-
2
-
-
77956410642
-
New applications and mechanisms of action of saffron and its important ingredients
-
Bathaie SZ, Mousavi SZ,. New applications and mechanisms of action of saffron and its important ingredients. Crit Rev Food Scu Nutr 2010; 50: 761-786.
-
(2010)
Crit Rev Food Scu Nutr
, vol.50
, pp. 761-786
-
-
Bathaie, S.Z.1
Mousavi, S.Z.2
-
3
-
-
34548445132
-
Saffron in phytotherapy: Pharmacology and clinical uses
-
Schmidt M, et al. Saffron in phytotherapy: pharmacology and clinical uses. Wien Med Wochenschr 2007; 157: 315-319.
-
(2007)
Wien Med Wochenschr
, vol.157
, pp. 315-319
-
-
Schmidt, M.1
-
6
-
-
79958215240
-
Cardiovascular effects of saffron: An evidence-based review
-
Kamalipour M, et al. Cardiovascular effects of saffron: an evidence-based review. Teh Univ Heart Ctr 2011; 6: 59-61.
-
(2011)
Teh Univ Heart Ctr
, vol.6
, pp. 59-61
-
-
Kamalipour, M.1
-
7
-
-
0642339654
-
Studies on the pharmacological effects of saffron (Crocus sativus L.) - A review
-
Deng Y, et al. Studies on the pharmacological effects of saffron (Crocus sativus L.)-A review. Zhonguo Zhongn Yao Za Zhi 2002; 27: 565-568.
-
(2002)
Zhonguo Zhongn Yao Za Zhi
, vol.27
, pp. 565-568
-
-
Deng, Y.1
-
8
-
-
2942615338
-
Crocetin from saffron: An active component of an ancient spice
-
Giaccio M,. Crocetin from saffron: an active component of an ancient spice. Crit Rev Food Sci Nutr 2004; 44: 155-172.
-
(2004)
Crit Rev Food Sci Nutr
, vol.44
, pp. 155-172
-
-
Giaccio, M.1
-
9
-
-
49349104502
-
Pharmacological activities of crocin in saffron
-
Soeda S, et al. Pharmacological activities of crocin in saffron. J Nat Med 2007; 61: 102-111.
-
(2007)
J Nat Med
, vol.61
, pp. 102-111
-
-
Soeda, S.1
-
10
-
-
84897922015
-
Pharmacological profile of Crocus sativus - A comprehensive review
-
Kumar V, et al. Pharmacological profile of Crocus sativus-A comprehensive review. Pharmacologyonline 2011; 3: 789-811.
-
(2011)
Pharmacologyonline
, vol.3
, pp. 789-811
-
-
Kumar, V.1
-
11
-
-
84969317502
-
Clinical applications of saffron (Crocus sativus) and its constituents: A review
-
Moshiri M, et al. Clinical applications of saffron (Crocus sativus) and its constituents: a review. Drug Res 2014; 64: 1-9.
-
(2014)
Drug Res
, vol.64
, pp. 1-9
-
-
Moshiri, M.1
-
12
-
-
84890059100
-
Saffron and natural carotenoids: Biochemical activities and anti-tumor effects
-
Bolhassani A, et al. Saffron and natural carotenoids: biochemical activities and anti-tumor effects. Biochim Biophys Acta 2014; 1845: 20-30.
-
(2014)
Biochim Biophys Acta
, vol.1845
, pp. 20-30
-
-
Bolhassani, A.1
-
13
-
-
84940164645
-
Crocus sativus L. (saffron) for cancer chemoprevention: A mini review
-
Bhandari P,. Crocus sativus L. (saffron) for cancer chemoprevention: a mini review. J Trad ComplementMed 2015; 5: 81-87.
-
(2015)
J Trad ComplementMed
, vol.5
, pp. 81-87
-
-
Bhandari, P.1
-
14
-
-
84923875933
-
The effect of Crocus sativus L. and its constituents on memory: Basic studies and clinical applications
-
Pitsikas N,. The effect of Crocus sativus L. and its constituents on memory: basic studies and clinical applications. Evid Based Complement Alternat Med 2015; 2015: 1-7. http://dx.doi.org/10.1155/2015/926284.
-
(2015)
Evid Based Complement Alternat Med
, vol.2015
, pp. 1-7
-
-
Pitsikas, N.1
-
15
-
-
0343819945
-
Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): An experimental study in the rats
-
Garcia-Olmo DC, et al. Effects of long-term treatment of colon adenocarcinoma with crocin, a carotenoid from saffron (Crocus sativus L.): an experimental study in the rats. Nutr Cancer 1999; 35: 120-126.
-
(1999)
Nutr Cancer
, vol.35
, pp. 120-126
-
-
Garcia-Olmo, D.C.1
-
16
-
-
58149391823
-
Cytotoxic effect of saffron stigma aqueous extract on human transitional cell carcinoma and mouse fibroblast
-
Feizzadeh B, et al. Cytotoxic effect of saffron stigma aqueous extract on human transitional cell carcinoma and mouse fibroblast. Urol J 2008; 5: 161-167.
-
(2008)
Urol J
, vol.5
, pp. 161-167
-
-
Feizzadeh, B.1
-
17
-
-
75249099832
-
Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats
-
Goyal S, et al. Preventive effect of crocin of Crocus sativus on hemodynamic, biochemical, histopathological and ultrastuctural alterations in isoproterenol-induced cardiotoxicity in rats. Phytomedicine 2010; 17: 227-232.
-
(2010)
Phytomedicine
, vol.17
, pp. 227-232
-
-
Goyal, S.1
-
18
-
-
77951140139
-
The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction
-
Joukar S, et al. The effect of saffron consumption on biochemical and histopathological heart indices of rats with myocardial infarction. Cardiovasc Toxicol 2010; 10: 66-71.
