
-
4
-
-
79251553733
-
The role of RUNX2 in osteosarcoma oncogenesis
-
Martin, J. W., Zielenska, M., Stein, G. S., van Wijnen, A. J., and Squire, J. A. (2011) The role of RUNX2 in osteosarcoma oncogenesis. Sarcoma 2011, 282745
-
(2011)
Sarcoma
, vol.2011
, pp. 282745
-
-
Martin, J.W.1
Zielenska, M.2
Stein, G.S.3
Van Wijnen, A.J.4
Squire, J.A.5
-
6
-
-
0026318628
-
Molecular genetic considerations in osteosarcoma
-
Hansen, M. F. (1991) Molecular genetic considerations in osteosarcoma. Clin. Orthop. Relat. Res. 270, 237-246
-
(1991)
Clin. Orthop. Relat. Res.
, vol.270
, pp. 237-246
-
-
Hansen, M.F.1
-
7
-
-
50149110590
-
Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage
-
Berman, S. D., Calo, E., Landman, A. S., Danielian, P. S., Miller, E. S., West, J. C., Fonhoue, B. D., Caron, A., Bronson, R., Bouxsein, M. L., Mukherjee, S., and Lees, J. A. (2008) Metastatic osteosarcoma induced by inactivation of Rb and p53 in the osteoblast lineage. Proc. Natl. Acad. Sci. U.S.A. 105, 11851-11856
-
(2008)
Proc. Natl. Acad. Sci. U.S.A.
, vol.105
, pp. 11851-11856
-
-
Berman, S.D.1
Calo, E.2
Landman, A.S.3
Danielian, P.S.4
Miller, E.S.5
West, J.C.6
Fonhoue, B.D.7
Caron, A.8
Bronson, R.9
Bouxsein, M.L.10
Mukherjee, S.11
Lees, J.A.12
-
8
-
-
45349086509
-
Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease
-
Walkley, C. R., Qudsi, R., Sankaran, V. G., Perry, J. A., Gostissa, M., Roth, S. I., Rodda, S. J., Snay, E., Dunning, P., Fahey, F. H., Alt, F. W., McMahon, A. P., and Orkin, S. H. (2008) Conditional mouse osteosarcoma, dependent on p53 loss and potentiated by loss of Rb, mimics the human disease. Genes Dev. 22, 1662-1676
-
(2008)
Genes Dev.
, vol.22
, pp. 1662-1676
-
-
Walkley, C.R.1
Qudsi, R.2
Sankaran, V.G.3
Perry, J.A.4
Gostissa, M.5
Roth, S.I.6
Rodda, S.J.7
Snay, E.8
Dunning, P.9
Fahey, F.H.10
Alt, F.W.11
McMahon, A.P.12
Orkin, S.H.13
-
9
-
-
33644879150
-
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling
-
Lengner, C. J., Steinman, H. A., Gagnon, J., Smith, T. W., Henderson, J. E., Kream, B. E., Stein, G. S., Lian, J. B., and Jones, S. N. (2006) Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling. J. Cell Biol. 172, 909-921
-
(2006)
J. Cell Biol.
, vol.172
, pp. 909-921
-
-
Lengner, C.J.1
Steinman, H.A.2
Gagnon, J.3
Smith, T.W.4
Henderson, J.E.5
Kream, B.E.6
Stein, G.S.7
Lian, J.B.8
Jones, S.N.9
-
10
-
-
33845987376
-
Networks and hubs for the transcriptional control of osteoblastogenesis
-
Lian, J. B., Stein, G. S., Javed, A., van Wijnen, A. J., Stein, J. L., Montecino, M., Hassan, M. Q., Gaur, T., Lengner, C. J., and Young, D. W. (2006) Networks and hubs for the transcriptional control of osteoblastogenesis. Rev. Endocr. Metab. Disord. 7,1-16
-
(2006)
Rev. Endocr. Metab. Disord.
