Identification of senescence-associated genes and their networks under oxidative stress by the analysis of bach1

Antioxidants and Redox Signaling

Volumn 14, Issue 12, 2011, Pages 2441-2451

  Ota, Kazushige ^a,b   Dohi, Yoshihiro ^a,c   Brydun, Andrey ^a,b   Nakanome, Ayako ^a   Ito, Sadayoshi ^b   Igarashi, Kazuhiko ^a,b  

^a Department of Biochemistry ^*  (Japan)

^b TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^c HIROSHIMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; HEME OXYGENASE 1; P21 ACTIVATED KINASE; PROTEIN P53; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR BACH1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL AGING; CELL CYCLE; CELL PROLIFERATION; FIBROBLAST; GENE AMPLIFICATION; GENE EXPRESSION; GENE IDENTIFICATION; GENE TARGETING; IMMUNOBLOTTING; MOUSE; MOUSE EMBRYONIC FIBROBLAST; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; TRANSCRIPTION INITIATION;

ANIMALS; BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTORS; CELL AGING; CELLS, CULTURED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYCLIN-DEPENDENT KINASE INHIBITOR P21; FIBROBLASTS; GENE REGULATORY NETWORKS; HEME OXYGENASE-1; MICE; OXIDATIVE STRESS; RETINOBLASTOMA PROTEIN; RNA INTERFERENCE; TUMOR SUPPRESSOR PROTEIN P53;

EID: 79957466048     PISSN: 15230864     EISSN: 15577716     Source Type: Journal    
DOI: 10.1089/ars.2010.3574     Document Type: Article

References (40)