-
(2010)
Cardiovasc Toxicol
, vol.10
, pp. 66-71
-
-
Joukar, S.1
-
19
-
-
84866909578
-
Effects of the active constituents of Crocus sativus L., crocins, in an animal modelof obsessive-compulsive disorder
-
Georgiadou G, et al. Effects of the active constituents of Crocus sativus L., crocins, in an animal modelof obsessive-compulsive disorder. Neurosci Lett 2012; 528: 27-30.
-
(2012)
Neurosci Lett
, vol.528
, pp. 27-30
-
-
Georgiadou, G.1
-
20
-
-
84888260574
-
Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer
-
Bathaie SZ, et al. Anticancer effects of crocetin in both human adenocarcinoma gastric cancer cells and rat model of gastric cancer. Biochem Cell Biol 2013; 91: 397-403.
-
(2013)
Biochem Cell Biol
, vol.91
, pp. 397-403
-
-
Bathaie, S.Z.1
-
21
-
-
84876552067
-
Crocin inhibits antitumor effects on human leukemia HL-60 cells in vitro and in vivo
-
Sun Y, et al. Crocin inhibits antitumor effects on human leukemia HL-60 cells in vitro and in vivo. Evid Based Complement Alternat Med 2013; 2013: 1-7.
-
(2013)
Evid Based Complement Alternat Med
, vol.2013
, pp. 1-7
-
-
Sun, Y.1
-
22
-
-
39449112686
-
Effect of safranal, a constituent of saffron (Crocus sativus L.) on lipid peroxidation level during renal ischemia-reperfusion injury in rats
-
Sadeghnia HR, et al. Effect of safranal, a constituent of saffron (Crocus sativus L.) on lipid peroxidation level during renal ischemia-reperfusion injury in rats. Iran J Basic Med Sci Fall 2005; 8: 179-185.
-
(2005)
Iran J Basic Med Sci Fall
, vol.8
, pp. 179-185
-
-
Sadeghnia, H.R.1
-
26
-
-
9644268896
-
Biomedical properties of saffron and its potential uses in cancer therapy and chemoprevention trials
-
Abdullaev FI, Espinosa-Aquirre JJ,. Biomedical properties of saffron and its potential uses in cancer therapy and chemoprevention trials. Cancer Detect Prev 2004; 28: 426-432.
-
(2004)
Cancer Detect Prev
, vol.28
, pp. 426-432
-
-
Abdullaev, F.I.1
Espinosa-Aquirre, J.J.2
-
27
-
-
33644778804
-
Protective effect of saffron (Crocus sativus L.) aqueous extract against genetic damage induced by anti-tumor agents in mice
-
Premkumar K, et al. Protective effect of saffron (Crocus sativus L.) aqueous extract against genetic damage induced by anti-tumor agents in mice. Hum Exp Toxicol 2006; 25: 79-84.
-
(2006)
Hum Exp Toxicol
, vol.25
, pp. 79-84
-
-
Premkumar, K.1
-
28
-
-
82155184517
-
Immunomodulatory effects of saffron: A randomized double-blind placebo-controlled clinical trial
-
Kianbakht S, Ghazavi A,. Immunomodulatory effects of saffron: a randomized double-blind placebo-controlled clinical trial. Phytother Res 2011; 25: 1801-1805.
-
(2011)
Phytother Res
, vol.25
, pp. 1801-1805
-
-
Kianbakht, S.1
Ghazavi, A.2
-
29
-
-
79961206003
-
Determination of antioxidant activity of saffron taken from the flower of Crocus sativus grown in Lebanon
-
Makhlouf H, et al. Determination of antioxidant activity of saffron taken from the flower of Crocus sativus grown in Lebanon. Afr J Biotechnol 2011; 10: 8093-8100.
-
(2011)
Afr J Biotechnol
, vol.10
, pp. 8093-8100
-
-
Makhlouf, H.1
-
30
-
-
18444399219
-
Crocus sativus L. in the treatment of mild to moderate depression: A double blind, randomized and placebo controlled trial
-
Akhondzadeh S, et al. Crocus sativus L. in the treatment of mild to moderate depression: a double blind, randomized and placebo controlled trial. Phytother Res 2005; 19: 148-151.
-
(2005)
Phytother Res
, vol.19
, pp. 148-151
-
-
Akhondzadeh, S.1
-
31
-
-
13544274008
-
Hydroalcoholic extract of Crocus sativus L versus fluoxetine in the treatment of mild to moderate depression: A double-blind, randomized pilot trial
-
Noorbala A, et al. Hydroalcoholic extract of Crocus sativus L versus fluoxetine in the treatment of mild to moderate depression: a double-blind, randomized pilot trial. J Ethnopharmacol 2005; 97: 281-284.
-
(2005)
J Ethnopharmacol
, vol.97
, pp. 281-284
-
-
Noorbala, A.1
-
32
-
-
38949193873
-
Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: A double-blind, randomised and placebo controlled trial
-
Agha-Hosseini M, et al. Crocus sativus L. (saffron) in the treatment of premenstrual syndrome: a double-blind, randomised and placebo controlled trial. BJOG 2008; 115: 515-519.
-
(2008)
BJOG
, vol.115
, pp. 515-519
-
-
Agha-Hosseini, M.1
-
33
-
-
72049130825
-
A 22-week multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease
-
Akhondzadeh S, et al. A 22-week multicenter, randomized, double-blind controlled trial of Crocus sativus in the treatment of mild-to-moderate Alzheimer's disease. Psychopharmacology (Berl) 2010; 207: 637-643.
-
(2010)
Psychopharmacology (Berl)
, vol.207
, pp. 637-643
-
-
Akhondzadeh, S.1
-
34
-
-
0011030944
-
Riboflavine and thiamine contents of saffron, Crocus sativus
-
Bhat JV, Broker R,. Riboflavine and thiamine contents of saffron, Crocus sativus. Nature 1953; 172: 544-545.