, vol.7
, pp. 1-16
-
-
Lian, J.B.1
Stein, G.S.2
Javed, A.3
Van Wijnen, A.J.4
Stein, J.L.5
Montecino, M.6
Hassan, M.Q.7
Gaur, T.8
Lengner, C.J.9
Young, D.W.10
-
11
-
-
20144371011
-
The bone-specific expression of RUNX2 oscillates during the cell cycle to support a G1-related anti-proliferative function in osteoblasts
-
Galindo, M., Pratap, J., Young, D. W., Hovhannisyan, H., Im, H. J., Choi, J. Y., Lian, J. B., Stein, J. L., Stein, G. S., and van Wijnen, A. J. (2005) The bone-specific expression of RUNX2 oscillates during the cell cycle to support a G1-related anti-proliferative function in osteoblasts. J. Biol. Chem. 280, 20274-20285
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 20274-20285
-
-
Galindo, M.1
Pratap, J.2
Young, D.W.3
Hovhannisyan, H.4
Im, H.J.5
Choi, J.Y.6
Lian, J.B.7
Stein, J.L.8
Stein, G.S.9
Van Wijnen, A.J.10
-
12
-
-
56649109716
-
Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma
-
Nathan, S. S., Pereira, B. P., Zhou, Y. F., Gupta, A., Dombrowski, C., Soong, R., Pho, R. W., Stein, G. S., Salto-Tellez, M., Cool, S. M., and van Wijnen, A. J. (2009) Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma. Mol. Biol. Rep. 36,153-158
-
(2009)
Mol. Biol. Rep.
, vol.36
, pp. 153-158
-
-
Nathan, S.S.1
Pereira, B.P.2
Zhou, Y.F.3
Gupta, A.4
Dombrowski, C.5
Soong, R.6
Pho, R.W.7
Stein, G.S.8
Salto-Tellez, M.9
Cool, S.M.10
Van Wijnen, A.J.11
-
13
-
-
0141705433
-
Cell growth regulatory role of Runx2 during proliferative expansion of pre-osteoblasts
-
Pratap, J., Galindo, M., Zaidi, S. K., Vradii, D., Bhat, B. M., Robinson, J. A., Choi, J.-Y., Komori, T., Stein, J. L., Lian, J. B., Stein, G. S., and van Wijnen, A. J. (2003) Cell growth regulatory role of Runx2 during proliferative expansion of pre-osteoblasts. Cancer Res. 63, 5357-5362
-
(2003)
Cancer Res.
, vol.63
, pp. 5357-5362
-
-
Pratap, J.1
Galindo, M.2
Zaidi, S.K.3
Vradii, D.4
Bhat, B.M.5
Robinson, J.A.6
Choi, J.-Y.7
Komori, T.8
Stein, J.L.9
Lian, J.B.10
Stein, G.S.11
Van Wijnen, A.J.12
-
14
-
-
55549120557
-
Runx2 regulates G-protein coupled signaling pathways to control growth of osteoblast progenitors
-
Teplyuk, N. M., Galindo, M., Teplyuk, V. I., Pratap, J., Young, D. W., Lapointe, D., Javed, A., Stein, J. L., Lian, J. B., Stein, G. S., and van Wijnen, A. J. (2008) Runx2 regulates G-protein coupled signaling pathways to control growth of osteoblast progenitors. J. Biol. Chem. 283,27585-27597
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 27585-27597
-
-
Teplyuk, N.M.1
Galindo, M.2
Teplyuk, V.I.3
Pratap, J.4
Young, D.W.5
Lapointe, D.6
Javed, A.7
Stein, J.L.8
Lian, J.B.9
Stein, G.S.10
Van Wijnen, A.J.11
-
15
-
-
77953426747
-
Analysis of segmental duplications, mouse genome synteny, and recurrent cancer-associated amplicons in human chromosome 6p21-p12
-
Martin, J. W., Yoshimoto, M., Ludkovski, O., Thorner, P. S., Zielenska, M., Squire, J. A., and Nuin, P. A. (2010) Analysis of segmental duplications, mouse genome synteny, and recurrent cancer-associated amplicons in human chromosome 6p21-p12. Cytogenet. Genome Res. 128,199-213
-
(2010)
Cytogenet. Genome Res.
