Proline-rich antimicrobial peptides: Potential therapeutics against antibiotic-resistant bacteria

Amino Acids

Volumn 46, Issue 10, 2014, Pages 2287-2294

  Li, Wenyi ^a   Tailhades, Julien ^a   O'Brien Simpson, Neil M ^b,c   Separovic, Frances ^a,b   Otvos, Laszlo ^d   Hossain, M Akhter ^a   Wade, John D ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF MELBOURNE   (Australia)

^c UNIVERSITY OF MELBOURNE   (Australia)

^d Temple University   (United States)

Author keywords

Cell penetration; Immunostimulation; Membrane disruption; Non lytic mechanism; Proline rich antimicrobial peptides

Indexed keywords

ADENOSINE PHOSPHATE; CELL PENETRATING PEPTIDE; CYTOKINE; LIPOPOLYSACCHARIDE; POLYPEPTIDE ANTIBIOTIC AGENT; PROLINE RICH ANTIMICROBIAL PEPTIDE; UNCLASSIFIED DRUG; ANTIINFECTIVE AGENT; ANTIMICROBIAL CATIONIC PEPTIDE; IMMUNOLOGIC FACTOR;

ANGIOGENESIS; BACTERIAL INFECTION; BINDING AFFINITY; BLOOD BRAIN BARRIER; CELL MEMBRANE; CONCENTRATION (PARAMETERS); DRUG DELIVERY SYSTEM; DRUG MECHANISM; HOST RESISTANCE; IMMUNE SYSTEM; IMMUNOSTIMULATION; MEMBRANE BINDING; NONHUMAN; REVIEW; ANIMAL; ANTIBIOTIC RESISTANCE; BACTERIAL INFECTIONS; CELL MEMBRANE PERMEABILITY; CHEMISTRY; DRUG EFFECTS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; GROWTH, DEVELOPMENT AND AGING; HUMAN; IMMUNOLOGY; MICROBIOLOGY; PROLINE RICH PROTEIN DOMAIN;

BACTERIA (MICROORGANISMS); HEXAPODA;

ANIMALS; ANTI-BACTERIAL AGENTS; ANTIMICROBIAL CATIONIC PEPTIDES; BACTERIAL INFECTIONS; CELL MEMBRANE PERMEABILITY; DRUG DELIVERY SYSTEMS; DRUG RESISTANCE, BACTERIAL; GRAM-NEGATIVE BACTERIA; GRAM-POSITIVE BACTERIA; HUMANS; IMMUNOLOGIC FACTORS; PROLINE-RICH PROTEIN DOMAINS;

EID: 84919909276     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-014-1820-1     Document Type: Review

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