-
(1953)
Nature
, vol.172
, pp. 544-545
-
-
Bhat, J.V.1
Broker, R.2
-
35
-
-
77957043191
-
Constituents of Crocus sativus L. Bulbs
-
Loukis A, et al. Constituents of Crocus sativus L. bulbs. Plant Med Phytother 1983; 17: 89-91.
-
(1983)
Plant Med Phytother
, vol.17
, pp. 89-91
-
-
Loukis, A.1
-
36
-
-
0029934789
-
An update review of saffron and its active constituents
-
Rios JL, et al. An update review of saffron and its active constituents. Phytother Res 1996; 10: 189-193.
-
(1996)
Phytother Res
, vol.10
, pp. 189-193
-
-
Rios, J.L.1
-
37
-
-
0034367581
-
Saffron-renewed interest in an ancient spice
-
Winterhalter P, Straubinger M,. Saffron-renewed interest in an ancient spice. Food Rev Int 2000; 16: 39-59.
-
(2000)
Food Rev Int
, vol.16
, pp. 39-59
-
-
Winterhalter, P.1
Straubinger, M.2
-
38
-
-
33745216323
-
Biology, biotechnology and biomedicine of saffron
-
Fernandez JA,. Biology, biotechnology and biomedicine of saffron. Recent Res Devel Plant Sc 2004; 2: 127-159.
-
(2004)
Recent Res Devel Plant Sc
, vol.2
, pp. 127-159
-
-
Fernandez, J.A.1
-
39
-
-
0035535412
-
Composition of crocins and picrocrocin from Spanish saffron (Crocus sativus L)
-
Alonso GL, et al. Composition of crocins and picrocrocin from Spanish saffron (Crocus sativus L). J Food Qual 2001; 24: 219-233.
-
(2001)
J Food Qual
, vol.24
, pp. 219-233
-
-
Alonso, G.L.1
-
40
-
-
0000359529
-
Absolute configuration of picrocrocin
-
Buchecker R, Eugster CH,. Absolute configuration of picrocrocin. Helv Chi Acta 1973; 56: 1121-1124.
-
(1973)
Helv Chi Acta
, vol.56
, pp. 1121-1124
-
-
Buchecker, R.1
Eugster, C.H.2
-
41
-
-
0007141752
-
Valutazione della frazione volatile dello zafferano mediante gascromatografia dello spazio di testa
-
Curro P, et al. Valutazione della frazione volatile dello zafferano mediante gascromatografia dello spazio di testa. Rassegna Chimica 1986; 38: 331-334.
-
(1986)
Rassegna Chimica
, vol.38
, pp. 331-334
-
-
Curro, P.1
-
42
-
-
0041635067
-
Picrocrocin, the terpene glucoside of saffron and the biogenesis of the carotenoid-carboxylic acid
-
Kuhn R, Winterstein G,. Picrocrocin, the terpene glucoside of saffron and the biogenesis of the carotenoid-carboxylic acid. Naturwissenschaften 1933; 21: 527.
-
(1933)
Naturwissenschaften
, vol.21
, pp. 527
-
-
Kuhn, R.1
Winterstein, G.2
-
43
-
-
0005007093
-
Minor carotenoid glycosides from saffron (Crocus sativus)
-
Dhingra VK, et al. Minor carotenoid glycosides from saffron (Crocus sativus). Indian J Chem 1975; 13: 339-341.
-
(1975)
Indian J Chem
, vol.13
, pp. 339-341
-
-
Dhingra, V.K.1
-
44
-
-
0002356461
-
13-cis-crocin: A new crocinoid of saffron
-
Speranza G, et al. 13-cis-crocin: a new crocinoid of saffron. Gazz Chim It 1984; 114: 189-192.
-
(1984)
Gazz Chim It
, vol.114
, pp. 189-192
-
-
Speranza, G.1
-
47
-
-
2942614520
-
Purpura resulting from artificial abortion
-
Frank A,. Purpura resulting from artificial abortion. Deut Med Wochschr 1961; 86: 1618-1620.
-
(1961)
Deut Med Wochschr
, vol.86
, pp. 1618-1620
-
-
Frank, A.1
-
48
-
-
10444231865
-
Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: A pilot double-blind randomized trial
-
Akhondzadeh S, et al. Comparison of Crocus sativus L. and imipramine in the treatment of mild to moderate depression: a pilot double-blind randomized trial. BMC Complement Altern Med 2004; 4: 12.
-
(2004)
BMC Complement Altern Med
, vol.4
, pp. 12
-
-
Akhondzadeh, S.1
-
49
-
-
33846820128
-
Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: A pilot doubleblind randomized trial
-
Akhondzadeh Basti A, et al. Comparison of petal of Crocus sativus L. and fluoxetine in the treatment of depressed outpatients: a pilot doubleblind randomized trial. Prog Neuropsychopharmacol Biol Psychiatry 2007; 31: 439-442.
-
(2007)
Prog Neuropsychopharmacol Biol Psychiatry
, vol.31
, pp. 439-442
-
-
Akhondzadeh Basti, A.1
-
50
-
-
77952016251
-
Effect of Crocus sativus L. (saffron) stigma and its constituents, crocin and safranal, on morphine withdrawal syndrome in mice
-
Hosseinzadeh H, Jahanian Z,. Effect of Crocus sativus L. (saffron) stigma and its constituents, crocin and safranal, on morphine withdrawal syndrome in mice. Phytother Res 2010; 24: 726-730.