, vol.128
, pp. 199-213
-
-
Martin, J.W.1
Yoshimoto, M.2
Ludkovski, O.3
Thorner, P.S.4
Zielenska, M.5
Squire, J.A.6
Nuin, P.A.7
-
16
-
-
70449727683
-
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1)
-
Pereira, B. P., Zhou, Y., Gupta, A., Leong, D. T., Aung, K. Z., Ling, L., Pho, R. W., Galindo, M., Salto-Tellez, M., Stein, G. S., Cool, S. M., van Wijnen, A. J., and Nathan, S. S. (2009) Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1). J. Cell Physiol. 221, 778-788
-
(2009)
J. Cell Physiol.
, vol.221
, pp. 778-788
-
-
Pereira, B.P.1
Zhou, Y.2
Gupta, A.3
Leong, D.T.4
Aung, K.Z.5
Ling, L.6
Pho, R.W.7
Galindo, M.8
Salto-Tellez, M.9
Stein, G.S.10
Cool, S.M.11
Van Wijnen, A.J.12
Nathan, S.S.13
-
17
-
-
70449724816
-
Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbf in osteosarcoma cells
-
San Martin, I. A., Varela, N., Gaete, M., Villegas, K., Osorio, M., Tapia, J. C., Antonelli, M., Mancilla, E. E., Pereira, B. P., Nathan, S. S., Lian, J. B., Stein, J. L., Stein, G. S., van Wijnen, A. J., and Galindo, M. (2009) Impaired cell cycle regulation of the osteoblast-related heterodimeric transcription factor Runx2-Cbf in osteosarcoma cells. J. Cell Physiol. 221, 560-571
-
(2009)
J. Cell Physiol.
, vol.221
, pp. 560-571
-
-
San Martin, I.A.1
Varela, N.2
Gaete, M.3
Villegas, K.4
Osorio, M.5
Tapia, J.C.6
Antonelli, M.7
Mancilla, E.E.8
Pereira, B.P.9
Nathan, S.S.10
Lian, J.B.11
Stein, J.L.12
Stein, G.S.13
Van Wijnen, A.J.14
Galindo, M.15
-
18
-
-
78650307699
-
Metastatic bone disease. Role of transcription factors and future targets
-
Pratap, J., Lian, J. B., and Stein, G. S. (2011) Metastatic bone disease. Role of transcription factors and future targets. Bone 48, 30-36
-
(2011)
Bone
, vol.48
, pp. 30-36
-
-
Pratap, J.1
Lian, J.B.2
Stein, G.S.3
-
19
-
-
29944437296
-
P53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent oste-oclastogenesis, and bone remodeling
-
Wang, X., Kua, H. Y., Hu, Y., Guo, K., Zeng, Q., Wu, Q., Ng, H. H., Karsenty, G., de Crombrugghe, B., Yeh, J., and Li, B. (2006) p53 functions as a negative regulator of osteoblastogenesis, osteoblast-dependent oste-oclastogenesis, and bone remodeling. J. Cell Biol. 172, 115-125
-
(2006)
J. Cell Biol.
, vol.172
, pp. 115-125
-
-
Wang, X.1
Kua, H.Y.2
Hu, Y.3
Guo, K.4
Zeng, Q.5
Wu, Q.6
Ng, H.H.7
Karsenty, G.8
De Crombrugghe, B.9
Yeh, J.10
Li, B.11
-
20
-
-
0036840499
-
Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/ WAF1) promoter
-
Westendorf, J. J., Zaidi, S. K., Cascino, J. E., Kahler, R., van Wijnen, A. J., Lian, J. B., Yoshida, M., Stein, G. S., and Li, X. (2002) Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/ WAF1) promoter. Mol. Cell. Biol. 22, 7982-7992
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 7982-7992
-
-
Westendorf, J.J.1
Zaidi, S.K.2
Cascino, J.E.3
Kahler, R.4
Van Wijnen, A.J.5
Lian, J.B.6
Yoshida, M.7
Stein, G.S.8
Li, X.9
-
21
-
-
68749118305
-
Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer
