Parallel pathways in RAF-induced senescence and conditions for its reversion

Oncogene

Volumn 31, Issue 25, 2012, Pages 3072-3085

  Jeanblanc, M ^a   Ragu, S ^a   Gey, C ^a,b   Contrepois, K ^a   Courbeyrette, R ^a   Thuret, J Y ^a   Mann, C ^a  

^a SERVICE DE CHIMIE BIOORGANIQUE ET DE MARQUAGE   (France)

^b UNIVERSITY OF LÜBECK   (Germany)

Author keywords

CKI; DNA damage; oxidative stress; RAF kinase; senescence

Indexed keywords

AFIMOXIFENE; CELL DNA; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE INHIBITOR 1A; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLIN DEPENDENT KINASE INHIBITOR 2A; CYCLIN DEPENDENT KINASE INHIBITOR 2B; GREEN FLUORESCENT PROTEIN; HISTONE H2AX; MITOGEN ACTIVATED PROTEIN KINASE P38; OXYGEN; PHOSPHATIDYLETHANOLAMINE BINDING PROTEIN; PROTEIN P21; REACTIVE OXYGEN METABOLITE;

ARTICLE; CELL AGING; CELL CYCLE ARREST; CELL CYCLE S PHASE; CELL DIVISION; CELL IMMORTALIZATION; CELL PROLIFERATION; CELL STIMULATION; CELL STRESS; CONTROLLED STUDY; CULTURE MEDIUM; DNA DAMAGE; ENDOPLASMIC RETICULUM; ENZYME ACTIVATION; ENZYME INACTIVATION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; FIBROBLAST CULTURE; GENE INACTIVATION; HETEROCHROMATIN; HISTONE PHOSPHORYLATION; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN SYNTHESIS; SENESCENCE;

CELL AGING; CONTACT INHIBITION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; FIBROBLASTS; HUMANS; NEOPLASM PROTEINS; OXYGEN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PROTO-ONCOGENE PROTEINS C-RAF; REACTIVE OXYGEN SPECIES; SERUM;

EID: 84862642872     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.481     Document Type: Article

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