-
(2010)
Phytother Res
, vol.24
, pp. 726-730
-
-
Hosseinzadeh, H.1
Jahanian, Z.2
-
51
-
-
79955621804
-
Effects of crocin on the acquisition and reinstatement of morphine-induced conditioned place preference in mice
-
Imenshahidi M, et al. Effects of crocin on the acquisition and reinstatement of morphine-induced conditioned place preference in mice. Pharmacologyonline 2011; 1: 1007-1013.
-
(2011)
Pharmacologyonline
, vol.1
, pp. 1007-1013
-
-
Imenshahidi, M.1
-
52
-
-
84858005351
-
Effects of saffron (Crocus sativus L.) and its active constituent, crocin, on recognition and spatial memory, after chronic cerebral hypoperfusion in rats
-
Hosseinzadeh H, et al. Effects of saffron (Crocus sativus L.) and its active constituent, crocin, on recognition and spatial memory, after chronic cerebral hypoperfusion in rats. Phytother Res 2012; 26: 381-386.
-
(2012)
Phytother Res
, vol.26
, pp. 381-386
-
-
Hosseinzadeh, H.1
-
53
-
-
67149128716
-
Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice
-
Hosseinzadeh H, Noraei NB,. Anxiolytic and hypnotic effect of Crocus sativus aqueous extract and its constituents, crocin and safranal, in mice. Phytother Res 2009; 23: 768-774.
-
(2009)
Phytother Res
, vol.23
, pp. 768-774
-
-
Hosseinzadeh, H.1
Noraei, N.B.2
-
54
-
-
77956625933
-
Saffron in the treatment of patients with mild to moderate Alzheimer's disease: A 16-week, a randomized and placebo controlled trial
-
Akhondzadeh S, et al. Saffron in the treatment of patients with mild to moderate Alzheimer's disease: a 16-week, a randomized and placebo controlled trial. J Clin Pharm and Ther 2010; 35: 581-585.
-
(2010)
J Clin Pharm and Ther
, vol.35
, pp. 581-585
-
-
Akhondzadeh, S.1
-
55
-
-
23944510393
-
Neuroprotection by crocetin in a hemi-Parkinsonian rat model
-
Ahmad AS, et al. Neuroprotection by crocetin in a hemi-Parkinsonian rat model. Pharmacol Biochem Behav 2005; 81: 805-813.
-
(2005)
Pharmacol Biochem Behav
, vol.81
, pp. 805-813
-
-
Ahmad, A.S.1
-
56
-
-
81255167465
-
Anti-hyperglycemic effetcs of saffron and its active constituents, crocin and safranalm in alloxan-induced diabetic rats
-
Kianbakht S, Hajiaghaee R,. Anti-hyperglycemic effetcs of saffron and its active constituents, crocin and safranalm in alloxan-induced diabetic rats. J Med Plants 2011; 10: 82-89.
-
(2011)
J Med Plants
, vol.10
, pp. 82-89
-
-
Kianbakht, S.1
Hajiaghaee, R.2
-
57
-
-
84879931492
-
Effect of crocin on the insulin resistance and lipid profile of streptozotocin-induced diabetic rats
-
Shirali S, et al. Effect of crocin on the insulin resistance and lipid profile of streptozotocin-induced diabetic rats. Phytother Res 2013; 27: 1042-1047.
-
(2013)
Phytother Res
, vol.27
, pp. 1042-1047
-
-
Shirali, S.1
-
58
-
-
84865335235
-
Saffron (Crocus sativus L.) increases glucose uptake and insulin sensitivity in muscle cells via multipathway mechanisms
-
Kang C, et al. Saffron (Crocus sativus L.) increases glucose uptake and insulin sensitivity in muscle cells via multipathway mechanisms. Food Chem 2012; 135: 2350-2358.
-
(2012)
Food Chem
, vol.135
, pp. 2350-2358
-
-
Kang, C.1
-
59
-
-
20444445184
-
Effect of crocin on experimental atherosclerosis in quails and its mechanisms
-
He S, et al. Effect of crocin on experimental atherosclerosis in quails and its mechanisms. Life Sci 2005; 77: 907-921.
-
(2005)
Life Sci
, vol.77
, pp. 907-921
-
-
He, S.1
-
60
-
-
84865250865
-
Akt/GSK-3b/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia-reperfusion injury in rats
-
Bharti S, et al. Akt/GSK-3b/eNOS phosphorylation arbitrates safranal-induced myocardial protection against ischemia-reperfusion injury in rats. Eur J Nutr 2011; 51: 719-727.
-
(2011)
Eur J Nutr
, vol.51
, pp. 719-727
-
-
Bharti, S.1
-
61
-
-
85052639147
-
The impact of saffron administration on atherosclerosis development in an experimental animal model
-
November 2-6, 2014, San Diego, USA
-
Christodoulou E, et al. (2014) The impact of saffron administration on atherosclerosis development in an experimental animal model. AAPS Annual Meeting and Exposition, November 2-6, 2014, San Diego, USA.
-
(2014)
AAPS Annual Meeting and Exposition
-
-
Christodoulou, E.1
-
62
-
-
0025809643
-
Antitumour activity of saffron (Crocus sativus)
-
Nair SC, et al. Antitumour activity of saffron (Crocus sativus). Cancer Lett 1991; 57: 109-114.
-
(1991)
Cancer Lett
, vol.57
, pp. 109-114
-
-
Nair, S.C.1
-
63
-
-
84872845613
-
Saffron aqueous extract inhibits the chemically-induced gastric cancer progression in the Wistar albino rat
-
Bathaie SZ, et al. Saffron aqueous extract inhibits the chemically-induced gastric cancer progression in the Wistar albino rat. Iran J Basic Med Sci 2013b; 16: 27-38.
-
(2013)
Iran J Basic Med Sci
, vol.16
, pp. 27-38
-
-
Bathaie, S.Z.1
-
64
-
-
58849111842
-
The effect of Saffron (Crocus sativus) extract for healing of second-degree burn wound in rats
-
Khorasani G, et al. The effect of Saffron (Crocus sativus) extract for healing of second-degree burn wound in rats. Keio J Med 2008; 57: 190-195.