-
Das, K., Leong, D. T., Gupta, A., Shen, L., Putti, T., Stein, G. S., van Wijnen, A. J., and Salto-Tellez, M. (2009) Positive association between nuclear Runx2 and oestrogen-progesterone receptor gene expression characterises a biological subtype of breast cancer. Eur. J. Cancer 45, 2239-2248
-
(2009)
Eur. J. Cancer
, vol.45
, pp. 2239-2248
-
-
Das, K.1
Leong, D.T.2
Gupta, A.3
Shen, L.4
Putti, T.5
Stein, G.S.6
Van Wijnen, A.J.7
Salto-Tellez, M.8
-
22
-
-
46749139206
-
TRARESA
-
Das, K., Mohd Omar, M. F., Ong, C. W., Bin Abdul Rashid, S., Peh, B. K., Putti, T. C., Tan, P. H., Chia, K. S., Teh, M., Shah, N., Soong, R., and Salto-Tellez, M. (2008) TRARESA. A tissue microarray-based hospital system for biomarker validation and discovery. Pathology 40, 441- 449
-
(2008)
A Tissue Microarray-based Hospital System for Biomarker Validation and Discovery. Pathology
, vol.40
, pp. 441-449
-
-
Das, K.1
Mohd Omar, M.F.2
Ong, C.W.3
Bin Abdul Rashid, S.4
Peh, B.K.5
Putti, T.C.6
Tan, P.H.7
Chia, K.S.8
Teh, M.9
Shah, N.10
Soong, R.11
Salto-Tellez, M.12
-
23
-
-
77949631150
-
Computer-assisted pathological immunohistochemistry scoring is more time-effective than conventional scoring, but provides no analytical advantage
-
Ong, C. W., Kim, L. G., Kong, H. H., Low, L. Y., Wang, T. T., Supriya, S., Kathiresan, M., Soong, R., and Salto-Tellez, M. (2010) Computer-assisted pathological immunohistochemistry scoring is more time-effective than conventional scoring, but provides no analytical advantage. Histopathol-ogy 56, 523-529
-
(2010)
Histopathol-ogy
, vol.56
, pp. 523-529
-
-
Ong, C.W.1
Kim, L.G.2
Kong, H.H.3
Low, L.Y.4
Wang, T.T.5
Supriya, S.6
Kathiresan, M.7
Soong, R.8
Salto-Tellez, M.9
-
24
-
-
70350231597
-
Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination
-
Chi, X. Z., Kim, J., Lee, Y. H., Lee, J. W., Lee, K. S., Wee, H., Kim, W. J., Park, W. Y., Oh, B. C., Stein, G. S., Ito, Y., van Wijnen, A. J., Bae, S. C. (2009) Runt-related transcription factor RUNX3 is a target of MDM2-mediated ubiquitination. Cancer Res. 69, 8111-8119
-
(2009)
Cancer Res.
, vol.69
, pp. 8111-8119
-
-
Chi, X.Z.1
Kim, J.2
Lee, Y.H.3
Lee, J.W.4
Lee, K.S.5
Wee, H.6
Kim, W.J.7
Park, W.Y.8
Oh, B.C.9
Stein, G.S.10
Ito, Y.11
Van Wijnen, A.J.12
Bae, S.C.13
-
25
-
-
0035902565
-
Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development
-
Choi, J.-Y., Pratap, J., Javed, A., Zaidi, S. K., Xing, L., Balint, E., Dalamangas, S., Boyce, B., van Wijnen, A. J., Lian, J. B., Stein, J. L., Jones, S. N., and Stein, G. S. (2001) Subnuclear targeting of Runx/Cbfa/AML factors is essential for tissue-specific differentiation during embryonic development. Proc. Natl. Acad. Sci. U.S.A. 98, 8650- 8655
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 8650-8655
-
-
Choi, J.-Y.1
Pratap, J.2
Javed, A.3
Zaidi, S.K.4
Xing, L.5
Balint, E.6
Dalamangas, S.7
Boyce, B.8
Van Wijnen, A.J.9
Lian, J.B.10
Stein, J.L.11
Jones, S.N.12
Stein, G.S.13