1. Abbas T and Dutta A. p21 in cancer: intricate networks and multiple activities. Nat Rev Cancer 9: 400-414, 2009.
2. Artavanis-Tsakonas S, Rand MD, and Lake RJ. Notch signaling: cell fate control and signal integration in development. Science 284: 770-776, 1999. (Pubitemid 29291335)
3. Attardi LD, Reczek EE, Cosmas C, Demicco EG, McCurrach ME, Lowe SW, and Jacks T. PERP, an apoptosis-associated target of p53, is a novel member of the PMP-22/gas3 family. Genes Dev 14: 704-718, 2000. (Pubitemid 30176824)
4. Banin S, Moyal L, Shieh S, Taya Y, Anderson CW, Chessa L, Smorodinsky NI, Prives C, Reiss Y, Shiloh Y, and Ziv Y. Enhanced phosphorylation of p53 by ATM in response to DNA damage. Science 281: 1674-1677, 1998.
5. Bartkova J, Rezaei N, Liontos M, Karakaidos P, Kletsas D, Issaeva N, Vassiliou LV, Kolettas E, Niforou K, Zoumpourlis VC, Takaoka M, Nakagawa H, Tort F, Fugger K, Johansson F, Sehested M, Andersen CL, Dyrskjot L, Orntoft T, Lukas J, Kittas C, Helleday T, Halazonetis TD, Bartek J, and Gorgoulis VG. Oncogene-induced senescence is part of the tumorigenesis barrier imposed by DNA damage checkpoints. Nature 444: 633-637, 2006. (Pubitemid 44864442)
6. Basak S, Jacobs SB, Krieg AJ, Pathak N, Zeng Q, Kaldis P, Giaccia AJ, and Attardi LD. The metastasis-associated gene Prl-3 is a p53 target involved in cell-cycle regulation. Mol Cell 30: 303-314, 2008. (Pubitemid 351626943)
7. Beltrao P, Cagney G, and Krogan NJ. Quantitative genetic interactions reveal biological modularity. Cell 141: 739-745, 2010.
8. Ben-Porath I and Weinberg RA. The signals and pathways activating cellular senescence. Int J Biochem Cell Biol 37: 961-976, 2005. (Pubitemid 40311739)
9. Berube C, Boucher LM, Ma WA, Wakeham A, Salmena L, Hakem R, Yeh WC, Mak TW, and Benchimol S. Apoptosis caused by p53-induced protein with death domain (PIDD) depends on the death adapter protein RAIDD. Proc Natl Acad Sci USA 102: 14314-14320, 2005.
10. Brigelius-Flohe R. Tissue-specific functions of individual glutathione peroxidases. Free Radic BiolMed 27: 951-965, 1999. (Pubitemid 29507469)
11. Brugarolas J, Bronson RT, and Jacks T. p21 is a critical CDK2 regulator essential for proliferation control in Rb-deficient cells. J Cell Biol 141: 503-514, 1998. (Pubitemid 28237097)
12. Campisi J. Cellular senescence as a tumor-suppressor mechanism. Trends Cell Biol 11: S27-S31, 2001.
13. Collado M, Gil J, Efeyan A, Guerra C, Schuhmacher AJ, Barradas M, Benguria A, Zaballos A, Flores JM, Barbacid M, Beach D, and Serrano M. Tumour biology: senescence in premalignant tumours. Nature 436: 642, 2005. (Pubitemid 41117258)
14. d'Adda di Fagagna F, Reaper PM, Clay-Farrace L, Fiegler H, Carr P, Von Zglinicki T, Saretzki G, Carter NP, and Jackson SP. A DNA damage checkpoint response in telomere-initiated senescence. Nature 426: 194-198, 2003. (Pubitemid 37442589)
15. Dimri GP, Lee X, Basile G, Acosta M, Scott G, Roskelley C, Medrano EE, Linskens M, Rubelj I, Pereira-Smith O, et al. A biomarker that identifies senescent human cells in culture and in aging skin in vivo. Proc Natl Acad Sci USA 92: 9363-9367, 1995.
16. Dirac AM and Bernards R. Reversal of senescence in mouse fibroblasts through lentiviral suppression of p53. J Biol Chem 278: 11731-11734, 2003. (Pubitemid 36800139)
17. Dohi Y, Ikura T, Hoshikawa Y, Katoh Y, Ota K, Nakanome K, Muto A, Omura S, Ohta T, Ito A, Yoshida M, Noda T, and Igarashi K. Bach1 inhibits oxidative stress-induced cellular senescence by impeding p53 function on chromatin. Nat Struct Mol Biol 15: 1246-1254, 2008.
18. Duckers HJ, Boehm B, True AI, Yet SF, San H, Park JL, Clinton Webb R, Lee ME, Nabel GL, and Nabel EG. Heme oxygenase-1 protects against vascular constriction and proliferation. Nat Med 7: 693-698, 2001. (Pubitemid 32588025)
19. Harper JW, Adami GR, Wei N, Keyomarsi K, and Elledge SJ. The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases. Cell 75: 805-816, 1993. (Pubitemid 23346377)
20. Hayflick L. The limited in vitro lifetime of human diploid cell strains. Exp Cell Res 37: 614-636, 1965.