-
(2008)
Keio J Med
, vol.57
, pp. 190-195
-
-
Khorasani, G.1
-
65
-
-
44649100242
-
The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats
-
Hosseinzadeh H, et al. The effect of saffron, Crocus sativus stigma, extract and its constituents, safranal and crocin on sexual behaviors in normal male rats. Phytomedicine 2008; 15: 491-495.
-
(2008)
Phytomedicine
, vol.15
, pp. 491-495
-
-
Hosseinzadeh, H.1
-
66
-
-
39449108601
-
Protective effect of safranal against hexachlorobutadiene-induced nephrotoxicity in rat
-
Boroushaki MT, et al. Protective effect of safranal against hexachlorobutadiene-induced nephrotoxicity in rat. Iran J Med Sci 2007; 32: 173-176.
-
(2007)
Iran J Med Sci
, vol.32
, pp. 173-176
-
-
Boroushaki, M.T.1
-
67
-
-
82155197279
-
Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice
-
Halataei BS, et al. Saffron (Crocus sativus) aqueous extract and its constituent crocin reduces stress-induced anorexia in mice. Phytother Res 2011; 25: 1833-1838.
-
(2011)
Phytother Res
, vol.25
, pp. 1833-1838
-
-
Halataei, B.S.1
-
68
-
-
10444251371
-
Study of antidepressant effect of aqueous and ethanolic extracts of Crocus sativus in mice
-
Karimi G, et al. Study of antidepressant effect of aqueous and ethanolic extracts of Crocus sativus in mice. Iranian Basic Med Sci 2001; 4: 11-15.
-
(2001)
Iranian Basic Med Sci
, vol.4
, pp. 11-15
-
-
Karimi, G.1
-
69
-
-
27444432701
-
Antidepressant effect of Crocus sativus L. Stigma extracts and their constituents, crocin and safranal, in mice
-
Hosseinzadeh H, et al. Antidepressant effect of Crocus sativus L. stigma extracts and their constituents, crocin and safranal, in mice. Acta Hort 2004; 650: 435-445.
-
(2004)
Acta Hort
, vol.650
, pp. 435-445
-
-
Hosseinzadeh, H.1
-
70
-
-
77949490080
-
Antidepressant properties of bioactive fractions from the extract of Crocus sativus L
-
Wang H, et al. Antidepressant properties of bioactive fractions from the extract of Crocus sativus L. J Nat Med 2010; 64: 24-30.
-
(2010)
J Nat Med
, vol.64
, pp. 24-30
-
-
Wang, H.1
-
71
-
-
56249137212
-
Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety
-
Pitsikas N, et al. Effects of the active constituents of Crocus sativus L., crocins, in an animal model of anxiety. Phytomedicine 2008; 15: 1135-1139.
-
(2008)
Phytomedicine
, vol.15
, pp. 1135-1139
-
-
Pitsikas, N.1
-
72
-
-
0028090631
-
Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in-vivo
-
Sugiura M, et al. Crocin (crocetin di-gentiobiose ester) prevents the inhibitory effect of ethanol on long-term potentiation in the dentate gyrus in-vivo. J Pharmacol Exper Ther 1994; 271: 703-707.
-
(1994)
J Pharmacol Exper Ther
, vol.271
, pp. 703-707
-
-
Sugiura, M.1
-
73
-
-
0028909342
-
Ethanol extract of Crocus sativus L. Antagonizes the inhibitory action of ethanol on hippocampal long-term potentiation in vivo
-
Sugiura M, et al. Ethanol extract of Crocus sativus L. antagonizes the inhibitory action of ethanol on hippocampal long-term potentiation in vivo. Phytother Res 1995; 9: 100-104.
-
(1995)
Phytother Res
, vol.9
, pp. 100-104
-
-
Sugiura, M.1
-
74
-
-
0033399114
-
Saffron extract prevents acetaldehyde-induced inhibition of long-term potentiation in the rat dentate gyrus in vivo
-
Abe K, et al. Saffron extract prevents acetaldehyde-induced inhibition of long-term potentiation in the rat dentate gyrus in vivo. Brain Res 1999; 851: 287-289.
-
(1999)
Brain Res
, vol.851
, pp. 287-289
-
-
Abe, K.1
-
75
-
-
0034087334
-
Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation
-
Abe K, Saito H,. Effects of saffron extract and its constituent crocin on learning behaviour and long-term potentiation. Phytother Res 2000; 14: 149-152.
-
(2000)
Phytother Res
, vol.14
, pp. 149-152
-
-
Abe, K.1
Saito, H.2
-
76
-
-
10044219993
-
-
2nd edn. Boca Raton, FL, USA: CRC Press/Taylor and Francis Group
-
Ebadi M,. Pharmacodynamic Basis of Herbal Medicine, 2nd edn. Boca Raton, FL, USA: CRC Press/Taylor and Francis Group, 2007: 525-527.
-
(2007)
Pharmacodynamic Basis of Herbal Medicine
, pp. 525-527
-
-
Ebadi, M.1
-
77
-
-
33751305217
-
Inhibitory activity on amyloid-β- aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents
-
Papandreou MA, et al. Inhibitory activity on amyloid-β- aggregation and antioxidant properties of Crocus sativus stigmas extract and its crocin constituents. J Agric Food Chem 2006; 54: 8762-8768.
-
(2006)
J Agric Food Chem
, vol.54
, pp. 8762-8768
-
-
Papandreou, M.A.1
-
79
-
-
84875160569
-
Antihyperglycemic and antioxidant activity of crocin in streptozocin-induced diabetic rats
-
Rajaei Z, et al. Antihyperglycemic and antioxidant activity of crocin in streptozocin-induced diabetic rats. J Med Food 2013; 16: 1-5.