-
26
-
-
1842457741
-
Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription
-
Zaidi, S. K., Sullivan, A. J., Medina, R., Ito, Y., van Wijnen, A. J., Stein, J. L., Lian, J. B., and Stein, G. S. (2004) Tyrosine phosphorylation controls Runx2-mediated subnuclear targeting of YAP to repress transcription. EMBO J. 23, 790-799
-
(2004)
EMBO J
, vol.23
, pp. 790-799
-
-
Zaidi, S.K.1
Sullivan, A.J.2
Medina, R.3
Ito, Y.4
Van Wijnen, A.J.5
Stein, J.L.6
Lian, J.B.7
Stein, G.S.8
-
27
-
-
59149094516
-
Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats)
-
Zhang, Y., Hassan, M. Q., Xie, R. L., Hawse, J. R., Spelsberg, T. C., Monte-cino, M., Stein, J. L., Lian, J. B., van Wijnen, A. J., and Stein, G. S. (2009) Co-stimulation of the bone-related Runx2 P1 promoter in mesenchymal cells by SP1 and ETS transcription factors at polymorphic purine-rich DNA sequences (Y-repeats). J. Biol. Chem. 284, 3125-3135
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3125-3135
-
-
Zhang, Y.1
Hassan, M.Q.2
Xie, R.L.3
Hawse, J.R.4
Spelsberg, T.C.5
Monte-Cino, M.6
Stein, J.L.7
Lian, J.B.8
Van Wijnen, A.J.9
Stein, G.S.10
-
28
-
-
33846489816
-
Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2
-
Young, D. W., Hassan, M. Q., Pratap, J., Galindo, M., Zaidi, S. K., Lee, S. H., Yang, X., Xie, R., Javed, A., Underwood, J. M., Furcinitti, P., Imbalzano, A. N., Penman, S., Nickerson, J. A., Montecino, M. A., Lian, J. B., Stein, J. L., van Wijnen, A. J., and Stein, G. S. (2007) Mitotic occupancy and lineage-specific transcriptional control of rRNA genes by Runx2. Nature 445, 442-446
-
(2007)
Nature
, vol.445
, pp. 442-446
-
-
Young, D.W.1
Hassan, M.Q.2
Pratap, J.3
Galindo, M.4
Zaidi, S.K.5
Lee, S.H.6
Yang, X.7
Xie, R.8
Javed, A.9
Underwood, J.M.10
Furcinitti, P.11
Imbalzano, A.N.12
Penman, S.13
Nickerson, J.A.14
Montecino, M.A.15
Lian, J.B.16
Stein, J.L.17
Van Wijnen, A.J.18
Stein, G.S.19
-
29
-
-
10344237022
-
Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma
-
Thomas, D. M., Johnson, S. A., Sims, N. A., Trivett, M. K., Slavin, J. L., Rubin, B. P., Waring, P., McArthur, G. A., Walkley, C. R., Holloway, A. J., Diyagama, D., Grim, J. E., Clurman, B. E., Bowtell, D. D., Lee, J. S., Gutierrez, G. M., Piscopo, D. M., Carty, S. A., and Hinds, P. W. (2004) Terminal osteoblast differentiation, mediated by runx2 and p27KIP1, is disrupted in osteosarcoma. J. Cell Biol. 167, 925-934
-
(2004)
J. Cell Biol.
, vol.167
, pp. 925-934
-
-
Thomas, D.M.1
Johnson, S.A.2
Sims, N.A.3
Trivett, M.K.4
Slavin, J.L.5
Rubin, B.P.6
Waring, P.7
McArthur, G.A.8
Walkley, C.R.9
Holloway, A.J.10
Diyagama, D.11
Grim, J.E.12
Clurman, B.E.13
Bowtell, D.D.14
Lee, J.S.15
Gutierrez, G.M.16
Piscopo, D.M.17
Carty, S.A.18
Hinds, P.W.19
-
30
-
-
77952065237
-
Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy
-
