Amicoumacin A Inhibits Translation by Stabilizing mRNA Interaction with the Ribosome

Molecular Cell

Volumn 56, Issue 4, 2014, Pages 531-540

  Polikanov, Yury S ^a   Osterman, Ilya A ^b   Szal, Teresa ^c   Tashlitsky, Vadim N ^b   Serebryakova, Marina V ^b   Kusochek, Pavel ^b   Bulkley, David ^a,i   Malanicheva, Irina A ^d   Efimenko, Tatyana A ^d   Efremenkova, Olga V ^d   Konevega, Andrey L ^e,f   Shaw, Karen J ^g   Bogdanov, Alexey A ^b   Rodnina, Marina V ^h   Dontsova, Olga A ^b   Mankin, Alexander S ^c   Steitz, Thomas A ^a   Sergiev, Petr V ^b  

^a YALE UNIVERSITY   (United States)

^b MOSCOW STATE UNIVERSITY   (Russian Federation)

^c UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^d GAUSE INSTITUTE OF NEW ANTIBIOTICS   (Russian Federation)

^e PETERSBURG NUCLEAR PHYSICS INSTITUTE   (Russian Federation)

^f PETER THE GREAT ST PETERSBURG POLYTECHNIC UNIVERSITY   (Russian Federation)

^g Hearts Consulting Group   (United States)

^h MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

ⁱ UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMICOUMACIN A; ANTIBIOTIC AGENT; BACTERIAL PROTEIN; ELONGATION FACTOR G; MESSENGER RNA; PACTAMYCIN; RNA 16S; TRANSFER RNA; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; COUMARIN DERIVATIVE; PROTEIN SYNTHESIS INHIBITOR;

ARTICLE; BACTERIAL GENE; GENE MUTATION; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PROTEIN BINDING; PROTEIN SYNTHESIS; RIBOSOME; RIBOSOME SUBUNIT; RNA TRANSLATION; SMALL RIBOSOMAL SUBUNIT; ANTIBIOTIC RESISTANCE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; ESCHERICHIA COLI; GENETICS; LARGE RIBOSOMAL SUBUNIT; METABOLISM; MICROBIAL SENSITIVITY TEST; NUCLEOTIDE SEQUENCE; RNA STABILITY; STAPHYLOCOCCUS AUREUS; THERMUS THERMOPHILUS; X RAY CRYSTALLOGRAPHY;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BASE SEQUENCE; BINDING SITES; COUMARINS; CRYSTALLOGRAPHY, X-RAY; DRUG RESISTANCE, BACTERIAL; ESCHERICHIA COLI; MICROBIAL SENSITIVITY TESTS; MODELS, MOLECULAR; PEPTIDE ELONGATION FACTOR G; PROTEIN BIOSYNTHESIS; PROTEIN SYNTHESIS INHIBITORS; RIBOSOME SUBUNITS, LARGE, BACTERIAL; RIBOSOME SUBUNITS, SMALL, BACTERIAL; RNA STABILITY; RNA, MESSENGER; STAPHYLOCOCCUS AUREUS; THERMUS THERMOPHILUS;

EID: 84912522222     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2014.09.020     Document Type: Article

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