Blast from the Past: Reassessing Forgotten Translation Inhibitors, Antibiotic Selectivity, and Resistance Mechanisms to Aid Drug Development

Molecular Cell

Volumn 61, Issue 1, 2016, Pages 3-14

  Arenz, Stefan ^a   Wilson, Daniel N ^a  

^a UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBIOTIC A201A; ANTIBIOTIC AGENT; BACTOBOLIN A; DITYROMYCIN; GE 82832; HYGROMYCIN; ONCOCIN; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; PROTEIN SYNTHESIS INHIBITOR;

ANTIBIOTIC RESISTANCE; CYTOPLASM; DRUG SELECTIVITY; DRUG SPECIFICITY; EUKARYOTE; LARGE RIBOSOMAL SUBUNIT; MITOCHONDRION; MOLECULAR INTERACTION; MULTIDRUG RESISTANCE; NONHUMAN; PREVALENCE; REVIEW; RIBOSOME; ANIMAL; BACTERIUM; BIOSYNTHESIS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DEVELOPMENT; DRUG EFFECTS; GENETICS; HUMAN; METABOLISM; PROCEDURES; PROTEIN CONFORMATION; PROTEIN SYNTHESIS; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIA; BACTERIAL PROTEINS; DRUG DISCOVERY; DRUG RESISTANCE, BACTERIAL; HUMANS; MODELS, MOLECULAR; PROTEIN BIOSYNTHESIS; PROTEIN CONFORMATION; PROTEIN SYNTHESIS INHIBITORS; RIBOSOMES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84953639598     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2015.10.019     Document Type: Review

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