Sadikovic, B., Thorner, P., Chilton-Macneill, S., Martin, J. W., Cervigne, N. K., Squire, J., and Zielenska, M. (2010) Expression analysis of genes associated with human osteosarcoma tumors shows correlation of RUNX2 overexpression with poor response to chemotherapy. BMC Cancer 10, 202
-
(2010)
BMC Cancer
, vol.10
, pp. 202
-
-
Sadikovic, B.1
Thorner, P.2
Chilton-Macneill, S.3
Martin, J.W.4
Cervigne, N.K.5
Squire, J.6
Zielenska, M.7
-
31
-
-
0032169516
-
The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2
-
Stott, F. J., Bates, S., James, M. C., McConnell, B. B., Starborg, M., Brookes, S., Palmero, I., Ryan, K., Hara, E., Vousden, K. H., and Peters, G. (1998) The alternative product from the human CDKN2A locus, p14(ARF), participates in a regulatory feedback loop with p53 and MDM2. EMBO J. 17, 5001-5014
-
(1998)
EMBO J
, vol.17
, pp. 5001-5014
-
-
Stott, F.J.1
Bates, S.2
James, M.C.3
McConnell, B.B.4
Starborg, M.5
Brookes, S.6
Palmero, I.7
Ryan, K.8
Hara, E.9
Vousden, K.H.10
Peters, G.11
-
32
-
-
10744221485
-
In vivo activation ofthe p53 pathwaybysmall-molecule antagonists of MDM2
-
Vassilev, L. T., Vu, B. T., Graves, B., Carvajal, D., Podlaski, F., Filipovic, Z., Kong, N., Kammlott, U., Lukacs, C., Klein, C., Fotouhi, N., and Liu, E. A. (2004) In vivo activation ofthe p53 pathwaybysmall-molecule antagonists of MDM2. Science 303, 844- 848
-
(2004)
Science
, vol.303
, pp. 844-848
-
-
Vassilev, L.T.1
Vu, B.T.2
Graves, B.3
Carvajal, D.4
Podlaski, F.5
Filipovic, Z.6
Kong, N.7
Kammlott, U.8
Lukacs, C.9
Klein, C.10
Fotouhi, N.11
Liu, E.A.12
-
33
-
-
84859386766
-
MiRNA signatures associate with pathogenesis and progression of osteosarcoma
-
Jones, K. B., Salah, Z., Del Mare, S., Galasso, M., Gaudio, E., Nuovo, G. J., Lovat, F., LeBlanc, K., Palatini, J., Randall, R. L., Volinia, S., Stein, G. S., Croce, C. M., Lian, J. B., Aqeilan, R. I. (2012) miRNA signatures associate with pathogenesis and progression of osteosarcoma. Cancer Res. 72, 1865-1877
-
(2012)
Cancer Res.
, vol.72
, pp. 1865-1877
-
-
Jones, K.B.1
Salah, Z.2
Del Mare, S.3
Galasso, M.4
Gaudio, E.5
Nuovo, G.J.6
Lovat, F.7
Leblanc, K.8
Palatini, J.9
Randall, R.L.10
Volinia, S.11
Stein, G.S.12
Croce, C.M.13
Lian, J.B.14
Aqeilan, R.I.15
-
34
-
-
79960015376
-
A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2
-
Zhang, Y., Xie, R. L., Croce, C. M., Stein, J. L., Lian, J. B., van Wijnen, A. J., and Stein, G. S. (2011) A program of microRNAs controls osteogenic lineage progression by targeting transcription factor Runx2. Proc. Natl. Acad. Sci. U.S.A. 108, 9863-9868
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
, pp. 9863-9868
-
-
Zhang, Y.1
Xie, R.L.2
Croce, C.M.3
Stein, J.L.4
Lian, J.B.5
Van Wijnen, A.J.6
Stein, G.S.7
-
35
-
-
34548803950
-
MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth
-
Corney, D. C., Flesken-Nikitin, A., Godwin, A. K., Wang, W., and Nikitin, A. Y. (2007) MicroRNA-34b and MicroRNA-34c are targets of p53 and cooperate in control of cell proliferation and adhesion-independent growth. Cancer Res. 67, 8433- 8438
-
(2007)
Cancer Res.