21. Hou R, Liu L, Anees S, Hiroyasu S, and Sibinga NE. The Fat1 cadherin integrates vascular smooth muscle cell growth and migration signals. J Cell Biol 173: 417-429, 2006.
22. Igarashi K and Sun J. The heme-Bach1 pathway in the regulation of oxidative stress response and erythroid differentiation. Antioxid Redox Signal 8: 107-118, 2006. (Pubitemid 43324536)
23. Jackson AL and Loeb IA. The contribution of endogenous sources of DNA damage to the multiple mutations in cancer. Mutat Res 477: 7-21, 2001. (Pubitemid 32480184)
24. Kortlever RM, Higgins PJ, and Bernards R. Plasminogen activator inhibitor-1 is a critical downstream target of p53 in the induction of replicative senescence. Nat Cell Biol 8: 877-884, 2006.
25. Krtolica A, Parrinello Lockett S, Desprez PY, and Campisi J. Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging. Proc Natl Acad Sci USA 98: 12072-12077, 2001. (Pubitemid 32959828)
26. Oda E, Ohki R, Murasawa H, Nemoto J, Shibue T, Yamashita T, Tokino T, Taniguchi T, and Tanaka N. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. Science 288: 1053-1058, 2000. (Pubitemid 30324238)
27. Oyake T, Itoh K, Motohashi H, Hayashi N, Hoshino H, Nishizawa/ M, Yamamoto M, and Igarashi K. Bach proteins belong to a novel family of BTB-basic leucine zipper transcription factors that interact with MafK and regulate transcription through the NF-E2 site. Mol Cell Biol 16: 6083-6095, 1996. (Pubitemid 26360968)
28. Pantoja C and Serrano M. Murine fibroblasts lacking p21 undergo senescence and are resistant to transformation by oncogenic Ras. Oncogene 18: 4974-4982, 1999. (Pubitemid 29425304)
29. Parrinello S, Samper E, Krtolica A, Goldstein J, Melov S, and Campisi J. Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts. Nat Cell Biol 5: 741-747, 2003. (Pubitemid 36986782)
30. Pascal T, Debacq-Chainiaux F, Boilan E, Ninane N. Raes M, and Toussaint O. Heme oxygenase-1 and interleukin-11 are overexpressed in stress-induced premature senescence of human WI-38 fibroblasts induced by tert- butylhydroperoxide and ethanol. Biogerontology 8: 409-422, 2007. (Pubitemid 47054798)
31. Peyton KJ, Reyna SV, Chapman GB, Ensenat D, Liu XM, Wang H, Schafer AI, and Durante W. Heme oxygenase-1-derived carbon monoxide is an autocrine inhibitor of vascular smooth muscle cell growth. Blood 99: 4443-4448, 2002. (Pubitemid 34627213)
32. Pomerantz J, Schreiber-Agus N, Liegeois NJ, Silverman A, Alland L, Chin L, Potes J, Chen K, Orlow I, Lee HW, Cordon-Cardo C, DePinho RA. The Ink4a tumor suppressor gene product, p19Arf, interacts with MDM2 and neutralizes MDM2's inhibition of p53. Cell 92: 713-723, 1998. (Pubitemid 28155311)
33. Redies C, Vanhalst K, and Roy F. delta-Protocadherins: unique structures and functions. Cell Mol Life Sci 62: 2840-2852, 2005. (Pubitemid 41779950)
34. Sablina AA, Budanov AV, Ilyinskaya GV, Agapova LS, Kravchenko JE, and Chumakov PM. The antioxidant function of the p53 tumor suppressor. Nat Med 11: 1306-1313, 2005. (Pubitemid 41752911)
35. Sage J, Miller AL, Perez-Mancera PA, Wysocki JM, and Jacks T. Acute mutation of retinoblastoma gene function is suffi-cient for cell cycle re-entry. Nature 424: 223-228, 2003. (Pubitemid 36858693)
36. Sage J, Mulligan GF, Attardi LD, Miller A, Chen S, Williams B, Theodorou E, and Jacks T. Targeted disruption of the three Rb-related genes leads to loss of G(1) control and immortalization. Genes Dev 14: 3037-3050, 2000.
37. Sionov RV and Haupt Y. The cellular response to p53: the decision between life and death. Oncogene 18: 6145-6157, 1999.
38. Siva K, Venu P, Mahadevan A, and Inamdar, MS. Human BCAS3 expression in embryonic stem cells and vascular precursors suggests a role in human embryogenesis and tumor angiogenesis. PLoS ONE 2: e1202, 2007.
39. Sun J, Hoshino H, Takaku K, Nakajima O, Muto A, Suzuki H, Tashiro S, Takahashi S, Shibahara S, Alam J, Taketo MM, Yamamoto M, and Igarashi K. Hemoprotein Bach1 regulates enhancer availability of heme oxygenase-1 gene. EMBO J 21: 5216-5224, 2002.
40. Weinberg RA. The retinoblastoma protein and cell cycle control. Cell 81: 323-330, 1995.