Inhibition of the ribosomal peptidyl transferase reaction by the mycarose moiety of the antibiotics carbomycin, spiramycin and tylosin

Journal of Molecular Biology

Volumn 304, Issue 3, 2000, Pages 471-481

  Poulsen, Susan M ^a   Kofoed, Christine ^a   Vester, Birte ^a  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Hygromycin A; Macrolide; Peptidyl transferase; Ribosome

Indexed keywords

ANTIBIOTIC AGENT; CARBOMYCIN; CHALCOMYCIN; DESMYCOSIN; ERYTHROMYCIN; HYGROMYCIN; MACROLIDE; NUCLEOTIDE; PEPTIDYLTRANSFERASE; RNA 23S; SPIRAMYCIN; SUGAR; TYLOSIN;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DRUG PROTEIN BINDING; ENZYME INHIBITION; ENZYME MECHANISM; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RIBOSOME; STRUCTURE ACTIVITY RELATION;

ESCHERICHIA COLI;

EID: 0034406527     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1006/jmbi.2000.4229     Document Type: Article

References (38)

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