, vol.67
, pp. 8433-8438
-
-
Corney, D.C.1
Flesken-Nikitin, A.2
Godwin, A.K.3
Wang, W.4
Nikitin, A.Y.5
-
36
-
-
34250851115
-
A microRNA component of the p53 tumour suppressor network
-
He, L., He, X., Lim, L. P., de Stanchina, E., Xuan, Z., Liang, Y., Xue, W., Zender, L., Magnus, J., Ridzon, D., Jackson, A. L., Linsley, P. S., Chen, C., Lowe, S. W., Cleary, M. A., and Hannon, G. J. (2007) A microRNA component of the p53 tumour suppressor network. Nature 447, 1130-1134
-
(2007)
Nature
, vol.447
, pp. 1130-1134
-
-
He, L.1
He, X.2
Lim, L.P.3
De Stanchina, E.4
Xuan, Z.5
Liang, Y.6
Xue, W.7
Zender, L.8
Magnus, J.9
Ridzon, D.10
Jackson, A.L.11
Linsley, P.S.12
Chen, C.13
Lowe, S.W.14
Cleary, M.A.15
Hannon, G.J.16
-
37
-
-
44849116896
-
Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apo-ptosis
-
Eliseev, R. A., Dong, Y. F., Sampson, E., Zuscik, M. J., Schwarz, E. M., O'Keefe, R. J., Rosier, R. N., and Drissi M. H. (2008) Runx2-mediated activation of the Bax gene increases osteosarcoma cell sensitivity to apo-ptosis. Oncogene 27, 3605-3614
-
(2008)
Oncogene
, vol.27
, pp. 3605-3614
-
-
Eliseev, R.A.1
Dong, Y.F.2
Sampson, E.3
Zuscik, M.J.4
Schwarz, E.M.5
O'Keefe, R.J.6
Rosier, R.N.7
Drissi, M.H.8
-
38
-
-
84863139254
-
Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility
-
van der Deen, M., Akech, J., Lapointe, D., Gupta, S., Young, D. W., Mon-tecino, M. A., Galindo, M., Lian, J. B., Stein, J. L., Stein, G. S., and van Wijnen, A. J. (2012) Genomic promoter occupancy of runt-related transcription factor RUNX2 in Osteosarcoma cells identifies genes involved in cell adhesion and motility. J.Biol. Chem. 287, 4503-4517
-
(2012)
J.Biol. Chem.
, vol.287
, pp. 4503-4517
-
-
Van Der Deen, M.1
Akech, J.2
Lapointe, D.3
Gupta, S.4
Young, D.W.5
Mon-Tecino, M.A.6
Galindo, M.7
Lian, J.B.8
Stein, J.L.9
Stein, G.S.10
Van Wijnen, A.J.11
-
39
-
-
0030684749
-
Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts
-
Komori, T., Yagi, H., Nomura, S., Yamaguchi, A., Sasaki, K., Deguchi, K., Shimizu, Y., Bronson, R. T., Gao, Y.-H., Inada, M., Sato, M., Okamoto, R., Kitamura, Y., Yoshiki, S., and Kishimoto, T. (1997) Targeted disruption of Cbfa1 results in a complete lack of bone formation owing to maturational arrest of osteoblasts. Cell 89, 755-764
-
(1997)
Cell
, vol.89
, pp. 755-764
-
-
Komori, T.1
Yagi, H.2
Nomura, S.3
Yamaguchi, A.4
Sasaki, K.5
Deguchi, K.6
Shimizu, Y.7
Bronson, R.T.8
Gao, Y.-H.9
Inada, M.10
Sato, M.11
Okamoto, R.12
Kitamura, Y.13
Yoshiki, S.14
Kishimoto, T.15
-
40
-
-
80051924950
-
Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation
-
Liu, J. C., Lengner, C. J., Gaur, T., Lou, Y., Hussain, S., Jones, M. D., Bo-rodic, B., Colby, J. L., Steinman, H. A., van Wijnen, A. J., Stein, J. L., Jones, S. N., Stein, G. S., and Lian, J. B. (2011) Runx2 protein expression utilizes the Runx2 P1 promoter to establish osteoprogenitor cell number for normal bone formation. J.Biol. Chem. 286, 30057-30070
-
(2011)
J.Biol. Chem.
, vol.286
, pp. 30057-30070
-
-
Liu, J.C.1
Lengner, C.J.2
Gaur, T.3
Lou, Y.4
Hussain, S.5
Jones, M.D.6
Bo-Rodic, B.7
Colby, J.L.8
Steinman, H.A.9
Van Wijnen, A.J.10
Stein, J.L.11
Jones, S.N.12
Stein, G.S.13
Lian, J.B.14
-
41
-
-
58749111473
-
A Runx2 threshold for the cleidocranial dysplasia phenotype
-
Lou, Y., Javed, A., Hussain, S., Colby, J., Frederick, D., Pratap, J., Xie, R., Gaur, T., van Wijnen, A. J., Jones, S. N., Stein, G. S., Lian, J. B., and Stein, J. L. (2009) A Runx2 threshold for the cleidocranial dysplasia phenotype. Hum. Mol. Genet. 18, 556-568
-
(2009)
Hum. Mol. Genet.
