MiR-29c-3p promotes senescence of human mesenchymal stem cells by targeting CNOT6 through p53-p21 and p16-pRB pathways

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1863, Issue 4, 2016, Pages 520-532

  Shang, Jin ^a   Yao, Yuan ^a   Fan, Xin ^a   Shangguan, Lei ^a   Li, Jie ^a   Liu, Huan ^a   Zhou, Yue ^a  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Mesenchymal stem cell; MicroRNA; Replicative senescence; Tissue engineering

Indexed keywords

BETA GALACTOSIDASE; BIOLOGICAL MARKER; MICRORNA; MICRORNA 29C 3P; PROTEIN P16; PROTEIN P21; PROTEIN P53; RETINOBLASTOMA PROTEIN; UNCLASSIFIED DRUG; CDKN1A PROTEIN, HUMAN; CNOT6 PROTEIN, HUMAN; CYCLIN DEPENDENT KINASE INHIBITOR 1A; EXORIBONUCLEASE; MIRN29 MICRORNA, HUMAN; P16 PROTEIN, HUMAN; TUMOR PROTEIN;

ARTICLE; BONE DEVELOPMENT; CELL DIFFERENTIATION; CELL PROLIFERATION; CNOT6 GENE; CONTROLLED STUDY; DOWN REGULATION; GENE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; LUCIFERASE ASSAY; MESENCHYMAL STEM CELL; MICROARRAY ANALYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; TRANSCRIPTION REGULATION; UPREGULATION; WESTERN BLOTTING; CELL AGING; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P21; EXORIBONUCLEASES; GENE EXPRESSION REGULATION; HUMANS; MESENCHYMAL STROMAL CELLS; MICRORNAS; NEOPLASM PROTEINS; RETINOBLASTOMA PROTEIN; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84955444131     PISSN: 01674889     EISSN: 18792596     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2016.01.005     Document Type: Article

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