-
(2013)
J Med Food
, vol.16
, pp. 1-5
-
-
Rajaei, Z.1
-
80
-
-
29244478599
-
Radical scavenging activity of Crocus sativus L. Extract and its bioactive constituents
-
Assimopoulou AN, et al. Radical scavenging activity of Crocus sativus L. extract and its bioactive constituents. Phytother Res 2005; 19: 997-1000.
-
(2005)
Phytother Res
, vol.19
, pp. 997-1000
-
-
Assimopoulou, A.N.1
-
81
-
-
67349161842
-
An overview of structural features of DNA and RNA complexes with saffron compounds: Models and antioxidant activity
-
Kanakis CD, et al. An overview of structural features of DNA and RNA complexes with saffron compounds: models and antioxidant activity. J Phytochem Photobiol B 2009; 95: 204-212.
-
(2009)
J Phytochem Photobiol B
, vol.95
, pp. 204-212
-
-
Kanakis, C.D.1
-
82
-
-
33846856493
-
DNA interaction with saffron's secondary metabolites safranal, crocetin, and dimethylcrocetin
-
Kanakis CD, et al. DNA interaction with saffron's secondary metabolites safranal, crocetin, and dimethylcrocetin. DNA Cell Biol 2007a; 26: 63-70.
-
(2007)
DNA Cell Biol
, vol.26
, pp. 63-70
-
-
Kanakis, C.D.1
-
83
-
-
34250714871
-
Interaction of tRNA with safranal, crocetin and dimethylcrocetin
-
Kanakis CD, et al. Interaction of tRNA with safranal, crocetin and dimethylcrocetin. J Biomol Struct Dyn 2007b; 24: 537-546.
-
(2007)
J Biomol Struct Dyn
, vol.24
, pp. 537-546
-
-
Kanakis, C.D.1
-
84
-
-
0005377589
-
Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen
-
Pham TQ, et al. Antioxidant properties of crocin from Gardenia jasminoides Ellis and study of the reactions of crocin with linoleic acid and crocin with oxygen. J Agric Food Chem 2000; 48: 1455-1461.
-
(2000)
J Agric Food Chem
, vol.48
, pp. 1455-1461
-
-
Pham, T.Q.1
-
85
-
-
0027184894
-
Biological effects of saffron
-
Abduallev FI,. Biological effects of saffron. Biofactors 1993; 4: 83-86.
-
(1993)
Biofactors
, vol.4
, pp. 83-86
-
-
Abduallev, F.I.1
-
86
-
-
77952093874
-
Protective effect of saffron extract and crocin on reactive oxygen species-mediated high glucose-induced toxicity in PC12 cels
-
Mousavi S, et al. Protective effect of saffron extract and crocin on reactive oxygen species-mediated high glucose-induced toxicity in PC12 cels. Cell Mol Neurobiol 2010; 30: 185-191.
-
(2010)
Cell Mol Neurobiol
, vol.30
, pp. 185-191
-
-
Mousavi, S.1
-
87
-
-
65349160963
-
Further examination of antiradical properties of Crocus sativus stigmas extract rich in crocins
-
Ordoudi SA, et al. Further examination of antiradical properties of Crocus sativus stigmas extract rich in crocins. J Agric Food Chem 2009; 57: 3080-3086.
-
(2009)
J Agric Food Chem
, vol.57
, pp. 3080-3086
-
-
Ordoudi, S.A.1
-
88
-
-
33745843700
-
Crocetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs
-
Min X, et al. Crocetin inhibits leukocyte adherence to vascular endothelial cells induced by AGEs. J Ethnopharmacol 2006; 107: 25-31.
-
(2006)
J Ethnopharmacol
, vol.107
, pp. 25-31
-
-
Min, X.1
-
89
-
-
33845985320
-
Increased expression ratio of Bcl-2/bax is associated with crocin-mediated apoptosis in bovine aortic endothelial cells
-
Xu G, et al. Increased expression ratio of Bcl-2/bax is associated with crocin-mediated apoptosis in bovine aortic endothelial cells. Basic Clin Pharmacol Toxicol 2007; 100: 31-35.
-
(2007)
Basic Clin Pharmacol Toxicol
, vol.100
, pp. 31-35
-
-
Xu, G.1
-
90
-
-
84890412330
-
Bioactivity assessment and toxicity of crocin: A comprehensive review
-
Alavizadeh SH, Hosseinzadeh H,. Bioactivity assessment and toxicity of crocin: a comprehensive review. Food Chem Toxicol 2014; 64: 65-80.
-
(2014)
Food Chem Toxicol
, vol.64
, pp. 65-80
-
-
Alavizadeh, S.H.1
Hosseinzadeh, H.2
-
92
-
-
0027284386
-
The effect of crocetin on hemorrhagic shock in rats
-
Gainer JL, et al. The effect of crocetin on hemorrhagic shock in rats. Circ Shock 1993; 41: 1-7.
-
(1993)
Circ Shock
, vol.41
, pp. 1-7
-
-
Gainer, J.L.1
-
93
-
-
2942701971
-
Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: Possible involvement of protein kinase C
-
Fatehi Hassanabad Z, et al. Endothelial dysfunction in aortic rings and mesenteric beds isolated from deoxycorticosterone acetate hypertensive rats: possible involvement of protein kinase C. Eur J Pharmacol 2004; 494: 199-204.
-
(2004)
Eur J Pharmacol
, vol.494
, pp. 199-204
-
-
Fatehi Hassanabad, Z.1
-
94
-
-
27444442382
-
Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus
-
Hosseinzadeh H, Sadeghnia HR,. Safranal, a constituent of Crocus sativus (saffron), attenuated cerebral ischemia induced oxidative damage in rat hippocampus. J Pharm Pharm Sci 2005; 8: 394-399.