, vol.18
, pp. 556-568
-
-
Lou, Y.1
Javed, A.2
Hussain, S.3
Colby, J.4
Frederick, D.5
Pratap, J.6
Xie, R.7
Gaur, T.8
Van Wijnen, A.J.9
Jones, S.N.10
Stein, G.S.11
Lian, J.B.12
Stein, J.L.13
-
42
-
-
0036900947
-
Core-binding factor β interacts with Runx2 and is required for skeletal development
-
Yoshida, C. A., Furuichi, T., Fujita, T., Fukuyama, R., Kanatani, N., Ko-bayashi, S., Satake, M., Takada, K., and Komori, T. (2002) Core-binding factor β interacts with Runx2 and is required for skeletal development. Nat. Genet. 32, 633-638
-
(2002)
Nat. Genet.
, vol.32
, pp. 633-638
-
-
Yoshida, C.A.1
Furuichi, T.2
Fujita, T.3
Fukuyama, R.4
Kanatani, N.5
Ko-Bayashi, S.6
Satake, M.7
Takada, K.8
Komori, T.9
-
43
-
-
11144354938
-
Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
-
Yoshida, C. A., Yamamoto, H., Fujita, T., Furuichi, T., Ito, K., Inoue, K., Yamana, K., Zanma, A., Takada, K., Ito, Y., and Komori, T. (2004) Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. Genes Dev. 18, 952-963
-
(2004)
Genes Dev.
, vol.18
, pp. 952-963
-
-
Yoshida, C.A.1
Yamamoto, H.2
Fujita, T.3
Furuichi, T.4
Ito, K.5
Inoue, K.6
Yamana, K.7
Zanma, A.8
Takada, K.9
Ito, Y.10
Komori, T.11
-
44
-
-
65249167488
-
Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates os-teosarcomagenesis in mice
-
Kansara, M., Tsang, M., Kodjabachian, L., Sims, N. A., Trivett, M. K., Ehrich, M., Dobrovic, A., Slavin, J., Choong, P. F., Simmons, P. J., Dawid, I. B., and Thomas, D. M. (2009) Wnt inhibitory factor 1 is epigenetically silenced in human osteosarcoma, and targeted disruption accelerates os-teosarcomagenesis in mice. J. Clin. Invest. 119, 837-851
-
(2009)
J. Clin. Invest.
, vol.119
, pp. 837-851
-
-
Kansara, M.1
Tsang, M.2
Kodjabachian, L.3
Sims, N.A.4
Trivett, M.K.5
Ehrich, M.6
Dobrovic, A.7
Slavin, J.8
Choong, P.F.9
Simmons, P.J.10
Dawid, I.B.11
Thomas, D.M.12
-
45
-
-
84862624955
-
MiR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2
-
Wei, J., Shi, Y., Zheng, L., Zhou, B., Inose, H., Wang, J., Guo, X. E., Gross-chedl, R., and Karsenty, G. (2012) miR-34s inhibit osteoblast proliferation and differentiation in the mouse by targeting SATB2. J. Cell Biol. 197, 509-521
-
(2012)
J. Cell Biol.
, vol.197
, pp. 509-521
-
-
Wei, J.1
Shi, Y.2
Zheng, L.3
Zhou, B.4
Inose, H.5
Wang, J.6
Guo, X.E.7
Gross-Chedl, R.8
Karsenty, G.9
-
46
-
-
38049155882
-
Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential
-
Zaidi, S. K., Pande, S., Pratap, J., Gaur, T., Grigoriu, S., Ali, S. A., Stein, J. L., Lian, J. B., van Wijnen, A. J., and Stein, G. S. (2007) Runx2 deficiency and defective subnuclear targeting bypass senescence to promote immortalization and tumorigenic potential. Proc. Natl. Acad. Sci. U.S.A. 104, 19861-19866
-
(2007)
Proc. Natl. Acad. Sci. U.S.A.
, vol.104
, pp. 19861-19866
-
-
Zaidi, S.K.1
Pande, S.2
Pratap, J.3
Gaur, T.4
Grigoriu, S.5
Ali, S.A.6
Stein, J.L.7
Lian, J.B.8
Van Wijnen, A.J.9
Stein, G.S.10
|