Structural and functional characterization of the bacterial translocation inhibitor GE82832

FEBS Letters

Volumn 586, Issue 19, 2012, Pages 3373-3378

  Brandi, Letizia ^a,d   Maffioli, Sonia ^b,d   Donadio, Stefano ^b   Quaglia, Fabio ^a   Sette, Marco ^c   Milón, Pohl ^a   Gualerzi, Claudio O ^a   Fabbretti, Attilio ^a  

^a UNIVERSITY OF CAMERINO   (Italy)

^b NAICONS Srl   (Italy)

^c UNIVERSITY OF ROME TOR VERGATA   (Italy)

^d MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

Author keywords

Dityromycin; Natural product; Ribosome; Translation; Translocation inhibitor

Indexed keywords

AMINOACYL TRANSFER RNA; ANTIBIOTIC AGENT; DITYROMYCIN; GE 82832; GUANOSINE TRIPHOSPHATE; MEMBRANE PROTEIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL; POLYPEPTIDE ANTIBIOTIC AGENT; PROTEIN S13; RNA 16S; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL TRANSLOCATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; DRUG STRUCTURE; HYDROLYSIS; IN VITRO STUDY; INHIBITION KINETICS; MASS SPECTROMETRY; PRIORITY JOURNAL; RIBOSOME; RNA TRANSLATION; RNA TRANSPORT; SOIL MICROFLORA; STRUCTURE ACTIVITY RELATION; TRANSLATION REGULATION;

ACTINOMYCETALES; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TRANSLOCATION; GUANOSINE TRIPHOSPHATE; KINETICS; MODELS, MOLECULAR; MOLECULAR STRUCTURE; PEPTIDE ELONGATION FACTOR G; PEPTIDES; RIBOSOMES; SOIL MICROBIOLOGY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

BACTERIA (MICROORGANISMS);

EID: 84866625243     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.07.040     Document Type: Article

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