-
(2005)
J Pharm Pharm Sci
, vol.8
, pp. 394-399
-
-
Hosseinzadeh, H.1
Sadeghnia, H.R.2
-
95
-
-
84872832475
-
Safranal: From an aromatic natural product to a rewarding pharmacological agent
-
Rezaee R, Hosseinzadeh H,. Safranal: From an aromatic natural product to a rewarding pharmacological agent. Iran J Basic Med Sci 2013; 16: 12-26.
-
(2013)
Iran J Basic Med Sci
, vol.16
, pp. 12-26
-
-
Rezaee, R.1
Hosseinzadeh, H.2
-
96
-
-
0034633102
-
Pattern of childhood cancer mortality in Mexico
-
Abdullaev FI, et al. Pattern of childhood cancer mortality in Mexico. Arch Med Res 2000; 31: 526-531.
-
(2000)
Arch Med Res
, vol.31
, pp. 526-531
-
-
Abdullaev, F.I.1
-
97
-
-
0034105343
-
The cytotoxic effect of glucoconjugate extracted from corns of saffron plant (Crocus sativus) on human cell lines in culture
-
Escribano J, et al. The cytotoxic effect of glucoconjugate extracted from corns of saffron plant (Crocus sativus) on human cell lines in culture. Planta Med 2000; 66: 157-162.
-
(2000)
Planta Med
, vol.66
, pp. 157-162
-
-
Escribano, J.1
-
98
-
-
84907828121
-
Safranal, a Crocus sativus constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. in silico and in vitro study
-
Geromichalos GD, et al. Safranal, a Crocus sativus constituent suppresses the growth of K-562 cells of chronic myelogenous leukemia. In silico and in vitro study. Food Chem Toxicol 2014; 74: 45-50.
-
(2014)
Food Chem Toxicol
, vol.74
, pp. 45-50
-
-
Geromichalos, G.D.1
-
99
-
-
0036377909
-
Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L
-
Abdullaev FI,. Cancer chemopreventive and tumoricidal properties of saffron (Crocus sativus L. Exp Biol Med (Maywood) 2002; 227: 20-25.
-
(2002)
Exp Biol Med (Maywood)
, vol.227
, pp. 20-25
-
-
Abdullaev, F.I.1
-
100
-
-
77953536106
-
Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: A histopathological study
-
Das I, et al. Saffron suppresses oxidative stress in DMBA-induced skin carcinoma: a histopathological study. Acta Histochem 2010; 112: 317-327.
-
(2010)
Acta Histochem
, vol.112
, pp. 317-327
-
-
Das, I.1
-
101
-
-
16344389225
-
Pharmacological properties of N-095, a drug containing red ginseng, polygala root, saffron, antelope horn and aloe wood
-
Inoue E, et al. Pharmacological properties of N-095, a drug containing red ginseng, polygala root, saffron, antelope horn and aloe wood. Am J Chin Med 2005; 33: 49-60.
-
(2005)
Am J Chin Med
, vol.33
, pp. 49-60
-
-
Inoue, E.1
-
102
-
-
79957762484
-
Medicinal uses and pharmacological properties of Crocus sativus Linn (saffron)
-
Bhargava BK,. Medicinal uses and pharmacological properties of Crocus sativus Linn (saffron). Int J Pharm Pharm Sci 2011; 3: 22-26.
-
(2011)
Int J Pharm Pharm Sci
, vol.3
, pp. 22-26
-
-
Bhargava, B.K.1
-
103
-
-
85014478615
-
Anti-tumor activity of safranal against neuroblastoma cells
-
Suppl S2
-
Shoshtari ME, et al. Anti-tumor activity of safranal against neuroblastoma cells. Phcog Mag 2014; 10, Suppl S2: 419-424.
-
(2014)
Phcog Mag
, vol.10
, pp. 419-424
-
-
Shoshtari, M.E.1
-
104
-
-
78650715139
-
DNA fragmentation and cell cycle arrest: A hallmark of apoptosis induced by crocin from Kashmiri saffron in a human pancreatic cancer cell line
-
Bakshi H, et al. DNA fragmentation and cell cycle arrest: a hallmark of apoptosis induced by crocin from Kashmiri saffron in a human pancreatic cancer cell line. Asian Pac J Cancer Prev 2010; 11: 675-679.
-
(2010)
Asian Pac J Cancer Prev
, vol.11
, pp. 675-679
-
-
Bakshi, H.1
-
105
-
-
0028834324
-
Saffron chemoprevention in biology and medicine: A review
-
Nair SC, et al. Saffron chemoprevention in biology and medicine: a review. Cancer Biother 1995; 10: 257-264.
-
(1995)
Cancer Biother
, vol.10
, pp. 257-264
-
-
Nair, S.C.1
-
106
-
-
0001541587
-
Saffron in biological and medical research
-
Negbi M. ed. Amsterdam, The Netherlands: Harwood Academic Publishers
-
Abduallev FI, Frenkel GD,. Saffron in biological and medical research. In:, Negbi M, ed. Saffron Crocus sativus L. Amsterdam, The Netherlands: Harwood Academic Publishers, 1999: 103-113.
-
(1999)
Saffron Crocus Sativus L
, pp. 103-113
-
-
Abduallev, F.I.1
Frenkel, G.D.2
-
107
-
-
0034053334
-
Membrane associated antitumor effects of crocine-ginseniside- and cannabinoid derivates
-
Molnar J, et al. Membrane associated antitumor effects of crocine-ginseniside- and cannabinoid derivates. Anticancer Res 2000; 20 (2a): 861-867.
-
(2000)
Anticancer Res
, vol.20
, Issue.2 A
, pp. 861-867
-
-
Molnar, J.1
-
108
-
-
0032449901
-
Carotenoids and cancer: Prevention and potential therapy
-
Smith TAD,. Carotenoids and cancer: prevention and potential therapy. Br J Biomed Sci 1998; 55: 268-275.
-
(1998)
Br J Biomed Sci
, vol.55
, pp. 268-275
-
-
Smith, T.A.D.1
-
109
-
-
77958121951
-
Selective Th2 upregulation by Crocus sativus: A neutraceutical spice. Hindawi Publishing Corporation
-
: (Article ID 639862)
-
Bani S, et al. Selective Th2 upregulation by Crocus sativus: a neutraceutical spice. Hindawi Publishing Corporation. Evid Based Complement Alternat Med 2011; 2011: 1-9 (Article ID 639862).
-
(2011)
Evid Based Complement Alternat Med
, vol.2011
, pp. 1-9
-
-
Bani, S.1
-
110
-
-
84873396878
-
The potential effect of the extract of Crocus sativus and safranal on the toral and differential white blood cells of ovalbumine-sensitized Guinea pigs
-
Bayrami G, Boskabadi MH,. The potential effect of the extract of Crocus sativus and safranal on the toral and differential white blood cells of ovalbumine-sensitized guinea pigs. RPS 2012; 7: 249-255.
-
(2012)
RPS
, vol.7
, pp. 249-255
-
-
Bayrami, G.1
Boskabadi, M.H.2
-
111
-
-
84866739483
-
Effect of saffron on fluoxetine-induced sexual impairment in men: Randomized double-blind placebo-controlled trial
-
Modabbernia A, et al. Effect of saffron on fluoxetine-induced sexual impairment in men: randomized double-blind placebo-controlled trial. Psychopharmacology (Berl) 2012; 223: 381-388.
-
(2012)
Psychopharmacology (Berl)
, vol.223
, pp. 381-388
-
-
Modabbernia, A.1
-
112
-
-
84873099006
-
Saffron for treatment of fluoxetine-induced sexual dysfunction in women: Randomized double-blind placebo controlled study
-
Kashani L, et al. Saffron for treatment of fluoxetine-induced sexual dysfunction in women: randomized double-blind placebo controlled study. Hum Psychopharmacol Clin Exp 2013; 28: 54-60.
-
(2013)
Hum Psychopharmacol Clin Exp
, vol.28
, pp. 54-60
-
-
Kashani, L.1
-
113
-
-
67349105585
-
Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: A pilot study
-
Shamsa A, et al. Evaluation of Crocus sativus L. (saffron) on male erectile dysfunction: a pilot study. Phytomedicine 2009; 16: 690-693.
-
(2009)
Phytomedicine
, vol.16
, pp. 690-693
-
-
Shamsa, A.1
-
114
-
-
77954818224
-
An open label, randomized, fixeddose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus) for treating erectile dysfunction in men naive to treatment
-
Safarinejad MR, et al. An open label, randomized, fixeddose, crossover study comparing efficacy and safety of sildenafil citrate and saffron (Crocus sativus) for treating erectile dysfunction in men naive to treatment. Int J Impot Res 2010; 22: 240-250.
-
(2010)
Int J Impot Res
, vol.22
, pp. 240-250
-
-
Safarinejad, M.R.1
-
115
-
-
12744279391
-
Evaluation of subacute toxicity of aqueous extract of Crocus sativus L. Stigma and petal in rats
-
Karimi G, et al. Evaluation of subacute toxicity of aqueous extract of Crocus sativus L. stigma and petal in rats. J Med Plants 2004; 3: 29-35.
-
(2004)
J Med Plants
, vol.3
, pp. 29-35
-
-
Karimi, G.1
-
116
-
-
84870404779
-
Hepatoprotective potential of crocin and curcumin against iron overload-induced biochemical alterations in rat
-
El-Maraghy SA, et al. Hepatoprotective potential of crocin and curcumin against iron overload-induced biochemical alterations in rat. Afr J Biochem Res 2009; 3: 215-221.
-
(2009)
Afr J Biochem Res
, vol.3
, pp. 215-221
-
-
El-Maraghy, S.A.1
-
117
-
-
77957270539
-
Acute and sub-acute toxicity of crocin, a constituent of Crocus sativus L. (saffron), in mice and rats
-
Hosseinzadeh H, et al. Acute and sub-acute toxicity of crocin, a constituent of Crocus sativus L. (saffron), in mice and rats. Pharmacologyonline. 2010; 2: 934-951.
-
(2010)
Pharmacologyonline.
, vol.2
, pp. 934-951
-
-
Hosseinzadeh, H.1
-
118
-
-
84874692740
-
Acute and subacute toxicity of safranal, a constituent of saffron, in mice and rats
-
Hosseinzadeh H, et al. Acute and subacute toxicity of safranal, a constituent of saffron, in mice and rats. Iran J Pharm Res 2013; 12: 93-99.
-
(2013)
Iran J Pharm Res
, vol.12
, pp. 93-99
-
-
Hosseinzadeh, H.1
-
119
-
-
56549100087
-
Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers
-
Modaghegh MH, et al. Safety evaluation of saffron (Crocus sativus) tablets in healthy volunteers. Phytomedicine 2008; 15: 1032-1037.
-
(2008)
Phytomedicine
, vol.15
, pp. 1032-1037
-
-
Modaghegh, M.H.1
-
120
-
-
84872834747
-
Safety evaluation of crocin (a constituent of saffron) tablets in healthy volunteers
-
Mohamadpour AH, et al. Safety evaluation of crocin (a constituent of saffron) tablets in healthy volunteers. Iran J Basic Med Sci 2013; 16: 39-46.
-
(2013)
Iran J Basic Med Sci
, vol.16
, pp. 39-46
-
-
Mohamadpour, A.H.1
|